Nodes: 9502, Authors: 17414, Journals: 1567, Outer References: 209860, Words: 11576
Collection span: 1953 - 2005
View: Overview. Sorted by LCR.
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#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
1	314	569	5974 1987 MECHANISMS OF AGEING AND DEVELOPMENT 38(1):1-48 STANULISPRAEGER BM CELLULAR SENESCENCE REVISITED - A REVIEW	105	131
2	142	266	7069 1993 PHYSIOLOGICAL REVIEWS 73(3):617-638 CRISTOFALO VJ; PIGNOLO RJ REPLICATIVE SENESCENCE OF HUMAN FIBROBLAST-LIKE CELLS IN CULTURE	86	130
3	133	278	7893 1998 CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION 8(1):43-80 Cristofalo VJ; Volker C; Francis MK; Tresini M Age-dependent modifications of gene expression in human fibroblasts	21	38
4	128	273	8308 2000 BIOGERONTOLOGY 1(2):103-121 Duncan EL; Wadhwa R; Kaul SC Senescence and immortalization of human cells	5	8
5	124	338	9425 2004 MECHANISMS OF AGEING AND DEVELOPMENT 125(10-11):827-848 Cristofalo VJ; Lorenzini A; Allen RG; Torres C; Tresini M Replicative senescence: a critical review	0	0
6	93	611	4925 1983 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 58(3):343-422 MAKRIDES SC PROTEIN-SYNTHESIS AND DEGRADATION DURING AGING AND SENESCENCE	20	101
7	87	238	7136 1994 CRITICAL REVIEWS IN ONCOGENESIS 5(4):331-357 BRYAN TM; REDDEL RR SV40-INDUCED IMMORTALIZATION OF HUMAN-CELLS	46	116
8	84	162	5031 1983 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 83:183-220 MACIEIRACOELHO A CHANGES IN MEMBRANE-PROPERTIES ASSOCIATED WITH CELLULAR AGING	18	41
9	84	306	6264 1989 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 116:47-88 RATTAN SIS DNA DAMAGE AND REPAIR DURING CELLULAR AGING	23	45
10	81	209	1553 1971 BACTERIOLOGICAL REVIEWS 35(2):206-& STANBRIDGE E MYCOPLASMAS AND CELL CULTURES	81	163
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
11	78	208	7671 1997 BIOCHEMISTRY-MOSCOW 62(11):1263-1274 Duncan EL; Reddel RR Genetic changes associated with immortalization. A review	10	22
12	76	172	1922 1972 KLINISCHE WOCHENSCHRIFT 50(5):226-& SETHI KK; TESCHNER M MYCOPLASMA INTERACTIONS WITH CELL-CULTURES, UNCULTURED LIVING CELLS AND PROBLEMS POSED BY THEIR PRESENCE IN TISSUE-CULTURES	7	9
13	75	123	7541 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):111-123 Cristofalo VJ; Pignolo RJ Molecular markers of senescence in fibroblast-like cultures	17	32
14	74	364	3706 1978 MICROBIOLOGICAL REVIEWS 42(2):414-470 RAZIN S MYCOPLASMAS	38	279
15	69	123	4303 1980 MECHANISMS OF AGEING AND DEVELOPMENT 14(1-2):59-79 HAYFLICK L RECENT ADVANCES IN THE CELL BIOLOGY OF AGING	80	79
16	67	157	5289 1984 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 89:151-177 SMITH JR; LINCOLN DW AGING OF CELLS IN CULTURE	28	42
17	67	114	7637 1996 SCIENCE 273(5271):63-67 Smith JR; PereiraSmith OM Replicative senescence: Implications for in vivo aging and tumor suppression	130	279
18	66	185	7297 1995 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 1242(1):29-41 VOJTA PJ; BARRETT JC GENETIC-ANALYSIS OF CELLULAR SENESCENCE	33	57
19	64	193	7793 1997 MECHANISMS OF AGEING AND DEVELOPMENT 98(1):1-35 Rubin H Cell aging in vivo and in vitro	39	71
20	64	180	8927 2002 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 57(7):B257-B269 Marcotte R; Wang E Replicative senescence revisited	0	7
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
21	63	124	8471 2000 MOLECULAR AND CELLULAR GERONTOLOGY 908:111-125 Chen QM Replicative senescence and oxidant-induced premature senescence - Beyond the control of cell cycle checkpoints	10	27
22	62	224	7412 1995 MECHANISMS OF AGEING AND DEVELOPMENT 79(1):1-32 PAWELEC G MOLECULAR AND CELL BIOLOGICAL STUDIES OF AGING AND THEIR APPLICATION TO CONSIDERATIONS OF T-LYMPHOCYTE IMMUNOSENESCENCE	3	34
23	62	141	8886 2002 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 34(11):1415-1429 Toussaint O; Remacle J; Dierick JF; Pascal T; Frippiat C; et al. From the Hayflick mosaic to the mosaics of ageing. Role of stress-induced premature senescence in human ageing	4	8
24	59	192	2891 1976 ANNUAL REVIEW OF MICROBIOLOGY 30:169-187 STANBRIDGE EJ RE-EVALUATION OF ROLE OF MYCOPLASMAS IN HUMAN DISEASE	7	24
25	59	101	7131 1994 CELL STRUCTURE AND FUNCTION 19(1):1-10 WADHWA R; KAUL SC; MITSUI Y CELLULAR MORTALITY TO IMMORTALIZATION - MORTALIN	6	13
26	56	196	8217 1999 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 54(11):B502-B517 Wolf NS; Pendergrass WR The relationships of animal age and caloric intake to cellular replication in vivo and in vitro: A review	0	10
27	55	232	5820 1986 PEDIATRIC INFECTIOUS DISEASE JOURNAL 5(1):71-85 BROUGHTON RA INFECTIONS DUE TO MYCOPLASMA-PNEUMONIAE IN CHILDHOOD	1	61
28	55	448	9294 2004 CLINICAL MICROBIOLOGY REVIEWS 17(4):697-+ Waites KB; Talkington DF Mycoplasma pneumoniae and its role as a human pathogen	0	1
29	53	88	7866 1998 BIOESSAYS 20(12):977-984 Reddel RR A reassessment of the telomere hypothesis of senescence	16	44
30	52	252	1104 1969 ANNUAL REVIEW OF MICROBIOLOGY 23:317-& RAZIN S STRUCTURE AND FUNCTION IN MYCOPLASMA	32	79
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
31	51	81	7492 1996 BIOLOGICAL SIGNALS 5(3):130-138 Meyyappan M; Atadja PW; Riabowol KT Regulation of gene expression and transcription factor binding activity during cellular aging	10	20
32	50	160	3701 1978 MEDICAL CLINICS OF NORTH AMERICA 62(5):961-978 LEVINE DP; LERNER AM CLINICAL SPECTRUM OF MYCOPLASMA-PNEUMONIAE INFECTIONS	8	75
33	49	304	322 1965 BACTERIOLOGICAL REVIEWS 29(2):185-& HAYFLICK L; CHANOCK RM MYCOPLASMA SPECIES OF MAN	203	203
34	49	109	7780 1997 JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION 96(10):784-791 Chang ZF Regulatory mechanisms of replication growth limits in cellular senescence	1	3
35	48	152	6755 1992 CLINICAL BIOCHEMISTRY 25(2):61-75 KIRKLAND JL THE BIOCHEMISTRY OF MAMMALIAN SENESCENCE	10	19
36	48	287	7386 1995 JOURNAL OF ANATOMY 187:1-26 ASHCROFT GS; HORAN MA; FERGUSON MWJ THE EFFECTS OF AGING ON CUTANEOUS WOUND-HEALING IN MAMMALS	8	61
37	48	219	9192 2003 MOUNT SINAI JOURNAL OF MEDICINE 70(1):3-22 Troen BR The biology of aging	8	21
38	47	139	3781 1979 ANNEE BIOLOGIQUE 18(3-4):147-177 VANGANSEN P INVITRO-CELL AGING	1	2
39	46	135	3205 1977 AMERICAN JOURNAL OF PATHOLOGY 89(2):484-511 MARTIN GM CELLULAR AGING - CLONAL SENESCENCE .1.	74	93
40	46	136	4047 1979 TSITOLOGIYA 21(6):627-649 VANGANSEN P CELL AGING INVITRO	0	5
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
41	46	88	7132 1994 COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY 59:59-66 GOLETZ TJ; SMITH JR; PEREIRASMITH OM MOLECULAR-GENETIC APPROACHES TO THE STUDY OF CELLULAR SENESCENCE	2	3
42	46	84	8278 1999 ZEITSCHRIFT FUR GERONTOLOGIE UND GERIATRIE 32(2):69-75 Saretzki G; von Zglinicki T Replicative senescence as a model for aging: the role of oxidative stress and telomere shortening	0	1
43	45	158	5290 1984 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 92:93-132 KIRKWOOD TBL; HOLLIDAY R; ROSENBERGER RF STABILITY OF THE CELLULAR TRANSLATION PROCESS	15	42
44	45	63	6666 1991 MUTATION RESEARCH 256(2-6):169-175 YAMAMOTO K; YAMAMOTO M CHANGES IN THE CELL-SURFACE OF HUMAN-DIPLOID FIBROBLASTS DURING CELLULAR AGING	2	6
45	45	115	6967 1993 EXPERIMENTAL GERONTOLOGY 28(1):1-16 MACIEIRACOELHO A CONTRIBUTIONS MADE BY THE STUDIES OF CELLS-INVITRO FOR UNDERSTANDING OF THE MECHANISMS OF AGING	7	11
46	45	101	7769 1997 JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY 50(5):234-241 Kipling D; Faragher RGA Progeroid syndromes: probing the molecular basis of aging?	8	22
47	45	181	8268 1999 REVIEWS OF PHYSIOLOGY BIOCHEMISTRY AND PHARMACOLOGY, VOL 139 139:141-174 Hirsch-Kauffmann M; Schweiger M Aging and chromosomal instability	1	1
48	45	151	8906 2002 JOURNAL OF CELLULAR PHYSIOLOGY 192(1):23-33 Donehower LA Does p53 affect organismal aging?	6	24
49	45	106	9304 2004 CYTOGENETIC AND GENOME RESEARCH 105(2-4):455-463 Smith SK; Kipling D The role of replicative senescence in cancer and human ageing: utility (or otherwise) of murine models	0	0
50	44	227	1304 1970 ADVANCES IN HUMAN GENETICS (2):259-& MELLMAN WJ BIOCHEMICAL GENETIC VIEW OF HUMAN CELL-CULTURE	0	0
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
51	44	88	6518 1990 SCIENCE 249(4973):1129-1133 GOLDSTEIN S REPLICATIVE SENESCENCE - THE HUMAN FIBROBLAST COMES OF AGE	322	491
52	44	78	8576 2001 EUROPEAN JOURNAL OF BIOCHEMISTRY 268(10):2784-2791 Itahana K; Dimri G; Campisi J Regulation of cellular senescence by p53	21	55
53	44	119	9324 2004 EXPERIMENTAL CELL RESEARCH 300(1):1-10 de Magalhaes JP From cells to ageing: a review of models and mechanisms of cellular senescence and their impact on human ageing	0	0
54	43	205	312 1965 ANNUAL REVIEW OF MICROBIOLOGY 19:379-& EATON MD PLEUROPNEUMONIA-LIKE ORGANISMS AND RELATED FORMS	14	23
55	43	180	709 1967 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 143(A1):557-& BARILE MF MYCOPLASMA AND LEUKEMIA	17	26
56	43	178	2539 1974 PATHOLOGIA ET MICROBIOLOGIA 40(3-4):155-187 FREUNDT EA PRESENT STATUS OF MEDICAL IMPORTANCE OF MYCOPLASMAS	13	30
57	43	126	5876 1987 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 62(1):25-44 SEN S; TALUKDER G; SHARMA A AGE-RELATED ALTERATIONS IN HUMAN-CHROMOSOME COMPOSITION AND DNA CONTENT INVITRO DURING SENESCENCE	1	3
58	43	72	6662 1991 MUTATION RESEARCH 256(2-6):69-80 HAYFLICK L AGING UNDER GLASS	44	43
59	43	90	8045 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(16):9078-9081 Sedivy JM Can ends justify the means? Telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells	42	106
60	43	142	9212 2003 PATHOLOGIE BIOLOGIE 51(10):550-562 Macieira-Coelho A From Weismann's theory to present day gerontology 1889-2003	0	0
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
61	43	160	9448 2004 ONCOGENE 23(16):2919-2933 Shay JW; Roninson IB Hallmarks of senescence in carcinogenesis and cancer therapy	2	10
62	42	85	6730 1992 ARCHIVES FRANCAISES DE PEDIATRIE 49(10):927-935 PIUSSAN C GENETIC-BASIS OF EARLY AGING	0	0
63	42	121	7068 1993 PHYSIOLOGICAL REVIEWS 73(1):149-159 DICE JF CELLULAR AND MOLECULAR MECHANISMS OF AGING	19	69
64	42	120	7480 1996 ANTICANCER RESEARCH 16(5A):2901-2910 Derventzi A; Rattan SIS; Gonos ES Molecular links between cellular mortality and immortality (Review)	7	17
65	42	87	8384 2000 GERONTOLOGY 46(2):55-63 Macieira-Coelho A Ups and downs of aging studies in vitro: The crooked path of science	2	2
66	41	174	2234 1973 NEW ENGLAND JOURNAL OF MEDICINE 288(2):78-89 MCCORMAC.WM; BRAUN P; LEE YH; KLEIN JO; KASS EH GENITAL MYCOPLASMAS	0	156
67	41	117	4740 1982 HUMAN GENETICS 60(2):101-121 KIRKWOOD TBL; CREMER T CYTOGERONTOLOGY SINCE 1881 - A REAPPRAISAL OF AUGUST WEISMANN AND A REVIEW OF MODERN PROGRESS	25	74
68	41	106	8365 2000 EXPERIMENTAL GERONTOLOGY 35(8):927-945 Toussaint O; Medrano EE; von Zglinicki T Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes	39	73
69	41	125	8885 2002 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 34(11):1401-1414 Krtolica A; Campisi J Cancer and aging: a model for the cancer promoting effects of the aging stroma	3	13
70	41	307	9069 2003 CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY 45(3):277-304 Anisimov VN The relationship between aging and carcinogenesis: a critical appraisal	0	5
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
71	41	83	9099 2003 EXPERIMENTAL GERONTOLOGY 38(11-12):1259-1264 Von Zglinicki T Replicative senescence and the art of counting	3	6
72	40	148	6020 1988 ARCHIVES OF GERONTOLOGY AND GERIATRICS 7(1):31-74 VANGANSEN P; VANLERBERGHE N POTENTIAL AND LIMITATIONS OF CULTIVATED FIBROBLASTS IN THE STUDY OF SENESCENCE IN ANIMALS - A REVIEW ON THE MURINE SKIN FIBROBLASTS SYSTEM	2	8
73	40	59	6467 1990 JOURNALS OF GERONTOLOGY 45(2):B36-B41 HOLLIDAY R THE LIMITED PROLIFERATION OF CULTURED HUMAN-DIPLOID CELLS - REGULATION OR SENESCENCE	0	17
74	40	76	8905 2002 JOURNAL OF CELLULAR PHYSIOLOGY 190(3):332-344 Macera-Bloch L; Houghton J; Lenahan M; Jha KK; Ozer HL Termination of lifespan of SV40-transformed human fibroblasts in crisis is due to apoptosis	5	6
75	40	108	8955 2002 MOLECULES AND CELLS 13(3):351-361 Hahn WC Immortalization and transformation of human cells	0	2
76	40	99	8959 2002 NATURE BIOTECHNOLOGY 20(7):675-681 Rubin H The disparity between human cell senescence in vitro and lifelong replication in vivo	13	24
77	40	93	9097 2003 EXPERIMENTAL GERONTOLOGY 38(11-12):1231-1241 Hayflick L Living forever and dying in the attempt	2	2
78	39	145	1613 1971 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 7(1):26-& FOGH J; HOLMGREN NB; LUDOVICI PP REVIEW OF CELL CULTURE CONTAMINATIONS	21	55
79	39	107	7259 1994 PATHOLOGIE BIOLOGIE 42(4):313-321 TOUSSAINT O; REMACLE J REVIEW OF THE THEORIES OF CELLULAR AGING - FROM HAYFLICKS CONCEPT TO THE CONCEPT OF CRITICAL THRESHOLD OF ERROR ACCUMULATION - AN UPDATED REVIEW	1	2
80	39	77	7867 1998 BIOESSAYS 20(12):985-991 Faragher RGA; Kipling D How might replicative senescence contribute to human ageing?	21	47
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
81	39	61	7928 1998 EXPERIMENTAL GERONTOLOGY 33(5):393-419 Kitano H; Imai S The two-process model of cellular aging	3	5
82	39	95	9467 2004 REJUVENATION RESEARCH 7(2):126-133 de Magalhaes JP; Toussaint O Telomeres and telomerase: A modern fountain of youth?	0	0
83	38	74	4991 1983 EXPERIMENTAL GERONTOLOGY 18(3):223-240 RAES M; REMACLE J AGING OF HAMSTER-EMBRYO FIBROBLASTS AS THE RESULT OF BOTH DIFFERENTIATION AND STOCHASTIC MECHANISMS	21	27
84	38	71	7283 1995 AMERICAN JOURNAL OF PATHOLOGY 147(1):1-8 HENSLER PJ; PEREIRASMITH OM HUMAN REPLICATIVE SENESCENCE - A MOLECULAR STUDY	10	21
85	38	79	7706 1997 EUROPEAN JOURNAL OF CANCER 33(5):703-709 Campisi J The biology of replicative senescence	86	168
86	38	94	8201 1999 JOURNAL OF PATHOLOGY 187(1):100-111 Wynford-Thomas D Cellular senescence and cancer	22	68
87	38	77	8333 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(5):698-704 Ishikawa F Aging clock: the watchmaker's masterpiece	5	8
88	38	125	8912 2002 JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS 7(1):51-58 Yaar M; Eller MS; Gilchrest BA Fifty years of skin aging	0	3
89	37	72	4579 1981 MOLECULAR AND CELLULAR BIOCHEMISTRY 36(3):169-176 REFF M; SCHNEIDER EL CELL-CULTURE AGING	6	8
90	37	178	7619 1996 MUTATION RESEARCH-REVIEWS IN GENETIC TOXICOLOGY 366(1):45-63 Counter CM The roles of telomeres and telomerase in cell life span	9	45
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
91	37	94	7627 1996 ONCOLOGY RESEARCH 8(10-11):387-398 WynfordThomas D Telomeres, p53 and cellular senescence	5	15
92	37	80	7669 1997 BIOCHEMISTRY-MOSCOW 62(11):1180-1190 Hayflick L Mortality and immortality at the cellular level. A review	43	43
93	37	103	7922 1998 EXPERIMENTAL GERONTOLOGY 33(1-2):81-94 Garkavtsev I; Hull C; Riabowol K Molecular aspects of the relationship between cancer and aging: Tumor suppressor activity during cellular senescence	4	18
94	37	274	8947 2002 MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS 66(3):407-+ Cong YS; Wright WE; Shay JW Human telomerase and its regulation	6	49
95	37	105	8960 2002 NATURE BIOTECHNOLOGY 20(7):682-688 Wright WE; Shay JW Historical claims and current interpretations of replicative aging	28	71
96	37	112	9056 2003 CANCER RESEARCH 63(11):2705-2715 Roninson IB Tumor cell senescence in cancer treatment	3	16
97	37	64	9321 2004 EXPERIMENTAL CELL RESEARCH 298(2):549-559 Brooke S; Rowe J; del Arroyo AG; Bond J; Peters G Contribution of p16(INK4a) to replicative senescence of human fibroblasts	0	1
98	36	69	2718 1975 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 11(1):20-34 SCHNEIDER EL; STANBRIDGE EJ COMPARISON OF METHODS FOR DETECTION OF MYCOPLASMAL CONTAMINATION OF CELL-CULTURES - REVIEW	14	53
99	36	68	6545 1991 BIOESSAYS 13(11):601-606 RATTAN SIS; DERVENTZI A ALTERED CELLULAR RESPONSIVENESS DURING AGING	3	26
100	36	101	6765 1992 EUROPEAN JOURNAL OF CANCER 28A(8-9):1495-1500 STAMPS AC; GUSTERSON BA; OHARE MJ ARE TUMORS IMMORTAL	0	38
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
101	36	121	7274 1994 SURGICAL CLINICS OF NORTH AMERICA 74(1):1-21 CRISTOFALO VJ; GERHARD GS; PIGNOLO RJ MOLECULAR-BIOLOGY OF AGING	9	20
102	36	80	7501 1996 CANADIAN JOURNAL ON AGING-REVUE CANADIENNE DU VIEILLISSEMENT 15(2):315-329 Robetorye RS; Smith JR Regulation of the p21(Sdi1/Cip1/Waf1) DNA synthesis inhibitor in senescent human diploid fibroblasts	1	1
103	36	86	8069 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:8-19 Reddel RR Genes involved in the control of cellular proliferative potential	4	20
104	36	97	8680 2001 MATURITAS 38(1):25-37 Kipling D Telomeres, replicative senescence and human ageing	4	11
105	36	65	9107 2003 FEBS LETTERS 541(1-3):6-10 Yegorov YE; Zelenin AV Duration of senescent cell survival in vitro as a characteristic of organism longevity, an additional to the proliferative potential of fibroblasts	1	2
106	35	83	6612 1991 JOURNAL OF CELLULAR BIOCHEMISTRY 45(2):147-155 PEACOCKE M; CAMPISI J CELLULAR SENESCENCE - A REFLECTION OF NORMAL GROWTH-CONTROL, DIFFERENTIATION, OR AGING	37	61
107	35	67	6828 1992 JOURNAL OF CELLULAR PHYSIOLOGY 151(1):147-155 CHOI AMK; OLSEN DR; COOK KG; DEAMOND SF; UITTO J; et al. DIFFERENTIAL EXTRACELLULAR-MATRIX GENE-EXPRESSION BY FIBROBLASTS DURING THEIR PROLIFERATIVE LIFE-SPAN INVITRO AND AT SENESCENCE	11	22
108	35	64	7930 1998 EXPERIMENTAL GERONTOLOGY 33(6):555-570 Imai S; Kitano H Heterochromatin islands and their dynamic reorganization: A hypothesis for three distinctive features of cellular aging	4	10
109	35	59	8046 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(18):10614-10619 Cristofalo VJ; Allen RG; Pignolo RJ; Martin BG; Beck JC Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation	73	129
110	35	83	8325 2000 CARCINOGENESIS 21(3):477-484 Reddel RR The role of senescence and immortalization in carcinogenesis	19	52
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111	35	72	8941 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(8):927-936 Tominaga K; Olgun A; Smith JR; Pereira-Smith OM Genetics of cellular senescence	6	12
112	35	144	9101 2003 EXPERIMENTAL GERONTOLOGY 38(11-12):1285-1297 Srivastava VK; Busbee DL Replicative enzymes, DNA polymerase alpha (pol alpha), and in vitro ageing	0	1
113	34	92	561 1966 JOURNAL OF CELL SCIENCE 1(2):145-& MACPHERS.I MYCOPLASMAS IN TISSUE CULTURE	0	66
114	34	87	1740 1971 TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 105(3):257-& NIWAYAMA G; GRACE JT MYCOPLASMAS (PPLO) AND HUMAN NEOPLASMS	3	3
115	34	73	2020 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 225(DEC14):251-264 BARILE MF; HOPPS HE; GRABOWSK.MW; RIGGS DB; DELGIUDI.RA IDENTIFICATION AND SOURCES OF MYCOPLASMAS ISOLATED FROM CONTAMINATED CELL-CULTURES	27	62
116	34	84	2800 1975 MEDIZINISCHE KLINIK 70(1):1-9 BREDT W MYCOPLASMA INFECTIONS IN MAN	2	9
117	34	110	3001 1976 GERONTOLOGY 22(1-2):89-108 CHOE BK; ROSE NR INVITRO SENESCENCE OF MAMMALIAN-CELLS/PAN OF H	5	8
118	34	100	4286 1980 LYON MEDICAL 243(3):111-121 SEPETJAN M; CETRE JC MYCOPLASMAS AND HUMAN MYCOPLASMOSES	0	3
119	34	61	4679 1982 CELL AND TISSUE KINETICS 15(2):213-224 MACIEIRACOELHO A; TABOURY F A RE-EVALUATION OF THE CHANGES IN PROLIFERATION IN HUMAN-FIBROBLASTS DURING AGING INVITRO	39	52
120	34	63	8496 2000 PATHOLOGIE BIOLOGIE 48(3):301-307 Wynford-Thomas D Replicative senescence: mechanisms and implications for human cancer	1	4
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121	34	57	8585 2001 EXPERIMENTAL CELL RESEARCH 270(2):268-276 Sarraj S; Farb R; Martell RE Reconstitution of DNA synthetic capacity in senescent normal human fibroblasts by expressing cellular factors E2F and Mdm2	1	3
122	34	186	8887 2002 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 34(11):1430-1448 Trougakos IP; Gonos ES Clusterin/Apolipoprotein J in human aging and cancer	1	28
123	34	79	9060 2003 CANCER RESEARCH 63(21):7147-7157 Milyavsky M; Shats I; Erez N; Tang XH; Senderovich S; et al. Prolonged culture of telomerase-immortalized human fibroblasts leads to a premalignant phenotype	2	7
124	33	73	1663 1971 JOURNAL OF INFECTIOUS DISEASES 123(1):74-& DENNY FW MYCOPLASMA-PNEUMONIAE DISEASE - CLINICAL SPECTRUM, PATHOPHYSIOLOGY, EPIDEMIOLOGY, AND CONTROL	57	215
125	33	91	2638 1975 BIOSCIENCE 25(10):629-637 HAYFLICK L CELL BIOLOGY OF AGING	31	31
126	33	80	3808 1979 BIOLOGIE CELLULAIRE 34(2-3):255-269 VANGANSEN P; DEVOS L; OZORAN Y; ROXBURGH C PHENOTYPES OF EMBRYONIC MICE FIBROBLASTS AGING INVITRO (SEM AND TEM STUDY)	15	24
127	33	108	6442 1990 JOURNAL OF CELLULAR PHYSIOLOGY 144(2):313-325 WINKLES JA; OCONNOR ML; FRIESEL R ALTERED REGULATION OF PLATELET-DERIVED GROWTH-FACTOR A-CHAIN AND C-FOS GENE-EXPRESSION IN SENESCENT PROGERIA FIBROBLASTS	11	24
128	33	70	7416 1995 MECHANISMS OF AGEING AND DEVELOPMENT 81(2-3):139-157 FUKAMI J; ANNO K; UEDA K; TAKAHASHI T; IDE T ENHANCED EXPRESSION OF CYCLIN D-1 IN SENESCENT HUMAN FIBROBLASTS	8	19
129	33	65	8021 1998 MOLECULAR AND CELLULAR BIOLOGY 18(3):1611-1621 Gire V; Wynford-Thomas D Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies	33	70
130	33	181	8150 1999 FASEB JOURNAL 13(15):2091-2104 Liu JP Studies of the molecular mechanisms in the regulation of telomerase activity	6	89
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131	33	117	8956 2002 MUTAGENESIS 17(6):539-550 Newbold RF The significance of telomerase activation and cellular immortalization in human cancer	1	3
132	33	65	9153 2003 JOURNAL OF THEORETICAL BIOLOGY 225(2):153-170 Golubev A; Khrustalev S; Butov A An in silico investigation into the causes of telomere length heterogeneity and its implications for the Hayflick limit	0	0
133	32	69	7377 1995 INTERNATIONAL JOURNAL OF ONCOLOGY 7(1):69-74 WADHWA R; MITSUI Y; IDE T; KAUL SC THE ANTIPROLIFERATIVE ASPECTS OF MORTALIN (REVIEW)	2	6
134	32	110	7488 1996 BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 74(4):523-534 Wheaton K; Atadja P; Riabowol K Regulation of transcription factor activity during cellular aging	7	17
135	32	75	8593 2001 EXPERIMENTAL GERONTOLOGY 36(4-6):607-618 Campisi J From cells to organisms: can we learn about aging from cells in culture?	35	82
136	32	83	8943 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(12):1681-1694 Hwang ES Replicative senescence and senescence-like state induced in cancer-derived cells	3	6
137	32	111	9054 2003 CANCER LETTERS 194(2):163-172 Masutomi K; Hahn WC Telomerase and tumorigenesis	0	10
138	32	83	9257 2004 BIOGERONTOLOGY 5(1):1-10 Itahana K; Campisi J; Dimri GP Mechanisms of cellular senescence in human and mouse cells	1	2
139	31	86	1843 1972 EXPERIMENTAL CELL RESEARCH 74(1):99-& LEVINE EM MYCOPLASMA CONTAMINATION OF ANIMAL CELL-CULTURES - SIMPLE, RAPID DETECTION METHOD	54	186
140	31	117	6667 1991 MUTATION RESEARCH 256(2-6):177-189 POOT M OXIDANTS AND ANTIOXIDANTS IN PROLIFERATIVE SENESCENCE	9	33
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141	31	78	7004 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(12):8949-8957 PIGNOLO RJ; CRISTOFALO VJ; ROTENBERG MO SENESCENT WI-38 CELLS FAIL TO EXPRESS EPC-1, A GENE INDUCED IN YOUNG CELLS UPON ENTRY INTO THE G(0) STATE	30	72
142	31	66	7300 1995 BIOESSAYS 17(6):537-543 STEIN GH; DULIC V ORIGINS OF G(1) ARREST IN SENESCENT HUMAN FIBROBLASTS	28	72
143	31	45	8221 1999 M S-MEDECINE SCIENCES 15(10):1096-1104 Gire V; Wynford-Thomas D Senescence in human cells: an obstacle to tumour development?	0	2
144	31	161	8309 2000 BIOGERONTOLOGY 1(3):201-216 Srivastava VK; Miller S; Schroeder M; Crouch E; Busbee D Activity of DNA polymerase alpha in aging human fibroblasts	0	0
145	31	137	9039 2003 BIOCHEMISTRY-MOSCOW 68(1):2-33 Olovnikov AM The redusome hypothesis of aging and the control of biological time during individual development	1	1
146	30	69	1331 1970 ARCHIV FUR DIE GESAMTE VIRUSFORSCHUNG 30(2-3):113-& WITZLEB W ON CONTAMINATION OF TISSUE CULTURES WITH MYCOPLASMAS .1. ALTERATIONS OF CELLPHYSIOLOGY AND EFFECTS ON VIROLOGICAL DIAGNOSTICS (SURVEY OF LITERATURE)	4	4
147	30	166	3204 1977 AMERICAN JOURNAL OF PATHOLOGY 87(2):444-472 PITOT HC CARCINOGENESIS AND AGING - 2 RELATED PHENOMENA - REVIEW	6	33
148	30	156	4096 1980 BIOCHIMICA ET BIOPHYSICA ACTA 604(1):65-90 ROTTEM S MEMBRANE-LIPIDS OF MYCOPLASMAS	12	84
149	30	202	4474 1981 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 17(1):1-19 SACK GH HUMAN CELL-TRANSFORMATION BY SIMIAN VIRUS-40 - A REVIEW	47	139
150	30	163	7400 1995 JOURNAL OF MEDICAL MICROBIOLOGY 43(4):239-250 MARSHALL AJ; MILES RJ; RICHARDS L THE PHAGOCYTOSIS OF MYCOPLASMAS	0	12
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151	30	89	7898 1998 CURRENT SCIENCE 74(10):878-883 Parr E; Toyama T; Hull C; Meyyappan M; Bestilny L; et al. Molecular aspects of cellular senescence in human diploid fibroblasts	0	1
152	30	81	7960 1998 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 279(21):1732-1735 Fossel M Telomerase and the aging cell - Implications for human health	13	32
153	30	57	8110 1999 CANCER RESEARCH 59(20):5341-5348 Ma Y; Prigent SA; Born TL; Monell CR; Feramisco JR; et al. Microinjection of anti-p21 antibodies induces senescent Hs68 human fibroblasts to synthesize DNA but not to divide	2	7
154	30	45	8356 2000 EXPERIMENTAL GERONTOLOGY 35(1):7-13 Ran QT; Pereira-Smith OM Genetic approaches to the study of replicative senescence	7	11
155	30	132	8888 2002 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 34(11):1475-1490 Neumeister P; Albanese C; Balent B; Greally J; Pestell RG Senescence and epigenetic dysregulation in cancer	0	6
156	30	170	9146 2003 JOURNAL OF CLINICAL ONCOLOGY 21(10):2034-2043 Hahn WC Role of telomeres and telomerase in the pathogenesis of human cancer	1	8
157	29	253	718 1967 ANNUAL REVIEW OF MICROBIOLOGY 21:573-& GREEN H; TODARO GJ MAMMALIAN CELL AS DIFFERENTIATED MICROORGANISM	10	36
158	29	51	4836 1982 MECHANISMS OF AGEING AND DEVELOPMENT 20(1):75-92 PUVIONDUTILLEUL F; AZZARONE B; MACIEIRACOELHO A COMPARISON BETWEEN PROLIFERATIVE CHANGES AND NUCLEAR EVENTS DURING AGING OF HUMAN-FIBROBLASTS INVITRO	10	18
159	29	107	5271 1984 HUMAN IMMUNOLOGY 9(1):49-65 EFFROS RB; WALFORD RL T-CELL CULTURES AND THE HAYFLICK LIMIT	32	46
160	29	116	5273 1984 IN VITRO-JOURNAL OF THE TISSUE CULTURE ASSOCIATION 20(1):1-18 MCGARRITY GJ; VANAMAN V; SARAMA J CYTOGENETIC EFFECTS OF MYCOPLASMAL INFECTION OF CELL-CULTURES - A REVIEW	8	47
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161	29	58	5436 1985 ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY 190:353-372 PENDERGRASS W; SALK D; NORWOOD T CELL-FUSION STUDIES AND BIOCHEMICAL-ANALYSIS OF DNA-SYNTHESIS IN WERNER AND NON-WERNER CULTURED-CELLS	3	3
162	29	91	6664 1991 MUTATION RESEARCH 256(2-6):127-138 ELEFTHERIOU CS; TRAKAS NB; TZARTOS SJ CELLULAR AGING RELATED PROTEINS SECRETED BY HUMAN FIBROBLASTS	7	11
163	29	66	7435 1995 NUCLEIC ACIDS RESEARCH 23(16):3244-3251 LINSKENS MHK; FENG JL; ANDREWS WH; ENLOW BE; SAATI SM; et al. CATALOGING ALTERED GENE-EXPRESSION IN YOUNG AND SENESCENT CELLS USING ENHANCED DIFFERENTIAL DISPLAY	40	133
164	29	95	7520 1996 CRITICAL REVIEWS IN ONCOGENESIS 7(1-2):19-31 Namba M; Mihara K; Fushimi K Immortalization of human cells and las mechanisms	5	29
165	29	79	7547 1996 EXPERIMENTAL GERONTOLOGY 31(1-2):281-293 Howard BH Replicative senescence: Considerations relating to the stability of heterochromatin domains	13	27
166	29	104	7694 1997 CELLULAR AND MOLECULAR LIFE SCIENCES 53(7):568-575 Crompton NEA Telomeres, senescence and cellular radiation response	2	20
167	29	74	7704 1997 DRUG DISCOVERY TODAY 2(2):64-71 Faragher RGA; Shall S Gerontology and drug development: The challenge of the senescent cell	3	7
168	29	63	7800 1997 MOLECULAR AND CELLULAR BIOLOGY 17(3):1224-1235 Shibanuma M; Mochizuki E; Maniwa R; Mashimo J; Nishiya N; et al. Induction of senescence-like phenotypes by forced expression of hic-5, which encodes a novel LIM motif protein, in immortalized human fibroblasts	10	53
169	29	57	8335 2000 CURRENT OPINION IN CELL BIOLOGY 12(6):705-709 Lundberg AS; Hahn WG; Gupta P; Weinberg RA Genes involved in senescence and immortalization	23	70
170	29	104	8570 2001 DRUG RESISTANCE UPDATES 4(5):303-313 Roninson IB; Broude EV; Chang BD If not apoptosis, then what? - Treatment-induced senescence and mitotic catastrophe in tumor cells	7	61
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171	29	47	8580 2001 EXPERIMENTAL CELL RESEARCH 265(2):294-303 Chen QM; Prowse KR; Tu VC; Purdom S; Linskens MHK Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts	23	37
172	29	112	8707 2001 NATURE REVIEWS CANCER 1(3):203-213 Mathon NE; Lloyd AC Cell senescence and cancer	8	34
173	29	196	9104 2003 EXPERIMENTAL HEMATOLOGY 31(8):659-672 Van Zant G; Liang Y The role of stem cells in aging	2	9
174	29	78	9319 2004 EXPERIMENTAL CELL RESEARCH 295(2):525-538 Munro J; Barr NI; Ireland H; Morrison V; Parkinson EK Histone deacetylase inhibitors induce a senescence-like state in human cells by a p16-dependent mechanism that is independent of a mitotic clock	0	0
175	29	104	9496 2005 MECHANISMS OF AGEING AND DEVELOPMENT 126(1):51-58 Campisi J Aging, tumor suppression and cancer: high wire-act!	0	0
176	28	76	1810 1972 CALIFORNIA MEDICINE 116(5):1-& HARWICK HJ; KALMANSO.GM; GUZE LB HUMAN DISEASES ASSOCIATED WITH MYCOPLASMAS WITH AN APPENDIX ON SIMPLE CULTURE TECHNIQUES	4	6
177	28	69	4275 1980 JOURNAL OF THEORETICAL BIOLOGY 84(2):233-257 ADAM G POPULATION-DYNAMICAL MODEL OF CELL-DENSITY DEPENDENT GROWTH-REGULATION AND AGING OF FIBROBLASTS INVITRO	4	9
178	28	39	5384 1984 MECHANISMS OF AGEING AND DEVELOPMENT 28(2-3):177-185 HAYFLICK L INTRACELLULAR DETERMINANTS OF CELL AGING	32	32
179	28	367	5826 1986 PHYSIOLOGICAL REVIEWS 66(1):1-35 BETTGER WJ; MCKEEHAN WL MECHANISMS OF CELLULAR NUTRITION	1	29
180	28	36	6118 1988 MECHANISMS OF AGEING AND DEVELOPMENT 42(2):183-195 YAMAMOTO K; YAMAMOTO M; OOKA H CHANGES IN NEGATIVE SURFACE-CHARGE OF HUMAN-DIPLOID FIBROBLASTS, TIG-1, DURING INVITRO AGING	1	1
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181	28	103	6663 1991 MUTATION RESEARCH 256(2-6):115-125 RATTAN SIS PROTEIN-SYNTHESIS AND THE COMPONENTS OF PROTEIN SYNTHETIC MACHINERY DURING CELLULAR AGING	1	28
182	28	65	7608 1996 MOLECULAR AND CELLULAR BIOLOGY 16(9):5127-5138 Gonos ES; Burns JS; Mazars GR; Kobrna A; Riley TEW; et al. Rat embryo fibroblasts immortalized with simian virus 40 large T antigen undergo senescence upon its inactivation	15	32
183	28	81	7709 1997 EUROPEAN JOURNAL OF CANCER 33(5):727-734 Parkinson EK; Newbold RF; Keith WN The genetic basis of human keratinocyte immortalisation in squamous cell carcinoma development: The role of telomerase reactivation	5	26
184	28	80	8360 2000 EXPERIMENTAL GERONTOLOGY 35(5):553-571 Yeo EJ; Hwang YC; Kang CM; Kim IH; Kim DI; et al. Senescence-like changes induced by hydroxyurea in human diploid fibroblasts	3	11
185	28	63	9431 2004 MOLECULAR AND CELLULAR BIOLOGY 24(12):5459-5474 Satyanarayana A; Greenberg RA; Schaetzlein S; Buer J; Masutomi K; et al. Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling	0	3
186	28	65	9498 2005 MECHANISMS OF AGEING AND DEVELOPMENT 126(1):111-117 von Zglinicki T; Saretzki G; Ladhoff J; di Fagagna FD; Jackson SP Human cell senescence as a DNA damage response	0	0
187	27	230	1536 1971 ANNUAL REVIEW OF PHYTOPATHOLOGY 9:119-& DAVIS RE; WHITCOMB RF MYCOPLASMAS, RICKETTSIAE, AND CHLAMYDIAE - POSSIBLE RELATION TO YELLOWS DISEASES AND OTHER DISORDERS OF PLANTS AND INSECTS	11	64
188	27	184	1786 1972 BACTERIOLOGICAL REVIEWS 36(3):263-& MANILOFF J; MOROWITZ HJ CELL BIOLOGY OF MYCOPLASMAS	13	101
189	27	391	2572 1974 PROGRESS IN MEDICAL VIROLOGY 17:221-289 HERRMANN EC NEW CONCEPTS AND DEVELOPMENTS IN APPLIED DIAGNOSTIC VIROLOGY	1	8
190	27	100	4183 1980 GERONTOLOGY 26(3):138-154 WHATLEY SA; HILL BT INVITRO AGING AND NUCLEAR TEMPLATE FUNCTION	3	5
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191	27	57	4561 1981 MECHANISMS OF AGEING AND DEVELOPMENT 16(3):241-253 ROHME D AGING AND THE FUSION SENSITIVITY POTENTIAL OF HUMAN-CELLS IN CULTURE - RELATION TO TISSUE ORIGIN, DONOR AGE, AND INVITRO CULTURE LEVEL AND CONDITION	2	3
192	27	101	4671 1982 BULLETIN ON THE RHEUMATIC DISEASES 32(2):13-19 WALLACE DJ; BLUESTONE R; KLINENBERG JR THE BIOLOGY OF AGING AND THE IMMUNE-SYSTEM	1	2
193	27	97	4723 1982 EXPERIMENTAL GERONTOLOGY 17(4):305-317 LAUGHREA M ON THE ERROR THEORIES OF AGING - A REVIEW OF THE EXPERIMENTAL-DATA	7	20
194	27	361	5032 1983 INTERNATIONAL REVIEW OF EXPERIMENTAL PATHOLOGY 24:135-202 COLLINS VP CULTURED HUMAN GLIAL AND GLIOMA-CELLS	4	57
195	27	70	5181 1984 AGE 7(3):75-88 TOLLEFSBOL TO; COHEN HJ WERNERS SYNDROME - AN UNDERDIAGNOSED DISORDER RESEMBLING PREMATURE AGING	14	43
196	27	210	6368 1990 BIOLOGICAL REVIEWS OF THE CAMBRIDGE PHILOSOPHICAL SOCIETY 65(3):375-398 MEDVEDEV ZA AN ATTEMPT AT A RATIONAL CLASSIFICATION OF THEORIES OF AGING	24	99
197	27	51	6715 1992 AMERICAN JOURNAL OF CLINICAL NUTRITION 55(6):S1215-S1221 SMITH JR; NING Y; PEREIRASMITH OM WHY ARE TRANSFORMED-CELLS IMMORTAL - IS THE PROCESS REVERSIBLE	0	14
198	27	38	6720 1992 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 663:187-194 CRISTOFALO VJ; PIGNOLO RJ; ROTENBERG MO MOLECULAR-CHANGES WITH INVITRO CELLULAR SENESCENCE	9	14
199	27	81	7829 1997 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 214(2):99-106 Chiu CP; Harley CB Replicative senescence and cell immortality: The role of telomeres and telomerase	21	89
200	27	66	7966 1998 JOURNAL OF CELLULAR PHYSIOLOGY 174(1):90-98 Mu XC; StaianoCoico L; Higgins PJ Increased transcription and modified growth state-dependent expression of the plasminogen activator inhibitor type-1 gene characterize the senescent phenotype in human diploid fibroblasts	2	12
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201	27	62	8058 1998 SCIENCE 279(5349):349-352 Bodnar AG; Ouellette M; Frolkis M; Holt SE; Chiu CP; et al. Extension of life-span by introduction of telomerase into normal human cells	426	1466
202	27	163	8077 1999 AGE 22(2):45-57 Hadshiew IM; Eller MS; Gilchrest BA Age-associated decreases in human DNA repair capacity: Implications for the skin	0	2
203	27	94	8111 1999 CARCINOGENESIS 20(6):921-926 Huschtscha LI; Reddel RR p16(INK4a) and the control of cellular proliferative life span - Commentary	11	49
204	27	578	8375 2000 FREE RADICAL BIOLOGY AND MEDICINE 28(3):463-499 Allen RG; Tresini M Oxidative stress and gene regulation	5	216
205	27	59	8733 2001 RADIATION RESEARCH 155(1):188-193 Shay JW; Wright WE Telomeres and telomerase: Implications for cancer and aging	9	29
206	27	157	8965 2002 NATURE REVIEWS CANCER 2(5):331-341 Hahn WC; Weinberg RA Modelling the molecular circuitry of cancer	8	132
207	27	74	9082 2003 EXPERIMENTAL CELL RESEARCH 283(1):22-35 Stephens P; Cook H; Hilton J; Jones CJ; Haughton MF; et al. An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype	2	4
208	27	212	9289 2004 CELLULAR AND MOLECULAR LIFE SCIENCES 61(6):641-656 Mathieu N; Pirzio L; Freulet-Marriere MA; Desmaze C; Sabatier L Telomeres and chromosomal instability	0	4
209	27	95	9325 2004 EXPERIMENTAL CELL RESEARCH 301(2):189-200 Li GZ; Eller MS; Hanna K; Gilchrest BA Signaling pathway requirements for induction of senescence by telomere homolog oligonucleotides	0	0
210	27	65	9346 2004 GENES & DEVELOPMENT 18(24):3028-3040 Zhang H; Cohen SN Smurf2 up-regulation activates telomere-dependent senescence	0	0
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211	27	112	9393 2004 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 36(2):175-183 Minamino T; Miyauchi H; Yoshida T; Tateno K; Kunieda T; et al. Vascular cell senescence and vascular aging	0	3
212	26	63	842 1967 NOUVELLE REVUE FRANCAISE D HEMATOLOGIE 7(2):215-& LECLERC JC; SILVESTR.D MYCOPLASMES ET HEMOPATHIES HUMAINES	0	3
213	26	54	5374 1984 MECHANISMS OF AGEING AND DEVELOPMENT 26(2-3):341-356 OKADA AA; DICE JF ALTERED DEGRADATION OF INTRACELLULAR PROTEINS IN AGING HUMAN-FIBROBLASTS	13	26
214	26	38	5953 1987 JOURNAL OF CELLULAR PHYSIOLOGY 132(1):125-130 ANGELLO JC; PENDERGRASS WR; NORWOOD TH; PROTHERO J PROLIFERATIVE POTENTIAL OF HUMAN-FIBROBLASTS - AN INVERSE DEPENDENCE ON CELL-SIZE	15	29
215	26	56	6766 1992 EXPERIMENTAL CELL RESEARCH 199(2):355-362 WISTROM C; VILLEPONTEAU B CLONING AND EXPRESSION OF SAG - A NOVEL MARKER OF CELLULAR SENESCENCE	31	37
216	26	389	7075 1993 PROGRESS IN RETINAL RESEARCH 12:101-131 ELDRED GE BIOCHEMICAL AGING IN THE RETINA AND RPE	1	7
217	26	58	7351 1995 EXPERIMENTAL CELL RESEARCH 220(1):178-185 DIPAOLO BR; PIGNOLO RJ; CRISTOFALO VJ IDENTIFICATION OF PROTEINS DIFFERENTIALLY EXPRESSED IN QUIESCENT AND PROLIFERATIVELY SENESCENT FIBROBLAST-CULTURES	7	21
218	26	76	7375 1995 INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 27(9):937-945 MAYS PK; MCANULTY RJ; CAMPA JS; LAURENT GJ AGE-RELATED ALTERATIONS IN COLLAGEN AND TOTAL PROTEIN-METABOLISM DETERMINED IN CULTURED RAT DERMAL FIBROBLASTS - AGE-RELATED TRENDS PARALLEL THOSE OBSERVED IN RAT SKIN IN-VIVO	2	4
219	26	49	7444 1995 ONCOGENE 11(6):1125-1132 TAHARA H; KAMADA K; SATO E; TSUYAMA N; KIM JK; et al. INCREASE IN EXPRESSION LEVELS OF INTERFERON-INDUCIBLE GENES IN SENESCENT HUMAN-DIPLOID FIBROBLASTS AND IN SV40-TRANSFORMED HUMAN FIBROBLASTS WITH EXTENDED LIFE-SPAN	7	16
220	26	56	7532 1996 EXPERIMENTAL CELL RESEARCH 228(1):138-145 Wang SM; Phillips PD; Sierra F; Cristofalo VJ Altered expression of the twist gene in young versus senescent human diploid fibroblasts	1	5
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221	26	91	7609 1996 MOLECULAR AND CELLULAR BIOLOGY 16(9):5210-5218 Ogryzko VV; Hirai TH; Russanova VR; Barbie DA; Howard BH Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent	44	92
222	26	49	7920 1998 EXPERIMENTAL CELL RESEARCH 245(1):1-7 Jha KK; Banga S; Palejwala V; Ozer HL SV40-mediated immortalization	11	36
223	26	65	8153 1999 FREE RADICAL BIOLOGY AND MEDICINE 27(7-8):729-737 Ricciarelli R; Maroni P; Ozer N; Zingg JM; Azzi A Age-dependent increase of collagenase expression can be reduced by alpha-tocopherol via protein kinase C inhibition	0	37
224	26	61	8374 2000 FREE RADICAL BIOLOGY AND MEDICINE 28(3):361-373 Dumont P; Burton M; Chen QM; Gonos ES; Frippiat C; et al. Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast	35	70
225	26	161	8562 2001 CRITICAL REVIEWS IN ORAL BIOLOGY & MEDICINE 12(1):38-54 Kang MK; Park NH Conversion of normal to malignant phenotype: Telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes	0	10
226	26	96	8590 2001 EXPERIMENTAL GERONTOLOGY 36(2):193-203 Hamerman D; Zeleznik J Translating basic aging research into geriatric health care	0	3
227	26	69	8656 2001 JOURNAL OF CELLULAR PHYSIOLOGY 187(2):226-235 Wheaton K; Sampsel K; Boisvert FM; Davy A; Robbins S; et al. Loss of functional caveolae during senescence of human fibroblasts	3	9
228	26	47	8728 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(2):646-651 O'Hare MJ; Bond J; Clarke C; Takeuchi Y; Atherton AJ; et al. Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells	0	46
229	26	59	8769 2002 ARCHIVES OF GERONTOLOGY AND GERIATRICS 34(3):275-286 Rubin H Promise and problems in relating cellular senescence in vitro to aging in vivo	1	2
230	26	117	8785 2002 BIOGERONTOLOGY 3(4):195-206 Bree RT; Stenson-Cox C; Grealy M; Byrnes L; Gorman AM; et al. Cellular longevity: role of apoptosis and replicative senescence	4	8
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231	26	44	8891 2002 INTERNATIONAL JOURNAL OF ONCOLOGY 21(4):851-856 Kumata M; Shimizu M; Oshimura M; Uchida M; Tsutsui T Induction of cellular senescence in a telomerase negative human immortal fibroblast cell line, LCS-AF.1-3, by human chromosome 6	0	3
232	26	92	8940 2002 MECHANISMS OF AGEING AND DEVELOPMENT 123(7):801-810 Jenkins G Molecular mechanisms of skin ageing	0	10
233	26	49	9001 2002 TRENDS IN BIOCHEMICAL SCIENCES 27(7):339-344 von Zglinicki T Oxidative stress shortens telomeres	25	71
234	26	133	9442 2004 NEUROCHEMICAL RESEARCH 29(3):617-628 Esposito F; Ammendola R; Faraonio R; Russo T; Cimino F Redox control of signal transduction, gene expression and cellular senescence	0	4
235	25	73	2796 1975 MECHANISMS OF AGEING AND DEVELOPMENT 4(5-6):339-348 GOOD PI AGING IN MAMMALIAN-CELL POPULATIONS - REVIEW	12	15
236	25	45	3957 1979 JOURNAL OF INVESTIGATIVE DERMATOLOGY 73(1):8-14 HAYFLICK L CELL BIOLOGY OF AGING	36	36
237	25	70	4005 1979 MEDICAL HYPOTHESES 5(1):53-66 EVANS CH AGING OF ORGANISMS AND THEIR CELLS	9	13
238	25	55	4239 1980 JOURNAL OF CELLULAR PHYSIOLOGY 103(2):209-216 GUPTA RS SENESCENCE OF CULTURED HUMAN-DIPLOID FIBROBLASTS - ARE MUTATIONS RESPONSIBLE	16	31
239	25	43	4545 1981 JOURNAL OF THEORETICAL BIOLOGY 93(3):627-642 HOLLIDAY R; KIRKWOOD TBL PREDICTIONS OF THE SOMATIC MUTATION AND MORTALIZATION THEORIES OF CELLULAR AGING ARE CONTRARY TO EXPERIMENTAL-OBSERVATIONS	22	33
240	25	65	4594 1981 PLASTIC AND RECONSTRUCTIVE SURGERY 67(4):536-550 HAYFLICK L THE BIOLOGY OF HUMAN AGING	12	12
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
241	25	42	4827 1982 MECHANISMS OF AGEING AND DEVELOPMENT 18(1):75-87 NETTE EG; SIT HL; KING DW REACTIVATION OF DNA-SYNTHESIS IN AGING DIPLOID HUMAN-SKIN FIBROBLASTS BY FUSION WITH MOUSE L-KARYOPLASTS, CYTOPLASTS AND WHOLE L-CELLS	8	10
242	25	130	4834 1982 MECHANISMS OF AGEING AND DEVELOPMENT 19(3):217-244 WALTON J THE ROLE OF LIMITED CELL REPLICATIVE CAPACITY IN PATHOLOGICAL AGE CHANGE - A REVIEW	10	20
243	25	104	6249 1989 GENOME 31(1):406-412 REIS RJS MODEL SYSTEMS FOR AGING RESEARCH - SYNCRETIC CONCEPTS AND DIVERSITY OF MECHANISMS	0	3
244	25	43	6305 1989 MECHANISMS OF AGEING AND DEVELOPMENT 47(3):187-197 RIGNEY DR; WEI JY NOTE ON THE DISPERSION OF GENERATIONS AMONG CELLS IN SENESCING DIPLOID FIBROBLAST POPULATIONS	0	0
245	25	83	6567 1991 EXPERIMENTAL CELL RESEARCH 192(1):128-136 DENHARDT DT; EDWARDS DR; MCLEOD M; NORTON G; PARFETT CLJ; et al. SPONTANEOUS IMMORTALIZATION OF MOUSE EMBRYO CELLS - STRAIN DIFFERENCES AND CHANGES IN GENE-EXPRESSION WITH PARTICULAR REFERENCE TO RETROVIRAL GAG-POL GENES	2	10
246	25	53	6718 1992 ANNALS OF MEDICINE 24(5):313-318 KOLI K; KESKIOJA J CELLULAR SENESCENCE	2	13
247	25	39	7335 1995 EXPERIMENTAL CELL RESEARCH 216(1):101-106 WADHWA R; PEREIRASMITH OM; REDDEL RR; SUGIMOTO Y; MITSUI Y; et al. CORRELATION BETWEEN COMPLEMENTATION GROUP FOR IMMORTALITY AND THE CELLULAR-DISTRIBUTION OF MORTALIN	15	37
248	25	44	7718 1997 EXPERIMENTAL CELL RESEARCH 235(2):345-353 Nakabayashi K; Ogata T; Fujii M; Tahara H; Ide T; et al. Decrease in amplified telomeric sequences and induction of senescence markers by introduction of human chromosome 7 or its segments in SUSM-1	15	34
249	25	63	7765 1997 JOURNAL OF CELLULAR PHYSIOLOGY 171(3):325-335 Pardinas J; Pang Z; Houghton J; Palejwala V; Donnelly RJ; et al. Differential gene expression in SV40-mediated immortalization of human fibroblasts	6	8
250	25	35	8371 2000 FEBS LETTERS 474(2-3):159-164 Kaul SC; Reddel RR; Sugihara T; Mitsui Y; Wadhwa R Inactivation of p53 and life span extension of human diploid fibroblasts by mot-2	3	22
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
251	25	59	8511 2000 SEMINARS IN CANCER BIOLOGY 10(6):399-406 Stewart SA; Weinberg RA Telomerase and human tumorigenesis	4	30
252	25	74	8547 2001 CANADIAN JOURNAL OF MICROBIOLOGY 47(8):691-697 Cimolai N Do mycoplasmas cause human cancer?	0	1
253	25	63	8564 2001 CURRENT OPINION IN CELL BIOLOGY 13(6):748-753 Serrano M; Blasco MA Putting the stress on senescence	30	59
254	25	168	8629 2001 HUMAN MOLECULAR GENETICS 10(7):677-685 Shay JW; Zou Y; Hiyama E; Wright WE Telomerase and cancer	2	60
255	25	89	8666 2001 JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 49(8):1105-1109 Ahmed A; Tollefsbol T Telomeres and telomerase: Basic science implications for aging	4	9
256	25	111	8756 2002 AGEING RESEARCH REVIEWS 1(3):443-463 Srivastava VK; Busbee DL Replicative enzymes and ageing: importance of DNA polymerase alpha function to the events of cellular ageing	0	0
257	25	54	8841 2002 EXPERIMENTAL CELL RESEARCH 274(2):275-287 Balin AK; Fisher AJ; Anzelone M; Leong I; Allen RG Effects of establishing cell cultures and cell culture conditions on the proliferative life span of human fibroblasts isolated from different tissues and donors of different ages	7	11
258	25	52	9221 2003 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100(6):3251-3256 Zhang H; Pan KH; Cohen SN Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci	7	16
259	24	72	680 1967 AMERICAN JOURNAL OF THE MEDICAL SCIENCES 253(6):639-& JAO RL; FINLAND M SUSCEPTIBILITY OF MYCOPLASMA PNEUMONIAE TO 21 ANTIBIOTICS IN VITRO	20	66
260	24	115	1045 1968 PATHOLOGIE BIOLOGIE 16(11-1):677-& BOUE A; BOUE JG EFFECT OF VIRUS INFECTIONS ON HUMAN CHROMOSOMES	0	3
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
261	24	112	2609 1975 AMERICAN JOURNAL OF MEDICINE 58(2):229-242 MURRAY HW; MASUR H; SENTERFIT LB; ROBERTS RB PROTEAN MANIFESTATIONS OF MYCOPLASMA PNEUMONIAE INFECTION IN ADULTS	25	239
262	24	62	3285 1977 EXPERIMENTAL CELL RESEARCH 110(1):63-73 MILLER RC; NICHOLS WW; POTTASH J; ARONSON MM INVITRO AGING - CYTOGENETIC COMPARISON OF DIPLOID HUMAN FIBROBLAST AND EPITHELIOID CELL LINES	27	40
263	24	108	4133 1980 CRC CRITICAL REVIEWS IN DIAGNOSTIC IMAGING 12(4):385-415 JENSEN PS; HALBER MD; PUTMAN CE MYCOPLASMA-PNEUMONIA	1	3
264	24	229	4269 1980 JOURNAL OF SCIENTIFIC & INDUSTRIAL RESEARCH 39(7):381-401 KANUNGO MS BIOCHEMICAL AND MOLECULAR ASPECTS OF AGING	1	1
265	24	136	4566 1981 MECHANISMS OF AGEING AND DEVELOPMENT 17(1):53-94 WITTEN M MODELING CELLULAR-SYSTEMS AND AGING PROCESSES .1. MATHEMATICS OF CELL SYSTEM MODELS - A REVIEW	5	19
266	24	53	5429 1984 ZEITSCHRIFT FUR GERONTOLOGIE 17(3):141-149 SCHACHTSCHABEL DO; SLUKE G AGE-DEPENDENT INFLUENCE OF CORTISOL ON GLYCOSAMINOGLYCAN SYNTHESIS AND GROWTH OF DIPLOID, HUMAN-FIBROBLASTS (WI-38) IN CULTURE	0	4
267	24	212	5466 1985 BIOCHIMICA ET BIOPHYSICA ACTA 823(3):161-194 CHANG SE INVITRO TRANSFORMATION OF HUMAN EPITHELIAL-CELLS	0	0
268	24	105	7353 1995 EXPERIMENTAL GERONTOLOGY 30(1):1-22 TOUSSAINT O; MICHIELS C; RAES M; REMACLE J CELLULAR AGING AND THE IMPORTANCE OF ENERGETIC FACTORS	11	23
269	24	96	7804 1997 MOLECULAR BIOLOGY 31(1):10-17 Egorov EE Telomerase, aging, and cancer	0	0
270	24	47	7993 1998 JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 53(6):B438-B442 Saretzki G; Feng JL; von Zglinicki T; Villeponteau B Similar gene expression pattern in senescent and hyperoxic-treated fibroblasts	0	33
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
271	24	58	8070 1998 TOWARDS PROLONGATION OF THE HEALTHY LIFE SPAN 854:318-327 Von Zglinicki T Telomeres: Influencing the rate of aging	10	24
272	24	45	8104 1999 BRITISH JOURNAL OF CANCER 80:42-45 Black DM Characterization of a multi-tissue tumour suppressor and senescence gene	0	4
273	24	55	8211 1999 JOURNAL OF THEORETICAL BIOLOGY 197(4):425-438 Rubelj I; Vondracek Z Stochastic mechanism of cellular aging - Abrupt telomere shortening as a model for stochastic nature of cellular aging	19	30
274	24	246	8331 2000 CELLULAR AND MOLECULAR LIFE SCIENCES 57(3):464-486 Krupp G; Klapper W; Parwaresch R Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation	0	12
275	24	49	8712 2001 ONCOGENE 20(27):3541-3552 Munro J; Steeghs K; Morrison V; Ireland H; Parkinson EK Human fibroblast replicative senescence can occur in the absence of extensive cell division and short telomeres	9	19
276	24	584	8757 2002 AGEING RESEARCH REVIEWS 1(3):481-536 Heininger K Aging is a deprivation syndrome driven by a germ-soma conflict	0	3
277	24	59	8768 2002 ARCHIVES OF DERMATOLOGY 138(11):1429-1432 Yaar M Mechanisms of aging	0	1
278	24	52	8811 2002 CANCER RESEARCH 62(17):5076-5082 Haq R; Brenton JD; Takahashi M; Finan D; Rottapel R; et al. Constitutive p38HOG mitogen-activated protein kinase activation induces permanent cell cycle arrest and senescence	5	13
279	24	51	8851 2002 EXPERIMENTAL GERONTOLOGY 37(7):851-857 Holliday R Twenty years of ageing research at the Mill Hill laboratories	0	1
280	24	47	8974 2002 ONCOGENE 21(4):627-630 Stewart SA; Weinberg RA Senescence: does it all happen at the ends?	4	27
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
281	24	62	8998 2002 TOXICOLOGY AND INDUSTRIAL HEALTH 18(8):365-376 Pompei F; Wilson R A quantitative model of cellular senescence influence on cancer and longevity	0	0
282	24	79	9016 2003 AGING CELL 2(3):145-150 Collins CJ; Sedivy JM Involvement of the INK4a/Arf gene locus in senescence	1	3
283	24	56	9381 2004 JOURNAL OF CLINICAL INVESTIGATION 113(1):8-13 Ben-Porath I; Weinberg RA When cells get stressed: an integrative view of cellular senescence	4	13
284	23	68	448 1965 TEXAS REPORTS ON BIOLOGY AND MEDICINE 23:285-& HAYFLICK L TISSUE CULTURES AND MYCOPLASMAS	925	923
285	23	49	1332 1970 ARCHIV FUR DIE GESAMTE VIRUSFORSCHUNG 30(2-3):121-& WITZLEB W; BLUMOHR T; DZIAMBOR H; SCHWEIZE.H ON CONTAMINATION OF TISSUE CULTURES WITH MYCOPLASMAS .2. DETECTION AND SEROLOGICAL IDENTIFICATION OF MYCOPLASMAS	6	7
286	23	47	1368 1970 DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 95(5):234-& BREDT W SEROLOGICAL DIAGNOSIS IN HUMAN MYCOPLASMA INFECTION	2	2
287	23	128	1808 1972 BULLETIN DE L INSTITUT PASTEUR 70(1):51-& ZAVADOVA M GENUS MYCOPLASMA	0	3
288	23	79	2433 1974 INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY 24(2):160-171 SHEPARD MC; LUNCEFOR.CD; FORD DK; PURCELL RH; TAYLORRO.D; et al. UREAPLASMA-UREALYTICUM GEN-NOV, SP-NOV - PROPOSED NOMENCLATURE FOR HUMAN-T (T-STRAIN) MYCOPLASMAS	56	170
289	23	60	2885 1976 ANNALI SCLAVO 18(2):249-259 FADDA G SIGNIFICANCE OF MYCOPLASMA SPECIES IN RESPIRATORY-TRACT	0	0
290	23	79	3185 1976 WESTERN JOURNAL OF MEDICINE 125(1):47-55 CHERRY JD; WELLIVER RC MYCOPLASMA PNEUMONIAE INFECTIONS OF ADULTS AND CHILDREN	3	11
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
291	23	39	3769 1979 ACTA PATHOLOGICA ET MICROBIOLOGICA SCANDINAVICA SECTION A-PATHOLOGY 87(5):393-399 BLOMQUIST E; ARRO E; BRUNK U; WESTERMARK B GROWTH-STIMULATION OF AGED CELLS IN CULTURE	2	5
292	23	41	3880 1979 GERONTOLOGY 25(3):136-144 MORROW J; GARNER C EVALUATION OF SOME THEORIES OF THE MECHANISM OF AGING	11	15
293	23	43	4553 1981 MECHANISMS OF AGEING AND DEVELOPMENT 15(1):51-63 STEVENSON AFG; CREMER T SENESCENCE INVITRO AND IONIZING-RADIATIONS - THE HUMAN-DIPLOID FIBROBLAST MODEL	2	7
294	23	49	4960 1983 COMPUTERS & MATHEMATICS WITH APPLICATIONS 9(3):447-457 WITTEN M ON STOCHASTICITY IN THE VON-FOERSTER HYPERBOLIC PARTIAL-DIFFERENTIAL EQUATION SYSTEM - FURTHER APPLICATIONS TO THE MODELING OF AN ASYNCHRONOUSLY DIVIDING CELLULAR-SYSTEM	0	2
295	23	115	5391 1984 MOLECULAR AND CELLULAR BIOCHEMISTRY 64(1):15-30 GOLDSTEIN S; REIS RJS GENETIC MODIFICATIONS DURING CELLULAR AGING	7	20
296	23	149	5622 1985 MOLECULAR ASPECTS OF MEDICINE 8(1):1-& ROY AK; CHATTERJEE B MOLECULAR ASPECTS OF AGING	1	18
297	23	87	5935 1987 ISRAEL JOURNAL OF MEDICAL SCIENCES 23(5):318-325 RAZIN S APPEALING ATTRIBUTES OF MYCOPLASMAS IN CELL BIOLOGY RESEARCH	0	1
298	23	44	6085 1988 INFECTION AND IMMUNITY 56(3):570-576 CHEN YY; KRAUSE DC PARASITISM OF HAMSTER TRACHEA EPITHELIAL-CELLS BY MYCOPLASMA-PNEUMONIAE	3	5
299	23	173	6944 1993 CRITICAL REVIEWS IN ONCOGENESIS 4(3):313-335 RHIM JS NEOPLASTIC TRANSFORMATION OF HUMAN-CELLS INVITRO	7	25
300	23	82	7047 1993 MEDICAL HYPOTHESES 41(4):384-389 CHIGIRA M; WATANABE H IS SENESCENCE OF DIPLOID-CELLS AN AD HOC MECHANISM SUPPRESSING REPLICON OR NOT	0	3

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