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Nodes: 246
Authors: 958,
Journals: 112,
Outer References: 9412
Collection span: 2002 - 2004
View: Overview. Sorted by journal name.
Page 1: 1 (ACTA NEUROBIOLOGIAE EXPERIMENTALIS) 2 (JOURNAL OF MEDICINAL CHEMISTRY) 3 (NEUROSCIENCE)
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 4 | 97 | 176 2004 ACTA NEUROBIOLOGIAE EXPERIMENTALIS 64(1):19-31 Zekanowski C; Religa D; Graff C; Filipek S; Kuznicki J Genetic aspects of Alzheimer's disease | 0 | 2 |
| 2 | 9 | 93 | 177 2004 ACTA NEUROBIOLOGIAE EXPERIMENTALIS 64(1):71-79 Koudinov AR; Berezov TT Alzheimer's amyloid-beta (A beta) is an essential synaptic protein, not neurotoxic junk | 0 | 0 |
| 3 | 1 | 40 | 178 2004 ACTA NEUROBIOLOGIAE EXPERIMENTALIS 64(1):99-105 Kihara T; Shimohama S Alzheimer's disease and acetylcholine receptors | 0 | 0 |
| 4 | 2 | 57 | 179 2004 ACTA NEUROPATHOLOGICA 107(5):389-398 Maat-Schieman MLC; Yamaguchi H; Hegeman-Kleinn IM; Welling-Graafland C; Natte R; Roos RAC; van Duinen SG Glial reactions and the clearance of amyloid beta protein in the brains of patients with hereditary cerebral hemorrhage with amyloidosis-Dutch type | 0 | 0 |
| 5 | 1 | 49 | 1 2002 AMERICAN JOURNAL OF PATHOLOGY 161(5):1935-1948 Sousa MM; Fernandes R; Palha JA; Taboada A; Vieira P; Saraiva MJ Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro | 2 | 7 |
| 6 | 2 | 49 | 57 2003 AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS 10(2):80-85 Robakis NK An Alzheimer's disease hypothesis based on transcriptional dysregulation | 0 | 1 |
| 7 | 2 | 92 | 180 2004 ANNALS OF INTERNAL MEDICINE 140(8):627-638 Selkoe DJ Alzheimer disease: Mechanistic understanding predicts novel therapies | 0 | 0 |
| 8 | 2 | 35 | 58 2003 ANNALS OF NEUROLOGY 54(6):781-789 Lu DC; Shaked GM; Masliah E; Bredesen DE; Koo EH Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes | 1 | 1 |
| 9 | 1 | 14 | 181 2004 ANNALS OF NEUROLOGY 55(3):303-305 Jagust W The proteomics of positron emission tomography | 0 | 0 |
| 10 | 3 | 69 | 182 2004 ANNALS OF NEUROLOGY 55(6):801-814 Trinchese F; Liu SM; Battaglia F; Walter S; Mathews PM; Arancio O Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 1 | 100 | 2 2002 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 37 37:31-40 Morgan TE; Krafft GA Emerging themes in Alzheimer's disease research: Paradigm shift in drug discovery | 0 | 0 |
| 12 | 1 | 155 | 3 2002 ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS 3:67-99 Selkoe DJ; Podlisny MB Deciphering the genetic basis of Alzheimer's disease | 2 | 22 |
| 13 | 6 | 199 | 59 2003 ANNUAL REVIEW OF NEUROSCIENCE 26:267-298 Caughey B; Lansbury PT Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders | 7 | 31 |
| 14 | 7 | 178 | 60 2003 ANNUAL REVIEW OF NEUROSCIENCE 26:627-656 Bonini NM; Fortini ME Human neurodegenerative disease modeling using Drosophila | 0 | 3 |
| 15 | 1 | 150 | 61 2003 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 43:545-584 Selkoe DJ; Schenk D Alzheimer's disease: Molecular understanding predicts amyloid-based therapeutics | 7 | 29 |
| 16 | 1 | 47 | 62 2003 BEHAVIOURAL BRAIN RESEARCH 147(1-2):73-82 Romano A; Serafino A; Krasnowska E; Ciotti MT; Calissano P; Ruberti F; Galli C Neuronal fibrillogenesis: amyloid fibrils from primary neuronal cultures impair long-term memory in the crab Chasmagnathus | 0 | 0 |
| 17 | 5 | 182 | 63 2003 BEHAVIOURAL PHARMACOLOGY 14(5-6):419-438 Higgins GA; Jacobsen H Transgenic mouse models of Alzheimer's disease: phenotype and application | 0 | 2 |
| 18 | 1 | 34 | 4 2002 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 296(5):1317-1321 Rovira C; Arbez N; Mariani J A beta(25-35) and A beta(1-40) act on different calcium channels in CA1 hippocampal neurons | 0 | 4 |
| 19 | 1 | 20 | 64 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 301(3):699-703 Takata K; Kitamura Y; Kakimura J; Shibagaki K; Tsuchiya D; Taniguchi T; Smith MA; Perry G; Shimohama S Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis | 0 | 2 |
| 20 | 2 | 37 | 65 2003 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 303(2):496-503 Tobisawa S; Hozumi Y; Arawaka S; Koyama S; Wada M; Nagai M; Aoki M; Itoyama Y; Goto K; Kato T Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice | 0 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 2 | 53 | 5 2002 BIOCHEMICAL SOCIETY TRANSACTIONS 30:574-578 Wisniewski T; Brown DR; Sigurdsson EM Therapeutics in Alzheimer's and prion diseases | 0 | 1 |
| 22 | 2 | 58 | 66 2003 BIOCHEMISTRY 42(15):4492-4498 Kumita JR; Weston CJ; Choo-Smith LP; Woolley GA; Smart OS Prevention of peptide fibril formation in an aqueous environment by mutation of a single residue to Aib | 0 | 1 |
| 23 | 1 | 48 | 67 2003 BIOCHEMISTRY 42(31):9507-9514 Wang SSS; Tobler SA; Good TA; Fernandez EJ Hydrogen exchange-mass spectrometry analysis of beta-Amyloid peptide structure | 1 | 2 |
| 24 | 3 | 79 | 68 2003 BIOCHEMISTRY 42(36):10863-10873 Cottingham MG; Voskuil JLA; Vaux DJT The intact human acetylcholinesterase C-terminal oligomerization domain is alpha-helical in situ and in isolation, but a shorter fragment forms beta-sheet-rich amyloid fibrils and protofibrillar oligomers | 0 | 4 |
| 25 | 3 | 44 | 69 2003 BIOCHEMISTRY 42(40):11682-11692 Miller DL; Currie JR; Mehta PD; Potempska A; Hwang YW; Wegiel J Humoral immune response to fibrillar beta-amyloid peptide | 0 | 1 |
| 26 | 9 | 76 | 70 2003 BIOCHEMISTRY 42(44):12749-12760 Chromy BA; Nowak RJ; Lambert MP; Viola KL; Chang L; Velasco PT; Jones BW; Fernandez SJ; Lacor PN; Horowitz P; Finch CE; Krafft GA; Klein WL Self-assembly of A beta(1-42) into globular neurotoxins | 1 | 4 |
| 27 | 4 | 27 | 71 2003 BIOCHEMISTRY 42(48):14092-14098 Kheterpal I; Lashuel HA; Hartley DM; Wlaz T; Lansbury PT; Wetzel R A beta protofibrils possess a stable core structure resistant to hydrogen exchange | 1 | 3 |
| 28 | 9 | 88 | 183 2004 BIOCHEMISTRY 43(23):7365-7381 Hurshman AR; White JT; Powers ET; Kelly JW Transthyretin aggregation under partially denaturing conditions is a downhill polymerization | 0 | 0 |
| 29 | 2 | 60 | 72 2003 BIOESSAYS 25(3):283-288 Robinson SR; Bishop GM; Munch G Alzheimer vaccine: amyloid-beta on trial | 2 | 5 |
| 30 | 3 | 12 | 73 2003 BIOESSAYS 25(10):1024-1024 Koudinova NV Alzheimer's amyloid beta oligomers and lipoprotein apoA beta: mistaken identity is possible | 1 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 3 | 30 | 184 2004 BIOPHYSICAL JOURNAL 86(6):3585-3597 Mobley DL; Cox DL; Singh RRP; Maddox MW; Longo ML Modeling amyloid beta-peptide insertion into lipid bilayers | 0 | 0 |
| 32 | 5 | 86 | 185 2004 BIOPOLYMERS 76(1):4-14 Bateman DA; Chakrabartty A Interactions of Alzheimer amyloid peptides with cultured cells and brain tissue, and their biological consequences | 0 | 0 |
| 33 | 1 | 50 | 186 2004 BRAIN 127:73-88 Jonsson PA; Ernhill K; Andersen PM; Bergemalm D; Brannstrom T; Gredal O; Nilsson P; Marklund SL Minute quantities of misfolded mutant superoxide dismutase-1 cause amyotrophic lateral sclerosis | 0 | 3 |
| 34 | 1 | 37 | 74 2003 BRAIN RESEARCH 968(2):263-272 Raymond CR; Ireland DR; Abraham WC NMDA receptor regulation by amyloid-beta does not account for its inhibition of LTP in rat hippocampus | 4 | 4 |
| 35 | 1 | 21 | 75 2003 BRAIN RESEARCH 990(1-2):141-147 Tohda C; Tamura T; Komatsu K Repair of amyloid beta(25-35)-induced memory impairment and synaptic loss by a Kampo formula, Zokumei-to | 1 | 1 |
| 36 | 1 | 53 | 187 2004 BRAIN RESEARCH 998(1):73-82 Kasa P; Papp H; Kasa P; Pakaski M; Balaspiri L Effects of amyloid-beta on cholinergic and acetylcholinesterase-positive cells in cultured basal forebrain neurons of embryonic rat brain | 0 | 0 |
| 37 | 2 | 58 | 188 2004 BRAIN RESEARCH 1000(1-2):1-7 Butterfield DA Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain | 0 | 2 |
| 38 | 3 | 103 | 189 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(3):326-335 Johansson J; Weaver TE; Tjernberg LO Proteolytic generation and aggregation of peptides from transmembrane regions: lung surfactant protein C and amyloid beta-peptide | 0 | 1 |
| 39 | 6 | 278 | 190 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(14):1729-1750 Bonifati V; Oostra BA; Heutink P Unraveling the pathogenesis of Parkinson's disease - the contribution of monogenic forms | 0 | 0 |
| 40 | 1 | 66 | 76 2003 CHEMISTRY & BIOLOGY 10(2):149-159 Kapurniotu A; Buck A; Weber M; Schmauder A; Hirsch T; Bernhagen J; Tatarek-Nossol M Conformational restriction via cyclization in beta-amyloid peptide A beta(1-28) leads to an inhibitor of A beta(1-28) amyloidogenesis and cytotoxicity | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 5 | 137 | 77 2003 CNS DRUGS 17(9):641-652 Butterfield DA; Pocernich CB The glutamatergic system and Alzheimer's disease - Therapeutic implications | 0 | 4 |
| 42 | 3 | 91 | 78 2003 CURRENT MEDICINAL CHEMISTRY 10(24):2651-2659 Butterfield DA Amyloid beta-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease grain: Mechanisms and consequences | 0 | 0 |
| 43 | 3 | 116 | 191 2004 CURRENT MEDICINAL CHEMISTRY 11(4):491-499 Chow MKM; Lomas DA; Bottomley SP Promiscuous beta-strand interactions and the conformational diseases | 0 | 2 |
| 44 | 5 | 81 | 79 2003 CURRENT OPINION IN GENETICS & DEVELOPMENT 13(3):253-261 Berke SJS; Paulson HL Protein aggregation and the ubiquitin proteasome pathway: gaining the UPPer hand on neurodegeneration | 3 | 18 |
| 45 | 5 | 71 | 80 2003 CURRENT OPINION IN RHEUMATOLOGY 15(6):737-744 Askanas V; Engel WK Proposed pathogenetic cascade of inclusion-body myositis: importance of amyloid-beta, misfolded proteins, predisposing genes, and aging | 0 | 2 |
| 46 | 4 | 87 | 81 2003 CURRENT OPINION IN STRUCTURAL BIOLOGY 13(2):146-159 Thirumalai D; Klimov DK; Dima RI Emerging ideas on the molecular basis of protein and peptide aggregation | 2 | 13 |
| 47 | 2 | 83 | 82 2003 CYTOGENETIC AND GENOME RESEARCH 100(1-4):261-275 Kobayashi T; Kakizuka A Molecular analyses of Machado-Joseph disease | 0 | 3 |
| 48 | 1 | 45 | 6 2002 EMBO JOURNAL 21(22):6005-6014 Sandilands A; Hutcheson AM; Long HA; Prescott AR; Vrensen G; Loster J; Klopp N; Lutz RB; Graw J; Masaki S; Dobson CM; MacPhee CE; Quinlan RA Altered aggregation properties of mutant gamma-crystallins cause inherited cataract | 3 | 13 |
| 49 | 3 | 64 | 83 2003 EMBO JOURNAL 22(3):355-361 Temussi PA; Masino L; Pastore A From Alzheimer to Huntington: why is a structural understanding so difficult? | 1 | 16 |
| 50 | 1 | 35 | 84 2003 EUROPEAN JOURNAL OF BIOCHEMISTRY 270(4):654-663 Frost D; Gorman PM; Yip CM; Chakrabartty A Co-incorporation of A beta 40 and A beta 42 to form mixed pre-fibrillar aggregates | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 11 | 58 | 192 2004 EUROPEAN JOURNAL OF NEUROSCIENCE 19(10):2839-2846 Klyubin I; Walsh DM; Cullen WK; Fadeeva JV; Anwyl R; Selkoe DJ; Rowan MJ Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo | 0 | 0 |
| 52 | 1 | 79 | 193 2004 EXPERIMENTAL NEUROLOGY 188(2):224-237 Wen PH; Hof PR; Chen XP; Gluck K; Austin G; Younkin SG; Younkin LH; DeGasperi R; Sosa MAG; Robakis NK; Haroutunian V; Elder GA The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice | 0 | 0 |
| 53 | 1 | 44 | 7 2002 FASEB JOURNAL 16(13) Kim HJ; Chae SC; Lee DK; Chromy B; Lee SC; Park YC; Klein WL; Krafft GA; Hong ST Selective neuronal degeneration induced by soluble oligomeric amyloid beta-protein | 0 | 0 |
| 54 | 5 | 42 | 194 2004 FASEB JOURNAL 18(10) Barnham KJ; Haeffner F; Ciccotosto GD; Curtain CC; Tew D; Mavros C; Beyreuther K; Carrington D; Masters CL; Cherny RA; Cappai R; Bush AI Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid | 0 | 0 |
| 55 | 1 | 57 | 8 2002 FREE RADICAL BIOLOGY AND MEDICINE 33(9):1194-1199 Smith MA; Casadesus G; Joseph JA; Perry G Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain | 0 | 9 |
| 56 | 1 | 64 | 9 2002 FREE RADICAL RESEARCH 36(12):1307-1313 Butterfield DA Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer's disease brain. A review | 2 | 32 |
| 57 | 2 | 21 | 195 2004 HISTOLOGY AND HISTOPATHOLOGY 19(3):845-852 Fukuchi K; Hart M; Yan Z; Hassell JR; Li L Transgenic mice overexpressing both amyloid B-protein and perlecan in pancreatic acinar cells | 0 | 0 |
| 58 | 2 | 68 | 10 2002 HUMAN MOLECULAR GENETICS 11(23):2895-2904 Chan HYE; Warrick JM; Andriola I; Merry D; Bonini NM Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila | 3 | 19 |
| 59 | 1 | 26 | 11 2002 HUMAN MOLECULAR GENETICS 11(25):3209-3219 Deery EC; Vithana EN; Newbold RJ; Gallon VA; Bhattacharya SS; Warren MJ; Hunt DM; Wilkie SE Disease mechanism for retinitis pigmentosa (RP11) caused by mutations in the splicing factor gene PRPF31 | 0 | 6 |
| 60 | 1 | 35 | 12 2002 INTERNATIONAL IMMUNOPHARMACOLOGY 2(13-14):1833-1840 Jong YJI; Dalemar LR; Seehra K; Baenziger NL Bradykinin receptor modulation in cellular models of aging and Alzheimer's disease | 0 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 5 | 308 | 85 2003 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 35(11):1505-1535 Ling Y; Morgan K; Kalsheker N Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease | 3 | 5 |
| 62 | 1 | 61 | 196 2004 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36(10):2066-2076 Clementi ME; Martorana GE; Pezzotti M; Giardina B; Misiti F Methionine 35 oxidation reduces toxic effects of the amyloid beta-protein fragment (31-35) on human red blood cell | 0 | 0 |
| 63 | 1 | 69 | 13 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(35):32046-32053 Dahlgren KN; Manelli AM; Stine WB; Baker LK; Krafft GA; LaDu MJ Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability | 24 | 37 |
| 64 | 1 | 55 | 14 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(36):33012-33017 Mohajeri MH; Saini K; Schultz JG; Wollmer MA; Hock C; Nitsch RM Passive immunization against beta-amyloid peptide protects central nervous system (CNS) neurons from increased vulnerability associated with an Alzheimer's disease-causing mutation | 1 | 8 |
| 65 | 1 | 48 | 15 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(43):40173-40176 Hou LM; Kang I; Marchant RE; Zagorski MG Methionine 35 oxidation reduces fibril assembly of the amyloid A beta-(1-42) peptide of Alzheimer's disease | 7 | 12 |
| 66 | 1 | 35 | 16 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(43):41032-41037 Poirier MA; Li HL; Macosko J; Cai SW; Amzel M; Ross CA Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization | 8 | 27 |
| 67 | 1 | 65 | 17 2002 JOURNAL OF BIOLOGICAL CHEMISTRY 277(45):42881-42890 Lashuel HA; Hartley DM; Balakhaneh D; Aggarwal A; Teichberg S; Callaway DJE New class of inhibitors of amyloid-beta fibril formation - Implications for the mechanism of pathogenesis in Alzheimer's disease | 1 | 6 |
| 68 | 5 | 74 | 86 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(13):11612-11622 Stine WB; Dahlgren KN; Krafft GA; LaDu MJ In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis | 7 | 16 |
| 69 | 2 | 70 | 87 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(15):13047-13055 Nucifora FC; Ellerby LM; Wellington CL; Wood JD; Herring WJ; Sawa A; Hayden MR; Dawson VL; Dawson TM; Ross CA Nuclear localization of a non-caspase truncation product of atrophin-1, with an expanded polyglutamine repeat, increases cellular toxicity | 0 | 5 |
| 70 | 5 | 65 | 88 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(25):23187-23195 Qahwash I; Weiland KL; Lu YF; Sarver RW; Kletzien RF; Yan RQ Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates | 1 | 1 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 1 | 53 | 89 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(26):23221-23226 Morelli L; Llovera R; Gonzalez SA; Affranchino JL; Prelli F; Frangione B; Ghiso J; Castano EM Differential degradation of amyloid beta genetic variants associated with hereditary dementia or stroke by insulin-degrading enzyme | 3 | 4 |
| 72 | 4 | 28 | 90 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(26):23648-23655 Yoshiike Y; Chui DH; Akagi T; Tanaka N; Takashima A Specific compositions of amyloid-beta peptides as the determinant of toxic beta-aggregation | 0 | 0 |
| 73 | 2 | 58 | 91 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(30):27971-27980 Minogue AM; Schmid AW; Fogarty MP; Moore AC; Campbell VA; Herron CE; Lynch MA Activation of the c-Jun N-terminal kinase signaling cascade mediates the effect of amyloid-beta on long term potentiation and cell death in hippocampus - A role for interleukin-1 beta? | 0 | 4 |
| 74 | 2 | 34 | 92 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(36):34717-34724 Tanaka M; Machida Y; Nishikawa Y; Akagi T; Hashikawa T; Fujisawa T; Nukina N Expansion of polyglutamine induces the formation of quasi-aggregate in the early stage of protein fibrillization | 0 | 1 |
| 75 | 1 | 38 | 93 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):34874-34881 Chalifour RJ; McLaughlin RW; Lavoie L; Morissette C; Tremblay N; Boule M; Sarazin P; Stea D; Lacombe D; Tremblay P; Gervais F Stereoselective interactions of peptide inhibitors with the beta-amyloid peptide | 0 | 2 |
| 76 | 5 | 67 | 94 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):34882-34889 Bitan G; Vollers SS; Teplow DB Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization | 2 | 5 |
| 77 | 1 | 44 | 95 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(37):35317-35324 Schmechel A; Zentgraf H; Scheuermann S; Fritz G; Pipkorn RD; Reed J; Beyreuther K; Bayer TA; Multhaup G Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies | 0 | 0 |
| 78 | 2 | 24 | 96 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(39):37314-37320 Leissring MA; Lu A; Condron MM; Teplow DB; Stein RL; Farris W; Selkoe DJ Kinetics of amyloid beta-protein degradation determined by novel fluorescence-and fluorescence polarization-based assays | 1 | 1 |
| 79 | 2 | 47 | 97 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(42):41452-41461 Busch A; Engemann S; Lurz R; Okazawa H; Lehrach H; Wanker EE Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin - A potential mechanism for loss of huntingtin function in Huntington's disease | 0 | 4 |
| 80 | 1 | 48 | 98 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(43):41890-41899 Kim SJ; Sung JY; Um JW; Hattori N; Mizuno Y; Tanaka K; Paik SR; Kim J; Chung KC Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain | 1 | 2 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 2 | 60 | 99 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(44):42959-42965 Barnham KJ; Ciccotosto GD; Tickler AK; Ali FE; Smith DG; Williamson NA; Lam YH; Carrington D; Tew D; Kocak G; Volitakis I; Separovic F; Barrow CJ; Wade JD; Masters CL; Cherny RA; Curtain CC; Bush AI; Cappai R Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation | 4 | 10 |
| 82 | 1 | 39 | 100 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(46):46179-46187 Murakami K; Irie K; Morimoto A; Ohigashi H; Shindo M; Nagao M; Shimizu T; Shirasawa T Neurotoxicity and physicochemical properties of A beta mutant peptides from cerebral amyloid angiopathy - Implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease | 1 | 1 |
| 83 | 1 | 56 | 101 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(49):48644-48650 Devlin GL; Carver JA; Bottomley SP The selective inhibition of serpin aggregation by the molecular chaperone, alpha-crystallin, indicates a nucleation-dependent specificity | 0 | 1 |
| 84 | 1 | 42 | 102 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(51):51035-51043 Chyung JH; Selkoe DJ Inhibition of receptor-mediated endocytosis demonstrates generation of amyloid beta-protein at the cell surface | 0 | 1 |
| 85 | 2 | 47 | 103 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(51):51770-51778 Laurine E; Gregoire C; Fandrich M; Engemann S; Marchal S; Thion L; Mohr M; Monsarrat B; Michel B; Dobson CM; Wanker E; Erard M; Verdier JM Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease | 1 | 1 |
| 86 | 3 | 34 | 104 2003 JOURNAL OF BIOLOGICAL CHEMISTRY 278(52):52519-52523 Capell A; Kaether C; Edbauer D; Shirotani K; Merkl S; Steiner H; Haass C Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domain | 0 | 2 |
| 87 | 1 | 40 | 197 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(13):12206-12212 Green JD; Goldsbury C; Kistler J; Cooper GJS; Aebi U Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation | 0 | 0 |
| 88 | 3 | 73 | 198 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(13):13183-13189 Sirangelo I; Malmo C; Iannuzzi C; Mezzogiorno A; Bianco MR; Papa M; Irace G Fibrillogenesis and cytotoxic activity of the amyloid-forming apomyoglobin mutant W7FW14F | 0 | 0 |
| 89 | 3 | 56 | 199 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(14):14111-14119 Plakoutsi G; Taddei N; Stefani M; Chiti F Aggregation of the acylphosphatase from Sulfolobus solfataricus - The folded and partially unfolded states can both be precursors for amyloid formation | 0 | 0 |
| 90 | 1 | 53 | 200 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(15):14673-14678 Nagano S; Huang XD; Moir RD; Payton SM; Tanzi RE; Bush AI Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links beta-amyloid (A beta) and generates A beta-COX-2 hetero-oligomers that are increased in Alzheimer's disease | 0 | 0 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 5 | 56 | 201 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(23):24236-24245 Nilsson M; Wang X; Rodziewicz-Motowidlo S; Janowski R; Lindstrom V; Onnerfjord P; Westermark G; Grzonka Z; Jaskolski M; Grubb A Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C - Use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C | 0 | 1 |
| 92 | 3 | 58 | 202 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(30):31374-31382 Bucciantini M; Calloni G; Chiti F; Formigli L; Nosi D; Dobson CM; Stefani M Prefibrillar amyloid protein aggregates share common features of cytotoxicity | 0 | 0 |
| 93 | 6 | 65 | 203 2004 JOURNAL OF CHEMICAL PHYSICS 120(12):5809-5823 Friedel M; Shea JE Self-assembly of peptides into a beta-barrel motif | 0 | 0 |
| 94 | 2 | 28 | 204 2004 JOURNAL OF CHEMICAL PHYSICS 120(17):8307-8317 Tiana G; Simona F; Brogliaa RA; Colombo G Thermodynamics of beta-amyloid fibril formation | 0 | 0 |
| 95 | 2 | 15 | 18 2002 JOURNAL OF CLINICAL INVESTIGATION 110(9):1219-1220 Perlmutter DH The cellular response to aggregated proteins associated with human disease | 0 | 2 |
| 96 | 1 | 80 | 19 2002 JOURNAL OF CLINICAL INVESTIGATION 110(9):1221-1232 Horwich A Protein aggregation in disease: a role for folding intermediates forming specific multimeric interactions | 3 | 19 |
| 97 | 1 | 65 | 20 2002 JOURNAL OF CLINICAL INVESTIGATION 110(10):1375-1381 Selkoe DJ Deciphering the genesis and fate of amyloid beta-protein yields novel therapies for Alzheimer disease | 2 | 22 |
| 98 | 2 | 54 | 205 2004 JOURNAL OF CLINICAL INVESTIGATION 113(10):1456-1464 Postina R; Schroeder A; Dewachter I; Bohl J; Schmitt U; Kojro E; Prinzen C; Endres K; Hiemke C; Blessing M; Flamez P; Dequenne A; Godaux E; van Leuven F; Fahrenholz F A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model | 0 | 1 |
| 99 | 1 | 61 | 105 2003 JOURNAL OF COMPARATIVE NEUROLOGY 462(4):371-381 German DC; Yazdani U; Speciale SG; Pasbakish P; Games D; Liang CL Cholinergic neuropathology in a mouse model of Alzheimer's disease | 0 | 4 |
| 100 | 2 | 74 | 106 2003 JOURNAL OF LIPID RESEARCH 44(8):1423-1430 Raffai RL; Weisgraber KH Cholesterol: from heart attacks to Alzheimer's disease | 0 | 4 |
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