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Tue Aug 31 16:33:17 2004
Naturally secreted oligomers of amyloid beta protein potently
inhibit hippocampal long-term potentiation in vivo

Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R,
Wolfe MS, Rowan MJ, Selkoe DJ
NATURE 416 (6880): 535-539 APR 4 2002
and the citing papers

Nodes: 246
Authors: 958, Journals: 112, Outer References: 9412
Collection span: 2002 - 2004
View: Overview. Sorted by year, source, volume, issue, page.
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#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
201556201 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(23):24236-24245
Nilsson M; Wang X; Rodziewicz-Motowidlo S; Janowski R; Lindstrom V; Onnerfjord P; Westermark G; Grzonka Z; Jaskolski M; Grubb A
Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C - Use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C
01
202358202 2004 JOURNAL OF BIOLOGICAL CHEMISTRY 279(30):31374-31382
Bucciantini M; Calloni G; Chiti F; Formigli L; Nosi D; Dobson CM; Stefani M
Prefibrillar amyloid protein aggregates share common features of cytotoxicity
00
203665203 2004 JOURNAL OF CHEMICAL PHYSICS 120(12):5809-5823
Friedel M; Shea JE
Self-assembly of peptides into a beta-barrel motif
00
204228204 2004 JOURNAL OF CHEMICAL PHYSICS 120(17):8307-8317
Tiana G; Simona F; Brogliaa RA; Colombo G
Thermodynamics of beta-amyloid fibril formation
00
205254205 2004 JOURNAL OF CLINICAL INVESTIGATION 113(10):1456-1464
Postina R; Schroeder A; Dewachter I; Bohl J; Schmitt U; Kojro E; Prinzen C; Endres K; Hiemke C; Blessing M; Flamez P; Dequenne A; Godaux E; van Leuven F; Fahrenholz F
A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model
01
206527206 2004 JOURNAL OF MEDICINAL CHEMISTRY 47(13):3329-3333
Wang ZQ; Chang L; Klein WL; Thatcher GRJ; Venton DL
Per-6-substituted-per-6-deoxy beta-cyclodextrins inhibit the formation of beta-amyloid peptide derived soluble oligomers
00
207142207 2004 JOURNAL OF MOLECULAR BIOLOGY 336(3):775-786
Hall D; Edskes H
Silent prions lying in wait: A two-hit model of prion/amyloid formation and infection
00
208459208 2004 JOURNAL OF MOLECULAR BIOLOGY 338(5):943-957
Gliozzi A; Rosano C; Canale C; Bolognesi M; Plakoutsi G; Bucciantini M; Chiti F; Stefani M
Monitoring the process of HypF fibrillization and liposome permeabilization by protofibrils
00
2093112209 2004 JOURNAL OF MOLECULAR MEDICINE-JMM 82(3):163-174
Bonifati V; Oostra BA; Heutink P
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease
13
210481210 2004 JOURNAL OF MOLECULAR NEUROSCIENCE 23(3):235-246
Manelli AM; Stine WB; Van Eldik LJ; Ladu MJ
ApoE and A beta 1-42 interactions
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
211123211 2004 JOURNAL OF NEUROCHEMISTRY 88(2):281-290
Gibson G; Gunasekera N; Lee M; Lelyveld V; El-Agnaf OMA; Wright A; Austen B
Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia
00
212332212 2004 JOURNAL OF NEUROCHEMISTRY 89(4):807-811
Zlokovic BV
Clearing amyloid through the blood-brain barrier
00
213127213 2004 JOURNAL OF NEUROCHEMISTRY 89(6):1409-1416
Chang WP; Koelsch G; Wong S; Downs D; Da HN; Weerasena V; Gordon B; Devasamudram T; Bilcer G; Ghosh AK; Tang J
In vivo inhibition of A beta production by memapsin 2 (beta-secretase) inhibitors
00
214263214 2004 JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 63(3):255-261
Takuma H; Tomiyama T; Kuida K; Mori H
Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo
00
215353215 2004 JOURNAL OF NEUROSCIENCE 24(1):269-281
Qin ZH; Wang YM; Sapp E; Cuiffo B; Wanker E; Hayden MR; Kegel KB; Aronin N; DiFiglia M
Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction
02
216786216 2004 JOURNAL OF NEUROSCIENCE 24(11):2716-2726
Lin H; Zhai JB; Canete-Soler R; Schlaepfer WW
3 ' untranslated region in a light neurofilament (NF-L) mRNA triggers aggregation of NF-L and mutant superoxide dismutase 1 proteins in neuronal cells
00
217468217 2004 JOURNAL OF NEUROSCIENCE 24(13):3370-3378
Wang QW; Walsh DM; Rowan MJ; Selkoe DJ; Anwyl R
Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
22
218252218 2004 JOURNAL OF NEUROSCIENCE 24(13):3444-3452
Suo ZM; Wu M; Citron BA; Wong GT; Festoff BW
Abnormality of G-protein-coupled receptor kinases at prodromal and early stages of Alzheimer's disease: An association with early beta-amyloid accumulation
00
219340219 2004 JOURNAL OF NEUROSCIENCE 24(16):3899-3906
Greeve I; Kretzschmar D; Tschape JA; Beyn A; Brellinger C; Schweizer M; Nitsch RM; Reifegerste R
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila
00
220448220 2004 JOURNAL OF NEUROSCIENCE 24(19):4535-4540
Stern EA; Bacskai BJ; Hickey GA; Attenello FJ; Lombardo JA; Hyman BT
Cortical synaptic integration in vivo is disrupted by amyloid-beta plaques
00
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
221554221 2004 JOURNAL OF NEUROSCIENCE 24(27):6049-6056
Wang QW; Rowan MJ; Anwyl R
beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
00
222363222 2004 JOURNAL OF NEUROSCIENCE 24(30):6799-6809
Tong LQ; Balazs R; Thornton PL; Cotman CW
beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
00
223415223 2004 JOURNAL OF PEPTIDE RESEARCH 63(3):324-328
Cruz M; Tusell JM; Grillo-Bosch D; Albericio F; Serratosa J; Rabanal F; Giralt E
Inhibition of beta-amyloid toxicity by short peptides containing N-methyl amino acids
00
2245145224 2004 JOURNAL OF PEPTIDE SCIENCE 10(5):229-248
Verdier Y; Zarandi M; Penke B
Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: Binding sites and implications for Alzheimer's disease
00
225321225 2004 JOURNAL OF PHYSICAL CHEMISTRY A 108(29):6239-6247
Almeida DRP; Gasparro DM; Fulop F; Csizmadia IG
Pharmacophore fragment-based prediction and gas-phase ab initio optimization of carvedilol conformations
00
226141226 2004 JOURNAL OF PINEAL RESEARCH 36(4):224-231
Lahiri DK; Chen D; Ge YW; Bondy SC; Sharman EH
Dietary supplementation with melatonin reduces levels of amyloid beta-peptides in the murine cerebral cortex
00
227580227 2004 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 126(7):1992-2005
Hou LM; Shao HY; Zhang YB; Li H; Menon NK; Neuhaus EB; Brewer JM; Byeon IJL; Ray DG; Vitek MP; Iwashita T; Makula RA; Przybyla AB; Zagorski MG
Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the met35 oxidation state affects the mechanism of amyloid formation
01
2281128228 2004 LANCET 363(9402):51-61
Collins SJ; Lawson VA; Masters CL
Transmissible spongiform encephalopathies
01
229318229 2004 NANO LETTERS 4(6):1029-1034
Haes AJ; Hall WP; Chang L; Klein WL; Van Duyne RP
A localized surface plasmon resonance biosensor: First steps toward an assay for Alzheimer's disease
01
2303183230 2004 NATURE REVIEWS NEUROSCIENCE 5(5):347-360
Iadecola C
Neurovascular regulation in the normal brain and in Alzheimer's disease
01
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
231850231 2004 NEUROBIOLOGY OF AGING 25(5):563-568
Butterfield DA; Bush AI
Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide
11
2321378232 2004 NEUROBIOLOGY OF AGING 25(5):569-580
Klein WL; Stine WB; Teplow DB
Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease
11
2331049233 2004 NEUROBIOLOGY OF AGING 25(5):581-587
Lahiri DK; Greig NH
Lethal weapon: amyloid beta-peptide, role in the oxidative stress and neurodegeneration of Alzheimer's disease
00
234236234 2004 NEUROBIOLOGY OF DISEASE 15(2):188-195
Gureviciene I; Ikonen S; Gureviclus K; Sarkaki A; van Groen T; Pussinen R; Ylinen A; Tanila H
Normal induction but accelerated decay of LTP in APP+PS1 transgenic mice
00
235272235 2004 NEUROBIOLOGY OF DISEASE 16(3):617-629
Heredia L; Lin R; Vigo FS; Kedikian G; Busciglio J; Lorenzo A
Deposition of amyloid fibrils promotes cell-surface accumulation of amyloid beta precursor protein
00
236880236 2004 NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 30(3):215-224
Agorogiannis EI; Agorogiannis GI; Papadimitriou A; Hadjigeorgiou GM
Protein misfolding in neurodegenerative diseases
00
237334237 2004 NEUROPSYCHOPHARMACOLOGY 29(5):860-868
Tohda C; Matsumoto N; Zou K; Meselhy MR; Komatsu K
A beta(25-35)-induced memory impairment, axonal atrophy, and synaptic loss are ameliorated by M1, a metabolite of protopanaxadiol-type saponins
00
238252238 2004 NEUROSCIENCE 126(2):297-303
Misiti F; Martorana GE; Nocca G; Di Stasio E; Giardina B; Clementi ME
Methionine 35 oxidation reduces toxic and pro-apoptotic effects of the amyloid beta-protein fragment (31-35) on isolated brain mitochondria
00
239543239 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(4):1075-1080
Zerbinatti CV; Wozniak DF; Cirrito J; Cam JA; Osaka H; Bales KR; Zhuo M; Paul SM; Holtzman DM; Bu GJ
Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein
12
240646240 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(14):4752-4757
Zhang QH; Powers ET; Nieva J; Huff ME; Dendle MA; Bieschke J; Glabe CG; Eschenmoser A; Wentworth P; Lerner RA; Kelly JW
Metabolite-initiated protein misfolding may trigger Alzheimer's disease
02
#LCRNCRNodes / Date / Journal / AuthorsLCSGCS
241453241 2004 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101(17):6623-6628
Iijima K; Liu HP; Chiang AS; Hearn SA; Konsolaki M; Zhong Y
Dissecting the pathological effects of human A beta 40 and A beta 42 in Drosophila: A potential model for Alzheimer's disease
00
24213139242 2004 PROTEIN AND PEPTIDE LETTERS 11(3):213-228
Walsh DM; Selkoe DJ
Oligomers in the brain: The emerging role of soluble protein aggregates in neurodegeneration
00
243354243 2004 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS 55(4):1053-1062
Vaiana SM; Emanuele A; Palma-Vittorelli MB; Palma MU
Irreversible formation of intermediate BSA oligomers requires and induces conformational changes
00
244195244 2004 REDOX-ACTIVE METALS IN NEUROLOGICAL DISORDERS 1012:153-163
Huang XD; Moir RD; Tanzi RE; Bush AI; Rogers JT
Redox-active metals, oxidative stress, and Alzheimer's disease pathology
00
2459103245 2004 SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 15(1):3-16
Dobson CM
Principles of protein folding, misfolding and aggregation
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2466127246 2004 SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 15(1):17-29
Barral JM; Broadley SA; Schaffar G; Hartl FU
Roles of molecular chaperones in protein misfolding diseases
00

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