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Tue Aug 31 16:33:13 2004
Naturally secreted oligomers of amyloid beta protein potently
inhibit hippocampal long-term potentiation in vivo

Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R,
Wolfe MS, Rowan MJ, Selkoe DJ
NATURE 416 (6880): 535-539 APR 4 2002
and the citing papers

Nodes: 246
Authors: 958, Journals: 112, Outer References: 9412
Collection span: 2002 - 2004
View: Overview. Sorted by GCS.
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#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
201330184 2004 BIOPHYSICAL JOURNAL 86(6):3585-3597
Mobley DL; Cox DL; Singh RRP; Maddox MW; Longo ML
Modeling amyloid beta-peptide insertion into lipid bilayers
00
202586185 2004 BIOPOLYMERS 76(1):4-14
Bateman DA; Chakrabartty A
Interactions of Alzheimer amyloid peptides with cultured cells and brain tissue, and their biological consequences
00
203153187 2004 BRAIN RESEARCH 998(1):73-82
Kasa P; Papp H; Kasa P; Pakaski M; Balaspiri L
Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain
00
2046278190 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(14):1729-1750
Bonifati V; Oostra BA; Heutink P
Unraveling the pathogenesis of Parkinson's disease - the contribution of monogenic forms
00
2051158192 2004 EUROPEAN JOURNAL OF NEUROSCIENCE 19(10):2839-2846
Klyubin I; Walsh DM; Cullen WK; Fadeeva JV; Anwyl R; Selkoe DJ; Rowan MJ
Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo
00
206179193 2004 EXPERIMENTAL NEUROLOGY 188(2):224-237
Wen PH; Hof PR; Chen XP; Gluck K; Austin G; Younkin SG; Younkin LH; DeGasperi R; Sosa MAG; Robakis NK; Haroutunian V; Elder GA
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
00
207542194 2004 FASEB JOURNAL 18(10)
Barnham KJ; Haeffner F; Ciccotosto GD; Curtain CC; Tew D; Mavros C; Beyreuther K; Carrington D; Masters CL; Cherny RA; Cappai R; Bush AI
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid
00
208221195 2004 HISTOLOGY AND HISTOPATHOLOGY 19(3):845-852
Fukuchi K; Hart M; Yan Z; Hassell JR; Li L
Transgenic mice overexpressing both amyloid B-protein and perlecan in pancreatic acinar cells
00
209161196 2004 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36(10):2066-2076
Clementi ME; Martorana GE; Pezzotti M; Giardina B; Misiti F
Methionine 35 oxidation reduces toxic effects of the amyloid beta-protein fragment (31-35) on human red blood cell
00
210140197 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(13):12206-12212
Green JD; Goldsbury C; Kistler J; Cooper GJS; Aebi U
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
211373198 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(13):13183-13189
Sirangelo I; Malmo C; Iannuzzi C; Mezzogiorno A; Bianco MR; Papa M; Irace G
Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F
00
212356199 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(14):14111-14119
Plakoutsi G; Taddei N; Stefani M; Chiti F
Aggregation of the acylphosphatase from Sulfolobus solfataricus - The folded and partially unfolded states can both be precursors for amyloid formation
00
213153200 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(15):14673-14678
Nagano S; Huang XD; Moir RD; Payton SM; Tanzi RE; Bush AI
Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links beta-amyloid (A beta) and generates A beta-COX-2 hetero-oligomers that are increased in Alzheimer's disease
00
214358202 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(30):31374-31382
Bucciantini M; Calloni G; Chiti F; Formigli L; Nosi D; Dobson CM; Stefani M
Prefibrillar amyloid protein aggregates share common features of cytotoxicity
00
215665203 2004 JOURNAL OF CHEMICAL PHYSICS 120(12):5809-5823
Friedel M; Shea JE
Self-assembly of peptides into a beta-barrel motif
00
216228204 2004 JOURNAL OF CHEMICAL PHYSICS 120(17):8307-8317
Tiana G; Simona F; Brogliaa RA; Colombo G
Thermodynamics of beta-amyloid fibril formation
00
217527206 2004 JOURNAL OF MEDICINAL CHEMISTRY 47(13):3329-3333
Wang ZQ; Chang L; Klein WL; Thatcher GRJ; Venton DL
Per-6-substituted-per-6-deoxy beta-cyclodextrins inhibit the formation of beta-amyloid peptide derived soluble oligomers
00
218142207 2004 JOURNAL OF MOLECULAR BIOLOGY 336(3):775-786
Hall D; Edskes H
Silent prions lying in wait: A two-hit model of prion/amyloid formation and infection
00
219459208 2004 JOURNAL OF MOLECULAR BIOLOGY 338(5):943-957
Gliozzi A; Rosano C; Canale C; Bolognesi M; Plakoutsi G; Bucciantini M; Chiti F; Stefani M
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils
00
220481210 2004 JOURNAL OF MOLECULAR NEUROSCIENCE 23(3):235-246
Manelli AM; Stine WB; Van Eldik LJ; Ladu MJ
ApoE and A beta 1-42 interactions
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
221123211 2004 JOURNAL OF NEUROCHEMISTRY 88(2):281-290
Gibson G; Gunasekera N; Lee M; Lelyveld V; El-Agnaf OMA; Wright A; Austen B
Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia
00
222332212 2004 JOURNAL OF NEUROCHEMISTRY 89(4):807-811
Zlokovic BV
Clearing amyloid through the blood-brain barrier
00
223127213 2004 JOURNAL OF NEUROCHEMISTRY 89(6):1409-1416
Chang WP; Koelsch G; Wong S; Downs D; Da HN; Weerasena V; Gordon B; Devasamudram T; Bilcer G; Ghosh AK; Tang J
In vivo inhibition of A beta production by memapsin 2 (beta-secretase) inhibitors
00
224263214 2004 JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 63(3):255-261
Takuma H; Tomiyama T; Kuida K; Mori H
Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo
00
225786216 2004 JOURNAL OF NEUROSCIENCE 24(11):2716-2726
Lin H; Zhai JB; Canete-Soler R; Schlaepfer WW
3 ' untranslated region in a light neurofilament (NF-L) mRNA triggers aggregation of NF-L and mutant superoxide dismutase 1 proteins in neuronal cells
00
226252218 2004 JOURNAL OF NEUROSCIENCE 24(13):3444-3452
Suo ZM; Wu M; Citron BA; Wong GT; Festoff BW
Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimer's disease: An association with early beta-amyloid accumulation
00
227340219 2004 JOURNAL OF NEUROSCIENCE 24(16):3899-3906
Greeve I; Kretzschmar D; Tschape JA; Beyn A; Brellinger C; Schweizer M; Nitsch RM; Reifegerste R
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
00
228448220 2004 JOURNAL OF NEUROSCIENCE 24(19):4535-4540
Stern EA; Bacskai BJ; Hickey GA; Attenello FJ; Lombardo JA; Hyman BT
Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques
00
229554221 2004 JOURNAL OF NEUROSCIENCE 24(27):6049-6056
Wang QW; Rowan MJ; Anwyl R
beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
00
230363222 2004 JOURNAL OF NEUROSCIENCE 24(30):6799-6809
Tong LQ; Balazs R; Thornton PL; Cotman CW
beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
231415223 2004 JOURNAL OF PEPTIDE RESEARCH 63(3):324-328
Cruz M; Tusell JM; Grillo-Bosch D; Albericio F; Serratosa J; Rabanal F; Giralt E
Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids
00
2325145224 2004 JOURNAL OF PEPTIDE SCIENCE 10(5):229-248
Verdier Y; Zarandi M; Penke B
Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: Binding sites and implications for Alzheimer's disease
00
233321225 2004 JOURNAL OF PHYSICAL CHEMISTRY A 108(29):6239-6247
Almeida DRP; Gasparro DM; Fulop F; Csizmadia IG
Pharmacophore fragment-based prediction and gas-phase ab initio optimization of carvedilol conformations
00
234141226 2004 JOURNAL OF PINEAL RESEARCH 36(4):224-231
Lahiri DK; Chen D; Ge YW; Bondy SC; Sharman EH
Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex
00
2351049233 2004 NEUROBIOLOGY OF AGING 25(5):581-587
Lahiri DK; Greig NH
Lethal weapon: amyloid beta-peptide, role in the oxidative stress and neurodegeneration of Alzheimer's disease
00
236236234 2004 NEUROBIOLOGY OF DISEASE 15(2):188-195
Gureviciene I; Ikonen S; Gureviclus K; Sarkaki A; van Groen T; Pussinen R; Ylinen A; Tanila H
Normal induction but accelerated decay of LTP in APP+PS1 transgenic mice
00
237272235 2004 NEUROBIOLOGY OF DISEASE 16(3):617-629
Heredia L; Lin R; Vigo FS; Kedikian G; Busciglio J; Lorenzo A
Deposition of amyloid fibrils promotes cell-surface accumulation of amyloid beta precursor protein
00
238880236 2004 NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 30(3):215-224
Agorogiannis EI; Agorogiannis GI; Papadimitriou A; Hadjigeorgiou GM
Protein misfolding in neurodegenerative diseases
00
239334237 2004 NEUROPSYCHOPHARMACOLOGY 29(5):860-868
Tohda C; Matsumoto N; Zou K; Meselhy MR; Komatsu K
A beta(25-35)-induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins
00
240252238 2004 NEUROSCIENCE 126(2):297-303
Misiti F; Martorana GE; Nocca G; Di Stasio E; Giardina B; Clementi ME
Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta-protein fragment (31-35) on isolated brain mitochondria
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
241453241 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(17):6623-6628
Iijima K; Liu HP; Chiang AS; Hearn SA; Konsolaki M; Zhong Y
Dissecting the pathological effects of human A beta 40 and A beta 42 in Drosophila: A potential model for Alzheimer's disease
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24213139242 2004 PROTEIN AND PEPTIDE LETTERS 11(3):213-228
Walsh DM; Selkoe DJ
Oligomers in the brain: The emerging role of soluble protein aggregates in neurodegeneration
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243354243 2004 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 55(4):1053-1062
Vaiana SM; Emanuele A; Palma-Vittorelli MB; Palma MU
Irreversible formation of intermediate BSA oligomers requires and induces conformational changes
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244195244 2004 REDOX-ACTIVE METALS IN NEUROLOGICAL DISORDERS 1012:153-163
Huang XD; Moir RD; Tanzi RE; Bush AI; Rogers JT
Redox-active metals, oxidative stress, and Alzheimer's disease pathology
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2459103245 2004 SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 15(1):3-16
Dobson CM
Principles of protein folding, misfolding and aggregation
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2466127246 2004 SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 15(1):17-29
Barral JM; Broadley SA; Schaffar G; Hartl FU
Roles of molecular chaperones in protein misfolding diseases
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