#	Cited nodes	Nodes / Authors	GCS	LCS
3601	27	7800 1991 XENOBIOTICA 21(1):121-135 BLANCK J; RISTAU O; ZHUKOV AA; ARCHAKOV AI; REIN H; RUCKPAUL K CYTOCHROME-P-450 SPIN STATE AND LEAKINESS OF THE MONOOXYGENASE PATHWAY	9	7
3602	7	7832 1992 AMERICAN JOURNAL OF PHYSIOLOGY 263(2):G215-G223 TRABER PG; WEI W; LAI Y DIFFERENTIAL REGULATION OF CYTOCHROME-P-450 GENES ALONG RAT INTESTINAL CRYPT-VILLUS AXIS	17	7
3603	14	7837 1992 ANALYTICAL BIOCHEMISTRY 207(2):236-240 CAPDEVILA JH; WEI SZ; KUMAR A; KOBAYASHI J; SNAPPER JR; ZELDIN DC; BHATT RK; FALCK JR RESOLUTION OF DIHYDROXYEICOSANOATES AND OF DIHYDROXYEICOSATRIENOATES BY CHIRAL PHASE CHROMATOGRAPHY	12	7
3604	12	7878 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(1):198-203 KRAINEV AG; SHIMIZU T; HIROYA K; HATANO M EFFECT OF MUTATIONS AT LYS250, ARG251, AND LYS253 OF CYTOCHROME-P450-1A2 ON THE CATALYTIC ACTIVITIES AND THE BINDINGS OF BIFUNCTIONAL AXIAL LIGANDS	16	7
3605	7	7884 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 299(1):110-115 PAN JM; HONG JY; YANG CS POSTTRANSCRIPTIONAL REGULATION OF MOUSE RENAL CYTOCHROME-P450 2E1 BY TESTOSTERONE	19	7
3606	6	7890 1992 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 184(1):471-477 TAKAGI Y; OGAWA H; HARADA N; SHIMADA H; ISHIMURA Y; TAKAGI Y EXPRESSION AND TRANSPORT INTO MITOCHONDRIA OF BOVINE CYTOCHROME P-450(SCC) IN INSECT CELLS USING THE BACULOVIRUS EXPRESSION SYSTEM	13	7
3607	11	7902 1992 BIOCHEMICAL JOURNAL 287():775-783 FRIEDBERG T; GRASSOW MA; BARTLOMOWICZOESCH B; SIEGERT P; ARAND M; ADESNIK M; OESCH F SEQUENCE OF A NOVEL CYTOCHROME CYP2B CDNA CODING FOR A PROTEIN WHICH IS EXPRESSED IN A SEBACEOUS GLAND, BUT NOT IN THE LIVER	12	7
3608	11	7915 1992 BIOCHEMICAL PHARMACOLOGY 43(10):2065-2071 MURRAY M; FIELD SL INHIBITION AND METABOLITE COMPLEXATION OF RAT HEPATIC- MICROSOMAL CYTOCHROME-P450 BY TRICYCLIC ANTIDEPRESSANTS	24	7
3609	9	7919 1992 BIOCHEMICAL PHARMACOLOGY 43(12):2535-2542 YOO JSH; SMITH TJ; NING SM; LEE MJ; THOMAS PE; YANG CS MODULATION OF THE LEVELS OF CYTOCHROMES-P450 IN RAT-LIVER AND LUNG BY DIETARY-LIPID	32	7
3610	3	7951 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1098(2):144-150 KOTLYAR AB; SLED VD; VINOGRADOV AD EFFECT OF CA2+ IONS ON THE SLOW ACTIVE INACTIVE TRANSITION OF THE MITOCHONDRIAL NADH-UBIQUINONE REDUCTASE	27	7
3611	17	7957 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1122(1):6-14 HONKAKOSKI P; LINNALAKANKKUNEN A; USANOV SA; LANG MA HIGHLY HOMOLOGOUS CYTOCHROME-P-450 AND CYTOCHROME-B5 - A MODEL TO STUDY PROTEIN PROTEIN INTERACTIONS IN A RECONSTITUTED MONOOXYGENASE SYSTEM	13	7
3612	8	8057 1992 DRUG METABOLISM AND DISPOSITION 20(5):726-729 FRANKLIN MR; MOODY DE CONCOMITANT INDUCTION OF MICROSOMAL EPOXIDE HYDROLASE AND UDPGLUCURONOSYLTRANSFERASE ACTIVITIES BY DIPYRIDINE COMPOUNDS	14	7
3613	5	8059 1992 DRUG METABOLISM AND DISPOSITION 20(5):770-772 RUZICKA JA; RUENITZ PC CYTOCHROME-P-450-MEDIATED N-DECHLOROETHYLATION OF CYCLOPHOSPHAMIDE AND IFOSFAMIDE IN THE RAT	25	7
3614	5	8085 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 210(3):741-746 VOZNESENSKY AI; SCHENKMAN JB INHIBITION OF CYTOCHROME-P450 REDUCTASE BY POLYOLS HAS AN ELECTROSTATIC NATURE	18	7
3615	4	8092 1992 EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY 44(7):399-405 BARTH A; BERNST M INFLUENCE OF BILE-ACIDS ON STIMULATED LIPID-PEROXIDATION AND HYDROGEN-PEROXIDE PRODUCTION IN RAT-LIVER MICROSOMES	16	7
3616	8	8117 1992 FOOD AND CHEMICAL TOXICOLOGY 30(7):589-599 WORTELBOER HM; VANDERLINDEN ECM; DEKRUIF CA; NOORDHOEK J; BLAAUBOER BJ; VANBLADEREN PJ; FALKE HE EFFECTS OF INDOLE-3-CARBINOL ON BIOTRANSFORMATION ENZYMES IN THE RAT - INVIVO CHANGES IN LIVER AND SMALL INTESTINAL-MUCOSA IN COMPARISON WITH PRIMARY HEPATOCYTE CULTURES	53	7
3617	4	8152 1992 JOURNAL OF BIOCHEMISTRY 112(5):573-575 HASHIMOTO T; MOROHASHI K; TAKAYAMA K; HONDA S; WADA T; HANDA H; OMURA T COOPERATIVE TRANSCRIPTION ACTIVATION BETWEEN AD1, A CRE-LIKE ELEMENT, AND OTHER ELEMENTS IN THE CYP11B GENE PROMOTER	20	7
3618	9	8225 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 263(3):1471-1478 BOULENC X; BOURRIE M; FABRE I; ROQUE C; JOYEUX H; BERGER Y; FABRE G REGULATION OF CYTOCHROME-P450IA1 GENE-EXPRESSION IN A HUMAN INTESTINAL-CELL LINE, CACO-2	39	7
3619	3	8253 1992 LIPIDS 27(7):487-493 HAMBERG M; GERWICK WH; ASEN PA LINOLEIC-ACID METABOLISM IN THE RED ALGA LITHOTHAMNION- CORALLIOIDES - BIOSYNTHESIS OF 11(R)-HYDROXY-9(Z), 12(Z)- OCTADECADIENOIC ACID	29	7
3620	6	8328 1992 TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 168(2):67-72 GONZALEZ FJ; CRESPI CL; CZERWINSKI M; GELBOIN HV ANALYSIS OF HUMAN CYTOCHROME-P450 CATALYTIC ACTIVITIES AND EXPRESSION	11	7
3621	7	8438 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 197(2):599-605 PADGHAM CRW; BOYLE CC; WANG XJ; RALEIGH SM; WRIGHT MC; PAINE AJ ALTERATION OF TRANSCRIPTION FACTOR MESSENGER-RNAS DURING THE ISOLATION AND CULTURE OF RAT HEPATOCYTES SUGGESTS THE ACTIVATION OF A PROLIFERATIVE MODE UNDERLIES THEIR DEDIFFERENTIATION	33	7
3622	5	8531 1993 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 35(1):30-34 WU D; OTTON SV; SPROULE BA; BUSTO U; INABA T; KALOW W; SELLERS EM INHIBITION OF HUMAN CYTOCHROME P450 2D6 (CYP2D6) BY METHADONE	46	7
3623	15	8552 1993 CARCINOGENESIS 14(7):1421-1427 TIANO HF; HOSOKAWA M; CHULADA PC; SMITH PB; WANG RL; GONZALEZ FJ; CRESPI CL; LANGENBACH R RETROVIRAL-MEDIATED EXPRESSION OF HUMAN CYTOCHROME-P450-2A6 IN C3H/10T1/2 CELLS CONFERS TRANSFORMABILITY BY 4- (METHYLNITROSAMINO)-1-(3-PYRIDYL)-1-BUTANONE (NNK)	24	7
3624	2	8579 1993 CURRENT BIOLOGY 3(10):668-674 LANCET D; BENARIE N OLFACTORY RECEPTORS	113	7
3625	8	8589 1993 DRUG METABOLISM AND DISPOSITION 21(2):358-363 OHMORI S; ISHII I; KURIYA SI; TANIGUCHI T; RIKIHISA T; HIROSE S; KANAKUBO Y; KITADA M EFFECTS OF CLARITHROMYCIN AND ITS METABOLITES ON THE MIXED- FUNCTION OXIDASE SYSTEM IN HEPATIC MICROSOMES OF RATS	20	7
3626	34	8617 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 218(2):355-361 PEYRONNEAU MA; RENAUD JP; JAOUEN M; URBAN P; CULLIN C; POMPON D; MANSUY D EXPRESSION IN YEAST OF 3 ALLELIC CDNAS CODING FOR HUMAN LIVER P-450 3A4 - DIFFERENT STABILITIES, BINDING-PROPERTIES AND CATALYTIC ACTIVITIES OF THE YEAST-PRODUCED ENZYMES	13	7
3627	9	8636 1993 FUNDAMENTAL & CLINICAL PHARMACOLOGY 7(2):69-75 SEREE EJ; PISANO PJ; PLACIDI M; RAHMANI R; BARRA YA IDENTIFICATION OF THE HUMAN AND ANIMAL HEPATIC CYTOCHROMES-P450 INVOLVED IN CLONAZEPAM METABOLISM	20	7
3628	4	8675 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(2):1053-1057 PASCO DS; BOYUM KW; ELBI C; SIU CS; FAGAN JB INDUCER-DEPENDENT TRANSCRIPTIONAL ACTIVATION OF THE P4501A2 GENE INVIVO AND IN ISOLATED HEPATOCYTES	18	7
3629	10	8683 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(12):9130-9137 MUKAI K; IMAI M; SHIMADA H; ISHIMURA Y ISOLATION AND CHARACTERIZATION OF RAT CYP11B GENES INVOLVED IN LATE STEPS OF MINERALOCORTICOID AND GLUCOCORTICOID SYNTHESES	50	7
3630	16	8706 1993 JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY 57(3):195-211 LIVINGSTONE DR BIOTECHNOLOGY AND POLLUTION MONITORING - USE OF MOLECULAR BIOMARKERS IN THE AQUATIC ENVIRONMENT	129	7
3631	17	8736 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):927-936 KIM HS; PUTT D; REDDY S; HOLLENBERG PF; NOVAK RF ENHANCED EXPRESSION OF RAT HEPATIC CYP2B1/2B2 AND 2E1 BY PYRIDINE - DIFFERENTIAL INDUCTION KINETICS AND MOLECULAR-BASIS OF EXPRESSION	29	7
3632	12	8781 1993 MOLECULAR PHARMACOLOGY 43(4):504-508 QUATTROCHI LC; TUKEY RH NUCLEAR UPTAKE OF THE AH (DIOXIN) RECEPTOR IN RESPONSE TO OMEPRAZOLE - TRANSCRIPTIONAL ACTIVATION OF THE HUMAN CYP1A1 GENE	43	7
3633	12	8799 1993 PHARMACOGENETICS 3(2):77-85 CHEN LS; YASUMORI T; YAMAZOE Y; KATO R HEPATIC-MICROSOMAL TOLBUTAMIDE HYDROXYLATION IN JAPANESE - INVITRO EVIDENCE FOR RAPID AND SLOW METABOLIZERS	13	7
3634	9	8800 1993 PHARMACOGENETICS 3(3):123-130 BROLY F; MEYER UA DEBRISOQUINE OXIDATION POLYMORPHISM - PHENOTYPIC CONSEQUENCES OF A 3-BASE-PAIR DELETION IN EXON 5 OF THE CYP2D6 GENE	35	7
3635	2	8822 1993 PHYTOCHEMISTRY 32(3):653-657 CLEMENS S; HINDERER W; WITTKAMPF U; BARZ W CHARACTERIZATION OF CYTOCHROME P450-DEPENDENT ISOFLAVONE HYDROXYLASES FROM CHICKPEA	20	7
3636	21	8843 1993 STEROIDS 58(12):573-579 MCGIFF JC; QUILLEY CP; CARROLL MA THE CONTRIBUTION OF CYTOCHROME P450-DEPENDENT ARACHIDONATE METABOLITES TO INTEGRATED RENAL-FUNCTION	17	7
3637	2	8847 1993 THERAPEUTIC DRUG MONITORING 15(3):258-260 BROSEN K; KRAGHSORENSEN P CONCOMITANT INTAKE OF NORTRIPTYLINE AND CARBAMAZEPINE	29	7
3638	15	8858 1993 TOXICOLOGY 82(1-3):77-88 GONZALEZ FJ MOLECULAR-BIOLOGY OF HUMAN XENOBIOTIC-METABOLIZING CYTOCHROMES- P450 - ROLE OF VACCINIA VIRUS CDNA EXPRESSION IN EVALUATING CATALYTIC FUNCTION	8	7
3639	11	8861 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 118(2):255-262 POSTLIND H; VU TP; TUKEY RH; QUATTROCHI LC RESPONSE OF HUMAN CYP1-LUCIFERASE PLASMIDS TO 2,3,7,8- TETRACHLORODIBENZO-P-DIOXIN AND POLYCYCLIC AROMATIC- HYDROCARBONS	64	7
3640	22	8862 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 119(1):66-73 UENG TH; UENG YF; CHEN TL; PARK SS; IWASAKI M; GUENGERICH FP INDUCTION OF CYTOCHROME-P450-DEPENDENT MONOOXYGENASES IN HAMSTER TISSUES BY FASTING	28	7
3641	5	8880 1993 XENOBIOTICA 23(4):419-426 OHMORI S; TANIGUCHI T; RIKIHISA T; KANAKUBO Y; KITADA M SPECIES-DIFFERENCES OF TESTOSTERONE 16-HYDROXYLASES IN LIVER- MICROSOMES OF GUINEA-PIG, RAT AND DOG	18	7
3642	12	8904 1994 AQUATIC TOXICOLOGY 28(3-4):147-167 LINDSTROMSEPPA P; KORYTKO PJ; HAHN ME; STEGEMAN JJ UPTAKE OF WATERBORNE 3,3',4,4'-TETRACHLOROBIPHENYL AND ORGAN AND CELL-SPECIFIC INDUCTION OF CYTOCHROME P4501A IN ADULT AND LARVAL FATHEAD MINNOW PIMEPHALES-PROMELAS	25	7
3643	18	8915 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):397-401 HIROYA K; MURAKAMI Y; SHIMIZU T; HATANO M; DEMONTELLANO PRO DIFFERENTIAL ROLES OF GLU318 AND THR319 IN CYTOCHROME-P450-1A2 CATALYSIS SUPPORTED BY NADPH-CYTOCHROME-P450 REDUCTASE AND TERT-BUTYL HYDROPEROXIDE	16	7
3644	11	8918 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):395-401 OHMORI S; CHIBA K; NAKASA H; HORIE T; KITADA M CHARACTERIZATION OF MONKEY CYTOCHROME-P450, P450-CMLD, RESPONSIBLE FOR S-MEPHENYTOIN 4'-HYDROXYLATION IN HEPATIC MICROSOMES OF CYNOMOLGUS MONKEYS	17	7
3645	14	8930 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 315(2):438-444 YANG MX; CEDERBAUM AI FRACTIONATION OF LIVER-MICROSOMES WITH POLYETHYLENE-GLYCOL AND PURIFICATION OF NADH-CYTOCHROME B(5) OXIDOREDUCTASE AND CYTOCHROME B(5)	14	7
3646	8	8972 1994 BIOCHEMICAL PHARMACOLOGY 48(1):197-200 RODRIGUES AD COMPARISON OF LEVELS OF ALDEHYDE OXIDASE WITH CYTOCHROME-P450 ACTIVITIES IN HUMAN LIVER IN-VITRO	20	7
3647	16	8977 1994 BIOCHEMICAL PHARMACOLOGY 48(7):1363-1369 MAENPAA J; JUVONEN R; RAUNIO H; RAUTIO A; PELKONEN O METABOLIC INTERACTIONS OF METHOXSALEN AND COUMARIN IN HUMANS AND MICE	30	7
3648	8	9009 1994 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1201(2):245-250 KLEIN ML; FULCO AJ THE INTERACTION OF CYTOCHROME-C AND THE HEME DOMAIN OF CYTOCHROME P-450(BM-3) WITH THE REDUCTASE DOMAIN OF CYTOCHROME P-450(BM-3)	7	7
3649	8	9032 1994 CANCER RESEARCH 54(7):S1982-S1986 YANG CS; SMITH TJ; HONG JY CYTOCHROME-P-450 ENZYMES AS TARGETS FOR CHEMOPREVENTION AGAINST CHEMICAL CARCINOGENESIS AND TOXICITY - OPPORTUNITIES AND LIMITATIONS	100	7
3650	5	9039 1994 CARCINOGENESIS 15(5):933-937 THOMSEN JS; WANG X; HINES RN; SAFE S RESTORATION OF ARYL-HYDROCARBON (AH) RESPONSIVENESS IN MDA-MB- 231 HUMAN BREAST-CANCER CELLS BY TRANSIENT EXPRESSION OF THE ESTROGEN-RECEPTOR	43	7
3651	9	9042 1994 CARCINOGENESIS 15(9):1955-1961 ROMKESSPARKS M; MNUSKIN A; CHERN HD; PERSAD R; FLEMING C; SIBLEY GNA; SMITH P; WILKINSON GR; BRANCH RA CORRELATION OF POLYMORPHIC EXPRESSION OF CYP2D6 MESSENGER-RNA IN BLADDER MUCOSA AND TUMOR-TISSUE TO IN-VIVO DEBRISOQUINE HYDROXYLASE-ACTIVITY	15	7
3652	7	9078 1994 DNA AND CELL BIOLOGY 13(8):805-819 STROM A; EGUCHI H; MODE A; LEGRAVEREND C; TOLLET P; STROMSTEDT PE; GUSTAFSSON JA CHARACTERIZATION OF THE PROXIMAL PROMOTER AND 2 SILENCER ELEMENTS IN THE CYP2C11 GENE EXPRESSED IN RAT-LIVER	26	7
3653	4	9151 1994 GENE 146(2):221-226 REIMMANN C; VANETTEN HD CLONING AND CHARACTERIZATION OF THE PDA6-1 GENE ENCODING A FUNGAL CYTOCHROME-P-450 WHICH DETOXIFIES THE PHYTOALEXIN PISATIN FROM GARDEN PEA	18	7
3654	6	9153 1994 GENERAL AND COMPARATIVE ENDOCRINOLOGY 95(2):155-168 TRANT JM ISOLATION AND CHARACTERIZATION OF THE CDNA-ENCODING THE CHANNEL CATFISH (ICTALURUS-PUNCTATUS) FORM OF CYTOCHROME P450AROM	38	7
3655	10	9156 1994 GUT 35(5):599-603 MURRAY GI; SHAW D; WEAVER RJ; MCKAY JA; EWEN SWB; MELVIN WT; BURKE MD CYTOCHROME-P450 EXPRESSION IN ESOPHAGEAL CANCER	31	7
3656	23	9164 1994 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 26(10-11):1261-1268 SHIMOJO N CYTOCHROME-P450 CHANGES IN RATS WITH STREPTOZOCIN-INDUCED DIABETES	14	7
3657	7	9180 1994 JOURNAL OF BIOCHEMISTRY 116(4):801-810 SAGAMI I; KIKUCHI H; IKAWA S; WATANABE M CHARACTERIZATION OF HAMSTER CYP1A1 GENE - INDUCIBLE EXPRESSION AND NEGATIVE REGULATION	10	7
3658	13	9232 1994 JOURNAL OF LIPID RESEARCH 35(7):1222-1231 KARAM WG; CHIANG JYL EXPRESSION AND PURIFICATION OF HUMAN CHOLESTEROL 7-ALPHA- HYDROXYLASE IN ESCHERICHIA-COLI	18	7
3659	6	9270 1994 JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (24):2761-2762 FOWLER SM; ENGLAND PA; WESTLAKE ACG; ROUCH DR; NICKERSON DP; BLUNT C; BRAYBROOK D; WEST S; WONG LL; FLITSCH SL CYTOCHROME P-450(CAM) MONOOXYGENASE CAN BE REDESIGNED TO CATALYZE THE REGIOSELECTIVE AROMATIC HYDROXYLATION OF DIPHENYLMETHANE	16	7
3660	11	9331 1994 PHARMACOGENETICS 4(6):323-331 YASUMORI T; LI QH; YAMAZOE Y; UEDA M; TSUZUKI T; KATO R LACK OF LOW K-M DIAZEPAM N-DEMETHYLASE IN LIVERS OF POOR METABOLIZERS FOR S-MEPHENYTOIN 4'-HYDROXYLATION	21	7
3661	44	9386 1994 VITAMINS AND HORMONES, VOL 49 49():131-195 WHITE PC GENETIC-DISEASES OF STEROID-METABOLISM	27	7
3662	4	9417 1995 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 61(3):883-889 USUDA K; TORITSUKA N; MATSUO Y; KIM DH; SHOUN H DENITRIFICATION BY THE FUNGUS CYLINDROCARPON-TONKINENSE - ANAEROBIC CELL-GROWTH AND 2 ISOZYME FORMS OF CYTOCHROME P- 450NOR	34	7
3663	18	9499 1995 BIOCHEMICAL PHARMACOLOGY 50(7):895-903 MURRAY GI; BURKE MD IMMUNOHISTOCHEMISTRY OF DRUG-METABOLIZING-ENZYMES	31	7
3664	8	9514 1995 BIOCHEMISTRY 34(35):11221-11226 GOVINDARAJ S; POULOS TL ROLE OF THE LINKER REGION CONNECTING THE REDUCTASE AND HEME DOMAINS IN CYTOCHROME P450(BM-3)	14	7
3665	23	9533 1995 BIOCHIMIE 77(7-8):581-593 DEMONTELLANO PRO ARYLHYDRAZINES AS PROBES OF HEMOPROTEIN STRUCTURE AND FUNCTION	23	7
3666	3	9582 1995 CHEST 108(1):182-189 DANDURAND RJ; MATTHEWS PM; ARNOLD DL; EIDELMAN DH MITOCHONDRIAL DISEASE - PULMONARY-FUNCTION, EXERCISE PERFORMANCE, AND BLOOD LACTATE LEVELS	16	7
3667	10	9599 1995 DNA AND CELL BIOLOGY 14(1):61-71 BEETHAM JK; GRANT D; ARAND M; GARBARINO J; KIYOSUE T; PINOT F; OESCH F; BELKNAP WR; SHINOZAKI K; HAMMOCK BD GENE EVOLUTION OF EPOXIDE HYDROLASES AND RECOMMENDED NOMENCLATURE	68	7
3668	36	9617 1995 DRUG METABOLISM AND DISPOSITION 23(7):736-748 BULLOCK P; PEARCE R; DRAPER A; PODVAL J; BRACKEN W; VELTMAN J; THOMAS P; PARKINSON A INDUCTION OF LIVER MICROSOMAL CYTOCHROME-P450 IN CYNOMOLGUS MONKEYS	17	7
3669	13	9644 1995 ENDOCRINE REVIEWS 16(3):322-353 EHRMANN DA; BARNES RB; ROSENFIELD RL POLYCYSTIC-OVARY-SYNDROME AS A FORM OF FUNCTIONAL OVARIAN HYPERANDROGENISM DUE TO DYSREGULATION OF ANDROGEN SECRETION	180	7
3670	11	9667 1995 FEBS LETTERS 364(1):79-82 MURRAY GI; PRITCHARD S; MELVIN WT; BURKE MD CYTOCHROME-P450 CYP3A5 IN THE HUMAN ANTERIOR-PITUITARY GLAND	10	7
3671	11	9721 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(21):12569-12577 TOLLET P; HAMBERG M; GUSTAFSSON JA; MODE A GROWTH-HORMONE SIGNALING LEADING TO CYP2C12 GENE-EXPRESSION IN RAT HEPATOCYTES INVOLVES PHOSPHOLIPASE A(2)	28	7
3672	25	9728 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(42):24707-24718 GRUENKE LD; KONOPKA K; CADIEU M; WASKELL L THE STOICHIOMETRY OF THE CYTOCHROME P-450-CATALYZED METABOLISM OF METHOXYFLURANE AND BENZPHETAMINE IN THE PRESENCE AND ABSENCE OF CYTOCHROME B(5)	18	7
3673	14	9729 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(43):25402-25410 VENEPALLY P; WATERMAN MR 2 SP1-BINDING SITES MEDIATE CAMP-INDUCED TRANSCRIPTION OF THE BOVINE CYP11A GENE THROUGH THE PROTEIN-KINASE-A SIGNALING PATHWAY	65	7
3674	9	9736 1995 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 80(2):424-429 GELEY S; JOHRER K; PETER M; DENNER K; BERNHARDT R; SIPPELL WG; KOFLER R AMINO-ACID SUBSTITUTION R384P IN ALDOSTERONE SYNTHASE CAUSES CORTICOSTERONE METHYLOXIDASE TYPE-I DEFICIENCY	25	7
3675	7	9769 1995 JOURNAL OF PATHOLOGY 177(2):147-152 MURRAY GI; TAYLOR VE; MCKAY JA; WEAVER RJ; EWEN SWB; MELVIN WT; BURKE D THE IMMUNOHISTOCHEMICAL LOCALIZATION OF DRUG-METABOLIZING- ENZYMES IN PROSTATE-CANCER	34	7
3676	11	9809 1995 MOLECULAR AND CELLULAR BIOLOGY 15(9):4672-4682 SUBRAMANIAN A; TEIXEIRA J; WANG JM; GIL G A STAT FACTOR MEDIATES THE SEXUALLY DIMORPHIC REGULATION OF HEPATIC CYTOCHROME-P450 3A10/LITHOCHOLIC ACID 6-BETA- HYDROXYLASE GENE-EXPRESSION BY GROWTH-HORMONE	46	7
3677	11	9986 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 336(1):97-104 Koza RA; Kozak UC; Brown LJ; Leiter EH; MacDonald MJ; Kozak LP Sequence and tissue-dependent RNA expression of mouse FAD- Linked glycerol-3-phosphate dehydrogenase	13	7
3678	7	10011 1996 BIOCHEMICAL JOURNAL 313():1029-1037 Geneste O; Raffalli F; Lang MA Identification and characterization of a 44 kDa protein that binds specifically to the 3'-untranslated region of CYP2a5 mRNA: Inducibility, subcellular distribution and possible role in mRNA stabilization	19	7
3679	10	10020 1996 BIOCHEMICAL PHARMACOLOGY 51(8):1003-1008 Miners JO; Coulter S; Tukey RH; Veronese ME; Birkett DJ Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen	21	7
3680	10	10093 1996 CARCINOGENESIS 17(7):1477-1481 Nakajima T; Wang RS; Nimura Y; Pin YM; He M; Vainio H; Murayama N; Aoyama T; Iida F Expression of cytochrome P450s and glutathione S-transferases in human esophagus with squamous-cell carcinomas	27	7
3681	13	10101 1996 CHEMICAL RESEARCH IN TOXICOLOGY 9(1):318-325 Barr DP; Martin MV; Guengerich FP; Mason RP Reaction of cytochrome P450 with cumene hydroperoxide: ESR spin trapping evidence for the homolytic scission of the peroxide O- O bond by ferric cytochrome P450 1A2	24	7
3682	10	10113 1996 CLINICAL PHARMACOKINETICS 30(2):141-179 Campana C; Regazzi MB; Buggia I; Molinaro M Clinically significant drug interactions with cyclosporin - An update	76	7
3683	13	10157 1996 DRUG METABOLISM AND DISPOSITION 24(9):932-939 Feierman DE; Lasker JM Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes - Role of CYP3A4	19	7
3684	7	10306 1996 JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS 24(5):461-473 Wrighton SA; VandenBranden M; Ring BJ The human drug metabolizing cytochromes P450	42	7
3685	12	10375 1996 PHARMACOGENETICS 6(1):103-111 Nagata K; Murayama N; Miyata M; Shimada M; Urahashi A; Yamazoe Y; Kato R Isolation and characterization of a new rat P450 (CYP3A18) cDNA encoding P450(6 beta-2) catalyzing testosterone 6 beta- and 16 alpha-hydroxylations	15	7
3686	15	10390 1996 PLANT PHYSIOLOGY 112(4):1411-1419 Schuler MA The role of cytochrome P450 monooxygenases in plant-insect interactions	24	7
3687	9	10394 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(14):6869-6874 Meyer K; Cusumano JC; Somerville C; Chapple CCS Ferulate-5-hydroxylase from Arabidopsis thaliana defines a new family of cytochrome P450-dependent monooxygenases	59	7
3688	19	10395 1996 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 93(22):12200-12205 Hung CF; Holzmacher R; Connolly E; Berenbaum MR; Schuler MA Conserved promoter elements in the CYP6B gene family suggest common ancestry for cytochrome P450 monooxygenases mediating furanocoumarin detoxification	26	7
3689	11	10432 1996 TRENDS IN CARDIOVASCULAR MEDICINE 6(1):4-10 McGiff JC; Steinberg M; Quilley J Missing links: Cytochrome P450 arachidonate products - A new class of lipid mediators	26	7
3690	14	10455 1996 YEAST 12(4):333-348 Kargel E; Menzel R; Honeck H; Vogel F; Bohmer A; Schunck WH Candida maltosa NADPH-cytochrome P450 reductase: Cloning of a full-length cDNA, heterologous expression in Saccharomyces cerevisiae and function of the N-terminal region for membrane anchoring and proliferation of the endoplasmic reticulum	22	7
3691	12	10477 1997 AQUATIC TOXICOLOGY 38(4):205-224 Livingstone DR; Nasci C; Sole M; DaRos L; OHara SCM; Peters LD; Fossato V; Wootton AN; Goldfarb PS Apparent induction of a cytochrome P450 with immunochemical similarities to CYP1A in digestive gland of the common mussel (Mytilus galloprovincialis L) with exposure to 2,2',3,4,4',5'- hexachlorobiphenyl and Arochlor 1254	30	7
3692	15	10480 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 337(1):1-7 Lu P; Alterman MA; Chaurasia CS; Bambal RB; Hanzlik RP Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation	11	7
3693	18	10486 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 338(2):157-164 Richardson TH; Griffin KJ; Jung F; Raucy JL; Johnson EF Targeted antipeptide antibodies to cytochrome P450 2C18 based on epitope mapping of an inhibitory monoclonal antibody to P450 2C5	22	7
3694	23	10517 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 347(2):181-192 Savas U; Carstens CP; Jefcoate CR Biological oxidations and P450 reactions - Recombinant mouse CYP1B1 expressed in Escherichia coli exhibits selective binding by polycyclic hydrocarbons and metabolism which parallels C3H10T1/2 cell microsomes, but differs from human recombinant CYP1B1	28	7
3695	20	10543 1997 BIOCHEMICAL JOURNAL 323():65-70 Longo V; Amato G; Santucci A; Gervasi PG Purification and characterization of three constitutive cytochrome P-450 isoforms from bovine olfactory epithelium	10	7
3696	16	10556 1997 BIOCHEMICAL PHARMACOLOGY 54(7):841-846 Wright MC; Edwards RJ; Pimenta M; Ribeiro V; Ratra GS; Lechner MC; Paine AJ Developmental changes in the constitutive and inducible expression of cytochrome P450 3A2	14	7
3697	12	10601 1997 CANCER RESEARCH 57(21):4830-4837 Chen L; Li LJ; Waxman DJ Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene	27	7
3698	23	10615 1997 CHEMICAL RESEARCH IN TOXICOLOGY 10(5):600-608 Kent UM; Bend JR; Chamberlin BA; Gage DA; Hollenberg PF Mechanism-based inactivation of cytochrome P450 2B1 by N- benzyl-1-aminobenzotriazole	12	7
3699	29	10625 1997 CLINICAL CHEMISTRY 43(2):254-266 Linder MW; Prough RA; Valdes R Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency	63	7
3700	28	10683 1997 ENVIRONMENTAL HEALTH PERSPECTIVES 105():767-774 Pelkonen O; Raunio H Metabolic activation of toxins: Tissue-specific expression and metabolism in target organs	28	7

#	Cited nodes	Nodes / Authors	GCS	LCS
3701	10	10732 1997 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(5):377-385 Hung CF; Berenbaum MR; Schuler MA Isolation and characterization of CYP6B4, a furanocoumarin- inducible cytochrome P450 from a Polyphagous caterpillar (Lepidoptera: Papilionidae)	18	7
3702	16	10792 1997 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 282(2):1122-1129 Sidhu JS; Omiecinski CJ An okadaic acid-sensitive pathway involved in the phenobarbital-mediated induction of CYP2B gene expression in primary rat hepatocyte cultures	31	7
3703	13	10796 1997 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 283(3):1425-1432 Fraser DJ; Feyereisen R; Harlow GR; Halpert JR Isolation, heterologous expression and functional characterization of a novel cytochrome P450 3A enzyme from a canine liver cDNA library	15	7
3704	11	10808 1997 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 119(24):5489-5498 DeVoss JJ; Sibbesen O; Zhang ZP; deMontellano PRO Substrate docking algorithms and prediction of the substrate specificity of cytochrome P450(cam) and its L244A mutant	29	7
3705	16	10817 1997 MAYO CLINIC PROCEEDINGS 72(9):835-847 Richelson E Pharmacokinetic drug interactions of new antidepressants: A review of the effects on the metabolism of other drugs	57	7
3706	34	10820 1997 METAL SITES IN PROTEINS AND MODELS 88():175-207 Wong LL; Westlake CG; Nickerson DP Protein engineering of cytochrome P450(cam)	20	7
3707	6	10831 1997 MOLECULAR PHARMACOLOGY 51(5):703-710 Dohr O; Sinning R; Vogel C; Munzel P; Abel J Effect of transforming growth factor-beta(1) on expression of aryl hydrocarbon receptor and genes of Ah gene battery: Clues for independent down-regulation in A549 cells	20	7
3708	17	10835 1997 MOLECULAR PHARMACOLOGY 52(3):362-372 Kroetz DL; Huse LM; Thuresson A; Grillo MP Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney	24	7
3709	9	10836 1997 MOLECULAR PHARMACOLOGY 52(4):590-599 Sinal CJ; Bend JR Aryl hydrocarbon receptor-dependent induction of Cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells	56	7
3710	13	10842 1997 MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH 386(1):1-23 Josephy PD; Gruz P; Nohmi T Recent advances in the construction of bacterial genotoxicity assays	30	7
3711	8	10859 1997 PHARMACOGENETICS 7(3):247-250 Gullsten H; Agundez JAG; Benitez J; Laara E; Ladero JM; DiazRubio M; FernandezSalguero P; Gonzalez F; Rautio A; Pelkonen O; Raunio H CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis	26	7
3712	20	10862 1997 PHARMACOGENETICS 7(6):441-452 Treluyer JM; Gueret G; Cheron G; Sonnier M; Cresteil T Developmental expression of CYP2C and CYP2C-dependent activities in the human liver: in-vivo/in-vitro correlation and inducibility	26	7
3713	7	10881 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(24):12920-12925 Shinki T; Shimada H; Wakino S; Anazawa H; Hayashi M; Saruta T; DeLuca HF; Suda T Cloning and expression of rat 25-hydroxyvitamin D-3-1 alpha- hydroxylase cDNA	64	7
3714	6	10899 1997 STEROIDS 62(1):124-127 Vickery LE Molecular recognition and electron transfer in mitochondrial steroid hydroxylase systems	31	7
3715	12	10979 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 355(2):201-205 Kikuta Y; Kusunose E; Sumimoto H; Mizukami Y; Takeshige K; Sakaki T; Yabusaki Y; Kusunose M Purification and characterization of recombinant human neutrophil leukotriene B-4 omega-hydroxylase (cytochrome p450 4F3)	16	7
3716	24	10989 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 359(1):89-98 Jin RY; Koop DR; Raucy JL; Lasker JM Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4	14	7
3717	15	11027 1998 BIOCHEMICAL PHARMACOLOGY 55(6):825-830 McFadyen MCE; Melvin WT; Murray GI Regional distribution of individual forms of cytochrome P450 mRNA in normal adult human brain	23	7
3718	15	11049 1998 BIOCHEMISTRY 37(37):12852-12859 Backes WL; Batie CJ; Cawley GF Interactions among P450 enzymes when combined in reconstituted systems: Formation of a 2B4-1A2 complex with a high affinity for NADPH-cytochrome P450 reductase	14	7
3719	21	11064 1998 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1380(3):297-304 Ohmori S; Nakasa H; Asanome K; Kurose Y; Ishii I; Hosokawa M; Kitada M Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells	16	7
3720	13	11099 1998 CANCER RESEARCH 58(19):4391-4401 Jounaidi Y; Hecht JED; Waxman DJ Retroviral transfer of human cytochrome P450 genes for oxazaphosphorine-based cancer gene therapy	31	7
3721	19	11116 1998 CHEMICO-BIOLOGICAL INTERACTIONS 115(3):175-199 Lewis DFV; Eddershaw PJ; Dickens M; Tarbit MH; Goldfarb PS Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate	20	7
3722	18	11156 1998 CURRENT OPINION IN CHEMICAL BIOLOGY 2(2):263-268 Wong LL Cytochrome P450 monooxygenases	22	7
3723	22	11280 1998 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 83(3):886-895 Hellmold H; Rylander T; Magnusson M; Reihner E; Warner M; Gustafsson JA Characterization of cytochrome P450 enzymes in human breast tissue from reduction mammaplasties	22	7
3724	31	11299 1998 JOURNAL OF PHARMACEUTICAL SCIENCES 87(11):1322-1330 Wacher VJ; Silverman JA; Zhang YC; Benet LZ Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics	104	7
3725	18	11306 1998 JOURNAL OF PHYSIOLOGY-LONDON 508(3):777-792 Xiao YF; Huang L; Morgan JP Cytochrome P450: a novel system modulating Ca2+ channels and contraction in mammalian heart cells	30	7
3726	81	11440 1998 XENOBIOTICA 28(12):1129-1165 Smith G; Stubbins MJ; Harries LW; Wolf CR Molecular genetics of the human cytochrome P450 monooxygenase superfamily	25	7
3727	10	11452 1999 AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 276(3):R766-R775 Oyekan AO; McAward K; Conetta J; Rosenfeld L; McGiff JC Endothelin-1 and CYP450 arachidonate metabolites interact to promote tissue injury in DOCA-salt hypertension	0	7
3728	18	11518 1999 BIOCHEMICAL PHARMACOLOGY 58(3):525-537 Dey A; Jones JE; Nebert DW Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization	32	7
3729	13	11599 1999 DNA AND CELL BIOLOGY 18(9):723-730 Kikuta Y; Miyauchi Y; Kusunose E; Kusunose M Expression and molecular cloning of human liver leukotriene B-4 omega-hydroxylase (CYP4F2) gene	17	7
3730	7	11727 1999 JOURNAL OF CHROMATOGRAPHY B 721(1):13-19 Yamazaki H; Tanaka M; Shimada T Highly sensitive high-performance liquid chromatographic assay for coumarin 7-hydroxylation and 7-ethoxycoumarin O- deethylation by human liver cytochrome P450 enzymes	18	7
3731	13	11794 1999 MOLECULAR PHARMACOLOGY 56(3):588-597 Schlezinger JJ; White RD; Stegeman JJ Oxidative inactivation of cytochrome P-450 1A (CYP1A) stimulated by 3,3 ',4,4 '-tetrachlorobiphenyl: Production of reactive oxygen by vertebrate CYP1As	51	7
3732	12	11801 1999 MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS 442(2):113-120 Aryal P; Yoshikawa K; Terashita T; Guengerich FP; Shimada T; Oda Y Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase	11	7
3733	15	11885 1999 XENOBIOTICA 29(9):885-898 Nakajima M; Kobayashi K; Oshima K; Shimada N; Tokudome S; Chiba K; Yokoi T Activation of phenacetin O-deethylase activity by alpha- naphthoflavone in human liver microsomes	12	7
3734	19	11899 2000 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 22(3):360-366 Hukkanen J; Lassila A; Paivarinta K; Valanne S; Sarpo S; Hakkola J; Pelkonen O; Raunio H Induction and regulation of xenobiotic-metabolizing cytochrome P450s in the human A549 lung adenocarcinoma cell line	19	7
3735	10	11908 2000 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 373(1):44-55 Pikuleva IA; Tesh K; Waterman MR; Kim YC The tertiary structure of full-length bovine adrenodoxin suggests functional dimers	23	7
3736	21	11948 2000 BIOCHEMICAL PHARMACOLOGY 59(1):65-85 Nebert DW; Roe AL; Dieter MZ; Solis WA; Yang Y; Dalton TP Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis	95	7
3737	15	11952 2000 BIOCHEMICAL PHARMACOLOGY 60(3):293-306 Lewis DFV On the recognition of mammalian microsomal cytochrome P450 substrates and their characteristics - Towards the prediction of human P450 substrate specificity and metabolism	32	7
3738	9	12142 2000 JOURNAL OF INORGANIC BIOCHEMISTRY 81(3):183-190 Williams PA; Cosme J; Sridhar V; Johnson EF; McRee DE Microsomal cytochrome P4502C5: comparison to microbial P450s and unique features	23	7
3739	15	12188 2000 MOLECULAR PHARMACOLOGY 58(1):48-57 Huss JM; Kasper CB Two-stage glucocorticoid induction of CYP3A23 through both the glucocorticoid and pregnane X receptors	13	7
3740	16	12209 2000 PHARMACOGENETICS 10(5):373-388 Ozdemir V; Kalow W; Tang BK; Paterson AD; Walker SE; Endrenyi L; Kashuba ADM Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method	27	7
3741	29	12235 2000 PROTEINS-STRUCTURE FUNCTION AND GENETICS 40(4):590-612 Grinberg AV; Hannemann F; Schiffler B; Muller J; Heinemann U; Bernhardt R Adrenodoxin: Structure, stability, and electron transfer properties	33	7
3742	21	12330 2001 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 393(2):255-261 Hanna IH; Kim MS; Guengerich FP Heterologous expression of cytochrome P450 2D6 mutants, electron transfer, and catalysis of bufuralol hydroxylation: The role of aspartate 301 in structural integrity	13	7
3743	141	12927 2002 PHYSIOLOGICAL REVIEWS 82(1):131-185 Roman RJ P-450 metabolites of arachidonic acid in the control of cardiovascular function	38	7
3744	1	17 1957 JOURNAL OF BIOLOGICAL CHEMISTRY 229(2):755-762 MASSEY V; SINGER TP STUDIES ON SUCCINIC DEHYDROGENASE .6. THE REACTIVITY OF BEEF HEART SUCCINIC DEHYDROGENASE WITH ELECTRON CARRIERS	28	6
3745	1	32 1958 BIOCHIMICA ET BIOPHYSICA ACTA 28(1):108-119 NUNNIKHOVEN R AMINO ACID COMPOSITION AND SOME OTHER PROPERTIES OF YEAST CYTOCHROME-C IN COMPARISON WITH HORSE-HEART CYTOCHROME-C	27	6
3746	1	69 1959 JOURNAL OF BIOPHYSICAL AND BIOCHEMICAL CYTOLOGY 5(1):97-108 LEHNINGER AL; RAY BL; SCHNEIDER M THE SWELLING OF RAT LIVER MITOCHONDRIA BY THYROXINE AND ITS REVERSAL	170	6
3747	2	102 1960 JOURNAL OF BIOCHEMISTRY 47(5):592-599 NOZAKI M STUDIES ON CYTOCHROME-C .4. MODE OF EXISTENCE OF NATIVE AND MODIFIED CYTOCHROME-C	37	6
3748	1	121 1961 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 4(1):48-& VOSS DO; BACILA M; CAMPELLO AP RESPIRATORY CHAIN AND OXIDATIVE PHOSPHORYLATION OF RAT BRAIN MITOCHONDRIA	73	6
3749	1	153 1962 ANALYTICAL CHEMISTRY 34(12):1672-& ELLIOTT WB; TANSKI W ATTACHMENT FOR MAKING LOW TEMPERATURE SPECTRA IN A RECORDING SPECTROPHOTOMETER	17	6
3750	2	191 1962 NATURE 193(4819):979-& GIUDITTA A; STRECKER HJ MECHANISM OF INHIBITION OF 2 PURIFIED BRAIN DIAPHORASES BY AMYTAL	9	6
3751	10	212 1963 BIOCHIMICA ET BIOPHYSICA ACTA 67(2):268-& CONOVER TE; ERNSTER L DT DIAPHORASE .4. COUPLING OF EXTRAMITOCHONDRIAL REDUCED PYRIDINE NUCLEOTIDE OXIDATION TO MITOCHONDRIAL RESPIRATORY CHAIN	36	6
3752	3	215 1963 BIOCHIMICA ET BIOPHYSICA ACTA 73(4):665-& HOWLAND JL REVERSIBILITY OF INHIBITION BY 2-HEPTYL-4-HYDROXYQUINOLINE-N- OXIDE AND 2-HYDROXY-3(3-METHYLBUTYL)-1,4-NAPHTHOQUINONE OF SUCCINATE OXIDATION	31	6
3753	2	224 1963 BIOCHIMICA ET BIOPHYSICA ACTA 78(4):785-& BIGGS DR; LINNANE AW EFFECT OF OXYGEN ON COMPOSITION AND ORGANISATION OF ELECTRON TRANSPORT SYSTEM OF YEAST	31	6
3754	0	231 1963 FEDERATION PROCEEDINGS 22(2):587-& COOPER DY; ESTABROOK RW; ROSENTHAL O CYTOCHROMES IN MICROSOMES FROM CORTEX AND MEDULLA OF STEER ADRENALS	6	6
3755	0	347 1964 SCIENCE 146(364):957-& CHANCE B; ESTABROOK RW MITOCHONDRIAL STRUCTURE + FUNCTION-COMPSOTIUM	6	6
3756	2	404 1965 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY 14(2):231-& HOMMES FA OSCILLATORY REDUCTIONS OF PYRIDINE NUCLEOTIDES DURING ANAEROBIC GLYCOLYSIS IN YEASTS	10	6
3757	3	425 1965 JOURNAL OF BIOLOGICAL CHEMISTRY 240(9):3653-& LENAZ G; BEYER RE MANOMETRIC UNCERTAINTIES IN CONNECTION WITH REPORTS OF HIGH PHOSPHORUS TO OXYGEN RATIOS	27	6
3758	2	508 1966 ENDOCRINOLOGY 79(5):971-& SPATZ L; HOFMANN FG EFFECTS OF NADPH AND OTHER COFACTORS ON IN VITRO METABOLISM OF STEROIDS BY GUINEA PIG ADRENAL GLANDS	16	6
3759	0	514 1966 FEDERATION PROCEEDINGS 25(2P1):281-& CAMMER W; ESTABROOK RW ENERGY LINKED REACTIONS FOR STEROID HYDROXYLATIONS BY ADRENAL MITOCHONDRIA	6	6
3760	2	523 1966 JOURNAL OF BIOCHEMISTRY 59(1):9-& OHNISHI K STUDIES ON CYTOCHROME B .2. CRYSTALLIZATION AND SOME PROPERTIES OF CYTOCHROME B FROM LARVAE OF HOUSEFLY MUSCA DOMESTICA L	17	6
3761	4	524 1966 JOURNAL OF BIOCHEMISTRY 59(1):17-& OHNISHI K STUDIES ON CYTOCHROME B .3. COMPARISON OF CYTOCHROME BS FROM BEEF HEART MUSCLE AND LARVAE OF HOUSEFLY	13	6
3762	5	532 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(3):632-& SACKTOR B; HURLBUT EC REGULATION OF METABOLISM IN WORKING MUSCLE IN VIVO .2. CONCENTRATIONS OF ADENINE NUCLEOTIDES ARGININE PHOSPHATE AND INORGANIC PHOSPHATE IN INSECT FLIGHT MUSCLE DURING FLIGHT	69	6
3763	8	536 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(11):2644-& CARAFOLI E; GAMBLE RL; LEHNINGE.AL REBOUNDS AND OSCILLATIONS IN RESPIRATION-LINKED MOVEMENTS OF CA++ AND H+ IN RAT LIVER MITOCHONDRIA	39	6
3764	4	572 1966 ZEITSCHRIFT FUR KLINISCHE CHEMIE UND KLINISCHE BIOCHEMIE 4(4):179-& SCHOLZ R; SCHWARZ F; BUCHER T BARBITURATE UND ENERGIELIEFERNDER STOFFWECHSEL IN DER HAMOGLOBINFREI DURCHSTROMTEN LEBER DER RATTE	32	6
3765	19	583 1967 ANNUAL REVIEW OF PLANT PHYSIOLOGY 18():147-& GREEN DE; SILMAN I STRUCTURE OF MITOCHONDRIAL ELECTRON TRANSFER CHAIN	31	6
3766	4	584 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 118(1):224-& MARGOLIS SA; LENAZ G; BAUM H STOICHIOMETRIC ASPECTS OF UNCOUPLING OF OXIDATIVE PHOSPHORYLATION BY CARBONYL CYANIDE PHENYLHYDRAZONES	38	6
3767	3	597 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 122(1):254-& WILSON DF NEAR INFRA-RED ELECTRONIC SPECTRA OF NON-HEME IRON PROTEINS AT - 196 DEGREES	10	6
3768	4	598 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 122(2):501-& MUSTAFA MG; KING TE WURSTERS BLUE MEDIATED OXIDATION OF NADH AND PHOSPHORYLATION IN MITOCHONDRIA	18	6
3769	5	602 1967 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 26(6):697-& BURSTEIN S CYTOCHROME P-450 CONCENTRATIONS IN ADRENAL AND LIVER MICROSOMES FROM GUINEA PIGS WITH GENETIC DIFFERENCES IN CORTISOL HYDROXYLATION	11	6
3770	3	609 1967 BIOCHEMICAL JOURNAL 103(1):1-& CHANCE B REACTIVITY OF HAEMOPROTEINS AND CYTOCHROMES	35	6
3771	2	649 1967 BIOCHIMICA ET BIOPHYSICA ACTA 143(2):340-& JONES CW; REDFEARN ER CYTOCHROME SYSTEM OF AZOTOBACTER VINELANDII	116	6
3772	1	741 1968 AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY 100(3):348-& JUCHAU MR; NISWANDE.KR; YAFFE SJ DRUG METABOLIZING SYSTEMS IN HOMOGENATES OF HUMAN IMMATURE PLACENTAS	35	6
3773	12	757 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 125(1):151-& FRENKEL R CONTROL OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE OSCILLATIONS IN BEEF HEART EXTRACTS .I. EFFECTS OF MODIFIERS OF PHOSPHOFRUCTOKINASE ACTIVITY	43	6
3774	6	759 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 125(1):166-& FRENKEL R CONTROL OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE OSCILLATIONS IN BEEF HEART EXTRACTS .3. PURIFICATION AND KINETICS OF BEEF HEART PHOSPHOFRUCTOKINASE	28	6
3775	5	766 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 126(2):585-& STOREY BT RATE OF UBIQUINONE OXIDATION IN ELECTRON TRANSPORT PARTICLES REDUCED BY SUCCINATE	13	6
3776	2	794 1968 BIOCHEMISTRY 7(2):788-& CALDWELL BV; PERON FG; MCCARTHY JL FURTHER STUDIES ON 11BETA-HYDROXYLATION OF DEOXYCORTICOSTERONE AND PROGESTERONE BY RAT ADRENAL MITOCHONDRIA	8	6
3777	5	879 1968 JOURNAL OF BIOCHEMISTRY 64(3):415-& WADA F; HIRATA K; NAKAO K; SAKAMOTO Y PARTICIPATION OF P-450 IN 7ALPHA-HYDROXYLATION OF CHOLESTEROL	36	6
3778	4	898 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(19):5153-& DAVIS WW; GARREN LD ON MECHANISM OF ACTION OF ADRENOCORTICORTICOTROPIC HORMONE - INHIBITORY SITE OF CYCLOHEXIMIDE IN PATHWAY OF STEROID BIOSYNTHESIS	98	6
3779	9	901 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(22):5827-& CASWELL AH POTENTIOMETRIC DETERMINATION OF INTERRELATIONSHIPS OF ENERGY CONSERVATION AND ION GRADIENTS IN MITOCHONDRIA	26	6
3780	5	928 1968 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 261(2):152-& UEHLEKE H; GREIM H STIMULATION OF DRUG OXIDATION IN KIDNEY MICROSOMES BY PHENOBARBITAL	17	6
3781	5	938 1968 RESPIRATION PHYSIOLOGY 4(3):292-& JOBSIS FF; STAINSBY WN OXIDATION OF NADH DURING CONTRACTIONS OF CIRCULATED MAMMALIAN SKELETAL MUSCLE	177	6
3782	1	942 1968 TOXICOLOGY AND APPLIED PHARMACOLOGY 13(3):431-& FUJII K; JAFFE H; EPSTEIN SS FACTORS INFLUENCING HEXOBARBITAL SLEEPING TIME AND ZOXAZOLAMINE PARALYSIS TIME IN MICE	28	6
3783	5	1040 1969 BIOCHIMICA ET BIOPHYSICA ACTA 187(2):250-& MARKS F; HECKER E METABOLISM AND MECHANISM OF ACTION OF OESTROGENS .12. STRUCTURE AND MECHANISM OF FORMATION OF WATER-SOLUBLE AND PROTEIN-BOUND METABOLITES OF OESTRONE IN RAT-LIVER MICROSOMES IN VITRO AND IN VIVO	114	6
3784	2	1058 1969 DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT 94(24):1265-& REMMER H; HIRSCHMA.J; GREINER I IMPORTANCE OF ACCUMULATION AND ELIMINATION IN DETERMINING DIPHENYLHYDANTOIN DOSAGE	76	6
3785	5	1093 1969 JAPANESE JOURNAL OF PHARMACOLOGY 19(1):171-& KATO R; TAKANAKA A EFFECT OF PHENOBARBITAL AND METHYLCHOLANTHRENE TREATMENT ON DRUG-INDUCED DIFFERENCE SPECTRUM OF LIVER MICROSOMES	12	6
3786	7	1149 1969 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 263(2):281-& KORANSKY W; MAGOUR S; NOACK G; HERMANN RS INFLUENCE OF INDUCING AGENTS ON DRUG-OXIDISING AND OTHER REDOX ENZYMES IN LIVER	21	6
3787	18	1202 1970 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 139(2):370-& KOVAC L; SMIGAN P; HRUSOVSK.E; HESS B INTERACTIONS OF UNCOUPLING AGENTS AND ANTIMYCIN-A WITH CYTOCHROME-B IN YEAST AND HEART MUSCLE PREPARATION UNDER ANAEROBIC CONDITIONS	19	6
3788	11	1268 1970 BIOCHIMICA ET BIOPHYSICA ACTA 218(2):320-& VANLIER JE; SMITH LL STEROL METABOLISM .15. REARRANGEMENT OF CHOLESTEROL 20ALPHA- HYDROPEROXIDE BY BOVINE ADRENAL CORTEX MITOCHONDRIAL CYTOCHROME-P-450 PREPARATIONS	21	6
3789	9	1285 1970 CANCER RESEARCH 30(9):2346-& KATO R; TAKAHASH.A DECREASED HYDROXYLATION OF STEROID HORMONES BY LIVER MICROSOMES FROM RATS BEARING WALKER CARCINOSARCOMA-256	26	6
3790	6	1293 1970 ENDOCRINOLOGY 87(2):254-& DODGE AH; CHRISTEN.AK; CLAYTON RB LOCALIZATION OF A STEROID 11 BETA-HYDROXYLASE IN INNER MEMBRANE SUBFRACTION OF RAT ADRENAL MITOCHONDRIA	53	6
3791	3	1361 1970 JOURNAL OF CELL BIOLOGY 46(1):88-& WATSON K; HASLAM JM; LINNANE AW BIOGENESIS OF MITOCHONDRIA .13. ISOLATION OF MITOCHONDRIAL STRUCTURES FROM ANAEROBICALLY GROWN - SACCHAROMYCES-CEREVISIAE	61	6
3792	12	1402 1970 PLANT PHYSIOLOGY 45(4):447-& STOREY BT RESPIRATORY CHAIN OF PLANT MITOCHONDRIA .4. OXIDATION RATES OF RESPIRATORY CARRIERS OF MUNG BEAN MITOCHONDRIA IN PRESENCE OF CYANIDE	30	6
3793	53	1431 1971 ANNUAL REVIEW OF BIOCHEMISTRY 40():115-& VANDAM K; MEYER AJ OXIDATION AND ENERGY CONSERVATION BY MITOCHONDRIA	66	6
3794	2	1469 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 43(4):935-& KRINSKY MM; FRUTON JS SPECIFICITY OF THYROID PEROXIDASE TOWARD TYROSINE PEPTIDES	21	6
3795	16	1480 1971 BIOCHEMICAL JOURNAL 124(1):123-& LIGHT PA; GARLAND PB COMPARISON OF MITOCHONDRIA FROM TORULOPSIS-UTILIS GROWN IN CONTINUOUS CULTURE WITH GLYCEROL, IRON, AMMONIUM, MAGNESIUM OR PHOSPHATE AS GROWTH-LIMITING NUTRIENT	74	6
3796	7	1501 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1371-& GRAM TE; SCHROEDE.DH; DAVIS DC; REAGAN RL; GUARINO AM ENZYMIC AND BIOCHEMICAL COMPOSITION OF SMOOTH AND ROUGH MICROSOMAL MEMBRANES FROM MONKEY, GUINEA-PIG AND MOUSE LIVER	19	6
3797	3	1503 1971 BIOCHEMICAL PHARMACOLOGY 20(7):1569-& HANSEN LG; HODGSON E BIOCHEMICAL CHARACTERISTICS OF INSECT MICROSOMES - N- DEMETHYLATION AND O-DEMETHYLATION	82	6
3798	6	1522 1971 BIOCHEMISTRY 10(16):2979-& MAHLER HR; PERLMAN PS FORMATION OF YEAST MITOCHONDRIA .6. MITOCHONDRIOGENESIS ANALYZED BY BLOCKS ON MITOCHONDRIAL TRANSLATION AND TRANSCRIPTION	45	6
3799	8	1536 1971 BIOCHIMICA ET BIOPHYSICA ACTA 245(2):321-& LUZIKOV VN; ZUBATOV AS; RAININA EI; BAKEYEVA LE DEGRADATION AND RESTORATION OF MITOCHONDRIA UPON DEAERATION AND SUBSEQUENT AERATION OF AEROBICALLY GROWN SACCHAROMYCES- CEREVISIAE CELLS	45	6
3800	2	1568 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(5):383-& MATTOCKS AR; WHITE INH CONVERSION OF PYRROLIZIDINE ALKALOIDS TO N-OXIDES AND TO DIHYDROPYRROLIZINE DERIVATIVES BY RAT-LIVER MICROSOMES IN-VITRO	172	6

#	Cited nodes	Nodes / Authors	GCS	LCS
3801	2	1581 1971 EUROPEAN JOURNAL OF BIOCHEMISTRY 23(2):366-& BOCK KW; KRAUSS E; FROHLING W REGULATION OF DELTA-AMINOLEVULINIC ACID SYNTHETASE BY DRUGS AND STEROIDS IN-VIVO AND IN ISOLATED PERFUSED RAT LIVER	45	6
3802	6	1654 1971 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 177(3):556-& DAVIS DC; SCHROEDE.DH; GRAM TE; REAGAN RL; GILLETTE JR COMPARISON OF EFFECTS OF HALOTHANE AND CCL4 ON HEPATIC DRUG METABOLIZING SYSTEM	33	6
3803	16	1726 1972 ANNUAL REVIEW OF MICROBIOLOGY 26():163-& LINNANE AW; LUKINS HB; NAGLEY P; HASLAM JM BIOGENESIS OF MITOCHONDRIA IN MICROORGANISMS	123	6
3804	4	1808 1972 BIOCHEMISTRY 11(5):855-& MUNCK E; TSIBRIS JCM; GUNSALUS IC; DEBRUNNE.PG MOSSBAUER PARAMETERS OF PUTIDAREDOXIN AND ITS SELENIUM ANALOG	100	6
3805	7	1825 1972 BIOCHIMICA ET BIOPHYSICA ACTA 267(1):37-& LUZIKOV VN; ROMASHIN.LV STUDIES ON STABILIZATION OF OXIDATIVE-PHOSPHORYLATION SYSTEM .2. ELECTRON TRANSFER-DEPENDENT RESISTANCE OF SUCCINATE OXIDASE AND NADH OXIDASE SYSTEMS OF SUBMITOCHONDRIAL PARTICLES TO PROTEINASES AND COBRA VENOM PHOSPHOLIPASE	21	6
3806	3	1831 1972 BIOCHIMICA ET BIOPHYSICA ACTA 268(2):271-& FODGE DW; HARRIS BG; GRACY RW STUDIES ON ENZYMES FROM PARASITIC HELMINTHS .1. PURIFICATION AND PHYSICAL PROPERTIES OF MALIC ENZYME FROM MUSCLE TISSUE OF ASCARIS-SUUM	72	6
3807	5	1839 1972 BIOCHIMICA ET BIOPHYSICA ACTA 283(2):223-& LEE IY; SLATER EC STUDIES ON ACCESSIBILITY BARRIER OF NADH TO CYTOCHROMES-B IN PIGEON-HEART MITOCHONDRIA	21	6
3808	4	1921 1972 JOURNAL OF BIOCHEMISTRY 72(4):807-& SAITO T; TOMITA K MALIC ENZYME-ACTIVITY IN HEART	14	6
3809	5	1935 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247(17):5569-& FRENKEL R BOVINE HEART MALIC ENZYME .2. REVERSIBILITY OF REACTION	25	6
3810	7	1957 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 182(2):320-& SOYKA LF; LONG RJ IN-VITRO INHIBITION OF DRUG-METABOLISM BY METABOLITES OF PROGESTERONE	40	6
3811	4	1992 1972 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 4(3):185-& CASTRO JA; CASTRO CRD; FERREYRA EC; FENOS OMD; DIAZGOME.MI; DACOSTA N EFFECT OF CYSTAMINE ON MIXED-FUNCTION OXYGENASE SYSTEM FROM RAT-LIVER MICROSOMES AND ITS PREVENTIVE EFFECT ON DESTRUCTION OF CYTOCHROME-P-450 BY CARBON-TETRACHLORIDE	18	6
3812	15	2045 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):208-226 MITANI F; ANDO N; HORIE S PREPARATION AND PROPERTIES OF MITOCHONDRIAL CYTOCHROME-P-450 FROM BOVINE ADRENAL-CORTEX	9	6
3813	2	2079 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 50(3):649-655 GURTOO HL BINDING OF AFLATOXIN-B1 AND ITS METABOLITES TO HEPATIC MICROSOMES	22	6
3814	11	2111 1973 BIOCHEMICAL PHARMACOLOGY 22(17):2105-2112 KORTEN K; VANDYKE RA ACUTE INTERACTION OF DRUGS .1. EFFECT OF VOLATILE ANESTHETICS ON KINETICS OF ANILINE HYDROXYLASE AND AMINOPYRINE DEMETHYLASE IN RAT HEPATIC MICROSOMES	15	6
3815	13	2167 1973 CHEMICAL & PHARMACEUTICAL BULLETIN 21(1):102-106 KAMATAKI T; SHIMOKAW.M; KITAGAWA H FURTHER STUDIES ON P-450 DIFFERENCE SPECTRA INDUCED BY VARIOUS COMPOUNDS IN LIVER-MICROSOMES FROM 3-METHYLCHOLANTHRENE TREATED RATS	8	6
3816	6	2226 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 34(2):358-368 KROGER A; KLINGENB.M; SCHWEIDL.S KINETICS OF REDOX REACTIONS OF UBIQUINONE RELATED TO ELECTRON- TRANSPORT ACTIVITY IN RESPIRATORY CHAIN	232	6
3817	7	2232 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 40(1):267-273 GIBBONS GF; MITROPOU.KA ROLE OF CYTOCHROME-P-450 IN CHOLESTEROL-BIOSYNTHESIS	48	6
3818	3	2302 1973 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 36(3):522-530 BURROW GN; SPAULDIN.SW; ALEXANDE.NM; BOWER BF NORMAL PEROXIDASE-ACTIVITY IN PENDREDS SYNDROME	30	6
3819	2	2303 1973 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 36(5):830-844 VALENTA LJ; BODE H; VICKERY AL; CAULFIEL.JB; MALOOF F LACK OF THYROID PEROXIDASE-ACTIVITY AS CAUSE OF CONGENITAL GOITROUS HYPOTHYROIDISM	26	6
3820	4	2319 1973 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 4(4):407-& DENICOLA AF; FREIRE F MITOCHONDRIAL 11 BETA HYDROXYLATION AND ADRENAL MORPHOLOGY IN RATS BEARING A MAMMOTROPIC, ACTH-SECRETING PITUITARY TUMOR	15	6
3821	5	2322 1973 LIFE SCIENCES 13(9):1151-1161 COOPER DY DISCOVERY OF FUNCTION OF HEME PROTEIN P-450 - SYSTEMATIC APPROACH TO SCIENTIFIC-RESEARCH	7	6
3822	10	2339 1973 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 277(1):39-52 ROOTS I; HILDEBRANDT AG ACTIVE CENTERS OF MICROSOMAL CYTOCHROME-P-450 DETERMINED WITH METYRAPONE BY MUTUAL DEPLETION SYSTEM KINETICS	8	6
3823	9	2340 1973 PHARMACOLOGY 9(3):129-137 FELLER DR; LUBAWY WC INTERACTIONS OF HEXOBARBITAL ENANTIOMERS WITH RAT-LIVER MICROSOMES	15	6
3824	6	2408 1974 ARCHIVES OF TOXICOLOGY 32(2):69-81 SCHMOLDT A; BENTHE HF; FRUHLING R INDUCTION OF RAT-LIVER ENZYMES BY POLYCHLORINATED BIPHENYLS (PCBS) IN DEPENDENCE ON DOSE AND CHLORINE CONTENT	31	6
3825	1	2423 1974 BIOCHEMICAL JOURNAL 143(2):365-368 BURTON K ENTHALPY CHANGE FOR REDUCTION OF NICOTINAMIDE-ADENINE DINUCLEOTIDE	22	6
3826	27	2435 1974 BIOCHEMICAL PHARMACOLOGY 23(12):1721-1731 HAYES JR; CAMPBELL TC EFFECT OF PROTEIN-DEFICIENCY ON INDUCIBILITY OF HEPATIC MICROSOMAL DRUG-METABOLIZING ENZYME-SYSTEM .3. EFFECT OF 3- METHYLCHOLANTHRENE INDUCTION ON ACTIVITY AND BINDING KINETICS	38	6
3827	16	2438 1974 BIOCHEMICAL PHARMACOLOGY 23(15):2127-2137 SCHARF R; ULLRICH V INVITRO INDUCTION BY PHENOBARBITAL OF DRUG MONOOXYGENASE ACTIVITY IN MOUSE ISOLATED SMALL-INTESTINE	20	6
3828	5	2451 1974 BIOCHEMISTRY 13(7):1543-1548 KNUTSON JC; DELUCA HF "25-HYDROXYVITAMIN-D3-24-HYDROXYLASE SUBCELLULAR LOCATION AND PROPERTIES	156	6
3829	12	2460 1974 BIOCHIMICA ET BIOPHYSICA ACTA 344(2):119-155 HARMON HJ; HALL JD; CRANE FL STRUCTURE OF MITOCHONDRIAL CRISTAE MEMBRANES	104	6
3830	8	2464 1974 BIOCHIMICA ET BIOPHYSICA ACTA 347(1):60-76 LAUNAY AN; MICHEJDA JW; VIGNAIS PV MALATE TRANSPORT IN BOVINE ADRENAL-CORTEX MITOCHONDRIA	11	6
3831	10	2491 1974 DRUG METABOLISM AND DISPOSITION 2(1):87-96 SOLIMAN MRI; JOHNSON HD; WADE AE INTERACTIONS OF INDUCERS, INHIBITORS, AND SUBSTRATES OF DRUG- METABOLIZING-ENZYMES WITH RAT-LIVER CYTOCHROME-P-450	23	6
3832	9	2698 1975 BIOCHEMICAL PHARMACOLOGY 24(12):301-303 BELINA H; COOPER SD; FARKAS R; FEUER G SEX DIFFERENCE IN PHOSPHOLIPID COMPOSITION OF RAT-LIVER MICROSOMES	32	6
3833	11	2712 1975 BIOCHEMICAL PHARMACOLOGY 24(22):2097-2099 KRAMER RE; GREINER JW; CANADY WJ; COLBY HD RELATION OF PITUITARY-GLAND TO ACTIONS OF TESTOSTERONE ON HEPATIC ETHYLMORPHINE METABOLISM IN RATS	24	6
3834	11	2722 1975 BIOCHEMICAL SOCIETY TRANSACTIONS 3(6):813-817 COON MJ; NORDBLOM GD; WHITE RE; HAUGEN DA PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 - CATALYTIC MECHANISM AND CHARACTERIZATION OF MULTIPLE FORMS	7	6
3835	5	2734 1975 BIOCHEMISTRY 14(19):4166-4171 CHIANG R; MAKINO R; SPOMER WE; HAGER LP CHLOROPEROXIDASE - P-450 TYPE ABSORPTION IN ABSENCE OF SULFHYDRYL GROUPS	45	6
3836	6	2740 1975 BIOCHIMICA ET BIOPHYSICA ACTA 379(1):262-270 NEARY JT; ARMSTRONG A; DAVIDSON B; MALOOF F; SOODAK M THYROID MICROSOMAL MEMBRANE PROTEINS - EFFECTS OF SOLUBILIZATION ON MOLECULAR-SIZE	6	6
3837	19	2768 1975 CHEMICO-BIOLOGICAL INTERACTIONS 10(1):57-70 BROWN JE; KUPFER D INTERACTIONS OF HEME WITH HEPATIC MICROSOMAL MONOOXYGENASE EFFECT ON BENZPYRENE HYDROXYLATION	28	6
3838	13	2787 1975 DRUG METABOLISM AND DISPOSITION 3(4):266-274 STERNSON LA; GAMMANS RE INTERACTION OF AROMATIC NITRO-COMPOUNDS WITH REDUCED HEPATIC MICROSOMAL CYTOCHROME-P-450	9	6
3839	10	2847 1975 JOURNAL OF BIOLOGICAL CHEMISTRY 250(6):2283-2286 HALL PF; LEWES JL; LIPSON ED ROLE OF MITOCHONDRIAL CYTOCHROME-P-450 FROM BOVINE ADRENAL- CORTEX IN SIDE-CHAIN CLEAVAGE OF 20S,22R-DIHYDROXYCHOLESTEROL	37	6
3840	11	2870 1975 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 6(3-4):401-409 HORIE S; WATANABE T PROPERTIES OF HIGH-SPIN TYPE-P-450 PREPARATIONS FROM BOVINE ADRENAL-CORTEX MITOCHONDRIA	15	6
3841	18	2875 1975 LIFE SCIENCES 16(6):985-997 PHILPOT RM; BEND JR BENZPYRENE HYDROXYLASE-ACTIVITY IN HEPATIC MICROSOMAL AND SOLUBILIZED SYSTEMS CONTAINING RABBIT OR RAT CYTOCHROME P-448 OR P-450	16	6
3842	11	2877 1975 LIFE SCIENCES 17(5):779-786 KRAMER RE; GREINER JW; COLBY HD DIVERGENCE OF GROWTH-HORMONE ACTIONS ON HEPATIC DRUG-METABOLISM IN PRESENCE AND ABSENCE OF PITUITARY-GLAND	23	6
3843	5	2881 1975 METABOLISM-CLINICAL AND EXPERIMENTAL 24(1):57-67 NIEPOMNISZCZE H; ROSENBLOOM AL; DEGROOT LJ; SHIMAOKA K; REFETOFF S; YAMAMOTO K DIFFERENTIATION OF 2 ABNORMALITIES IN THYROID PEROXIDASE CAUSING ORGANIFICATION DEFECT AND GOITROUS HYPOTHYROIDISM	28	6
3844	6	2890 1975 NATURE 256(5517):509-511 WICKRAMASINGHE RH; VILLEE CA EARLY ROLE DURING CHEMICAL EVOLUTION FOR CYTOCHROME-P450 IN OXYGEN DETOXIFICATION	23	6
3845	11	2920 1975 XENOBIOTICA 5(5):261-277 BURKE MD; BRIDGES JW; PARKE DV EFFECTS OF NONIONIC DETERGENT TWEEN 80 ON HEPATIC MICROSOMAL HYDROXYLATION	17	6
3846	6	2924 1975 XENOBIOTICA 5(11):677-686 BECKETT AH; GIBSON GG MICROSOMAL N-HYDROXYLATION OF DIBENZYLAMINE	15	6
3847	3	2954 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 172(2):600-607 KUMA F; PROUGH RA; MASTERS BSS STUDIES ON METHEMOGLOBIN REDUCTASE - IMMUNOCHEMICAL SIMILARITY OF SOLUBLE METHEMOGLOBIN REDUCTASE AND CYTOCHROME B5 OF HUMAN ERYTHROCYTES WITH NADH-CYTOCHROME B5 REDUCTASE AND CYTOCHROME B5 OF RAT-LIVER MICROSOMES	53	6
3848	7	2972 1976 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 71(3):834-839 WERRINGLOER J; ESTABROOK RW STIMULATION OF NADH OXIDATION DURING NADPH DEPENDENT MICROSOMAL ELECTRON-TRANSPORT REACTIONS	6	6
3849	17	2988 1976 BIOCHEMICAL JOURNAL 160(1):75-83 TSYRLOV IB; GROMOVA OA; LYAKHOVICH VV MECHANISM OF INHIBITION BY CARBONYL CYANIDE META- CHLOROPHENYLHYDRAZONE AND SODIUM DEOXYCHOLATE OF CYTOCHROME P- 450-CATALYZED HEPATIC MICROSOMAL DRUG-METABOLISM	9	6
3850	8	3036 1976 CANCER RESEARCH 36(10):3647-3653 PEZZUTO JM; LEA MA; YANG CS BINDING OF METABOLICALLY ACTIVATED BENZO(A)PYRENE TO NUCLEAR MACROMOLECULES	89	6
3851	13	3076 1976 ENVIRONMENTAL HEALTH PERSPECTIVES 14(APR):29-37 FRANKLIN MR METHYLENEDIOXYPHENYL INSECTICIDE SYNERGISTS AS POTENTIAL HUMAN HEALTH-HAZARDS	19	6
3852	3	3086 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 71(1):101-107 KERSCHER L; OESTERHELT D; CAMMACK R; HALL DO NEW PLANT-TYPE FERREDOXIN FROM HALOBACTERIA	63	6
3853	2	3093 1976 FEBS LETTERS 62(2):198-201 BALNY C; DEBEY P LOW-TEMPERATURE STUDIES OF MICROSOMAL CYTOCHROME-P-450 - DETERMINATION OF DISSOCIATION-CONSTANT OF [FE2+-CO] FORM	9	6
3854	8	3094 1976 FEBS LETTERS 62(3):364-368 STERN JO; PEISACH J MODEL COMPOUND FOR NITROSYL CYTOCHROME-P-450 - FURTHER EVIDENCE FOR MERCAPTIDE SULFUR LIGATION TO HEME	28	6
3855	1	3107 1976 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 357(8):1044-1045 NEBERT DW; KUMAKI K; SATO M; KON H FURTHER CHARACTERIZATION OF DRUG INTERACTIONS WITH HEPATIC MICROSOMAL CYTOCHROME-P-450	8	6
3856	4	3148 1976 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 196(2):501-509 LAUTERBURG BH; BIRCHER J EXPIRATORY MEASUREMENT OF MAXIMAL AMINOPYRINE DEMETHYLATION INVIVO - EFFECT OF PHENOBARBITAL, PARTIAL-HEPATECTOMY, PORTACAVAL-SHUNT AND BILE-DUCT LIGATION IN RAT	168	6
3857	6	3214 1976 XENOBIOTICA 6(11):679-689 HLAVICA P; KEHL M COMPARATIVE STUDIES ON N-OXIDATION OF ANILINE AND N,N- DIMETHYLANILINE BY RABBIT LIVER-MICROSOMES	15	6
3858	20	3282 1977 BIOCHEMICAL PHARMACOLOGY 26(19):1803-1807 THOMPSON JA; HOLTZMAN JL KINETICS OF ETHYLMORPHINE N-DEMETHYLASE AT LOW SUBSTRATE CONCENTRATIONS AND ITS IMPLICATIONS CONCERNING ROLE OF STIMULATION OF NADPH-CYTOCHROME P-450 REDUCTASE-ACTIVITY IN MIXED-FUNCTION OXIDASE ACTIVITY	10	6
3859	5	3288 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2117-2120 YIH TD; VANROSSUM JM KS-VALUES OF SOME HOMOLOGOUS SERIES OF BARBITURATES AND RELATIONSHIP WITH LIPOPHILICITY AND METABOLIC-CLEARANCE	35	6
3860	8	3289 1977 BIOCHEMICAL PHARMACOLOGY 26(22):2169-2173 LESCA P; LECOINTE P; PAOLETTI C; MANSUY D HYDROXYLATION OF ANTI-TUMOR AGENT, ELLIPTICINE, BY LIVER- MICROSOMES FROM DIFFERENTLY PRETREATED RATS	50	6
3861	7	3319 1977 CHEMICO-BIOLOGICAL INTERACTIONS 16(1):23-38 CUMPS J; RAZZOUK C; ROBERFROID MB MICHAELIS-MENTEN KINETIC-ANALYSIS OF HEPATIC MICROSOMAL BENZPYRENE HYDROXYLASE FROM CONTROL, PHENOBARBITAL-TREATED AND METHYL-3-CHOLANTHRENE-TREATED RATS	38	6
3862	10	3330 1977 CROATICA CHEMICA ACTA 49(2):179-206 SCHLEYER H; COOPER DY; ROSENTHAL O; CHEUNG P HEME PROTEIN-P450 FROM ADRENAL-CORTEX - ITS REACTIVITIES IN FERRIC AND FERROUS FORMS	10	6
3863	9	3359 1977 FEBS LETTERS 75(1):52-54 BEGARD E; DEBEY P; DOUZOU P SUB-ZERO TEMPERATURE STUDIES OF MICROSOMAL CYTOCHROME-P-450 - INTERACTION OF FE2+ WITH OXYGEN	7	6
3864	5	3361 1977 FEBS LETTERS 83(1):15-18 PIRRWITZ J; LASSMAN G; REIN H; RISTAU O; JANIG GR; RUCKPAUL K BINDING BEHAVIOR OF SUBSTRATE ANALOGOUS SPIN-LABELED NORMAL- ALKYLAMINES IN LIVER MICROSOMAL CYTOCHROME PARA-450	11	6
3865	14	3365 1977 GENERAL PHARMACOLOGY 8(4):243-249 IOANNIDES C; SWEATMAN B; RICHARDS R; PARKE DV DRUG-METABOLISM IN FERRET - EFFECTS OF AGE, SEX AND STRAIN	17	6
3866	20	3376 1977 JAPANESE JOURNAL OF PHARMACOLOGY 27(1):127-136 MATSUBARA T; TOUCHI A; TOCHINO Y HEPATIC AMINOPYRINE N-DEMETHYLASE SYSTEM - FURTHER-STUDIES OF ASSAY PROCEDURE	36	6
3867	10	3402 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(17):6118-6124 ISHIMARU A; YAMAZAKI I HYDROPEROXIDE-DEPENDENT HYDROXYLATION INVOLVING H2O2-REDUCIBLE HEMOPROTEIN IN MICROSOMES OF PEA SEEDS - NEW TYPE ENZYME ACTING ON HYDROPEROXIDE AND A PHYSIOLOGICAL-ROLE OF SEED LIPOXYGENASE	63	6
3868	6	3418 1977 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 203(2):409-416 KARASHIMA D; HIROKATA Y; SHIGEMATSU A; FURUKAWA T INVITRO METABOLISM OF HALOTHANE (2-BROMO-2-CHLORO-1,1,1- TRIFLUOROETHANE) BY HEPATIC MICROSOMAL CYTOCHROME-P-450	47	6
3869	20	3518 1978 BIOCHEMICAL PHARMACOLOGY 27(6):965-968 GOURLAY GK; STOCK BH PYRIDINE-NUCLEOTIDE INVOLVEMENT IN RAT HEPATIC MICROSOMAL DRUG- METABOLISM .1. FACTORS THAT INFLUENCE NADPH KINETIC ESTIMATIONS DURING MIXED-FUNCTION OXIDASE REACTIONS	21	6
3870	24	3519 1978 BIOCHEMICAL PHARMACOLOGY 27(6):969-978 GOURLAY GK; STOCK BH PYRIDINE-NUCLEOTIDE INVOLVEMENT IN RAT HEPATIC MICROSOMAL DRUG- METABOLISM .2. EVIDENCE FOR A COOPERATIVE INTERACTION BETWEEN NADPH AND NADH	8	6
3871	27	3553 1978 BIOCHIMICA ET BIOPHYSICA ACTA 544(1):185-199 HLAVICA P; AICHINGER G STUDIES ON CYTOCHROME-P-450 PRODUCT COMPLEXES FORMED DURING METABOLISM OF N,N-DIMETHYLANILINE	9	6
3872	5	3576 1978 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 60(2):193-197 FORLIN L; LIDMAN U EFFECTS OF CLOPHEN A50, 4-TETRACHLOROBIPHENYL, 2,5,2',5'-TETRA- CHLOROBIPHENYL AND 2,4,5,2',4',5'-HEXACHLOROBIPHENYL ON MIXED- FUNCTION OXIDASE SYSTEM OF RAINBOW-TROUT (SALMO-GAIRDNERII RICH) LIVER	30	6
3873	11	3611 1978 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 359(10):1247-1257 MAYER RT; SVOBODA JA; WEIRICH GF ECDYSONE 20-HYDROXYLASE IN MIDGUT MITOCHONDRIA OF MANDUCA-SEXTA (L)	38	6
3874	10	3629 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(12):4364-4369 GRAY RD KINETICS OF CO BINDING TO AND DISSOCIATION FROM MICROSOMAL CYTOCHROME-P-450 INDUCED BY PHENOBARBITAL IN RAT-LIVER	15	6
3875	33	3676 1978 PHARMAZIE 33(6):321-324 BLANCK J; SMETTAN G CYTOCHROME-P-450 REACTION-MECHANISM - KINETIC ASPECTS	7	6
3876	9	3710 1978 XENOBIOTICA 8(8):515-522 NOORDHOEK J; VANDENBERG AP; SAVENIJECHAPEL EM; KOOPMANKOOL E SEX-DIFFERENCES IN KINETIC CONSTANTS OF ETHYLMORPHINE DEMETHYLATION AND TYPE-I BINDING TO HEPATIC MICROSOMAL CYTOCHROME-P-450 IN MICE - INFLUENCE OF CASTRATION AND TESTOSTERONE	18	6
3877	6	3734 1979 ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 3(3):219-222 FABRY TL; LIEBER CS PHOTO-CHEMICAL ACTION SPECTRUM OF THE MICROSOMAL ETHANOL OXIDIZING SYSTEM	14	6
3878	5	3751 1979 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 89(2):456-463 FARRELL GC; SCHMID R; KUNZE KL; ORTIZDEMONTELLANO PR EXOGENOUS HEME RESTORES INVIVO FUNCTIONAL-CAPACITY OF HEPATIC CYTOCHROME-P-450 DESTROYED BY ALLYLISOPROPYLACETAMIDE	24	6
3879	5	3788 1979 BIOCHEMICAL PHARMACOLOGY 28(23):3425-3429 TUNEK A; OESCH F UNIQUE BEHAVIOR OF BENZENE MONO-OXYGENASE - ACTIVATION BY DETERGENT AND DIFFERENT PROPERTIES OF BENZENE-INDUCED AND PHENOBARBITAL-INDUCED MONO-OXYGENASE ACTIVITIES	27	6
3880	9	3858 1979 INSECT BIOCHEMISTRY 9(3):301-308 MCFADDEN KA; CRANKSHAW DL; HETNARSKI HK; WILKINSON CF PURIFICATION AND PROPERTIES OF CYTOCHROME-B5 FROM THE LARVAL MIDGUT OF THE SOUTHERN ARMYWORM (SPODOPTERA-ERIDANIA)	10	6
3881	3	3859 1979 INTERNATIONAL JOURNAL OF CANCER 23(3):353-357 LUBET RA; CAPDEVILA J; PROUGH RA METABOLIC ACTIVATION OF BENZO(A)PYRENE AND 9- HYDROXYBENZO(A)PYRENE BY LIVER MICROSOMAL FRACTIONS	26	6
3882	4	3878 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(7):2205-2209 MICHOT JL; NUNEZ J; JOHNSON ML; IRACE G; EDELHOCH H IODIDE BINDING AND REGULATION OF LACTOPEROXIDASE ACTIVITY TOWARD THYROID GOITEROGENS	25	6
3883	11	3907 1979 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 211(1):133-139 REINKE LA; KAUFFMAN FC; THURMAN RG STIMULATION OF PARA-NITROANISOLE O-DEMETHYLATION BY ETHANOL IN PERFUSED LIVERS FROM FASTED RATS	17	6
3884	9	3959 1979 TOXICOLOGY AND APPLIED PHARMACOLOGY 48(2):195-204 LEGRUM W; STUEHMEIER G; NETTER KJ COBALT AS A MODIFIER OF MICROSOMAL MONO-OXYGENASES IN MICE	34	6
3885	12	4023 1980 BIOCHEMICAL PHARMACOLOGY 29(3):347-351 POWIS G; WINCENTSEN L PYRIDINE-NUCLEOTIDE COFACTOR REQUIREMENTS OF INDICINE N-OXIDE REDUCTION BY HEPATIC-MICROSOMAL CYTOCHROME-P-450	24	6
3886	6	4030 1980 BIOCHEMICAL PHARMACOLOGY 29(9):1231-1238 DICKINS M; PETERSON RE EFFECTS OF A HORMONE-SUPPLEMENTED MEDIUM ON CYTOCHROME-P-450 CONTENT AND MONO-OXYGENASE ACTIVITIES OF RAT HEPATOCYTES IN PRIMARY CULTURE	59	6
3887	9	4065 1980 CANCER 45(5):1060-1065 STROBEL HW; FANG WF; OSHINSKY RJ ROLE OF COLONIC CYTOCHROME-P-450 IN LARGE BOWEL CARCINOGENESIS	35	6
3888	7	4106 1980 FEBS LETTERS 115(1):31-34 LYAKHOVICH VV; POLYAKOVA NE; POPOVA VI; EREMENKO SI; OLKIN SE; WEINER LM AFFINITY MODIFICATION OF CYTOCHROME-P450 BY IODINE-CONTAINING STABLE IMINOXYL RADICAL	8	6
3889	18	4141 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(9):4264-4277 LIGHT DR; WALSH C FLAVIN ANALOGS AS MECHANISTIC PROBES OF ADRENODOXIN REDUCTASE- DEPENDENT ELECTRON-TRANSFER TO THE CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P-450 OF THE ADRENAL-CORTEX	49	6
3890	1	4144 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(12):5508-5510 KAWATO S; SIGEL E; CARAFOLI E; CHERRY RJ CYTOCHROME-OXIDASE ROTATES IN THE INNER MEMBRANE OF INTACT MITOCHONDRIA AND SUB-MITOCHONDRIAL PARTICLES	40	6
3891	7	4145 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(14):6575-6578 NIRANJAN BG; AVADHANI NG ACTIVATION OF AFLATOXIN-B1 BY A MONO-OXYGENASE SYSTEM LOCALIZED IN RAT-LIVER MITOCHONDRIA	37	6
3892	3	4201 1980 PHARMACOLOGY & THERAPEUTICS 10(2):171-189 CASTRO CE MECHANISMS OF REACTION OF HEMEPROTEINS WITH OXYGEN AND HYDROGEN-PEROXIDE IN THE OXIDATION OF ORGANIC SUBSTRATES	17	6
3893	1	4271 1981 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 101(2):591-598 ITO A; HAYASHI SI; YOSHIDA T PARTICIPATION OF A CYTOCHROME B5-LIKE HEMOPROTEIN OF OUTER MITOCHONDRIAL-MEMBRANE (OM CYTOCHROME B) IN NADH- SEMIDEHYDROASCORBIC ACID REDUCTASE-ACTIVITY OF RAT-LIVER	46	6
3894	22	4279 1981 BIOCHEMICAL PHARMACOLOGY 30(3):181-187 BURKE MD CYTOCHROME-P-450 - A PHARMACOLOGICAL NECESSITY OR A BIOCHEMICAL CURIOSITY	31	6
3895	3	4341 1981 DRUG METABOLISM AND DISPOSITION 9(1):69-70 DAS M; SETH PK; MUKHTAR H NADH-DEPENDENT INDUCIBLE ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY IN RAT-BRAIN MITOCHONDRIA	14	6
3896	4	4344 1981 DRUG METABOLISM AND DISPOSITION 9(6):561-564 TYBRING G; VONBAHR C; BERTILSSON L; COLLSTE H; GLAUMANN H; SOLBRAND M METABOLISM OF CARBAMAZEPINE AND ITS EPOXIDE METABOLITE IN HUMAN AND RAT-LIVER INVITRO	46	6
3897	15	4392 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(10):4851-4855 GEREN LM; MILLETT F INTERACTION BETWEEN ADRENODOXIN AND CYTOCHROME-C	25	6
3898	20	4396 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(14):7213-7227 BACKES WL; CANADY WJ THE INTERACTION OF HEPATIC CYTOCHROME-P-450 WITH ORGANIC- SOLVENTS - THE EFFECT OF ORGANIC-SOLVENTS ON APPARENT SPECTRAL BINDING CONSTANTS FOR HYDROCARBON SUBSTRATES	20	6
3899	27	4442 1981 PHARMACOLOGY & THERAPEUTICS 12(1):133-158 BACKES WL; CANADY WJ METHODS FOR THE EVALUATION OF HYDROPHOBIC SUBSTRATE BINDING TO CYTOCHROME-P-450	18	6
3900	16	4477 1982 ADVANCES IN ENZYME REGULATION 20():213-& MITANI F; IIZUKA T; UENO R; ISHIMURA Y; KIMURA T; IZUMI S; KOMATSU N; WATANABE K REGULATION OF CYTOCHROME-P450 ACTIVITIES IN ADRENOCORTICAL MITOCHONDRIA FROM NORMAL RATS AND HUMAN NEOPLASTIC TISSUES	13	6

#	Cited nodes	Nodes / Authors	GCS	LCS
3901	6	4521 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 109(3):832-840 ARCHAKOV AI; BORODIN EA; DAVYDOV DR; KARYAKIN AI; BOROVYAGIN VL RANDOM DISTRIBUTION OF NADPH-SPECIFIC FLAVOPROTEIN AND CYTOCHROME-P-450 IN LIVER-MICROSOMES	19	6
3902	19	4525 1982 BIOCHEMICAL JOURNAL 204(2):425-432 HLAVICA P; MIETASCHK J; BADEN I INTERACTION OF LIGANDS WITH CYTOCHROME-P-450 - ON THE 442 NM SPECTRAL SPECIES GENERATED DURING THE OXIDATIVE-METABOLISM OF PYRIDINE	11	6
3903	5	4541 1982 BIOCHEMICAL PHARMACOLOGY 31(11):2011-2016 KENNEDY KA; SLIGAR SG; POLOMSKI L; SARTORELLI AC METABOLIC-ACTIVATION OF MITOMYCIN-C BY LIVER-MICROSOMES AND NUCLEI	82	6
3904	11	4545 1982 BIOCHEMICAL PHARMACOLOGY 31(18):3002-3005 MURRAY M; RYAN AJ INHIBITION AND ENHANCEMENT OF MIXED-FUNCTION OXIDASES BY NITROGEN-HETEROCYCLES	20	6
3905	10	4590 1982 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 71(3):431-436 SCHWEN RJ; MANNERING GJ HEPATIC CYTOCHROME P-450-DEPENDENT MONO-OXYGENASE SYSTEMS OF THE TROUT, FROG AND SNAKE .1. COMPONENTS	22	6
3906	26	4634 1982 JOURNAL OF BIOCHEMISTRY 92(6):1793-1803 SUGIYAMA T; MIKI N; MIYAKE Y; YAMANO T INTERACTION AND ELECTRON-TRANSFER BETWEEN CYTOCHROME-B5 AND CYTOCHROME-P-450 IN THE RECONSTITUTED PARA-NITROANISOLE O- DEMETHYLASE SYSTEM	14	6
3907	13	4689 1982 MOLECULAR PHARMACOLOGY 21(2):527-532 BORNHEIM LM; FRANKLIN MR METABOLIC-INTERMEDIATE COMPLEX-FORMATION REVEALS MAJOR CHANGES IN RAT HEPATIC CYTOCHROME-P-450 SUB-POPULATIONS IN ADDITION TO THOSE FORMS PREVIOUSLY PURIFIED AFTER PHENOBARBITAL, BETA- NAPHTHOFLAVONE, AND ISOSAFROLE INDUCTION	17	6
3908	1	4777 1983 BIOCHEMICAL JOURNAL 215(3):441-445 BURK RF; PATEL K; LANE JM REDUCED GLUTATHIONE PROTECTION AGAINST RAT-LIVER MICROSOMAL INJURY BY CARBON-TETRACHLORIDE - DEPENDENCE ON O-2	25	6
3909	11	4811 1983 BIOCHIMICA ET BIOPHYSICA ACTA 750(2):291-299 CHIANG JYL; MALMER M; HUTTERER F A FORM OF RABBIT LIVER CYTOCHROME-P-450 THAT CATALYZES THE 7- ALPHA-HYDROXYLATION OF CHOLESTEROL	22	6
3910	10	4977 1983 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 19(1):44-52 RIVIERE JL PROCHLORAZ, A POTENT INDUCER OF THE MICROSOMAL CYTOCHROME-P-450 SYSTEM	31	6
3911	16	5008 1983 XENOBIOTICA 13(12):707-714 MURRAY M; RYAN AJ THE INTERACTION OF ARYLALKYLBENZIMIDAZOLES AND RELATED- COMPOUNDS WITH MICROSOMAL OXIDATION	17	6
3912	26	5024 1984 ANNUAL REPORTS IN MEDICINAL CHEMISTRY 19():201-211 DEMONTELLANO PRO THE INACTIVATION OF CYTOCHROME-P-450	31	6
3913	4	5027 1984 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 19(1):29-35 MAUERSBERGER S; SCHUNCK WH; MULLER HG THE INDUCTION OF CYTOCHROME-P-450 IN THE ALKANE-UTILIZING YEAST LODDEROMYCES-ELONGISPORUS - ALTERATIONS IN THE MICROSOMAL MEMBRANE-FRACTION	25	6
3914	6	5044 1984 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 118(3):916-922 TANIGUCHI H; IMAI Y; SATO R SUBSTRATE BINDING-SITE OF MICROSOMAL CYTOCHROME-P-450 DIRECTLY FACES MEMBRANE-LIPIDS	24	6
3915	4	5053 1984 BIOCHEMICAL PHARMACOLOGY 33(4):687-689 MURRAY M; FARRELL GC DIFFERENT EFFECTS OF CARBON-TETRACHLORIDE TOXICITY AND CIRRHOSIS ON SUBSTRATE BINDING TO RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450	18	6
3916	3	5091 1984 BRITISH JOURNAL OF PHARMACOLOGY 82(4):765-767 FORSTERMANN U; NEUFANG B THE ENDOTHELIUM-DEPENDENT RELAXATION OF RABBIT AORTA - EFFECTS OF ANTIOXIDANTS AND HYDROXYLATED EICOSATETRAENOIC ACIDS	42	6
3917	8	5140 1984 FUNDAMENTAL AND APPLIED TOXICOLOGY 4(2):134-143 COON MJ; KOOP DR; REEVE LE; CRUMP BL ALCOHOL METABOLISM AND TOXICITY - ROLE OF CYTOCHROME-P-450	27	6
3918	4	5150 1984 INTERNATIONAL JOURNAL OF BIOCHEMISTRY 16(2):243-245 RAUCHOVA H; DRAHOTA Z INHIBITION OF THE GLYCEROL 3-PHOSPHATE OXIDATION BY FREE FATTY- ACIDS	12	6
3919	7	5183 1984 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 59(1):103-107 ANDERSON KE; KAPPAS A; CONNEY AH; BRADLOW HL; FISHMAN J THE INFLUENCE OF DIETARY-PROTEIN AND CARBOHYDRATE ON THE PRINCIPAL OXIDATIVE BIOTRANSFORMATIONS OF ESTRADIOL IN NORMAL SUBJECTS	77	6
3920	8	5308 1985 BIOCHEMICAL PHARMACOLOGY 34(16):2929-2935 KRIKUN G; CEDERBAUM AI EVALUATION OF MICROSOMAL PATHWAYS OF OXIDATION OF ALCOHOLS AND HYDROXYL RADICAL SCAVENGING AGENTS WITH CARBON-MONOXIDE AND COBALT PROTOPORPHYRIN-IX	11	6
3921	20	5316 1985 BIOCHEMISTRY 24(19):5115-5123 MARCUS CB; TURNER CR; JEFCOATE CR BINDING OF BENZO[A]PYRENE BY PURIFIED CYTOCHROME-P-450C	9	6
3922	3	5348 1985 CANCER RESEARCH 45(11):5617-5624 CUMMINGS SW; ANSARI GAS; GUENGERICH FP; CROUCH LS; PROUGH RA METABOLISM OF 3-TERT-BUTYL-4-HYDROXYANISOLE BY MICROSOMAL FRACTIONS AND ISOLATED RAT HEPATOCYTES	67	6
3923	5	5351 1985 CARCINOGENESIS 6(3):469-472 ODOWD JJ; BURNETT AK; WESTON A; BULLEID NJ; CRAFT JA ALTERATIONS IN THE METABOLISM OF 7,12-DIMETHYLBENZ[A]ANTHRACENE AND VARIOUS XENOBIOTICS BY RAT HEPATIC MICROSOMES FOLLOWING SUDAN-III TREATMENT INVIVO	11	6
3924	7	5393 1985 FEBS LETTERS 181(2):295-299 WOLDMAN YY; WEINER LM; GULYAEVA LF; LYAKHOVICH VV H-1-NMR STUDY OF THE INTERACTION OF AMINOPYRINE WITH PURIFIED RAT-LIVER MICROSOMAL CYTOCHROME-P-450	9	6
3925	8	5441 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(16):9265-9271 DEMONTELLANO PRO; CATALANO CE EPOXIDATION OF STYRENE BY HEMOGLOBIN AND MYOGLOBIN - TRANSFER OF OXIDIZING EQUIVALENTS TO THE PROTEIN SURFACE	142	6
3926	5	5475 1985 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 23(2):171-181 VINCENT DR; MOLDENKE AF; FARNSWORTH DE; TERRIERE LC CYTOCHROME-P-450 IN INSECTS .6. AGE DEPENDENCY AND PHENOBARBITAL INDUCTION OF CYTOCHROME-P-450, P-450-REDUCTASE, AND MONOOXYGENASE ACTIVITIES IN SUSCEPTIBLE AND RESISTANT STRAINS OF MUSCA-DOMESTICA	21	6
3927	5	5487 1985 PROSTAGLANDINS 30(5):749-767 HIRAI A; TAHARA K; TAMURA Y; SAITO H; TERANO T; YOSHIDA S INVOLVEMENT OF 5-LIPOXYGENASE METABOLITES IN ACTH-STIMULATED CORTICOSTEROIDOGENESIS IN RAT ADRENAL-GLANDS	46	6
3928	7	5622 1986 CHEMICO-BIOLOGICAL INTERACTIONS 60(3):247-263 GOKSOYR A; SOLBAKKEN JE; KLUNGSOYR J REGIOSELECTIVE METABOLISM OF PHENANTHRENE IN ATLANTIC COD (GADUS-MORHUA) - STUDIES ON THE EFFECTS OF MONOOXYGENASE INDUCERS AND ROLE OF CYTOCHROMES-P-450	15	6
3929	5	5658 1986 FUNDAMENTAL AND APPLIED TOXICOLOGY 7(1):165-169 FRANKLIN MR; FINKLE BS THE INFLUENCE OF RECOMBINANT DNA-DERIVED HUMAN AND MURINE GAMMA INTERFERONS ON MOUSE HEPATIC DRUG-METABOLISM	15	6
3930	1	5677 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(2):747-751 BUNDY GL; NIDY EG; EPPS DE; MIZSAK SA; WNUK RJ DISCOVERY OF AN ARACHIDONIC-ACID C-8 LIPOXYGENASE IN THE GORGONIAN CORAL PSEUDOPLEXAURA-POROSA	41	6
3931	7	5690 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(17):8042-8048 GARRIB A; MCMURRAY WC PURIFICATION AND CHARACTERIZATION OF GLYCEROL-3-PHOSPHATE DEHYDROGENASE (FLAVIN-LINKED) FROM RAT-LIVER MITOCHONDRIA	24	6
3932	4	5706 1986 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 108(23):7281-7286 COOK BR; REINERT TJ; SUSLICK KS SHAPE SELECTIVE ALKANE HYDROXYLATION BY METALLOPORPHYRIN CATALYSTS	186	6
3933	7	5708 1986 MARINE ENVIRONMENTAL RESEARCH 19(3):185-203 GOKSOYR A; SOLBAKKEN JE; TARLEBO J; KLUNGSOYR J INITIAL CHARACTERIZATION OF THE HEPATIC-MICROSOMAL CYTOCHROME- P-450-SYSTEM OF THE PIKED WHALE (MINKE) BALAENOPTERA- ACUTOROSTRATA	23	6
3934	12	5754 1987 AMERICAN REVIEW OF RESPIRATORY DISEASE 136(2):488-491 MCGIFF JC; CARROLL MA CYTOCHROME-P-450-RELATED ARACHIDONIC-ACID METABOLITES	22	6
3935	8	5770 1987 ARCHIVES OF TOXICOLOGY 60(1-3):43-51 SCHENKMAN JB; FAVREAU LV; MOLE J; KREUTZER DL; JANSSON I FINGERPRINTING RAT-LIVER MICROSOMAL CYTOCHROMES P-450 AS A MEANS OF DELINEATING SEXUALLY DISTINCTIVE FORMS	8	6
3936	5	5920 1987 JOURNAL OF CLINICAL INVESTIGATION 79(1):179-187 MARCUS AJ; SAFIER LB; ULLMAN HL; ISLAM N; BROEKMAN MJ; VONSCHACKY C STUDIES ON THE MECHANISM OF OMEGA-HYDROXYLATION OF PLATELET 12- HYDROXYEICOSATETRAENOIC ACID (12-HETE) BY UNSTIMULATED NEUTROPHILS	51	6
3937	7	5931 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(4-6):801-805 SIMPSON ER; MASON JI; JOHN ME; ZUBER MX; RODGERS RJ; WATERMAN MR REGULATION OF THE BIOSYNTHESIS OF STEROIDOGENIC ENZYMES	15	6
3938	1	6021 1988 ANALYTICAL BIOCHEMISTRY 173(2):456-462 HAWKINS DJ; KUHN H; PETTY EH; BRASH AR RESOLUTION OF ENANTIOMERS OF HYDROXYEICOSATETRAENOATE DERIVATIVES BY CHIRAL PHASE HIGH-PRESSURE LIQUID-CHROMATOGRAPHY	30	6
3939	3	6063 1988 BIOCHEMICAL JOURNAL 254(1):245-254 HAHN ME; GASIEWICZ TA; LINKO P; GOLDSTEIN JA THE ROLE OF THE AH LOCUS IN HEXACHLOROBENZENE-INDUCED PORPHYRIA - STUDIES IN CONGENIC C57BL/6J MICE	33	6
3940	8	6075 1988 BIOCHEMICAL PHARMACOLOGY 37(7):1371-1375 VIND C; DICH J; GRUNNET N THE CONTENT AND ACTIVITY OF CYTOCHROME-P-450 IN LONG-TERM CULTURE OF HEPATOCYTES FROM MALE AND FEMALE RATS	24	6
3941	8	6088 1988 BIOCHEMICAL PHARMACOLOGY 37(18):3505-3509 FAVREAU LV; SCHENKMAN JB CYTOCHROME-P-450 ALTERATIONS IN THE BB/WOR SPONTANEOUSLY DIABETIC RAT	10	6
3942	10	6089 1988 BIOCHEMICAL PHARMACOLOGY 37(18):3515-3521 MARIE IJ; DALET C; BLANCHARD JM; ASTRE C; SZAWLOWSKI A; SAINTAUBERT B; JOYEUX H; MAUREL P INHIBITION OF CYTOCHROME-P-450P (P450IIIA1) GENE-EXPRESSION DURING LIVER-REGENERATION FROM 2/3 HEPATECTOMY IN THE RAT	24	6
3943	8	6112 1988 BIOCHEMISTRY 27(13):4805-4814 GRAB LA; SWANSON BA; DEMONTELLANO PRO CYTOCHROME-P-450 INACTIVATION BY 3-ALKYLSYDNONES - MECHANISTIC IMPLICATIONS OF N-ALKYL AND N-ALKENYL HEME ADDUCT FORMATION	21	6
3944	5	6141 1988 CANCER AND METASTASIS REVIEWS 7(1):51-65 BRESNICK E; SIEGEL LI; HOUSER WH THE 4S BINDING-PROTEIN ACTS AS A TRANS-REGULATOR OF THE POLYCYCLIC HYDROCARBON-INDUCIBLE CYTOCHROME-P450	14	6
3945	6	6195 1988 EUROPEAN JOURNAL OF BIOCHEMISTRY 170(3):631-636 BELEZNAI Z; SZALAY L; JANCSIK V CA-2+ AND MG-2+ AS MODULATORS OF MITOCHONDRIAL L-GLYCEROL-3- PHOSPHATE DEHYDROGENASE	8	6
3946	1	6204 1988 GASTROENTEROLOGY 95(5):1326-1331 WAXMAN DJ; LAPENSON DP; KRISHNAN M; BERNARD O; KREIBICH G; ALVAREZ F ANTIBODIES TO LIVER KIDNEY MICROSOME-1 IN CHRONIC ACTIVE HEPATITIS RECOGNIZE SPECIFIC FORMS OF HEPATIC CYTOCHROME-P-450	35	6
3947	14	6220 1988 JOURNAL OF BIOCHEMICAL TOXICOLOGY 3():131-145 DUTTON DR; MCMILLEN SK; PARKINSON A PURIFICATION OF RAT-LIVER MICROSOMAL CYTOCHROME-P-450B WITHOUT THE USE OF NONIONIC DETERGENT	13	6
3948	6	6280 1988 MOLECULAR PHARMACOLOGY 33(2):231-236 ASTROFF B; ZACHAREWSKI T; SAFE S; ARLOTTO MP; PARKINSON A; THOMAS P; LEVIN W 6-METHYL-1,3,8-TRICHLORODIBENZOFURAN AS A 2,3,7,8- TETRACHLORODIBENZO-PARA-DIOXIN ANTAGONIST - INHIBITION OF THE INDUCTION OF RAT CYTOCHROME-P-450 ISOZYMES AND RELATED MONOOXYGENASE ACTIVITIES	61	6
3949	7	6316 1988 SEMINARS IN LIVER DISEASE 8(1):47-68 LIEBER CS METABOLIC EFFECTS OF ETHANOL AND ITS INTERACTION WITH OTHER DRUGS, HEPATOTOXIC AGENTS, VITAMINS, AND CARCINOGENS - A 1988 UPDATE	52	6
3950	12	6319 1988 TOXICOLOGY AND APPLIED PHARMACOLOGY 92(1):141-149 SOUHAILIELAMRI H; FARGETTON X; BENOIT E; TOTIS M; BATT AM INDUCING EFFECT OF ALBENDAZOLE ON RAT-LIVER DRUG-METABOLIZING- ENZYMES AND METABOLITE PHARMACOKINETICS	41	6
3951	9	6408 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 160(3):1227-1232 BOGGARAM V; JOHN ME; SIMPSON ER; WATERMAN MR EFFECT OF ACTH ON THE STABILITY OF MESSENGER-RNAS ENCODING BOVINE ADRENOCORTICAL P-450SCC, P-45011-BETA, P-45017-ALPHA, P- 450C21 AND ADRENODOXIN	28	6
3952	9	6429 1989 BIOCHEMICAL PHARMACOLOGY 38(4):657-664 SINCLAIR JF; WOOD SG; SMITH EL; SINCLAIR PR; KOOP DR COMPARISON OF THE FORM(S) OF CYTOCHROME-P-450 INDUCED BY ETHANOL AND GLUTETHIMIDE IN CULTURED CHICK HEPATOCYTES	20	6
3953	6	6469 1989 BIOCHEMISTRY 28(19):7947-7952 DEPILLIS GD; DEMONTELLANO PRO SUBSTRATE OXIDATION BY THE HEME EDGE OF FUNGAL PEROXIDASES - REACTION OF COPRINUS-MACRORHIZUS PEROXIDASE WITH HYDRAZINES AND SODIUM-AZIDE	38	6
3954	6	6510 1989 CANCER RESEARCH 49(19):5299-5304 JI C; MIRVISH SS; NICKOLS J; ISHIZAKI H; LEE MJ; YANG CS FORMATION OF HYDROXY DERIVATIVES, ALDEHYDES, AND NITRITE FROM N-NITROSOMETHYL-NORMAL-AMYLAMINE BY RAT-LIVER MICROSOMES AND BY PURIFIED CYTOCHROME-P-450 IIB1	22	6
3955	6	6581 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 178(3):689-692 SRIVASTAVA G; BAWDEN MJ; HANSEN AJ; MAY BK HEME MAY NOT BE A POSITIVE REGULATOR OF CYTOCHROME-P450 GENE- EXPRESSION	17	6
3956	11	6629 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(3):1602-1607 CUPP JR; VICKERY LE ADRENODOXIN WITH A COOH-TERMINAL DELETION (DES-116-128) EXHIBITS ENHANCED ACTIVITY	24	6
3957	4	6666 1989 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 37(8):1257-1263 WATANABE J; KANAI K; KANAMURA S A NEW MICROPHOTOMETRIC METHOD FOR MEASUREMENT OF CYTOCHROME-P- 450 IN SECTIONS OF LIVER	15	6
3958	13	6680 1989 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(1):33-39 KUHNVELTEN N; MEYER I; STAIB W SPECIFICITY OF STEROID BINDING TO TESTICULAR MICROSOMAL CYTOCHROME-P-450 - RELATION OF STEROID STRUCTURE TO TYPE-I SPECTRAL RESPONSES AFTER CORRECTION FOR HYDROPHOBIC ASSOCIATION WITH THE MEMBRANE	12	6
3959	10	6682 1989 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 33(2):277-286 LARROQUE C; LANGE R; MAUREL P; LANGLOIS R; VANLIER JE RAT-LIVER MICROSOMAL PROGESTERONE METABOLISM - EVIDENCE FOR DIFFERENTIAL TROLEANDOMYCIN AND PREGNENOLONE 16-ALPHA- CARBONITRILE INDUCTIVE EFFECTS IN THE CYTOCHROME-P-450-III FAMILY	10	6
3960	10	6808 1990 AMERICAN JOURNAL OF PATHOLOGY 136(6):1383-1391 PRITCHARD KA; WONG PYK; STEMERMAN MB ATHEROGENIC CONCENTRATIONS OF LOW-DENSITY-LIPOPROTEIN ENHANCE ENDOTHELIAL-CELL GENERATION OF EPOXYEICOSATRIENOIC ACID PRODUCTS	39	6
3961	5	6810 1990 AMERICAN JOURNAL OF PHYSIOLOGY 258(4):F1084-F1089 CARROLL MA; LOUZAN M; MCGIFF JC K+ ALTERS CYTOCHROME-P-450-DEPENDENT ARACHIDONATE METABOLISM BY RABBIT RENOMEDULLARY CELLS	12	6
3962	8	6833 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 280(1):217-223 DEPILLIS GD; WARIISHI H; GOLD MH; DEMONTELLANO PRO INACTIVATION OF LIGNIN PEROXIDASE BY PHENYLHYDRAZINE AND SODIUM-AZIDE	36	6
3963	10	6877 1990 BIOCHEMICAL PHARMACOLOGY 39(3):519-525 YOO JSH; PARK HS; NING SM; LEE MJ; YANG CS EFFECTS OF THIAMINE-DEFICIENCY ON HEPATIC CYTOCHROMES-P450 AND DRUG-METABOLIZING ENZYME-ACTIVITIES	13	6
3964	6	6895 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(1):7-10 PUGA A; NEBERT DW EVOLUTION OF THE P450 GENE SUPERFAMILY AND REGULATION OF THE MURINE CYP1A1 GENE	11	6
3965	2	6901 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(1):34-36 ESTABROOK RW FUTURE-DEVELOPMENTS WITH THE CYTOCHROMES-P-450 - PROMISES FOR THE APPLIED CHEMICAL AND MEDICAL SCIENCES	6	6
3966	4	6902 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(1):56-59 VANDENBOSSCHE H; MARICHAL P; GORRENS J; BELLENS D; MOEREELS H; JANSSEN PA MUTATION IN CYTOCHROME-P-450-DEPENDENT 14-ALPHA-DEMETHYLASE RESULTS IN DECREASED AFFINITY FOR AZOLE ANTIFUNGALS	70	6
3967	9	7022 1990 DRUG METABOLISM AND DISPOSITION 18(3):378-382 AOYAMA T; KORZEKWA K; MATSUNAGA T; NAGATA K; GILLETTE J; GELBOIN HV; GONZALEZ FJ CDNA-DIRECTED EXPRESSION OF RAT P450-IIA1 AND P450-IIA2 - CATALYTIC ACTIVITIES TOWARD STEROIDS AND XENOBIOTICS AND COMPARISON WITH THE ENZYMES PURIFIED FROM LIVER	11	6
3968	5	7030 1990 DRUG METABOLISM AND DISPOSITION 18(5):788-793 KENNA JG; MARTIN JL; SATOH H; POHL LR FACTORS AFFECTING THE EXPRESSION OF TRIFLUOROACETYLATED LIVER MICROSOMAL PROTEIN NEOANTIGENS IN RATS TREATED WITH HALOTHANE	60	6
3969	4	7044 1990 ENDOCRINOLOGY 126(6):2800-2808 HALES DB; SHA L; PAYNE AH GLUCOCORTICOID AND CYCLIC ADENOSINE 3'5'-MONOPHOSPHATE-MEDIATED INDUCTION OF CHOLESTEROL SIDE-CHAIN CLEAVAGE CYTOCHROME-P450 (P450SCC) IN MA-10 TUMOR LEYDIG-CELLS - INCREASES IN MESSENGER- RNA ARE CYCLOHEXIMIDE SENSITIVE	28	6
3970	3	7049 1990 ENDOCRINOLOGY 127(4):1910-1915 RAINEY WE; NAVILLE D; SAEZ JM; CARR BR; BYRD W; MAGNESS RR; MASON JI TRANSFORMING GROWTH-FACTOR-BETA INHIBITS STEROID 17-ALPHA- HYDROXYLASE CYTOCHROME-P-450 EXPRESSION IN OVINE ADRENOCORTICAL-CELLS	57	6
3971	15	7080 1990 GASTROENTEROLOGY 99(3):885-889 FARRELL GC; MURRAY M HUMAN CYTOCHROME-P450 ISOFORMS - THEIR GENETIC-HETEROGENEITY AND INDUCTION BY OMEPRAZOLE	21	6
3972	5	7141 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(20):11425-11428 KENNEDY CH; MASON RP A REEXAMINATION OF THE CYTOCHROME-P-450-CATALYZED FREE-RADICAL PRODUCTION FROM A DIHYDROPYRIDINE - EVIDENCE OF TRACE TRANSITION-METAL CATALYSIS	14	6
3973	7	7233 1990 MOLECULAR PHARMACOLOGY 37(1):130-136 RIDDICK DS; PARK SS; GELBOIN HV; MARKS GS EFFECTS OF 4-ALKYL ANALOGS OF 3,5-DIETHOXYCARBONYL-1,4-DIHYDRO- 2,4,6-TRIMETHYLPYRIDINE ON HEPATIC CYTOCHROME-P-450 HEME, APOPROTEINS, AND CATALYTIC ACTIVITIES FOLLOWING INVIVO ADMINISTRATION TO RATS	15	6
3974	14	7247 1990 MOLECULAR PHARMACOLOGY 38(5):634-643 WHEELER CW; PARK SS; GUENTHNER TM IMMUNOCHEMICAL ANALYSIS OF A CYTOCHROME-P-450IA1 HOMOLOG IN HUMAN LUNG MICROSOMES	22	6
3975	12	7259 1990 PHARMACOLOGY 40(6):301-311 FUJINO T; WEST D; PARK SS; GELBOIN HV STUDIES ON THE MECHANISM OF MONOCLONAL-ANTIBODY INHIBITION OF ENZYME-ACTIVITY OF PHENOBARBITAL-INDUCED CYTOCHROME-P-450	10	6
3976	5	7286 1990 QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS 9(3):223-226 HANSCH C; SINCLAIR JF; SINCLAIR PR INDUCTION OF CYTOCHROME-P450 BY BARBITURATES IN CHICK-EMBRYO HEPATOCYTES - A QUANTITATIVE STRUCTURE-ACTIVITY ANALYSIS	14	6
3977	17	7324 1990 XENOBIOTICA 20(9):967-978 VROMANS RM; VANDESTRAAT R; GROENEVELD M; VERMEULEN NPE ONE-ELECTRON REDUCTION OF MITOMYCIN-C BY RAT-LIVER - ROLE OF CYTOCHROME-P-450 AND NADPH-CYTOCHROME-P-450 REDUCTASE	16	6
3978	4	7346 1991 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 4(2):179-186 CHICHESTER CH; PHILPOT RM; WEIR AJ; BUCKPITT AR; PLOPPER CG CHARACTERIZATION OF THE CYTOCHROME-P-450 MONOOXYGENASE SYSTEM IN NONCILIATED BRONCHIOLAR EPITHELIAL (CLARA) CELLS ISOLATED FROM MOUSE LUNG	42	6
3979	9	7353 1991 AQUATIC TOXICOLOGY 21(1-2):81-91 JENSEN EG; SKAARE JU; EGAAS E; GOKSOYR A RESPONSE OF XENOBIOTIC METABOLIZING ENZYMES IN RAINBOW-TROUT (ONCORHYNCHUS-MYKISS) TO ENDOSULFAN, DETECTED BY ENZYME- ACTIVITIES AND IMMUNOCHEMICAL METHODS	19	6
3980	5	7356 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 284(1):158-166 DENISON MS; YAO EF CHARACTERIZATION OF THE INTERACTION OF TRANSFORMED RAT HEPATIC CYTOSOLIC AH RECEPTOR WITH A DIOXIN RESPONSIVE TRANSCRIPTIONAL ENHANCER	46	6
3981	10	7358 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 285(1):83-89 CLEJAN LA; CEDERBAUM AI ROLE OF IRON, HYDROGEN-PEROXIDE AND REACTIVE OXYGEN SPECIES IN MICROSOMAL OXIDATION OF GLYCEROL TO FORMALDEHYDE	20	6
3982	4	7378 1991 ARCHIVES OF TOXICOLOGY 65(1):39-44 WANG RS; NAKAJIMA T KINETIC-STUDIES ON TOLUENE METABOLISM IN ETHANOL-INDUCED AND PHENOBARBITAL-INDUCED RAT-LIVER MICROSOMES INVITRO	26	6
3983	5	7406 1991 BIOCHEMICAL PHARMACOLOGY 41(6-7):861-865 MASUBUCHI Y; FUJITA S; CHIBA M; KAGIMOTO N; UMEDA S; SUZUKI T IMPAIRMENT OF DEBRISOQUINE 4-HYDROXYLASE AND RELATED MONOOXYGENASE ACTIVITIES IN THE RAT FOLLOWING TREATMENT WITH PROPRANOLOL	35	6
3984	8	7414 1991 BIOCHEMICAL PHARMACOLOGY 41(12):1949-1956 MATSUURA Y; KOTANI E; IIO T; FUKUDA T; TOBINAGA S; YOSHIDA T; KUROIWA Y STRUCTURE-ACTIVITY-RELATIONSHIPS IN THE INDUCTION OF HEPATIC- MICROSOMAL CYTOCHROME-P450 BY CLOTRIMAZOLE AND ITS STRUCTURALLY RELATED-COMPOUNDS IN RATS	21	6
3985	5	7536 1991 DRUG METABOLISM AND DISPOSITION 19(4):804-808 HAMMOND DK; BJERCKE RJ; LANGONE JJ; STROBEL HW METABOLISM OF NICOTINE BY RAT-LIVER CYTOCHROMES-P-450 - ASSESSMENT UTILIZING MONOCLONAL-ANTIBODIES TO NICOTINE AND COTININE	20	6
3986	8	7541 1991 EMBO JOURNAL 10(5):1075-1081 JOWETT T; WAJIDI MFF; OXTOBY E; WOLF CR MAMMALIAN GENES EXPRESSED IN DROSOPHILA - A TRANSGENIC MODEL FOR THE STUDY OF MECHANISMS OF CHEMICAL MUTAGENESIS AND METABOLISM	25	6
3987	3	7570 1991 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 41(5):467-470 SPINA E; MARTINES C; CAPUTI AP; COBALEDA J; PINAS B; CARRILLO JA; BENITEZ J DEBRISOQUINE OXIDATION PHENOTYPE DURING NEUROLEPTIC MONOTHERAPY	51	6
3988	10	7615 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(2):735-739 ALSTON K; ROBINSON RC; PARK SS; GELBOIN HV; FRIEDMAN FK INTERACTIONS AMONG CYTOCHROMES-P-450 IN THE ENDOPLASMIC- RETICULUM - DETECTION OF CHEMICALLY CROSS-LINKED COMPLEXES WITH MONOCLONAL-ANTIBODIES	15	6
3989	4	7622 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(12):7531-7536 SHIRABE K; YUBISUI T; NISHINO T; TAKESHITA M ROLE OF CYSTEINE RESIDUES IN HUMAN NADH-CYTOCHROME-B5 REDUCTASE STUDIED BY SITE-DIRECTED MUTAGENESIS - CYS-273 AND CYS-283 ARE LOCATED CLOSE TO THE NADH-BINDING SITE BUT ARE NOT CATALYTICALLY ESSENTIAL	24	6
3990	8	7680 1991 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 259(1):470-477 KIM SG; PHILPOT RM; NOVAK RF PYRIDINE EFFECTS ON P450IIE1, IIB AND IVB EXPRESSION IN RABBIT LIVER - CHARACTERIZATION OF HIGH-AFFINITY AND LOW-AFFINITY PYRIDINE N-OXYGENASES	34	6
3991	3	7683 1991 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 259(3):1328-1334 PONS C; DANSETTE PM; AMAR C; JAOUEN M; WOLF CR; HOMBERG JGJC; MANSUY D DETECTION OF HUMAN HEPATITIS ANTI-LIVER KIDNEY MICROSOMES (LKM2) AUTOANTIBODIES ON RAT-LIVER SECTIONS IS PREDOMINANTLY DUE TO REACTIVITY WITH RAT-LIVER P-450-IIC11	16	6
3992	14	7737 1991 MUTAGENESIS 6(6):461-470 ELLARD S; MOHAMMED Y; DOGRA S; WOLFEL C; DOEHMER J; PARRY JM THE USE OF GENETICALLY ENGINEERED V79 CHINESE-HAMSTER CULTURES EXPRESSING RAT-LIVER CYP1A1, 1A2 AND 2B1 CDNAS IN MICRONUCLEUS ASSAYS	43	6
3993	2	7757 1991 PHYTOCHEMISTRY 30(9):2953-2961 BAUER W; ZENK MH 2 METHYLENEDIOXY BRIDGE FORMING CYTOCHROME-P-450 DEPENDENT ENZYMES ARE INVOLVED IN (S)-STYLOPINE BIOSYNTHESIS	28	6
3994	6	7764 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(16):7041-7045 SAITO K; NOJI M; OHMORI S; IMAI Y; MURAKOSHI I INTEGRATION AND EXPRESSION OF A RABBIT LIVER CYTOCHROME-P-450 GENE IN TRANSGENIC NICOTIANA-TABACUM	34	6
3995	3	7773 1991 PROTEIN ENGINEERING 4(6):701-708 DARWISH K; LI HY; POULOS TL ENGINEERING PROTEINS, SUBCLONING AND HYPEREXPRESSING OXIDOREDUCTASE GENES	25	6
3996	4	7796 1991 TRENDS IN NEUROSCIENCES 14(3):96-100 ORDWAY RW; SINGER JJ; WALSH JV DIRECT REGULATION OF ION CHANNELS BY FATTY-ACIDS	303	6
3997	4	7818 1992 ACS SYMPOSIUM SERIES 505():114-124 BERENBAUM MR; COHEN MB; SCHULER MA CYTOCHROME-P450 MONOOXYGENASE GENES IN OLIGOPHAGOUS LEPIDOPTERA	11	6
3998	9	7862 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(2):586-593 HALARNKAR PP; NOUROOZZADEH J; KUWANO E; JONES AD; HAMMOCK BD FORMATION OF CYCLIC PRODUCTS FROM THE DIEPOXIDE OF LONG-CHAIN FATTY ESTERS BY CYTOSOLIC EPOXIDE HYDROLASE	16	6
3999	10	7880 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(2):403-412 KANAEVA IP; NIKITYUK OV; DAVYDOV DR; DEDINSKII IR; KOEN YM; KUZNETSOVA GP; SKOTSELYAS ED; BACHMANOVA GI; ARCHAKOV AI COMPARATIVE-STUDY OF MONOMERIC RECONSTITUTED AND MEMBRANE MICROSOMAL MONOOXYGENASE SYSTEMS OF THE RABBIT LIVER .2. KINETIC-PARAMETERS OF REDUCTASE AND MONOOXYGENASE REACTIONS	11	6
4000	13	7886 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 299(2):248-254 YAMADA H; KANEKO H; TAKEUCHI K; OGURI K; YOSHIMURA H TISSUE-SPECIFIC EXPRESSION, INDUCTION, AND INHIBITION THROUGH METABOLIC INTERMEDIATE-COMPLEX FORMATION OF GUINEA-PIG CYTOCHROME-P450 BELONGING TO THE CYP2B SUBFAMILY	12	6

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