HistCite - index: Fragile X

Tue Aug 24 10:42:17 2004

All papers with "Fragile X" in the title.

Nodes: 2369
Authors: 4634, Journals: 373, Outer References: 14152
Collection span: 1980 - 2004
View: Overview. Sorted by GCS.
Page 2: 1 (1246) 2 (77) 3 (47) 4 (34) 5 (25) 6 (19) 7 (14) 8 (11) 9 (9) 10 (7) 11 (5) 12 (4) 13 (3) 14 (2) 15 (1) 16 (1) 17 (0) 18 (0) 19 (0) 20 (0) 21 (0) 22 (0) 23 (0) 24 (0)

# LCR NCR Nodes / Date / Journal / Authors LCS GCS
101 1 4 28 1981 LANCET 2(8258):1292-1292
JENKINS EC; BROWN WT; DUNCAN CJ; BROOKS J; BENYISHAY M; GIORDANO FM; NITOWSKY HM
FEASIBILITY OF FRAGILE X-CHROMOSOME PRENATAL-DIAGNOSIS DEMONSTRATED
56 77
102 2 8 74 1982 LANCET 1(8263):100-100
BROWN WT; FRIEDMAN E; JENKINS EC; BROOKS J; WISNIEWSKI K; RAGUTHU S; FRENCH JH
ASSOCIATION OF FRAGILE-X SYNDROME WITH AUTISM
49 77
103 12 46 1101 1993 HUMAN MOLECULAR GENETICS 2(10):1659-1665
HORNSTRA IK; NELSON DL; WARREN ST; YANG TP
HIGH-RESOLUTION METHYLATION ANALYSIS OF THE FMR1 GENE TRINUCLEOTIDE REPEAT REGION IN FRAGILE X-SYNDROME
34 77
104 20 37 1143 1993 PEDIATRICS 91(2):321-329
FREUND LS; REISS AL; ABRAMS MT
PSYCHIATRIC-DISORDERS ASSOCIATED WITH FRAGILE-X IN THE YOUNG FEMALE
54 76
105 0 3 191 1984 CLINICAL GENETICS 25(2):131-134
FRYNS JP; JACOBS J; KLECZKOWSKA A; VANDENBERGHE H
THE PSYCHOLOGICAL PROFILE OF THE FRAGILE X-SYNDROME
56 75
106 12 37 894 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(19):8302-8306
POUSTKA A; DIETRICH A; LANGENSTEIN G; TONIOLO D; WARREN ST; LEHRACH H
PHYSICAL MAP OF HUMAN XQ27-QTER - LOCALIZING THE REGION OF THE FRAGILE-X MUTATION
7 75
107 8 24 1098 1993 HUMAN MOLECULAR GENETICS 2(4):399-404
VERKERK AJMH; DEGRAAFF E; DEBOULLE K; EICHLER EE; KONECKI DS; REYNIERS E; MANCA A; POUSTKA A; WILLEMS PJ; NELSON DL; OOSTRA BA
ALTERNATIVE SPLICING IN THE FRAGILE X-GENE FMR1
0 75
108 21 62 2017 2001 EMBO JOURNAL 20(17):4803-4813
Schaeffer C; Bardoni B; Mandel JL; Ehresmann B; Ehresmann C; Moine H
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif
42 75
109 1 10 348 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):581-587
GUSTAVSON KH; BLOMQUIST H; HOLMGREN G
PREVALENCE OF THE FRAGILE-X SYNDROME IN MENTALLY-RETARDED BOYS IN A SWEDISH COUNTY
52 74
110 13 27 519 1988 AMERICAN JOURNAL OF MEDICAL GENETICS 30(1-2):191-200
KEMPER MB; HAGERMAN RJ; ALTSHULSTARK D
COGNITIVE PROFILES OF BOYS WITH THE FRAGILE-X SYNDROME
55 73
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
111 46 82 1894 2000 HUMAN MOLECULAR GENETICS 9(6):901-908
Jin P; Warren ST
Understanding the molecular basis of fragile X syndrome
36 73
112 2 40 20 1981 HUMAN GENETICS 59(4):281-289
MATTEI JF; MATTEI MG; AUMERAS C; AUGER M; GIRAUD F
X-LINKED MENTAL-RETARDATION WITH THE FRAGILE-X - A STUDY OF 15 FAMILIES
48 72
113 0 29 68 1982 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 12(3):295-301
MERYASH DL; SZYMANSKI LS; GERALD PS
INFANTILE-AUTISM ASSOCIATED WITH THE FRAGILE-X SYNDROME
44 71
114 3 35 233 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(24):7855-7859
SZABO P; PURRELLO M; ROCCHI M; ARCHIDIACONO N; ALHADEFF B; FILIPPI G; TONIOLO D; MARTINI G; LUZZATTO L; SINISCALCO M
CYTOLOGICAL MAPPING OF THE HUMAN GLUCOSE-6-PHOSPHATE-DEHYDROGENASE GENE DISTAL TO THE FRAGILE-X SITE SUGGESTS A HIGH-RATE OF MEIOTIC RECOMBINATION ACROSS THIS SITE
17 71
115 9 24 238 1985 AMERICAN JOURNAL OF DISEASES OF CHILDREN 139(7):674-678
HAGERMAN R; KEMPER M; HUDSON M
LEARNING-DISABILITIES AND ATTENTIONAL PROBLEMS IN BOYS WITH THE FRAGILE X-SYNDROME
54 71
116 1 2 317 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):11-67
TURNER G; OPITZ JM; BROWN WT; DAVIES KE; JACOBS PA; JENKINS EC; MIKKELSEN M; PARTINGTON MW; SUTHERLAND GR
CONFERENCE REPORT - 2ND INTERNATIONAL WORKSHOP ON THE FRAGILE-X AND ON X-LINKED MENTAL-RETARDATION
51 71
117 12 37 493 1987 SCIENCE 237(4813):420-423
WARREN ST; ZHANG FP; LICAMELI GR; PETERS JF
THE FRAGILE-X SITE IN SOMATIC-CELL HYBRIDS - AN APPROACH FOR MOLECULAR-CLONING OF FRAGILE SITES
29 71
118 12 32 559 1988 AMERICAN JOURNAL ON MENTAL RETARDATION 92(5):436-446
COHEN IL; FISCH GS; SUDHALTER V; WOLFSCHEIN EG; HANSON D; HAGERMAN R; JENKINS EC; BROWN WT
SOCIAL GAZE, SOCIAL AVOIDANCE, AND REPETITIVE BEHAVIOR IN FRAGILE X-MALES - A CONTROLLED-STUDY
50 71
119 12 22 908 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):35-46
REISS AL; FREUND L
BEHAVIORAL-PHENOTYPE OF FRAGILE-X SYNDROME - DSM-III-R AUTISTIC BEHAVIOR IN MALE-CHILDREN
52 71
120 30 52 1388 1995 PEDIATRICS 95(5):744-752
BAUMGARDNER TL; REISS AL; FREUND LS; ABRAMS MT
SPECIFICATION OF THE NEUROBEHAVIORAL PHENOTYPE IN MALES WITH FRAGILE-X SYNDROME
46 71
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
121 18 37 2007 2001 CELL 107(5):591-603
Zhang YQ; Bailey AM; Matthies HJG; Renden RB; Smith MA; Speese SD; Rubin GM; Broadie K
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
36 71
122 10 20 595 1988 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 18(3):343-354
BREGMAN JD; LECKMAN JF; ORT SI
FRAGILE X-SYNDROME - GENETIC PREDISPOSITION TO PSYCHOPATHOLOGY
42 70
123 22 35 1527 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(3):660-667
deVries BBA; vandenOuweland AMW; Mohkamsing S; Duivenvoorden HJ; Mol E; Gelsema K; vanRijn M; Halley DJJ; Sandkuijl LA; Oostra BA; Tibben A; Niermeijer MF
Screening and diagnosis for the fragile X syndrome among the mentally retarded: An epidemiological and psychological survey
35 70
124 3 18 731 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(10):3856-3860
WARREN ST; KNIGHT SJL; PETERS JF; STAYTON CL; CONSALEZ GG; ZHANG FP
ISOLATION OF THE HUMAN CHROMOSOMAL BAND XQ28 WITHIN SOMATIC-CELL HYBRIDS BY FRAGILE X-SITE BREAKAGE
24 69
125 8 10 998 1992 LANCET 339(8788):271-272
PERGOLIZZI RG; ERSTER SH; GOONEWARDENA P; BROWN WT
DETECTION OF FULL FRAGILE-X MUTATION
46 69
126 3 15 129 1983 CLINICAL GENETICS 24(6):393-398
BLOMQUIST HK; GUSTAVSON KH; HOLMGREN G; NORDENSON I; PALSSONSTRAE U
FRAGILE X-SYNDROME IN MILDLY MENTALLY-RETARDED CHILDREN IN A NORTHERN SWEDISH COUNTY - A PREVALENCE STUDY
42 67
127 18 36 2051 2001 NUCLEIC ACIDS RESEARCH 29(11):2276-2283
Li ZZ; Zhang YY; Ku L; Wilkinson KD; Warren ST; Feng Y
The fragile X mental retardation protein inhibits translation via interacting with mRNA
46 67
128 1 1 27 1981 LANCET 2(8257):1231-1232
WEBB GC; ROGERS JG; PITT DB; HALLIDAY J; THEOBALD T
TRANSMISSION OF FRAGILE (X) (Q27) SITE FROM A MALE
40 66
129 0 18 37 1982 AMERICAN JOURNAL OF HUMAN GENETICS 34(2):286-293
UCHIDA IA; JOYCE EM
ACTIVITY OF THE FRAGILE-X IN HETEROZYGOUS CARRIERS
0 66
130 4 22 664 1989 SCIENCE 246(4935):1298-1300
SUTHERS GK; CALLEN DF; HYLAND VJ; KOZMAN HM; BAKER E; EYRE H; HARPER PS; ROBERTS SH; HORSCAYLA MC; DAVIES KE; BELL MV; SUTHERLAND GR
A NEW DNA MARKER TIGHTLY LINKED TO THE FRAGILE-X LOCUS (FRAXA)
31 66
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
131 9 43 2139 2002 GENES & DEVELOPMENT 16(19):2491-2496
Caudy AA; Myers M; Hannon GJ; Hammond SM
Fragile X-related protein and VIG associate with the RNA interference machinery
14 66
132 2 35 36 1982 AMERICAN JOURNAL OF DISEASES OF CHILDREN 136(5):392-398
CARPENTER NJ; LEICHTMAN LG; SAY B
FRAGILE X-LINKED MENTAL-RETARDATION - A SURVEY OF 65 PATIENTS WITH MENTAL-RETARDATION OF UNKNOWN ORIGIN
48 65
133 4 29 173 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 17(1):175-194
PARTINGTON MW
THE FRAGILE-X SYNDROME .2. PRELIMINARY DATA ON GROWTH AND DEVELOPMENT IN MALES
51 65
134 31 61 1158 1994 AMERICAN JOURNAL OF MEDICAL GENETICS 51(4):317-327
ABRAMS MT; REISS AL; FREUND LS; BAUMGARDNER TL; CHASE GA; DENCKLA MB
MOLECULAR-NEUROBEHAVIORAL ASSOCIATIONS IN FEMALES WITH THE FRAGILE-X FULL MUTATION
48 65
135 15 39 1473 1996 EMBO JOURNAL 15(19):5408-5414
Fridell RA; Benson RE; Hua J; Bogerd HP; Cullen BR
A nuclear role for the fragile X mental retardation protein
32 65
136 10 29 407 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(4):1016-1020
OBERLE I; HEILIG R; MOISAN JP; KLOEPFER C; MATTEI MG; MATTEI JF; BOUE J; FROSTERISKENIUS U; JACOBS PA; LATHROP GM; LALOUEL JM; MANDEL JL
GENETIC-ANALYSIS OF THE FRAGILE-X MENTAL-RETARDATION SYNDROME WITH 2 FLANKING POLYMORPHIC DNA MARKERS
40 64
137 6 38 674 1990 AMERICAN JOURNAL OF HUMAN GENETICS 47(2):187-195
SUTHERS GK; HYLAND VJ; CALLEN DF; OBERLE I; ROCCHI M; THOMAS NS; MORRIS CP; SCHWARTZ CE; SCHMIDT M; ROPERS HH; BAKER E; OOSTRA BA; DAHL N; WILSON PJ; HOPWOOD JJ; SUTHERLAND GR
PHYSICAL MAPPING OF NEW DNA PROBES NEAR THE FRAGILE-X MUTATION (FRAXA) BY USING A PANEL OF CELL-LINES
26 64
138 11 23 684 1990 AMERICAN JOURNAL ON MENTAL RETARDATION 94(4):431-441
SUDHALTER V; COHEN IL; SILVERMAN W; WOLFSCHEIN EG
CONVERSATIONAL ANALYSES OF MALES WITH FRAGILE-X, DOWN SYNDROME, AND AUTISM - COMPARISON OF THE EMERGENCE OF DEVIANT LANGUAGE
51 64
139 22 49 734 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(2):195-202
COHEN IL; SUDHALTER V; PFADT A; JENKINS EC; BROWN WT; VIETZE PM
WHY ARE AUTISM AND THE FRAGILE-X SYNDROME ASSOCIATED - CONCEPTUAL AND METHODOLOGICAL ISSUES
33 64
140 17 34 738 1991 AMERICAN JOURNAL OF HUMAN GENETICS 49(2):279-288
REISS AL; FREUND L; TSENG JE; JOSHI PK
NEUROANATOMY IN FRAGILE-X FEMALES - THE POSTERIOR-FOSSA
43 64
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
141 14 46 1816 1999 MOLECULAR AND CELLULAR BIOLOGY 19(12):7925-7932
Ceman S; Brown V; Warren ST
Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex
35 64
142 14 42 1983 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 98(2):161-167
Irwin SA; Patel B; Idupulapati M; Harris JB; Crisostomo RA; Larsen BP; Kooy F; Willems PJ; Cras P; Kozlowski PB; Swain RA; Weiler IJ; Greenough WT
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination
37 64
143 5 42 422 1987 AMERICAN JOURNAL ON MENTAL RETARDATION 92(3):272-278
LACHIEWICZ AM; GULLION CM; SPIRIDIGLIOZZI GA; AYLSWORTH AS
DECLINING IQS OF YOUNG MALES WITH THE FRAGILE X-SYNDROME
47 63
144 7 20 142 1983 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 4(3):151-158
LEVITAS A; HAGERMAN RJ; BRADEN M; RIMLAND B; MCBOGG P; MATUS I
AUTISM AND THE FRAGILE-X SYNDROME
48 62
145 10 37 1675 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(25):15521-15527
Brown V; Small K; Lakkis L; Feng Y; Gunter C; Wilkinson KD; Warren ST
Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein
36 62
146 44 64 1754 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):250-261
Tassone F; Hagerman RJ; Ikle DN; Dyer PN; Lampe M; Willemsen R; Oostra BA; Taylor AK
FMRP expression as a potential prognostic indicator in fragile X syndrome
52 62
147 4 9 77 1982 LANCET 1(8266):273-274
LEJEUNE J
IS THE FRAGILE-X SYNDROME AMENABLE TO TREATMENT
46 61
148 12 30 496 1988 AMERICAN JOURNAL OF HUMAN GENETICS 42(2):380-389
ARVEILER B; OBERLE I; VINCENT A; HOFKER MH; PEARSON PL; MANDEL JL
GENETIC-MAPPING OF THE XQ27-Q28 REGION - NEW RFLP MARKERS USEFUL FOR DIAGNOSTIC APPLICATIONS IN FRAGILE-X AND HEMOPHILIA-B FAMILIES
22 61
149 10 30 997 1992 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 31(6):1141-1148
MAZZOCCO MMM; HAGERMAN RJ; CRONISTERSILVERMAN A; PENNINGTON BF
SPECIFIC FRONTAL-LOBE DEFICITS AMONG WOMEN WITH THE FRAGILE-X GENE
46 61
150 23 31 1218 1994 HUMAN MOLECULAR GENETICS 3(3):393-398
REISS AL; KAZAZIAN HH; KREBS CM; MCAUGHAN A; BOEHM CD; ABRAMS MT; NELSON DL
FREQUENCY AND STABILITY OF THE FRAGILE-X PREMUTATION
29 61
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
151 4 16 403 1986 NEUROPSYCHOLOGIA 24(3):405-409
MIEZEJESKI CM; JENKINS EC; HILL AL; WISNIEWSKI K; FRENCH JH; BROWN WT
A PROFILE OF COGNITIVE DEFICIT IN FEMALES FROM FRAGILE-X FAMILIES
47 60
152 8 27 457 1987 HUMAN GENETICS 77(1):60-65
OBERLE I; CAMERINO G; WROGEMANN K; ARVEILER B; HANAUER A; RAIMONDI E; MANDEL JL
MULTIPOINT GENETIC-MAPPING OF THE XQ26-Q28 REGION IN FAMILIES WITH FRAGILE-X MENTAL-RETARDATION AND IN NORMAL-FAMILIES REVEALS TIGHT LINKAGE OF MARKERS IN Q26-Q27
17 60
153 12 21 786 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 38(2-3):283-287
HAGERMAN RJ; AMIRI K; CRONISTER A
FRAGILE-X CHECKLIST
45 60
154 17 35 1057 1993 AMERICAN JOURNAL OF HUMAN GENETICS 53(5):1064-1073
LOESCH DZ; HUGGINS R; HAY DA; GEDEON AK; MULLEY JC; SUTHERLAND GR
GENOTYPE-PHENOTYPE RELATIONSHIPS IN FRAGILE-X SYNDROME - A FAMILY STUDY
43 60
155 22 25 1116 1993 JOURNAL OF MEDICAL GENETICS 30(5):410-413
OOSTRA BA; JACKY PB; BROWN WT; ROUSSEAU F
GUIDELINES FOR THE DIAGNOSIS OF FRAGILE-X SYNDROME
45 60
156 1 3 73 1982 LANCET 1(8263):99-100
SHAPIRO LR; WILMOT PL; BRENHOLZ P; LEFF A; MARTINO M; HARRIS G; MAHONEY MJ; HOBBINS JC
PRENATAL-DIAGNOSIS OF FRAGILE-X CHROMOSOME
38 59
157 11 26 716 1990 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 29(6):885-891
REISS AL; FREUND L
FRAGILE X SYNDROME, DSM-III-R, AND AUTISM
40 59
158 9 27 1148 1993 TRENDS IN BIOCHEMICAL SCIENCES 18(9):331-333
GIBSON TJ; RICE PM; THOMPSON JD; HERINGA J
KH DOMAINS WITHIN THE FMR1 SEQUENCE SUGGEST THAT FRAGILE-X SYNDROME STEMS FROM A DEFECT IN RNA-METABOLISM
21 59
159 14 29 1150 1994 AMERICAN JOURNAL OF HUMAN GENETICS 54(3):437-442
KRUYER H; MILA M; GLOVER G; CARBONELL P; BALLESTA F; ESTIVILL X
FRAGILE X SYNDROME AND THE (CGG)(N) MUTATION - 2 FAMILIES WITH DISCORDANT MZ TWINS
20 59
160 5 17 135 1983 HUMAN GENETICS 64(2):148-150
NUSSBAUM RL; AIRHART SD; LEDBETTER DH
EXPRESSION OF THE FRAGILE (X)CHROMOSOME IN AN INTERSPECIFIC SOMATIC-CELL HYBRID
18 58
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
161 7 31 1139 1993 NATURE GENETICS 5(3):248-253
ZHONG N; DOBKIN C; BROWN WT
A COMPLEX MUTABLE POLYMORPHISM LOCATED WITHIN THE FRAGILE X-GENE
29 58
162 14 25 935 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):237-243
RIGGINS GJ; SHERMAN SL; OOSTRA BA; SUTCLIFFE JS; FEITELL D; NELSON DL; VANOOST BA; SMITS APT; RAMOS FJ; PFENDNER E; KUHL DPA; CASKEY CT; WARREN ST
CHARACTERIZATION OF A HIGHLY POLYMORPHIC DINUCLEOTIDE REPEAT 150-KB PROXIMAL TO THE FRAGILE-X SITE
35 57
163 20 28 1219 1994 HUMAN MOLECULAR GENETICS 3(3):399-405
MACPHERSON JN; BULLMAN H; YOUINGS SA; JACOBS PA
INSERT SIZE AND FLANKING HAPLOTYPE IN FRAGILE-X AND NORMAL-POPULATIONS - POSSIBLE MULTIPLE ORIGINS FOR THE FRAGILE-X MUTATION
28 57
164 6 11 225 1984 NEW ENGLAND JOURNAL OF MEDICINE 310(22):1462-1462
WATSON MS; LECKMAN JF; ANNEX B; BREG WR; BOLES D; VOLKMAR FR; COHEN DJ; CARTER C
FRAGILE X IN A SURVEY OF 75 AUTISTIC MALES
34 56
165 12 23 402 1986 NATURE 324(6093):161-163
LEDBETTER DH; LEDBETTER SA; NUSSBAUM RL
IMPLICATIONS OF FRAGILE-X EXPRESSION IN NORMAL MALES FOR THE NATURE OF THE MUTATION
31 56
166 9 37 434 1987 CLINICAL GENETICS 32(3):179-186
BORGHGRAEF M; FRYNS JP; DIELKENS A; PYCK K; VANDENBERGHE H
FRAGILE (X) SYNDROME - A STUDY OF THE PSYCHOLOGICAL PROFILE IN 23 PREPUBERTAL PATIENTS
46 56
167 70 125 1304 1995 ANNUAL REVIEW OF NEUROSCIENCE 18:77-99
WARREN ST; ASHLEY CT
TRIPLET REPEAT EXPANSION MUTATIONS - THE EXAMPLE OF FRAGILE-X SYNDROME
24 56
168 1 7 22 1981 JOURNAL OF MENTAL DEFICIENCY RESEARCH 25(DEC):253-&
RICHARDS BW; SYLVESTER PE; BROOKER C
FRAGILE X-LINKED MENTAL-RETARDATION - THE MARTIN-BELL SYNDROME
36 55
169 0 11 144 1983 JOURNAL OF MEDICAL GENETICS 20(4):280-285
HARRISON CJ; JACK EM; ALLEN TD; HARRIS R
THE FRAGILE X - A SCANNING ELECTRON-MICROSCOPE STUDY
27 54
170 11 14 785 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 38(2-3):269-274
CRONISTER A; SCHREINER R; WITTENBERGER M; AMIRI K; HARRIS K; HAGERMAN RJ
HETEROZYGOUS FRAGILE-X FEMALE - HISTORICAL, PHYSICAL, COGNITIVE, AND CYTOGENETIC FEATURES
36 54
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
171 2 44 1241 1994 JOURNAL OF MOLECULAR BIOLOGY 243(2):143-151
SMITH SS; LAAYOUN A; LINGEMAN RG; BAKER DJ; RILEY J
HYPERMETHYLATION OF TELOMERE-LIKE FOLDBACKS AT CODON-12 OF THE HUMAN C-HA-RAS GENE AND THE TRINUCLEOTIDE REPEAT OF THE FMR-1 GENE OF FRAGILE-X
10 54
172 23 47 453 1987 HUMAN GENETICS 75(4):311-321
BROWN WT; JENKINS EC; GROSS AC; CHAN CB; KRAWCZUN MS; DUNCAN CJ; SKLOWER SL; FISCH GS
FURTHER EVIDENCE FOR GENETIC-HETEROGENEITY IN THE FRAGILE-X SYNDROME
33 53
173 21 44 619 1989 AMERICAN JOURNAL OF MEDICAL GENETICS 34(2):187-193
EINFELD S; MOLONY H; HALL W
AUTISM IS NOT ASSOCIATED WITH THE FRAGILE-X SYNDROME
31 53
174 2 54 1628 1997 PSYCHIATRY RESEARCH-NEUROIMAGING 75(1):31-48
Kates WR; Abrams MT; Kaufmann WE; Breiter SN; Reiss AL
Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome
16 53
175 4 10 252 1985 AMERICAN JOURNAL OF PSYCHIATRY 142(1):108-110
GOLDFINE PE; MCPHERSON PM; HEATH GA; HARDESTY VA; BEAUREGARD LJ; GORDON B
ASSOCIATION OF FRAGILE-X SYNDROME WITH AUTISM
35 52
176 10 29 722 1990 NEUROPSYCHOLOGIA 28(1):9-16
CROWE SF; HAY DA
NEUROPSYCHOLOGICAL DIMENSIONS OF THE FRAGILE X-SYNDROME - SUPPORT FOR A NONDOMINANT HEMISPHERE DYSFUNCTION HYPOTHESIS
36 52
177 15 79 2140 2002 GENES & DEVELOPMENT 16(19):2497-2508
Ishizuka A; Siomi MC; Siomi H
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
15 52
178 12 29 416 1987 AMERICAN JOURNAL OF MEDICAL GENETICS 27(2):401-417
LOESCH DZ; HAY DA; SUTHERLAND GR; HALLIDAY J; JUDGE C; WEBB GC
PHENOTYPIC VARIATION IN MALE-TRANSMITTED FRAGILE-X - GENETIC INFERENCES
36 51
179 4 13 187 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 18(3):483-491
DANIEL A; EKBLOM L; PHILLIPS S
CONSTITUTIVE FRAGILE SITES 1P31, 3P14, 6Q26, AND 16Q23 AND THEIR USE AS CONTROLS FOR FALSE-NEGATIVE RESULTS WITH THE FRAGILE(X)
12 50
180 5 34 650 1989 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 28(3):422-426
DYKENS EM; HODAPP RM; ORT S; FINUCANE B; SHAPIRO LR; LECKMAN JF
THE TRAJECTORY OF DEVELOPMENT IN MALES WITH FRAGILE-X SYNDROME
31 50
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
181 11 16 1102 1993 HUMAN MOLECULAR GENETICS 2(11):1973-1974
TARLETON J; RICHIE R; SCHWARTZ C; RAO K; AYLSWORTH AS; LACHIEWICZ A
AN EXTENSIVE DE-NOVO DELETION REMOVING FMR1 IN A PATIENT WITH MENTAL-RETARDATION AND THE FRAGILE X-SYNDROME PHENOTYPE
29 50
182 2 5 1246 1994 LANCET 344(8935):1500-1500
TURNER G; ROBINSON H; WAKE S; MARTIN N
DIZYGOUS TWINNING AND PREMATURE MENOPAUSE IN FRAGILE-X SYNDROME
31 50
183 134 197 1686 1998 JOURNAL OF MEDICAL GENETICS 35(7):579-589
de Vries BBA; Halley DJJ; Oostra BA; Niermeijer MF
The fragile X syndrome
28 50
184 1 20 48 1982 AMERICAN JOURNAL OF MEDICAL GENETICS 13(2):139-148
BROOKWELL R; DANIEL A; TURNER G; FISHBURN J
THE FRAGILE X(Q27) FORM OF X-LINKED MENTAL-RETARDATION - FUDR AS AN INDUCING AGENT FOR FRA(X)(Q27) EXPRESSION IN LYMPHOCYTES, FIBROBLASTS, AND AMNIOCYTES
23 49
185 8 29 240 1985 AMERICAN JOURNAL OF HUMAN GENETICS 37(3):463-472
MULLIGAN LM; PHILLIPS MA; FORSTERGIBSON CJ; BECKETT J; PARTINGTON MW; SIMPSON NE; HOLDEN JJA; WHITE BN
GENETIC-MAPPING OF DNA SEGMENTS RELATIVE TO THE LOCUS FOR THE FRAGILE-X SYNDROME AT XQ27.3
6 49
186 2 17 286 1985 HUMAN GENETICS 69(4):327-331
MATTEI MG; BAETEMAN MA; HEILIG R; OBERLE I; DAVIES K; MANDEL JL; MATTEI JF
LOCALIZATION BY INSITU HYBRIDIZATION OF THE COAGULATION FACTOR-IX GENE AND OF 2 POLYMORPHIC DNA PROBES WITH RESPECT TO THE FRAGILE-X SITE
8 49
187 17 40 287 1985 HUMAN GENETICS 71(1):11-18
BROWN WT; GROSS AC; CHAN CB; JENKINS EC
GENETIC-LINKAGE HETEROGENEITY IN THE FRAGILE X-SYNDROME
33 49
188 6 15 351 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):643-664
BROWN WT; GROSS AC; CHAN CB; JENKINS EC
DNA LINKAGE STUDIES IN THE FRAGILE-X SYNDROME SUGGEST GENETIC-HETEROGENEITY
36 49
189 12 44 529 1988 AMERICAN JOURNAL OF MEDICAL GENETICS 30(1-2):377-392
HAGERMAN RJ; MURPHY MA; WITTENBERGER MD
A CONTROLLED TRIAL OF STIMULANT MEDICATION IN CHILDREN WITH THE FRAGILE-X SYNDROME
23 49
190 17 32 582 1988 HUMAN GENETICS 78(3):201-205
BROWN WT; GROSS A; CHAN C; JENKINS EC; MANDEL JL; OBERLE I; ARVEILER B; NOVELLI G; THIBODEAU S; HAGERMAN R; SUMMERS K; TURNER G; WHITE BN; MULLIGAN L; FORSTERGIBSON C; HOLDEN JJA; ZOLL B; KRAWCZAK M; GOONEWARDENA P; GUSTAVSON KH; PETTERSSON U; HOLMGREN G; SCHWARTZ C; HOWARDPEEBLES PN; MURPHY P; BREG WR; VEENEMA H; CARPENTER NJ
MULTILOCUS ANALYSIS OF THE FRAGILE-X SYNDROME
33 49
# LCR NCR Nodes / Date / Journal / Authors LCS GCS
191 15 24 1381 1995 NATURE GENETICS 10(4):483-485
LUGENBEEL KA; PEIER AM; CARSON NL; CHUDLEY AE; NELSON DL
INTRAGENIC LOSS OF FUNCTION MUTATIONS DEMONSTRATE THE PRIMARY ROLE OF FMR1 IN FRAGILE-X SYNDROME
30 49
192 10 36 2055 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(13):7101-7106
Greenough WT; Klintsova AY; Irwin SA; Galvez R; Bates KE; Weiler IJ
Synaptic regulation of protein synthesis and the fragile X protein
30 49
193 7 17 733 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(1):108-116
ROUSSEAU F; VINCENT A; RIVELLA S; HEITZ D; TRIBOLI C; MAESTRINI E; WARREN ST; SUTHERS GK; GOODFELLOW P; MANDEL JL; TONIOLO D; OBERLE I
4 CHROMOSOMAL BREAKPOINTS AND 4 NEW PROBES MARK OUT A 10-CM REGION ENCOMPASSING THE FRAGILE-X LOCUS (FRAXA)
25 48
194 9 31 1089 1993 EUROPEAN JOURNAL OF HUMAN GENETICS 1(1):72-79
DEVRIES BBA; WIEGERS AM; DEGRAAFF E; VERKERK AJMH; VANHEMEL JO; HALLEY DJJ; FRYNS JP; CURFS LMG; NIERMEIJER MF; OOSTRA BA
MENTAL STATUS AND FRAGILE-X EXPRESSION IN RELATION TO FMR-1 GENE MUTATION
36 48
195 25 50 1108 1993 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 34(5):673-688
BAILEY A; BOLTON P; BUTLER L; LECOUTEUR A; MURPHY M; SCOTT S; WEBB T; RUTTER M
PREVALENCE OF THE FRAGILE-X ANOMALY AMONGST AUTISTIC TWINS AND SINGLETONS
10 48
196 5 27 1505 1996 NUCLEIC ACIDS RESEARCH 24(4):784-792
Mariappan SVS; Catasti P; Chen X; Ratliff R; Moyzis RK; Bradbury EM; Gupta G
Solution structures of the individual single strands of the fragile X DNA triplets (GCC)(n)center dot(GGC)(n)
10 48
197 2 28 244 1985 AMERICAN JOURNAL OF HUMAN GENETICS 37(6):1192-1205
NUSSBAUM RL; WALMSLEY RM; LESKO JG; AIRHART SD; LEDBETTER DH
THYMIDYLATE SYNTHASE-DEFICIENT CHINESE-HAMSTER CELLS - A SELECTION SYSTEM FOR HUMAN-CHROMOSOME 18 AND EXPERIMENTAL SYSTEM FOR THE STUDY OF THYMIDYLATE SYNTHASE REGULATION AND FRAGILE-X EXPRESSION
6 47
198 2 33 647 1989 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 30(6):845-856
COHEN IL; VIETZE PM; SUDHALTER V; JENKINS EC; BROWN WT
PARENT CHILD DYADIC GAZE PATTERNS IN FRAGILE-X MALES AND IN NON-FRAGILE-X MALES WITH AUTISTIC DISORDER
30 47
199 16 33 735 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(3):460-467
SUTHERS GK; MULLEY JC; VOELCKEL MA; DAHL N; VAISANEN ML; STEINBACH P; GLASS IA; SCHWARTZ CE; VANOOST BA; THIBODEAU SN; HAITES NE; OOSTRA BA; GINE R; CARBALLO M; MORRIS CP; HOPWOOD JJ; SUTHERLAND GR
GENETIC-MAPPING OF NEW DNA PROBES AT XQ27 DEFINES A STRATEGY FOR DNA STUDIES IN THE FRAGILE-X SYNDROME
30 47
200 15 46 1361 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(48):28970-28977
NADEL Y; WEISMANSHOMER P; FRY M
THE FRAGILE-X SYNDROME SINGLE-STRAND D(CGG)(N) NUCLEOTIDE REPEATS READILY FOLD BACK TO FORM UNIMOLECULAR HAIRPIN STRUCTURES
11 47

#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
101	1	4	28 1981 LANCET 2(8258):1292-1292 JENKINS EC; BROWN WT; DUNCAN CJ; BROOKS J; BENYISHAY M; GIORDANO FM; NITOWSKY HM FEASIBILITY OF FRAGILE X-CHROMOSOME PRENATAL-DIAGNOSIS DEMONSTRATED	56	77
102	2	8	74 1982 LANCET 1(8263):100-100 BROWN WT; FRIEDMAN E; JENKINS EC; BROOKS J; WISNIEWSKI K; RAGUTHU S; FRENCH JH ASSOCIATION OF FRAGILE-X SYNDROME WITH AUTISM	49	77
103	12	46	1101 1993 HUMAN MOLECULAR GENETICS 2(10):1659-1665 HORNSTRA IK; NELSON DL; WARREN ST; YANG TP HIGH-RESOLUTION METHYLATION ANALYSIS OF THE FMR1 GENE TRINUCLEOTIDE REPEAT REGION IN FRAGILE X-SYNDROME	34	77
104	20	37	1143 1993 PEDIATRICS 91(2):321-329 FREUND LS; REISS AL; ABRAMS MT PSYCHIATRIC-DISORDERS ASSOCIATED WITH FRAGILE-X IN THE YOUNG FEMALE	54	76
105	0	3	191 1984 CLINICAL GENETICS 25(2):131-134 FRYNS JP; JACOBS J; KLECZKOWSKA A; VANDENBERGHE H THE PSYCHOLOGICAL PROFILE OF THE FRAGILE X-SYNDROME	56	75
106	12	37	894 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(19):8302-8306 POUSTKA A; DIETRICH A; LANGENSTEIN G; TONIOLO D; WARREN ST; LEHRACH H PHYSICAL MAP OF HUMAN XQ27-QTER - LOCALIZING THE REGION OF THE FRAGILE-X MUTATION	7	75
107	8	24	1098 1993 HUMAN MOLECULAR GENETICS 2(4):399-404 VERKERK AJMH; DEGRAAFF E; DEBOULLE K; EICHLER EE; KONECKI DS; REYNIERS E; MANCA A; POUSTKA A; WILLEMS PJ; NELSON DL; OOSTRA BA ALTERNATIVE SPLICING IN THE FRAGILE X-GENE FMR1	0	75
108	21	62	2017 2001 EMBO JOURNAL 20(17):4803-4813 Schaeffer C; Bardoni B; Mandel JL; Ehresmann B; Ehresmann C; Moine H The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif	42	75
109	1	10	348 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):581-587 GUSTAVSON KH; BLOMQUIST H; HOLMGREN G PREVALENCE OF THE FRAGILE-X SYNDROME IN MENTALLY-RETARDED BOYS IN A SWEDISH COUNTY	52	74
110	13	27	519 1988 AMERICAN JOURNAL OF MEDICAL GENETICS 30(1-2):191-200 KEMPER MB; HAGERMAN RJ; ALTSHULSTARK D COGNITIVE PROFILES OF BOYS WITH THE FRAGILE-X SYNDROME	55	73
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
111	46	82	1894 2000 HUMAN MOLECULAR GENETICS 9(6):901-908 Jin P; Warren ST Understanding the molecular basis of fragile X syndrome	36	73
112	2	40	20 1981 HUMAN GENETICS 59(4):281-289 MATTEI JF; MATTEI MG; AUMERAS C; AUGER M; GIRAUD F X-LINKED MENTAL-RETARDATION WITH THE FRAGILE-X - A STUDY OF 15 FAMILIES	48	72
113	0	29	68 1982 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 12(3):295-301 MERYASH DL; SZYMANSKI LS; GERALD PS INFANTILE-AUTISM ASSOCIATED WITH THE FRAGILE-X SYNDROME	44	71
114	3	35	233 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(24):7855-7859 SZABO P; PURRELLO M; ROCCHI M; ARCHIDIACONO N; ALHADEFF B; FILIPPI G; TONIOLO D; MARTINI G; LUZZATTO L; SINISCALCO M CYTOLOGICAL MAPPING OF THE HUMAN GLUCOSE-6-PHOSPHATE-DEHYDROGENASE GENE DISTAL TO THE FRAGILE-X SITE SUGGESTS A HIGH-RATE OF MEIOTIC RECOMBINATION ACROSS THIS SITE	17	71
115	9	24	238 1985 AMERICAN JOURNAL OF DISEASES OF CHILDREN 139(7):674-678 HAGERMAN R; KEMPER M; HUDSON M LEARNING-DISABILITIES AND ATTENTIONAL PROBLEMS IN BOYS WITH THE FRAGILE X-SYNDROME	54	71
116	1	2	317 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):11-67 TURNER G; OPITZ JM; BROWN WT; DAVIES KE; JACOBS PA; JENKINS EC; MIKKELSEN M; PARTINGTON MW; SUTHERLAND GR CONFERENCE REPORT - 2ND INTERNATIONAL WORKSHOP ON THE FRAGILE-X AND ON X-LINKED MENTAL-RETARDATION	51	71
117	12	37	493 1987 SCIENCE 237(4813):420-423 WARREN ST; ZHANG FP; LICAMELI GR; PETERS JF THE FRAGILE-X SITE IN SOMATIC-CELL HYBRIDS - AN APPROACH FOR MOLECULAR-CLONING OF FRAGILE SITES	29	71
118	12	32	559 1988 AMERICAN JOURNAL ON MENTAL RETARDATION 92(5):436-446 COHEN IL; FISCH GS; SUDHALTER V; WOLFSCHEIN EG; HANSON D; HAGERMAN R; JENKINS EC; BROWN WT SOCIAL GAZE, SOCIAL AVOIDANCE, AND REPETITIVE BEHAVIOR IN FRAGILE X-MALES - A CONTROLLED-STUDY	50	71
119	12	22	908 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):35-46 REISS AL; FREUND L BEHAVIORAL-PHENOTYPE OF FRAGILE-X SYNDROME - DSM-III-R AUTISTIC BEHAVIOR IN MALE-CHILDREN	52	71
120	30	52	1388 1995 PEDIATRICS 95(5):744-752 BAUMGARDNER TL; REISS AL; FREUND LS; ABRAMS MT SPECIFICATION OF THE NEUROBEHAVIORAL PHENOTYPE IN MALES WITH FRAGILE-X SYNDROME	46	71
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
121	18	37	2007 2001 CELL 107(5):591-603 Zhang YQ; Bailey AM; Matthies HJG; Renden RB; Smith MA; Speese SD; Rubin GM; Broadie K Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function	36	71
122	10	20	595 1988 JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 18(3):343-354 BREGMAN JD; LECKMAN JF; ORT SI FRAGILE X-SYNDROME - GENETIC PREDISPOSITION TO PSYCHOPATHOLOGY	42	70
123	22	35	1527 1997 AMERICAN JOURNAL OF HUMAN GENETICS 61(3):660-667 deVries BBA; vandenOuweland AMW; Mohkamsing S; Duivenvoorden HJ; Mol E; Gelsema K; vanRijn M; Halley DJJ; Sandkuijl LA; Oostra BA; Tibben A; Niermeijer MF Screening and diagnosis for the fragile X syndrome among the mentally retarded: An epidemiological and psychological survey	35	70
124	3	18	731 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(10):3856-3860 WARREN ST; KNIGHT SJL; PETERS JF; STAYTON CL; CONSALEZ GG; ZHANG FP ISOLATION OF THE HUMAN CHROMOSOMAL BAND XQ28 WITHIN SOMATIC-CELL HYBRIDS BY FRAGILE X-SITE BREAKAGE	24	69
125	8	10	998 1992 LANCET 339(8788):271-272 PERGOLIZZI RG; ERSTER SH; GOONEWARDENA P; BROWN WT DETECTION OF FULL FRAGILE-X MUTATION	46	69
126	3	15	129 1983 CLINICAL GENETICS 24(6):393-398 BLOMQUIST HK; GUSTAVSON KH; HOLMGREN G; NORDENSON I; PALSSONSTRAE U FRAGILE X-SYNDROME IN MILDLY MENTALLY-RETARDED CHILDREN IN A NORTHERN SWEDISH COUNTY - A PREVALENCE STUDY	42	67
127	18	36	2051 2001 NUCLEIC ACIDS RESEARCH 29(11):2276-2283 Li ZZ; Zhang YY; Ku L; Wilkinson KD; Warren ST; Feng Y The fragile X mental retardation protein inhibits translation via interacting with mRNA	46	67
128	1	1	27 1981 LANCET 2(8257):1231-1232 WEBB GC; ROGERS JG; PITT DB; HALLIDAY J; THEOBALD T TRANSMISSION OF FRAGILE (X) (Q27) SITE FROM A MALE	40	66
129	0	18	37 1982 AMERICAN JOURNAL OF HUMAN GENETICS 34(2):286-293 UCHIDA IA; JOYCE EM ACTIVITY OF THE FRAGILE-X IN HETEROZYGOUS CARRIERS	0	66
130	4	22	664 1989 SCIENCE 246(4935):1298-1300 SUTHERS GK; CALLEN DF; HYLAND VJ; KOZMAN HM; BAKER E; EYRE H; HARPER PS; ROBERTS SH; HORSCAYLA MC; DAVIES KE; BELL MV; SUTHERLAND GR A NEW DNA MARKER TIGHTLY LINKED TO THE FRAGILE-X LOCUS (FRAXA)	31	66
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
131	9	43	2139 2002 GENES & DEVELOPMENT 16(19):2491-2496 Caudy AA; Myers M; Hannon GJ; Hammond SM Fragile X-related protein and VIG associate with the RNA interference machinery	14	66
132	2	35	36 1982 AMERICAN JOURNAL OF DISEASES OF CHILDREN 136(5):392-398 CARPENTER NJ; LEICHTMAN LG; SAY B FRAGILE X-LINKED MENTAL-RETARDATION - A SURVEY OF 65 PATIENTS WITH MENTAL-RETARDATION OF UNKNOWN ORIGIN	48	65
133	4	29	173 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 17(1):175-194 PARTINGTON MW THE FRAGILE-X SYNDROME .2. PRELIMINARY DATA ON GROWTH AND DEVELOPMENT IN MALES	51	65
134	31	61	1158 1994 AMERICAN JOURNAL OF MEDICAL GENETICS 51(4):317-327 ABRAMS MT; REISS AL; FREUND LS; BAUMGARDNER TL; CHASE GA; DENCKLA MB MOLECULAR-NEUROBEHAVIORAL ASSOCIATIONS IN FEMALES WITH THE FRAGILE-X FULL MUTATION	48	65
135	15	39	1473 1996 EMBO JOURNAL 15(19):5408-5414 Fridell RA; Benson RE; Hua J; Bogerd HP; Cullen BR A nuclear role for the fragile X mental retardation protein	32	65
136	10	29	407 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(4):1016-1020 OBERLE I; HEILIG R; MOISAN JP; KLOEPFER C; MATTEI MG; MATTEI JF; BOUE J; FROSTERISKENIUS U; JACOBS PA; LATHROP GM; LALOUEL JM; MANDEL JL GENETIC-ANALYSIS OF THE FRAGILE-X MENTAL-RETARDATION SYNDROME WITH 2 FLANKING POLYMORPHIC DNA MARKERS	40	64
137	6	38	674 1990 AMERICAN JOURNAL OF HUMAN GENETICS 47(2):187-195 SUTHERS GK; HYLAND VJ; CALLEN DF; OBERLE I; ROCCHI M; THOMAS NS; MORRIS CP; SCHWARTZ CE; SCHMIDT M; ROPERS HH; BAKER E; OOSTRA BA; DAHL N; WILSON PJ; HOPWOOD JJ; SUTHERLAND GR PHYSICAL MAPPING OF NEW DNA PROBES NEAR THE FRAGILE-X MUTATION (FRAXA) BY USING A PANEL OF CELL-LINES	26	64
138	11	23	684 1990 AMERICAN JOURNAL ON MENTAL RETARDATION 94(4):431-441 SUDHALTER V; COHEN IL; SILVERMAN W; WOLFSCHEIN EG CONVERSATIONAL ANALYSES OF MALES WITH FRAGILE-X, DOWN SYNDROME, AND AUTISM - COMPARISON OF THE EMERGENCE OF DEVIANT LANGUAGE	51	64
139	22	49	734 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(2):195-202 COHEN IL; SUDHALTER V; PFADT A; JENKINS EC; BROWN WT; VIETZE PM WHY ARE AUTISM AND THE FRAGILE-X SYNDROME ASSOCIATED - CONCEPTUAL AND METHODOLOGICAL ISSUES	33	64
140	17	34	738 1991 AMERICAN JOURNAL OF HUMAN GENETICS 49(2):279-288 REISS AL; FREUND L; TSENG JE; JOSHI PK NEUROANATOMY IN FRAGILE-X FEMALES - THE POSTERIOR-FOSSA	43	64
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
141	14	46	1816 1999 MOLECULAR AND CELLULAR BIOLOGY 19(12):7925-7932 Ceman S; Brown V; Warren ST Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex	35	64
142	14	42	1983 2001 AMERICAN JOURNAL OF MEDICAL GENETICS 98(2):161-167 Irwin SA; Patel B; Idupulapati M; Harris JB; Crisostomo RA; Larsen BP; Kooy F; Willems PJ; Cras P; Kozlowski PB; Swain RA; Weiler IJ; Greenough WT Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination	37	64
143	5	42	422 1987 AMERICAN JOURNAL ON MENTAL RETARDATION 92(3):272-278 LACHIEWICZ AM; GULLION CM; SPIRIDIGLIOZZI GA; AYLSWORTH AS DECLINING IQS OF YOUNG MALES WITH THE FRAGILE X-SYNDROME	47	63
144	7	20	142 1983 JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 4(3):151-158 LEVITAS A; HAGERMAN RJ; BRADEN M; RIMLAND B; MCBOGG P; MATUS I AUTISM AND THE FRAGILE-X SYNDROME	48	62
145	10	37	1675 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(25):15521-15527 Brown V; Small K; Lakkis L; Feng Y; Gunter C; Wilkinson KD; Warren ST Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein	36	62
146	44	64	1754 1999 AMERICAN JOURNAL OF MEDICAL GENETICS 84(3):250-261 Tassone F; Hagerman RJ; Ikle DN; Dyer PN; Lampe M; Willemsen R; Oostra BA; Taylor AK FMRP expression as a potential prognostic indicator in fragile X syndrome	52	62
147	4	9	77 1982 LANCET 1(8266):273-274 LEJEUNE J IS THE FRAGILE-X SYNDROME AMENABLE TO TREATMENT	46	61
148	12	30	496 1988 AMERICAN JOURNAL OF HUMAN GENETICS 42(2):380-389 ARVEILER B; OBERLE I; VINCENT A; HOFKER MH; PEARSON PL; MANDEL JL GENETIC-MAPPING OF THE XQ27-Q28 REGION - NEW RFLP MARKERS USEFUL FOR DIAGNOSTIC APPLICATIONS IN FRAGILE-X AND HEMOPHILIA-B FAMILIES	22	61
149	10	30	997 1992 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 31(6):1141-1148 MAZZOCCO MMM; HAGERMAN RJ; CRONISTERSILVERMAN A; PENNINGTON BF SPECIFIC FRONTAL-LOBE DEFICITS AMONG WOMEN WITH THE FRAGILE-X GENE	46	61
150	23	31	1218 1994 HUMAN MOLECULAR GENETICS 3(3):393-398 REISS AL; KAZAZIAN HH; KREBS CM; MCAUGHAN A; BOEHM CD; ABRAMS MT; NELSON DL FREQUENCY AND STABILITY OF THE FRAGILE-X PREMUTATION	29	61
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
151	4	16	403 1986 NEUROPSYCHOLOGIA 24(3):405-409 MIEZEJESKI CM; JENKINS EC; HILL AL; WISNIEWSKI K; FRENCH JH; BROWN WT A PROFILE OF COGNITIVE DEFICIT IN FEMALES FROM FRAGILE-X FAMILIES	47	60
152	8	27	457 1987 HUMAN GENETICS 77(1):60-65 OBERLE I; CAMERINO G; WROGEMANN K; ARVEILER B; HANAUER A; RAIMONDI E; MANDEL JL MULTIPOINT GENETIC-MAPPING OF THE XQ26-Q28 REGION IN FAMILIES WITH FRAGILE-X MENTAL-RETARDATION AND IN NORMAL-FAMILIES REVEALS TIGHT LINKAGE OF MARKERS IN Q26-Q27	17	60
153	12	21	786 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 38(2-3):283-287 HAGERMAN RJ; AMIRI K; CRONISTER A FRAGILE-X CHECKLIST	45	60
154	17	35	1057 1993 AMERICAN JOURNAL OF HUMAN GENETICS 53(5):1064-1073 LOESCH DZ; HUGGINS R; HAY DA; GEDEON AK; MULLEY JC; SUTHERLAND GR GENOTYPE-PHENOTYPE RELATIONSHIPS IN FRAGILE-X SYNDROME - A FAMILY STUDY	43	60
155	22	25	1116 1993 JOURNAL OF MEDICAL GENETICS 30(5):410-413 OOSTRA BA; JACKY PB; BROWN WT; ROUSSEAU F GUIDELINES FOR THE DIAGNOSIS OF FRAGILE-X SYNDROME	45	60
156	1	3	73 1982 LANCET 1(8263):99-100 SHAPIRO LR; WILMOT PL; BRENHOLZ P; LEFF A; MARTINO M; HARRIS G; MAHONEY MJ; HOBBINS JC PRENATAL-DIAGNOSIS OF FRAGILE-X CHROMOSOME	38	59
157	11	26	716 1990 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 29(6):885-891 REISS AL; FREUND L FRAGILE X SYNDROME, DSM-III-R, AND AUTISM	40	59
158	9	27	1148 1993 TRENDS IN BIOCHEMICAL SCIENCES 18(9):331-333 GIBSON TJ; RICE PM; THOMPSON JD; HERINGA J KH DOMAINS WITHIN THE FMR1 SEQUENCE SUGGEST THAT FRAGILE-X SYNDROME STEMS FROM A DEFECT IN RNA-METABOLISM	21	59
159	14	29	1150 1994 AMERICAN JOURNAL OF HUMAN GENETICS 54(3):437-442 KRUYER H; MILA M; GLOVER G; CARBONELL P; BALLESTA F; ESTIVILL X FRAGILE X SYNDROME AND THE (CGG)(N) MUTATION - 2 FAMILIES WITH DISCORDANT MZ TWINS	20	59
160	5	17	135 1983 HUMAN GENETICS 64(2):148-150 NUSSBAUM RL; AIRHART SD; LEDBETTER DH EXPRESSION OF THE FRAGILE (X)CHROMOSOME IN AN INTERSPECIFIC SOMATIC-CELL HYBRID	18	58
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
161	7	31	1139 1993 NATURE GENETICS 5(3):248-253 ZHONG N; DOBKIN C; BROWN WT A COMPLEX MUTABLE POLYMORPHISM LOCATED WITHIN THE FRAGILE X-GENE	29	58
162	14	25	935 1992 AMERICAN JOURNAL OF MEDICAL GENETICS 43(1-2):237-243 RIGGINS GJ; SHERMAN SL; OOSTRA BA; SUTCLIFFE JS; FEITELL D; NELSON DL; VANOOST BA; SMITS APT; RAMOS FJ; PFENDNER E; KUHL DPA; CASKEY CT; WARREN ST CHARACTERIZATION OF A HIGHLY POLYMORPHIC DINUCLEOTIDE REPEAT 150-KB PROXIMAL TO THE FRAGILE-X SITE	35	57
163	20	28	1219 1994 HUMAN MOLECULAR GENETICS 3(3):399-405 MACPHERSON JN; BULLMAN H; YOUINGS SA; JACOBS PA INSERT SIZE AND FLANKING HAPLOTYPE IN FRAGILE-X AND NORMAL-POPULATIONS - POSSIBLE MULTIPLE ORIGINS FOR THE FRAGILE-X MUTATION	28	57
164	6	11	225 1984 NEW ENGLAND JOURNAL OF MEDICINE 310(22):1462-1462 WATSON MS; LECKMAN JF; ANNEX B; BREG WR; BOLES D; VOLKMAR FR; COHEN DJ; CARTER C FRAGILE X IN A SURVEY OF 75 AUTISTIC MALES	34	56
165	12	23	402 1986 NATURE 324(6093):161-163 LEDBETTER DH; LEDBETTER SA; NUSSBAUM RL IMPLICATIONS OF FRAGILE-X EXPRESSION IN NORMAL MALES FOR THE NATURE OF THE MUTATION	31	56
166	9	37	434 1987 CLINICAL GENETICS 32(3):179-186 BORGHGRAEF M; FRYNS JP; DIELKENS A; PYCK K; VANDENBERGHE H FRAGILE (X) SYNDROME - A STUDY OF THE PSYCHOLOGICAL PROFILE IN 23 PREPUBERTAL PATIENTS	46	56
167	70	125	1304 1995 ANNUAL REVIEW OF NEUROSCIENCE 18:77-99 WARREN ST; ASHLEY CT TRIPLET REPEAT EXPANSION MUTATIONS - THE EXAMPLE OF FRAGILE-X SYNDROME	24	56
168	1	7	22 1981 JOURNAL OF MENTAL DEFICIENCY RESEARCH 25(DEC):253-& RICHARDS BW; SYLVESTER PE; BROOKER C FRAGILE X-LINKED MENTAL-RETARDATION - THE MARTIN-BELL SYNDROME	36	55
169	0	11	144 1983 JOURNAL OF MEDICAL GENETICS 20(4):280-285 HARRISON CJ; JACK EM; ALLEN TD; HARRIS R THE FRAGILE X - A SCANNING ELECTRON-MICROSCOPE STUDY	27	54
170	11	14	785 1991 AMERICAN JOURNAL OF MEDICAL GENETICS 38(2-3):269-274 CRONISTER A; SCHREINER R; WITTENBERGER M; AMIRI K; HARRIS K; HAGERMAN RJ HETEROZYGOUS FRAGILE-X FEMALE - HISTORICAL, PHYSICAL, COGNITIVE, AND CYTOGENETIC FEATURES	36	54
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
171	2	44	1241 1994 JOURNAL OF MOLECULAR BIOLOGY 243(2):143-151 SMITH SS; LAAYOUN A; LINGEMAN RG; BAKER DJ; RILEY J HYPERMETHYLATION OF TELOMERE-LIKE FOLDBACKS AT CODON-12 OF THE HUMAN C-HA-RAS GENE AND THE TRINUCLEOTIDE REPEAT OF THE FMR-1 GENE OF FRAGILE-X	10	54
172	23	47	453 1987 HUMAN GENETICS 75(4):311-321 BROWN WT; JENKINS EC; GROSS AC; CHAN CB; KRAWCZUN MS; DUNCAN CJ; SKLOWER SL; FISCH GS FURTHER EVIDENCE FOR GENETIC-HETEROGENEITY IN THE FRAGILE-X SYNDROME	33	53
173	21	44	619 1989 AMERICAN JOURNAL OF MEDICAL GENETICS 34(2):187-193 EINFELD S; MOLONY H; HALL W AUTISM IS NOT ASSOCIATED WITH THE FRAGILE-X SYNDROME	31	53
174	2	54	1628 1997 PSYCHIATRY RESEARCH-NEUROIMAGING 75(1):31-48 Kates WR; Abrams MT; Kaufmann WE; Breiter SN; Reiss AL Reliability and validity of MRI measurement of the amygdala and hippocampus in children with fragile X syndrome	16	53
175	4	10	252 1985 AMERICAN JOURNAL OF PSYCHIATRY 142(1):108-110 GOLDFINE PE; MCPHERSON PM; HEATH GA; HARDESTY VA; BEAUREGARD LJ; GORDON B ASSOCIATION OF FRAGILE-X SYNDROME WITH AUTISM	35	52
176	10	29	722 1990 NEUROPSYCHOLOGIA 28(1):9-16 CROWE SF; HAY DA NEUROPSYCHOLOGICAL DIMENSIONS OF THE FRAGILE X-SYNDROME - SUPPORT FOR A NONDOMINANT HEMISPHERE DYSFUNCTION HYPOTHESIS	36	52
177	15	79	2140 2002 GENES & DEVELOPMENT 16(19):2497-2508 Ishizuka A; Siomi MC; Siomi H A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins	15	52
178	12	29	416 1987 AMERICAN JOURNAL OF MEDICAL GENETICS 27(2):401-417 LOESCH DZ; HAY DA; SUTHERLAND GR; HALLIDAY J; JUDGE C; WEBB GC PHENOTYPIC VARIATION IN MALE-TRANSMITTED FRAGILE-X - GENETIC INFERENCES	36	51
179	4	13	187 1984 AMERICAN JOURNAL OF MEDICAL GENETICS 18(3):483-491 DANIEL A; EKBLOM L; PHILLIPS S CONSTITUTIVE FRAGILE SITES 1P31, 3P14, 6Q26, AND 16Q23 AND THEIR USE AS CONTROLS FOR FALSE-NEGATIVE RESULTS WITH THE FRAGILE(X)	12	50
180	5	34	650 1989 JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY 28(3):422-426 DYKENS EM; HODAPP RM; ORT S; FINUCANE B; SHAPIRO LR; LECKMAN JF THE TRAJECTORY OF DEVELOPMENT IN MALES WITH FRAGILE-X SYNDROME	31	50
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
181	11	16	1102 1993 HUMAN MOLECULAR GENETICS 2(11):1973-1974 TARLETON J; RICHIE R; SCHWARTZ C; RAO K; AYLSWORTH AS; LACHIEWICZ A AN EXTENSIVE DE-NOVO DELETION REMOVING FMR1 IN A PATIENT WITH MENTAL-RETARDATION AND THE FRAGILE X-SYNDROME PHENOTYPE	29	50
182	2	5	1246 1994 LANCET 344(8935):1500-1500 TURNER G; ROBINSON H; WAKE S; MARTIN N DIZYGOUS TWINNING AND PREMATURE MENOPAUSE IN FRAGILE-X SYNDROME	31	50
183	134	197	1686 1998 JOURNAL OF MEDICAL GENETICS 35(7):579-589 de Vries BBA; Halley DJJ; Oostra BA; Niermeijer MF The fragile X syndrome	28	50
184	1	20	48 1982 AMERICAN JOURNAL OF MEDICAL GENETICS 13(2):139-148 BROOKWELL R; DANIEL A; TURNER G; FISHBURN J THE FRAGILE X(Q27) FORM OF X-LINKED MENTAL-RETARDATION - FUDR AS AN INDUCING AGENT FOR FRA(X)(Q27) EXPRESSION IN LYMPHOCYTES, FIBROBLASTS, AND AMNIOCYTES	23	49
185	8	29	240 1985 AMERICAN JOURNAL OF HUMAN GENETICS 37(3):463-472 MULLIGAN LM; PHILLIPS MA; FORSTERGIBSON CJ; BECKETT J; PARTINGTON MW; SIMPSON NE; HOLDEN JJA; WHITE BN GENETIC-MAPPING OF DNA SEGMENTS RELATIVE TO THE LOCUS FOR THE FRAGILE-X SYNDROME AT XQ27.3	6	49
186	2	17	286 1985 HUMAN GENETICS 69(4):327-331 MATTEI MG; BAETEMAN MA; HEILIG R; OBERLE I; DAVIES K; MANDEL JL; MATTEI JF LOCALIZATION BY INSITU HYBRIDIZATION OF THE COAGULATION FACTOR-IX GENE AND OF 2 POLYMORPHIC DNA PROBES WITH RESPECT TO THE FRAGILE-X SITE	8	49
187	17	40	287 1985 HUMAN GENETICS 71(1):11-18 BROWN WT; GROSS AC; CHAN CB; JENKINS EC GENETIC-LINKAGE HETEROGENEITY IN THE FRAGILE X-SYNDROME	33	49
188	6	15	351 1986 AMERICAN JOURNAL OF MEDICAL GENETICS 23(1-2):643-664 BROWN WT; GROSS AC; CHAN CB; JENKINS EC DNA LINKAGE STUDIES IN THE FRAGILE-X SYNDROME SUGGEST GENETIC-HETEROGENEITY	36	49
189	12	44	529 1988 AMERICAN JOURNAL OF MEDICAL GENETICS 30(1-2):377-392 HAGERMAN RJ; MURPHY MA; WITTENBERGER MD A CONTROLLED TRIAL OF STIMULANT MEDICATION IN CHILDREN WITH THE FRAGILE-X SYNDROME	23	49
190	17	32	582 1988 HUMAN GENETICS 78(3):201-205 BROWN WT; GROSS A; CHAN C; JENKINS EC; MANDEL JL; OBERLE I; ARVEILER B; NOVELLI G; THIBODEAU S; HAGERMAN R; SUMMERS K; TURNER G; WHITE BN; MULLIGAN L; FORSTERGIBSON C; HOLDEN JJA; ZOLL B; KRAWCZAK M; GOONEWARDENA P; GUSTAVSON KH; PETTERSSON U; HOLMGREN G; SCHWARTZ C; HOWARDPEEBLES PN; MURPHY P; BREG WR; VEENEMA H; CARPENTER NJ MULTILOCUS ANALYSIS OF THE FRAGILE-X SYNDROME	33	49
#	LCR	NCR	Nodes / Date / Journal / Authors	LCS	GCS
191	15	24	1381 1995 NATURE GENETICS 10(4):483-485 LUGENBEEL KA; PEIER AM; CARSON NL; CHUDLEY AE; NELSON DL INTRAGENIC LOSS OF FUNCTION MUTATIONS DEMONSTRATE THE PRIMARY ROLE OF FMR1 IN FRAGILE-X SYNDROME	30	49
192	10	36	2055 2001 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98(13):7101-7106 Greenough WT; Klintsova AY; Irwin SA; Galvez R; Bates KE; Weiler IJ Synaptic regulation of protein synthesis and the fragile X protein	30	49
193	7	17	733 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(1):108-116 ROUSSEAU F; VINCENT A; RIVELLA S; HEITZ D; TRIBOLI C; MAESTRINI E; WARREN ST; SUTHERS GK; GOODFELLOW P; MANDEL JL; TONIOLO D; OBERLE I 4 CHROMOSOMAL BREAKPOINTS AND 4 NEW PROBES MARK OUT A 10-CM REGION ENCOMPASSING THE FRAGILE-X LOCUS (FRAXA)	25	48
194	9	31	1089 1993 EUROPEAN JOURNAL OF HUMAN GENETICS 1(1):72-79 DEVRIES BBA; WIEGERS AM; DEGRAAFF E; VERKERK AJMH; VANHEMEL JO; HALLEY DJJ; FRYNS JP; CURFS LMG; NIERMEIJER MF; OOSTRA BA MENTAL STATUS AND FRAGILE-X EXPRESSION IN RELATION TO FMR-1 GENE MUTATION	36	48
195	25	50	1108 1993 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 34(5):673-688 BAILEY A; BOLTON P; BUTLER L; LECOUTEUR A; MURPHY M; SCOTT S; WEBB T; RUTTER M PREVALENCE OF THE FRAGILE-X ANOMALY AMONGST AUTISTIC TWINS AND SINGLETONS	10	48
196	5	27	1505 1996 NUCLEIC ACIDS RESEARCH 24(4):784-792 Mariappan SVS; Catasti P; Chen X; Ratliff R; Moyzis RK; Bradbury EM; Gupta G Solution structures of the individual single strands of the fragile X DNA triplets (GCC)(n)center dot(GGC)(n)	10	48
197	2	28	244 1985 AMERICAN JOURNAL OF HUMAN GENETICS 37(6):1192-1205 NUSSBAUM RL; WALMSLEY RM; LESKO JG; AIRHART SD; LEDBETTER DH THYMIDYLATE SYNTHASE-DEFICIENT CHINESE-HAMSTER CELLS - A SELECTION SYSTEM FOR HUMAN-CHROMOSOME 18 AND EXPERIMENTAL SYSTEM FOR THE STUDY OF THYMIDYLATE SYNTHASE REGULATION AND FRAGILE-X EXPRESSION	6	47
198	2	33	647 1989 JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES 30(6):845-856 COHEN IL; VIETZE PM; SUDHALTER V; JENKINS EC; BROWN WT PARENT CHILD DYADIC GAZE PATTERNS IN FRAGILE-X MALES AND IN NON-FRAGILE-X MALES WITH AUTISTIC DISORDER	30	47
199	16	33	735 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(3):460-467 SUTHERS GK; MULLEY JC; VOELCKEL MA; DAHL N; VAISANEN ML; STEINBACH P; GLASS IA; SCHWARTZ CE; VANOOST BA; THIBODEAU SN; HAITES NE; OOSTRA BA; GINE R; CARBALLO M; MORRIS CP; HOPWOOD JJ; SUTHERLAND GR GENETIC-MAPPING OF NEW DNA PROBES AT XQ27 DEFINES A STRATEGY FOR DNA STUDIES IN THE FRAGILE-X SYNDROME	30	47
200	15	46	1361 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(48):28970-28977 NADEL Y; WEISMANSHOMER P; FRY M THE FRAGILE-X SYNDROME SINGLE-STRAND D(CGG)(N) NUCLEOTIDE REPEATS READILY FOLD BACK TO FORM UNIMOLECULAR HAIRPIN STRUCTURES	11	47

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