#	Cited nodes	Nodes / Authors	GCS	LCS
4101	4	10392 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(4):1418-1422 Brown DW; Yu JH; Kelkar HS; Fernandes M; Nesbitt TC; Keller NP; Adams TH; Leonard TJ Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans	118	6
4102	6	10405 1996 RESEARCH COMMUNICATIONS IN MOLECULAR PATHOLOGY AND PHARMACOLOGY 91(2):149-159 Carcillo JA; Parise RA; Adedoyin A; Frye R; Branch RA; Romkes M CYP2D6 mRNA expression in circulating peripheral blood mononuclear cells correlates with in vivo debrisoquine hydroxylase activity in extensive metabolizers	15	6
4103	7	10462 1997 AMERICAN JOURNAL OF HUMAN GENETICS 60(2):265-271 Nebert DW Polymorphisms in drug-metabolizing enzymes: What is their clinical relevance and why do they exist?	93	6
4104	9	10503 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 343(1):101-108 Huang ZQ; Fasco MJ; Kaminsky LS Alternative splicing of CYP2D mRNA in human breast tissue	11	6
4105	11	10534 1997 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 236(2):306-312 Celander M; Stegeman JJ Isolation of a cytochrome P450 3A cDNA sequence (CYP3A30) from the marine teleost Fundulus heteroclitus and phylogenetic analyses of CYP3A genes	8	6
4106	18	10552 1997 BIOCHEMICAL PHARMACOLOGY 53(7):1029-1040 White RD; Shea D; Solow AR; Stegeman JJ Induction and post-transcriptional suppression of hepatic cytochrome P450 1A1 by 3,3',4,4'-tetrachlorobiphenyl	25	6
4107	12	10698 1997 EUROPEAN JOURNAL OF BIOCHEMISTRY 249(1):270-279 Banci L; Bertini I; Ferroni F; Rosato A Solution structure of reduced microsomal rat cytochrome b(5)	29	6
4108	1	10702 1997 FASEB JOURNAL 11(1):3-14 Weinshilboum RM; Otterness DM; Aksoy IA; Wood TC; Her C; Raftogianis RB Sulfotransferase molecular biology: cDNAs and genes	174	6
4109	13	10795 1997 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 283(3):1168-1176 Zhao XJ; Ishizaki T The in vitro hepatic metabolism of quinine in mice, rats and dogs: Comparison with human liver microsomes	16	6
4110	7	10845 1997 NATURE STRUCTURAL BIOLOGY 4(1):32-35 Curnow KM; Mulatero P; EmericBlanchouin N; AupetitFaisant B; Corvol P; Pascoe L The amino acid substitutions Ser288Gly and Val320Ala convert the cortisol producing enzyme, CYP11B1, into an aldosterone producing enzyme	33	6
4111	5	10883 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(26):14954-14959 Koopmann E; Hahlbrock K Differentially regulated NADPH : cytochrome P450 oxidoreductases in parsley	9	6
4112	3	10938 1998 ACCOUNTS OF CHEMICAL RESEARCH 31(6):363-369 Rusling JF Enzyme bioelectrochemistry in cast biomembrane-like films	87	6
4113	5	10994 1998 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 37(1):57-63 Korytko PJ; Scott JG CYP6D1 protects thoracic ganglia of houseflies from the neurotoxic insecticide cypermethrin	15	6
4114	10	11005 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 243(3):688-693 Benveniste I; Tijet N; Adas F; Philipps G; Salaun JP; Durst F CYP86A1 from Arabidopsis thaliana encodes a cytochrome P450- dependent fatty acid omega-hydroxylase	19	6
4115	14	11014 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 249(1):187-190 Snyder MJ Cytochrome P450 enzymes belonging to the CYP4 family from marine invertebrates	8	6
4116	4	11017 1998 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 251(2):657-661 Dey A; Nebert DW Markedly increased constitutive CYP1A1 mRNA levels in the fertilized ovum of the mouse	18	6
4117	22	11040 1998 BIOCHEMISTRY 37(7):1839-1847 Dierks EA; Davis SC; de Montellano PRO Glu-320 and Asp-323 are determinants of the CYP4A1 hydroxylation regiospecificity and resistance to inactivation by 1-aminobenzotriazole	26	6
4118	37	11046 1998 BIOCHEMISTRY 37(33):11412-11424 Perret A; Pompon D Electron shuttle between membrane-bound cytochrome P450 3A4 and b(5) rules uncoupling mechanisms	20	6
4119	17	11147 1998 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 121(1-3):351-360 Brown DJ; Clark GC; Van Beneden RJ A new cytochrome P450 (CYP30) family identified in the clam, Mercenaria mercenaria	8	6
4120	8	11223 1998 FEBS LETTERS 431(3):343-346 Lamb SB; Lamb DC; Kelly SL; Stuckey DC Cytochrome P450 immobilisation as a route to bioremediation/biocatalysis	14	6
4121	14	11230 1998 FUNDAMENTAL & CLINICAL PHARMACOLOGY 12(5):553-558 Lucas D; Farez C; Bardou LG; Vaisse J; Attali JR; Valensi P Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation	25	6
4122	25	11305 1998 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 286(2):772-779 Pascual JMS; McKenzie A; Yankaskas JR; Falck JR; Zeldin DC Epoxygenase metabolites of arachidonic acid affect electrophysiologic properties of rat tracheal epithelial cells	6	6
4123	25	11334 1998 MOLECULAR PHARMACOLOGY 54(3):504-513 Qu W; Rippe RA; Ma JX; Scarborough P; Biagini C; Fiedorek FT; Travlos GS; Parker C; Zeldin DC Nutritional status modulates rat liver cytochrome P450 arachidonic acid metabolism	9	6
4124	2	11345 1998 NEUROLOGY 50(4):1055-1060 Taivassalo T; De Stefano N; Argov Z; Matthews PM; Chen J; Genge A; Karpati G; Arnold DL Effects of aerobic training in patients with mitochondrial myopathies	28	6
4125	23	11382 1998 PLANT MOLECULAR BIOLOGY 37(1):39-52 Mizutani M; Ward E; Ohta D Cytochrome p450 superfamily in Arabidopsis thaliana: isolation of cDNAs, differential expression, and RFLP mapping of multiple cytochromes p450	23	6
4126	8	11399 1998 STROKE 29(1):229-234 Harder DR; Alkayed NJ; Lange AR; Gebremedhin D; Roman RJ Functional hyperemia in the brain - Hypothesis for astrocyte- derived vasodilator metabolites	34	6
4127	2	11402 1998 TETRAHEDRON-ASYMMETRY 9(16):2833-2844 Schneider S; Wubbolts MG; Sanglard D; Witholt B Production of chiral hydroxy long chain fatty acids by whole cell biocatalysis of pentadecanoic acid with an E-coli recombinant containing cytochrome P450(BM-3) monooxygenase	8	6
4128	24	11412 1998 TOXICOLOGY AND APPLIED PHARMACOLOGY 150(1):106-116 Gilday D; Bellward GD; Sanderson JT; Janz DM; Rifkind AB 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induces hepatic cytochrome P450-dependent arachidonic acid epoxygenation in diverse avian orders: Regioisomer selectivity and immunochemical comparison of the TCDD-induced P450s to CYP1A4 and 1A5	12	6
4129	11	11504 1999 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 259(2):305-310 Winter J; Bilbe G; Richener H; Sehringer B; Kayser H Cloning of a cDNA encoding a novel cytochrome P450 from the insect Locusta migratoria: CYP6H1, a putative ecdysone 20- hydroxylase	16	6
4130	16	11534 1999 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1441(2-3):141-149 Li HY; Poulos TL Fatty acid metabolism, conformational change, and electron transfer in cytochrome P-450(BM-3)	10	6
4131	12	11663 1999 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 51(4-5):412-417 Raunio H; Hakkola J; Hukkanen J; Lassila A; Paivarinta K; Pelkonen O; Anttila S; Piipari R; Boobis A; Edwards RJ Expression of xenobiotic-metabolizing CYPs in human pulmonary tissue	19	6
4132	45	11689 1999 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 29(9):757-777 Scott JG Cytochromes P450 and insecticide resistance	30	6
4133	25	11733 1999 JOURNAL OF CLINICAL INVESTIGATION 104(6):751-760 Holla VR; Makita K; Zaphiropoulos PG; Capdevila JH The kidney cytochrome P-4502C23 arachidonic acid epoxygenase is upregulated during dietary salt loading	21	6
4134	24	11756 1999 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 289(3):1611-1619 Mastyugin V; Aversa E; Bonazzi A; Vafaes C; Mieyal P; Schwartzman ML Hypoxia-induced production of 12-hydroxyeicosanoids in the corneal epithelium: Involvement of a cytochrome P-4504B1 isoform	12	6
4135	13	11798 1999 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 439(2):287-300 Kranendonk M; Fisher CW; Roda R; Carreira F; Theisen P; Laires A; Rueff J; Vermeulen NPE; Estabrook RW Escherichia coli MTC, a NADPH cytochrome P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450: Comparison of three types of expression systems	6	6
4136	9	11839 1999 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96(4):1750-1755 Siminszky B; Corbin FT; Ward ER; Fleischmann TJ; Dewey RE Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco enhances the metabolism of phenylurea herbicides	19	6
4137	9	11903 2000 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 40():581-616 Tukey RH; Strassburg CP Human UDP-glucuronosyltransferases: Metabolism, expression, and disease	111	6
4138	29	11911 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 374(2):269-278 Roussel F; Khan KK; Halpert JR The importance of SRS-1 residues in catalytic specificity of human cytochrome p450 3A4	20	6
4139	28	12051 2000 DRUG METABOLISM REVIEWS 32(3-4):339-361 Wrighton SA; Schuetz EG; Thummel KE; Shen DD; Korzekwa KR; Watkins PB The human CYP3A subfamily: Practical considerations	24	6
4140	19	12128 2000 JOURNAL OF BIOTECHNOLOGY 84(3):249-257 Schwaneberg U; Appel D; Schmitt J; Schmid RD P450 in biotechnology: zinc driven omega-hydroxylation of p- nitrophenoxydodecanoic acid using P450BM-3 F87A as a catalyst	11	6
4141	9	12228 2000 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(20):10769-10774 Handschin C; Podvinec M; Meyer UA CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)	22	6
4142	30	12291 2001 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 280(1):H1-H10 Jacobs ER; Zeldin DC The lung HETEs (and EETs) up	13	6
4143	13	12343 2001 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 280(3):892-897 Bylund J; Bylund M; Oliw EH cDNA cloning and expression of CYP4F12, a novel human cytochrome P450	12	6
4144	11	12369 2001 BIOCHEMISTRY 40(45):13421-13429 Ost TWB; Miles CS; Munro AW; Murdoch J; Reid GA; Chapman SK Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450BM3	7	6
4145	40	12523 2001 JOURNAL OF BIOLOGICAL CHEMISTRY 276(33):30885-30891 Yamazaki H; Shimada T; Martin MV; Guengerich FP Stimulation of cytochrome P450 reactions by apo-cytochrome b(5) - Evidence against transfer of heme from cytochrome P450 3A4 to apo-cytochrome b5, or heme oxygenase	9	6
4146	1	29 1958 BIOCHEMICAL JOURNAL 70():381-390 BENDALL DS CYTOCHROMES AND SOME RESPIRATORY ENZYMES IN MITOCHONDRIA FROM THE SPADIX OF ARUM-MACULATUM	39	5
4147	3	56 1959 CANCER RESEARCH 19(9):927-& MONIER R; ZAJDELA F; CHAIX P; PETIT JF LOW-TEMPERATURE SPECTROGRAPHIC STUDY OF THE CYTOCHROMES IN VARIOUS RAT AND MOUSE TUMORS	35	5
4148	4	66 1959 JOURNAL OF BIOLOGICAL CHEMISTRY 234(8):2176-2186 HUNTER FE; LEVY JF; FINK J; SCHUTZ B; GUERRA F; HURWITZ A STUDIES ON THE MECHANISM BY WHICH ANAEROBIOSIS PREVENTS SWELLING OF MITOCHONDRIA INVITRO - EFFECT OF ELECTRON TRANSPORT CHAIN INHIBITORS	133	5
4149	1	70 1959 JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY 53(1):93-117 LINDENMAYER A OXIDATIVE METABOLISM AND ABSORPTION SPECTRA OF ANAEROBICALLY GROWN YEAST - MANOMETRIC DATA AND ABSOLUTE ABSORPTION SPECTRA	19	5
4150	3	82 1960 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 3(4):423-427 MINAKAMI S; RINGLER RL; SINGER TP ASSAY OF THE DPNH DEHYDROGENASE OF THE RESPIRATORY CHAIN IN PARTICULATE AND SOLUBLE PREPARATIONS	15	5
4151	5	97 1960 CANCER RESEARCH 20(9):1408-1412 SACKTOR B; DICK AR ALPHA-GLYCEROPHOSPHATE AND LACTIC DEHYDROGENASES OF HEMATOPOIETIC CELLS FROM LEUKEMIC MICE	27	5
4152	4	124 1961 BIOCHEMICAL JOURNAL 80(3):623-& BIRT LM FLIGHT-MUSCLE MITOCHONDRIA OF LUCILIA CUPRINA AND MUSCA DOMESTICA - ESTIMATION OF PYRIDINE NUCLEOTIDE CONTENT AND OF RESPONSE OF RESPIRATION TO ADENOSINE DIPHOSPHATE	22	5
4153	4	163 1962 BIOCHEMISTRY 1(2):281-& JOEL CD; BALL EG ELECTRON TRANSMITTER SYSTEM OF BROWN ADIPOSE TISSUE	37	5
4154	3	178 1962 JOURNAL OF BIOCHEMISTRY 51(3):204-& ORII Y; SEKUZU I; OKUNUKI K STUDIES ON CYTOCHROME C1 .2. OXIDATION MECHANISM OF CYTOCHROME C1 IN PRESENCE OF CYTOCHROMES A AND C1	60	5
4155	3	179 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(4):1332-& WHITE DC; SMITH L HEMATIN ENZYMES OF HEMOPHILUS PARAINFLUENZAE	47	5
4156	1	214 1963 BIOCHIMICA ET BIOPHYSICA ACTA 73(2):311-& HEMKER HC CONTRIBUTION OF VARIOUS PHOSPHORYLATING STEPS IN RESPIRATORY CHAIN TO DINITROPHENOL-INDUCED ATPASE OF RAT-LIVER MITOCHONDRIA	38	5
4157	1	280 1964 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 14(1):79-& WU R CONTROL OF GLYCOLYSIS BY PHOSPHOFRUCTOKINASE IN SLICES OF RAT LIVER NOVIKOFF HEPATOMA + ADENOCARCINOMAS	49	5
4158	3	282 1964 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 17(1):62-& EPEL D PRIMARY METABOLIC CHANGE OF FERTILIZATION - INTERCONVERSION OF PYRIDINE NUCLEOTIDES	78	5
4159	2	291 1964 BIOCHEMISTRY 3(6):812-& WALTER P; LARDY HA EFFECT OF ANTIMYCIN A ON OXIDATIVE PHOSPHORYLATION WITH FERRICYANIDE AS ELECTRON ACCEPTOR	14	5
4160	1	302 1964 BIOCHIMICA ET BIOPHYSICA ACTA 89(2):385-& TERWELLE HF; SLATER EC UNCOUPLING OF RESPIRATORY-CHAIN PHOSPHORYLATION BY ARSENATE + EVIDENCE FOR EXISTENCE OF STABLE X-P INTERMEDIATE OF OXIDATIVE PHOSPHORYLATION	33	5
4161	1	309 1964 BIOCHIMICA ET BIOPHYSICA ACTA 93(3):462-& BRUNI A; AZZONE GF SITES OF ACTION OF ATRACTYLOSIDE + OLIGOMYCIN IN MITOCHONDRIAL ENERGY-TRANSFER SYSTEM	30	5
4162	1	319 1964 JOURNAL OF BIOLOGICAL CHEMISTRY 239(6):2022-& RAJAGOPALAN KV; HANDLER P HEPATIC ALDEHYDE OXIDASE .2. DIFFERENTIAL INHIBITION OF ELECTRON TRANSFER TO VARIOUS ELECTRON ACCEPTORS	96	5
4163	2	377 1965 BIOCHIMICA ET BIOPHYSICA ACTA 94(2):504-& INFANTE AA; KLAUPIKS D; DAVIES RE PHOSPHORYLCREATINE CONSUMPTION DURING SINGLE-WORKING CONTRACTIONS OF ISOLATED MUSCLE	29	5
4164	4	392 1965 BIOCHIMICA ET BIOPHYSICA ACTA 105(2):205-& HOWLAND JL INHIBITION OF MITOCHONDRIAL SUCCINATE OXIDATION BY ALKYL HYDROXY NAPHTHOQUINONES	22	5
4165	4	485 1966 BIOCHEMISTRY 5(7):2416-& REPORTER M INTERACTION OF ANTIMYCIN A WITH BIOLOGICAL SYSTEMS	18	5
4166	3	494 1966 BIOCHIMICA ET BIOPHYSICA ACTA 122(2):157-& JENSEN PK ANTIMYCIN-INSENSITIVE OXIDATION OF SUCCINATE AND REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE IN ELECTRON-TRANSPORT PARTICLES .I. PH DEPENDENCY AND HYDROGEN PEROXIDE FORMATION	19	5
4167	1	506 1966 ENDOCRINOLOGY 78(3):661-& MALOOF F; SOODAK M CHARACTERIZATION OF 2 HEME PROTEINS IN CALF THYROID MICROSOMES	11	5
4168	4	562 1966 PHYSIOLOGIA PLANTARUM 19(4):1049-& BETZ A METABOLIC FLUX IN YEAST CELLS WITH OSCILLATORY CONTROLLED GLYCOLYSIS	20	5
4169	2	611 1967 BIOCHEMICAL JOURNAL 103(1):P13-& MCLEAN AEM EFFECT OF HALOGENATED HYDROCARBONS ON MICROSOMAL CYTOCHROME (P- 450)	7	5
4170	1	638 1967 BIOCHIMICA ET BIOPHYSICA ACTA 131(1):14-& PAPA S; TAGER JM; FRANCAVI.A; DEHAAN EJ; QUAGLIAR.E CONTROL OF GLUTAMATE DEHYDROGENASE ACTIVITY DURING GLUTAMATE OXIDATION IN ISOLATED RAT-LIVER MITOCHONDRIA	59	5
4171	3	646 1967 BIOCHIMICA ET BIOPHYSICA ACTA 143(1):1-& TERWELLE HF; SLATER EC UNCOUPLING OF RESPIRATORY-CHAIN PHOSPHORYLATION BY ARSENATE	67	5
4172	5	651 1967 BIOCHIMICA ET BIOPHYSICA ACTA 143(3):487-& GILMOUR MV; WILSON DF; LEMBERG R LOW-TEMPERATURE SPECTRAL PROPERTIES OF MAMMALIAN CYTOCHROME OXIDASE .2. ENZYME ISOLATED FROM BEEF-HEART MITOCHONDRIA	38	5
4173	8	652 1967 BIOCHIMICA ET BIOPHYSICA ACTA 143(3):532-& PERON FG; CALDWELL BV STEROID HYDROXYLATIONS BY GUINEA-PIG ADRENAL TISSUE FRACTIONS	10	5
4174	7	662 1967 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY 23(1):277-& CHEAH KS OXIDASE SYSTEMS OF MONIEZIA EXPANSA (CESTODA)	49	5
4175	6	684 1967 JOURNAL OF BIOCHEMISTRY 62(4):447-& SUZUKI M; IMAI K; ITO A; OMURA T; SATO R EFFECTS OF THYROIDECTOMY AND TRIIODOTHYRONINE ADMINISTRATION ON OXIDATIVE ENZYMES IN RAT LIVER MICROSOMES	26	5
4176	6	738 1968 ADVANCES IN CHEMISTRY SERIES (77):220-& COOPER DY; NARASIMH.S; ROSENTHA.O; ESTABROOK RW ROLE OF CYTOCHROME P-450 IN MIXED-FUNCTION OXIDATIONS	5	5
4177	3	779 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 31(6):925-& YOUNG DG; HALL PF COFACTOR REQUIREMENTS FOR CONVERSION OF CHOLESTEROL SULFATE TO PREGNENOLONE SULFATE BY A SUBMITOCHONDRIAL SYSTEM FROM BOVINE ADRENAL CORTEX	12	5
4178	7	802 1968 BIOCHIMICA ET BIOPHYSICA ACTA 153(2):317-& KANIUGA Z; GARDAS A; JAKUBIAK M STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE- ADENINE DINUCLEOTIDE DEHDYROGENASE .I. EFFECT OF DIETHYL ETHER ON PARTICULATE NADH DEHYDROGENASE	7	5
4179	5	813 1968 BIOCHIMICA ET BIOPHYSICA ACTA 162(4):624-& HONJO I; OZAWA K LYSOLECITHIN INHIBITION OF MITOCHONDRIAL METABOLISM	32	5
4180	4	866 1968 JOURNAL OF BIOCHEMISTRY 63(2):207-& IMAI K; ASANO A; SATO R OXIDATIVE PHOSPHORYLATION IN MICROCOCCUS DENITRIFICANS .4. FURTHER CHARACTERIZATION OF ELECTRON-TRANSFER PATHWAY AND PHOSPHORYLATION ACTIVITY IN NADH OXIDATION	28	5
4181	5	968 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 131(2):441-& GALLANT S; BROWNIE AC CORTICOSTEROIDOGENESIS AND CYTOCHROME LEVELS IN REGENERATING RAT ADRENAL	10	5
4182	5	984 1969 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 36(4):526-& BARON J; TEPHLY TR ROLE OF HEME SYNTHESIS DURING INDUCTION OF HEPATIC MICROSOMAL CYTOCHROME P-450 AND DRUG METABOLISM PRODUCED BY BENZPYRENE	36	5
4183	4	1086 1969 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 350(1):69-& MARKS F; HECKER E METABOLISM AND MECHANISM OF ACTION OF OESTROGENS .11. METABOLISM OF [4-14C]2-HYDROXY-OESTRONE IN RAT-LIVER MICROSOMES	38	5
4184	5	1102 1969 JOURNAL OF BIOCHEMISTRY 65(4):597-& ICHII S; YAGO N HORMONAL REGULATION OF AMINOPYRINE N-DEMETHYLASE SYSTEM IN RAT LIVER	13	5
4185	4	1113 1969 JOURNAL OF BIOLOGICAL CHEMISTRY 244(9):2358-& HATEFI Y; STEMPEL KE; HANSTEIN WG INHIBITORS AND ACTIVATORS OF MITOCHONDRIAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE	39	5
4186	1	1124 1969 JOURNAL OF CELL BIOLOGY 43(2P1):207-& KLEVECZ RR TEMPORAL ORDER IN MAMMALIAN CELLS .I. PERIODIC SYNTHESIS OF LACTATE DEHYDROGENASE IN CELL CYCLE	56	5
4187	1	1129 1969 JOURNAL OF MEDICINAL CHEMISTRY 12(2):207-& MCMAHON RE; MILLS J; CULP HW; GIBSON WR; MILLER WM; MARSHALL FJ DEMETHYLATION STUDIES .6. INHIBITION OF HEPATIC MICROSOMAL OXYGENATION BY 2,4-DICHLORO(6-PHENYLPHENOXY)ETHYLAMINE AND RELATED COMPOUNDS	32	5
4188	6	1172 1969 SCIENCE 165(3900):1371-& SHOEMAN DW; WHITE JG; MANNERIN.GJ CYTOCHROME P-420 - TUBULAR AGGREGATES FROM HEPATIC MICROSOMES	19	5
4189	4	1182 1970 ADVANCES IN ENZYMOLOGY AND RELATED SUBJECTS OF BIOCHEMISTRY 33():119-& BUCHANAN BB; ARNON DI FERREDOXINS - CHEMISTRY AND FUNCTION IN PHOTOSYNTHESIS, NITROGEN FIXATION, AND FERMENTATIVE METABOLISM	120	5
4190	3	1196 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 137(2):357-& KIMURA T; HUANG JJ STUDIES ON ADRENAL STEROID HYDROXYLASES - OPTICAL ABSORPTION SPECTROSCOPY OF ADRENAL IRON-SULFUR PROTEIN (ADRENODOXIN) AND ITS APOPROTEIN	12	5
4191	5	1198 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 138(2):632-& COLBY HD IN VIVO INTERACTION OF METYRAPONE WITH ADRENAL CORTICAL MITOCHONDRIAL CYTOCHROME-P-450	5	5
4192	9	1255 1970 BIOCHEMISTRY 9(19):3653-& KLEIN KO; HARDING BW ELECTRON TRANSPORT REVERSAL AND STEROID 11BETA-HYDROXYLATION IN ADRENAL CORTICAL MITOCHONDRIA	8	5
4193	4	1292 1970 ENDOCRINOLOGY 86(5):1093-& COLBY HD; SKELTON FR; BROWNIE AC TESTOSTERONE-INDUCED HYPERTENSION IN RAT	48	5
4194	11	1318 1970 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 351(12):1475-& UEHLEKE H; SCHNITGE.F; HELLMER KH DIFFERENT MICROSOMAL DRUG OXIDATIONS AFTER INACTIVATION OF CYTOCHROME P-450 BY UV-IRRADIATION OR BY DEOXYCHOLATE PRETREATMENT	21	5
4195	5	1354 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(16):4187-& HILTON J; SARTOREL.AC INDUCTION BY PHENOBARBITAL OF MICROSOMAL MIXED OXIDASE ENZYMES IN REGENERATING RAT LIVER	62	5
4196	22	1375 1970 JOURNAL OF THEORETICAL BIOLOGY 28(2):233-& STOREY BT CHEMICAL HYPOTHESIS FOR ENERGY CONSERVATION IN MITOCHONDRIAL RESPIRATORY CHAIN	16	5
4197	9	1392 1970 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 266(1):61-& KAHL GF EXPERIMENTS ON METYRAPONE REDUCING MICROSOMAL ENZYME SYSTEM	36	5
4198	2	1409 1970 REVUE CANADIENNE DE BIOLOGIE 29(4):377-& FOUTS JR SOME EFFECTS OF INSECTICIDES ON HEPATIC MICROSOMAL ENZYMES IN VARIOUS ANIMAL SPECIES	19	5
4199	2	1425 1971 ANALYTICAL BIOCHEMISTRY 42(1):195-& MORRISON M; BAYSE GS; MICHAELS AW DETERMINATION OF SPECTRAL PROPERTIES OF AQUEOUS I2 AND I3- AND EQUILIBRIUM CONSTANT	15	5
4200	6	1645 1971 JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 2(2):111-& SAFER B; SMITH CM; WILLIAMS.JR CONTROL OF TRANSPORT OF REDUCING EQUIVALENTS ACROSS MITOCHONDRIAL MEMBRANE IN PERFUSED RAT HEART	85	5

#	Cited nodes	Nodes / Authors	GCS	LCS
4201	5	1666 1971 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 10(16):901-& LEWIS AM; BRYAN GT CYTOCHROME P450 AND STEROID 21-HYDROXYLATION IN MICROSOMES FROM HUMAN ADRENAL CORTEX	11	5
4202	3	1680 1971 NATURE-NEW BIOLOGY 231(19):60-& FLINT APF; ARMSTRON.DT INTRACELLULAR LOCALIZATION OF CHOLESTEROL SIDE CHAIN CLEAVAGE ENZYME IN CORPORA LUTEA OF COW AND RAT	18	5
4203	8	1682 1971 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 268(2):242-& UEHLEKE H; HELLMER KH COMPETITIVE INHIBITION OF MICROSOMAL N-HYDROXYLATION OF 4- CHLOROANILINE BY METYRAPONE AND CYCLOHEXANE	9	5
4204	4	1694 1971 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 68(12):3015-& EATON WA; PALMER G; FEE JA; KIMURA T; LOVENBER.W TETRAHEDRAL IRON IN ACTIVITY CENTER OF PLANT FERREDOXINS AND BEEF ADRENODOXIN	72	5
4205	2	1706 1971 YAKUGAKU ZASSHI 91(1):142-& KAMATAKI T; FUKAZAWA H; KITAGAWA H STUDIES ON HEXOBARBITAL DIFFERENCE SPECTRUM WITH MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	5	5
4206	2	1713 1972 ACTA ENDOCRINOLOGICA 71(2):374-& KAPPUS H; BOLT HM; REMMER H DEMETHYLATION OF MESTRANOL TO ETHINYLESTRADIOL IN-VITRO AND IN- VIVO	41	5
4207	4	1777 1972 BIOCHEMICAL GENETICS 7(2):141-& OBRIEN SJ; MACINTYR.RJ ALPHA-GLYCEROPHOSPHATE CYCLE IN DROSOPHILA-MELANOGASTER .1. BIOCHEMICAL AND DEVELOPMENTAL ASPECTS	88	5
4208	4	1792 1972 BIOCHEMICAL PHARMACOLOGY 21(11):1595-& ARCHAKOV AI; ALEXANDR.TA; BOKHONKO AI; PANCHENC.LF; KARUZINA II STUDIES ON LOCALIZATION OF REACTION SITES WITHIN REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE-OXYGENASE SYSTEM OF RAT-LIVER MICROSOMES FOR N-OXIDATION AND C-OXIDATION OF DIMETHYLANILINE AND FOR PEROXIDATION OF UNSATURATED FATTY-ACIDS	10	5
4209	2	1804 1972 BIOCHEMICAL PHARMACOLOGY 21(24):3235-& WILEY RA; SASAME HA; STERNSON LA; GILLETTE JR ENZYMATIC OXIDATION OF DIPHENYLMETHYLPHOSPHINE AND 3- DIMETHYLAMINOPROPYLDIPHENYLPHOSPHINE BY RAT-LIVER MICROSOMES	21	5
4210	13	1809 1972 BIOCHEMISTRY 11(6):955-& ROTH JA; NEAL RA SPECTRAL STUDIES OF BINDING OF O,O-DIETHYL PARA NITROPHENYLPHOSPHOROTHIONATE (PARATHION) TO CYTOCHROME-P-450	7	5
4211	12	1811 1972 BIOCHEMISTRY 11(15):2891-& HALL PF A POSSIBLE ROLE FOR TRANSHYDROGENATION IN SIDE-CHAIN CLEAVAGE OF CHOLESTEROL	21	5
4212	13	1826 1972 BIOCHIMICA ET BIOPHYSICA ACTA 267(1):48-& STOREY BT RESPIRATORY CHAIN OF PLANT MITOCHONDRIA .13. REDOX STATE CHANGES OF CYTOCHROME B562 IN MUNG BEAN SEEDLING MITOCHONDRIA TREATED WITH ANTIMYCIN-A	20	5
4213	5	1837 1972 BIOCHIMICA ET BIOPHYSICA ACTA 275(2):148-& DOUCE R; BONNER WD; CHRISTEN.EL PREPARATION OF INTACT PLANT MITOCHONDRIA	307	5
4214	3	1852 1972 CANCER CHEMOTHERAPY REPORTS PART 1 56(5):603-610 ALLEN LM; CREAVEN PJ IN-VITRO ACTIVATION OF ISOPHOSPHAMIDE (NSC-109724), A NEW OXAZAPHOSPHORINE, BY RAT-LIVER MICROSOMES	59	5
4215	11	1855 1972 CHEMICO-BIOLOGICAL INTERACTIONS 4(6):399-& PHILPOT RM; HODGSON E DIFFERENCES IN CYTOCHROME P-450S FROM RESISTANT AND SUSCEPTIBLE HOUSE-FLIES	15	5
4216	2	1864 1972 CLINICAL PHARMACOLOGY & THERAPEUTICS 13(4):552-& OMALLEY K; STEVENSO.IH; CROOKS J IMPAIRMENT OF HUMAN DRUG METABOLISM BY ORAL CONTRACEPTIVE STEROIDS	118	5
4217	4	1893 1972 FEDERATION PROCEEDINGS 31(1):21-& SCHATZ G; ROUSLIN W; SALTZGAB.J; WHARTON DC; GROOT GSP; MASON T BIOGENESIS OF MITOCHONDRIAL INNER MEMBRANES IN BAKERS-YEAST	88	5
4218	4	1898 1972 GASTROENTEROLOGY 63(5):837-& GREIM H; TRULZSCH D; SCHAFFNE.F; DRESSLER K; CZYGAN P; POPPER H; ROBOZ J; HUTTERER F MECHANISM OF CHOLESTASIS .5. BILE-ACIDS IN NORMAL RAT LIVERS AND IN THOSE AFTER BILE-DUCT LIGATION	170	5
4219	5	1912 1972 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 20(3):553-& SELL JL; POONACHA KB; DAVISON KL DECREASED ANILINE HYDROXYLASE-ACTIVITY IN JAPANESE-QUAIL DUE TO DIETARY DDT	9	5
4220	2	1954 1972 JOURNAL OF NUTRITION 102(7):857-& SIAMI G; SCHULERT AR; NEAL RA POSSIBLE ROLE FOR MIXED FUNCTION OXIDASE ENZYME-SYSTEM IN REQUIREMENT FOR SELENIUM IN RAT	26	5
4221	8	1964 1972 JOURNAL OF STEROID BIOCHEMISTRY 3(6):847-& HAKSAR A; PERON FG POSSIBLE FUNCTION OF PYRUVATE IN STEROIDOGENIC RESPONSE OF RAT ADRENAL CELL SUSPENSIONS TO ACTH, CYCLIC-3',5'-AMP AND DIBUTYRYL CYCLIC-3',5'-AMP	21	5
4222	6	1969 1972 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 11(12):597-& LUCIER GW; KLEIN R; MCDANIEL OS; MATTHEWS HB INCREASED DEGRADATION OF RAT-LIVER CO-BINDING PIGMENT BY METHYLMERCURY HYDROXIDE	16	5
4223	9	2054 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):449-457 COON MJ; VANDERHO.TA; KASCHNIT.RM; STROBEL HW BIOCHEMICAL STUDIES ON CYTOCHROME-P-450 SOLUBILIZED FROM LIVER- MICROSOMES - PARTIAL-PURIFICATION AND MECHANISM OF CATALYSIS	15	5
4224	6	2086 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 54(2):764-769 BARON J STUDIES ON IMMUNOCHEMICAL AND FUNCTIONAL SIMILARITIES AMONG IRON-SULFUR PROTEINS INVOLVED IN MITOCHONDRIAL STEROID HYDROXYLATIONS	5	5
4225	4	2104 1973 BIOCHEMICAL PHARMACOLOGY 22(12):1463-1476 MOFFITT AE; MURPHY SD EFFECT OF EXCESS AND DEFICIENT COPPER INTAKE ON RAT-LIVER MICROSOMAL ENZYME-ACTIVITY	43	5
4226	3	2116 1973 BIOCHEMICAL PHARMACOLOGY 22(23):2989-2996 SCHMIDT HL; MOLLER MR; WEBER N SUBSTITUENT EFFECTS ON MICROSOMAL DEALKYLATION OF AROMATIC N- ALKYL, O-ALKYL AND S-ALKYL COMPOUNDS	14	5
4227	2	2161 1973 BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY 9(1):4-9 RAO HRG; ANDERS MW INHIBITION OF MICROSOMAL DRUG-METABOLISM BY ANTICHOLINESTERASE INSECTICIDES	13	5
4228	18	2174 1973 CHEMICO-BIOLOGICAL INTERACTIONS 7(4):205-222 HOOK GER; BEND JR; FOUTS JR EFFECT OF SOME BIPHENYL SOLUBILIZING AND SUSPENDING AGENTS ON BIPHENYL 4-HYDROXYLASE OF RABBIT LIVER-MICROSOMES	13	5
4229	12	2204 1973 DRUG METABOLISM AND DISPOSITION 1(1):216-223 STRIPP B; MENARD RH; ZAMPAGLI.NG; HAMRICK ME; GILLETTE JR EFFECT OF STEROIDS ON DRUG-METABOLISM IN MALE AND FEMALE RATS	34	5
4230	1	2239 1973 FEBS LETTERS 35(1):86-90 DEBEY P; BALNY C; DOUZOU P LOW-TEMPERATURE STUDIES OF MICROSOMAL CYTOCHROME P450 FLASH- PHOTOLYSIS EXPERIMENTS .2.	18	5
4231	10	2316 1973 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 186(3):441-446 RUMACK BH; HOLTZMAN J; CHASE HP HEPATIC DRUG-METABOLISM AND PROTEIN MALNUTRITION	27	5
4232	2	2336 1973 NATURE-NEW BIOLOGY 241(110):163-166 FRASER DR; KODICEK E REGULATION OF 25-HYDROXYCHOLECALCIFEROL-1-HYDROXYLASE ACTIVITY IN KIDNEY BY PARATHYROID-HORMONE	447	5
4233	4	2352 1973 RADIATION RESEARCH 53(1):65-76 KNOTT JCA; WILLS ED EFFECTS OF WHOLE-BODY IRRADIATION AND HORMONES ON DRUG- METABOLISM IN LIVER ENDOPLASMIC-RETICULUM	22	5
4234	4	2354 1973 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 5(2):319-332 ROSS WE; SIMRELL C; OPPELT WW SEX-DEPENDENT EFFECTS OF CYCLIC-AMP ON HEPATIC MIXED-FUNCTION OXIDASE SYSTEM	19	5
4235	6	2446 1974 BIOCHEMICAL PHARMACOLOGY 23(22):3191-3197 JONSSON JA HYDROXYLATION OF AMPHETAMINE TO PARAHYDROXYAMPHETAMINE BY RAT- LIVER MICROSOMES	35	5
4236	4	2447 1974 BIOCHEMICAL PHARMACOLOGY 23(23):3309-3315 ULLRICH V; WEBER P DIRECT TEST FOR MONO-OXYGENASE ACTIVITY OF INTACT SMALL- INTESTINE USING SURFACE REFLECTANCE FLUORIMETRY	7	5
4237	8	2478 1974 CHEMICO-BIOLOGICAL INTERACTIONS 8(1):11-18 KRAMER A; STAUDING.H; ULLRICH V EFFECT OF N-HEXANE INHALATION ON MONOOXYGENASE SYSTEM IN MICE LIVER-MICROSOMES	39	5
4238	4	2625 1974 TOXICOLOGY AND APPLIED PHARMACOLOGY 28(2):216-226 ILETT KF; STRIPP B; MENARD RH; REID WD; GILLETTE JR STUDIES ON MECHANISM OF LUNG TOXICITY OF PARAQUAT - COMPARISON OF TISSUE DISTRIBUTION AND SOME BIOCHEMICAL PARAMETERS IN RATS AND RABBITS	150	5
4239	3	2654 1975 ANNALS OF HUMAN GENETICS 39(OCT):203-212 POVEY S; WILSON DE; HARRIS H; GORMLEY IP; PERRY P; BUCKTON KE SUB-UNIT STRUCTURE OF SOLUBLE AND MITOCHONDRIAL MALIC ENZYME - DEMONSTRATION OF HUMAN MITOCHONDRIAL ENZYME IN HUMAN-MOUSE HYBRIDS	46	5
4240	4	2673 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 170(1):61-72 CROTEAU R; KOLATTUKUDY PE BIOSYNTHESIS OF HYDROXYFATTY ACID POLYMERS - ENZYMATIC EPOXIDATION OF 18-HYDROXYOLEIC ACID TO 18-HYDROXY-CIS-9,10- EPOXYSTEARIC ACID BY A PARTICULATE PREPARATION FROM SPINACH (SPINACIA-OLERACEA)	36	5
4241	2	2714 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(1):175-177 WOLF CR; KING LJ; PARKE DV ANAEROBIC DECHLORINATION OF TRICHLOROFLUOROMETHANE BY LIVER MICROSOMAL PREPARATIONS INVITRO	9	5
4242	9	2730 1975 BIOCHEMISTRY 14(1):89-96 PFEIFFER DR; TCHEN TT ACTIVATION OF ADRENAL-CORTEX MITOCHONDRIAL MALIC ENZYME BY CA2+ AND MG2+	26	5
4243	7	2743 1975 BIOCHIMICA ET BIOPHYSICA ACTA 387(3):461-474 APPLEBY CA; TURNER GL; MACNICOL PK INVOLVEMENT OF OXYLEGHEMOGLOBIN AND CYTOCHROME-P-450 IN AN EFFICIENT OXIDATIVE-PHOSPHORYLATION PATHWAY WHICH SUPPORTS NITROGEN-FIXATION IN RHIZOBIUM	88	5
4244	7	2762 1975 CANCER RESEARCH 35(2):382-389 GURTOO HL; DAVE CV INVITRO METABOLIC CONVERSION OF AFLATOXINS AND BENZO(A)PYRENE TO NUCLEIC ACID-BINDING METABOLITES	89	5
4245	7	2765 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):817-823 ARIYOSHI T; IDEGUCHI K; ISHIZUKA Y; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .1. EFFECTS OF NUMBER OF CHLORINE ATOMS IN CHLORINATED BENZENES ON COMPONENTS OF DRUG-METABOLIZING SYSTEM AND HEPATIC CONSTITUENTS	36	5
4246	8	2766 1975 CHEMICAL & PHARMACEUTICAL BULLETIN 23(4):824-830 ARIYOSHI T; IDEGUCHI K; IWASAKI K; ARAKAKI M RELATIONSHIP BETWEEN CHEMICAL-STRUCTURE AND ACTIVITY .2. INFLUENCES OF ISOMERS IN DICHLOROBENZENE, TRICHLOROBENZENE, AND TETRACHLOROBENZENE ON ACTIVITIES OF DRUG-METABOLIZING-ENZYMES	39	5
4247	7	2784 1975 DRUG METABOLISM AND DISPOSITION 3(2):104-112 KUBIC VL; ANDERS MW METABOLISM OF DIHALOMETHANES TO CARBON-MONOXIDE .2. INVITRO STUDIES	83	5
4248	7	2905 1975 STEROIDS 26(5):571-578 LEE QP; ZACHARIAH PK; JUCHAU MR DIFFERENTIAL INHIBITION OF ANDROST-4-EN-3,17-DIONE AROMATIZATION BY CARBON-MONOXIDE IN PRESENCE OF ESTR-4-EN-3,17- DIONE	8	5
4249	5	2942 1976 ANALYTICAL BIOCHEMISTRY 71(1):265-272 FAN LL; MASTERS BSS; PROUGH RA MICROSOMAL LAURIC ACID 11-HYDROXYLATION AND 12-HYDROXYLATION - NEW ASSAY METHOD UTILIZING HIGH-PRESSURE LIQUID-CHROMATOGRAPHY	20	5
4250	5	2952 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 172(1):123-129 CONDIE LW; BARON J; TEPHLY TR STUDIES ON ADRENAL DELTA-AMINOLEVULINIC-ACID SYNTHETASE	34	5
4251	9	2958 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 173(2):710-719 HOLTZMAN JL; RUMACK BH; ERICKSON RR SPECTROPHOTOMETRIC AND RADIOMETRIC STUDIES ON INVIVO BINDING OF PHENOBARBITAL TO HEPATIC MICROSOMES	13	5
4252	19	2965 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 175(2):443-452 FERRIS JP; MACDONALD LH; PATRIE MA; MARTIN MA ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY IN FUNGUS CUNNINGHAMELLA- BAINIERI - EVIDENCE FOR PRESENCE OF CYTOCHROME-P-450	75	5
4253	3	2993 1976 BIOCHEMICAL PHARMACOLOGY 25(4):477-481 KOUROUNAKIS P; SZABO S; SELYE H EFFECT OF FLUOROSTEROIDS ON DRUG RESPONSE AND METABOLISM	14	5
4254	1	3018 1976 BIOCHIMICA ET BIOPHYSICA ACTA 434(1):244-257 CARDENAS J; MORTENSON LE; YOCH DC PURIFICATION AND PROPERTIES OF PARAMAGNETIC PROTEIN FROM CLOSTRIDIUM-PASTEURIANUM W5	34	5
4255	3	3028 1976 BIOORGANICHESKAYA KHIMIYA 2(4):549-553 AKHREM AA; ABELIOVICH ML; DVORNIKOV SS; USANOV SA; METELITSA DI KINETICS OF NAPHTHALENE HYDROXYLATION BY TERTIARY BUTYL HYDROPEROXIDE IN A SYSTEM WITH RAT-LIVER MICROSOMES AND MOCL5	11	5
4256	4	3039 1976 CANCER TREATMENT REPORTS 60(9):1285-1294 GURTOO HL; GESSNER T; CULLITON P STUDIES OF EFFECTS OF CYCLOPHOSPHAMIDE, VINCRISTINE, AND PREDNISONE ON SOME HEPATIC OXIDATIONS AND CONJUGATIONS	38	5
4257	10	3041 1976 CHEMICO-BIOLOGICAL INTERACTIONS 12(1):1-12 NAGATA C; FUJITA H; IMAMURA A MOLECULAR-ORBITAL STUDY ON INTERACTION BETWEEN CYTOCHROME-P-450 AND ITS SUBSTRATES	12	5
4258	12	3043 1976 CHEMICO-BIOLOGICAL INTERACTIONS 13(2):127-140 ARGUS MF; ARCOS JC; PASTOR KM; WU BC; VENKATESAN N DIMETHYLNITROSAMINE-DEMETHYLASE - ABSENCE OF INCREASED ENZYME CATABOLISM AND MULTIPLICITY OF EFFECTOR SITES IN REPRESSION - HEMOPROTEIN INVOLVEMENT	54	5
4259	12	3059 1976 CROATICA CHEMICA ACTA 48(1):69-86 RUCKPAUL K; MARICIC S; JANIG GR; BENKO B; VUKPAVLOVIC S; REIN H HEPATIC CYTOCHROME-P-450 - PROTON MAGNETIC-RELAXATION STUDY OF MICROSOMAL, SOLUBILIZED AND PARTIALLY RECONSTITUTED ENZYME- SYSTEM	19	5
4260	2	3077 1976 ENVIRONMENTAL HEALTH PERSPECTIVES 16(AUG):127-138 BOYD MR ROLE OF METABOLIC ACTIVATION IN PATHOGENESIS OF CHEMICALLY- INDUCED PULMONARY-DISEASE - MECHANISM OF ACTION OF LUNG-TOXIC FURAN, 4-IPOMEANOL	69	5
4261	4	3150 1976 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 198(3):709-715 GREINER JW; KRAMER RE; JARRELL J; COLBY HD MECHANISM OF ACTION OF SPIRONOLACTONE ON ADRENOCORTICAL FUNCTION IN GUINEA-PIGS	36	5
4262	2	3159 1976 JOURNAL OF THE FISHERIES RESEARCH BOARD OF CANADA 33(4):666-675 PEDERSEN MG; HERSHBERGER WK; ZACHARIAH PK; JUCHAU MR HEPATIC BIOTRANSFORMATION OF ENVIRONMENTAL XENOBIOTICS IN 6 STRAINS OF RAINBOW-TROUT (SALMO-GAIRDNERI)	51	5
4263	6	3172 1976 MUTATION RESEARCH 35(3):415-422 GUTTENPLAN JB; HUTTERER F; GARRO AJ EFFECTS OF CYTOCHROME P-448 AND P-450 INDUCERS ON MICROSOMAL DIMETHYLNITROSAMINE DEMETHYLASE ACTIVITY AND CAPACITY OF ISOLATED MICROSOMES TO ACTIVATE DIMETHYLNITROSAMINE TO A MUTAGEN	51	5
4264	6	3231 1977 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 1(1):33-38 THURMAN RG; BRENTZEL HJ ROLE OF ALCOHOL-DEHYDROGENASE IN MICROSOMAL ETHANOL OXIDATION AND ADAPTIVE INCREASE IN ETHANOL-METABOLISM DUE TO CHRONIC TREATMENT WITH ETHANOL	28	5
4265	5	3250 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 184(1):222-236 TISCHLER ME; FRIEDRICHS D; COLL K; WILLIAMSON JR PYRIDINE-NUCLEOTIDE DISTRIBUTIONS AND ENZYME MASS-ACTION RATIOS IN HEPATOCYTES FROM FED AND STARVED RATS	147	5
4266	5	3347 1977 ENDOCRINOLOGY 100(4):1129-1136 LAMAS L; TAUROG A IMPORTANCE OF THYROGLOBULIN STRUCTURE IN THYROID PEROXIDASE- CATALYZED CONVERSION OF DIIODOTYROSINE TO THYROXINE	32	5
4267	6	3414 1977 JOURNAL OF MEDICINAL CHEMISTRY 20(9):1194-1199 BOBIK A; HOLDER GM; RYAN AJ INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASE .3. INHIBITION OF HEPATIC MICROSOMAL ANILINE HYDROXYLASE AND AMINOPYRINE DEMETHYLASE BY 2,6-DIHYDROXYPHENYL ALKYL KETONE AND 2,4- DIHYDROXYPHENYL ALKYL KETONE AND RELATED COMPOUNDS	13	5
4268	10	3436 1977 MOLECULAR PHARMACOLOGY 13(1):15-30 NOVAK RF; KAPETANOVIC IM; MIEYAL JJ NUCLEAR MAGNETIC-RESONANCE STUDIES OF SUBSTRATE-HEMOPROTEIN COMPLEXES IN SOLUTION .1. INTERACTION OF XYLIDINE WITH MYOGLOBIN, HEMOGLOBIN, AND CYTOCHROME P450	22	5
4269	5	3505 1978 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 85(3):1007-1016 RAZZOUK C; AGAZZILEONARD E; CUMPS J; PONCELET F; MERCIER M; ROBERFROID M INDUCTION, MODIFICATION AND INHIBITION OF RAT-LIVER MICROSOMAL BENZO(A)PYRENE HYDROXYLASE - CORRELATION WITH S-9-MEDIATED MUTAGENICITY OF BENZO(A)PYRENE	15	5
4270	31	3515 1978 BIOCHEMICAL PHARMACOLOGY 27(5):627-633 VANDENBERG AP; NOORDHOEK J; SAVENIJECHAPEL EM; KOOPMANKOOL E DEVELOPMENT OF SEX-DIFFERENCES IN DEMETHYLATION OF ETHYLMORPHINE AND IN ITS INTERACTION WITH COMPONENTS OF HEPATIC MICROSOMAL CYTOCHROME P450 SYSTEM IN MICE	22	5
4271	16	3542 1978 BIOCHIMICA ET BIOPHYSICA ACTA 512(1):136-146 BECKER JF; MEEHAN T; BARTHOLOMEW JC FATTY-ACID REQUIREMENTS AND TEMPERATURE-DEPENDENCE OF MONO- OXYGENASE ACTIVITY IN RAT-LIVER MICROSOMES	18	5
4272	11	3552 1978 BIOCHIMICA ET BIOPHYSICA ACTA 540(3):443-454 BARON J; REDICK JA; KAPKE GF; VANORDEN LS IMMUNOHISTOCHEMICAL LOCALIZATION OF ADRENAL FERREDOXIN AND DISTRIBUTION OF ADRENAL FERREDOXIN AND CYTOCHROME-P-450 IN RAT ADRENAL	19	5
4273	4	3604 1978 FEBS LETTERS 91(2):169-172 DAWSON AG; COONEY GJ RECONSTRUCTION OF ALPHA-GLYCEROLPHOSPHATE SHUTTLE USING RAT- KIDNEY MITOCHONDRIA	9	5
4274	11	3661 1978 LIFE SCIENCES 22(12):1097-1102 BARON J; REDICK JA; GREENSPAN P; TAIRA Y IMMUNOHISTOCHEMICAL LOCALIZATION OF NADPH-CYTOCHROME-C REDUCTASE IN RAT-LIVER	30	5
4275	10	3665 1978 NUTRITION REVIEWS 36(11):319-328 COON MJ OXYGEN ACTIVATION IN METABOLISM OF LIPIDS, DRUGS AND CARCINOGENS	36	5
4276	10	3728 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):483-494 SIPAL Z; ANZENBACHER P; PUTZ Z; CHLUMSKY J; KRIVANOVA O INTERACTION OF CYTOCHROME-P-450 WITH HYDROCARBONS	10	5
4277	4	3750 1979 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 87(2):524-531 NAKAJIN S; ISHII Y; SHINODA M; SHIKITA M BINDING OF TRITON X-100 TO PURIFIED CYTOCHROME P-450SCC AND ENHANCEMENT OF THE CHOLESTEROL SIDE-CHAIN CLEAVAGE ACTIVITY	12	5
4278	19	3763 1979 BIOCHEMICAL PHARMACOLOGY 28(1):31-36 VANDENBERG AP; NOORDHOEK J; KOOPMANKOOL E RELATION BETWEEN SEX-DEPENDENCY OF TYPE-I BINDING OF ETHYLMORPHINE AND 1-BUTANOL-INDUCED SPECTRAL CHANGE IN MOUSE- LIVER MICROSOMES	5	5
4279	10	3790 1979 BIOCHEMISTRY 18(7):1187-1191 CEDERBAUM AI; DICKER E; RUBIN E; COHEN G EFFECT OF THIOUREA ON MICROSOMAL OXIDATION OF ALCOHOLS AND ASSOCIATED MICROSOMAL FUNCTIONS	61	5
4280	5	3806 1979 BRITISH JOURNAL OF PHARMACOLOGY 67(1):93-101 BORYS HK; INGALL GB; KARLER R DEVELOPMENT OF TOLERANCE TO THE PROLONGATION OF HEXOBARBITONE SLEEPING TIME CAUSED BY CANNABIDIOL	19	5
4281	3	3807 1979 CANCER RESEARCH 39(3):793-796 MCCOY GD; CHEN CHB; HECHT SS; MCCOY EC ENHANCED METABOLISM AND MUTAGENESIS OF NITROSOPYRROLIDINE IN LIVER FRACTIONS-ISOLATED FROM CHRONIC ETHANOL-CONSUMING HAMSTERS	70	5
4282	3	3842 1979 FEBS LETTERS 97(1):141-146 REILLY PEB; IVEY DE INHIBITION BY CHLORAMPHENICOL OF THE MICROSOMAL MONO-OXYGENASE COMPLEX OF RAT-LIVER	23	5
4283	7	3868 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(1):83-87 BERNSTINE EG GENETIC-CONTROL OF MITOCHONDRIAL MALIC ENZYME IN MOUSE-BRAIN	21	5
4284	10	3921 1979 MOLECULAR AND CELLULAR ENDOCRINOLOGY 15(3):111-133 SMITH SL; BOLLENBACHER WE; COOPER DY; SCHLEYER H; WIELGUS JJ; GILBERT LI ECDYSONE 20 MONOOXYGENASE - CHARACTERIZATION OF AN INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE	55	5
4285	10	3936 1979 PHARMACOLOGY & THERAPEUTICS 4(1):155-181 BOLT HM METABOLISM OF ESTROGENS - NATURAL AND SYNTHETIC	85	5
4286	4	4006 1980 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 93(3):797-803 BERRIGAN MJ; GURTOO HL; SHARMA SD; STRUCK RF; MARINELLO AJ PROTECTION BY N-ACETYLCYSTEINE OF CYCLOPHOSPHAMIDE METABOLISM- RELATED INVIVO DEPRESSION OF MIXED-FUNCTION OXYGENASE ACTIVITY AND INVITRO DENATURATION OF CYTOCHROME-P-450	29	5
4287	13	4022 1980 BIOCHEMICAL PHARMACOLOGY 29(1):89-95 GUENTHNER TM; KAHL GF; NEBERT DW NADPH-CYTOCHROME P-450 REDUCTASE - PREFERENTIAL INHIBITION BY ELLIPTICINE AND OTHER TYPE-II COMPOUNDS HAVING LITTLE EFFECT ON NADPH-CYTOCHROME-C REDUCTASE	26	5
4288	12	4051 1980 BIOCHIMICA ET BIOPHYSICA ACTA 613(1):52-61 WOODS LFJ; WISEMAN A BENZO(A)PYRENE HYDROXYLASE FROM SACCHAROMYCES-CEREVISIAE - SUBSTRATE BINDING, SPECTRAL AND KINETIC DATA	18	5
4289	9	4076 1980 CHEMICO-BIOLOGICAL INTERACTIONS 29(3):277-289 PARKINSON A; COCKERLINE R; SAFE S POLYCHLORINATED BIPHENYL ISOMERS AND CONGENERS AS INDUCERS OF BOTH 3-METHYLCHOLANTHRENE-TYPE AND PHENOBARBITONE-TYPE MICROSOMAL-ENZYME ACTIVITY	97	5
4290	7	4105 1980 FEBS LETTERS 109(1):71-74 OHTAKI S; NAKAGAWA H; YAMAZAKI I REACTION OF DETERGENT-SOLUBILIZED THYROID PEROXIDASE WITH HYDROGEN-PEROXIDE	14	5
4291	3	4109 1980 FEBS LETTERS 119(1):33-37 CAPDEVILA J; ORRENIUS S METABOLISM OF BENZO[A]PYRENE-3,6-QUINONE BY ISOLATED HEPATOCYTES	15	5
4292	4	4171 1980 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 13(5):545-550 MORISAKI M; DUQUE C; IKEKAWA N; SHIKITA M SUBSTRATE-SPECIFICITY OF ADRENOCORTICAL CYTOCHROME P-450SCC .1. EFFECT OF STRUCTURAL MODIFICATION OF CHOLESTEROL SIDE-CHAIN ON PREGNENOLONE PRODUCTION	36	5
4293	5	4181 1980 LIFE SCIENCES 26(6):481-487 MCMANUS ME; BOOBIS AR; PACIFICI GM; FREMPONG RY; BRODIE MJ; KAHN GC; WHYTE C; DAVIES DS XENOBIOTIC METABOLISM IN THE HUMAN-LUNG	36	5
4294	9	4184 1980 LIFE SCIENCES 27(25-2):2465-2470 REDICK JA; KAWABATA TT; GUENGERICH FP; KRIETER PA; SHIRES TK; BARON J DISTRIBUTIONS OF MONO-OXYGENASE COMPONENTS AND EPOXIDE HYDRATASE WITHIN THE LIVERS OF UNTREATED MALE-RATS	28	5
4295	1	4196 1980 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 12(1):13-27 LESKOVAC V; POPOVIC M MECHANISM OF REDUCTION OF NITROFURANTOIN ON LIVER-MICROSOMES	9	5
4296	5	4211 1980 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 77(8):4648-4652 RAY DB; HORST IA; KOWAL J ADRENOCORTICOTROPIC HORMONE INCREASES SPECIFIC PROTEINS OF THE MITOCHONDRIAL-FRACTION THAT ARE TRANSLATED INSIDE OR OUTSIDE THIS ORGANELLE IN CULTURED ADRENAL-TUMOR CELLS	16	5
4297	4	4255 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 209(1):137-142 THURMAN RG; REINKE LA; BELINSKY S; EVANS RK; KAUFFMAN FC CO-REGULATION OF THE MIXED-FUNCTION OXIDATION OF PARA- NITROANISOLE AND GLUCURONIDATION OF PARA-NITROPHENOL IN THE PERFUSED-RAT-LIVER BY CARBOHYDRATE RESERVES	43	5
4298	6	4264 1981 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 212(1):136-146 PROUGH RA; SAEKI Y; CAPDEVILA J THE METABOLISM OF BENZO[A]PYRENE PHENOLS BY RAT-LIVER MICROSOMAL FRACTIONS	10	5
4299	17	4290 1981 BIOCHEMICAL PHARMACOLOGY 30(10):1091-1097 VODICNIK MJ; FRANKLIN RB; ELCOMBE CR; LECH JJ SEX STEROIDS AND DRUG-METABOLISM - A SEX-RELATED DIFFERENCE IN HEPATIC-MICROSOMAL ETHOXYRESORUFIN-O-DEETHYLATION IN SPRAGUE- DAWLEY RATS	33	5
4300	12	4306 1981 BIOCHIMICA ET BIOPHYSICA ACTA 649(2):343-354 YAMAKURA F; KIDO T; KIMURA T CHARACTERIZATION OF CYTOCHROME P-450SCC-CONTAINING LIPOSOMES	20	5

#	Cited nodes	Nodes / Authors	GCS	LCS
4301	43	4353 1981 ESSAYS IN BIOCHEMISTRY 17():85-126 PAINE AJ HEPATIC CYTOCHROME-P-450	25	5
4302	18	4363 1981 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 362(8):1091-1099 MULLERENOCH D; SATO N; THOMAS H O-DEMETHYLATION OF SCOPARONE AND STUDIES ON THE SCOPARONE- INDUCED SPECTRAL CHANGE OF CYTOCHROME-P-450 IN RAT-LIVER MICROSOMES	17	5
4303	9	4366 1981 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 13(7):843-& SWIERCZYNSKI J DISSIMILARITY OF CYTOSOL AND MITOCHONDRIAL MALIC ENZYME FROM RAT SKELETAL-MUSCLE	11	5
4304	8	4397 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(14):7536-7542 UENG TH; ALVARES AP SELECTIVE LOSS OF PULMONARY CYTOCHROME P-450I IN RABBITS PRETREATED WITH POLYCHLORINATED-BIPHENYLS	18	5
4305	16	4404 1981 JOURNAL OF LIPID RESEARCH 22(8):1254-1264 OFTEBRO H; SAAREM K; BJORKHEM I; PEDERSEN JI SIDE-CHAIN HYDROXYLATION OF C27-STEROIDS AND VITAMIN-D3 BY A CYTOCHROME-P-450 ENZYME-SYSTEM ISOLATED FROM HUMAN-LIVER MITOCHONDRIA	29	5
4306	7	4513 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 107(1):265-271 DEAN WL; GRAY RD HYDRODYNAMIC PROPERTIES OF MONOMERIC CYTOCHROME-P-450LM2 AND CYTOCHROME-P-450LM4 IN NORMAL-OCTYLGLUCOSIDE SOLUTION	11	5
4307	4	4575 1982 CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE 60(12):1463-1473 GRIFFIN BW USE OF SPIN TRAPS TO ELUCIDATE RADICAL MECHANISMS OF OXIDATIONS BY HYDROPEROXIDES CATALYZED BY HEMEPROTEINS	16	5
4308	12	4587 1982 CHEMICO-BIOLOGICAL INTERACTIONS 42(3):279-289 DELAFORGE M; IOANNIDES C; PARKE DV SELECTIVE-INHIBITION OF THE SAFROLE-INDUCED MIXED-FUNCTION OXIDASE ACTIVITIES BY 9-HYDROXYELLIPTICINE	10	5
4309	17	4637 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(2):761-766 OHTAKI S; NAKAGAWA H; NAKAMURA M; YAMAZAKI I REACTIONS OF PURIFIED HOG THYROID PEROXIDASE WITH H2O2, TYROSINE, AND METHYLMERCAPTOIMIDAZOLE (GOITROGEN) IN COMPARISON WITH BOVINE LACTOPEROXIDASE	88	5
4310	8	4722 1982 XENOBIOTICA 12(1):9-17 RENDIC S; ALEBICKOLBAH T; KAJFEZ F; RUF HH INTERACTION OF RANITIDINE WITH LIVER-MICROSOMES	65	5
4311	11	4764 1983 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 227(1):329-338 CEDERBAUM AI ORGANIC HYDROPEROXIDE-DEPENDENT OXIDATION OF ETHANOL BY MICROSOMES - LACK OF A ROLE FOR FREE HYDROXYL RADICALS	11	5
4312	6	4767 1983 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 110(2):646-653 WHEELER EL CYTOCHROME-P-450 MEDIATED INTERACTION BETWEEN HYDROPEROXIDE AND MOLECULAR-OXYGEN - A PROPOSED METHOD FOR P-450 KINETIC-STUDIES	11	5
4313	6	4768 1983 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 113(1):332-339 RENNEBERG R; DAMERAU W; JUNG C; EBERT B; SCHELLER F STUDY OF H2O2-SUPPORTED N-DEMETHYLATIONS CATALYZED BY CYTOCHROME-P-450 AND HORSERADISH-PEROXIDASE	8	5
4314	5	4781 1983 BIOCHEMICAL PHARMACOLOGY 32(4):665-670 REITER R; WENDEL A DRUG-INDUCED LIPID-PEROXIDATION IN MICE .4. INVITRO HYDROCARBON EVOLUTION, REDUCTION OF OXYGEN AND COVALENT BINDING OF ACETAMINOPHEN	29	5
4315	8	4789 1983 BIOCHEMICAL PHARMACOLOGY 32(20):3027-3035 PASCOE GA; SAKAIWONG J; SOLIVEN E; CORREIA MA REGULATION OF INTESTINAL CYTOCHROME-P-450 AND HEME BY DIETARY NUTRIENTS - CRITICAL ROLE OF SELENIUM	30	5
4316	17	4819 1983 BIOMEDICA BIOCHIMICA ACTA 42(6):651-662 ROHDE K; BLANCK J; RUCKPAUL K KINETICS OF ELEMENTARY STEPS IN THE CYTOCHROME-P-450 REACTION SEQUENCE .6. MODEL TREATMENT OF THE NADPH-DEPENDENT 1ST ELECTRON-TRANSFER REACTION BETWEEN CYTOCHROME-P-450 REDUCTASE AND CYTOCHROME-P-450 LM2 IN SOLUTION	5	5
4317	6	4906 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(4):2079-2082 RAWITCH AB; CHERNOFF SB; LITWER MR; ROUSE JB; HAMILTON JW THYROGLOBULIN STRUCTURE-FUNCTION - THE AMINO-ACID-SEQUENCE SURROUNDING THYROXINE	77	5
4318	8	4907 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(4):2593-2598 ROOME PW; PHILLEY JC; PETERSON JA PURIFICATION AND PROPERTIES OF PUTIDAREDOXIN REDUCTASE	33	5
4319	2	4914 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(6):3855-3858 KALYANARAMAN B; MOTTLEY C; MASON RP A DIRECT ELECTRON-SPIN RESONANCE AND SPIN-TRAPPING INVESTIGATION OF PEROXYL FREE-RADICAL FORMATION BY HEMATIN HYDROPEROXIDE SYSTEMS	102	5
4320	13	4971 1983 MOLECULAR PHARMACOLOGY 24(1):137-145 MILLER MS; HUANG MT; JEFFREY AM; CONNEY AH BETAMETHASONE-MEDIATED ACTIVATION OF BIPHENYL 2-HYDROXYLATION IN RAT-LIVER MICROSOMES - STUDIES ON POSSIBLE MECHANISMS	12	5
4321	6	4985 1983 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 80(21):6680-6684 BURKA LT; PLUCINSKI TM; MACDONALD TL MECHANISMS OF HYDROXYLATION BY CYTOCHROME-P-450 - METABOLISM OF MONOHALOBENZENES BY PHENOBARBITAL-INDUCED MICROSOMES	36	5
4322	2	5018 1984 ALCOHOL AND ALCOHOLISM 19(2):101-107 YUKI T; HASHIMOTO T; OHKUMA S; TAMURA J; KURIYAMA K ALTERATION OF ACETALDEHYDE METABOLISM IN CARBON TETRACHLORIDE- INTOXICATED RAT-LIVER - ANALYSIS USING LIVER PERFUSION SYSTEM	7	5
4323	6	5029 1984 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 231(2):416-423 DOHN DR; KRIEGER RI N-DEMETHYLATION OF PARA-CHLORO-N-METHYLANILINE CATALYZED BY SUBCELLULAR-FRACTIONS FROM THE AVOCADO PEAR (PERSEA-AMERICANA)	14	5
4324	4	5078 1984 BIOCHIMICA ET BIOPHYSICA ACTA 794(1):110-124 TURK J; COLCA JR; KOTAGAL N; MCDANIEL ML ARACHIDONIC-ACID METABOLISM IN ISOLATED PANCREATIC-ISLETS .1. IDENTIFICATION AND QUANTITATION OF LIPOXYGENASE AND CYCLOOXYGENASE PRODUCTS	61	5
4325	8	5079 1984 BIOCHIMICA ET BIOPHYSICA ACTA 795(2):384-391 OLIW EH BIOSYNTHESIS OF 5,6-DIHYDROXYPROSTAGLANDIN-E1 AND F1-ALPHA FROM 5,6-DIHYDROXYEICOSATRIENOIC ACID BY RAM SEMINAL-VESICLES	10	5
4326	4	5147 1984 INORGANIC CHEMISTRY 23(19):2932-2935 GOLD A; IVEY W; TONEY GE; SANGAIAH R FERRIC ISOPORPHYRINS FROM HYDROPEROXIDE OXIDATION OF (TETRAPHENYLPORPHINATO)IRON(III) COMPLEXES	37	5
4327	6	5199 1984 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 106(7):2182-2185 REID LS; MAUK MR; MAUK AG ROLE OF HEME PROPIONATE GROUPS IN CYTOCHROME-B5 ELECTRON- TRANSFER	72	5
4328	12	5282 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 241(2):397-402 LIU Z; FRANKLIN MR CYTOCHROME-P-450 LIGANDS - METYRAPONE REVISITED	11	5
4329	7	5289 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 128(1):1-6 NAKAJIMA R; YAMAZAKI I; GRIFFIN BW SPECTRA OF CHLOROPEROXIDASE COMPOUND-II AND COMPOUND-III	28	5
4330	10	5302 1985 BIOCHEMICAL PHARMACOLOGY 34(9):1407-1413 ANDERSSON T; FORLIN L SPECTRAL PROPERTIES OF SUBSTRATE CYTOCHROME-P-450 INTERACTION AND CATALYTIC ACTIVITY OF XENOBIOTIC METABOLIZING ENZYMES IN ISOLATED RAINBOW-TROUT LIVER-CELLS	19	5
4331	12	5303 1985 BIOCHEMICAL PHARMACOLOGY 34(9):1507-1513 CRAFT JA EFFECTS OF PYRAZOLE ON NITROSODIMETHYLAMINE DEMETHYLASE AND OTHER MICROSOMAL XENOBIOTIC METABOLIZING ACTIVITIES	17	5
4332	12	5309 1985 BIOCHEMICAL PHARMACOLOGY 34(17):3137-3142 MCKILLOP D EFFECTS OF PHENOBARBITONE AND BETA-NAPHTHOFLAVONE ON HEPATIC- MICROSOMAL DRUG-METABOLIZING ENZYMES OF THE MALE BEAGLE DOG	26	5
4333	7	5368 1985 DRUG METABOLISM AND DISPOSITION 13(1):58-61 KEDDERIS GL; RICKERT DE LOSS OF RAT-LIVER MICROSOMAL CYTOCHROME-P-450 DURING METHIMAZOLE METABOLISM - ROLE OF FLAVIN-CONTAINING MONOOXYGENASE	40	5
4334	9	5384 1985 ENVIRONMENTAL HEALTH PERSPECTIVES 64():69-84 CAVALIERI E; ROGAN E ROLE OF RADICAL CATIONS IN AROMATIC HYDROCARBON CARCINOGENESIS	111	5
4335	11	5420 1985 JOURNAL OF BIOCHEMISTRY 97(5):1263-1271 NONAKA Y; FUJII S; YAMANO T P-31 NUCLEAR MAGNETIC-RESONANCE AND ELECTRONIC SPECTROSCOPIC STUDIES OF ADRENODOXIN REDUCTASE AND ITS BINARY COMPLEX WITH NADP+	10	5
4336	3	5445 1985 JOURNAL OF INTERFERON RESEARCH 5(2):265-272 FRANKLIN MR; FINKLE BS EFFECT OF MURINE GAMMA-INTERFERON ON THE MOUSE-LIVER AND ITS DRUG-METABOLIZING-ENZYMES - COMPARISON WITH HUMAN HYBRID ALPHA- INTERFERON	27	5
4337	3	5595 1986 BIOLOGICHESKIE MEMBRANY 3(8):838-845 RASHBA YE; CHERNIKOV VA; BAIDER LM; VARTANYAN LS APPLICATION OF PIPERIDINE AND IMIDAZOLINE HYDROXYLAMINES FOR ELECTRON-SPIN-RESONANCE QUANTITATION OF SUPEROXIDE RADICALS IN BIOCHEMICAL SYSTEMS	22	5
4338	11	5615 1986 CHEMICO-BIOLOGICAL INTERACTIONS 58(3):289-299 LEWIS DFV; TAMBURINI PP; GIBSON GG THE INTERACTION OF A HOMOLOGOUS SERIES OF HYDROCARBONS WITH HEPATIC CYTOCHROME-P-450 - MOLECULAR ORBITAL-DERIVED ELECTRONIC AND STRUCTURAL PARAMETERS INFLUENCING THE HEMOPROTEIN SPIN STATE	16	5
4339	68	5626 1986 CRC CRITICAL REVIEWS IN BIOCHEMISTRY 20(2):139-200 WEINER LM MAGNETIC-RESONANCE STUDY OF THE STRUCTURE AND FUNCTIONS OF CYTOCHROME-P450	21	5
4340	6	5635 1986 DRUG METABOLISM AND DISPOSITION 14(2):208-213 GUENTHNER TM; KARNEZIS TA MULTIPLE EPOXIDE HYDROLASES IN HUMAN-LUNG	13	5
4341	10	5682 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(8):3790-3799 KAWATA S; TRZASKOS JM; GAYLOR JL AFFINITY-CHROMATOGRAPHY OF MICROSOMAL-ENZYMES ON IMMOBILIZED DETERGENT-SOLUBILIZED CYTOCHROME-B5	17	5
4342	8	5695 1986 JOURNAL OF HYPERTENSION 4():S33-S42 CARROLL MA; SCHWARTZMAN M; ABRAHAM NG; PINTO A; MCGIFF JC CYTOCHROME-P450-DEPENDENT ARACHIDONATE METABOLISM IN RENOMEDULLARY CELLS - FORMATION OF NA+K+-ATPASE INHIBITOR	7	5
4343	4	5699 1986 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 237(1):107-113 GALINSKY RE; KANE RE; FRANKLIN MR EFFECT OF AGING ON DRUG-METABOLIZING-ENZYMES IMPORTANT IN ACETAMINOPHEN ELIMINATION	42	5
4344	8	5737 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 82(2):272-280 PATHIRATNE A; PUYEAR RL; BRAMMER JD A COMPARATIVE-STUDY OF THE EFFECTS OF BENZENE, TOLUENE, AND XYLENES ON THEIR INVITRO METABOLISM AND DRUG-METABOLIZING- ENZYMES IN RAT-LIVER	43	5
4345	8	5793 1987 BIOCHEMICAL PHARMACOLOGY 36(10):1741-1747 BEDNAR MM; KRAEMER R; ABRAHAM NG; MULLANE KM ARACHIDONIC-ACID MONOOXYGENASE AND LIPOXYGENASE ACTIVITIES IN POLYMORPHONUCLEAR LEUKOCYTES	19	5
4346	4	5817 1987 BIOCHEMISTRY INTERNATIONAL 15(1):55-63 BELEZNAI Z; JANCSIK V PURIFICATION OF L-3-GLYCEROPHOSPHATE DEHYDROGENASE FROM RAT- LIVER MITOCHONDRIA	6	5
4347	2	5823 1987 BIOCHIMICA ET BIOPHYSICA ACTA 893(3):398-408 KORETSKY AP; BALABAN RS CHANGES IN PYRIDINE-NUCLEOTIDE LEVELS ALTER OXYGEN-CONSUMPTION AND EXTRA-MITOCHONDRIAL PHOSPHATES IN ISOLATED-MITOCHONDRIA - A P-31-NMR AND NAD(P)H FLUORESCENCE STUDY	84	5
4348	9	5847 1987 CARCINOGENESIS 8(7):881-887 ROSSI M; MARKOVITZ S; CALLAHAN T DEFINING THE ACTIVE-SITE OF CYTOCHROME-P-450 - THE CRYSTAL AND MOLECULAR-STRUCTURE OF AN INHIBITOR, SKF-525A	11	5
4349	5	5911 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(3):966-973 POTTER DW; HINSON JA MECHANISMS OF ACETAMINOPHEN OXIDATION TO N-ACETYL-P- BENZOQUINONE IMINE BY HORSERADISH-PEROXIDASE AND CYTOCHROME-P- 450	64	5
4350	8	5921 1987 JOURNAL OF CLINICAL INVESTIGATION 80(6):1763-1769 NADLER JL; NATARAJAN R; STERN N SPECIFIC ACTION OF THE LIPOXYGENASE PATHWAY IN MEDIATING ANGIOTENSIN-II-INDUCED ALDOSTERONE SYNTHESIS IN ISOLATED ADRENAL GLOMERULOSA CELLS	106	5
4351	3	5983 1987 TOXICOLOGY AND APPLIED PHARMACOLOGY 87(1):141-154 GEORGELLIS A; MONTELIUS J; RYDSTROM J EVIDENCE FOR A FREE-RADICAL-DEPENDENT METABOLISM OF 7,12- DIMETHYLBENZ(A)ANTHRACENE IN RAT TESTIS	25	5
4352	15	6015 1988 AMERICAN JOURNAL OF THE MEDICAL SCIENCES 295(4):268-274 CARROLL MA; SCHWARTZMAN M; SACERDOTI D; MCGIFF JC NOVEL RENAL ARACHIDONATE METABOLITES	14	5
4353	6	6056 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 155(1):379-383 KAGIMOTO K; MCCARTHY JL; WATERMAN MR; KAGIMOTO M DEDUCED AMINO-ACID SEQUENCE OF MATURE CHICKEN TESTIS FERREDOXIN	19	5
4354	3	6074 1988 BIOCHEMICAL PHARMACOLOGY 37(5):849-854 BANHEGYI G; GARZO T; MESZAROS G; FARAGO A; ANTONI F; MANDL J CYCLIC AMP-DEPENDENT PHOSPHORYLATION IN THE CONTROL OF BIOTRANSFORMATION IN THE LIVER	17	5
4355	9	6080 1988 BIOCHEMICAL PHARMACOLOGY 37(10):1971-1979 BEYELER S; TESTA B; PERRISSOUD D FLAVONOIDS AS INHIBITORS OF RAT-LIVER MONOOXYGENASE ACTIVITIES	45	5
4356	4	6081 1988 BIOCHEMICAL PHARMACOLOGY 37(11):2223-2229 AUSTIN CA; SHEPHARD EA; PIKE SF; RABIN BR; PHILLIPS IR THE EFFECT OF TERPENOID COMPOUNDS ON CYTOCHROME-P-450 LEVELS IN RAT-LIVER	37	5
4357	14	6108 1988 BIOCHEMISTRY 27(4):1147-1153 NARASIMHULU S QUENCHING OF TRYPTOPHANYL FLUORESCENCE OF BOVINE ADRENAL P- 450C-21 AND INHIBITION OF SUBSTRATE BINDING BY ACRYLAMIDE	10	5
4358	11	6129 1988 BIOCHIMICA ET BIOPHYSICA ACTA 966(1):133-149 VANROLLINS M; FRADE PD; CARRETERO OA OXIDATION OF 5,8,11,14,17-EICOSAPENTAENOIC ACID BY HEPATIC AND RENAL MICROSOMES	20	5
4359	4	6148 1988 CARCINOGENESIS 9(3):357-364 DJURIC Z; FIFER EK; YAMAZOE Y; BELAND FA DNA-BINDING BY 1-NITROPYRENE AND 1,6-DINITROPYRENE INVITRO AND INVIVO - EFFECTS OF NITROREDUCTASE INDUCTION	54	5
4360	15	6181 1988 DRUG METABOLISM AND DISPOSITION 16(1):1-8 NEBERT DW THE 1986 BRODIE,BERNARD,B. AWARD LECTURE - THE GENETIC- REGULATION OF DRUG-METABOLIZING-ENZYMES	9	5
4361	10	6221 1988 JOURNAL OF BIOCHEMICAL TOXICOLOGY 3():191-212 WINSTON GW; NARAYAN S ALTERATION OF LIVER MICROSOMAL MONOOXYGENASES AND SUBSTRATE COMPETITION WITH ANILINE HYDROXYLASE FROM RATS CHRONICALLY FED LOW-FAT AND HIGH-FAT CONTAINING ALCOHOL DIETS	12	5
4362	3	6226 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(7):3348-3353 CRUSE I; MAINES MD EVIDENCE SUGGESTING THAT THE 2 FORMS OF HEME OXYGENASE ARE PRODUCTS OF DIFFERENT GENES	156	5
4363	18	6243 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17418-17421 CUPP JR; VICKERY LE IDENTIFICATION OF FREE AND [FE2S2]-BOUND CYSTEINE RESIDUES OF ADRENODOXIN	33	5
4364	8	6244 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(33):17566-17575 KRISHNAMOORTHY G; HINKLE PC STUDIES ON THE ELECTRON-TRANSFER PATHWAY, TOPOGRAPHY OF IRON- SULFUR CENTERS, AND SITE OF COUPLING IN NADH-Q OXIDOREDUCTASE	68	5
4365	3	6271 1988 LIPIDS 23(11):1015-1018 FAHLSTADIUS P CIS-9, 10-EPOXYSTEARIC ACID IN HUMAN-LEUKOCYTES - ISOLATION AND QUANTITATIVE-DETERMINATION	16	5
4366	10	6321 1988 TOXICOLOGY AND APPLIED PHARMACOLOGY 94(1):1-10 ERICKSON DA; GOODRICH MS; LECH JJ THE EFFECT OF PIPERONYL BUTOXIDE ON HEPATIC CYTOCHROME-P-450- DEPENDENT MONOOXYGENASE ACTIVITIES IN RAINBOW-TROUT (SALMO- GAIRDNERI)	21	5
4367	3	6345 1989 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 18():1-12 PACEASCIAK CR DESCRIPTION OF PATHWAYS	14	5
4368	5	6392 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(2):273-280 JOHNSON EF; FINLAYSON M; HUJSAK CM; PENDURTHI UR; TUKEY RH GENETIC CONTRIBUTIONS TO THE VARIATION AMONG RABBITS OF LIVER MICROSOMAL DEOXYCORTICOSTERONE SYNTHESIS	7	5
4369	9	6397 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 275(1):140-150 VIND C; DICH J; GRUNNET N EFFECTS OF CYTOCHROME-P450-INDUCING AGENTS ON THE MONOOXYGENATION OF TESTOSTERONE IN LONG-TERM CULTURES OF HEPATOCYTES FROM MALE AND FEMALE RATS	13	5
4370	4	6488 1989 BIOCHIMICA ET BIOPHYSICA ACTA 1007(2):192-195 SRIVASTAVA G; BAWDEN MJ; ANDERSON A; MAY BK DRUG INDUCTION OF P450IIB1/IIB2 AND 5-AMINOLEVULINATE SYNTHASE MESSENGER-RNAS IN RAT-TISSUES	12	5
4371	3	6492 1989 BIOPHYSICAL JOURNAL 55(4):621-630 ENG J; LYNCH RM; BALABAN RS NICOTINAMIDE ADENINE-DINUCLEOTIDE FLUORESCENCE SPECTROSCOPY AND IMAGING OF ISOLATED CARDIAC MYOCYTES	83	5
4372	3	6499 1989 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 67(8):912-921 KARMAZYN M SYNTHESIS AND RELEVANCE OF CARDIAC EICOSANOIDS WITH PARTICULAR EMPHASIS ON ISCHEMIA AND REPERFUSION	37	5
4373	10	6558 1989 DRUG METABOLISM AND DISPOSITION 17(4):360-364 KHAN WA; KUHN C; MERK HF; PARK SS; GELBOIN HV; BICKERS DR; MUKHTAR H ISOZYME-SPECIFIC MONOCLONAL ANTIBODY-DIRECTED ASSESSMENT OF INDUCTION OF HEPATIC CYTOCHROME-P-450 BY CLOTRIMAZOLE	6	5
4374	2	6560 1989 DRUG METABOLISM AND DISPOSITION 17(5):481-486 ROBERTS AE; LACY SA; PILON D; TURNER MJ; RICKERT DE METABOLISM OF ACRYLONITRILE TO 2-CYANOETHYLENE OXIDE IN F344 RAT-LIVER MICROSOMES, LUNG MICROSOMES, AND LUNG-CELLS	30	5
4375	13	6561 1989 DRUG METABOLISM AND DISPOSITION 17(5):487-494 BULGER WH; KUPFER D CHARACTERISTICS OF MONOOXYGENASE-MEDIATED COVALENT BINDING OF METHOXYCHLOR IN HUMAN AND RAT-LIVER MICROSOMES	15	5
4376	7	6572 1989 DRUG METABOLISM REVIEWS 20(2-4):765-779 HULLA JE; JUCHAU MR DEVELOPMENTAL ASPECTS OF P450IIIA - PRENATAL ACTIVITY AND INDUCIBILITY	10	5
4377	5	6584 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 181(2):391-396 UVAROV VY; TRETIAKOV VE; LESHCHENKO AV; RUKAVISHNIKOV IG; DZHUZENOVA CS; TRETIAKOVA LZ; ARCHAKOV AI EFFECT OF THE MICROENVIRONMENT ON THE TERTIARY STRUCTURE OF CYTOCHROME-P-450 LM2	13	5
4378	7	6590 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 186(1-2):383-388 HILDEBRANDT P; GARDA H; STIER A; BACHMANOVA GI; KANAEVA IP; ARCHAKOV AI PROTEIN PROTEIN INTERACTIONS IN MICROSOMAL CYTOCHROME-P-450 ISOZYME LM2 AND THEIR EFFECT ON SUBSTRATE BINDING	16	5
4379	1	6634 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(8):4679-4683 PROCHAZKA M; KOZAK UC; KOZAK LP A GLYCEROL-3-PHOSPHATE DEHYDROGENASE NULL MUTANT IN BALB/CHEA MICE	20	5
4380	8	6675 1989 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 249(2):667-672 SHERRATT AJ; BANET DE; LINDER MW; PROUGH RA POTENTIATION OF 3-METHYLCHOLANTHRENE INDUCTION OF RAT HEPATIC CYTOCHROME-P450IA1 BY DEXAMETHASONE INVIVO	21	5
4381	5	6685 1989 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 111(17):6621-6627 LABEQUE R; MARNETT LJ HOMOLYTIC AND HETEROLYTIC SCISSION OF ORGANIC HYDROPEROXIDES BY (MESO-TETRAPHENYLPORPHINATO)IRON(III) AND ITS RELATION TO OLEFIN EPOXIDATION	74	5
4382	9	6702 1989 MOLECULAR CARCINOGENESIS 2(5):261-267 HANSEN SK; ROSS JA; SIEGFRIED JM; LEAVITT S; RUDO K; LANGENBACH R; NESNOW S TRANSFECTION OF A RAT CYTOCHROME P450B CDNA INTO C3H10T1/2CL8 MOUSE EMBRYO FIBROBLASTS	10	5
4383	4	6709 1989 MOLECULAR PHARMACOLOGY 35(4):512-518 BELINSKY SA; KAUFFMAN FC; THURMAN RG INTERACTIONS BETWEEN GLYCOLYSIS AND MIXED-FUNCTION OXIDATION - STUDIES WITH 7-ETHOXYCOUMARIN IN PERFUSED LIVERS FROM BETA- NAPHTHOFLAVONE-TREATED RATS	9	5
4384	3	6718 1989 MOLECULAR PHARMACOLOGY 36(1):113-120 POLAND A; TEITELBAUM P; GLOVER E [I-125]2-IODO-3,7,8-TRICHLORODIBENZO-P-DIOXIN-BINDING SPECIES IN MOUSE-LIVER INDUCED BY AGONISTS FOR THE AH RECEPTOR - CHARACTERIZATION AND IDENTIFICATION	82	5
4385	14	6724 1989 MUTATION RESEARCH 213(1):83-90 VERGERES G; WINTERHALTER KH; RICHTER C MICROSOMAL CYTOCHROME-P-450 - SUBSTRATE BINDING, MEMBRANE INTERACTIONS, AND TOPOLOGY	7	5
4386	8	6735 1989 PATHOLOGY AND IMMUNOPATHOLOGY RESEARCH 8(2):104-112 CLAWSON GA MECHANISMS OF CARBON-TETRACHLORIDE HEPATOTOXICITY	39	5
4387	3	6761 1989 SCIENCE 244(4909):1176-1179 ORDWAY RW; WALSH JV; SINGER JJ ARACHIDONIC-ACID AND OTHER FATTY-ACIDS DIRECTLY ACTIVATE POTASSIUM CHANNELS IN SMOOTH-MUSCLE CELLS	283	5
4388	7	6773 1989 TOXICOLOGY AND APPLIED PHARMACOLOGY 101(2):179-195 YOST GS; BUCKPITT AR; ROTH RA; MCLEMORE TL CONTEMPORARY-ISSUES IN TOXICOLOGY - MECHANISMS OF LUNG INJURY BY SYSTEMICALLY ADMINISTERED CHEMICALS	31	5
4389	5	6791 1989 XENOBIOTICA 19(10):1175-1180 CLARKE SE; BREALEY CJ; GIBSON GG CYTOCHROME-P-450 IN THE HOUSEFLY - INDUCTION, SUBSTRATE- SPECIFICITY AND COMPARISON TO 3 RAT HEPATIC ISOENZYMES	9	5
4390	8	6827 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 277(1):42-46 ROBINSON RC; NAGATA K; GELBOIN HV; RIFKIND J; GONZALEZ FJ; FRIEDMAN FK DEVELOPMENTAL REGULATION OF HEPATIC TESTOSTERONE HYDROXYLASES - SIMULTANEOUS ACTIVATION AND REPRESSION OF CONSTITUTIVELY EXPRESSED CYTOCHROMES-P450 IN SENESCENT RATS	9	5
4391	8	6842 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 282(1):198-201 LARROQUE C; LANGE R; MAURIN L; BIENVENUE A; VANLIER JE ON THE NATURE OF THE CYTOCHROME P450SCC ULTIMATE OXIDANT - CHARACTERIZATION OF A PRODUCTIVE RADICAL INTERMEDIATE	16	5
4392	1	6857 1990 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 172(1):98-106 PASCAL S; TATON M; RAHIER A OXIDATIVE C4-DEMETHYLATION OF 24-METHYLENE CYCLOARTANOL BY A CYANIDE-SENSITIVE ENZYMATIC SYSTEM FROM HIGHER-PLANT MICROSOMES	11	5
4393	1	6886 1990 BIOCHEMICAL PHARMACOLOGY 40(3):529-533 HORBACH GJMJ; VANASTEN JG; VANBEZOOIJEN CFA THE INFLUENCE OF AGING ON THE INDUCTION OF THE MESSENGER-RNAS OF RAT-LIVER CYTOCHROME-P450IIB1 AND CYTOCHROME-P450IIB2	17	5
4394	10	6892 1990 BIOCHEMICAL PHARMACOLOGY 40(8):1707-1718 VANDENBOSSCHE H; WILLEMSENS G; ROELS I; BELLENS D; MOEREELS H; COENE MC; LEJEUNE L; LAUWERS W; JANSSEN PAJ R-76713 AND ENANTIOMERS - SELECTIVE, NONSTEROIDAL INHIBITORS OF THE CYTOCHROME-P450-DEPENDENT ESTROGEN SYNTHESIS	35	5
4395	9	6949 1990 BIOORGANIC CHEMISTRY 18(2):185-198 GANNETT PM; IVERSEN P; LAWSON T THE MECHANISM OF INHIBITION OF CYTOCHROME-P450IIE1 BY DIHYDROCAPSAICIN	19	5
4396	2	6958 1990 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 68(6):769-776 SQUIRES EJ; NEGISHI M TISSUE-SPECIFIC REGULATION OF CYTOCHROME-P-450 DEPENDENT TESTOSTERONE 15-ALPHA-HYDROXYLASE	8	5
4397	4	6972 1990 CANCER RESEARCH 50(22):7203-7205 MACDONALD MJ; WARNER TF; MERTZ RJ HIGH-ACTIVITY OF MITOCHONDRIAL GLYCEROL PHOSPHATE DEHYDROGENASE IN INSULINOMAS AND CARCINOID AND OTHER TUMORS OF THE AMINE PRECURSOR UPTAKE DECARBOXYLATION SYSTEM	13	5
4398	5	6995 1990 CHEMICO-BIOLOGICAL INTERACTIONS 76(2):181-192 HALL M; PARKER DK; GROVER PL; LU JYL; HOPKINS NE; ALWORTH WL EFFECTS OF 1-ETHYNYLPYRENE AND RELATED INHIBITORS OF P450 ISOZYMES UPON BENZO[A]PYRENE METABOLISM BY LIVER-MICROSOMES	22	5
4399	9	7003 1990 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 96(1):163-176 GUPTA RP; LAPADULA DM; ABOUDONIA MB PURIFICATION AND CHARACTERIZATION OF CYTOCHROME-P-450 ISOZYMES FROM PHENOBARBITAL-INDUCED ADULT HEN LIVER	11	5
4400	3	7008 1990 CRITICAL REVIEWS IN IMMUNOLOGY 10(1):1-12 FORDHUTCHINSON AW LEUKOTRIENE-B4 IN INFLAMMATION	238	5

#	Cited nodes	Nodes / Authors	GCS	LCS
4401	8	7089 1990 HEPATOLOGY 12(6):1371-1378 KOLARS JC; MURRAY SA; PETERS KM; WATKINS PB DIFFERENTIAL REGULATION OF LIVER P-450III-CYTOCHROMES IN CHOLINE-DEFICIENT RATS - IMPLICATIONS FOR THE ERYTHROMYCIN BREATH TEST AS A PARAMETER OF LIVER-FUNCTION	13	5
4402	6	7109 1990 JOURNAL OF BIOCHEMICAL TOXICOLOGY 5(3):147-153 LAI TS; CHIANG JYL AFLATOXIN-B1 METABOLISM BY 3-METHYLCHOLANTHRENE-INDUCED HAMSTER HEPATIC CYTOCHROME-P-450S	5	5
4403	5	7110 1990 JOURNAL OF BIOCHEMICAL TOXICOLOGY 5(4):211-219 BEEBE L; PARK SS; ANDERSON LM DIFFERENTIAL ENZYME-INDUCTION OF MOUSE-LIVER AND LUNG FOLLOWING A SINGLE LOW OR HIGH-DOSE OF 2,3,7,8-TETRACHLORODIBENZO-P- DIOXIN (TCDD)	27	5
4404	10	7130 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(8):4348-4353 SUMIMOTO H; MINAKAMI S OXIDATION OF 20-HYDROXYLEUKOTRIENE-B4 TO 20-CARBOXYLEUKOTRIENE- B4 BY HUMAN NEUTROPHIL MICROSOMES - ROLE OF ALDEHYDE DEHYDROGENASE AND LEUKOTRIENE-B4 OMEGA-HYDROXYLASE (CYTOCHROME- P-450LTB-OMEGA) IN LEUKOTRIENE-B4 OMEGA-OXIDATION	23	5
4405	6	7168 1990 JOURNAL OF ENDOCRINOLOGY 126(1):9-16 ANDERSSON T SEX-DIFFERENCES IN CYTOCHROME-P-450-DEPENDENT XENOBIOTIC AND STEROID-METABOLISM IN THE MATURE RAINBOW-TROUT KIDNEY	21	5
4406	6	7169 1990 JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY 138(1-2):49-67 STEGEMAN JJ; RENTON KW; WOODIN BR; ZHANG YS; ADDISON RF EXPERIMENTAL AND ENVIRONMENTAL INDUCTION OF CYTOCHROME-P450E IN FISH FROM BERMUDA WATERS	26	5
4407	5	7193 1990 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 35(5):555-560 LIEHR JG; ROY D; ARIULUBELEN A; BUI QD; WEISZ J; STROBEL HW EFFECT OF CHRONIC ESTROGEN-TREATMENT OF SYRIAN-HAMSTERS ON MICROSOMAL-ENZYMES MEDIATING FORMATION OF CATECHOLESTROGENS AND THEIR REDOX CYCLING - IMPLICATIONS FOR CARCINOGENESIS	29	5
4408	5	7212 1990 METHODS IN ENZYMOLOGY 187():187-195 BRASH AR; HAWKINS DJ HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY FOR CHIRAL ANALYSIS OF EICOSANOIDS	33	5
4409	5	7238 1990 MOLECULAR PHARMACOLOGY 38(1):128-133 WU YR; KAUFFMAN FC; QU W; GANEY P; THURMAN RG UNIQUE ROLE OF OXYGEN IN REGULATION OF HEPATIC MONOOXYGENATION AND GLUCURONIDATION	16	5
4410	5	7257 1990 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 36(2):127-134 SCOTT JG; LEE SST; SHONO T BIOCHEMICAL-CHANGES IN THE CYTOCHROME-P450 MONOOXYGENASES OF 7 INSECTICIDE-RESISTANT HOUSE-FLY (MUSCA-DOMESTICA L) STRAINS	29	5
4411	9	7300 1990 TOXICOLOGY 65(1-2):149-159 MANNING BW; FRANKLIN MR INDUCTION OF RAT UDP-GLUCURONOSYLTRANSFERASE AND GLUTATHIONE-S- TRANSFERASE ACTIVITIES BY L-BUTHIONINE-S,R-SULFOXIMINE WITHOUT INDUCTION OF CYTOCHROME-P-450	15	5
4412	2	7309 1990 TOXICOLOGY IN VITRO 4(4-5):458-460 MOREL F; BEAUNE P; RATANASAVANH D; FLINOIS JP; GUENGERICH FP; GUILLOUZO A EFFECTS OF VARIOUS INDUCERS ON THE EXPRESSION OF CYTOCHROMES-P- 450 CYTOCHROME-IIC8, CYTOCHROME-9, CYTOCHROME-10 AND CYTOCHROME-IIIA IN CULTURED ADULT HUMAN HEPATOCYTES	12	5
4413	3	7315 1990 TRENDS IN PHARMACOLOGICAL SCIENCES 11(9):367-373 PIOMELLI D; GREENGARD P LIPOXYGENASE METABOLITES OF ARACHIDONIC-ACID IN NEURONAL TRANSMEMBRANE SIGNALING	175	5
4414	14	7325 1990 XENOBIOTICA 20(10):1053-1063 HARMSWORTH WL; FRANKLIN MR INDUCTION OF HEPATIC AND EXTRAHEPATIC CYTOCHROME-P-450 AND MONOOXYGENASE ACTIVITIES BY N-SUBSTITUTED IMIDAZOLES	12	5
4415	3	7327 1990 XENOBIOTICA 20(11):1163-1170 TSYRLOV IB; DUZCHAK TG INTERSPECIES FEATURES OF HEPATIC CYTOCHROMES P450-IA1 AND P450- IA2 IN RODENTS	15	5
4416	6	7328 1990 XENOBIOTICA 20(11):1171-1185 PARK BK; KITTERINGHAM NR ASSESSMENT OF ENZYME-INDUCTION AND ENZYME-INHIBITION IN HUMANS - TOXICOLOGICAL IMPLICATIONS	19	5
4417	4	7345 1991 AMERICAN JOURNAL OF HUMAN GENETICS 48(4):799-808 KATSUBE T; SAKAMOTO N; KOBAYASHI Y; SEKI R; HIRANO M; TANISHIMA K; TOMODA A; TAKAZAKURA E; YUBISUI T; TAKESHITA M; SAKAKI Y; FUKUMAKI Y EXONIC POINT MUTATIONS IN NADH-CYTOCHROME-B5 REDUCTASE GENES OF HOMOZYGOTES FOR HEREDITARY METHEMOGLOBINEMIA, TYPE-I AND TYPE- III - PUTATIVE MECHANISMS OF TISSUE-DEPENDENT ENZYME DEFICIENCY	19	5
4418	5	7368 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 289(2):387-392 HAMILTON JW; BEMENT WJ; SINCLAIR PR; SINCLAIR JF; ALCEDO JA; WETTERHAHN KE HEME REGULATES HEPATIC 5-AMINOLEVULINATE SYNTHASE MESSENGER-RNA EXPRESSION BY DECREASING MESSENGER-RNA HALF-LIFE AND NOT BY ALTERING ITS RATE OF TRANSCRIPTION	65	5
4419	20	7382 1991 AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE 21(3):356-362 GEORGE J; FARRELL GC ROLE OF HUMAN HEPATIC CYTOCHROMES-P450 IN DRUG-METABOLISM AND TOXICITY	16	5
4420	3	7391 1991 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 180(3):1187-1193 MUKAI K; IMAI M; SHIMADA H; OKADA Y; OGISHIMA T; ISHIMURA Y STRUCTURAL DIFFERENCES IN 5'-FLANKING REGIONS OF RAT CYTOCHROME-P-450ALDO AND CYTOCHROME-P-45011-BETA GENES	32	5
4421	12	7408 1991 BIOCHEMICAL PHARMACOLOGY 41(9):1299-1309 PAMPORI NA; AGRAWAL AK; WAXMAN DJ; SHAPIRO BH DIFFERENTIAL-EFFECTS OF NEONATALLY ADMINISTERED GLUTAMATE ON THE ULTRADIAN PATTERN OF CIRCULATING GROWTH-HORMONE REGULATING EXPRESSION OF SEX-DEPENDENT FORMS OF CYTOCHROME-P450	31	5
4422	18	7415 1991 BIOCHEMICAL PHARMACOLOGY 42(1):97-101 OMATA Y; FRIEDMAN FK A FLUORESCENCE STUDY OF THE INTERACTIONS OF BENZO[A]PYRENE, CYTOCHROME-P450C AND NADPH CYTOCHROME-P450 REDUCTASE	7	5
4423	18	7435 1991 BIOCHEMISTRY 30(15):3649-3658 STEVENS JC; JAW JY; PENG CT; HALPERT J MECHANISM-BASED INACTIVATION OF BOVINE ADRENAL CYTOCHROME-P450- C-21 AND CYTOCHROME-P450-17-ALPHA BY 17-BETA-SUBSTITUTED STEROIDS	10	5
4424	7	7442 1991 BIOCHEMISTRY 30(42):10287-10294 KIM J; KEMPER B DIFFERENCES IN DEOXYRIBONUCLEASE-I HYPERSENSITIVE SITES IN PHENOBARBITAL-INDUCIBLE AND CONSTITUTIVE RABBIT P450IIC GENES	10	5
4425	3	7455 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1088(3):433-435 GED C; BEAUNE P ISOLATION OF THE HUMAN CYTOCHROME-P-450 IIC8 GENE - MULTIPLE GLUCOCORTICOID RESPONSIVE ELEMENTS IN THE 5' REGION	13	5
4426	7	7490 1991 CARCINOGENESIS 12(5):825-831 MIKALSEN A; ALEXANDER J; WALLIN H; INGELMANSUNDBERG M; ANDERSEN RA REDUCTIVE METABOLISM AND PROTEIN-BINDING OF CHROMIUM(VI) BY P450 PROTEIN ENZYMES	32	5
4427	10	7493 1991 CARCINOGENESIS 12(12):2195-2199 MILES JS; WOLF CR DEVELOPMENTS AND PERSPECTIVES ON THE ROLE OF CYTOCHROME-P450S IN CHEMICAL CARCINOGENESIS	22	5
4428	3	7518 1991 CURRENT EYE RESEARCH 10(8):779-788 SHICHI H; MAHALAK SM; SAKAMOTO S; SUGIYAMA T IMMUNOCYTOCHEMICAL STUDY OF PHENOBARBITAL-INDUCIBLE AND 3- METHYLCHOLANTHRENE-INDUCIBLE CYTOCHROME P450 ISOZYMES IN PRIMARY CULTURES OF PORCINE CILIARY EPITHELIUM	7	5
4429	4	7561 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 200(1):255-261 PERROT N; CHESNE C; DEWAZIERS I; CONNER J; BEAUNE PH; GUILLOUZO A EFFECTS OF ETHANOL AND CLOFIBRATE ON EXPRESSION OF CYTOCHROME- P-450 ENZYMES AND EPOXIDE HYDROLASE IN CULTURES AND COCULTURES OF RAT HEPATOCYTES	22	5
4430	8	7581 1991 FISH PHYSIOLOGY AND BIOCHEMISTRY 9(4):339-349 GOKSOYR A; LARSEN HE THE CYTOCHROME-P450 SYSTEM OF ATLANTIC SALMON (SALMO-SALAR) .1. BASAL PROPERTIES AND INDUCTION OF P450-1A1 IN LIVER OF IMMATURE AND MATURE FISH	25	5
4431	8	7663 1991 JOURNAL OF MEDICAL PRIMATOLOGY 20(7):325-333 SCHULZSCHALGE T; HEGER W; WEBB J; KASTNER M; NEUBERT D ONTOGENY OF MONOOXYGENASE ACTIVITIES IN THE MARMOSET MONKEY (CALLITHRIX-JACCHUS)	8	5
4432	1	7768 1991 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 196(1):8-16 CLEARY MP THE ANTIOBESITY EFFECT OF DEHYDROEPIANDROSTERONE IN RATS	70	5
4433	4	7774 1991 RENAL PHYSIOLOGY AND BIOCHEMISTRY 14(4-5):199-207 ROMERO MF; HOPFER U; MADHUN ZT; ZHOU W; DOUGLAS JG ANGIOTENSIN-II ACTIONS IN THE RABBIT PROXIMAL TUBULE - ANGIOTENSIN-II MEDIATED SIGNALING MECHANISMS AND ELECTROLYTE TRANSPORT IN THE RABBIT PROXIMAL TUBULE	46	5
4434	1	7779 1991 REVUE NEUROLOGIQUE 147(6-7):455-461 KARPATI G; ARNOLD D; MATTHEWS P; CARPENTER S; ANDERMANN F; SHOUBRIDGE E CORRELATIVE MULTIDISCIPLINARY APPROACH TO THE STUDY OF MITOCHONDRIAL ENCEPHALOMYOPATHIES	27	5
4435	14	7842 1992 ANNUAL REVIEW OF MICROBIOLOGY 46():565-601 HARAYAMA S; KOK M; NEIDLE EL FUNCTIONAL AND EVOLUTIONARY RELATIONSHIPS AMONG DIVERSE OXYGENASES	196	5
4436	9	7851 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 292(1):287-294 GOLLY I; HLAVICA P CHEMICAL MODIFICATION OF LYSINE RESIDUES IN CYTOCHROME-P450LM2 (P450IIB4) - INFLUENCE ON HEME LIGANDING OF ARYLAMINES	8	5
4437	4	7854 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 293(1):187-194 KOCHS G; WERCKREICHHART D; GRISEBACH H FURTHER CHARACTERIZATION OF CYTOCHROME-P450 INVOLVED IN PHYTOALEXIN SYNTHESIS IN SOYBEAN - CYTOCHROME-P450 CINNAMATE 4- HYDROXYLASE AND 3,9-DIHYDROXYPTEROCARPAN 6A-HYDROXYLASE	22	5
4438	9	7873 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 297(1):123-131 SALMON F; TATON M; BENVENISTE P; RAHIER A PLANT STEROL BIOSYNTHESIS - NOVEL POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450-DEPENDENT OBTUSIFOLIOL 14-ALPHA- METHYL DEMETHYLASE	18	5
4439	3	7889 1992 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 182(2):974-979 MITSUUCHI Y; KAWAMOTO T; ROSLER A; NAIKI Y; MIYAHARA K; TODA K; KURIBAYASHI I; ORII T; YASUDA K; MIURA K; NAKAO K; IMURA H; ULICK S; SHIZUTA Y CONGENITALLY DEFECTIVE ALDOSTERONE BIOSYNTHESIS IN HUMANS - THE INVOLVEMENT OF POINT MUTATIONS OF THE P-450C18 GENE (CYP11B2) IN CMO II DEFICIENT PATIENTS	31	5
4440	13	7894 1992 BIOCHEMICAL JOURNAL 281():185-190 SEKI K; HIRAI A; NODA M; TAMURA Y; KATO I; YOSHIDA S EPOXYEICOSATRIENOIC ACID STIMULATES ADP-RIBOSYLATION OF A 52- KDA PROTEIN IN RAT-LIVER CYTOSOL	25	5
4441	13	7946 1992 BIOCHEMISTRY INTERNATIONAL 27(6):1073-1081 OHGIYA S; KOMORI M; OHI H; SHIRAMATSU K; SHINRIKI N; KAMATAKI T 6-BASE DELETION OCCURRING IN MESSAGES OF HUMAN CYTOCHROME-P-450 IN THE CYP2C SUBFAMILY RESULTS IN REDUCTION OF TOLBUTAMIDE HYDROXYLASE-ACTIVITY	7	5
4442	2	7972 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1171(1):103-105 OHGIYA S; GODA T; ISHIZAKI K; KAMATAKI T; SHINRIKI N MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF MOUSE NADPH- CYTOCHROME P-450 OXIDOREDUCTASE	8	5
4443	8	7993 1992 CANCER RESEARCH 52(16):4379-4384 LEWIS AD; LAU DHM; DURAN GE; WOLF CR; SIKIC BI ROLE OF CYTOCHROME-P-450 FROM THE HUMAN CYP3A GENE FAMILY IN THE POTENTIATION OF MORPHOLINO DOXORUBICIN BY HUMAN LIVER- MICROSOMES	31	5
4444	4	8026 1992 CLINICAL PHARMACOLOGY & THERAPEUTICS 51(5):507-512 FUNCKBRENTANO C; BOSCO O; JACQZAIGRAIN E; KEUNDJIAN A; JAILLON P RELATION BETWEEN CHLOROGUANIDE BIOACTIVATION TO CYCLOGUANIL AND THE GENETICALLY-DETERMINED METABOLISM OF MEPHENYTOIN IN HUMANS	26	5
4445	7	8040 1992 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 18(3-4):161-168 JACQZAIGRAIN E; CRESTEIL T CYTOCHROME-P450-DEPENDENT METABOLISM OF DEXTROMETHORPHAN - FETAL AND ADULT STUDIES	17	5
4446	8	8042 1992 DNA AND CELL BIOLOGY 11(5):385-395 HORNSBY PJ; YANG LQ; RAJU SG; MAGHSOUDLOU SS; LALA DS; NALLASETH FS DEMETHYLATION OF SPECIFIC SITES IN THE 5'-FLANKING REGION OF THE CYP17-GENES WHEN BOVINE ADRENOCORTICAL-CELLS ARE PLACED IN CULTURE	10	5
4447	13	8056 1992 DRUG METABOLISM AND DISPOSITION 20(5):620-624 KHAN IU; BICKERS DR; HAQQI TM; MUKHTAR H INDUCTION OF CYP1A1 MESSENGER-RNA IN RAT EPIDERMIS AND CULTURED HUMAN EPIDERMAL-KERATINOCYTES BY BENZ(A)ANTHRACENE AND BETA- NAPHTHOFLAVONE	12	5
4448	19	8060 1992 DRUG METABOLISM AND DISPOSITION 20(6):779-791 MOODY DE; GIBSON GG; GRANT DF; MAGDALOU J; RAO MS PEROXISOME PROLIFERATORS, A UNIQUE SET OF DRUG-METABOLIZING ENZYME INDUCERS - COMMENTARY ON A SYMPOSIUM	39	5
4449	5	8067 1992 ENDOCRINOLOGY 131(1):181-186 PANG S; YANG XM; WANG M; TISSOT R; NINO M; MANALIGOD J; BULLOCK LP; MASON JI INHERITED CONGENITAL ADRENAL-HYPERPLASIA IN THE RABBIT - ABSENT CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P450 GENE-EXPRESSION	19	5
4450	5	8071 1992 ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS-PART C OF JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH 10(2):181-203 BUETLER TM; EATON DL GLUTATHIONE S-TRANSFERASES - AMINO-ACID-SEQUENCE COMPARISON, CLASSIFICATION AND PHYLOGENETIC RELATIONSHIP	131	5
4451	7	8079 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 206(3):869-879 HUWYLER J; JEDLITSCHKY G; KEPPLER D; GUT J HALOTHANE METABOLISM - IMPAIRMENT OF HEPATIC OMEGA-OXIDATION OF LEUKOTRIENES INVIVO AND INVITRO	10	5
4452	9	8080 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 206(3):979-986 BELL DR; BARS RG; ELCOMBE CR DIFFERENTIAL TISSUE-SPECIFIC EXPRESSION AND INDUCTION OF CYTOCHROME-P450IVA1 AND ACYL-COA OXIDASE	15	5
4453	12	8112 1992 FEBS LETTERS 310(2):193-196 ORELLANA M; FUENTES O; ROSENBLUTH H; LARA M; VALDES E MODULATION OF RAT-LIVER PEROXISOMAL AND MICROSOMAL FATTY-ACID OXIDATION BY STARVATION	28	5
4454	6	8131 1992 HEPATOLOGY 15(2):276-281 LEE SM; CLEMENS MG EFFECT OF ALPHA-TOCOPHEROL ON HEPATIC MIXED-FUNCTION OXIDASES IN HEPATIC ISCHEMIA REPERFUSION	23	5
4455	4	8132 1992 HEPATOLOGY 15(6):1160-1166 KRAHENBUHL S; STUCKI J; REICHEN J REDUCED ACTIVITY OF THE ELECTRON-TRANSPORT CHAIN IN LIVER- MITOCHONDRIA ISOLATED FROM RATS WITH SECONDARY BILIARY- CIRRHOSIS	47	5
4456	4	8137 1992 HUMAN GENETICS 89(1):95-96 IMAI T; YANASE T; WATERMAN MR; SIMPSON ER; PRATT JJ CANADIAN MENNONITES AND INDIVIDUALS RESIDING IN THE FRIESLAND REGION OF THE NETHERLANDS SHARE THE SAME MOLECULAR-BASIS OF 17- ALPHA-HYDROXYLASE DEFICIENCY	13	5
4457	9	8248 1992 LABORATORY INVESTIGATION 67(5):535-539 KIKKAWA Y DIVERSE ROLE OF PULMONARY CYTOCHROME-P-450 MONOOXYGENASE	22	5
4458	8	8286 1992 MUTATION RESEARCH 269(2):231-236 IMAOKA S; IKEMOTO S; SHIMADA T; FUNAE Y MUTAGENIC ACTIVATION OF AFLATOXIN-B1 BY PULMONARY, RENAL, AND HEPATIC CYTOCHROME-P450S FROM RATS	17	5
4459	23	8298 1992 PHARMACOLOGY & THERAPEUTICS 53(3):275-354 GEBHARDT R METABOLIC ZONATION OF THE LIVER - REGULATION AND IMPLICATIONS FOR LIVER-FUNCTION	147	5
4460	11	8327 1992 TETRAHEDRON LETTERS 33(34):4893-4896 FALCK JR; LUMIN S; LEE SG; HECKMANN B; MIOSKOWSKI C; KARARA A; CAPDEVILA J ENANTIOSPECIFIC SYNTHESIS OF 17-HYDROXYEICOSATETRAENOIC AND 18- HYDROXYEICOSATETRAENOIC ACIDS, CYTOCHROME-P450 ARACHIDONATE METABOLITES	11	5
4461	3	8363 1993 AGE 16(1):1-8 ALTERMAN M; CARVAN M; SRIVASTAVA V; LEAKEY J; HART R; BUSBEE D EFFECTS OF AGING AND LONG-TERM CALORIC RESTRICTION ON HEPATIC- MICROSOMAL MONOOXYGENASES IN FEMALE FISCHER 344 RATS - ALTERATIONS IN BASAL CYTOCHROME-P-450 CATALYTIC ACTIVITIES	9	5
4462	17	8392 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 300(1):391-400 RASHBASTEP J; TURRO NJ; CEDERBAUM AI ESR STUDIES ON THE PRODUCTION OF REACTIVE OXYGEN INTERMEDIATES BY RAT-LIVER MICROSOMES IN THE PRESENCE OF NADPH OR NADH	33	5
4463	9	8396 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 300(1):531-534 DOGRA SC; HAHN CN; MAY BK SUPERINDUCTION BY CYCLOHEXIMIDE OF CYTOCHROME-P4502H1 AND 5- AMINOLEVULINATE SYNTHASE GENE-TRANSCRIPTION IN CHICK-EMBRYO LIVER	16	5
4464	11	8402 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 303(2):313-320 BLOUIN RA; BANDYOPADHYAY AM; CHAUDHARY I; ROBERTSON LW; GEMZIK B; PARKINSON A CYTOCHROME-P450-2B ENZYME (CYP2B) INDUCTION DEFECT FOLLOWING PHENOBARBITAL TREATMENT IN THE FA/FA ZUCKER RAT - MOLECULAR CHARACTERIZATION	21	5
4465	5	8454 1993 BIOCHEMICAL PHARMACOLOGY 45(4):833-839 KERRY NL; SOMOGYI AA; MIKUS G; BOCHNER F PRIMARY AND SECONDARY OXIDATIVE-METABOLISM OF DEXTROMETHORPHAN - INVITRO STUDIES WITH FEMALE SPRAGUE-DAWLEY AND DARK AGOUTI RAT-LIVER MICROSOMES	24	5
4466	12	8472 1993 BIOCHEMICAL PHARMACOLOGY 46(3):413-419 WANG RS; NAKAJIMA T; PARK SS; GELBOIN HV; MURAYAMA N MONOCLONAL ANTIBODY-DIRECTED ASSESSMENT OF TOLUENE INDUCTION OF RAT HEPATIC CYTOCHROME-P450 ISOZYMES	18	5
4467	15	8479 1993 BIOCHEMICAL PHARMACOLOGY 46(10):1781-1790 VANTKLOOSTER GAE; BLAAUBOER BJ; NOORDHOEK J; VANMIERT ASJPAM CYTOCHROME-P450 INDUCTION AND METABOLISM OF ALKOXYRESORUFINS, ETHYLMORPHINE AND TESTOSTERONE IN CULTURED-HEPATOCYTES FROM GOATS, SHEEP AND CATTLE	26	5
4468	12	8509 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1161(1):38-46 EDWARDS RJ; MURRAY BP; MURRAY S; SINGLETON AM; DAVIES DS; BOOBIS AR AN INHIBITORY MONOCLONAL ANTIPROTEIN ANTIBODY AND AN ANTIPEPTIDE ANTIBODY SHARE AN EPITOPE ON RAT CYTOCHROME-P-450 ENZYMES CYP1A1 AND CYP1A2	11	5
4469	6	8516 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1172(1-2):124-130 MARIE S; ROUSSEL F; CRESTEIL T AGE-DEPENDENT AND TISSUE-DEPENDENT EXPRESSION OF CYP2C23 IN THE RAT	11	5
4470	13	8538 1993 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 71(2):151-156 MCCALLUM GP; HORTON JE; FALKNER KC; BEND JR MICROSOMAL CYTOCHROME-P450 1A1 DEPENDENT MONOOXYGENASE ACTIVITY IN GUINEA-PIG HEART - INDUCTION, INHIBITION, AND INCREASED ACTIVITY BY ADDITION OF EXOGENOUS NADPH CYTOCHROME-P450 REDUCTASE	15	5
4471	8	8575 1993 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 104(1):61-65 ARINC E; SEN A EFFECTS OF INVIVO BENZENE TREATMENT ON CYTOCHROME-P450 AND MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS- AURATA) LIVER-MICROSOMES	9	5
4472	15	8576 1993 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 104(3):433-437 ANTIGNAC E; FUKUHARA M; KIMURA M EFFECTS OF DEXAMETHASONE ON THE HEPATIC CYTOCHROME-P(450) IIIA SUBFAMILY IN 2 HAMSTER STRAINS MESOCRICETUS-AURATUS AND CRICETUS GRISEUS	11	5
4473	17	8587 1993 DRUG METABOLISM AND DISPOSITION 21(1):56-61 ROBERTS EA; XIE ZW; YANG S; LIPA J INDUCIBILITY OF ENZYME-ACTIVITIES ASSOCIATED WITH THE CYTOCHROME-P-450 1A FAMILY, ETHOXYRESORUFIN O-DETHYLASE, AND METHOXYRESORUFIN O-DEMETHYLASE IN HUMAN HEPATOCYTE LINES DERIVED FROM NORMAL LIVER-TISSUE	24	5
4474	14	8597 1993 DRUG METABOLISM REVIEWS 25(1-2):1-48 HANSCH C; ZHANG LT QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS OF CYTOCHROME-P- 450	31	5
4475	19	8611 1993 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 12(6):989-999 VANDERWEIDEN MEJ; CELANDER M; SEINEN W; VANDENBERG M; GOKSOYR A; FORLIN L INDUCTION OF CYTOCHROME-P450 1A IN FISH TREATED WITH 2,3,7,8- TETRACHLORODIBENZO-P-DIOXIN OR CHEMICALLY CONTAMINATED SEDIMENT	25	5
4476	6	8615 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 213(2):683-687 MCKNIGHT J; CHEESMAN MR; THOMSON AJ; MILES JS; MUNRO AW IDENTIFICATION OF CHARGE-TRANSFER TRANSITIONS IN THE OPTICAL- SPECTRUM OF LOW-SPIN FERRIC CYTOCHROME-P-450 BACILLUS- MEGATERIUM	20	5
4477	15	8666 1993 JOURNAL OF BACTERIOLOGY 175(18):6028-6037 ROPP JD; GUNSALUS IC; SLIGAR SG CLONING AND EXPRESSION OF A MEMBER OF A NEW CYTOCHROME-P-450 FAMILY - CYTOCHROME P-450LIN (CYP111) FROM PSEUDOMONAS- INCOGNITA	10	5
4478	11	8669 1993 JOURNAL OF BIOCHEMISTRY 113(2):144-152 NOMURA M; MOROHASHI K; KIRITA S; NONAKA Y; OKAMOTO M; NAWATA H; OMURA T 3 FORMS OF RAT CYP11B GENES - 11 BETA-HYDROXYLASE GENE, ALDOSTERONE SYNTHASE GENE, AND A NOVEL GENE	43	5
4479	9	8673 1993 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 25(4):367-375 VINOGRADOV AD KINETICS, CONTROL, AND MECHANISM OF UBIQUINONE REDUCTION BY THE MAMMALIAN RESPIRATORY CHAIN-LINKED NADH-UBIQUINONE REDUCTASE	52	5
4480	3	8685 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9430-9436 WOLFF DJ; DATTO GA; SAMATOVICZ RA THE DUAL-MODE OF INHIBITION OF CALMODULIN-DEPENDENT NITRIC- OXIDE SYNTHASE BY ANTIFUNGAL IMIDAZOLE AGENTS	49	5
4481	2	8687 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(16):11639-11654 PASCAL S; TATON M; RAHIER A PLANT STEROL BIOSYNTHESIS - IDENTIFICATION AND CHARACTERIZATION OF 2 DISTINCT MICROSOMAL OXIDATIVE ENZYMATIC SYSTEMS INVOLVED IN STEROL C4-DEMETHYLATION	26	5
4482	12	8708 1993 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 76(6):1555-1559 VANVOORHIS BJ; DUNN MS; FALCK JR; BHATT RK; VANROLLINS M; SNYDER GD METABOLISM OF ARACHIDONIC-ACID TO EPOXYEICOSATRIENOIC ACIDS BY HUMAN GRANULOSA-CELLS MAY MEDIATE STEROIDOGENESIS	16	5
4483	1	8748 1993 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115(19):8775-8779 HARRIS D; LOEW G DETERMINANTS OF THE SPIN-STATE OF THE RESTING STATE OF CYTOCHROME-P450CAM	41	5
4484	3	8875 1993 XENOBIOTICA 23(1):79-96 LEWIS DFV; LAKE BG INTERACTION OF SOME PEROXISOME PROLIFERATORS WITH THE MOUSE- LIVER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR (PPAR) - A MOLECULAR MODELING AND QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP (QSAR) STUDY	28	5
4485	35	8899 1994 ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 29 29():307-316 MINERS JO; VERONESE ME; BIRKETT DJ IN-VITRO APPROACHES FOR THE PREDICTION OF HUMAN DRUG-METABOLISM	24	5
4486	15	8906 1994 AQUATIC TOXICOLOGY 29(3-4):183-196 CELANDER M; NAF C; BROMAN D; FORLIN L TEMPORAL ASPECTS OF INDUCTION OF HEPATIC CYTOCHROME-P450 1A AND CONJUGATING ENZYMES IN THE VIVIPAROUS BLENNY (ZOARCES- VIVIPARUS) TREATED WITH PETROLEUM-HYDROCARBONS	24	5
4487	2	8929 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):273-278 WANG LH; TAZAWA R; LANG AQ; WU KK ALTERNATE SPLICING OF HUMAN THROMBOXANE SYNTHASE MESSENGER-RNA	15	5
4488	6	8938 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 198(2):795-803 PINOT F; ALAYRAC C; MIOSKOWSKI C; DURST F; SALAUN JP NEW CYTOCHROME P450-DEPENDENT REACTIONS FROM WHEAT - TERMINAL AND SUB-TERMINAL HYDROXYLATION OF OLEIC-ACID BY MICROSOMES FROM NAPHTHALIC ACID ANHYDRIDE AND PHENOBARBITAL INDUCED WHEAT SEEDLINGS	12	5
4489	3	8946 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 202(1):586-590 NAKAYAMA N; SHOUN H FATTY-ACID HYDROXYLASE OF THE FUNGUS FUSARIUM-OXYSPORUM IS POSSIBLY A FUSED PROTEIN OF CYTOCHROME-P-450 AND ITS REDUCTASE	9	5
4490	15	8962 1994 BIOCHEMICAL PHARMACOLOGY 47(4):727-735 SHIRAGA T; MATSUDA H; NAGASE K; IWASAKI K; NODA K; YAMAZAKI H; SHIMADA T; FUNAE Y METABOLISM OF FK506, A POTENT IMMUNOSUPPRESSIVE AGENT, BY CYTOCHROME-P450 3A ENZYMES IN RAT, DOG AND HUMAN LIVER- MICROSOMES	38	5
4491	15	8964 1994 BIOCHEMICAL PHARMACOLOGY 47(5):893-903 HAASCH ML; GRAF WK; QUARDOKUS EM; MAYER RT; LECH JJ USE OF 7-ALKOXYPHENOXAZONES, 7-ALKOXYCOUMARINS AND 7- ALKOXYQUINOLINES AS FLUORESCENT SUBSTRATES FOR RAINBOW-TROUT HEPATIC MICROSOMES AFTER TREATMENT WITH VARIOUS INDUCERS	16	5
4492	9	8966 1994 BIOCHEMICAL PHARMACOLOGY 47(7):1221-1229 PAMPORI NA; SHAPIRO BH EFFECTS OF NEONATALLY ADMINISTERED MONOSODIUM GLUTAMATE ON THE SEXUALLY DIMORPHIC PROFILES OF CIRCULATING GROWTH-HORMONE REGULATING MURINE HEPATIC MONOOXYGENASES	13	5
4493	16	8984 1994 BIOCHEMISTRY 33(3):807-817 MILLER JP; WHITE RE PHOTOAFFINITY-LABELING OF CYTOCHROME-P450-2B4 - CAPTURE OF ACTIVE-SITE HEME LIGANDS BY A PHOTOCARBENE	12	5
4494	10	8992 1994 BIOCHEMISTRY 33(22):6945-6951 BLACK SD; MARTIN ST; SMITH CA MEMBRANE TOPOLOGY OF LIVER MICROSOMAL CYTOCHROME-P450 2B4 DETERMINED VIA MONOCLONAL-ANTIBODIES DIRECTED TO THE HALT- TRANSFER SIGNAL	19	5
4495	5	9012 1994 BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 1212(1):1-25 SERHAN CN LIPOXIN BIOSYNTHESIS AND ITS IMPACT IN INFLAMMATORY AND VASCULAR EVENTS	104	5
4496	17	9015 1994 BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY 1207(2):179-186 SEQUEIRA DJ; CAWLEY GF; EYER CS; BACKES WL TEMPORAL CHANGES IN P-450 2E1 EXPRESSION WITH CONTINUED ETHYLBENZENE EXPOSURE	9	5
4497	16	9017 1994 BIOLOGICAL & PHARMACEUTICAL BULLETIN 17(1):22-28 SHIRAGA T; IWASAKI K; NOZAKI K; TAMURA T; YAMAZOE Y; KATO R; TAKANAKA A ISOLATION AND CHARACTERIZATION OF 4 CYTOCHROME-P450 ISOZYMES FROM UNTREATED AND PHENOBARBITAL-TREATED BEAGLE DOGS	13	5
4498	6	9045 1994 CELL 78(6):927-930 MARLETTA MA NITRIC-OXIDE SYNTHASE - ASPECTS CONCERNING STRUCTURE AND CATALYSIS	392	5
4499	4	9056 1994 CLINICAL PHARMACOKINETICS 26(3):201-214 ALTAMURA AC; MORO AR; PERCUDANI M CLINICAL PHARMACOKINETICS OF FLUOXETINE	92	5
4500	11	9076 1994 DNA AND CELL BIOLOGY 13(8):781-792 JEAN A; REISS A; DESROCHERS M; DUBOIS S; TROTTIER E; TROTTIER Y; WIRTANEN L; ADESNIK M; WAXMAN DJ; ANDERSON A RAT-LIVER CYTOCHROME-P450 2B3 - STRUCTURE OF THE CYP2B3 GENE AND IMMUNOLOGICAL IDENTIFICATION OF A CONSTITUTIVE P450 2B3- LIKE PROTEIN IN RAT-LIVER	14	5

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