THE  JOHN  SCOTT  AWARD
PHILADELPHIA, PA

Award Recipients




2014

Dr. Susan B. Horowitz
Albert Einstein College of Medicine, NY
Distinguished Professor & Co-Chair, Department of Molecular Pharmacology
Rose C. Falkenstein Chair in Cancer Research
Past President, American Association for Cancer Research

Recognized for her groundbreaking research in the development of drugs derived from natural products  for the treatment of malignancies and on the challenges of dealing with the emergence of drug resistance in cancer.
 
Dr. Leonard Hayflick
Professor of Anatomy, School of Medicine, University of California, San Francisco, CA.
Fellow of the American Association for the Advancement of Science
Founding Member, Council of the National Institute on Aging
Past President, Gerontological Society of America

Recognized for their pioneering work discovery that, unline immortal cancer cells, normal human cells are mortal.  His interpretation of mortality as cellular aging established the modern era of aging research, and his development of a human cell strain used to make most human virus vaccines has benefitted billions world-wide.   He is the author of the best-selling book, "How and Why We Age," which has sbeen translated into nine languages.

Dr. Paul S. Moorhead
Emeritus Professor of Genetics,
University of Pennsylvania, Philadelphia, PA
Past Director, Clinical Cytogenetics Lab at Children's Hospital, Philadelphia
Past Supervisor, University of Pennsylvania, School of Veterinary Medicine Cytogenetics Lab.

Recognized for his work at the Wistar Institute  with Dr. Leonard Hayflick in the discovery that normal human cells are mortal, as well as his development of a technique for microscopically visualizing human and animal chromosomes that became a standard world-wide.  The paper Dr. Moorhead co-authored in 1961 with Dr. Hayflick, "The serial cultivation of human diploid cell strains," has become one of the most frequently cited scientific papers in modern history.  Dr. Moorhead won the National Institutes of Health Career Development Award on three separate occasions.



2013


Dr, N. Scott Adzick
C.Everett Koop Professor of Pediatric Surgery at Children's Hospital of Philadelphia (CHOP)
Surgeon-in-Chief, CHOP
Director, Division of Pediatric General, Thoracic and Fetal Surgery
Professor, Pediatrics, Obstetrics & Cynecology, Perelman School of Medicine
University of Pennsylvania, Philadelphia, PA

Recognized for his contributions to the practice of fetal surgery, exploring cutting edge surgical treatment options for life-threatening fetal anatomic malformations.
 
Dr. P. Leslie Dutton
Eldridge Reeves Johnson Professor of Biochemistry & Biophysics
Director, Johnson Foundation of Molecular Biophysics
Perelman School of Medicine
University of Pennsylvania
Philadelphia, PA

Fellow of the Royal Society
Recognized for his work on the elementary processes of oxidation-reduction and the diverse biological events coupled to them.




Dr. Robert L. Brent
Head of Clinical & Environmental Teratology Research Lab
A.I. duPont Hospital for Children
Distinguished Professor of Pediatrics, Radiology & Pathology
Thomas Jefferson University
Philadelphia, PA

Member, Institute of Medicine, National Academy of Sciences
Recognized for his work on environmental causes of birth defects including exposure to drugs, chemicals, and ionizing radiation.


2012


Dr. Paul J. Steinhardt
Albert Einstein Professor in Science
Director, Princeton Center for Theoretical Science
Princeton University
Princeton, NJ
He is also on the faculty of both the departments of Physics and Astrophysical Sciences.
Recognized for his pioneering achievements in developing the theory of quasicrystals and for co-discovering the   first natural quasicrystals. 
He shared the P.A.M. Dirac Medal from the International Centre for Theoretical Physics in 2002 for his contribution to the development of the inflationary model of the universe, and received the Oliver E. Buckley Prize of the American Physical Society in 2010 for his contribution to the theory of quasicrystals.  He is the author of over 200 refereed articles, several technical books and numerous popular articles.

 
Dr. John Q. Trojanowski & Dr. Virginia Man-Yee Lee
Dr. Lee is the Director and
Dr. Trojanowski is the Co-Director
Center for Neurodegenerative Disease Research (CNDR)
University of Pennsylvania
Perelman School of Medicine
Philadelphia, PA
Recognized for their groundbreaking research into the treatment of neurodegenerative diseases.
Dr. Trojanowski's  research centers on molecular mechanisms of neuron dysfunction, degeneration and death in normal aging and in neurodegenerative diseases.  Dr. D.Lee's research focuses on disease proteins that form pathological inclusions in hereditary and sporadic Alzheimer's disease, Parkinson's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis and related neurodegenerative disorders of aging.  Their research provides critical evidence for the direction of new areas of research that are needed to identify targets and create better treatments for these debilitating diseases.



2011


Dr. David E. Kuhl
Dr. Kuhl served as the Chief of the Division of Nuclear Medicine at the University of Michigan for 20 years and retired in 2011

Recognized for his groundbreaking work in positron emission tomography (PET). He pioneered the development of single proton emission computer tomography (SPECT), which led to PET.  He remains a leading researcher in PET applications, particularly in the study of cardiovascular and brain function.  His research is focused on introducing new measures of neurochemical and metabolic processes determined within the living brain, using radioactive molecular tracers and emission reconstruction tomography.  He has also received the Japan Prize for his contributions to tomographic imaging in nuclear medicine and was elected to the Institute of Medicine of the National Academy of Sciences.  He holds memberships and leadership positions in professional societies, including the American College of Radiology, American Institute of Medical and Biological Engineering, the Society of Nuclear Medicine, and the Association of University Radiologists.
Dr. Jenny Pickworth Glusker
Fox Chase Cancer Center
Philadelphia , PA
Recognized for her pioneering work in determining the three-dimensional structure of biologically important molecules.  Dr. Glusker determined the molecular structure of a hexacarboxylic acid, derived from Vitamin B12, which led to the determination of the previously unknown chemical formula of Vitamin B12, the "anti-pernicious anemia factor," the largest molecular structure to be determined by x-ray diffraction methods as the time.  Her work on the molecular structure of components of the Krebs cycle provided critical new insights into the molecular and biochemical aspects of metabolism.  Her impact on our knowledge of the causes and possible treatment of cancer continued with her determination of the structures of numerous anti-tumor agents and important mutagens, including the polycyclic aromatic hydrocarbons benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene, which are the major carcinogens in tobacco smoke.  Her novel triangular plots to represent the positions of metal ions with respect to the three most likely binding atoms in proteins, oxygen, nitrogen and sulfur, and her skillful analyses have greatly expanded our understanding and appreciation of the roles of metals in catalysis.