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Nodes: 9502,
Authors: 17414,
Journals: 1567,
Outer References: 209860,
Words: 11576
Collection span: 1953 - 2005
View: Overview. Sorted by LCS.
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 3 | 62 | 21 1961 EXPERIMENTAL CELL RESEARCH 25(3):585-& HAYFLICK L; MOORHEAD PS SERIAL CULTIVATION OF HUMAN DIPLOID CELL STRAINS | 3044 | 3039 |
| 2 | 11 | 44 | 344 1965 EXPERIMENTAL CELL RESEARCH 37(3):614-& HAYFLICK L LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS | 2561 | 2560 |
| 3 | 23 | 68 | 448 1965 TEXAS REPORTS ON BIOLOGY AND MEDICINE 23:285-& HAYFLICK L TISSUE CULTURES AND MYCOPLASMAS | 925 | 923 |
| 4 | 0 | 19 | 68 1962 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 48(1):41-& CHANOCK RM; HAYFLICK L; BARILE MF GROWTH ON ARTIFICIAL MEDIUM OF AN AGENT ASSOCIATED WITH ATYPICAL PNEUMONIA AND ITS IDENTIFICATION AS A PPLO | 832 | 831 |
| 5 | 11 | 40 | 1458 1970 LABORATORY INVESTIGATION 23(1):86-& MARTIN GM; SPRAGUE CA; EPSTEIN CJ REPLICATIVE LIFE-SPAN OF CULTIVATED HUMAN CELLS - EFFECTS OF DONORS AGE, TISSUE, AND GENOTYPE | 632 | 891 |
| 6 | 5 | 33 | 6498 1990 NATURE 345(6274):458-460 HARLEY CB; FUTCHER AB; GREIDER CW TELOMERES SHORTEN DURING AGING OF HUMAN FIBROBLASTS | 493 | 1724 |
| 7 | 27 | 62 | 8058 1998 SCIENCE 279(5349):349-352 Bodnar AG; Ouellette M; Frolkis M; Holt SE; Chiu CP; et al. Extension of life-span by introduction of telomerase into normal human cells | 426 | 1466 |
| 8 | 13 | 31 | 7452 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(20):9363-9367 DIMRI GP; LEE XH; BASILE G; ACOSTA M; SCOTT C; et al. A BIOMARKER THAT IDENTIFIES SENESCENT HUMAN-CELLS IN CULTURE AND IN AGING SKIN IN-VIVO | 385 | 874 |
| 9 | 8 | 24 | 3147 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73(10):3584-3588 SCHNEIDER EL; MITSUI Y RELATIONSHIP BETWEEN INVITRO CELLULAR AGING AND INVIVO HUMAN AGE | 348 | 418 |
| 10 | 44 | 88 | 6518 1990 SCIENCE 249(4973):1129-1133 GOLDSTEIN S REPLICATIVE SENESCENCE - THE HUMAN FIBROBLAST COMES OF AGE | 322 | 491 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 4 | 22 | 246 1964 JOURNAL OF IMMUNOLOGY 92(6):958-& CLYDE WA MYCOPLASMA SPECIES IDENTIFICATION BASED UPON GROWTH INHIBITION BY SPECIFIC ANTISERA | 304 | 806 |
| 12 | 19 | 47 | 6885 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(21):10114-10118 ALLSOPP RC; VAZIRI H; PATTERSON C; GOLDSTEIN S; YOUNGLAI EV; et al. TELOMERE LENGTH PREDICTS REPLICATIVE CAPACITY OF HUMAN FIBROBLASTS | 303 | 950 |
| 13 | 1 | 31 | 130 1963 JOURNAL OF CELL BIOLOGY 17(2):299-& TODARO GJ; GREEN H QUANTITATIVE STUDIES OF GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES | 282 | 1724 |
| 14 | 16 | 57 | 6764 1992 EMBO JOURNAL 11(5):1921-1929 COUNTER CM; AVILION AA; LEFEUVRE CE; STEWART NG; GREIDER CW; et al. TELOMERE SHORTENING ASSOCIATED WITH CHROMOSOME INSTABILITY IS ARRESTED IN IMMORTAL CELLS WHICH EXPRESS TELOMERASE ACTIVITY | 280 | 1194 |
| 15 | 0 | 1 | 3302 1977 HDB BIOL AGING :159-186 Hayflick L The cellular basis for biological aging. In C.Finch and L.Hayflick (eds.). Handbook of the biology of aging | 247 | 247 |
| 16 | 11 | 27 | 7144 1994 EXPERIMENTAL CELL RESEARCH 211(1):90-98 NODA A; NING Y; VENABLE SF; PEREIRASMITH OM; SMITH JR CLONING OF SENESCENT CELL-DERIVED INHIBITORS OF DNA-SYNTHESIS USING AN EXPRESSION SCREEN | 227 | 1097 |
| 17 | 17 | 57 | 6512 1990 SCIENCE 247(4939):205-209 SESHADRI T; CAMPISI J REPRESSION OF C-FOS TRANSCRIPTION AND AN ALTERED GENETIC PROGRAM IN SENESCENT HUMAN-FIBROBLASTS | 217 | 379 |
| 18 | 10 | 18 | 2459 1974 JOURNAL OF CELL BIOLOGY 62(1):48-53 SMITH JR; HAYFLICK L VARIATION IN LIFE-SPAN OF CLONES DERIVED FROM HUMAN DIPLOID CELL STRAINS | 211 | 211 |
| 19 | 49 | 304 | 322 1965 BACTERIOLOGICAL REVIEWS 29(2):185-& HAYFLICK L; CHANOCK RM MYCOPLASMA SPECIES OF MAN | 203 | 203 |
| 20 | 18 | 73 | 7685 1997 CELL 88(5):593-602 Serrano M; Lin AW; McCurrach ME; Beach D; Lowe SW Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16(INK4a) | 202 | 1032 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 22 | 83 | 6671 1991 MUTATION RESEARCH 256(2-6):271-282 HARLEY CB TELOMERE LOSS - MITOTIC CLOCK OR GENETIC TIME BOMB | 200 | 675 |
| 22 | 6 | 28 | 1934 1972 NATURE 238(5358):26-& HOLLIDAY R; TARRANT GM ALTERED ENZYMES IN AGING HUMAN FIBROBLASTS | 199 | 367 |
| 23 | 16 | 34 | 6147 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(16):6042-6046 PEREIRASMITH OM; SMITH JR GENETIC-ANALYSIS OF INDEFINITE DIVISION IN HUMAN-CELLS - IDENTIFICATION OF 4 COMPLEMENTATION GROUPS | 199 | 340 |
| 24 | 17 | 38 | 4599 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78(8):5009-5013 ROHME D EVIDENCE FOR A RELATIONSHIP BETWEEN LONGEVITY OF MAMMALIAN-SPECIES AND LIFE SPANS OF NORMAL FIBROBLASTS INVITRO AND ERYTHROCYTES INVIVO | 176 | 222 |
| 25 | 17 | 51 | 6315 1989 MOLECULAR AND CELLULAR BIOLOGY 9(7):3088-3092 WRIGHT WE; PEREIRASMITH OM; SHAY JW REVERSIBLE CELLULAR SENESCENCE - IMPLICATIONS FOR IMMORTALIZATION OF NORMAL HUMAN-DIPLOID FIBROBLASTS | 171 | 326 |
| 26 | 9 | 38 | 6517 1990 SCIENCE 249(4969):666-669 STEIN GH; BEESON M; GORDON L FAILURE TO PHOSPHORYLATE THE RETINOBLASTOMA GENE-PRODUCT IN SENESCENT HUMAN FIBROBLASTS | 170 | 315 |
| 27 | 6 | 11 | 3135 1976 NEW ENGLAND JOURNAL OF MEDICINE 295(23):1302-1308 HAYFLICK L CELL BIOLOGY OF HUMAN AGING | 164 | 164 |
| 28 | 6 | 30 | 8028 1998 NATURE 396(6706):84-88 Kiyono T; Foster SA; Koop JI; McDougall JK; Galloway DA; et al. Both Rb/p16(INK4a) inactivation and telomerase activity are required to immortalize human epithelial cells | 151 | 494 |
| 29 | 6 | 19 | 364 1965 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 65(1):69-& GIRARDI AJ; JENSEN FC; KOPROWSK.H SV 40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS - CRISIS AND RECOVERY | 150 | 332 |
| 30 | 10 | 24 | 7896 1998 CURRENT BIOLOGY 8(5):279-282 Vaziri H; Benchimol S Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span | 147 | 431 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 6 | 50 | 5828 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(10):3316-3320 RITTLING SR; BROOKS KM; CRISTOFALO VJ; BASERGA R EXPRESSION OF CELL CYCLE-DEPENDENT GENES IN YOUNG AND SENESCENT WI-38 FIBROBLASTS | 146 | 262 |
| 32 | 1 | 4 | 1184 1969 JOURNAL OF CELLULAR PHYSIOLOGY 74(3):219-& MERZ GS; ROSS JD VIABILITY OF HUMAN DIPLOID CELLS AS A FUNCTION OF IN-VITRO AGE | 144 | 159 |
| 33 | 10 | 37 | 7632 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(24):13742-13747 Alcorta DA; Xiong Y; Phelps D; Hannon G; Beach D; et al. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts | 135 | 314 |
| 34 | 2 | 16 | 78 1962 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 110(4):884-& CHANOCK RM; JAMES WD; TURNER HC; HAYFLICK L; FOX HH; et al. GROWTH OF EATON PPLO IN BROTH AND PREPARATION OF COMPLEMENT FIXING ANTIGEN | 133 | 133 |
| 35 | 2 | 29 | 1351 1970 BIOCHIMICA ET BIOPHYSICA ACTA 219(1):104-& ROTTEM S; HUBBELL WL; HAYFLICK L; MCCONNEL.HM MOTION OF FATTY ACID SPIN LABELS IN PLASMA MEMBRANE OF MYCOPLASMA | 133 | 133 |
| 36 | 1 | 9 | 20 1961 EXPERIMENTAL CELL RESEARCH 23(1):14-& HAYFLICK L ESTABLISHMENT OF A LINE (WISH) OF HUMAN AMNION CELLS IN CONTINUOUS CULTIVATION | 131 | 131 |
| 37 | 15 | 19 | 4346 1980 SCIENCE 207(4426):82-84 SMITH JR; WHITNEY RG INTRACLONAL VARIATION IN PROLIFERATIVE POTENTIAL OF HUMAN-DIPLOID FIBROBLASTS - STOCHASTIC MECHANISM FOR CELLULAR AGING | 130 | 185 |
| 38 | 67 | 114 | 7637 1996 SCIENCE 273(5271):63-67 Smith JR; PereiraSmith OM Replicative senescence: Implications for in vivo aging and tumor suppression | 130 | 279 |
| 39 | 20 | 45 | 3738 1978 SCIENCE 202(4373):1158-1163 BELL E; MAREK LF; LEVINSTONE DS; MERRILL C; SHER S; et al. LOSS OF DIVISION POTENTIAL INVITRO - AGING OR DIFFERENTIATION | 126 | 166 |
| 40 | 4 | 19 | 158 1963 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50(2):390-& SAKSELA E; MOORHEAD PS ANEUPLOIDY IN DEGENERATIVE PHASE OF SERIAL CULTIVATION OF HUMAN CELL STRAINS | 125 | 196 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 16 | 35 | 6837 1992 JOURNAL OF MOLECULAR BIOLOGY 225(4):951-960 LEVY MZ; ALLSOPP RC; FUTCHER AB; GREIDER CW; HARLEY CB TELOMERE END-REPLICATION PROBLEM AND CELL AGING | 124 | 371 |
| 42 | 13 | 23 | 7513 1996 CELL 84(4):497-500 Campisi J Replicative senescence: An old lives' tale? | 124 | 222 |
| 43 | 10 | 16 | 3723 1978 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 75(3):1353-1356 SMITH JR; PEREIRASMITH OM; SCHNEIDER EL COLONY SIZE DISTRIBUTIONS AS A MEASURE OF INVIVO AND INVITRO AGING | 122 | 161 |
| 44 | 10 | 25 | 5835 1986 SCIENCE 232(4748):393-395 LUMPKIN CK; MCCLUNG JK; PEREIRASMITH OM; SMITH JR EXISTENCE OF HIGH ABUNDANCE ANTIPROLIFERATIVE MESSENGER-RNAS IN SENESCENT HUMAN-DIPLOID FIBROBLASTS | 122 | 185 |
| 45 | 6 | 27 | 2560 1974 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 71(6):2231-2235 NORWOOD TH; PENDERGR.WR; SPRAGUE CA; MARTIN GM DOMINANCE OF SENESCENT PHENOTYPE IN HETEROKARYONS BETWEEN REPLICATIVE AND POST-REPLICATIVE HUMAN FIBROBLAST-LIKE CELLS | 121 | 164 |
| 46 | 5 | 29 | 2659 1975 CELL 6(3):331-344 RHEINWALD JG; GREEN H SERIAL CULTIVATION OF STRAINS OF HUMAN EPIDERMAL KERATINOCYTES - FORMATION OF KERATINIZING COLONIES FROM SINGLE CELLS | 119 | 2244 |
| 47 | 4 | 47 | 2559 1974 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 71(6):2169-2173 HART RW; SETLOW RB CORRELATION BETWEEN DEOXYRIBONUCLEIC-ACID EXCISION-REPAIR AND LIFE-SPAN IN A NUMBER OF MAMMALIAN-SPECIES | 117 | 524 |
| 48 | 4 | 24 | 3454 1977 SCIENCE 196(4285):60-63 NICHOLS WW; MURPHY DG; CRISTOFALO VJ; TOJI LH; GREENE AE; et al. CHARACTERIZATION OF A NEW HUMAN DIPLOID CELL STRAIN, IMR-90 | 117 | 264 |
| 49 | 7 | 40 | 3040 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(12):3521-3529 BRADLEY MO; HAYFLICK L; SCHIMKE RT PROTEIN DEGRADATION IN HUMAN FIBROBLASTS (WI-38) - EFFECTS OF AGING, VIRAL TRANSFORMATION, AND AMINO-ACID ANALOGS | 114 | 114 |
| 50 | 17 | 46 | 7352 1995 EXPERIMENTAL CELL RESEARCH 220(1):186-193 VONZGLINICKI T; SARETZKI G; DOCKE W; LOTZE C MILD HYPEROXIA SHORTENS TELOMERES AND INHIBITS PROLIFERATION OF FIBROBLASTS - A MODEL FOR SENESCENCE | 114 | 249 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 11 | 65 | 7686 1997 CELL 90(4):785-795 Meyerson M; Counter CM; Eaton EN; Ellisen LW; Steiner P; et al. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | 109 | 839 |
| 52 | 2 | 14 | 3272 1977 EXPERIMENTAL CELL RESEARCH 104(2):255-262 CHEN TR INSITU DETECTION OF MYCOPLASMA CONTAMINATION IN CELL-CULTURES BY FLUORESCENT HOECHST-33258 STAIN | 108 | 1763 |
| 53 | 7 | 18 | 2095 1973 EXPERIMENTAL CELL RESEARCH 77(1-2):356-360 DELLORCO RT; MERTENS JG; KRUSE PF DOUBLING POTENTIAL CALENDAR TIME, AND SENESCENCE OF HUMAN DIPLOID CELLS IN CULTURE | 107 | 150 |
| 54 | 6 | 13 | 2389 1974 EXPERIMENTAL CELL RESEARCH 88(1):95-104 ABSHER PM; ABSHER RG; BARNES WD GENEALOGIES OF CLONES OF DIPLOID FIBROBLASTS - CINEMICROPHOTOGRAPHIC OBSERVATIONS OF CELL-DIVISION PATTERNS IN RELATION TO POPULATION AGE | 106 | 139 |
| 55 | 11 | 45 | 2700 1975 FEDERATION PROCEEDINGS 34(1):9-13 HAYFLICK L CURRENT THEORIES OF BIOLOGICAL AGING | 106 | 106 |
| 56 | 314 | 569 | 5974 1987 MECHANISMS OF AGEING AND DEVELOPMENT 38(1):1-48 STANULISPRAEGER BM CELLULAR SENESCENCE REVISITED - A REVIEW | 105 | 131 |
| 57 | 3 | 15 | 123 1963 JOURNAL OF BACTERIOLOGY 85(6):1261-& TAYLORROBINSON D; SOMERSON NL; CHANOCK RM; TURNER HC SEROLOGICAL RELATIONSHIPS AMONG HUMAN MYCOPLASMAS AS SHOWN BY COMPLEMENT-FIXATION AND GEL DIFFUSION | 104 | 167 |
| 58 | 9 | 24 | 384 1965 JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 191(5):369-& GRAYSTON JT; ALEXANDE.ER; KENNY GE; CLARKE ER; FREMONT JC; et al. MYCOPLASMA PNEUMONIAE INFECTIONS - CLINICAL AND EPIDEMIOLOGIC STUDIES | 104 | 200 |
| 59 | 11 | 27 | 6146 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(14):5112-5116 BAYREUTHER K; RODEMANN HP; HOMMEL R; DITTMANN K; ALBIEZ M; et al. HUMAN-SKIN FIBROBLASTS INVITRO DIFFERENTIATE ALONG A TERMINAL CELL LINEAGE | 104 | 239 |
| 60 | 7 | 22 | 6696 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(13):5635-5639 NING Y; WEBER JL; KILLARY AM; LEDBETTER DH; SMITH JR; et al. GENETIC-ANALYSIS OF INDEFINITE DIVISION IN HUMAN-CELLS - EVIDENCE FOR A CELL SENESCENCE-RELATED GENE(S) ON HUMAN CHROMOSOME-4 | 104 | 192 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 21 | 33 | 3455 1977 SCIENCE 198(4315):366-372 HOLLIDAY R; HUSCHTSCHA LI; TARRANT GM; KIRKWOOD TBL TESTING COMMITMENT THEORY OF CELLULAR AGING | 102 | 136 |
| 62 | 11 | 21 | 6544 1991 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 179(1):528-534 HARA E; TSURUI H; SHINOZAKI A; NAKADA S; ODA K COOPERATIVE EFFECT OF ANTISENSE-RB AND ANTISENSE-P53 OLIGOMERS ON THE EXTENSION OF LIFE-SPAN IN HUMAN-DIPLOID FIBROBLASTS, TIG-1 | 102 | 172 |
| 63 | 14 | 68 | 1381 1970 EXPERIMENTAL GERONTOLOGY 5(4):291-& HAYFLICK L AGING UNDER GLASS | 101 | 101 |
| 64 | 4 | 18 | 1844 1972 EXPERIMENTAL CELL RESEARCH 74(1):187-& WRIGHT WE; HAYFLICK L FORMATION OF ANUCLEATE AND MULTINUCLEATE CELLS IN NORMAL AND SV40 TRANSFORMED WI-38 BY CYTOCHALASIN B | 101 | 101 |
| 65 | 8 | 66 | 5529 1985 EXPERIMENTAL GERONTOLOGY 20(3-4):145-159 HAYFLICK L THEORIES OF BIOLOGICAL AGING | 100 | 100 |
| 66 | 5 | 10 | 1467 1970 NATURE 227(5254):168-& JACOBS JP; JONES CM; BAILLE JP CHARACTERISTICS OF A HUMAN DIPLOID CELL DESIGNATED MRC-5 | 99 | 299 |
| 67 | 16 | 45 | 6219 1989 EXPERIMENTAL CELL RESEARCH 184(1):109-118 SHAY JW; WRIGHT WE QUANTITATION OF THE FREQUENCY OF IMMORTALIZATION OF NORMAL HUMAN-DIPLOID FIBROBLASTS BY SV40 LARGE T-ANTIGEN | 99 | 184 |
| 68 | 8 | 19 | 3734 1978 SCIENCE 199(4330):781-782 GOLDSTEIN S; MOERMAN EJ; SOELDNER JS; GLEASON RE; BARNETT DM CHRONOLOGIC AND PHYSIOLOGIC AGE AFFECT REPLICATIVE LIFE-SPAN OF FIBROBLASTS FROM DIABETIC, PRE-DIABETIC, AND NORMAL DONORS | 97 | 146 |
| 69 | 5 | 15 | 1419 1970 JOURNAL OF EXPERIMENTAL MEDICINE 131(6):1211-& ROBBINS E; LEVINE EM; EAGLE H MORPHOLOGIC CHANGES ACCOMPANYING SENESCENCE OF CULTURED HUMAN DIPLOID CELLS | 95 | 146 |
| 70 | 19 | 41 | 711 1967 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 143(A1):608-& HAYFLICK L; STANBRIDGE E ISOLATION AND IDENTIFICATION OF MYCOPLASMA FROM HUMAN CLINICAL MATERIALS | 92 | 92 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 16 | 53 | 6513 1990 SCIENCE 247(4943):707-710 SUGAWARA O; OSHIMURA M; KOI M; ANNAB LA; BARRETT JC INDUCTION OF CELLULAR SENESCENCE IN IMMORTALIZED CELLS BY HUMAN CHROMOSOME-1 | 92 | 198 |
| 72 | 7 | 13 | 6782 1992 EXPERIMENTAL GERONTOLOGY 27(4):375-382 HARLEY CB; VAZIRI H; COUNTER CM; ALLSOPP RC THE TELOMERE HYPOTHESIS OF CELLULAR AGING | 88 | 199 |
| 73 | 142 | 266 | 7069 1993 PHYSIOLOGICAL REVIEWS 73(3):617-638 CRISTOFALO VJ; PIGNOLO RJ REPLICATIVE SENESCENCE OF HUMAN FIBROBLAST-LIKE CELLS IN CULTURE | 86 | 130 |
| 74 | 38 | 79 | 7706 1997 EUROPEAN JOURNAL OF CANCER 33(5):703-709 Campisi J The biology of replicative senescence | 86 | 168 |
| 75 | 19 | 86 | 6657 1991 MOLECULAR AND CELLULAR BIOLOGY 11(8):3905-3914 MURANO S; THWEATT R; REIS RJS; JONES RA; MOERMAN EJ; et al. DIVERSE GENE-SEQUENCES ARE OVEREXPRESSED IN WERNER SYNDROME FIBROBLASTS UNDERGOING PREMATURE REPLICATIVE SENESCENCE | 85 | 164 |
| 76 | 11 | 32 | 6892 1992 TRENDS IN GENETICS 8(6):193-197 WRIGHT WE; SHAY JW TELOMERE POSITIONAL EFFECTS AND THE REGULATION OF CELLULAR SENESCENCE | 85 | 190 |
| 77 | 13 | 52 | 7450 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(18):8348-8352 ATADJA P; WONG H; GARKAVTSEV I; VEILLETTE C; RIABOWOL K INCREASED ACTIVITY OF P53 IN SENESCING FIBROBLASTS | 84 | 158 |
| 78 | 7 | 15 | 1049 1968 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 60(2):583-& LEVINE EM; THOMAS L; MCGREGOR D; HAYFLICK L; EAGLE H ALTERED NUCLEIC ACID METABOLISM IN HUMAN CELL CULTURES INFECTED WITH MYCOPLASMA | 82 | 81 |
| 79 | 8 | 42 | 1918 1972 JOURNAL OF ULTRASTRUCTURE RESEARCH 39(1-2):43-& LIPETZ J; CRISTOFA.VJ ULTRASTRUCTURAL CHANGES ACCOMPANYING AGING OF HUMAN DIPLOID CELLS IN CULTURE | 82 | 139 |
| 80 | 16 | 50 | 4160 1980 EXPERIMENTAL CELL RESEARCH 127(2):385-396 BUNN CL; TARRANT GM LIMITED LIFESPAN IN SOMATIC-CELL HYBRIDS AND CYBRIDS | 82 | 119 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 16 | 24 | 4611 1981 SOMATIC CELL GENETICS 7(4):411-421 PEREIRASMITH OM; SMITH JR EXPRESSION OF SV40-T-ANTIGEN IN FINITE LIFE-SPAN HYBRIDS OF NORMAL AND SV40-TRANSFORMED FIBROBLASTS | 82 | 113 |
| 82 | 81 | 209 | 1553 1971 BACTERIOLOGICAL REVIEWS 35(2):206-& STANBRIDGE E MYCOPLASMAS AND CELL CULTURES | 81 | 163 |
| 83 | 10 | 36 | 1936 1972 NATURE 239(5371):316-& LEWIS CM; TARRANT GM ERROR THEORY AND AGING IN HUMAN DIPLOID FIBROBLASTS | 81 | 130 |
| 84 | 69 | 123 | 4303 1980 MECHANISMS OF AGEING AND DEVELOPMENT 14(1-2):59-79 HAYFLICK L RECENT ADVANCES IN THE CELL BIOLOGY OF AGING | 80 | 79 |
| 85 | 9 | 20 | 8327 2000 CELL 102(4):407-410 Sherr CJ; DePinho RA Cellular senescence: Mitotic clock or culture shock? | 80 | 208 |
| 86 | 9 | 24 | 402 1965 NATURE 205(4972):713-& HAYFLICK L; KOPROWSK.H DIRECT AGAR ISOLATION OF MYCOPLASMAS FROM HUMAN LEUKAEMIC BONE MARROW | 79 | 78 |
| 87 | 18 | 36 | 7840 1997 SCIENCE 277(5327):831-834 Brown JP; Wei WY; Sedivy JM Bypass of senescence after disruption of p21(CIP1/WAF1) gene in normal diploid human fibroblasts | 79 | 250 |
| 88 | 2 | 43 | 71 1962 PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES 157(966):128-& KROHN PL REVIEW LECTURES ON SENESCENCE .2. HETEROCHRONIC TRANSPLANTATION IN STUDY OF AGEING | 78 | 148 |
| 89 | 14 | 34 | 2116 1973 GERONTOLOGIA 19(5-6):303-313 LEGUILLY Y; SIMON M; LENOIR P; BOUREL M LONG-TERM CULTURE OF HUMAN ADULT LIVER-CELLS - MORPHOLOGICAL CHANGES RELATED TO INVITRO SENESCENCE AND EFFECT OF DONORS AGE ON GROWTH POTENTIAL | 78 | 84 |
| 90 | 12 | 25 | 3598 1978 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 14(11):951-955 BIERMAN EL EFFECT OF DONOR AGE ON INVITRO LIFE-SPAN OF CULTURED HUMAN ARTERIAL SMOOTH-MUSCLE CELLS | 75 | 104 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 46 | 135 | 3205 1977 AMERICAN JOURNAL OF PATHOLOGY 89(2):484-511 MARTIN GM CELLULAR AGING - CLONAL SENESCENCE .1. | 74 | 93 |
| 92 | 18 | 51 | 7346 1995 EXPERIMENTAL CELL RESEARCH 219(1):130-136 ALLSOPP RC; HARLEY CB EVIDENCE FOR A CRITICAL TELOMERE LENGTH IN SENESCENT HUMAN FIBROBLASTS | 74 | 170 |
| 93 | 4 | 28 | 7305 1995 BLOOD 85(9):2315-2320 COUNTER CM; GUPTA J; HARLEY CB; LEBER B; BACCHETTI S TELOMERASE ACTIVITY IN NORMAL LEUKOCYTES AND IN HEMATOLOGIC MALIGNANCIES | 73 | 428 |
| 94 | 15 | 51 | 7938 1998 GENES & DEVELOPMENT 12(19):2997-3007 Zhu JY; Woods D; McMahon M; Bishop JM Senescence of human fibroblasts induced by oncogenic Raf | 73 | 229 |
| 95 | 35 | 59 | 8046 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(18):10614-10619 Cristofalo VJ; Allen RG; Pignolo RJ; Martin BG; Beck JC Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation | 73 | 129 |
| 96 | 10 | 23 | 2985 1976 EXPERIMENTAL CELL RESEARCH 103(2):247-255 ABSHER PM; ABSHER RG CLONAL VARIATION AND AGING OF DIPLOID FIBROBLASTS - CINEMATOGRAPHIC STUDIES OF CELL PEDIGREES | 72 | 104 |
| 97 | 0 | 8 | 5 1956 SCIENCE 124(3232):1147-1148 ROBINSON LB; WICHELHAUSEN RH; ROIZMAN B CONTAMINATION OF HUMAN CELL CULTURES BY PLEUROPNEUMONIALIKE ORGANISMS | 71 | 118 |
| 98 | 8 | 14 | 400 1965 NATURE 205(4967):188-& GIRARDI AJ; HAYFLICK L; LEWIS AM; SOMERSON NL RECOVERY OF MYCOPLASMAS IN STUDY OF HUMAN LEUKAEMIA AND OTHER MALIGNANCIES | 71 | 71 |
| 99 | 15 | 23 | 3981 1979 JOURNALS OF GERONTOLOGY 34(3):328-334 MATSUMURA T; ZERRUDO Z; HAYFLICK L SENESCENT HUMAN-DIPLOID CELLS IN CULTURE - SURVIVAL, DNA-SYNTHESIS AND MORPHOLOGY | 71 | 69 |
| 100 | 20 | 58 | 7426 1995 MOLECULAR AND CELLULAR BIOLOGY 15(9):4745-4753 ROGAN EM; BRYAN TM; HUKKU B; MACLEAN K; CHANG ACM; et al. ALTERATIONS IN P53 AND P16(INK4) EXPRESSION AND TELOMERE LENGTH DURING SPONTANEOUS IMMORTALIZATION OF LI-FRAUMENI SYNDROME FIBROBLASTS | 71 | 178 |
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| 101 | 2 | 7 | 171 1963 SCIENCE 139(354):55-& CLYDE WA HEMOLYSIS IN IDENTIFYING EATONS PLEUROPNEUMONIA-LIKE ORGANISM | 70 | 91 |
| 102 | 5 | 28 | 173 1963 SCIENCE 140(356):662-& CHANOCK RM MYCOPLASMA PNEUMONIAE - PROPOSED NOMENCLATURE FOR ATYPICAL PNEUMONIA ORGANISM (EATON AGENT) | 70 | 85 |
| 103 | 2 | 20 | 6220 1989 EXPERIMENTAL CELL RESEARCH 184(1):138-147 WEST MD; PEREIRASMITH OM; SMITH JR REPLICATIVE SENESCENCE OF HUMAN-SKIN FIBROBLASTS CORRELATES WITH A LOSS OF REGULATION AND OVEREXPRESSION OF COLLAGENASE ACTIVITY | 70 | 111 |
| 104 | 8 | 51 | 7882 1998 CELL 92(3):401-413 van Steensel B; Smogorzewska A; de Lange T TRF2 protects human telomeres from end-to-end fusions | 70 | 467 |
| 105 | 12 | 32 | 2693 1975 EXPERIMENTAL CELL RESEARCH 96(1):113-121 WRIGHT WE; HAYFLICK L NUCLEAR CONTROL OF CELLULAR AGING DEMONSTRATED BY HYBRIDIZATION OF ANUCLEATE AND WHOLE CULTURED NORMAL HUMAN FIBROBLASTS | 69 | 69 |
| 106 | 16 | 79 | 7063 1993 ONCOGENE 8(6):1407-1413 SHAY JW; WRIGHT WE; BRASISKYTE D; VANDERHAEGEN BA E6 OF HUMAN PAPILLOMAVIRUS TYPE-16 CAN OVERCOME THE M1 STAGE OF IMMORTALIZATION IN HUMAN MAMMARY EPITHELIAL-CELLS BUT NOT IN HUMAN FIBROBLASTS | 69 | 192 |
| 107 | 8 | 15 | 405 1965 NATURE 207(4992):43-& PATON GR; JACOBS JP; PERKINS FT CHROMOSOME CHANGES IN HUMAN DIPLOID-CELL CULTURES INFECTED WITH MYCOPLASMA | 68 | 112 |
| 108 | 5 | 14 | 553 1966 JOURNAL OF BACTERIOLOGY 92(1):6-& PURCELL RH; TAYLORRO.D; WONG D; CHANOCK RM COLOR TEST FOR MEASUREMENT OF ANTIBODY TO T-STRAIN MYCOPLASMAS | 68 | 191 |
| 109 | 2 | 3 | 1068 1968 SCIENTIFIC AMERICAN 218(3):32-& HAYFLICK L HUMAN CELLS AND AGING | 68 | 68 |
| 110 | 16 | 29 | 6149 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(23):9086-9090 SHERWOOD SW; RUSH D; ELLSWORTH JL; SCHIMKE RT DEFINING CELLULAR SENESCENCE IN IMR-90 CELLS - A FLOW CYTOMETRIC ANALYSIS | 68 | 100 |
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| 111 | 12 | 31 | 6883 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(1):157-161 RIABOWOL K; SCHIFF J; GILMAN MZ TRANSCRIPTION FACTOR AP-1 ACTIVITY IS REQUIRED FOR INITIATION OF DNA-SYNTHESIS AND IS LOST DURING CELLULAR AGING | 68 | 184 |
| 112 | 7 | 33 | 243 1964 JOURNAL OF GENERAL MICROBIOLOGY 34(2):285-& BUTLER M; LEACH RH MYCOPLASMA WHICH INDUCES ACIDITY + CYTOPATHIC EFFECT IN TISSUE CULTURE | 67 | 80 |
| 113 | 5 | 19 | 427 1965 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 119(1):233-& FOGH J; FOGH H CHROMOSOME CHANGES IN PPLO-INFECTED FL HUMAN AMNION CELLS | 67 | 108 |
| 114 | 3 | 8 | 194 1964 AMERICAN JOURNAL OF HYGIENE 80(1):135-& TAYLORROBINSON D; CHANOCK RM; FOX H; CANCHOLA J NEWLY IDENTIFIED ORAL MYCOPLASMA ( M ORALE ) + ITS RELATIONSHIP TO OTHER HUMAN MYCOPLASMAS | 66 | 82 |
| 115 | 10 | 22 | 786 1967 JOURNAL OF BACTERIOLOGY 93(4):1392-& STANBRIDGE E; HAYFLICK L GROWTH INHIBITION TEST FOR IDENTIFICATION OF MYCOPLASMA SPECIES UTILIZING DRIED ANTISERUM-IMPREGNATED PAPER DISCS | 66 | 66 |
| 116 | 12 | 37 | 7310 1995 CANCER RESEARCH 55(11):2284-2292 WANG E SENESCENT HUMAN FIBROBLASTS RESIST PROGRAMMED CELL-DEATH, AND FAILURE TO SUPPRESS BCL2 IS INVOLVED | 66 | 155 |
| 117 | 1 | 32 | 38 1962 AMERICAN JOURNAL OF HYGIENE 75(2):240-& HAYFLICK L; NORTON TW; PLOTKIN SA; KOPROWSKI H PREPARATION OF POLIOVIRUS VACCINES IN A HUMAN FETAL DIPLOID CELL STRAIN | 65 | 65 |
| 118 | 15 | 24 | 3650 1978 JOURNAL OF CELLULAR PHYSIOLOGY 97(3):509-515 HARLEY CB; GOLDSTEIN S CULTURED HUMAN FIBROBLASTS - DISTRIBUTION OF CELL GENERATIONS AND A CRITICAL LIMIT | 65 | 82 |
| 119 | 0 | 1 | 7166 1994 HOW WHY WE AGE Hayflick L How and Why We Age | 65 | 65 |
| 120 | 8 | 44 | 8112 1999 CELL 97(4):527-538 Chin L; Artandi SE; Shen Q; Tam A; Lee SL; et al. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis | 65 | 278 |
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| 121 | 0 | 1 | 1237 1969 MYCOPLASMATALES L PH Hayflick L The Mycoplasmatales and the L – phase of bacteria | 64 | 64 |
| 122 | 2 | 22 | 4321 1980 NEW ENGLAND JOURNAL OF MEDICINE 303(3):130-135 FRIES JF AGING, NATURAL DEATH, AND THE COMPRESSION OF MORBIDITY | 64 | 839 |
| 123 | 11 | 43 | 8259 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(7):3723-3728 Zhu JY; Wang H; Bishop JM; Blackburn EH Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening | 64 | 193 |
| 124 | 6 | 27 | 3426 1977 NATURE 265(5593):421-424 RHEINWALD JG; GREEN H EPIDERMAL GROWTH-FACTOR AND MULTIPLICATION OF CULTURED HUMAN EPIDERMAL KERATINOCYTES | 63 | 651 |
| 125 | 6 | 17 | 3431 1977 NATURE 270(5635):301-304 KIRKWOOD TBL EVOLUTION OF AGING | 63 | 241 |
| 126 | 12 | 44 | 7523 1996 DEVELOPMENTAL GENETICS 18(2):173-179 Wright WE; Piatyszek MA; Rainey WE; Byrd W; Shay JW Telomerase activity in human germline and embryonic tissues and cells | 63 | 363 |
| 127 | 15 | 39 | 470 1966 AMERICAN JOURNAL OF EPIDEMIOLOGY 84(1):51-& PURCELL RH; TAYLORRO.D; WONG DC; CHANOCK RM A COLOR TEST FOR MEASUREMENT OF ANTIBODY OF NON-ACID-FORMING HUMAN MYCOPLASMA SPECIES | 62 | 144 |
| 128 | 11 | 34 | 7054 1993 MOLECULAR AND CELLULAR BIOLOGY 13(10):6036-6043 OGATA T; AYUSAWA D; NAMBA M; TAKAHASHI E; OSHIMURA M; et al. CHROMOSOME-7 SUPPRESSES INDEFINITE DIVISION OF NONTUMORIGENIC IMMORTALIZED HUMAN FIBROBLAST CELL-LINES KMST-6 AND SUSM-1 | 62 | 115 |
| 129 | 8 | 18 | 7255 1994 ONCOGENE 9(7):1885-1889 BOND JA; WYLLIE FS; WYNFORDTHOMAS D ESCAPE FROM SENESCENCE IN HUMAN-DIPLOID FIBROBLASTS INDUCED DIRECTLY BY MUTANT P53 | 62 | 130 |
| 130 | 7 | 26 | 376 1965 JOURNAL OF IMMUNOLOGY 95(1):19-& KENNY GE; GRAYSTON JT EATON PLEUROPNEUMONIA-LIKE ORGANISM (MYCOPLASMA PNEUMONIAE) COMPLEMENT-FIXING ANTIGEN - EXTRACTION WITH ORGANIC SOLVENTS | 61 | 160 |
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| 131 | 18 | 86 | 411 1965 NEW ENGLAND JOURNAL OF MEDICINE 273(22):1199-& CHANOCK RM MYCOPLASMA INFECTIONS OF MAN | 61 | 131 |
| 132 | 9 | 26 | 2683 1975 EXPERIMENTAL CELL RESEARCH 93(1):184-190 BOWMAN PD; MEEK RL; DANIEL CW AGING OF HUMAN FIBROBLASTS INVITRO - CORRELATIONS BETWEEN DNA SYNTHETIC ABILITY AND CELL-SIZE | 61 | 82 |
| 133 | 18 | 40 | 8619 2001 GENES & DEVELOPMENT 15(4):398-403 Ramirez RD; Morales CP; Herbert BS; Rohde JM; Passons C; et al. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions | 61 | 138 |
| 134 | 1 | 31 | 69 1962 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 48(7):1164-& SHEIN HM; ENDERS JF TRANSFORMATION INDUCED BY SIMIAN VIRUS 40 IN HUMAN RENAL CELL CULTURES, .1. MORPHOLOGY AND GROWTH CHARACTERISTICS | 60 | 254 |
| 135 | 3 | 22 | 84 1963 AMERICAN JOURNAL OF HYGIENE 77(1):122-& SOMERSON NL; CHANOCK RM; TAYLORROBINSON D HEMOLYSIN PRODUCTION AS AN AID IN IDENTIFICATION AND QUANTITATION OF EATON AGENT (MYCOPLASMA PNEUMONIAE) | 60 | 79 |
| 136 | 2 | 24 | 1050 1968 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 61(1):53-& DANIEL CW; DEOME KB; YOUNG JT; BLAIR PB; FAULKIN LJ IN VIVO LIFE SPAN OF NORMAL AND PRENEOPLASTIC MOUSE MAMMARY GLANDS - A SERIAL TRANSPLANTATION STUDY | 60 | 133 |
| 137 | 12 | 33 | 7236 1994 MOLECULAR AND CELLULAR BIOLOGY 14(4):2291-2297 HENSLER PJ; ANNAB LA; BARRETT JC; PEREIRASMITH OM A GENE INVOLVED IN CONTROL OF HUMAN CELLULAR SENESCENCE ON HUMAN CHROMOSOME-1Q | 60 | 92 |
| 138 | 2 | 53 | 11 1960 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 79(10):433-449 HAYFLICK L; STINEBRING WR INTRACELLULAR GROWTH OF PLEUROPNEUMONIALIKE ORGANISMS (PPLO) IN TISSUE CULTURE AND INOVO | 59 | 59 |
| 139 | 7 | 20 | 133 1963 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 62(3):257-& TODARO GJ; WOLMAN SR; GREEN H RAPID TRANSFORMATION OF HUMAN FIBROBLASTS WITH LOW GROWTH POTENTIAL INTO ESTABLISHED CELL LINES BY SV40 | 59 | 107 |
| 140 | 6 | 50 | 244 1964 JOURNAL OF HYGIENE 62(2):199-& LEMCKE RM SEROLOGICAL DIFFERENTIATION OF MYCOPLASMA STRAINS ( PLEUROPNEUMONIA-LIKE ORGANISMS ) FROM VARIOUS SOURCES | 59 | 114 |
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| 141 | 7 | 31 | 370 1965 JOURNAL OF EXPERIMENTAL MEDICINE 121(6):1071-& DAJANI AS; CLYDE WA; DENNY FW EXPERIMENTAL INFECTION WITH MYCOPLASMA PNEUMONIAE (EATONS AGENT) | 59 | 115 |
| 142 | 1 | 25 | 415 1965 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 53(2):350-& LEVINE EM; BECKER Y; BOONE CW; EAGLE H CONTACT INHIBITION MACROMOLECULAR SYNTHESIS AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS | 59 | 286 |
| 143 | 1 | 13 | 766 1967 EXPERIMENTAL CELL RESEARCH 45(2):336-& SIMONS JWI USE OF FREQUENCY DISTRIBUTIONS OF CELL DIAMETERS TO CHARACTERIZE CELL POPULATIONS IN TISSUE CULTURE | 59 | 80 |
| 144 | 1 | 42 | 1676 1971 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 93(2):314-& HUBBELL WL; MCCONNEL.HM MOLECULAR MOTION IN SPIN-LABELED PHOSPHOLIPIDS AND MEMBRANES | 58 | 1531 |
| 145 | 5 | 29 | 2658 1975 CELL 6(2):179-184 SCHNEIDER EL; SHORR SS ALTERATION IN CELLULAR RNAS DURING INVITRO LIFESPAN OF CULTURED HUMAN DIPLOID FIBROBLASTS | 58 | 75 |
| 146 | 10 | 23 | 2775 1975 JOURNAL OF THEORETICAL BIOLOGY 53(2):481-496 KIRKWOOD TBL; HOLLIDAY R COMMITMENT TO SENESCENCE - MODEL FOR FINITE AND INFINITE GROWTH OF DIPLOID AND TRANSFORMED HUMAN FIBROBLASTS IN CULTURE | 58 | 78 |
| 147 | 7 | 25 | 3859 1979 EXPERIMENTAL CELL RESEARCH 120(1):155-165 STEIN GH; YANISHEVSKY RM ENTRY INTO S-PHASE IS INHIBITED IN 2 IMMORTAL CELL-LINES FUSED TO SENESCENT HUMAN-DIPLOID CELLS | 58 | 87 |
| 148 | 9 | 35 | 388 1965 JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 192(13):1146-& MUFSON MA; LUDWIG WM; PURCELL RH; CATE TR; TAYLORRO.D; et al. EXUDATIVE PHARYNGITIS FOLLOWING EXPERIMENTAL MYCOPLASMA HOMINIS TYPE 1 INFECTION | 57 | 86 |
| 149 | 33 | 73 | 1663 1971 JOURNAL OF INFECTIOUS DISEASES 123(1):74-& DENNY FW MYCOPLASMA-PNEUMONIAE DISEASE - CLINICAL SPECTRUM, PATHOPHYSIOLOGY, EPIDEMIOLOGY, AND CONTROL | 57 | 215 |
| 150 | 0 | 1 | 2266 1973 TISSUE CULTURE METHO :220-223 Hayflick L Subculturing human diploid fibroblast cultures. In Tissue Culture: Methods and Applications (PF Kruse Jr & MK Patterson Jr eds.) | 57 | 57 |
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| 151 | 17 | 28 | 4352 1980 SOMATIC CELL GENETICS 6(6):689-698 MUGGLETONHARRIS AL; DESIMONE DW REPLICATIVE POTENTIALS OF VARIOUS FUSION PRODUCTS BETWEEN WI-38 AND SV40-TRANSFORMED WI-38 CELLS AND THEIR COMPONENTS | 57 | 77 |
| 152 | 8 | 21 | 1836 1972 EXPERIMENTAL CELL RESEARCH 70(2):279-& LIMA L; MACIEIRA.A PARAMETERS OF AGING IN CHICKEN EMBRYO FIBROBLASTS CULTIVATED IN-VITRO | 56 | 77 |
| 153 | 23 | 79 | 2433 1974 INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY 24(2):160-171 SHEPARD MC; LUNCEFOR.CD; FORD DK; PURCELL RH; TAYLORRO.D; et al. UREAPLASMA-UREALYTICUM GEN-NOV, SP-NOV - PROPOSED NOMENCLATURE FOR HUMAN-T (T-STRAIN) MYCOPLASMAS | 56 | 170 |
| 154 | 11 | 28 | 2748 1975 JOURNAL OF CELL BIOLOGY 64(3):551-556 NORWOOD TH; PENDERGRASS WR; MARTIN GM REINITIATION OF DNA-SYNTHESIS IN SENESCENT HUMAN FIBROBLASTS UPON FUSION WITH CELLS OF UNLIMITED GROWTH POTENTIAL | 56 | 81 |
| 155 | 22 | 183 | 7479 1996 ANNUAL REVIEW OF BIOCHEMISTRY 65:337-365 Greider CW Telomere length regulation | 56 | 490 |
| 156 | 3 | 27 | 52 1962 JOURNAL OF BACTERIOLOGY 84(1):130-& BARILE MF; RIGGS DB; MALIZIA WF INCIDENCE AND DETECTION OF PLEUROPNEUMONIA-LIKE ORGANISMS IN CELL CULTURES BY FLUORESCENT ANTIBODY AND CULTURAL PROCEDURES | 55 | 85 |
| 157 | 0 | 25 | 2268 1973 TRANSPLANTATION PROCEEDINGS 5(1):707-710 SUMMERLIN WT; BROUTBAR C; FOANES RB; PAYNE R; STUTMAN O; et al. ACCEPTANCE OF PHENOTYPICALLY DIFFERING CULTURED SKIN IN MAN AND MICE | 55 | 55 |
| 158 | 11 | 29 | 2882 1976 AMERICAN JOURNAL OF HUMAN GENETICS 28(5):465-473 BENN PA SPECIFIC CHROMOSOME-ABERRATIONS IN SENESCENT FIBROBLAST CELL LINES DERIVED FROM HUMAN EMBRYOS | 55 | 143 |
| 159 | 15 | 44 | 6966 1993 EXPERIMENTAL CELL RESEARCH 209(2):231-237 AFSHARI CA; VOJTA PJ; ANNAB LA; FUTREAL PA; WILLARD TB; et al. INVESTIGATION OF THE ROLE OF G(1)/S CELL-CYCLE MEDIATORS IN CELLULAR SENESCENCE | 55 | 81 |
| 160 | 1 | 15 | 73 1962 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 110(3):543-& CHANOCK RM; MUFSON MA; JAMES WD; BLOOM HH; FORSYTH B; et al. RECOVERY OF PPLO OF ATYPICAL PNEUMONIA ON ARTIFICIAL AGAR MEDIUM | 54 | 78 |
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| 161 | 4 | 25 | 398 1965 LANCET 2(7409):418-& KAY HEM HOW MANY CELL-GENERATIONS | 54 | 153 |
| 162 | 31 | 86 | 1843 1972 EXPERIMENTAL CELL RESEARCH 74(1):99-& LEVINE EM MYCOPLASMA CONTAMINATION OF ANIMAL CELL-CULTURES - SIMPLE, RAPID DETECTION METHOD | 54 | 186 |
| 163 | 11 | 27 | 2987 1976 EXPERIMENTAL CELL RESEARCH 103(2):321-330 MUGGLETONHARRIS AL; HAYFLICK L CELLULAR AGING STUDIED BY RECONSTRUCTION OF REPLICATING CELLS FROM NUCLEI AND CYTOPLASMS ISOLATED FROM NORMAL HUMAN DIPLOID CELLS | 54 | 54 |
| 164 | 6 | 11 | 4155 1980 EXPERIMENTAL CELL RESEARCH 126(2):469-472 YANISHEVSKY RM; STEIN GH ONGOING DNA-SYNTHESIS CONTINUES IN YOUNG HUMAN-DIPLOID CELLS (HDC) FUSED TO SENESCENT HDC, BUT ENTRY INTO S-PHASE IS INHIBITED | 54 | 73 |
| 165 | 0 | 0 | 4349 1980 SCIENTIFIC AMERICAN 242(1):58-65 HAYFLICK L CELL BIOLOGY OF HUMAN AGING | 54 | 54 |
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| 167 | 5 | 11 | 2382 1974 EXPERIMENTAL CELL RESEARCH 84(1-2):363-366 DELLORCO RT; MERTENS JG; KRUSE PF DOUBLING POTENTIAL, CALENDAR TIME, AND DONOR AGE OF HUMAN DIPLOID CELLS IN CULTURE | 53 | 61 |
| 168 | 14 | 57 | 2492 1974 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 22(1):1-12 HAYFLICK L LONGEVITY OF CULTURED HUMAN CELLS | 53 | 53 |
| 169 | 6 | 24 | 2970 1976 EXPERIMENTAL CELL RESEARCH 98(2):298-302 SCHNEIDER EL; FOWLKES BJ MEASUREMENT OF DNA CONTENT AND CELL-VOLUME IN SENESCENT HUMAN FIBROBLASTS UTILIZING FLOW MULTIPARAMETER SINGLE CELL ANALYSIS | 53 | 73 |
| 170 | 10 | 46 | 5987 1987 MOLECULAR AND CELLULAR BIOLOGY 7(8):2794-2802 NEUFELD DS; RIPLEY S; HENDERSON A; OZER HL IMMORTALIZATION OF HUMAN-FIBROBLASTS TRANSFORMED BY ORIGIN-DEFECTIVE SIMIAN VIRUS-40 | 53 | 103 |
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| 173 | 8 | 25 | 5050 1983 JOURNAL OF CELLULAR PHYSIOLOGY 114(3):311-316 PHILLIPS PD; KUHNLE E; CRISTOFALO VJ [I-125]-LABELED EGF BINDING ABILITY IS STABLE THROUGHOUT THE REPLICATIVE LIFE-SPAN OF WI-38 CELLS | 52 | 79 |
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| 176 | 5 | 13 | 2228 1973 NATURE 245(5424):316-319 HOLLAND JJ; KOHNE D; DOYLE MV ANALYSIS OF VIRUS REPLICATION IN AGING HUMAN FIBROBLAST CULTURES | 51 | 65 |
| 177 | 7 | 29 | 3145 1976 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 73(8):2818-2822 LINN S; KAIRIS M; HOLLIDAY R DECREASED FIDELITY OF DNA-POLYMERASE ACTIVITY ISOLATED FROM AGING HUMAN FIBROBLASTS | 51 | 147 |
| 178 | 0 | 1 | 4075 1980 ANN REV GERONTOLOGY 1:26-67 Hayflick L Cell Aging. In Annual Review of Gerontology and Geriatrics (ed. C. Eisdorfer) | 51 | 51 |
| 179 | 10 | 53 | 5573 1985 JOURNAL OF CELLULAR PHYSIOLOGY 125(1):122-126 GORMAN SD; CRISTOFALO VJ REINITIATION OF CELLULAR DNA-SYNTHESIS IN BRDU-SELECTED NONDIVIDING SENESCENT WI-38 CELLS BY SIMIAN VIRUS-40 INFECTION | 51 | 68 |
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| 181 | 8 | 31 | 484 1966 ANNALES MEDICINAE EXPERIMENTALIS ET BIOLOGIAE FENNIAE 44(2):242-& GIRARDI AJ; WEINSTEI.D; MOORHEAD PS SV40 TRANSFORMATION OF HUMAN DIPLOID CELLS - APARALLEL STUDY OF VIRAL AND KARYOLOGIC PARAMETERS | 50 | 103 |
| 182 | 19 | 36 | 1150 1969 EXPERIMENTAL CELL RESEARCH 57(2-3):397-& STANBRIDGE E; ONEN M; PERKINS FT; HAYFLICK L KARYOLOGICAL AND MORPHOLOGICAL CHARACTERISTICS OF HUMAN DIPLOID CELL STRAIN WI-38 INFECTED WITH MYCOPLASMAS | 50 | 50 |
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| 184 | 11 | 43 | 4165 1980 EXPERIMENTAL CELL RESEARCH 130(1):101-109 RABINOVITCH PS; NORWOOD TH COMPARATIVE HETEROKARYON STUDY OF CELLULAR SENESCENCE AND THE SERUM-DEPRIVED STATE | 50 | 101 |
| 185 | 11 | 21 | 7897 1998 CURRENT BIOLOGY 8(6):351-354 McConnell BB; Starborg M; Brookes S; Peters G Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts | 50 | 100 |
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| 188 | 7 | 23 | 4772 1982 JOURNAL OF BACTERIOLOGY 151(3):1514-1522 BASEMAN JB; COLE RM; KRAUSE DC; LEITH DK MOLECULAR-BASIS FOR CYTADSORPTION OF MYCOPLASMA-PNEUMONIAE | 49 | 145 |
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| 190 | 3 | 13 | 279 1964 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 116(4):947-& DOWDLE WR; ROBINSON RQ INDIRECT HEMAGGLUTINATION TEST FOR DIAGNOSIS OF MYCOPLASMA PNEUMONIAE INFECTIONS | 48 | 75 |
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| 191 | 3 | 4 | 701 1967 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 143(A1):384-& SOMERSON NL; JAMES WD; WALLS BE; CHANOCK RM GROWTH OF MYCOPLASMA PNEUMONIAE ON A GLASS SURFACE | 48 | 90 |
| 192 | 3 | 16 | 1725 1971 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 137(1):331-& HOUCK JC; SHARMA VK; HAYFLICK L FUNCTIONAL FAILURES OF CULTURED HUMAN DIPLOID FIBROBLASTS AFTER CONTINUED POPULATION DOUBLINGS | 48 | 48 |
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| 198 | 6 | 23 | 2251 1973 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70(11):3184-3188 HARRISON DE NORMAL PRODUCTION OF ERYTHROCYTES BY MOUSE MARROW CONTINUOUS FOR 73 MONTHS | 47 | 109 |
| 199 | 12 | 34 | 2692 1975 EXPERIMENTAL CELL RESEARCH 96(1):103-112 BRADLEY MO; DICE JF; HAYFLICK L; SCHIMKE RT PROTEIN ALTERATIONS IN AGING WI38-CELLS AS DETERMINED BY PROTEOLYTIC SUSCEPTIBILITY | 47 | 47 |
| 200 | 3 | 18 | 2780 1975 JOURNALS OF GERONTOLOGY 30(3):279-285 HARRISON DE NORMAL FUNCTION OF TRANSPLANTED MARROW CELL LINES FROM AGED MICE | 47 | 84 |
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| 203 | 1 | 83 | 7313 1995 CELL 81(3):323-330 WEINBERG RA THE RETINOBLASTOMA PROTEIN AND CELL-CYCLE CONTROL | 47 | 2509 |
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| 206 | 4 | 13 | 169 1963 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 114(3):676-& BARILE MF; SCHIMKE RT A RAPID CHEMICAL METHOD FOR DETECTING PPLO CONTAMINATION OF TISSUE CELL CULTURES | 46 | 100 |
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| 208 | 6 | 18 | 1588 1971 EXPERIMENTAL CELL RESEARCH 65(1):27-& DANIEL CW; YOUNG LJT INFLUENCE OF CELL DIVISION ON AN AGING PROCESS - LIFE SPAN OF MOUSE MAMMARY EPITHELIUM DURING SERIAL PROPAGATION IN-VIVO | 46 | 60 |
| 209 | 6 | 18 | 1619 1971 INFECTION AND IMMUNITY 3(5):694-& COLLIER AM; CLYDE WA RELATIONSHIPS BETWEEN MYCOPLASMA-PNEUMONIAE AND HUMAN RESPIRATORY EPITHELIUM | 46 | 136 |
| 210 | 14 | 40 | 2097 1973 EXPERIMENTAL CELL RESEARCH 79(1):1-14 BRUNK U; ERICSSON JL; PONTEN J; WESTERMA.B RESIDUAL BODIES AND AGING IN CULTURED HUMAN GLIA CELLS - EFFECT OF ENTRANCE INTO PHASE III AND PROLONGED PERIODS OF CONFLUENCE | 46 | 89 |
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| 211 | 7 | 469 | 2889 1976 ANNUAL REVIEW OF BIOCHEMISTRY 45:747-803 GOLDBERG AL; STJOHN AC INTRACELLULAR PROTEIN DEGRADATION IN MAMMALIAN AND BACTERIAL-CELLS .2. | 46 | 1206 |
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| 213 | 87 | 238 | 7136 1994 CRITICAL REVIEWS IN ONCOGENESIS 5(4):331-357 BRYAN TM; REDDEL RR SV40-INDUCED IMMORTALIZATION OF HUMAN-CELLS | 46 | 116 |
| 214 | 13 | 35 | 8485 2000 NATURE MEDICINE 6(8):849-851 Wright WE; Shay JW Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology | 46 | 119 |
| 215 | 1 | 8 | 868 1967 SCIENCE 157(3796):1573-& KUNDSIN RB; DRISCOLL SG; MING PML STRAIN OF MYCOPLASMA ASSOCIATED WITH HUMAN REPRODUCTIVE FAILURE | 45 | 116 |
| 216 | 1 | 27 | 1378 1970 EXPERIMENTAL CELL RESEARCH 61(2-3):357-& WANG KM; ROSE NR; BARTHOLO.EA; BALZER M; BERDE K; et al. CHANGES OF ENZYMIC ACTIVITIES IN HUMAN DIPLOID CELL LINE WI-38 AT VARIOUS PASSAGES | 45 | 59 |
| 217 | 4 | 32 | 1628 1971 JOURNAL OF BACTERIOLOGY 105(1):323-& ROTTEM S; PFENDT EA; HAYFLICK L STEROL REQUIREMENTS OF T-STRAIN MYCOPLASMAS | 45 | 45 |
| 218 | 1 | 38 | 1682 1971 JOURNAL OF THEORETICAL BIOLOGY 33(3):429-& STREHLER B; HIRSCH G; GUSSECK D; JOHNSON R; BICK M CONDON-RESTRICTION THEORY OF AGING AND DEVELOPMENT | 45 | 91 |
| 219 | 5 | 16 | 2532 1974 NATURE 251(5474):434-436 PETES TD; FARBER RA; TARRANT GM; HOLLIDAY R ALTERED RATE OF DNA-REPLICATION IN AGING HUMAN FIBROBLAST-CULTURES | 45 | 71 |
| 220 | 7 | 17 | 2689 1975 EXPERIMENTAL CELL RESEARCH 96(1):1-6 THOMPSON KVA; HOLLIDAY R CHROMOSOME CHANGES DURING INVITRO AGING OF MRC-5 HUMAN FIBROBLASTS | 45 | 66 |
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| 221 | 2 | 26 | 2969 1976 EXPERIMENTAL CELL RESEARCH 97(2):340-345 PELLEGRINO MA; FERRONE S; BRAUTBAR C; HAYFLICK L CHANGES IN HL-A ANTIGEN PROFILES ON SV40-TRANSFORMED HUMAN FIBROBLASTS | 45 | 45 |
| 222 | 6 | 19 | 2977 1976 EXPERIMENTAL CELL RESEARCH 100(1):147-152 MITSUI Y; SCHNEIDER EL INCREASED NUCLEAR SIZES IN SENESCENT HUMAN DIPLOID FIBROBLAST-CULTURES | 45 | 58 |
| 223 | 6 | 19 | 5563 1985 JOURNAL OF CELL BIOLOGY 100(2):545-551 WANG E A 57,000-MOL-WT PROTEIN UNIQUELY PRESENT IN NONPROLIFERATING CELLS AND SENESECENT HUMAN-FIBROBLASTS | 45 | 126 |
| 224 | 4 | 31 | 888 1968 ACTA PATHOLOGICA ET MICROBIOLOGICA SCANDINAVICA 74(4):465-& PONTEN J; MACINTYR.EH LONG TERM CULTURE OF NORMAL AND NEOPLASTIC HUMAN GLIA | 44 | 437 |
| 225 | 43 | 72 | 6662 1991 MUTATION RESEARCH 256(2-6):69-80 HAYFLICK L AGING UNDER GLASS | 44 | 43 |
| 226 | 26 | 91 | 7609 1996 MOLECULAR AND CELLULAR BIOLOGY 16(9):5210-5218 Ogryzko VV; Hirai TH; Russanova VR; Barbie DA; Howard BH Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent | 44 | 92 |
| 227 | 8 | 34 | 951 1968 EXPERIMENTAL GERONTOLOGY 3(1):35-& HAY RJ; MENZIES RA; MORGAN HP; STREHLER BL DIVISION POTENTIAL OF CELLS IN CONTINUOUS GROWTH AS COMPARED TO CELLS SUBCULTIVATED AFTER MAINTENANCE IN STATIONARY PHASE | 43 | 46 |
| 228 | 13 | 67 | 1971 1972 SCIENCE 178(4059):357-& GELFANT S; SMITH JG AGING - NONCYCLING CELLS AN EXPLANATION | 43 | 114 |
| 229 | 14 | 54 | 4988 1983 EXPERIMENTAL CELL RESEARCH 149(2):547-554 OLASHAW NE; KRESS ED; CRISTOFALO VJ THYMIDINE TRIPHOSPHATE SYNTHESIS IN SENESCENT W138 CELLS - RELATIONSHIP TO LOSS OF REPLICATIVE CAPACITY | 43 | 58 |
| 230 | 4 | 44 | 5122 1983 NATURE 306(5943):617-620 CARLIN CR; PHILLIPS PD; KNOWLES BB; CRISTOFALO VJ DIMINISHED INVITRO TYROSINE KINASE-ACTIVITY OF THE EGF RECEPTOR OF SENESCENT HUMAN-FIBROBLASTS | 43 | 87 |
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| 231 | 37 | 80 | 7669 1997 BIOCHEMISTRY-MOSCOW 62(11):1180-1190 Hayflick L Mortality and immortality at the cellular level. A review | 43 | 43 |
| 232 | 1 | 3 | 216 1964 BRITISH MEDICAL JOURNAL 2(541):1263-& GRIST NR; FALLON RJ ISOLATION OF VIRUSES FROM LEUKAEMIC PATIENTS | 42 | 48 |
| 233 | 2 | 42 | 395 1965 JOURNAL OF THE NATIONAL CANCER INSTITUTE 35(4):641-& BERWALD Y; SACHS L IN VITRO TRANSFORMATION OF NORMAL CELLS TO TUMOR CELLS BY CARCINOGENIC HYDROCARBONS | 42 | 488 |
| 234 | 12 | 29 | 973 1968 JOURNAL OF GENERAL MICROBIOLOGY 50:465-& MANCHEE RJ; TAYLORRO.D HAEMADSORPTION AND HAEMAGGLUTINATION BY MYCOPLASMAS | 42 | 175 |
| 235 | 1 | 33 | 1241 1969 NATURE 221(5187):1224-& HOLLIDAY R ERRORS IN PROTEIN SYNTHESIS AND CLONAL SENESCENCE IN FUNGI | 42 | 89 |
| 236 | 5 | 58 | 6366 1990 BIOESSAYS 12(8):363-369 GREIDER CW TELOMERES, TELOMERASE AND SENESCENCE | 42 | 128 |
| 237 | 18 | 100 | 6519 1990 SCIENCE 249(4976):1570-1574 MAIER JAM; VOULALAS P; ROEDER D; MACIAG T EXTENSION OF THE LIFE-SPAN OF HUMAN ENDOTHELIAL-CELLS BY AN INTERLEUKIN-1-ALPHA ANTISENSE OLIGOMER | 42 | 297 |
| 238 | 19 | 35 | 6570 1991 EXPERIMENTAL CELL RESEARCH 195(1):13-19 KUMAZAKI T; ROBETORYE RS; ROBETORYE SC; SMITH JR FIBRONECTIN EXPRESSION INCREASES DURING INVITRO CELLULAR SENESCENCE - CORRELATION WITH INCREASED CELL AREA | 42 | 77 |
| 239 | 19 | 72 | 7339 1995 EXPERIMENTAL CELL RESEARCH 217(2):336-345 KULJU KS; LEHMAN JM INCREASED P53 PROTEIN ASSOCIATED WITH AGING IN HUMAN-DIPLOID FIBROBLASTS | 42 | 72 |
| 240 | 43 | 90 | 8045 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(16):9078-9081 Sedivy JM Can ends justify the means? Telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells | 42 | 106 |
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| 241 | 4 | 11 | 157 1963 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 50(2):343-& JENSEN F; KOPROWSKI H; PONTEN JA RAPID TRANSFORMATION OF HUMAN FIBROBLAST CULTURES BY SIMIAN VIRUS 40 | 41 | 76 |
| 242 | 2 | 14 | 212 1964 BRITISH MEDICAL JOURNAL 1(537):142-& JANSSON E; STENSTROM R; WAGER O; FORSSELL P; KLEMOLA E STUDIES ON EATON PPLO PNEUMONIA | 41 | 77 |
| 243 | 5 | 24 | 235 1964 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 187(6):442-& COUCH RB; CATE TR; CHANOCK RM INFECTION WITH ARTIFICIALLY PROPAGATED EATON AGENT ( MYCOPLASMA PNEUMONIAE ) IMPLICATIONS FOR DEVELOPMENT OF ATTENUATED VACCINE FOR COLD AGGLUTININ-POSITIVE PNEUMONIA | 41 | 75 |
| 244 | 2 | 15 | 363 1965 JOURNAL OF CELL BIOLOGY 27(2):273-& KRUSE PF; MIEDEMA E PRODUCTION AND CHARACTERIZATION OF MULTIPLE-LAYERED POPULATIONS OF ANIMAL CELLS | 41 | 141 |
| 245 | 10 | 53 | 412 1965 NEW ENGLAND JOURNAL OF MEDICINE 273(23):1257-& CHANOCK RM MYCOPLASMA INFECTIONS OF MAN (CONCLUDED) | 41 | 82 |
| 246 | 2 | 22 | 853 1967 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 58(3):1104-& WEISS MC; GREEN H HUMAN-MOUSE HYBRID CELL LINES CONTAINING PARTIAL COMPLEMENTS OF HUMAN CHROMOSOMES AND FUNCTIONING HUMAN GENES | 41 | 503 |
| 247 | 5 | 17 | 1646 1971 JOURNAL OF CLINICAL INVESTIGATION 50(9):2000-& DANES BS PROGERIA - CELL CULTURE STUDY ON AGING | 41 | 81 |
| 248 | 8 | 44 | 1683 1971 JOURNAL OF ULTRASTRUCTURE RESEARCH 36(3-4):291-& BROCK MA; HAY RJ COMPARATIVE ULTRASTRUCTURE OF CHICK FIBROBLASTS IN-VITRO AT EARLY AND LATE STAGES DURING THEIR GROWTH SPAN | 41 | 69 |
| 249 | 9 | 36 | 1847 1972 EXPERIMENTAL CELL RESEARCH 75(1):31-& BRAUTBAR C; PAYNE R; HAYFLICK L FATE OF HL-A ANTIGENS IN AGING CULTURED HUMAN DIPLOID CELL STRAINS | 41 | 41 |
| 250 | 12 | 24 | 5572 1985 JOURNAL OF CELLULAR PHYSIOLOGY 125(1):36-44 STEIN GH SV40-TRANSFORMED HUMAN-FIBROBLASTS - EVIDENCE FOR CELLULAR AGING IN PRECRISIS CELLS | 41 | 67 |
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| 251 | 15 | 30 | 5831 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(23):9030-9034 STEIN GH; ATKINS L MEMBRANE-ASSOCIATED INHIBITOR OF DNA-SYNTHESIS IN SENESCENT HUMAN-DIPLOID FIBROBLASTS - CHARACTERIZATION AND COMPARISON TO QUIESCENT CELL INHIBITOR | 41 | 81 |
| 252 | 9 | 45 | 6095 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(23):11431-11435 CHANG ZF; CHEN KY REGULATION OF ORNITHINE DECARBOXYLASE AND OTHER CELL CYCLE-DEPENDENT GENES DURING SENESCENCE OF IMR-90 HUMAN-DIPLOID FIBROBLASTS | 41 | 63 |
| 253 | 13 | 44 | 7826 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(18):9648-9653 Sugrue MM; Shin DY; Lee SW; Aaronson SA Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53 | 41 | 129 |
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| 255 | 14 | 23 | 357 1965 JOURNAL OF BACTERIOLOGY 90(2):418-& ARMSTRONG D; HENLE G; SOMERSON NL; HAYFLICK L CYTOPATHOGENIC MYCOPLASMAS ASSOCIATED WITH 2 HUMAN TUMORS .I. ISOLATION AND BIOLOGICAL ASPECTS | 40 | 40 |
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| 257 | 8 | 19 | 5246 1984 EXPERIMENTAL CELL RESEARCH 150(2):321-328 IDE T; TSUJI Y; NAKASHIMA T; ISHIBASHI S PROGRESS OF AGING IN HUMAN-DIPLOID CELLS TRANSFORMED WITH A TSA MUTANT OF SIMIAN VIRUS-40 | 40 | 62 |
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| 260 | 11 | 19 | 7439 1995 ONCOGENE 10(5):835-840 TAHARA H; SATO E; NODA A; IDE T INCREASE IN EXPRESSION LEVEL OF P21(SDI1/CIP1/WAF1) WITH INCREASING DIVISION AGE IN BOTH NORMAL AND SV40-TRANSFORMED HUMAN FIBROBLASTS | 40 | 84 |
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| 261 | 16 | 42 | 7548 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):295-301 Vaziri H; Benchimol S From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: The telomere loss DNA damage model of cell aging | 40 | 79 |
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| 263 | 15 | 29 | 545 1966 JOURNAL OF BACTERIOLOGY 91(3):934-& LEACH RH; BUTLER M COMPARISON OF MYCOPLASMAS ASSOCIATED WITH HUMAN TUMORS LEUKEMIA AND TISSUE CULTURES | 39 | 43 |
| 264 | 5 | 10 | 1272 1969 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 131(4):1163-& LIPMAN RP; CLYDE WA INTERRELATIONSHIP OF VIRULENCE, CYTADSORPTION, AND PEROXIDE FORMATION IN MYCOPLASMA PNEUMONIAE | 39 | 61 |
| 265 | 5 | 27 | 2701 1975 FEDERATION PROCEEDINGS 34(1):51-55 HOLLIDAY R GROWTH AND DEATH OF DIPLOID AND TRANSFORMED HUMAN FIBROBLASTS | 39 | 49 |
| 266 | 10 | 25 | 3064 1976 JOURNAL OF CLINICAL MICROBIOLOGY 3(6):613-625 SHEPARD MC; LUNCEFORD CD DIFFERENTIAL AGAR MEDIUM (A7) FOR IDENTIFICATION OF UREAPLASMA-UREALYTICUM (HUMAN T-MYCOPLASMAS) IN PRIMARY CULTURES OF CLINICAL MATERIAL | 39 | 222 |
| 267 | 6 | 32 | 3108 1976 MECHANISMS OF AGEING AND DEVELOPMENT 5(1):67-77 HART RW; SETLOW RB DNA-REPAIR IN LATE-PASSAGE HUMAN CELLS | 39 | 94 |
| 268 | 6 | 9 | 3412 1977 MECHANISMS OF AGEING AND DEVELOPMENT 6(4):283-286 SMITH JR; PEREIRASMITH O; GOOD PI COLONY SIZE DISTRIBUTION AS A MEASURE OF AGE IN CULTURED HUMAN CELLS - BRIEF NOTE | 39 | 46 |
| 269 | 3 | 8 | 3427 1977 NATURE 267(5610):423-425 PACKER L; FUEHR K LOW OXYGEN CONCENTRATION EXTENDS LIFESPAN OF CULTURED HUMAN DIPLOID CELLS | 39 | 112 |
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| 271 | 9 | 25 | 4782 1982 JOURNAL OF CELL BIOLOGY 94(1):187-192 BURMER GC; ZEIGLER CJ; NORWOOD TH EVIDENCE FOR ENDOGENOUS POLYPEPTIDE-MEDIATED INHIBITION OF CELL-CYCLE TRANSIT IN HUMAN-DIPLOID CELLS | 39 | 49 |
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| 274 | 41 | 106 | 8365 2000 EXPERIMENTAL GERONTOLOGY 35(8):927-945 Toussaint O; Medrano EE; von Zglinicki T Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes | 39 | 73 |
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| 276 | 7 | 19 | 359 1965 JOURNAL OF BACTERIOLOGY 90(2):517-& HUMMELER K; TOMASSIN.N; HAYFLICK L ULTRASTRUCTURE OF A MYCOPLASMA (NEGRONI) ISOLATED FROM HUMAN LEUKEMIA | 38 | 38 |
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| 283 | 6 | 20 | 5557 1985 INTERNATIONAL JOURNAL OF CANCER 35(2):275-280 NAMBA M; NISHITANI K; HYODOH F; FUKUSHIMA F; KIMOTO T NEOPLASTIC TRANSFORMATION OF HUMAN-DIPLOID FIBROBLASTS (KMST-6) BY TREATMENT WITH CO-60 GAMMA-RAYS | 38 | 114 |
| 284 | 7 | 44 | 7012 1993 JOURNAL OF CELL SCIENCE 105:123-133 LUCIBELLO FC; SEWING A; BRUSSELBACH S; BURGER C; MULLER R DEREGULATION OF CYCLIN-D1 AND CYCLIN-E AND SUPPRESSION OF CDK2 AND CDK4 IN SENESCENT HUMAN FIBROBLASTS | 38 | 109 |
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| 286 | 4 | 25 | 337 1965 CANCER 18(10):1369-& GRACE JT; HOROSZEW.JS; STIM TB; MIRAND EA; JAMES C MYCOPLASMAS (PPLO) AND HUMAN LEUKEMIA AND LYMPHOMA | 37 | 45 |
| 287 | 11 | 27 | 589 1966 JOURNAL OF THE NATIONAL CANCER INSTITUTE 36(1):155-& BARILE MF; BODEY GP; SNYDER J; RIGGS DB; GRABOWSK.MW ISOLATION OF MYCOPLASMA ORALE FROM LEUKEMIC BONE MARROW AND BLOOD BY DIRECT CULTURE | 37 | 65 |
| 288 | 11 | 35 | 2657 1975 CELL 6(1):67-73 FULDER SJ; HOLLIDAY R RAPID RISE IN CELL VARIANTS DURING SENESCENCE OF POPULATIONS OF HUMAN FIBROBLASTS | 37 | 59 |
| 289 | 8 | 30 | 3172 1976 TRANSPLANTATION 22(3):287-293 OGDEN DA; MICKLEM HS FATE OF SERIALLY TRANSPLANTED BONE-MARROW CELL-POPULATIONS FROM YOUNG AND OLD DONORS | 37 | 91 |
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 291 | 35 | 83 | 6612 1991 JOURNAL OF CELLULAR BIOCHEMISTRY 45(2):147-155 PEACOCKE M; CAMPISI J CELLULAR SENESCENCE - A REFLECTION OF NORMAL GROWTH-CONTROL, DIFFERENTIATION, OR AGING | 37 | 61 |
| 292 | 14 | 23 | 7384 1995 JAPANESE JOURNAL OF CANCER RESEARCH 86(10):899-904 OHMURA H; TAHARA H; SUZUKI M; IDE T; SHIMIZU M; et al. RESTORATION OF THE CELLULAR SENESCENCE PROGRAM AND REPRESSION OF TELOMERASE BY HUMAN-CHROMOSOME-3 | 37 | 104 |
| 293 | 19 | 77 | 8464 2000 MOLECULAR AND CELLULAR BIOLOGY 20(1):273-285 Dimri GP; Itahana K; Acosta M; Campisi J Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor | 37 | 114 |
| 294 | 4 | 37 | 267 1964 NATURE 203(495):1355-& STOKER M; MACPHERSON I SYRIAN HAMSTER FIBROBLAST CELL LINE BHK21 + ITS DERIVATIVES | 36 | 391 |
| 295 | 3 | 9 | 442 1965 SCIENCE 149(3688):1100-& NARDONE RM; TODD J; GONZALEZ P; GAFFNEY EV NUCLEOSIDE INCORPORATION INTO STRAIN L CELLS - INHIBITION BY PLEUROPNEUMONIA-LIKE ORGANISMS | 36 | 83 |
| 296 | 8 | 19 | 2567 1974 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 146(2):385-390 TOMKINS GA; STANBRIDGE EJ; HAYFLICK L VIRAL PROBES OF AGING IN HUMAN DIPLOID CELL STRAIN WI-38 | 36 | 36 |
| 297 | 12 | 41 | 2619 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 170(1):1-11 SUN AS; AGGARWAL BB; PACKER L ENZYME LEVELS OF NORMAL HUMAN CELLS - AGING IN CULTURE | 36 | 67 |
| 298 | 7 | 10 | 2679 1975 EXPERIMENTAL CELL RESEARCH 91(2):389-392 RYAN JM; SHARF BB; CRISTOFALO VJ INFLUENCE OF CULTURE MEDIUM VOLUME ON CELL DENSITY AND LIFESPAN OF HUMAN DIPLOID FIBROBLASTS | 36 | 56 |
| 299 | 1 | 25 | 3589 1978 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 14(2):165-173 MONTGOMERY POB; COOK JE; REYNOLDS RC; PAUL JS; HAYFLICK L; et al. RESPONSE OF SINGLE HUMAN CELLS TO ZERO GRAVITY | 36 | 36 |
| 300 | 25 | 45 | 3957 1979 JOURNAL OF INVESTIGATIVE DERMATOLOGY 73(1):8-14 HAYFLICK L CELL BIOLOGY OF AGING | 36 | 36 |
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