Fri Aug 1 15:56:46 2003

Initial sequencing and analysis of the human genome
by ES Lander et al.
NATURE
409 (6822): 860-921 FEB 15 2001

Nodes: 2387
Sorted by year, journal, volume, page.
Page 1: 1 2 3 4 5

#	Cited nodes	Nodes / Authors	GCS	LCS
1	2	1 2000 BIOPOLYMERS 56(3):209-227 Shafer RH; Smirnov I Biological aspects of DNA/RNA quadruplexes	3	0
2	2	2 2001 AAPS PHARMSCI 3(3):art. no.-22 Sadee W; Hoeg E; Lucas J; Wang DX Genetic variations in human G protein-coupled receptors: Implications for drug therapy	1	0
3	2	3 2001 ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 57():1836-1842 Von Dreele RB Binding of N-acetylglucosamine to chicken egg lysozyme: a powder diffraction study	3	0
4	2	4 2001 ALIMENTARY PHARMACOLOGY & THERAPEUTICS 15(6):731-748 Ahmad T; Satsangi J; Mcgovern D; Bunce M; Jewell DP Review Article: The genetics of inflammatory bowel disease	21	0
5	1	5 2001 AMERICAN JOURNAL OF HUMAN GENETICS 68(6):1535-1537 Giannelli F Mitochondria and the quality of human gametes	0	0
6	1	6 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(1):25-34 Ahmed ZM; Riazuddin S; Bernstein SL; Ahmed Z; Khan S; Griffith AJ; Morell RJ; Friedman TB; Riazuddin S; Wilcox ER Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F	34	1
7	2	7 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(1):159-178 Rannala B; Reeve JP High-resolution multipoint linkage-disequilibrium mapping in the context of a human genome sequence	13	3
8	2	8 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(2):361-370 Krawczak M; Cooper DN; Schmidtke J Estimating the efficacy and efficiency of cascade genetic screening	3	0
9	2	9 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):516-527 Jenne DE; Tinschert S; Reimann H; Lasinger W; Thiel G; Hameister H; Kehrer-Sawatzki H Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions	11	4
10	1	10 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):553-569 Wiltshire S; Hattersley AT; Hitman GA; Walker M; Levy JC; Sampson M; O'Rahilly S; Frayling TM; Bell JI; Lathrop GM; Bennett A; Dhillon R; Fletcher C; Groves CJ; Jones E; Prestwich P; Simecek N; Rao PVS; Wishart M; Foxon R; Howell S; Smedley D; Cardon LR; Menzel S; McCarthy MI A genomewide scan for loci predisposing to type 2 diabetes in a UK population (the Diabetes UK Warren 2 repository): Analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q	41	4
11	1	11 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(3):582-589 Ardlie K; Liu-Cordero SN; Eberle MA; Daly M; Barrett J; Winchester E; Lander ES; Kruglyak L Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion	22	3
12	2	12 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(4):791-803 Atkinson TP; Schaffer AA; Grimbacher B; Schroeder HW; Woellner C; Zerbe CS; Puck JM An immune defect causing dominant chronic mucocutaneous candidiasis and thyroid disease maps to chromosome 2p in a single family	3	0
13	1	13 2001 AMERICAN JOURNAL OF HUMAN GENETICS 69(5):1002-1012 Lefevre C; Jobard F; Caux F; Bouadjar B; Karaduman A; Heilig R; Lakhdar H; Wollenberg A; Verret JL; Weissenbach J; Ozguc M; Lathrop M; Prud'homme JF; Fischer J Mutations in CGI-58, the gene encoding a new protein of the esterase/lipase/thioesterase subfamily, in Chanarin-Dorfman syndrome	7	0
14	3	14 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 106(3):223-232 Greendale K; Pyeritz RE Empowering primary care health professionals in medical genetics: How soon? How fast? How far?	8	0
15	1	15 2001 AMERICAN JOURNAL OF PATHOLOGY 158(5):1639-1651 Young AN; Amin MB; Moreno CS; Lim SD; Cohen C; Petros JA; Marshall FF; Neish AS Expression profiling of renal epithelial neoplasms - A method for tumor classification and discovery of diagnostic molecular markers	24	0
16	2	16 2001 AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 281(5):C1587-C1595 Zhao BT; Bowden RA; Stavchansky SA; Bowman PD Human endothelial cell response to gram-negative lipopolysaccharide assessed with cDNA microarrays	12	1
17	2	17 2001 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 281(4):H1465-H1468 Heusch G; Erbel R; Siffert W Genetic determinants of coronary vasomotor tone in humans	4	0
18	1	18 2001 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 281(5):F781-F794 Gamba G Alternative splicing and diversity of renal transporters	5	1
19	2	19 2001 AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 281(6):F1148-F1156 Stuart RO; Pavlova A; Beier D; Li ZX; Krijanovski Y; Nigam SK EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis	0	0
20	2	20 2001 ANALYTICAL BIOCHEMISTRY 297(1):79-85 Knaust RKC; Nordlund P Screening for soluble expression of recombinant proteins in a 96-well format	6	2
21	2	21 2001 ANALYTICAL CHEMISTRY 73(9):1917-1926 Shevchenko A; Sunyaev S; Loboda A; Shevehenko A; Bork P; Ens W; Standing KG Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time of flight mass spectrometry and BLAST homology searching	29	2
22	2	22 2001 ANATOMICAL RECORD 265(4):193-201 Weber GW Virtual anthropology (VA): A call for glasnost in paleoanthropology	1	0
23	2	23 2001 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 40(18):3341-+ Wess G; Urmann M; Sickenberger B Medicinal chemistry: Challenges and opportunities	15	1
24	2	24 2001 ANNALES CHIRURGIAE ET GYNAECOLOGIAE 90(1):3-3 Roberts PJ Human genome project	0	0
25	1	25 2001 ANNALS OF MEDICINE 33(4):248-256 Jones I; Craddock N Candidate gene studies of bipolar disorder	3	0
26	2	26 2001 ANNALS OF MEDICINE 33(4):272-285 Detera-Wadleigh SD Lithium-related genetics of bipolar disorder	9	0
27	2	27 2001 ANNALS OF SURGERY 234(6):769-778 Friess H; Ding JY; Kleeff J; Liao Q; Berberat PO; Hammer J; Buchler MW Identification of disease-specific genes in chronic pancreatitis using DNA array technology	5	0
28	6	28 2001 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36 36():201-210 Pollock S; Safer HM Chapter 20. Bioinformatics in the drug discovery process	0	0
29	1	29 2001 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 36 36():211-225 Jones DT; Swindells MB; Fagan R Chapter 21. The role of protein structure prediction in drug discovery	0	0
30	2	30 2001 ANNUAL REVIEW OF GENETICS 35():303-339 Mackay TFC The genetic architecture of quantitative traits	26	0
31	1	31 2001 ANNUAL REVIEW OF GENETICS 35():501-538 Ostertag EM; Kazazian HH Biology of mammalian L1 retrotransposons	27	17
32	1	32 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():1-8 Ruddle F Hundred-year search for the human genome	0	0
33	2	33 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():259-269 Tang CM; Moxon ER The impact of microbial genomics on antimicrobial drug development	3	1
34	2	34 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():343-372 Ideker T; Galitski T; Hood L A new approach to decoding life: Systems biology	34	4
35	3	35 2001 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 2():493-510 Mombaerts P The human repertoire of odorant receptor genes and pseudogenes	9	2
36	2	36 2001 ANTI-CANCER DRUG DESIGN 16(6):291-303 McCluskey A; Ackland SP; Gardiner E; Walkom CC; Sakoff JA The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?	0	0
37	1	37 2001 APPLIED ARTIFICIAL INTELLIGENCE 15(10):917-947 Bryson K; Luck M; Joy M; Jones DT Agent interaction for bioinformatics data management	0	0
38	1	38 2001 ARCHIVES OF DERMATOLOGY 137(11):1515-1519 Niendorf KB; Shannon KM The role of genetic testing and effect on patient care	0	0
39	2	39 2001 ARCHIVES OF NEUROLOGY 58(11):1739-1741 Rosenberg RN Genomic neurology: A new beginning	2	0
40	2	40 2001 ARCHIVES OF NEUROLOGY 58(11):1748-1749 Hardy J The human genome is sequenced - What does it mean and why is it important?	0	0
41	2	41 2001 ARCHIVES OF NEUROLOGY 58(11):1750-1751 Puls I; Lieberman AP; Fischbeck KH Impact of the human genome sequence on neurology and neuroscience	0	0
42	4	42 2001 ARCHIVES OF NEUROLOGY 58(11):1755-1757 Pulst SM Genomes, neuroscience, and neurology	0	0
43	2	43 2001 ARCHIVES OF NEUROLOGY 58(11):1758-1759 Tsuji S Neurogenetics in the postgenomic era	0	0
44	3	44 2001 ARCHIVES OF NEUROLOGY 58(11):1772-1778 Cravchik A; Subramanian G; Broder S; Venter JC Sequence analysis of the human genome - Implications for the understanding of nervous system function and disease	7	4
45	2	45 2001 ARCHIVES OF OPHTHALMOLOGY 119(11):1710-1711 Wiggs JL The Human Genome Project and eye disease - Clinical implications	0	0
46	1	46 2001 ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE 155(11):1193-1194 Murray JC The unending string	0	0
47	1	47 2001 ATHEROSCLEROSIS VI 947():254-258 Sakaki Y Genomics and atherosclerosis	0	0
48	2	48 2001 ATHEROSCLEROSIS VI 947():382-386 Yonekura H; Yasui K; Sakurai S; Li H; Yamamoto Y; Yamamoto H Antisense display: A new method for functional gene screen and its application to angiogenesis-related gene isolation	0	0
49	2	49 2001 BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM 15(3):293-308 Gloyn AL; McCarthy MI The genetics of type 2 diabetes	3	1
50	1	50 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(2):499-506 Lieberman AP; Friedlich DL; Harmison G; Howell BW; Jordan CL; Breedlove SM; Fischbeck KH Androgens regulate the mammalian homologues of invertebrate sex determination genes tra-2 and fox-1	2	1
51	1	51 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 282(4):928-933 Bartes A; Bhakta S; Hemmerich S Sulfation of endothelial mucin by corneal keratan N- acetylglucosamine 6-O-sulfotransferase (GST-4 beta)	7	0
52	1	52 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 285(5):1150-1154 Koenig U; Eckhart L; Tschachler E Evidence that caspase-13 is not a human but a bovine gene	3	1
53	2	53 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(3):547-553 Tanaka M; Tanaka T; Kijima H; Itoh J; Matsuda T; Hori S; Yamamoto M Characterization of tissue- and cell-type-specific expression of a novel human septin family gene, Bradeion	1	0
54	1	54 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(5):863-868 Asakawa S; Tsunematsu K; Takayanagi A; Sasaki T; Shimizu A; Shintani A; Kawasaki K; Mungall AJ; Beck S; Minoshima S; Shimizu N The genomic structure and promoter region of the human Parkin gene	6	1
55	2	55 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 286(5):880-885 Monkley SJ; Pritchard CA; Critchley DR Analysis of the mammalian talin2 gene TLN2	4	0
56	3	56 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(2):362-370 Popovici C; Leveugle M; Birnbaum D; Coulier F Coparalogy: Physical and functional clusterings in the human genome	7	3
57	2	57 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 288(4):933-939 Yabuuchi H; Shimizu H; Takayanagi S; Ishikawa T Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12	12	0
58	2	58 2001 BIOCHEMICAL PHARMACOLOGY 62(10):1311-1336 Clarke PA; Poele RT; Wooster R; Workman P Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential	31	5
59	2	59 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():27-31 Sulston J; Int Human Genome Sequencing Consor Society and the human genome	0	0
60	1	60 2001 BIOCHEMICAL SOCIETY TRANSACTIONS 29():377-384 Lemmon MA; Ferguson KM Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides	12	0
61	5	61 2001 BIOCHEMISTRY-MOSCOW 66(10):1144-1152 Hofmann E What can medicine learn from the human DNA sequence?	1	0
62	2	62 2001 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1521(1-3):81-88 Matsugi J; Murao K Study on construction of a cDNA library corresponding to an amino acid-specific tRNA and influence of the modified nucleotide upon nucleotide misincorporations in reverse transcription	1	0
63	2	63 2001 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1522(3):230-237 Rue SW; Kim BW; Jun DY; Kim YH Nucleotide sequence and cell cycle-associated differential expression of ZF5128, a novel Kruppel type zinc finger protein gene	0	0
64	3	64 2001 BIOESSAYS 23(6):473-476 Nal B; Mohr E; Ferrier P Location analysis of DNA-bound proteins at the whole-genome level: untangling transcriptional regulatory networks	5	1
65	2	65 2001 BIOESSAYS 23(12):1131-1137 Wade PA Methyl CpG-binding transcriptional proteins and repression	20	2
66	2	66 2001 BIOFUTUR 2001(216):39-43 Graveley BR Alternative splicing: Through the proteome jungle	0	0
67	4	67 2001 BIOFUTUR 2001(209):49-55 Weissenbach J; Esnault Y First lessons from the human genome	0	0
68	2	68 2001 BIOINFORMATICS 17(4):299-299 States D Time to defend what we have won	1	0
69	4	69 2001 BIOINFORMATICS 17(7):581-586 Ke XY; Tapper W; Collins A LDB2000: sequence-based integrated maps of the human genome	2	1
70	1	70 2001 BIOINFORMATICS 17(7):642-645 Gorodkin J; Zwieb C; Knudsen B Semi-automated update and cleanup of structural RNA alignment databases	2	0
71	2	71 2001 BIOINFORMATICS 17(10):878-889 Frith MC; Hansen U; Weng ZP Detection of cis-element clusters in higher eukaryotic DNA	18	4
72	2	72 2001 BIOINFORMATICS 17(10):988-996 Rzhetsky A; Gomez SM Birth of scale-free molecular networks and the number of distinct DNA and protein domains per genome	14	3
73	1	73 2001 BIOLOGICHESKIE MEMBRANY 18(3):240-248 Rodionov AV; Punina EO; Chupov VS Evolution of the longitudional differentiation of plant chromosomes	1	0
74	1	74 2001 BIOMETALS 14(3-4):187-190 Maret W Zinc biochemistry, physiology, and homeostasis - recent insights and current trends	2	0
75	1	75 2001 BIOPHYSICAL JOURNAL 81(4):2268-2277 Gao M; Lu H; Schulten K Simulated refolding of stretched titin immunoglobulin domains	4	0
76	2	76 2001 BIOPOLYMERS 60(3):220-228 Ting AY; Witte K; Shah K; Kraybill B; Shokat KM; Schultz PG Phage-display evolution of tyrosine kinases with altered nucleotide specificity	2	1
77	3	77 2001 BIOPOLYMERS 60(5):334-350 Naider F; Arshava B; Ding FX; Arevalo E; Becker JM Peptide fragments as models to study the structure of a G- protein coupled receptor: The alpha-factor receptor of Saccharomyces cerevisiae	2	0
78	2	78 2001 BIOTECHNIQUES 30(3):626-+ Sawyer TK Cancer - Emerging breakthrough drugs	3	1
79	3	79 2001 BIOTECHNIQUES 30(5):1086-+ Sawyer TK Deciphering therapeutic targets	0	0
80	2	80 2001 BIOTECHNIQUES 31(1):156-+ Sawyer TK Proteomics - Structure and function	1	0
81	1	81 2001 BIOTECHNIQUES 31(3):636-+ Zagursky RJ; Russell D Bioinformatics: Use in bacterial vaccine discovery	0	0
82	2	82 2001 BIPOLAR DISORDERS 3(6):276-283 Berrettini WH Molecular linkage studies of bipolar disorders	3	0
83	1	83 2001 BJU INTERNATIONAL 88():11-17 Masuho Y; Matsumoto S; Isogai T; Nagai K; Nagahari K The search for drug target molecules from genomics	1	1
84	2	84 2001 BLOOD 98(4):1127-1134 Nakajima T; Matsumoto K; Suto H; Tanaka K; Ebisawa M; Tomita H; Yuki K; Katsunuma T; Akasawa A; Hashida R; Sugita Y; Ogawa H; Ra C; Saito H Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells	6	2
85	2	85 2001 BLOOD CELLS MOLECULES AND DISEASES 27(5):950-959 Rodriguez-Mari A; Diaz-Font A; Chabas A; Pastores GM; Grinberg D; Vilageliu L New insights into the origin of the Gaucher disease-causing mutation N370S: Extended haplotype analysis using the 5GC3.2, 5470 G/A, and ITG6.2 polymorphisms	1	0
86	2	86 2001 BOLLETTINO DELLA UNIONE MATEMATICA ITALIANA 4A(1):33-62 Giancarlo R; Mantaci S Contributions of the mathematical and information sciences to large-scale genome sequencing	0	0
87	2	87 2001 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 52(4):345-347 Pirmohamed M Pharmacogenetics and pharmacogenomics	3	0
88	2	88 2001 BRITISH MEDICAL JOURNAL 322(7293):1031-1034 Mathew C Science medicine and the future - Postgenomic technologies: hunting the genes for common disorders	8	2
89	2	89 2001 BRITISH MEDICAL JOURNAL 323(7313):611-615 Aitman TJ Science, medicine, and the future - DNA microarrays in medical practice	13	0
90	2	90 2001 BULLETIN OF MATHEMATICAL BIOLOGY 63(5):933-950 Fang Y; Wilson SR On cloning and clone libraries for finite and infinite length genomes	0	0
91	1	91 2001 CANADIAN JOURNAL ON AGING-REVUE CANADIENNE DU VIEILLISSEMENT 20():149-159 Charness N Commentary: A historical perspective on the US-Canada connection in the psychology of aging	0	0
92	2	92 2001 CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 10(7):733-741 Risch N The genetic epidemiology of cancer: Interpreting family and twin studies and their implications for molecular genetic approaches	36	2
93	2	93 2001 CANCER JOURNAL 7(4):324-337 Laheru D; Biedrzycki B; Jaffee EM Immunologic approaches to the management of pancreatic cancer	2	0
94	2	94 2001 CANCER RESEARCH 61(18):6640-6648 Bullrich F; Fujii H; Calin G; Mabuchi H; Negrini M; Pekarsky Y; Rassenti L; Alder H; Reed JC; Keating MJ; Kipps TJ; Croce CM Characterization of the 13q14 tumor suppressor locus in CLL: Identification of ALT1, an alternative splice variant of the LEU2 gene	7	1
95	1	95 2001 CANCER RESEARCH 61(19):7118-7121 Poignee M; Backsch C; Beer K; Jansen L; Wagenbach N; Stanbridge EJ; Kirchmayr R; Schneider A; Durst M Evidence for a putative senescence gene locus within the chromosomal region 10p14-p15	9	0
96	2	96 2001 CELL 104(4):465-467 Davies K After the genome: DNA and human disease	2	0
97	1	97 2001 CELL 105(2):173-176 Sternberg PW Working in the post-genomic C-elegans world	14	3
98	2	98 2001 CELL 106(1):9-11 Madhani HD Accounting for specificity in receptor tyrosine kinase signaling	5	0
99	1	99 2001 CELL 106(2):171-182 Derkatch IL; Bradley ME; Hong JY; Liebman SW Prions affect the appearance of other prions: The story of [PIN+]	22	1
100	2	100 2001 CELL 106(3):367-379 Gratacos M; Nadal M; Martin-Santos R; Pujana MA; Gago J; Peral B; Armengol L; Ponsa I; Miro R; Bulbena A; Estivill X A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders	39	10

# Cited
nodes Nodes / Authors GCS LCS
101 2 101 2001 CELL 106(4):391-394
Hastie ND
Life, sex, and WT1 isoforms - Three amino acids can make all the difference 13 2
102 2 102 2001 CELL 106(4):413-415
Hogenesch JB; Ching KA; Batalov S; Su AI; Walker JR; Zhou YY; Kay SA; Schultz PG; Cooke MP
A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes 95 62
103 3 103 2001 CELL 106(5):619-632
Dong XZ; Han SK; Zylka MJ; Simon MI; Anderson DJ
A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons 17 2
104 1 104 2001 CELL 107(1):13-16
Hamilton BA; Frankel WN
Of mice and genome sequence 9 2
105 2 105 2001 CELL 107(2):195-207
Billuart P; Winter CG; Maresh A; Zhao XS; Luo LQ
Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway 33 1
106 2 106 2001 CELL BIOCHEMISTRY AND BIOPHYSICS 35(1):35-47
Zhou HX; Wang GL
Predicted structures of two proteins involved in human diseases 1 0
107 2 107 2001 CELLULAR AND MOLECULAR BIOLOGY 47(8):1301-1308
Guillouzo A
Applications of biotechnology to pharmacology and toxicology 0 0
108 2 108 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(7):868-884
Jonsson AP
Mass spectrometry for protein and peptide characterisation 12 1
109 2 109 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(14):2085-2097
Li D; Roberts R
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases 7 0
110 2 110 2001 CHEMICAL INNOVATION 31(4):1-1
Block MJ
Doing the genome thing 0 0
111 2 111 2001 CHEMICAL INNOVATION 31(6):29-32
Hutton S
Back to biotech basics on the Internet 0 0
112 1 112 2001 CHEMICAL REVIEWS 101(8):2313-2340
Jackson MD; Denu JM
Molecular reactions of protein phosphatases - Insights from structure and chemistry 14 1
113 2 113 2001 CHEMISTRY & BIOLOGY 8(10):931-939
Famulok M; Blind M; Mayer G
Intramers as promising new tools in functional proteomics 13 0
114 2 114 2001 CHIMIA 55(6):487-492
Richmond TJ
The structural basis of gene regulation for DNA organized as chromatin 0 0
115 2 115 2001 CHIMICA OGGI-CHEMISTRY TODAY 19(5):15-17
Stewart L; Moran S
Advances in high-throughput crystallization 0 0
116 2 116 2001 CHINESE SCIENCE BULLETIN 46(23):1937-1942
Yu J; Hu SN; Wang J; Li SG; Wong KSG; Liu B; Deng Y; Dai L; Zhou Y; Zhang XQ; Cao ML; Liu J; Sun JD; Tang JB; Chen YJ; Huang XB; Lin W; Ye C; Tong W; Cong LJ; Geng JN; Han YJ; Li L; Li W; Hu GQ; Huang XG; Li WJ; Li J; Liu ZW; Li L; Liu JP; Qi QH; Liu JS; Li L; Wang XG; Lu H; Wu TT; Zhu M; Ni PX; Han H; Dong W; Ren XY; Feng XL; Cui P; Li XR; Wang H; Xu X; Zhai WX; Xu Z; Zhang JS; He SJ; Zhang JG; Xu JC; Zhang KL; Zheng XW; Dong JH; Zeng WY; Tao L; Chen XW; He J; Liu DF; Tian W; Tian CG; Xia HG; Li G; Gao H; Li P; Chen W; Wang XD; Zhang Y; Hu JF; Wang J; Liu S; Yang J; Zhang GY; Xiong YQ; Li ZJ; Mao L; Zhou CS; Zhu Z; Chen RS; Hao BL; Zheng WM; Chen SY; Guo W; Li GJ; Liu SQ; Huang GY; Tao M; Wang J; Zhu LH; Yuan LP; Yang HM
A draft sequence of the rice (Oryza sativa ssp indica) genome 14 3
117 1 117 2001 CHROMOSOMA 110(3):148-158
Pinsker W; Haring E; Hagemann S; Miller WJ
The evolutionary life history of P transposons: from horizontal invaders to domesticated neogenes 3 1
118 2 118 2001 CHROMOSOME RESEARCH 9(7):541-567
Cremer M; von Hase J; Volm T; Brero A; Kreth G; Walter J; Fischer C; Solovei I; Cremer C; Cremer T
Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells 18 4
119 2 119 2001 CHROMOSOME RESEARCH 9(7):569-584
Habermann FA; Cremer M; Walter J; Kreth G; von Hase J; Bauer K; Wienberg J; Cremer C; Cremer T; Solovei I
Arrangements of macro- and microchromosomes in chicken cells 13 3
120 1 120 2001 CIRCULATING NUCLEIC ACIDS IN PLASMA OR SERUM II 945():276-288
Doerfler W; Hohlweg U; Muller K; Remus R; Heller H; Hertz J
Foreign DNA integration - Perturbations of the genome - Oncogenesis 1 0
121 2 121 2001 CIRCULATION RESEARCH 89(6):547-554
Faber BCG; Cleutjens KBJM; Niessen RLJ; Aarts PLJW; Boon W; Greenberg AS; Kitslaar PJEHM; Tordoir JHM; Daemen MJAP
Identification of genes potentially involved in rupture of human atherosclerotic plaques 14 0
122 3 122 2001 CIRCULATION RESEARCH 89(11):1065-1072
Bang ML; Centner T; Fornoff F; Geach AJ; Gotthardt M; McNabb M; Witt CC; Labeit D; Gregorio CC; Granzier H; Labeit S
The complete gene sequence of titin, expression of an unusual approximate to 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system 30 2
123 2 123 2001 CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE 24(4):179-195
Scriver CR
Work, the clinician-scientist and human biochemical genetics 2 0
124 2 124 2001 CLINICAL CANCER RESEARCH 7(11):3416-3422
Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH
Single nucleotide polymorphisms in the human reduced folate carrier: Characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers 7 0
125 2 125 2001 CLINICAL CHEMISTRY 47(10):1931-1933
van Beuningen R; van Damme H; Boender P; Bastiaensen N; Chan A; Kievits T
Fast and specific hybridization using flow-through microarrays on porous metal oxide 1 0
126 1 126 2001 CLINICAL CHEMISTRY AND LABORATORY MEDICINE 39(12):1190-1194
Lan FH
Molecular diagnostics in China 0 0
127 2 127 2001 CLINICAL INFECTIOUS DISEASES 32(5):675-685
Fauci AS
Infectious diseases: Considerations for the 21st century 9 0
128 2 128 2001 CLINICAL PHARMACOKINETICS 40(12):907-946
Thorne RG; Frey WH
Delivery of neurotrophic factors to the central nervous system - Pharmacokinetic considerations 6 0
129 2 129 2001 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 66():313-320
Maquat LE; Serin G
Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins 1 0
130 3 130 2001 COMPARATIVE AND FUNCTIONAL GENOMICS 2(3):169-175
Simpson AJG; de Souza SJ; Camargo AA; Brentani RR
Definition of the gene content of the human genome: the need for deep experimental verification 0 0
131 3 131 2001 COMPUTERS & CHEMISTRY 25(4):313-315
Konopka AK
Towards understanding life itself 0 0
132 2 132 2001 COMPUTING IN SCIENCE & ENGINEERING 3(5):105-108
Lunney EA
Computing in drug discovery: The design phase 0 0
133 1 133 2001 CULTURE & PSYCHOLOGY 7(4):495-506
Moll I
Is the individual anything other than culture? 0 0
134 2 134 2001 CURRENT BIOLOGY 11(5):R155-R158
Koonin EV
Computational genomics 2 1
135 1 135 2001 CURRENT BIOLOGY 11(8):R296-R299
Wright S; Finnegan D
Genome evolution: Sex and the transposable element 6 0
136 3 136 2001 CURRENT BIOLOGY 11(8):R311-R314
Jackson IJ
Mouse genomics: Making sense of the sequence 0 0
137 2 137 2001 CURRENT BIOLOGY 11(11):R416-R417
Dawes H
Tapping into genome secrets 0 0
138 2 138 2001 CURRENT BIOLOGY 11(17):R680-R682
Harris T
Unfolding the genomes' structural secrets 0 0
139 8 139 2001 CURRENT BIOLOGY 11(20):R808-R811
Scherer SW; Cheung J
Discovery of the human genome sequence in the public and private databases 1 1
140 2 140 2001 CURRENT BIOLOGY 11(22):R900-R901
Brookfield JFY
Selection on Alu sequences? 3 3
141 1 141 2001 CURRENT BIOLOGY 11(19):1503-1511
Watters JW; Dewar K; Lehoczky J; Boyartchuk V; Dietrich WF
Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor 22 1
142 1 142 2001 CURRENT BIOLOGY 11(19):1531-1535
Turner G; Barbulescu M; Su M; Jensen-Seaman MI; Kidd KK; Lenz J
Insertional polymorphisms of full-length endogenous retroviruses in humans 14 7
143 2 143 2001 CURRENT GENETICS 40(3):157-171
Bill RM
Yeast - a panacea for the structure-function analysis of membrane proteins? 5 1
144 2 144 2001 CURRENT MEDICINAL CHEMISTRY 8(14):1713-1726
Buysse JM
The role of genomics in antibacterial target discovery 2 0
145 2 145 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(3):297-298
Zoon KC
Regulation of new biomedical technologies: the next frontier - Editorial overview 1 0
146 3 146 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):334-339
Xenarios L; Eisenberg D
Protein interaction databases 7 0
147 3 147 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):340-347
Pelletier J; Sidhu S
Mapping protein-protein interactions with combinatorial biology methods 4 1
148 2 148 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):348-354
Heinemann U; Illing G; Oschkinat H
High-throughput three-dimensional protein structure determination 12 0
149 2 149 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(5):483-487
Verrips CT; Warmoeskerken MMCG; Post JA
General introduction to the importance of genomics in food biotechnology and nutrition 6 0
150 2 150 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(5):516-522
Roberts MA; Mutch DM; German JB
Genomics: food and nutrition 6 2
151 3 151 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):607-612
Griffin TJ; Goodlett DR; Aebersold R
Advances in proteome analysis by mass spectrometry 8 1
152 4 152 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):622-625
Dean NM
Functional genomics and target validation approaches using antisense oligonucleotide technology 14 1
153 2 153 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):626-631
Walke DW; Han CS; Shaw J; Wann E; Zambrowicz B; Sands A
In vivo drug target discovery: identifying the best targets from the genome 5 3
154 3 154 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):632-637
Segal DJ; Barbas CF
Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins 7 2
155 2 155 2001 CURRENT OPINION IN CELL BIOLOGY 13(3):302-309
Hastings ML; Krainer AR
Pre-mRNA splicing in the new millennium 67 15
156 2 156 2001 CURRENT OPINION IN CELL BIOLOGY 13(5):611-618
Brummendorf T; Lemmon V
Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion 8 1
157 2 157 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):352-359
Whittaker PA
From symptomatic treatments to causative therapy? 1 0
158 1 158 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):416-423
Zhang ZY
Protein tyrosine phosphatases: prospects for therapeutics 39 7
159 2 159 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):464-470
Caron PR; Mullican MD; Mashal RD; Wilson KP; Su MS; Murcko MA
Chemogenomic approaches to drug discovery - Commentary 21 2
160 2 160 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):247-257
Sreekumar KR; Aravind L; Koonin EV
Computational analysis of human disease-associated genes and their protein products 8 5
161 1 161 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):268-273
Brown SDM; Balling R
Systematic approaches to mouse mutagenesis 25 3
162 2 162 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):612-615
Zavolan M; Kepler TB
Statistical inference of sequence-dependent mutation rates 5 0
163 5 163 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):616-619
Ochman H
Lateral and oblique gene transfer 1 0
164 4 164 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):627-634
Aquadro CF; DuMont VB; Reed FA
Genome-wide variation in the human and fruitfly: a comparison 5 0
165 2 165 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):652-659
Comeron JM
What controls the length of noncoding DNA? 7 0
166 3 166 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):673-680
Long M
Evolution of novel genes 20 8
167 4 167 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):681-684
Sankoff D
Gene and genome duplication 11 3
168 2 168 2001 CURRENT OPINION IN HEMATOLOGY 8(4):252-261
Golub TR
Genomic approaches to the pathogenesis of hematologic malignancy 1 1
169 2 169 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(3):229-234
Kole R; Sazani P
Antisense effects in the cell nucleus: Modification of splicing 17 2
170 6 170 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(6):533-537
Holmberg M; Lejon K
The identification and validation of common disease genes: Relevance to the drug development process 0 0
171 1 171 2001 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 10(5):655-659
Knepper MA; Brooks HL
Regulation of the sodium transporters NHE3, NKCC2 and NCC in the kidney 2 0
172 1 172 2001 CURRENT OPINION IN OBSTETRICS & GYNECOLOGY 13(3):309-314
Zondervan KT; Cardon LR; Kennedy SH
The genetic basis of endometriosis 9 0
173 4 173 2001 CURRENT OPINION IN PLANT BIOLOGY 4(6):478-487
Assaad FF
Of weeds and men: what genomes teach us about plant cell biology 6 0
174 3 174 2001 CURRENT SCIENCE 80(4):481-482
Balaram P
Publishing the genome 0 0
175 4 175 2001 CURRENT SCIENCE 81(5):515-522
Garrett MA
Cell cycle control and cancer 0 0
176 2 176 2001 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 62(11):803-819
Ardekani AM; Herman EH; Sistare FD; Liotta LA; Petricoin EF
Molecular profiling of cancer and drug-induced toxicity using new proteomic technologies 3 0
177 2 177 2001 DEFENCE SCIENCE JOURNAL 51(4):341-351
Pandit MW; Singh L
Human genome: A gift of 20(th) century and challenge for 21(st) century 0 0
178 2 178 2001 DEVELOPMENT GROWTH & DIFFERENTIATION 43(5):503-508
Ritzenthaler S; Chiba A
Multiple personalities: Synaptic target cells as introverts and extroverts 0 0
179 2 179 2001 DEVELOPMENTAL PSYCHOBIOLOGY 39(4):251-254
Roubertoux PL
Letter to the editor: Chronicle for an orphan trait: Comment on Hofer, Shair, Masmela, & Brunelli, "Developmental effects of selective breeding for an infantile trait: The rat pup ultrasonic isolation call" 0 0
180 1 180 2001 DISEASE MARKERS 17(2):67-75
Caballero OL; de Souza SJ; Brentani RR; Simpson AJG
Alternative spliced transcripts as cancer markers 5 1
181 3 181 2001 DISEASE MARKERS 17(2):89-98
Chanock S
Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease 10 2
182 1 182 2001 DNA AND CELL BIOLOGY 20(12):807-813
Yuan ZA; Chen EH; Gibson CW
Model system for evaluation of alternative splicing: Exon skipping 1 0
183 2 183 2001 DNA RESEARCH 8(2):85-95
Nagase T; Nakayama M; Nakajima D; Kikuno R; Ohara O
Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro 24 2
184 3 184 2001 DNA RESEARCH 8(4):179-187
Nagase T; Kikuno R; Ohara O
Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins 5 2
185 4 185 2001 DNA RESEARCH 8(6):319-327
Nagase T; Kikuno R; Ohara O
Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins 4 2
186 2 186 2001 DRUG DISCOVERY TODAY 6(15):S63-S64
Broder S; Venter JC
Genomics, science and medicine: the future is now 0 0
187 1 187 2001 DRUG DISCOVERY TODAY 6(15):S65-S66
Debouck CM
The genome: the beginning, not the end... and a means to many ends 0 0
188 2 188 2001 DRUG DISCOVERY TODAY 6(15):S72-S80
Freiberg C
Novel computational methods in anti-microbial target identification 5 0
189 1 189 2001 DRUG DISCOVERY TODAY 6(15):S81-S85
Wahlestedt C
Using genomics to understand the nervous system 0 0
190 1 190 2001 DRUG DISCOVERY TODAY 6(15):S91-S96
Nef P
Key animal models for the identification and validation of drug targets 0 0
191 2 191 2001 DRUG DISCOVERY TODAY 6(8):398-399
Szymkowski DE
Too many targets, not enough target validation 1 1
192 2 192 2001 DRUG DISCOVERY TODAY 6(12):621-627
Fruh K; Simmen K; Luukkonen BGM; Bell YC; Ghazal P
Virogenomics: a novel approach to antiviral drug discovery 6 0
193 1 193 2001 DRUG DISCOVERY TODAY 6(12):628-636
Harris S
Transgenic knockouts as part of high-throughput, evidence-based target selection and validation strategies 6 4
194 2 194 2001 DRUG DISCOVERY TODAY 6(13):665-666
Ilag LL
Too many targets, not enough target validation - Reply 0 0
195 1 195 2001 DRUG DISCOVERY TODAY 6(13):681-688
Southan C
A genomic perspective on human proteases as drug targets 11 2
196 1 196 2001 DRUG DISCOVERY TODAY 6(15):766-768
Gurwitz D; Weizman A
Animal models and human genome diversity: the pitfalls of inbred mice 4 1
197 3 197 2001 DRUG DISCOVERY TODAY 6(15):770-771
Sanseau P
Transgenic gene knockouts: a functional platform for the industry 0 0
198 2 198 2001 DRUG DISCOVERY TODAY 6(16):821-821
[Anon]
Human genome: bigger than we thought? 0 0
199 2 199 2001 DRUG DISCOVERY TODAY 6(17):881-+
Milburn J
Beyond the genome: turning data into knowledge 1 0
200 2 200 2001 DRUG DISCOVERY TODAY 6(19):996-1004
Maggio ET; Ramnarayan K
Recent developments in computational proteomics 6 2

# Cited
nodes Nodes / Authors GCS LCS
201 2 201 2001 DRUG DISCOVERY TODAY 6(23):1181-1182
Beck S
Genome acrobatics: understanding complex genomes 0 0
202 1 202 2001 DRUG DISCOVERY TODAY 6(24):1261-1262
Jhoti H
Structural genomics: lessons to be learnt 0 0
203 2 203 2001 ELECTROPHORESIS 22(19):4104-4117
Mitnik L; Novotny M; Felten C; Buonocore S; Koutny L; Schmalzing D
Recent advances in DNA sequencing by capillary and microdevice electrophoresis 6 1
204 1 204 2001 EMBO JOURNAL 20(17):4704-4716
Tutt A; Bertwistle D; Valentine J; Gabriel A; Swift S; Ross G; Griffin C; Thacker J; Ashworth A
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences 30 2
205 1 205 2001 EMBO JOURNAL 20(17):4987-4997
Le Hir H; Gatfield D; Izaurralde E; Moore MJ
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay 71 0
206 1 206 2001 EMBO JOURNAL 20(19):5354-5360
Betts MJ; Guigo R; Agarwal P; Russell RB
Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution? 10 4
207 2 207 2001 EMBO REPORTS 2(7):586-592
Cuadrado M; Sacristan M; Antequera F
Species-specific organization of CpG island promoters at mammalian homologous genes 4 1
208 1 208 2001 EMBO REPORTS 2(9):763-767
Bussolino F; Serini G; Mitola S; Bazzoni G; Dejana E
Dynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cells 2 0
209 4 209 2001 EMBO REPORTS 2(11):986-991
Mattick JS
Non-coding RNAs: the architects of eukaryotic complexity 26 4
210 1 210 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 38(2-3):209-215
Wilson MD; Ruttan CC; Koop BF; Glickman BW
ERCC1: A comparative genomic perspective 0 0
211 1 211 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(24):6435-6448
Titeux M; Brocheriou V; Xue ZG; Gao J; Pellissier JF; Guicheney P; Paulin D; Li ZL
Human synemin gene generates splice variants encoding two distinct intermediate filament proteins 7 2
212 2 212 2001 EUROPEAN JOURNAL OF CANCER 37():S119-S125
Trapman J
Molecular mechanisms of prostate cancer 1 0
213 2 213 2001 EUROPEAN JOURNAL OF CANCER 37(5):555-555
[Anon]
No new cancer genes found in human genome 0 0
214 1 214 2001 EUROPEAN JOURNAL OF HUMAN GENETICS 9(8):590-598
Vorechovsky I; Kralovicova J; Laycock MD; Webster ADB; Marsh SGE; Madrigal A; Hammarstrom L
Short tandem repeat (STR) haplotypes in HLA: an integrated 50- kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region 4 0
215 2 215 2001 EUROPEAN JOURNAL OF HUMAN GENETICS 9(9):659-666
West AB; Zimprich A; Lockhart PJ; Farrer M; Singleton A; Holtom B; Lincoln S; Hofer A; Hill L; Muller-Myhsok B; Wszolek ZK; Hardy J; Gasser T
Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes 5 0
216 2 216 2001 EUROPEAN JOURNAL OF IMMUNOLOGY 31(12):3469-3474
Liippo J; Nera KP; Veistinen E; Lahdesmaki A; Postila V; Kimby E; Riikonen P; Hammarstrom L; Pelkonen J; Lassila O
Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene 3 0
217 2 217 2001 EUROPEAN JOURNAL OF NEUROSCIENCE 14(5):769-776
Huber A
Scaffolding proteins organize multimolecular protein complexes for sensory signal transduction 8 0
218 2 218 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):431-439
Catalano M
Functionally gene-linked polymorphic regions and genetically controlled neurotransmitters metabolism 1 0
219 3 219 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):457-474
Lesch KP
Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs 3 0
220 3 220 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):491-499
Hurko O
Genetics and genomics in neuropsychopharmacology: the impact on drug discovery and development 0 0
221 2 221 2001 EUROPEAN RESPIRATORY JOURNAL 18(5):741-743
Hoidal JR
Genetics of COPD: present and future 4 0
222 2 222 2001 EUROPEAN RESPIRATORY JOURNAL 18(5):882-889
Bals R; Jany B
Identification of disease genes by expression profiling 1 0
223 2 223 2001 EXPERT OPINION ON BIOLOGICAL THERAPY 1(4):641-653
Masihi KN
Fighting infection using immunomodulatory agents 5 0
224 3 224 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(7):1327-1344
Sawyer T; Boyce B; Dalgarno D; Iuliucci J
Src inhibitors: genomics to therapeutics 7 2
225 2 225 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(7):1171-1203
Connell RD; Beebe JS
Patent focus on cancer chemotherapeutics. III Angiogenesis agents: October 2000-March 2001 3 0
226 2 226 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(11):1729-1752
Ilies MA; Balaban AT
Recent developments in cationic lipid-mediated gene delivery and gene therapy 5 1
227 3 227 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(12):1861-1887
Bailey WJ; Vanti WB; George SR; Blevins R; Swaminathan S; Bonini JA; Smith KE; Weinshank RL; O'Dowd BF
Patent status of the therapeutically important G-protein- coupled receptors 3 0
228 2 228 2001 FASEB JOURNAL 15(14):U112-U130
van Ruissen F; Jansen BJH; de Jongh GJ; van Vlijmen-Willems IMJJ; Schalkwijk J
Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries 0 0
229 2 229 2001 FASEB JOURNAL 15(12):U173-U196
Pisarchik A; Slominski AT
Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression 0 0
230 2 230 2001 FEBS LETTERS 498(2-3):214-218
Southan C
A genomic perspective on human proteases 10 1
231 2 231 2001 FEBS LETTERS 502(3):79-83
Yamaguchi J; Nemoto N; Sasaki T; Tokumasu A; Mimori-Kiyosue Y; Yagi T; Funatsu T
Rapid functional analysis of protein-protein interactions by fluorescent C-terminal labeling and single-molecule imaging 3 0
232 1 232 2001 FEBS LETTERS 504(3):112-117
Nollert P; Harries WEC; Fu DX; Miercke LJW; Stroud RM
Atomic structure of a glycerol channel and implications for substrate permeation in aqua(glycero)porins 10 0
233 1 233 2001 FEBS LETTERS 507(2):237-240
Montano X
Common amino acid sequence motifs in p53, 14-3-3 and Akt protein families 1 0
234 2 234 2001 FEBS LETTERS 507(3):264-268
Klussmann E; Edemir B; Pepperle B; Tamma G; Henn V; Klauschenz E; Hundsrucker C; Maric K; Rosenthal W
Ht31: The first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling 2 0
235 2 235 2001 FEBS LETTERS 508(1):143-148
Baranova AV; Lobashev AV; Ivanova DV; Krukovskaya LL; Yankovsky NK; Kozlov AP
In silico screening for tumour-specific expressed sequences in human genome 3 1
236 1 236 2001 FRONTIERS IN BIOSCIENCE 6():D866-D876
Filetici P; Ornaghi P; Ballario P
The bromodomain: A chromatin browser? 5 0
237 2 237 2001 FRONTIERS IN BIOSCIENCE 6():D904-D913
Martinez OP; Longman-Jacobsen N; Davies R; Chung EK; Yang Y; Gaudieri S; Dawkins RL; Yu CY
Genetics of human complement component C4 and evolution the central MHC 1 0
238 1 238 2001 GENE 270(1-2):17-30
Lecompte O; Thompson JD; Plewniak F; Thierry JC; Poch O
Multiple alignment of complete sequences (MACS) in the post- genomic era 7 0
239 1 239 2001 GENE 272(1-2):283-289
Amemiya CT; Amores A; Ota T; Mueller G; Garrity D; Postlethwait JH; Litman GW
Generation of a P1 artificial chromosome library of the Southern pufferfish 1 0
240 1 240 2001 GENE 273(1):51-61
Kurdyukov SG; Lebedev YB; Artamonova II; Gorodentseva TN; Batrak AV; Mamedov IZ; Azhikina TL; Legchilina SP; Efimenko IG; Gardiner K; Sverdlov ED
Full-sized HERV-K (HML-2) human endogenous retroviral LTR sequences on human chromosome 21: map locations and evolutionary history 6 2
241 2 241 2001 GENE 273(2):181-189
Pletcher MT; Nobukuni T; Fukuhara H; Kuramochi M; Maruyama T; Sekiya T; Sussan T; Isomura M; Murakami Y; Reeves RH
Identification of tumor suppressor candidate genes by physical and sequence mapping of the TSLC1 region of human chromosome 11q23 3 0
242 2 242 2001 GENE 274(1-2):245-252
Dear TN; Boehm T
Identification and characterization of two novel calpain large subunit genes 5 1
243 2 243 2001 GENE 275(1):31-37
Osada N; Hida M; Kususda J; Tanuma R; Iseki K; Hirata M; Suto Y; Hirai M; Terao K; Suzuki Y; Sugano S; Hashimoto K
Assignment of 118 novel cDNAs of cynomolgus monkey brain to human chromosomes 5 1
244 6 244 2001 GENE 276(1-2):3-13
Bernardi G
Misunderstandings about isochores. Part 1 14 12
245 4 245 2001 GENE 276(1-2):25-31
Clay O; Bernardi G
Compositional heterogeneity within and among isochores in mammalian genomes - II. Some general comments 7 5
246 1 246 2001 GENE 276(1-2):39-45
Pavlicek A; Jabbari K; Paces J; Paces V; Hejnar J; Bernardi G
Similar integration but different stability of Alus and LINEs in the human genome 9 9
247 2 247 2001 GENE 276(1-2):47-56
Oliver JL; Bernaola-Galvan P; Carpena P; Roman-Roldan R
Isochore chromosome maps of eukaryotic genomes 11 9
248 2 248 2001 GENE 276(1-2):57-72
Li WT
Delineating relative homogeneous G+C domains in DNA sequences 10 7
249 2 249 2001 GENE 276(1-2):73-81
Pesole G; Mignone F; Gissi C; Grillo G; Licciulli F; Liuni S
Structural and functional features of eukaryotic mRNA untranslated regions 14 4
250 2 250 2001 GENE 277(1-2):31-47
Goldstrohm AC; Greenleaf AL; Garcia-Blanco MA
Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing 16 2
251 2 251 2001 GENE 277(1-2):49-62
Sturm RA; Teasdale RD; Box NF
Human pigmentation genes: identification, structure and consequences of polymorphic variation 14 1
252 2 252 2001 GENE 278(1-2):41-51
Yuan TTT; Toy P; McClary JA; Lin RJ; Miyamoto NG; Kretschmer PJ
Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species 2 1
253 1 253 2001 GENE 278(1-2):63-79
Martin SC; Russek SJ; Farb DH
Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2 7 0
254 2 254 2001 GENE 280(1-2):175-181
Mujica AO; Hankeln T; Schmidt ER
A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3 3 0
255 2 255 2001 GENE 281(1-2):81-94
Smith AG; Box NF; Marks LH; Chen W; Smit DJ; Wyeth JR; Huttley GA; Easteal S; Sturm RA
The human melanocortin-1 receptor locus: analysis of transcription unit, locus polymorphism and haplotype evolution 1 0
256 1 256 2001 GENES CHROMOSOMES & CANCER 32(3):275-280
Milech N; Kees UR; Watt PM
Novel alternative PBX3 isoforms in leukemia cells with distinct interaction specificities 1 0
257 2 257 2001 GENETIC TESTING 5(4):275-280
Carroll AM; Coleman CH
Closing the gaps in genetics legislation and policy: A report by the New York State Task Force on Life and the Law 1 0
258 2 258 2001 GENETICA 111(1-3):3-23
Danzmann RG; Gharbi K
Gene mapping in fishes: a means to an end 1 1
259 1 259 2001 GENETICA 111(1-3):43-58
Devlin RH; Biagi CA; Smailus DE
Genetic mapping of Y-chromosomal DNA markers in Pacific salmon 5 1
260 2 260 2001 GENETICA 111(1-3):397-412
Sola L; Gornung E
Classical and molecular cytogenetics of the zebrafish, Danio rerio (Cyprinidae, Cypriniformes): an overview 1 0
261 1 261 2001 GENETICAL RESEARCH 78(2):121-136
Maside X; Bartolome C; Assimacopoulos S; Charlesworth B
Rates of movement and distribution of transposable elements in Drosophila melanogaster: in situ hybridization vs Southern blotting data 8 1
262 1 262 2001 GENETICS 158(2):735-746
Voss SR; Smith JJ; Gardiner DM; Parichy DM
Conserved vertebrate chromosome segments in the large salamander genome 4 1
263 1 263 2001 GENETICS 158(3):949-957
Rubin E; Lithwick G; Levy AA
Structure and evolution of the hAT transposon superfamily 5 2
264 2 264 2001 GENETICS 159(1):133-145
Fares H; Greenwald I
Genetic analysis of endocytosis in Caenorhabditis elegans: Coelomocyte uptake defective mutants 5 0
265 1 265 2001 GENETICS 159(1):279-290
Roy-Engel AM; Carroll ML; Vogel E; Garber RK; Nguyen SV; Salem AH; Batzer MA; Deininger PL
Alu insertion polymorphisms for the study of human genomic diversity 13 0
266 2 266 2001 GENETICS 159(2):441-452
Wloch DM; Szafraniec K; Borts RH; Korona R
Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae 8 0
267 1 267 2001 GENETICS 159(2):581-588
Noor MAF; Cunningham AL; Larkin JC
Consequences of recombination rate variation on quantitative trait locus mapping studies: Simulations based on the Drosophila melanogaster genome 9 1
268 2 268 2001 GENETICS 159(2):907-911
Galtier N; Piganeau G; Mouchiroud D; Duret L
GC-content evolution in mammalian genomes: The biased gene conversion hypothesis 13 6
269 1 269 2001 GENETICS 159(3):1151-1162
Ciobanu D; Bastiaansen J; Malek M; Helm J; Woollard J; Plastow G; Rothschild M
Evidence for new alleles in the protein kinase adenosine monophosphate-activated gamma(3)-subunit gene associated with low glycogen content in pig skeletal muscle and improved meat quality 12 0
270 1 270 2001 GENETICS 159(3):1191-1199
Urrutia AO; Hurst LD
Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection 9 2
271 1 271 2001 GENETICS IN MEDICINE 3(6):405-410
Yoon PW; Chen B; Faucett A; Clyne M; Gwinn M; Lubin IM; Burke W; Khoury MJ
Public health impact of genetic tests at the end of the 20th century 4 0
272 2 272 2001 GENETICS IN MEDICINE 3(6):426-429
McCabe ERB
Clinical genetics: Compassion, access, science, and advocacy 3 1
273 1

#	Cited nodes	Nodes / Authors	GCS	LCS
101	2	101 2001 CELL 106(4):391-394 Hastie ND Life, sex, and WT1 isoforms - Three amino acids can make all the difference	13	2
102	2	102 2001 CELL 106(4):413-415 Hogenesch JB; Ching KA; Batalov S; Su AI; Walker JR; Zhou YY; Kay SA; Schultz PG; Cooke MP A comparison of the Celera and Ensembl predicted gene sets reveals little overlap in novel genes	95	62
103	3	103 2001 CELL 106(5):619-632 Dong XZ; Han SK; Zylka MJ; Simon MI; Anderson DJ A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons	17	2
104	1	104 2001 CELL 107(1):13-16 Hamilton BA; Frankel WN Of mice and genome sequence	9	2
105	2	105 2001 CELL 107(2):195-207 Billuart P; Winter CG; Maresh A; Zhao XS; Luo LQ Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway	33	1
106	2	106 2001 CELL BIOCHEMISTRY AND BIOPHYSICS 35(1):35-47 Zhou HX; Wang GL Predicted structures of two proteins involved in human diseases	1	0
107	2	107 2001 CELLULAR AND MOLECULAR BIOLOGY 47(8):1301-1308 Guillouzo A Applications of biotechnology to pharmacology and toxicology	0	0
108	2	108 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(7):868-884 Jonsson AP Mass spectrometry for protein and peptide characterisation	12	1
109	2	109 2001 CELLULAR AND MOLECULAR LIFE SCIENCES 58(14):2085-2097 Li D; Roberts R WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases	7	0
110	2	110 2001 CHEMICAL INNOVATION 31(4):1-1 Block MJ Doing the genome thing	0	0
111	2	111 2001 CHEMICAL INNOVATION 31(6):29-32 Hutton S Back to biotech basics on the Internet	0	0
112	1	112 2001 CHEMICAL REVIEWS 101(8):2313-2340 Jackson MD; Denu JM Molecular reactions of protein phosphatases - Insights from structure and chemistry	14	1
113	2	113 2001 CHEMISTRY & BIOLOGY 8(10):931-939 Famulok M; Blind M; Mayer G Intramers as promising new tools in functional proteomics	13	0
114	2	114 2001 CHIMIA 55(6):487-492 Richmond TJ The structural basis of gene regulation for DNA organized as chromatin	0	0
115	2	115 2001 CHIMICA OGGI-CHEMISTRY TODAY 19(5):15-17 Stewart L; Moran S Advances in high-throughput crystallization	0	0
116	2	116 2001 CHINESE SCIENCE BULLETIN 46(23):1937-1942 Yu J; Hu SN; Wang J; Li SG; Wong KSG; Liu B; Deng Y; Dai L; Zhou Y; Zhang XQ; Cao ML; Liu J; Sun JD; Tang JB; Chen YJ; Huang XB; Lin W; Ye C; Tong W; Cong LJ; Geng JN; Han YJ; Li L; Li W; Hu GQ; Huang XG; Li WJ; Li J; Liu ZW; Li L; Liu JP; Qi QH; Liu JS; Li L; Wang XG; Lu H; Wu TT; Zhu M; Ni PX; Han H; Dong W; Ren XY; Feng XL; Cui P; Li XR; Wang H; Xu X; Zhai WX; Xu Z; Zhang JS; He SJ; Zhang JG; Xu JC; Zhang KL; Zheng XW; Dong JH; Zeng WY; Tao L; Chen XW; He J; Liu DF; Tian W; Tian CG; Xia HG; Li G; Gao H; Li P; Chen W; Wang XD; Zhang Y; Hu JF; Wang J; Liu S; Yang J; Zhang GY; Xiong YQ; Li ZJ; Mao L; Zhou CS; Zhu Z; Chen RS; Hao BL; Zheng WM; Chen SY; Guo W; Li GJ; Liu SQ; Huang GY; Tao M; Wang J; Zhu LH; Yuan LP; Yang HM A draft sequence of the rice (Oryza sativa ssp indica) genome	14	3
117	1	117 2001 CHROMOSOMA 110(3):148-158 Pinsker W; Haring E; Hagemann S; Miller WJ The evolutionary life history of P transposons: from horizontal invaders to domesticated neogenes	3	1
118	2	118 2001 CHROMOSOME RESEARCH 9(7):541-567 Cremer M; von Hase J; Volm T; Brero A; Kreth G; Walter J; Fischer C; Solovei I; Cremer C; Cremer T Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells	18	4
119	2	119 2001 CHROMOSOME RESEARCH 9(7):569-584 Habermann FA; Cremer M; Walter J; Kreth G; von Hase J; Bauer K; Wienberg J; Cremer C; Cremer T; Solovei I Arrangements of macro- and microchromosomes in chicken cells	13	3
120	1	120 2001 CIRCULATING NUCLEIC ACIDS IN PLASMA OR SERUM II 945():276-288 Doerfler W; Hohlweg U; Muller K; Remus R; Heller H; Hertz J Foreign DNA integration - Perturbations of the genome - Oncogenesis	1	0
121	2	121 2001 CIRCULATION RESEARCH 89(6):547-554 Faber BCG; Cleutjens KBJM; Niessen RLJ; Aarts PLJW; Boon W; Greenberg AS; Kitslaar PJEHM; Tordoir JHM; Daemen MJAP Identification of genes potentially involved in rupture of human atherosclerotic plaques	14	0
122	3	122 2001 CIRCULATION RESEARCH 89(11):1065-1072 Bang ML; Centner T; Fornoff F; Geach AJ; Gotthardt M; McNabb M; Witt CC; Labeit D; Gregorio CC; Granzier H; Labeit S The complete gene sequence of titin, expression of an unusual approximate to 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system	30	2
123	2	123 2001 CLINICAL AND INVESTIGATIVE MEDICINE-MEDECINE CLINIQUE ET EXPERIMENTALE 24(4):179-195 Scriver CR Work, the clinician-scientist and human biochemical genetics	2	0
124	2	124 2001 CLINICAL CANCER RESEARCH 7(11):3416-3422 Whetstine JR; Gifford AJ; Witt T; Liu XY; Flatley RM; Norris M; Haber M; Taub JW; Ravindranath Y; Matherly LH Single nucleotide polymorphisms in the human reduced folate carrier: Characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers	7	0
125	2	125 2001 CLINICAL CHEMISTRY 47(10):1931-1933 van Beuningen R; van Damme H; Boender P; Bastiaensen N; Chan A; Kievits T Fast and specific hybridization using flow-through microarrays on porous metal oxide	1	0
126	1	126 2001 CLINICAL CHEMISTRY AND LABORATORY MEDICINE 39(12):1190-1194 Lan FH Molecular diagnostics in China	0	0
127	2	127 2001 CLINICAL INFECTIOUS DISEASES 32(5):675-685 Fauci AS Infectious diseases: Considerations for the 21st century	9	0
128	2	128 2001 CLINICAL PHARMACOKINETICS 40(12):907-946 Thorne RG; Frey WH Delivery of neurotrophic factors to the central nervous system - Pharmacokinetic considerations	6	0
129	2	129 2001 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 66():313-320 Maquat LE; Serin G Nonsense-mediated mRNA decay: Insights into mechanism from the cellular abundance of human Upf1, Upf2, Upf3, and Upf3X proteins	1	0
130	3	130 2001 COMPARATIVE AND FUNCTIONAL GENOMICS 2(3):169-175 Simpson AJG; de Souza SJ; Camargo AA; Brentani RR Definition of the gene content of the human genome: the need for deep experimental verification	0	0
131	3	131 2001 COMPUTERS & CHEMISTRY 25(4):313-315 Konopka AK Towards understanding life itself	0	0
132	2	132 2001 COMPUTING IN SCIENCE & ENGINEERING 3(5):105-108 Lunney EA Computing in drug discovery: The design phase	0	0
133	1	133 2001 CULTURE & PSYCHOLOGY 7(4):495-506 Moll I Is the individual anything other than culture?	0	0
134	2	134 2001 CURRENT BIOLOGY 11(5):R155-R158 Koonin EV Computational genomics	2	1
135	1	135 2001 CURRENT BIOLOGY 11(8):R296-R299 Wright S; Finnegan D Genome evolution: Sex and the transposable element	6	0
136	3	136 2001 CURRENT BIOLOGY 11(8):R311-R314 Jackson IJ Mouse genomics: Making sense of the sequence	0	0
137	2	137 2001 CURRENT BIOLOGY 11(11):R416-R417 Dawes H Tapping into genome secrets	0	0
138	2	138 2001 CURRENT BIOLOGY 11(17):R680-R682 Harris T Unfolding the genomes' structural secrets	0	0
139	8	139 2001 CURRENT BIOLOGY 11(20):R808-R811 Scherer SW; Cheung J Discovery of the human genome sequence in the public and private databases	1	1
140	2	140 2001 CURRENT BIOLOGY 11(22):R900-R901 Brookfield JFY Selection on Alu sequences?	3	3
141	1	141 2001 CURRENT BIOLOGY 11(19):1503-1511 Watters JW; Dewar K; Lehoczky J; Boyartchuk V; Dietrich WF Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor	22	1
142	1	142 2001 CURRENT BIOLOGY 11(19):1531-1535 Turner G; Barbulescu M; Su M; Jensen-Seaman MI; Kidd KK; Lenz J Insertional polymorphisms of full-length endogenous retroviruses in humans	14	7
143	2	143 2001 CURRENT GENETICS 40(3):157-171 Bill RM Yeast - a panacea for the structure-function analysis of membrane proteins?	5	1
144	2	144 2001 CURRENT MEDICINAL CHEMISTRY 8(14):1713-1726 Buysse JM The role of genomics in antibacterial target discovery	2	0
145	2	145 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(3):297-298 Zoon KC Regulation of new biomedical technologies: the next frontier - Editorial overview	1	0
146	3	146 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):334-339 Xenarios L; Eisenberg D Protein interaction databases	7	0
147	3	147 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):340-347 Pelletier J; Sidhu S Mapping protein-protein interactions with combinatorial biology methods	4	1
148	2	148 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(4):348-354 Heinemann U; Illing G; Oschkinat H High-throughput three-dimensional protein structure determination	12	0
149	2	149 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(5):483-487 Verrips CT; Warmoeskerken MMCG; Post JA General introduction to the importance of genomics in food biotechnology and nutrition	6	0
150	2	150 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(5):516-522 Roberts MA; Mutch DM; German JB Genomics: food and nutrition	6	2
151	3	151 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):607-612 Griffin TJ; Goodlett DR; Aebersold R Advances in proteome analysis by mass spectrometry	8	1
152	4	152 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):622-625 Dean NM Functional genomics and target validation approaches using antisense oligonucleotide technology	14	1
153	2	153 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):626-631 Walke DW; Han CS; Shaw J; Wann E; Zambrowicz B; Sands A In vivo drug target discovery: identifying the best targets from the genome	5	3
154	3	154 2001 CURRENT OPINION IN BIOTECHNOLOGY 12(6):632-637 Segal DJ; Barbas CF Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins	7	2
155	2	155 2001 CURRENT OPINION IN CELL BIOLOGY 13(3):302-309 Hastings ML; Krainer AR Pre-mRNA splicing in the new millennium	67	15
156	2	156 2001 CURRENT OPINION IN CELL BIOLOGY 13(5):611-618 Brummendorf T; Lemmon V Immunoglobulin superfamily receptors: cis-interactions, intracellular adapters and alternative splicing regulate adhesion	8	1
157	2	157 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):352-359 Whittaker PA From symptomatic treatments to causative therapy?	1	0
158	1	158 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):416-423 Zhang ZY Protein tyrosine phosphatases: prospects for therapeutics	39	7
159	2	159 2001 CURRENT OPINION IN CHEMICAL BIOLOGY 5(4):464-470 Caron PR; Mullican MD; Mashal RD; Wilson KP; Su MS; Murcko MA Chemogenomic approaches to drug discovery - Commentary	21	2
160	2	160 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):247-257 Sreekumar KR; Aravind L; Koonin EV Computational analysis of human disease-associated genes and their protein products	8	5
161	1	161 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(3):268-273 Brown SDM; Balling R Systematic approaches to mouse mutagenesis	25	3
162	2	162 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):612-615 Zavolan M; Kepler TB Statistical inference of sequence-dependent mutation rates	5	0
163	5	163 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):616-619 Ochman H Lateral and oblique gene transfer	1	0
164	4	164 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):627-634 Aquadro CF; DuMont VB; Reed FA Genome-wide variation in the human and fruitfly: a comparison	5	0
165	2	165 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):652-659 Comeron JM What controls the length of noncoding DNA?	7	0
166	3	166 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):673-680 Long M Evolution of novel genes	20	8
167	4	167 2001 CURRENT OPINION IN GENETICS & DEVELOPMENT 11(6):681-684 Sankoff D Gene and genome duplication	11	3
168	2	168 2001 CURRENT OPINION IN HEMATOLOGY 8(4):252-261 Golub TR Genomic approaches to the pathogenesis of hematologic malignancy	1	1
169	2	169 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(3):229-234 Kole R; Sazani P Antisense effects in the cell nucleus: Modification of splicing	17	2
170	6	170 2001 CURRENT OPINION IN MOLECULAR THERAPEUTICS 3(6):533-537 Holmberg M; Lejon K The identification and validation of common disease genes: Relevance to the drug development process	0	0
171	1	171 2001 CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION 10(5):655-659 Knepper MA; Brooks HL Regulation of the sodium transporters NHE3, NKCC2 and NCC in the kidney	2	0
172	1	172 2001 CURRENT OPINION IN OBSTETRICS & GYNECOLOGY 13(3):309-314 Zondervan KT; Cardon LR; Kennedy SH The genetic basis of endometriosis	9	0
173	4	173 2001 CURRENT OPINION IN PLANT BIOLOGY 4(6):478-487 Assaad FF Of weeds and men: what genomes teach us about plant cell biology	6	0
174	3	174 2001 CURRENT SCIENCE 80(4):481-482 Balaram P Publishing the genome	0	0
175	4	175 2001 CURRENT SCIENCE 81(5):515-522 Garrett MA Cell cycle control and cancer	0	0
176	2	176 2001 CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL 62(11):803-819 Ardekani AM; Herman EH; Sistare FD; Liotta LA; Petricoin EF Molecular profiling of cancer and drug-induced toxicity using new proteomic technologies	3	0
177	2	177 2001 DEFENCE SCIENCE JOURNAL 51(4):341-351 Pandit MW; Singh L Human genome: A gift of 20(th) century and challenge for 21(st) century	0	0
178	2	178 2001 DEVELOPMENT GROWTH & DIFFERENTIATION 43(5):503-508 Ritzenthaler S; Chiba A Multiple personalities: Synaptic target cells as introverts and extroverts	0	0
179	2	179 2001 DEVELOPMENTAL PSYCHOBIOLOGY 39(4):251-254 Roubertoux PL Letter to the editor: Chronicle for an orphan trait: Comment on Hofer, Shair, Masmela, & Brunelli, "Developmental effects of selective breeding for an infantile trait: The rat pup ultrasonic isolation call"	0	0
180	1	180 2001 DISEASE MARKERS 17(2):67-75 Caballero OL; de Souza SJ; Brentani RR; Simpson AJG Alternative spliced transcripts as cancer markers	5	1
181	3	181 2001 DISEASE MARKERS 17(2):89-98 Chanock S Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease	10	2
182	1	182 2001 DNA AND CELL BIOLOGY 20(12):807-813 Yuan ZA; Chen EH; Gibson CW Model system for evaluation of alternative splicing: Exon skipping	1	0
183	2	183 2001 DNA RESEARCH 8(2):85-95 Nagase T; Nakayama M; Nakajima D; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro	24	2
184	3	184 2001 DNA RESEARCH 8(4):179-187 Nagase T; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins	5	2
185	4	185 2001 DNA RESEARCH 8(6):319-327 Nagase T; Kikuno R; Ohara O Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins	4	2
186	2	186 2001 DRUG DISCOVERY TODAY 6(15):S63-S64 Broder S; Venter JC Genomics, science and medicine: the future is now	0	0
187	1	187 2001 DRUG DISCOVERY TODAY 6(15):S65-S66 Debouck CM The genome: the beginning, not the end... and a means to many ends	0	0
188	2	188 2001 DRUG DISCOVERY TODAY 6(15):S72-S80 Freiberg C Novel computational methods in anti-microbial target identification	5	0
189	1	189 2001 DRUG DISCOVERY TODAY 6(15):S81-S85 Wahlestedt C Using genomics to understand the nervous system	0	0
190	1	190 2001 DRUG DISCOVERY TODAY 6(15):S91-S96 Nef P Key animal models for the identification and validation of drug targets	0	0
191	2	191 2001 DRUG DISCOVERY TODAY 6(8):398-399 Szymkowski DE Too many targets, not enough target validation	1	1
192	2	192 2001 DRUG DISCOVERY TODAY 6(12):621-627 Fruh K; Simmen K; Luukkonen BGM; Bell YC; Ghazal P Virogenomics: a novel approach to antiviral drug discovery	6	0
193	1	193 2001 DRUG DISCOVERY TODAY 6(12):628-636 Harris S Transgenic knockouts as part of high-throughput, evidence-based target selection and validation strategies	6	4
194	2	194 2001 DRUG DISCOVERY TODAY 6(13):665-666 Ilag LL Too many targets, not enough target validation - Reply	0	0
195	1	195 2001 DRUG DISCOVERY TODAY 6(13):681-688 Southan C A genomic perspective on human proteases as drug targets	11	2
196	1	196 2001 DRUG DISCOVERY TODAY 6(15):766-768 Gurwitz D; Weizman A Animal models and human genome diversity: the pitfalls of inbred mice	4	1
197	3	197 2001 DRUG DISCOVERY TODAY 6(15):770-771 Sanseau P Transgenic gene knockouts: a functional platform for the industry	0	0
198	2	198 2001 DRUG DISCOVERY TODAY 6(16):821-821 [Anon] Human genome: bigger than we thought?	0	0
199	2	199 2001 DRUG DISCOVERY TODAY 6(17):881-+ Milburn J Beyond the genome: turning data into knowledge	1	0
200	2	200 2001 DRUG DISCOVERY TODAY 6(19):996-1004 Maggio ET; Ramnarayan K Recent developments in computational proteomics	6	2

#	Cited nodes	Nodes / Authors	GCS	LCS
201	2	201 2001 DRUG DISCOVERY TODAY 6(23):1181-1182 Beck S Genome acrobatics: understanding complex genomes	0	0
202	1	202 2001 DRUG DISCOVERY TODAY 6(24):1261-1262 Jhoti H Structural genomics: lessons to be learnt	0	0
203	2	203 2001 ELECTROPHORESIS 22(19):4104-4117 Mitnik L; Novotny M; Felten C; Buonocore S; Koutny L; Schmalzing D Recent advances in DNA sequencing by capillary and microdevice electrophoresis	6	1
204	1	204 2001 EMBO JOURNAL 20(17):4704-4716 Tutt A; Bertwistle D; Valentine J; Gabriel A; Swift S; Ross G; Griffin C; Thacker J; Ashworth A Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences	30	2
205	1	205 2001 EMBO JOURNAL 20(17):4987-4997 Le Hir H; Gatfield D; Izaurralde E; Moore MJ The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay	71	0
206	1	206 2001 EMBO JOURNAL 20(19):5354-5360 Betts MJ; Guigo R; Agarwal P; Russell RB Exon structure conservation despite low sequence similarity: a relic of dramatic events in evolution?	10	4
207	2	207 2001 EMBO REPORTS 2(7):586-592 Cuadrado M; Sacristan M; Antequera F Species-specific organization of CpG island promoters at mammalian homologous genes	4	1
208	1	208 2001 EMBO REPORTS 2(9):763-767 Bussolino F; Serini G; Mitola S; Bazzoni G; Dejana E Dynamic modules and heterogeneity of function: a lesson from tyrosine kinase receptors in endothelial cells	2	0
209	4	209 2001 EMBO REPORTS 2(11):986-991 Mattick JS Non-coding RNAs: the architects of eukaryotic complexity	26	4
210	1	210 2001 ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 38(2-3):209-215 Wilson MD; Ruttan CC; Koop BF; Glickman BW ERCC1: A comparative genomic perspective	0	0
211	1	211 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(24):6435-6448 Titeux M; Brocheriou V; Xue ZG; Gao J; Pellissier JF; Guicheney P; Paulin D; Li ZL Human synemin gene generates splice variants encoding two distinct intermediate filament proteins	7	2
212	2	212 2001 EUROPEAN JOURNAL OF CANCER 37():S119-S125 Trapman J Molecular mechanisms of prostate cancer	1	0
213	2	213 2001 EUROPEAN JOURNAL OF CANCER 37(5):555-555 [Anon] No new cancer genes found in human genome	0	0
214	1	214 2001 EUROPEAN JOURNAL OF HUMAN GENETICS 9(8):590-598 Vorechovsky I; Kralovicova J; Laycock MD; Webster ADB; Marsh SGE; Madrigal A; Hammarstrom L Short tandem repeat (STR) haplotypes in HLA: an integrated 50- kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region	4	0
215	2	215 2001 EUROPEAN JOURNAL OF HUMAN GENETICS 9(9):659-666 West AB; Zimprich A; Lockhart PJ; Farrer M; Singleton A; Holtom B; Lincoln S; Hofer A; Hill L; Muller-Myhsok B; Wszolek ZK; Hardy J; Gasser T Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes	5	0
216	2	216 2001 EUROPEAN JOURNAL OF IMMUNOLOGY 31(12):3469-3474 Liippo J; Nera KP; Veistinen E; Lahdesmaki A; Postila V; Kimby E; Riikonen P; Hammarstrom L; Pelkonen J; Lassila O Both normal and leukemic B lymphocytes express multiple isoforms of the human Aiolos gene	3	0
217	2	217 2001 EUROPEAN JOURNAL OF NEUROSCIENCE 14(5):769-776 Huber A Scaffolding proteins organize multimolecular protein complexes for sensory signal transduction	8	0
218	2	218 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):431-439 Catalano M Functionally gene-linked polymorphic regions and genetically controlled neurotransmitters metabolism	1	0
219	3	219 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):457-474 Lesch KP Variation of serotonergic gene expression: neurodevelopment and the complexity of response to psychopharmacologic drugs	3	0
220	3	220 2001 EUROPEAN NEUROPSYCHOPHARMACOLOGY 11(6):491-499 Hurko O Genetics and genomics in neuropsychopharmacology: the impact on drug discovery and development	0	0
221	2	221 2001 EUROPEAN RESPIRATORY JOURNAL 18(5):741-743 Hoidal JR Genetics of COPD: present and future	4	0
222	2	222 2001 EUROPEAN RESPIRATORY JOURNAL 18(5):882-889 Bals R; Jany B Identification of disease genes by expression profiling	1	0
223	2	223 2001 EXPERT OPINION ON BIOLOGICAL THERAPY 1(4):641-653 Masihi KN Fighting infection using immunomodulatory agents	5	0
224	3	224 2001 EXPERT OPINION ON INVESTIGATIONAL DRUGS 10(7):1327-1344 Sawyer T; Boyce B; Dalgarno D; Iuliucci J Src inhibitors: genomics to therapeutics	7	2
225	2	225 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(7):1171-1203 Connell RD; Beebe JS Patent focus on cancer chemotherapeutics. III Angiogenesis agents: October 2000-March 2001	3	0
226	2	226 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(11):1729-1752 Ilies MA; Balaban AT Recent developments in cationic lipid-mediated gene delivery and gene therapy	5	1
227	3	227 2001 EXPERT OPINION ON THERAPEUTIC PATENTS 11(12):1861-1887 Bailey WJ; Vanti WB; George SR; Blevins R; Swaminathan S; Bonini JA; Smith KE; Weinshank RL; O'Dowd BF Patent status of the therapeutically important G-protein- coupled receptors	3	0
228	2	228 2001 FASEB JOURNAL 15(14):U112-U130 van Ruissen F; Jansen BJH; de Jongh GJ; van Vlijmen-Willems IMJJ; Schalkwijk J Differential gene expression in premalignant human epidermis revealed by cluster analysis of serial analysis of gene expression (SAGE) libraries	0	0
229	2	229 2001 FASEB JOURNAL 15(12):U173-U196 Pisarchik A; Slominski AT Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression	0	0
230	2	230 2001 FEBS LETTERS 498(2-3):214-218 Southan C A genomic perspective on human proteases	10	1
231	2	231 2001 FEBS LETTERS 502(3):79-83 Yamaguchi J; Nemoto N; Sasaki T; Tokumasu A; Mimori-Kiyosue Y; Yagi T; Funatsu T Rapid functional analysis of protein-protein interactions by fluorescent C-terminal labeling and single-molecule imaging	3	0
232	1	232 2001 FEBS LETTERS 504(3):112-117 Nollert P; Harries WEC; Fu DX; Miercke LJW; Stroud RM Atomic structure of a glycerol channel and implications for substrate permeation in aqua(glycero)porins	10	0
233	1	233 2001 FEBS LETTERS 507(2):237-240 Montano X Common amino acid sequence motifs in p53, 14-3-3 and Akt protein families	1	0
234	2	234 2001 FEBS LETTERS 507(3):264-268 Klussmann E; Edemir B; Pepperle B; Tamma G; Henn V; Klauschenz E; Hundsrucker C; Maric K; Rosenthal W Ht31: The first protein kinase A anchoring protein to integrate protein kinase A and Rho signaling	2	0
235	2	235 2001 FEBS LETTERS 508(1):143-148 Baranova AV; Lobashev AV; Ivanova DV; Krukovskaya LL; Yankovsky NK; Kozlov AP In silico screening for tumour-specific expressed sequences in human genome	3	1
236	1	236 2001 FRONTIERS IN BIOSCIENCE 6():D866-D876 Filetici P; Ornaghi P; Ballario P The bromodomain: A chromatin browser?	5	0
237	2	237 2001 FRONTIERS IN BIOSCIENCE 6():D904-D913 Martinez OP; Longman-Jacobsen N; Davies R; Chung EK; Yang Y; Gaudieri S; Dawkins RL; Yu CY Genetics of human complement component C4 and evolution the central MHC	1	0
238	1	238 2001 GENE 270(1-2):17-30 Lecompte O; Thompson JD; Plewniak F; Thierry JC; Poch O Multiple alignment of complete sequences (MACS) in the post- genomic era	7	0
239	1	239 2001 GENE 272(1-2):283-289 Amemiya CT; Amores A; Ota T; Mueller G; Garrity D; Postlethwait JH; Litman GW Generation of a P1 artificial chromosome library of the Southern pufferfish	1	0
240	1	240 2001 GENE 273(1):51-61 Kurdyukov SG; Lebedev YB; Artamonova II; Gorodentseva TN; Batrak AV; Mamedov IZ; Azhikina TL; Legchilina SP; Efimenko IG; Gardiner K; Sverdlov ED Full-sized HERV-K (HML-2) human endogenous retroviral LTR sequences on human chromosome 21: map locations and evolutionary history	6	2
241	2	241 2001 GENE 273(2):181-189 Pletcher MT; Nobukuni T; Fukuhara H; Kuramochi M; Maruyama T; Sekiya T; Sussan T; Isomura M; Murakami Y; Reeves RH Identification of tumor suppressor candidate genes by physical and sequence mapping of the TSLC1 region of human chromosome 11q23	3	0
242	2	242 2001 GENE 274(1-2):245-252 Dear TN; Boehm T Identification and characterization of two novel calpain large subunit genes	5	1
243	2	243 2001 GENE 275(1):31-37 Osada N; Hida M; Kususda J; Tanuma R; Iseki K; Hirata M; Suto Y; Hirai M; Terao K; Suzuki Y; Sugano S; Hashimoto K Assignment of 118 novel cDNAs of cynomolgus monkey brain to human chromosomes	5	1
244	6	244 2001 GENE 276(1-2):3-13 Bernardi G Misunderstandings about isochores. Part 1	14	12
245	4	245 2001 GENE 276(1-2):25-31 Clay O; Bernardi G Compositional heterogeneity within and among isochores in mammalian genomes - II. Some general comments	7	5
246	1	246 2001 GENE 276(1-2):39-45 Pavlicek A; Jabbari K; Paces J; Paces V; Hejnar J; Bernardi G Similar integration but different stability of Alus and LINEs in the human genome	9	9
247	2	247 2001 GENE 276(1-2):47-56 Oliver JL; Bernaola-Galvan P; Carpena P; Roman-Roldan R Isochore chromosome maps of eukaryotic genomes	11	9
248	2	248 2001 GENE 276(1-2):57-72 Li WT Delineating relative homogeneous G+C domains in DNA sequences	10	7
249	2	249 2001 GENE 276(1-2):73-81 Pesole G; Mignone F; Gissi C; Grillo G; Licciulli F; Liuni S Structural and functional features of eukaryotic mRNA untranslated regions	14	4
250	2	250 2001 GENE 277(1-2):31-47 Goldstrohm AC; Greenleaf AL; Garcia-Blanco MA Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing	16	2
251	2	251 2001 GENE 277(1-2):49-62 Sturm RA; Teasdale RD; Box NF Human pigmentation genes: identification, structure and consequences of polymorphic variation	14	1
252	2	252 2001 GENE 278(1-2):41-51 Yuan TTT; Toy P; McClary JA; Lin RJ; Miyamoto NG; Kretschmer PJ Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species	2	1
253	1	253 2001 GENE 278(1-2):63-79 Martin SC; Russek SJ; Farb DH Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2	7	0
254	2	254 2001 GENE 280(1-2):175-181 Mujica AO; Hankeln T; Schmidt ER A novel serine/threonine kinase gene, STK33, on human chromosome 11p15.3	3	0
255	2	255 2001 GENE 281(1-2):81-94 Smith AG; Box NF; Marks LH; Chen W; Smit DJ; Wyeth JR; Huttley GA; Easteal S; Sturm RA The human melanocortin-1 receptor locus: analysis of transcription unit, locus polymorphism and haplotype evolution	1	0
256	1	256 2001 GENES CHROMOSOMES & CANCER 32(3):275-280 Milech N; Kees UR; Watt PM Novel alternative PBX3 isoforms in leukemia cells with distinct interaction specificities	1	0
257	2	257 2001 GENETIC TESTING 5(4):275-280 Carroll AM; Coleman CH Closing the gaps in genetics legislation and policy: A report by the New York State Task Force on Life and the Law	1	0
258	2	258 2001 GENETICA 111(1-3):3-23 Danzmann RG; Gharbi K Gene mapping in fishes: a means to an end	1	1
259	1	259 2001 GENETICA 111(1-3):43-58 Devlin RH; Biagi CA; Smailus DE Genetic mapping of Y-chromosomal DNA markers in Pacific salmon	5	1
260	2	260 2001 GENETICA 111(1-3):397-412 Sola L; Gornung E Classical and molecular cytogenetics of the zebrafish, Danio rerio (Cyprinidae, Cypriniformes): an overview	1	0
261	1	261 2001 GENETICAL RESEARCH 78(2):121-136 Maside X; Bartolome C; Assimacopoulos S; Charlesworth B Rates of movement and distribution of transposable elements in Drosophila melanogaster: in situ hybridization vs Southern blotting data	8	1
262	1	262 2001 GENETICS 158(2):735-746 Voss SR; Smith JJ; Gardiner DM; Parichy DM Conserved vertebrate chromosome segments in the large salamander genome	4	1
263	1	263 2001 GENETICS 158(3):949-957 Rubin E; Lithwick G; Levy AA Structure and evolution of the hAT transposon superfamily	5	2
264	2	264 2001 GENETICS 159(1):133-145 Fares H; Greenwald I Genetic analysis of endocytosis in Caenorhabditis elegans: Coelomocyte uptake defective mutants	5	0
265	1	265 2001 GENETICS 159(1):279-290 Roy-Engel AM; Carroll ML; Vogel E; Garber RK; Nguyen SV; Salem AH; Batzer MA; Deininger PL Alu insertion polymorphisms for the study of human genomic diversity	13	0
266	2	266 2001 GENETICS 159(2):441-452 Wloch DM; Szafraniec K; Borts RH; Korona R Direct estimate of the mutation rate and the distribution of fitness effects in the yeast Saccharomyces cerevisiae	8	0
267	1	267 2001 GENETICS 159(2):581-588 Noor MAF; Cunningham AL; Larkin JC Consequences of recombination rate variation on quantitative trait locus mapping studies: Simulations based on the Drosophila melanogaster genome	9	1
268	2	268 2001 GENETICS 159(2):907-911 Galtier N; Piganeau G; Mouchiroud D; Duret L GC-content evolution in mammalian genomes: The biased gene conversion hypothesis	13	6
269	1	269 2001 GENETICS 159(3):1151-1162 Ciobanu D; Bastiaansen J; Malek M; Helm J; Woollard J; Plastow G; Rothschild M Evidence for new alleles in the protein kinase adenosine monophosphate-activated gamma(3)-subunit gene associated with low glycogen content in pig skeletal muscle and improved meat quality	12	0
270	1	270 2001 GENETICS 159(3):1191-1199 Urrutia AO; Hurst LD Codon usage bias covaries with expression breadth and the rate of synonymous evolution in humans, but this is not evidence for selection	9	2
271	1	271 2001 GENETICS IN MEDICINE 3(6):405-410 Yoon PW; Chen B; Faucett A; Clyne M; Gwinn M; Lubin IM; Burke W; Khoury MJ Public health impact of genetic tests at the end of the 20th century	4	0
272	2	272 2001 GENETICS IN MEDICINE 3(6):426-429 McCabe ERB Clinical genetics: Compassion, access, science, and advocacy	3	1
273	1