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Nodes: 2647,
Authors: 5321,
Journals: 428,
Outer References: 16458,
Words: 3536
Collection span: 1967 - 2005
View: Overview. Sorted by GCS.
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
|---|---|---|---|---|---|
| 1 | 11 | 40 | 846 1991 CELL 65(5):905-914 VERKERK AJMH; PIERETTI M; SUTCLIFFE JS; FU YH; KUHL DPA; et al. IDENTIFICATION OF A GENE (FMR-1) CONTAINING A CGG REPEAT COINCIDENT WITH A BREAKPOINT CLUSTER REGION EXHIBITING LENGTH VARIATION IN FRAGILE-X SYNDROME | 576 | 1282 |
| 2 | 12 | 23 | 848 1991 CELL 67(6):1047-1058 FU YH; KUHL DPA; PIZZUTI A; PIERETTI M; SUTCLIFFE JS; et al. VARIATION OF THE CGG REPEAT AT THE FRAGILE-X SITE RESULTS IN GENETIC INSTABILITY - RESOLUTION OF THE SHERMAN PARADOX | 432 | 957 |
| 3 | 18 | 37 | 905 1991 SCIENCE 252(5009):1097-1102 OBERLE I; ROUSSEAU F; HEITZ D; KRETZ C; DEVYS D; et al. INSTABILITY OF A 550 BASE PAIR DNA SEGMENT AND ABNORMAL METHYLATION IN FRAGILE X-SYNDROME | 440 | 846 |
| 4 | 10 | 15 | 847 1991 CELL 66(4):817-822 PIERETTI M; ZHANG FP; FU YH; WARREN ST; OOSTRA BA; et al. ABSENCE OF EXPRESSION OF THE FMR-1 GENE IN FRAGILE-X SYNDROME | 333 | 598 |
| 5 | 5 | 13 | 907 1991 SCIENCE 252(5013):1711-1714 KREMER EJ; PRITCHARD M; LYNCH M; YU S; HOLMAN K; et al. MAPPING OF DNA INSTABILITY AT THE FRAGILE-X TO A TRINUCLEOTIDE REPEAT SEQUENCE P(CCG)N | 218 | 584 |
| 6 | 3 | 9 | 906 1991 SCIENCE 252(5009):1179-1181 YU S; PRITCHARD M; KREMER E; LYNCH M; NANCARROW J; et al. FRAGILE-X GENOTYPE CHARACTERIZED BY AN UNSTABLE REGION OF DNA | 295 | 542 |
| 7 | 15 | 28 | 892 1991 NEW ENGLAND JOURNAL OF MEDICINE 325(24):1673-1681 ROUSSEAU F; HEITZ D; BIANCALANA V; BLUMENFELD S; KRETZ C; et al. DIRECT DIAGNOSIS BY DNA ANALYSIS OF THE FRAGILE X-SYNDROME OF MENTAL-RETARDATION | 290 | 445 |
| 8 | 11 | 40 | 288 1985 HUMAN GENETICS 69(4):289-299 SHERMAN SL; JACOBS PA; MORTON NE; FROSTERISKENIUS U; HOWARDPEEBLES PN; et al. FURTHER SEGREGATION ANALYSIS OF THE FRAGILE-X SYNDROME WITH SPECIAL REFERENCE TO TRANSMITTING MALES | 236 | 349 |
| 9 | 15 | 56 | 1091 1993 CELL 74(2):291-298 SIOMI H; SIOMI MC; NUSSBAUM RL; DREYFUSS G THE PROTEIN PRODUCT OF THE FRAGILE-X GENE, FMR1, HAS CHARACTERISTICS OF AN RNA-BINDING PROTEIN | 141 | 334 |
| 10 | 20 | 36 | 1156 1993 NATURE GENETICS 4(4):335-340 DEVYS D; LUTZ Y; ROUYER N; BELLOCQ JP; MANDEL JL THE FMR-1 PROTEIN IS CYTOPLASMIC, MOST ABUNDANT IN NEURONS AND APPEARS NORMAL IN CARRIERS OF A FRAGILE X PREMUTATION | 201 | 294 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 11 | 16 | 27 | 1150 1993 NATURE GENETICS 3(1):31-35 DEBOULLE K; VERKERK AJMH; REYNIERS E; VITS L; HENDRICKX J; et al. A POINT MUTATION IN THE FMR-1 GENE ASSOCIATED WITH FRAGILE-X MENTAL-RETARDATION | 145 | 270 |
| 12 | 16 | 39 | 1227 1994 CELL 77(1):33-39 SIOMI H; CHOI MY; SIOMI MC; NUSSBAUM RL; DREYFUSS G ESSENTIAL ROLE FOR KH DOMAINS IN RNA-BINDING - IMPAIRED RNA-BINDING BY A MUTATION IN THE KH DOMAIN OF FMR1 THAT CAUSES FRAGILE-X SYNDROME | 74 | 266 |
| 13 | 21 | 53 | 1228 1994 CELL 77(6):853-861 KUNST CB; WARREN ST CRYPTIC AND POLAR VARIATION OF THE FRAGILE-X REPEAT COULD RESULT IN PREDISPOSING NORMAL ALLELES | 101 | 244 |
| 14 | 23 | 41 | 1274 1994 NATURE GENETICS 8(1):88-94 EICHLER EE; HOLDEN JJA; POPOVICH BW; REISS AL; SNOW K; et al. LENGTH OF UNINTERRUPTED CGG REPEATS DETERMINES INSTABILITY IN THE FMR1 GENE | 92 | 243 |
| 15 | 11 | 12 | 1461 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(1):196-197 Turner G; Webb T; Wake S; Robinson; H Prevalence of fragile X syndrome | 153 | 235 |
| 16 | 9 | 34 | 845 1991 CELL 64(4):861-866 BELL MV; HIRST MC; NAKAHORI Y; MACKINNON RN; ROCHE A; et al. PHYSICAL MAPPING ACROSS THE FRAGILE-X - HYPERMETHYLATION AND CLINICAL EXPRESSION OF THE FRAGILE-X SYNDROME | 127 | 224 |
| 17 | 10 | 29 | 1705 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(10):5401-5404 Comery TA; Harris JB; Willems PJ; Oostra BA; Irwin SA; et al. Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits | 125 | 220 |
| 18 | 18 | 58 | 1704 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(10):5395-5400 Weiler IJ; Irwin SA; Klintsova AY; Spencer CM; Brazelton AD; et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation | 102 | 192 |
| 19 | 8 | 17 | 1149 1993 NATURE 363(6431):722-724 VERHEIJ C; BAKKER CE; DEGRAAFF E; KEULEMANS J; WILLEMSEN R; et al. CHARACTERIZATION AND LOCALIZATION OF THE FMR-1 GENE-PRODUCT ASSOCIATED WITH FRAGILE-X SYNDROME | 114 | 187 |
| 20 | 9 | 43 | 1516 1996 CELL 85(2):237-245 Musco G; Stier G; Joseph C; Morelli MAC; Nilges M; et al. Three-dimensional structure and stability of the KH domain: Molecular insights into the fragile X syndrome | 22 | 178 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 21 | 15 | 30 | 909 1992 AMERICAN JOURNAL OF HUMAN GENETICS 50(5):968-980 YU S; MULLEY J; LOESCH D; TURNER G; DONNELLY A; et al. FRAGILE-X SYNDROME - UNIQUE GENETICS OF THE HERITABLE UNSTABLE ELEMENT | 103 | 175 |
| 22 | 30 | 38 | 1170 1994 AMERICAN JOURNAL OF HUMAN GENETICS 55(2):225-237 ROUSSEAU F; HEITZ D; TARLETON J; MACPHERSON J; MALMGREN H; et al. A MULTICENTER STUDY ON GENOTYPE-PHENOTYPE CORRELATIONS IN THE FRAGILE-X-SYNDROME, USING DIRECT DIAGNOSIS WITH PROBE STB-12.3 - THE FIRST 2,253 CASES | 129 | 172 |
| 23 | 8 | 33 | 156 1983 NATURE 306(5944):701-704 CAMERINO G; MATTEI MG; MATTEI JF; JAYE M; MANDEL JL CLOSE LINKAGE OF FRAGILE X MENTAL-RETARDATION SYNDROME TO HEMOPHILIA-B AND TRANSMISSION THROUGH A NORMAL-MALE | 78 | 171 |
| 24 | 28 | 44 | 1154 1993 NATURE GENETICS 4(2):143-146 REYNIERS E; VITS L; DEBOULLE K; VANROY B; VANVELZEN D; et al. THE FULL MUTATION IN THE FMR-1 GENE OF MALE FRAGILE-X PATIENTS IS ABSENT IN THEIR SPERM | 96 | 170 |
| 25 | 15 | 42 | 451 1987 GENETICS 117(3):587-599 LAIRD CD PROPOSED MECHANISM OF INHERITANCE AND EXPRESSION OF THE HUMAN FRAGILE-X SYNDROME OF MENTAL-RETARDATION | 92 | 167 |
| 26 | 11 | 14 | 889 1991 NATURE 349(6310):624-626 VINCENT A; HEITZ D; PETIT C; KRETZ C; OBERLE I; et al. ABNORMAL PATTERN DETECTED IN FRAGILE-X PATIENTS BY PULSED-FIELD GEL-ELECTROPHORESIS | 112 | 165 |
| 27 | 23 | 52 | 1229 1994 CELL 78(1):23-33 BAKKER CE; VERHEIJ C; WILLEMSEN R; VANDERHELM R; OERLEMANS F; et al. FMR1 KNOCKOUT MICE - A MODEL TO STUDY FRAGILE-X MENTAL-RETARDATION | 96 | 163 |
| 28 | 25 | 47 | 2134 2001 CELL 107(4):477-487 Brown V; Jin P; Ceman S; Darnell JC; O'Donnell WT; et al. Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome | 80 | 162 |
| 29 | 2 | 18 | 1437 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(11):5199-5203 CHEN XA; MARIAPPAN SVS; CATASTI P; RATLIFF R; MOYZIS RK; et al. HAIRPINS ARE FORMED BY THE SINGLE DNA STRANDS OF THE FRAGILE-X TRIPLET REPEATS - STRUCTURE AND BIOLOGICAL IMPLICATIONS | 33 | 161 |
| 30 | 20 | 33 | 1151 1993 NATURE GENETICS 3(1):36-43 HINDS HL; ASHLEY CT; SUTCLIFFE JS; NELSON DL; WARREN ST; et al. TISSUE SPECIFIC EXPRESSION OF FMR-1 PROVIDES EVIDENCE FOR A FUNCTIONAL-ROLE IN FRAGILE-X SYNDROME | 104 | 160 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 31 | 20 | 55 | 1122 1993 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 270(13):1569-1575 BROWN WT; HOUCK GE; JEZIOROWSKA A; LEVINSON FN; DING XH; et al. RAPID FRAGILE-X CARRIER SCREENING AND PRENATAL-DIAGNOSIS USING A NONRADIOACTIVE PCR TEST | 120 | 159 |
| 32 | 8 | 20 | 1017 1992 NATURE GENETICS 1(4):257-260 RICHARDS RI; HOLMAN K; FRIEND K; KREMER E; HILLEN D; et al. EVIDENCE OF FOUNDER CHROMOSOMES IN FRAGILE-X SYNDROME | 78 | 158 |
| 33 | 17 | 85 | 2135 2001 CELL 107(4):489-499 Darnell JC; Jensen KB; Jin P; Brown V; Warren ST; et al. Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function | 74 | 149 |
| 34 | 10 | 30 | 1282 1994 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91(11):4950-4954 FRY M; LOEB LA THE FRAGILE-X SYNDROME D(CGG)(N) NUCLEOTIDE REPEATS FORM A STABLE TETRAHELICAL STRUCTURE | 39 | 148 |
| 35 | 23 | 59 | 1689 1997 JOURNAL OF NEUROSCIENCE 17(5):1539-1547 Feng Y; Gutekunst CA; Eberhart DE; Yi H; Warren ST; et al. Fragile X mental retardation protein: Nucleocytoplasmic shuttling and association with somatodendritic ribosomes | 85 | 145 |
| 36 | 22 | 34 | 1073 1993 AMERICAN JOURNAL OF HUMAN GENETICS 53(6):1217-1228 SNOW K; DOUD LK; HAGERMAN R; PERGOLIZZI RG; ERSTER SH; et al. ANALYSIS OF A CGG SEQUENCE AT THE FMR-I LOCUS IN FRAGILE-X FAMILIES AND IN THE GENERAL-POPULATION | 102 | 140 |
| 37 | 9 | 33 | 903 1991 SCIENCE 251(4998):1236-1239 HEITZ D; ROUSSEAU F; DEVYS D; SACCONE S; ABDERRAHIM H; et al. ISOLATION OF SEQUENCES THAT SPAN THE FRAGILE-X AND IDENTIFICATION OF A FRAGILE-X RELATED CPG ISLAND | 87 | 139 |
| 38 | 10 | 23 | 1018 1992 NATURE GENETICS 1(5):341-344 GEDEON AK; BAKER E; ROBINSON H; PARTINGTON MW; GROSS B; et al. FRAGILE-X SYNDROME WITHOUT CCG AMPLIFICATION HAS AN FMR1 DELETION | 87 | 138 |
| 39 | 0 | 29 | 1772 1998 JOURNAL OF EXPERIMENTAL MEDICINE 188(12):2335-2342 Sun SQ; Zhang XH; Tough DF; Sprent J Type I interferon-mediated stimulation of T cells by CgG DNA | 0 | 135 |
| 40 | 10 | 39 | 838 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 41(3):289-294 HINTON VJ; BROWN WT; WISNIEWSKI K; RUDELLI RD ANALYSIS OF NEOCORTEX IN 3 MALES WITH THE FRAGILE-X SYNDROME | 92 | 134 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 41 | 26 | 47 | 1693 1997 MOLECULAR CELL 1(1):109-118 Feng Y; Absher D; Eberhart DE; Brown V; Malter HE; et al. FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association | 89 | 134 |
| 42 | 18 | 53 | 1543 1996 HUMAN MOLECULAR GENETICS 5(8):1083-1091 Eberhart DE; Malter HE; Feng Y; Warren ST The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals | 93 | 132 |
| 43 | 24 | 128 | 141 1983 INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY 81:107-143 SUTHERLAND GR THE FRAGILE X-CHROMOSOME | 39 | 131 |
| 44 | 42 | 81 | 1251 1994 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 271(7):536-542 WARREN ST; NELSON DL ADVANCES IN MOLECULAR ANALYSIS OF FRAGILE-X SYNDROME | 74 | 129 |
| 45 | 18 | 52 | 1090 1993 CELL 73(7):1403-1409 HANSEN RS; CANFIELD TK; LAMB MM; GARTLER SM; LAIRD CD ASSOCIATION OF FRAGILE-X SYNDROME WITH DELAYED REPLICATION OF THE FMR1 GENE | 28 | 127 |
| 46 | 1 | 6 | 408 1986 NEW ENGLAND JOURNAL OF MEDICINE 315(10):607-609 TURNER G; ROBINSON H; LAING S; PURVISSMITH S PREVENTIVE SCREENING FOR THE FRAGILE-X SYNDROME | 99 | 126 |
| 47 | 5 | 23 | 72 1982 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 12(3):303-308 BROWN WT; JENKINS EC; FRIEDMAN E; BROOKS J; WISNIEWSKI K; et al. AUTISM IS ASSOCIATED WITH THE FRAGILE-X SYNDROME | 82 | 124 |
| 48 | 18 | 23 | 911 1992 AMERICAN JOURNAL OF HUMAN GENETICS 51(2):299-306 WOHRLE D; KOTZOT D; HIRST MC; MANCA A; KORN B; et al. A MICRODELETION OF LESS THAN 250 KB, INCLUDING THE PROXIMAL PART OF THE FMR-I GENE AND THE FRAGILE-X SITE, IN A MALE WITH THE CLINICAL PHENOTYPE OF FRAGILE-X SYNDROME | 77 | 122 |
| 49 | 19 | 23 | 1153 1993 NATURE GENETICS 4(2):140-142 WOHRLE D; HENNIG I; VOGEL W; STEINBACH P MITOTIC STABILITY OF FRAGILE-X MUTATIONS IN DIFFERENTIATED CELLS INDICATES EARLY POSTCONCEPTIONAL TRINUCLEOTIDE REPEAT EXPANSION | 64 | 122 |
| 50 | 16 | 36 | 1384 1995 EMBO JOURNAL 14(21):5358-5366 ZHANG Y; OCONNOR JP; SIOMI MC; SRINIVASAN S; DUTRA A; et al. THE FRAGILE-X MENTAL-RETARDATION SYNDROME PROTEIN INTERACTS WITH NOVEL HOMOLOGS FXR1 AND FXR2 | 77 | 121 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 51 | 10 | 32 | 1155 1993 NATURE GENETICS 4(3):244-251 ASHLEY CT; SUTCLIFFE JS; KUNST CB; LEINER HA; EICHLER EE; et al. HUMAN AND MURINE FMR-1 - ALTERNATIVE SPLICING AND TRANSLATIONAL INITIATION DOWNSTREAM OF THE CGG-REPEAT | 74 | 120 |
| 52 | 103 | 406 | 172 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 17(1):5-94 OPITZ JM; SUTHERLAND GR CONFERENCE REPORT - INTERNATIONAL WORKSHOP ON THE FRAGILE-X AND X-LINKED MENTAL-RETARDATION | 52 | 116 |
| 53 | 7 | 52 | 238 1985 ACTA NEUROPATHOLOGICA 67(3-4):289-295 RUDELLI RD; BROWN WT; WISNIEWSKI K; JENKINS EC; LAUREKAMIONOWSKA M; et al. ADULT FRAGILE X-SYNDROME - CLINICO-NEUROPATHOLOGIC FINDINGS | 77 | 116 |
| 54 | 12 | 32 | 249 1985 AMERICAN JOURNAL OF MEDICAL GENETICS 21(4):709-717 PEMBREY ME; WINTER RM; DAVIES KE A PRE-MUTATION THAT GENERATES A DEFECT AT CROSSING OVER EXPLAINS THE INHERITANCE OF FRAGILE X MENTAL RETARDATION | 82 | 116 |
| 55 | 18 | 29 | 1245 1994 HUMAN MOLECULAR GENETICS 3(9):1543-1551 SNOW K; TESTER DJ; KRUCKEBERG KE; SCHAID DJ; THIBODEAU SN SEQUENCE-ANALYSIS OF THE FRAGILE-X TRINUCLEOTIDE REPEAT - IMPLICATIONS FOR THE ORIGIN OF THE FRAGILE-X MUTATION | 64 | 115 |
| 56 | 4 | 31 | 840 1991 ANNALS OF NEUROLOGY 29(1):26-32 REISS AL; AYLWARD E; FREUND LS; JOSHI PK; BRYAN RN NEUROANATOMY OF FRAGILE-X-SYNDROME - THE POSTERIOR-FOSSA | 60 | 114 |
| 57 | 34 | 42 | 1322 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(5):1006-1018 ROUSSEAU F; ROUILLARD P; MOREL ML; KHANDJIAN EW; MORGAN K PREVALENCE OF CARRIERS OF PREMUTATION-SIZE ALLELES OF THE FMRI GENE AND IMPLICATIONS FOR THE POPULATION-GENETICS OF THE FRAGILE-X SYNDROME | 86 | 114 |
| 58 | 38 | 118 | 365 1986 ANNUAL REVIEW OF GENETICS 20:109-145 NUSSBAUM RL; LEDBETTER DH FRAGILE-X SYNDROME - A UNIQUE MUTATION IN MAN | 65 | 112 |
| 59 | 13 | 23 | 1035 1993 AMERICAN JOURNAL OF HUMAN GENETICS 52(2):297-304 OUDET C; MORNET E; SERRE JL; THOMAS F; LENTESZENGERLING S; et al. LINKAGE DISEQUILIBRIUM BETWEEN THE FRAGILE-X MUTATION AND 2 CLOSELY LINKED CA REPEATS SUGGESTS THAT FRAGILE-X CHROMOSOMES ARE DERIVED FROM A SMALL NUMBER OF FOUNDER CHROMOSOMES | 58 | 112 |
| 60 | 23 | 34 | 1003 1992 JOURNAL OF MEDICAL GENETICS 29(11):794-801 HEITZ D; DEVYS D; IMBERT G; KRETZ C; MANDEL JL INHERITANCE OF THE FRAGILE-X SYNDROME - SIZE OF THE FRAGILE-X PREMUTATION IS A MAJOR DETERMINANT OF THE TRANSITION TO FULL MUTATION | 84 | 111 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 61 | 18 | 51 | 335 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):341-352 BROWN WT; JENKINS EC; COHEN IL; FISCH GS; WOLFSCHEIN EG; et al. FRAGILE-X AND AUTISM - A MULTICENTER SURVEY | 72 | 110 |
| 62 | 13 | 42 | 337 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):359-374 HAGERMAN RJ; JACKSON AW; LEVITAS A; RIMLAND B; BRADEN M AN ANALYSIS OF AUTISM IN 50 MALES WITH THE FRAGILE-X SYNDROME | 79 | 109 |
| 63 | 17 | 57 | 1563 1996 MOLECULAR AND CELLULAR BIOLOGY 16(7):3825-3832 Siomi MC; Zhang Y; Siomi H; Dreyfuss G Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them | 58 | 109 |
| 64 | 10 | 43 | 2281 2002 GENES & DEVELOPMENT 16(19):2491-2496 Caudy AA; Myers M; Hannon GJ; Hammond SM Fragile X-related protein and VIG associate with the RNA interference machinery | 26 | 109 |
| 65 | 27 | 46 | 1246 1994 HUMAN MOLECULAR GENETICS 3(9):1553-1560 HIRST MC; GREWAL PK; DAVIES KE PRECURSOR ARRAYS FOR TRIPLET REPEAT EXPANSION AT THE FRAGILE-X LOCUS | 56 | 108 |
| 66 | 22 | 31 | 2156 2001 HUMAN MOLECULAR GENETICS 10(4):329-338 Laggerbauer B; Ostareck D; Keidel EM; Ostareck-Lederer A; Fischer U Evidence that fragile X mental retardation protein is a negative regulator of translation | 84 | 106 |
| 67 | 4 | 11 | 397 1986 JOURNAL OF MEDICAL GENETICS 23(5):396-399 WEBB TP; BUNDEY S; THAKE A; TODD J THE FREQUENCY OF THE FRAGILE X-CHROMOSOME AMONG SCHOOLCHILDREN IN COVENTRY | 70 | 105 |
| 68 | 11 | 41 | 1907 1999 JOURNAL OF BIOLOGICAL CHEMISTRY 274(18):12797-12802 Fry M; Loeb LA Human Werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)(n) | 11 | 104 |
| 69 | 5 | 26 | 322 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):157-169 FRYNS JP THE FEMALE AND THE FRAGILE-X - A STUDY OF 144 OBLIGATE FEMALE CARRIERS | 78 | 103 |
| 70 | 5 | 10 | 878 1991 JOURNAL OF MEDICAL GENETICS 28(12):818-823 RICHARDS RI; HOLMAN K; KOZMAN H; KREMER E; LYNCH M; et al. FRAGILE-X SYNDROME - GENETIC LOCALIZATION BY LINKAGE MAPPING OF 2 MICROSATELLITE REPEATS FRAXAC1 AND FRAXAC2 WHICH IMMEDIATELY FLANK THE FRAGILE SITE | 63 | 102 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 71 | 14 | 43 | 1383 1995 EMBO JOURNAL 14(11):2401-2408 SIOMI MC; SIOMI H; SAUER WH; SRINIVASAN S; NUSSBAUM RL; et al. FXR1, AN AUTOSOMAL HOMOLOG OF THE FRAGILE-X MENTAL-RETARDATION GENE | 62 | 102 |
| 72 | 6 | 30 | 1929 1999 NATURE GENETICS 22(1):98-101 Coffee B; Zhang FP; Warren ST; Reines D Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells | 27 | 102 |
| 73 | 8 | 9 | 1421 1995 LANCET 345(8958):1147-1148 WILLEMSEN R; MOHKAMSING S; DEVRIES B; DEVYS D; VANDENOUWELAND A; et al. RAPID ANTIBODY-TEST FOR FRAGILE-X SYNDROME | 81 | 101 |
| 74 | 10 | 31 | 1564 1996 NATURE GENETICS 12(1):91-93 Khandjian EW; Corbin F; Woerly S; Rousseau F The fragile X mental retardation protein is associated with ribosomes | 70 | 101 |
| 75 | 9 | 25 | 1431 1995 NUCLEIC ACIDS RESEARCH 23(20):4202-4209 USDIN K; WOODFORD KJ CGG REPEATS ASSOCIATED WITH DNA INSTABILITY AND CHROMOSOME FRAGILITY FORM STRUCTURES THAT BLOCK DNA-SYNTHESIS IN-VITRO | 22 | 100 |
| 76 | 23 | 41 | 1071 1993 AMERICAN JOURNAL OF HUMAN GENETICS 53(4):800-809 MCCONKIEROSELL A; LACHIEWICZ AM; SPIRIDIGLIOZZI GA; TARLETON J; SCHOENWALD S; et al. EVIDENCE THAT METHYLATION OF THE FMR-I LOCUS IS RESPONSIBLE FOR VARIABLE PHENOTYPIC-EXPRESSION OF THE FRAGILE-X SYNDROME | 64 | 99 |
| 77 | 23 | 47 | 1036 1993 AMERICAN JOURNAL OF HUMAN GENETICS 52(5):884-894 REISS AL; FREUND L; ABRAMS MT; BOEHM C; KAZAZIAN H NEUROBEHAVIORAL EFFECTS OF THE FRAGILE-X PREMUTATION IN ADULT WOMEN - A CONTROLLED-STUDY | 73 | 98 |
| 78 | 11 | 67 | 1420 1995 JOURNAL OF MOLECULAR BIOLOGY 254(4):638-656 KETTANI A; KUMAR RA; PATEL DJ SOLUTION STRUCTURE OF A DNA QUADRUPLEX CONTAINING THE FRAGILE-X SYNDROME TRIPLET REPEAT | 15 | 98 |
| 79 | 20 | 37 | 2137 2001 CELL 107(5):591-603 Zhang YQ; Bailey AM; Matthies HJG; Renden RB; Smith MA; et al. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function | 57 | 98 |
| 80 | 38 | 61 | 1174 1994 AMERICAN JOURNAL OF MEDICAL GENETICS 51(4):298-308 HAGERMAN RJ; HULL CE; SAFANDA JF; CARPENTER I; STALEY LW; et al. HIGH FUNCTIONING FRAGILE-X MALES - DEMONSTRATION OF AN UNMETHYLATED FULLY EXPANDED FMR-1 MUTATION ASSOCIATED WITH PROTEIN EXPRESSION | 69 | 97 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 81 | 11 | 59 | 1994 2000 CELL 100(3):323-332 Lewis HA; Musunuru K; Jensen KB; Edo C; Chen H; et al. Sequence-specific RNA binding by a Nova KH domain: Implications for paraneoplastic disease and the fragile X syndrome | 9 | 97 |
| 82 | 22 | 62 | 2147 2001 EMBO JOURNAL 20(17):4803-4813 Schaeffer C; Bardoni B; Mandel JL; Ehresmann B; Ehresmann C; et al. The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif | 66 | 97 |
| 83 | 3 | 44 | 1403 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(45):27014-27021 KANG SM; OHSHIMA K; SHIMIZU M; AMIRHAERI S; WELLS RD PAUSING OF DNA-SYNTHESIS IN-VITRO AT SPECIFIC LOCI IN CTG AND CGG TRIPLET REPEATS FROM HUMAN HEREDITARY-DISEASE GENES | 16 | 96 |
| 84 | 22 | 40 | 1935 2000 AMERICAN JOURNAL OF HUMAN GENETICS 66(1):6-15 Tassone F; Hagerman RJ; Taylor AK; Gane LW; Godfrey TE; et al. Elevated levels of FMR1 mRNA in carrier males: A new mechanism of involvement in the fragile-X syndrome | 62 | 96 |
| 85 | 7 | 32 | 564 1988 ARCHIVES OF GENERAL PSYCHIATRY 45(1):25-30 REISS AL; HAGERMAN RJ; VINOGRADOV S; ABRAMS M; KING RJ PSYCHIATRIC DISABILITY IN FEMALE CARRIERS OF THE FRAGILE X-CHROMOSOME | 59 | 93 |
| 86 | 13 | 38 | 1667 1997 HUMAN MOLECULAR GENETICS 6(9):1465-1472 Corbin F; Bouillon M; Fortin A; Morin S; Rousseau F; et al. The fragile X mental retardation protein is associated with poly(A)(+) mRNA in actively translating polyribosomes | 70 | 93 |
| 87 | 20 | 36 | 2190 2001 NUCLEIC ACIDS RESEARCH 29(11):2276-2283 Li ZZ; Zhang YY; Ku L; Wilkinson KD; Warren ST; et al. The fragile X mental retardation protein inhibits translation via interacting with mRNA | 72 | 93 |
| 88 | 10 | 15 | 941 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):208-216 DEVYS D; BIANCALANA V; ROUSSEAU F; BOUE J; MANDEL JL; et al. ANALYSIS OF FULL FRAGILE-X MUTATIONS IN FETAL TISSUES AND MONOZYGOTIC TWINS INDICATE THAT ABNORMAL METHYLATION AND SOMATIC HETEROGENEITY ARE ESTABLISHED EARLY IN DEVELOPMENT | 61 | 92 |
| 89 | 30 | 48 | 1250 1994 JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 271(7):507-514 TAYLOR AK; SAFANDA JF; FALL MZ; QUINCE C; LANG KA; et al. MOLECULAR PREDICTORS OF COGNITIVE INVOLVEMENT IN FEMALE CARRIERS OF FRAGILE-X SYNDROME | 80 | 92 |
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| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 91 | 12 | 81 | 1511 1996 BIOCHEMISTRY 35(15):5041-5053 Pearson CE; Sinden RR Alternative structures in duplex DNA formed within the trinucleotide repeats of the myotonic dystrophy and fragile X loci | 4 | 91 |
| 92 | 15 | 79 | 2282 2002 GENES & DEVELOPMENT 16(19):2497-2508 Ishizuka A; Siomi MC; Siomi H A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins | 27 | 91 |
| 93 | 14 | 37 | 1127 1993 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 14(5):328-335 MAZZOCCO MMM; PENNINGTON BF; HAGERMAN RJ THE NEUROCOGNITIVE PHENOTYPE OF FEMALE CARRIERS OF FRAGILE-X - ADDITIONAL EVIDENCE FOR SPECIFICITY | 71 | 90 |
| 94 | 22 | 61 | 1276 1994 NEUROLOGY 44(7):1317-1324 REISS AL; LEE J; FREUND L NEUROANATOMY OF FRAGILE-X SYNDROME - THE TEMPORAL-LOBE | 54 | 89 |
| 95 | 22 | 42 | 1695 1997 NATURE GENETICS 15(2):165-169 Malter HE; Iber JC; Willemsen R; deGraaff E; Tarleton JC; et al. Characterization of the full fragile X syndrome mutation in fetal gametes | 58 | 89 |
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| 97 | 11 | 20 | 880 1991 JOURNAL OF MEDICAL GENETICS 28(12):830-836 ROUSSEAU F; HEITZ D; OBERLE I; MANDEL JL SELECTION IN BLOOD-CELLS FROM FEMALE CARRIERS OF THE FRAGILE-X SYNDROME - INVERSE CORRELATION BETWEEN AGE AND PROPORTION OF ACTIVE X-CHROMOSOMES CARRYING THE FULL MUTATION | 64 | 86 |
| 98 | 6 | 11 | 893 1991 NEW ENGLAND JOURNAL OF MEDICINE 325(24):1720-1722 SUTHERLAND GR; GEDEON A; KORNMAN L; DONNELLY A; BYARD RW; et al. PRENATAL-DIAGNOSIS OF FRAGILE X-SYNDROME BY DIRECT DETECTION OF THE UNSTABLE DNA-SEQUENCE | 62 | 86 |
| 99 | 7 | 27 | 262 1985 CLINICAL GENETICS 27(2):113-117 BLOMQUIST HK; BOHMAN M; EDVINSSON SO; GILLBERG C; GUSTAVSON KH; et al. FREQUENCY OF THE FRAGILE X-SYNDROME IN INFANTILE-AUTISM - A SWEDISH MULTICENTER STUDY | 51 | 85 |
| 100 | 0 | 0 | 28 1981 LANCET 1(8223):780-780 DAKER MG; CHIDIAC P; FEAR CN; BERRY AC FRAGILE X IN A NORMAL-MALE - A CAUTIONARY TALE | 52 | 84 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 101 | 1 | 17 | 21 1981 HUMAN GENETICS 59(2):166-169 MATTEI MG; MATTEI JF; VIDAL I; GIRAUD F EXPRESSION IN LYMPHOCYTE AND FIBROBLAST-CULTURE OF THE FRAGILE X-CHROMOSOME - A NEW TECHNICAL APPROACH | 44 | 83 |
| 102 | 21 | 51 | 1287 1995 AMERICAN JOURNAL OF HUMAN GENETICS 57(2):351-361 ZHONG N; YANG WH; DOBKIN C; BROWN WT FRAGILE-X GENE INSTABILITY - ANCHORING AGGS AND LINKED MICROSATELLITES | 54 | 82 |
| 103 | 53 | 82 | 2020 2000 HUMAN MOLECULAR GENETICS 9(6):901-908 Jin P; Warren ST Understanding the molecular basis of fragile X syndrome | 44 | 82 |
| 104 | 21 | 31 | 1021 1992 PEDIATRICS 89(3):395-400 HAGERMAN RJ; JACKSON C; AMIRI K; SILVERMAN AC; OCONNOR R; et al. GIRLS WITH FRAGILE-X SYNDROME - PHYSICAL AND NEUROCOGNITIVE STATUS AND OUTCOME | 58 | 81 |
| 105 | 7 | 12 | 1134 1993 JOURNAL OF MEDICAL GENETICS 30(6):454-459 JACOBS PA; BULLMAN H; MACPHERSON J; YOUINGS S; ROONEY V; et al. POPULATION STUDIES OF THE FRAGILE-X - A MOLECULAR APPROACH | 55 | 81 |
| 106 | 8 | 32 | 108 1983 AMERICAN JOURNAL OF MEDICAL GENETICS 14(4):699-712 CHUDLEY AE; KNOLL J; GERRARD JW; SHEPEL L; MCGAHEY E; et al. FRAGILE (X) X-LINKED MENTAL-RETARDATION .1. RELATIONSHIP BETWEEN AGE AND INTELLIGENCE AND THE FREQUENCY OF EXPRESSION OF FRAGILE (X)(Q28) | 56 | 80 |
| 107 | 32 | 85 | 482 1987 JOURNAL OF PEDIATRICS 110(6):821-831 CHUDLEY AE; HAGERMAN RJ FRAGILE-X SYNDROME | 53 | 80 |
| 108 | 10 | 29 | 1116 1993 HUMAN MOLECULAR GENETICS 2(9):1429-1435 RICHARDS RI; HOLMAN K; YU S; SUTHERLAND GR FRAGILE-X SYNDROME UNSTABLE ELEMENT, P(CCG)N, AND OTHER SIMPLE TANDEM REPEAT SEQUENCES ARE BINDING-SITES FOR SPECIFIC NUCLEAR PROTEINS | 17 | 80 |
| 109 | 20 | 37 | 1161 1993 PEDIATRICS 91(2):321-329 FREUND LS; REISS AL; ABRAMS MT PSYCHIATRIC-DISORDERS ASSOCIATED WITH FRAGILE-X IN THE YOUNG FEMALE | 58 | 80 |
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| 111 | 7 | 17 | 1024 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(9):4215-4217 MORTON NE; MACPHERSON JN POPULATION-GENETICS OF THE FRAGILE-X SYNDROME - MULTIALLELIC MODEL FOR THE FMR1 LOCUS | 51 | 79 |
| 112 | 21 | 64 | 197 1984 CLINICAL GENETICS 26(6):497-528 FRYNS JP THE FRAGILE X-SYNDROME - A STUDY OF 83 FAMILIES | 45 | 78 |
| 113 | 12 | 46 | 1117 1993 HUMAN MOLECULAR GENETICS 2(10):1659-1665 HORNSTRA IK; NELSON DL; WARREN ST; YANG TP HIGH-RESOLUTION METHYLATION ANALYSIS OF THE FMR1 GENE TRINUCLEOTIDE REPEAT REGION IN FRAGILE X-SYNDROME | 41 | 78 |
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| 116 | 2 | 8 | 77 1982 LANCET 1(8263):100-100 BROWN WT; FRIEDMAN E; JENKINS EC; BROOKS J; WISNIEWSKI K; et al. ASSOCIATION OF FRAGILE-X SYNDROME WITH AUTISM | 50 | 77 |
| 117 | 13 | 27 | 523 1988 AMERICAN JOURNAL OF MEDICAL GENETICS 30(1-2):191-200 KEMPER MB; HAGERMAN RJ; ALTSHULSTARK D COGNITIVE PROFILES OF BOYS WITH THE FRAGILE-X SYNDROME | 58 | 77 |
| 118 | 17 | 46 | 1927 1999 MOLECULAR AND CELLULAR BIOLOGY 19(12):7925-7932 Ceman S; Brown V; Warren ST Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | 50 | 76 |
| 119 | 0 | 3 | 194 1984 CLINICAL GENETICS 25(2):131-134 FRYNS JP; JACOBS J; KLECZKOWSKA A; VANDENBERGHE H THE PSYCHOLOGICAL PROFILE OF THE FRAGILE X-SYNDROME | 57 | 75 |
| 120 | 1 | 10 | 351 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):581-587 GUSTAVSON KH; BLOMQUIST H; HOLMGREN G PREVALENCE OF THE FRAGILE-X SYNDROME IN MENTALLY-RETARDED BOYS IN A SWEDISH COUNTY | 53 | 75 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 121 | 12 | 37 | 902 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(19):8302-8306 POUSTKA A; DIETRICH A; LANGENSTEIN G; TONIOLO D; WARREN ST; et al. PHYSICAL MAP OF HUMAN XQ27-QTER - LOCALIZING THE REGION OF THE FRAGILE-X MUTATION | 7 | 75 |
| 122 | 8 | 24 | 1114 1993 HUMAN MOLECULAR GENETICS 2(4):399-404 VERKERK AJMH; DEGRAAFF E; DEBOULLE K; EICHLER EE; KONECKI DS; et al. ALTERNATIVE SPLICING IN THE FRAGILE X-GENE FMR1 | 0 | 75 |
| 123 | 30 | 52 | 1435 1995 PEDIATRICS 95(5):744-752 BAUMGARDNER TL; REISS AL; FREUND LS; ABRAMS MT SPECIFICATION OF THE NEUROBEHAVIORAL PHENOTYPE IN MALES WITH FRAGILE-X SYNDROME | 49 | 75 |
| 124 | 14 | 42 | 2112 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 98(2):161-167 Irwin SA; Patel B; Idupulapati M; Harris JB; Crisostomo RA; et al. Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination | 48 | 75 |
| 125 | 12 | 32 | 563 1988 AMERICAN JOURNAL ON MENTAL RETARDATION 92(5):436-446 COHEN IL; FISCH GS; SUDHALTER V; WOLFSCHEIN EG; HANSON D; et al. SOCIAL GAZE, SOCIAL AVOIDANCE, AND REPETITIVE BEHAVIOR IN FRAGILE X-MALES - A CONTROLLED-STUDY | 51 | 74 |
| 126 | 12 | 22 | 916 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):35-46 REISS AL; FREUND L BEHAVIORAL-PHENOTYPE OF FRAGILE-X SYNDROME - DSM-III-R AUTISTIC BEHAVIOR IN MALE-CHILDREN | 55 | 74 |
| 127 | 3 | 10 | 2186 2001 NEUROLOGY 57(1):127-130 Hagerman RJ; Leehey M; Heinrichs W; Tassone F; Wilson R; et al. Intention tremor, parkinsonism, and generalized brain atrophy in male carriers of fragile X | 45 | 74 |
| 128 | 2 | 40 | 23 1981 HUMAN GENETICS 59(4):281-289 MATTEI JF; MATTEI MG; AUMERAS C; AUGER M; GIRAUD F X-LINKED MENTAL-RETARDATION WITH THE FRAGILE-X - A STUDY OF 15 FAMILIES | 48 | 72 |
| 129 | 9 | 24 | 241 1985 AMERICAN JOURNAL OF DISEASES OF CHILDREN 139(7):674-678 HAGERMAN R; KEMPER M; HUDSON M LEARNING-DISABILITIES AND ATTENTIONAL PROBLEMS IN BOYS WITH THE FRAGILE X-SYNDROME | 55 | 72 |
| 130 | 10 | 20 | 599 1988 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 18(3):343-354 BREGMAN JD; LECKMAN JF; ORT SI FRAGILE X-SYNDROME - GENETIC PREDISPOSITION TO PSYCHOPATHOLOGY | 44 | 72 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 131 | 0 | 29 | 71 1982 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 12(3):295-301 MERYASH DL; SZYMANSKI LS; GERALD PS INFANTILE-AUTISM ASSOCIATED WITH THE FRAGILE-X SYNDROME | 44 | 71 |
| 132 | 3 | 35 | 236 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(24):7855-7859 SZABO P; PURRELLO M; ROCCHI M; ARCHIDIACONO N; ALHADEFF B; et al. CYTOLOGICAL MAPPING OF THE HUMAN GLUCOSE-6-PHOSPHATE-DEHYDROGENASE GENE DISTAL TO THE FRAGILE-X SITE SUGGESTS A HIGH-RATE OF MEIOTIC RECOMBINATION ACROSS THIS SITE | 17 | 71 |
| 133 | 1 | 2 | 320 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):11-67 TURNER G; OPITZ JM; BROWN WT; DAVIES KE; JACOBS PA; et al. CONFERENCE REPORT - 2ND INTERNATIONAL WORKSHOP ON THE FRAGILE-X AND ON X-LINKED MENTAL-RETARDATION | 51 | 71 |
| 134 | 12 | 37 | 497 1987 SCIENCE 237(4813):420-423 WARREN ST; ZHANG FP; LICAMELI GR; PETERS JF THE FRAGILE-X SITE IN SOMATIC-CELL HYBRIDS - AN APPROACH FOR MOLECULAR-CLONING OF FRAGILE SITES | 30 | 71 |
| 135 | 11 | 23 | 690 1990 AMERICAN JOURNAL ON MENTAL RETARDATION 94(4):431-441 SUDHALTER V; COHEN IL; SILVERMAN W; WOLFSCHEIN EG CONVERSATIONAL ANALYSES OF MALES WITH FRAGILE-X, DOWN SYNDROME, AND AUTISM - COMPARISON OF THE EMERGENCE OF DEVIANT LANGUAGE | 56 | 70 |
| 136 | 3 | 18 | 738 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(10):3856-3860 WARREN ST; KNIGHT SJL; PETERS JF; STAYTON CL; CONSALEZ GG; et al. ISOLATION OF THE HUMAN CHROMOSOMAL BAND XQ28 WITHIN SOMATIC-CELL HYBRIDS BY FRAGILE X-SITE BREAKAGE | 24 | 69 |
| 137 | 8 | 10 | 1007 1992 LANCET 339(8788):271-272 PERGOLIZZI RG; ERSTER SH; GOONEWARDENA P; BROWN WT DETECTION OF FULL FRAGILE-X MUTATION | 48 | 69 |
| 138 | 12 | 37 | 1764 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(25):15521-15527 Brown V; Small K; Lakkis L; Feng Y; Gunter C; et al. Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein | 45 | 69 |
| 139 | 36 | 62 | 2408 2003 CELL 112(3):317-327 Zalfa F; Giorgi M; Primerano B; Moro A; Di Penta A; et al. The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at Synapses | 37 | 69 |
| 140 | 3 | 15 | 132 1983 CLINICAL GENETICS 24(6):393-398 BLOMQUIST HK; GUSTAVSON KH; HOLMGREN G; NORDENSON I; PALSSONSTRAE U FRAGILE X-SYNDROME IN MILDLY MENTALLY-RETARDED CHILDREN IN A NORTHERN SWEDISH COUNTY - A PREVALENCE STUDY | 43 | 68 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 141 | 31 | 61 | 1177 1994 AMERICAN JOURNAL OF MEDICAL GENETICS 51(4):317-327 ABRAMS MT; REISS AL; FREUND LS; BAUMGARDNER TL; CHASE GA; et al. MOLECULAR-NEUROBEHAVIORAL ASSOCIATIONS IN FEMALES WITH THE FRAGILE-X FULL MUTATION | 50 | 67 |
| 142 | 16 | 39 | 1527 1996 EMBO JOURNAL 15(19):5408-5414 Fridell RA; Benson RE; Hua J; Bogerd HP; Cullen BR A nuclear role for the fragile X mental retardation protein | 35 | 67 |
| 143 | 46 | 64 | 1858 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):250-261 Tassone F; Hagerman RJ; Ikle DN; Dyer PN; Lampe M; et al. FMRP expression as a potential prognostic indicator in fragile X syndrome | 60 | 67 |
| 144 | 1 | 1 | 30 1981 LANCET 2(8257):1231-1232 WEBB GC; ROGERS JG; PITT DB; HALLIDAY J; THEOBALD T TRANSMISSION OF FRAGILE (X) (Q27) SITE FROM A MALE | 40 | 66 |
| 145 | 0 | 18 | 40 1982 AMERICAN JOURNAL OF HUMAN GENETICS 34(2):286-293 UCHIDA IA; JOYCE EM ACTIVITY OF THE FRAGILE-X IN HETEROZYGOUS CARRIERS | 0 | 66 |
| 146 | 4 | 22 | 670 1989 SCIENCE 246(4935):1298-1300 SUTHERS GK; CALLEN DF; HYLAND VJ; KOZMAN HM; BAKER E; et al. A NEW DNA MARKER TIGHTLY LINKED TO THE FRAGILE-X LOCUS (FRAXA) | 31 | 66 |
| 147 | 15 | 25 | 1541 1996 HUMAN MOLECULAR GENETICS 5(6):809-813 Tamanini F; Meijer N; Verheij C; Willems PJ; Galjaard H; et al. FMRP is associated to the ribosomes via RNA | 48 | 66 |
| 148 | 2 | 35 | 39 1982 AMERICAN JOURNAL OF DISEASES OF CHILDREN 136(5):392-398 CARPENTER NJ; LEICHTMAN LG; SAY B FRAGILE X-LINKED MENTAL-RETARDATION - A SURVEY OF 65 PATIENTS WITH MENTAL-RETARDATION OF UNKNOWN ORIGIN | 49 | 65 |
| 149 | 4 | 29 | 176 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 17(1):175-194 PARTINGTON MW THE FRAGILE-X SYNDROME .2. PRELIMINARY DATA ON GROWTH AND DEVELOPMENT IN MALES | 52 | 65 |
| 150 | 10 | 29 | 411 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(4):1016-1020 OBERLE I; HEILIG R; MOISAN JP; KLOEPFER C; MATTEI MG; et al. GENETIC-ANALYSIS OF THE FRAGILE-X MENTAL-RETARDATION SYNDROME WITH 2 FLANKING POLYMORPHIC DNA MARKERS | 41 | 65 |
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| 151 | 22 | 49 | 741 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(2):195-202 COHEN IL; SUDHALTER V; PFADT A; JENKINS EC; BROWN WT; et al. WHY ARE AUTISM AND THE FRAGILE-X SYNDROME ASSOCIATED - CONCEPTUAL AND METHODOLOGICAL ISSUES | 34 | 65 |
| 152 | 5 | 42 | 426 1987 AMERICAN JOURNAL ON MENTAL RETARDATION 92(3):272-278 LACHIEWICZ AM; GULLION CM; SPIRIDIGLIOZZI GA; AYLSWORTH AS DECLINING IQS OF YOUNG MALES WITH THE FRAGILE X-SYNDROME | 48 | 64 |
| 153 | 6 | 38 | 680 1990 AMERICAN JOURNAL OF HUMAN GENETICS 47(2):187-195 SUTHERS GK; HYLAND VJ; CALLEN DF; OBERLE I; ROCCHI M; et al. PHYSICAL MAPPING OF NEW DNA PROBES NEAR THE FRAGILE-X MUTATION (FRAXA) BY USING A PANEL OF CELL-LINES | 26 | 64 |
| 154 | 17 | 34 | 745 1991 AMERICAN JOURNAL OF HUMAN GENETICS 49(2):279-288 REISS AL; FREUND L; TSENG JE; JOSHI PK NEUROANATOMY IN FRAGILE-X FEMALES - THE POSTERIOR-FOSSA | 44 | 64 |
| 155 | 12 | 21 | 793 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 38(2-3):283-287 HAGERMAN RJ; AMIRI K; CRONISTER A FRAGILE-X CHECKLIST | 47 | 64 |
| 156 | 7 | 20 | 145 1983 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 4(3):151-158 LEVITAS A; HAGERMAN RJ; BRADEN M; RIMLAND B; MCBOGG P; et al. AUTISM AND THE FRAGILE-X SYNDROME | 49 | 63 |
| 157 | 2 | 32 | 1341 1995 BIOCHEMISTRY 34(39):12803-12811 MITAS M; YU A; DILL J; HAWORTH IS THE TRINUCLEOTIDE REPEAT SEQUENCE D(CGG)(15) FORMS A HEAT-STABLE HAIRPIN CONTAINING G(SYN)CENTER-DOT-G(ANTI) BASE-PAIRS | 15 | 63 |
| 158 | 2 | 54 | 1707 1997 PSYCHIATRY RESEARCH-NEUROIMAGING 75(1):31-48 Kates WR; Abrams MT; Kaufmann WE; Breiter SN; Reiss AL Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome | 20 | 63 |
| 159 | 10 | 36 | 2194 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(13):7101-7106 Greenough WT; Klintsova AY; Irwin SA; Galvez R; Bates KE; et al. Synaptic regulation of protein synthesis and the fragile X protein | 42 | 63 |
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| 161 | 4 | 9 | 80 1982 LANCET 1(8266):273-274 LEJEUNE J IS THE FRAGILE-X SYNDROME AMENABLE TO TREATMENT | 47 | 62 |
| 162 | 10 | 30 | 1006 1992 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 31(6):1141-1148 MAZZOCCO MMM; HAGERMAN RJ; CRONISTERSILVERMAN A; PENNINGTON BF SPECIFIC FRONTAL-LOBE DEFICITS AMONG WOMEN WITH THE FRAGILE-X GENE | 47 | 62 |
| 163 | 12 | 30 | 500 1988 AMERICAN JOURNAL OF HUMAN GENETICS 42(2):380-389 ARVEILER B; OBERLE I; VINCENT A; HOFKER MH; PEARSON PL; et al. GENETIC-MAPPING OF THE XQ27-Q28 REGION - NEW RFLP MARKERS USEFUL FOR DIAGNOSTIC APPLICATIONS IN FRAGILE-X AND HEMOPHILIA-B FAMILIES | 22 | 61 |
| 164 | 22 | 25 | 1133 1993 JOURNAL OF MEDICAL GENETICS 30(5):410-413 OOSTRA BA; JACKY PB; BROWN WT; ROUSSEAU F GUIDELINES FOR THE DIAGNOSIS OF FRAGILE-X SYNDROME | 49 | 61 |
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| 166 | 13 | 40 | 2341 2002 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99(11):7746-7750 Huber KM; Gallagher SM; Warren ST; Bear MF Altered synaptic plasticity in a mouse model of fragile X mental retardation | 35 | 61 |
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| 168 | 8 | 27 | 461 1987 HUMAN GENETICS 77(1):60-65 OBERLE I; CAMERINO G; WROGEMANN K; ARVEILER B; HANAUER A; et al. MULTIPOINT GENETIC-MAPPING OF THE XQ26-Q28 REGION IN FAMILIES WITH FRAGILE-X MENTAL-RETARDATION AND IN NORMAL-FAMILIES REVEALS TIGHT LINKAGE OF MARKERS IN Q26-Q27 | 17 | 60 |
| 169 | 11 | 26 | 722 1990 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 29(6):885-891 REISS AL; FREUND L FRAGILE X SYNDROME, DSM-III-R, AND AUTISM | 42 | 60 |
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| 171 | 9 | 27 | 1167 1993 TRENDS IN BIOCHEMICAL SCIENCES 18(9):331-333 GIBSON TJ; RICE PM; THOMPSON JD; HERINGA J KH DOMAINS WITHIN THE FMR1 SEQUENCE SUGGEST THAT FRAGILE-X SYNDROME STEMS FROM A DEFECT IN RNA-METABOLISM | 22 | 60 |
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| 174 | 5 | 17 | 138 1983 HUMAN GENETICS 64(2):148-150 NUSSBAUM RL; AIRHART SD; LEDBETTER DH EXPRESSION OF THE FRAGILE (X)CHROMOSOME IN AN INTERSPECIFIC SOMATIC-CELL HYBRID | 18 | 58 |
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| 177 | 20 | 28 | 1242 1994 HUMAN MOLECULAR GENETICS 3(3):399-405 MACPHERSON JN; BULLMAN H; YOUINGS SA; JACOBS PA INSERT SIZE AND FLANKING HAPLOTYPE IN FRAGILE-X AND NORMAL-POPULATIONS - POSSIBLE MULTIPLE ORIGINS FOR THE FRAGILE-X MUTATION | 37 | 58 |
| 178 | 71 | 125 | 1335 1995 ANNUAL REVIEW OF NEUROSCIENCE 18:77-99 WARREN ST; ASHLEY CT TRIPLET REPEAT EXPANSION MUTATIONS - THE EXAMPLE OF FRAGILE-X SYNDROME | 26 | 58 |
| 179 | 9 | 37 | 438 1987 CLINICAL GENETICS 32(3):179-186 BORGHGRAEF M; FRYNS JP; DIELKENS A; PYCK K; VANDENBERGHE H FRAGILE (X) SYNDROME - A STUDY OF THE PSYCHOLOGICAL PROFILE IN 23 PREPUBERTAL PATIENTS | 47 | 57 |
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| 194 | 21 | 44 | 623 1989 AMERICAN JOURNAL OF MEDICAL GENETICS 34(2):187-193 EINFELD S; MOLONY H; HALL W AUTISM IS NOT ASSOCIATED WITH THE FRAGILE-X SYNDROME | 31 | 53 |
| 195 | 5 | 34 | 655 1989 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 28(3):422-426 DYKENS EM; HODAPP RM; ORT S; FINUCANE B; SHAPIRO LR; et al. THE TRAJECTORY OF DEVELOPMENT IN MALES WITH FRAGILE-X SYNDROME | 33 | 52 |
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| 202 | 19 | 36 | 2195 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(15):8844-8849 Schenck A; Bardoni B; Moro A; Bagni C; Mandel JL A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P | 27 | 51 |
| 203 | 4 | 13 | 190 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 18(3):483-491 DANIEL A; EKBLOM L; PHILLIPS S CONSTITUTIVE FRAGILE SITES 1P31, 3P14, 6Q26, AND 16Q23 AND THEIR USE AS CONTROLS FOR FALSE-NEGATIVE RESULTS WITH THE FRAGILE(X) | 12 | 50 |
| 204 | 25 | 50 | 1125 1993 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 34(5):673-688 BAILEY A; BOLTON P; BUTLER L; LECOUTEUR A; MURPHY M; et al. PREVALENCE OF THE FRAGILE-X ANOMALY AMONGST AUTISTIC TWINS AND SINGLETONS | 11 | 50 |
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| 206 | 15 | 24 | 1425 1995 NATURE GENETICS 10(4):483-485 LUGENBEEL KA; PEIER AM; CARSON NL; CHUDLEY AE; NELSON DL INTRAGENIC LOSS OF FUNCTION MUTATIONS DEMONSTRATE THE PRIMARY ROLE OF FMR1 IN FRAGILE-X SYNDROME | 34 | 50 |
| 207 | 14 | 28 | 1751 1998 HUMAN MOLECULAR GENETICS 7(1):109-113 Chiurazzi P; Pomponi MG; Willemsen R; Oostra BA; Neri G In vitro reactivation of the FMR1 gene involved in fragile X syndrome | 23 | 50 |
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| 211 | 17 | 40 | 290 1985 HUMAN GENETICS 71(1):11-18 BROWN WT; GROSS AC; CHAN CB; JENKINS EC GENETIC-LINKAGE HETEROGENEITY IN THE FRAGILE X-SYNDROME | 33 | 49 |
| 212 | 6 | 15 | 354 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):643-664 BROWN WT; GROSS AC; CHAN CB; JENKINS EC DNA LINKAGE STUDIES IN THE FRAGILE-X SYNDROME SUGGEST GENETIC-HETEROGENEITY | 36 | 49 |
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| 216 | 0 | 16 | 901 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(3):921-925 OBA T; ANDACHI Y; MUTO A; OSAWA S CGG - AN UNASSIGNED OR NONSENSE CODON IN MYCOPLASMA-CAPRICOLUM | 1 | 49 |
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| 225 | 4 | 17 | 425 1987 AMERICAN JOURNAL OF MENTAL DEFICIENCY 92(2):234-236 DYKENS EM; HODAPP RM; LECKMAN JF STRENGTHS AND WEAKNESSES IN THE INTELLECTUAL-FUNCTIONING OF MALES WITH FRAGILE-X SYNDROME | 26 | 47 |
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| 231 | 15 | 32 | 338 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):375-380 HAGERMAN RJ; CHUDLEY AE; KNOLL JH; JACKSON AW; KEMPER M; et al. AUTISM IN FRAGILE-X FEMALES | 32 | 46 |
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| 237 | 4 | 12 | 339 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):393-401 REISS AL; FEINSTEIN C; TOOMEY KE; GOLDSMITH B; ROSENBAUM K; et al. PSYCHIATRIC DISABILITY ASSOCIATED WITH THE FRAGILE-X CHROMOSOME | 30 | 45 |
| 238 | 6 | 24 | 721 1990 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 29(2):214-219 HODAPP RM; DYKENS EM; HAGERMAN RJ; SCHREINER R; LACHIEWICZ AM; et al. DEVELOPMENTAL IMPLICATIONS OF CHANGING TRAJECTORIES OF IQ IN MALES WITH FRAGILE-X SYNDROME | 32 | 45 |
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| 241 | 53 | 104 | 1761 1998 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 28(5):393-405 Feinstein C; Reiss AL Autism: The point of view from fragile X studies | 18 | 45 |
| 242 | 24 | 74 | 1926 1999 MOLECULAR AND CELLULAR BIOLOGY 19(8):5675-5684 White PJ; Borts RH; Hirst MC Stability of the human fragile X (CGG)(n) triplet repeat array in Saccharomyces cerevisiae deficient in aspects of DNA metabolism | 12 | 45 |
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| 244 | 1 | 2 | 227 1984 LANCET 2(8398):349-349 CHOO KH; GEORGE D; FILBY G; HALLIDAY JL; LEVERSHA M; et al. LINKAGE ANALYSIS OF X-LINKED MENTAL-RETARDATION WITH AND WITHOUT FRAGILE-X USING FACTOR-IX GENE PROBE | 22 | 44 |
| 245 | 6 | 18 | 340 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):403-408 WAHLSTROM J; GILLBERG C; GUSTAVSON KH; HOLMGREN G INFANTILE-AUTISM AND THE FRAGILE-X - A SWEDISH MULTICENTER STUDY | 23 | 44 |
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| 247 | 10 | 20 | 1468 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):241-245 Kooy RF; DHooge R; Reyniers E; Bakker CE; Nagels G; et al. Transgenic mouse model for the fragile X syndrome | 25 | 44 |
| 248 | 3 | 7 | 1490 1996 AMERICAN JOURNAL OF MEDICAL GENETICS 64(2):370-372 Partington MW; Moore DY; Turner GM Confirmation of early menopause in fragile X carriers | 26 | 44 |
| 249 | 10 | 40 | 1781 1998 JOURNAL OF MOLECULAR BIOLOGY 275(1):3-16 Darlow JM; Leach DRF Secondary structures in d(CGG) and d(CCG) repeat tracts | 8 | 44 |
| 250 | 6 | 35 | 1825 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 83(4):248-252 Weiler IJ; Greenough WT Synaptic synthesis of the Fragile X protein: Possible involvement in synapse maturation and elimination | 31 | 44 |
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| 251 | 15 | 58 | 2165 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(19):16439-16446 Kamath-Loeb AS; Loeb LA; Johansson E; Burgers PMJ; Fry M Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)(n) trinucleotide repeat sequence | 4 | 44 |
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| 253 | 2 | 28 | 111 1983 AMERICAN JOURNAL OF MEDICAL GENETICS 15(1):113-119 FILIPPI G; RINALDI A; ARCHIDIACONO N; ROCCHI M; BALAZS I; et al. LINKAGE BETWEEN G6PD AND FRAGILE-X SYNDROME | 19 | 43 |
| 254 | 2 | 16 | 175 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 17(1):159-174 MERYASH DL; CRONK CE; SACHS B; GERALD PS AN ANTHROPOMETRIC STUDY OF MALES WITH THE FRAGILE-X SYNDROME | 26 | 43 |
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| 256 | 5 | 17 | 314 1985 TRENDS IN GENETICS 1(4):108-112 SUTHERLAND GR THE ENIGMA OF THE FRAGILE-X CHROMOSOME | 26 | 43 |
| 257 | 7 | 20 | 421 1987 AMERICAN JOURNAL OF MEDICAL GENETICS 27(2):435-448 MULLEY JC; GEDEON AK; THORN KA; BATES LJ; SUTHERLAND GR LINKAGE AND GENETIC-COUNSELING FOR THE FRAGILE-X USING DNA PROBE-52A, PROBE-F9, PROBE-DX13, AND PROBE-ST14 | 17 | 43 |
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| 260 | 5 | 23 | 701 1990 CLINICAL GENETICS 37(3):167-172 SUTHERLAND GR; BAKER E THE COMMON FRAGILE SITE IN BAND Q27 OF THE HUMAN X-CHROMOSOME IS NOT COINCIDENT WITH THE FRAGILE-X | 30 | 43 |
| # | LCR | NCR | Nodes / Date / Journal / Authors | LCS | GCS |
| 261 | 13 | 18 | 990 1992 HUMAN GENETICS 89(1):114-116 WOHRLE D; HIRST MC; KENNERKNECHT I; DAVIES KE; STEINBACH P GENOTYPE MOSAICISM IN FRAGILE-X FETAL TISSUES | 33 | 43 |
| 262 | 2 | 5 | 1422 1995 LANCET 346(8970):309-310 CONWAY GS; HETTIARACHCHI S; MURRAY A; JACOBS PA FRAGILE-X PREMUTATIONS IN FAMILIAL PREMATURE OVARIAN FAILURE | 21 | 43 |
| 263 | 0 | 19 | 16 1981 CLINICAL GENETICS 19(2):101-110 GUSTAVSON KH; HOLMGREN G; BLOMQUIST HK; MIKKELSEN M; NORDENSON I; et al. FAMILIAL X-LINKED MENTAL-RETARDATION AND FRAGILE X-CHROMOSOMES IN 2 SWEDISH FAMILIES | 28 | 42 |
| 264 | 9 | 25 | 896 1991 NUCLEIC ACIDS RESEARCH 19(12):3283-3288 HIRST MC; RACK K; NAKAHORI Y; ROCHE A; BELL MV; et al. A YAC CONTIG ACROSS THE FRAGILE X SITE DEFINES THE REGION OF FRAGILITY | 16 | 42 |
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