#	Cited nodes	Nodes / Authors	GCS	LCS
3101	5	1212 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 41(2):344-& OHNISHI T INDUCTION OF SITE-1 PHOSPHORYLATION IN-VIVO IN SACCHAROMYCES- CARLSBERGENSIS	29	8
3102	6	1227 1970 BIOCHEMICAL PHARMACOLOGY 19(1):27-& KAHL GF; NETTER KJ EFFECT OF METYRAPONE ON CELLULAR RESPIRATION AND MICROSOMAL DRUG OXIDATION	10	8
3103	8	1257 1970 BIOCHEMISTRY 9(24):4750-& GUTMAN M; SINGER TP SPECTROPHOTOMETRIC OBSERVATIONS ON OXIDATION-REDUCTION CYCLE OF RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE DEHYDROGENASE	18	8
3104	3	1297 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 14(1):75-& WEISS H; JAGOW GV; KLINGENB.M; BUCHER T CHARACTERIZATION OF NEUROSPORA-CRASSA MITOCHONDRIA PREPARED WITH A GRIND-MILL	157	8
3105	7	1324 1970 JAPANESE JOURNAL OF PHARMACOLOGY 20(1):157-& KATO R; ONODA K; TAKAYANA.M SPECIES AND SEX DIFFERENCES IN SUBSTRATE-INDUCED SPECTRAL CHANGE OF P-450 IN RELATION TO ACTIVITY OF DRUG OXIDATION IN LIVER MICROSOMES	12	8
3106	15	1394 1970 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 267(4):307-& KROBER F; LANGE G; MATHES S; MOR G QUALITATIVE CHANGES IN HEPATIC MICROSOMES FROM PHENOBARBITAL- TREATED RABBITS - CHANGES IN SPECTRAL DISSOCIATION CONSTANTS (KS) OF ANILINE AND N-ETHYLANILINE, IN APPARENT MICHAELIS CONSTANTS (KM) FOR HYDROXYLATION OF THESE SUBSTRATES, AND IN AFFINITY OF ENZYMES INVOLVED FOR OXYGEN AND CARBON MONOXIDE	13	8
3107	14	1444 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(1):30-& BILLIAR RB; ALOUSI MA; KNAPPENB.MH; LITTLE B DISTRIBUTION OF CHOLESTEROL SIDE-CHAIN CLEAVAGE AND 11BETA- HYDROXYLASE IN MITOCHONDRIA OF BOVINE ADRENAL CORTEX - RELEASE BY PHOSPHOLIPASE-A1	13	8
3108	5	1473 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 44(6):1572-& GUTMAN M; SINGER TP; BEINERT H EPR STUDIES ON IRON-SULFUR CENTERS OF DPNH DEHYDROGENASE DURING REDOX CYCLE OF ENZYME	28	8
3109	13	1481 1971 BIOCHEMICAL JOURNAL 124(1):171-& RAGAN CI; GARLAND PB SPECTROSCOPIC STUDIES OF FLAVOPROTEINS AND NON-HAEM IRON PROTEINS OF SUBMITOCHONDRIAL PARTICLES OF TORULOPSIS-UTILIS MODIFIED BY IRON-LIMITED AND SULPHATE-LIMITED GROWTH IN CONTINUOUS CULTURE	24	8
3110	4	1525 1971 BIOCHIMICA ET BIOPHYSICA ACTA 226(2):221-& RUZICKA FJ; CRANE FL QUINONE INTERACTION WITH RESPIRATORY CHAIN-LINKED NADH DEHYDROGENASE OF BEEF HEART MITOCHONDRIA .2. DUROQUINONE REDUCTASE ACTIVITY	66	8
3111	4	1562 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(4):279-& HOLTZMAN JL; RUMACK BH KINETICS OF ETHYLMORPHINE ACTIVATION OF NADPH-CYTOCHROME P-450 REDUCTASE ACTIVITY OF HEPATIC MICROSOMES FROM MALE AND FEMALE RATS	9	8
3112	5	1564 1971 CHEMICO-BIOLOGICAL INTERACTIONS 3(4):289-& LEIBMAN KC MODIFIERS OF MICROSOMAL DRUG OXIDATION	16	8
3113	2	1617 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(7):2320-& FUJISAWA H; HIROMI K; UYEDA M; NOZAKI M; HAYAISHI O OXYGENATED FORM OF PROTOCATECHUATE 3,4-DIOXYGENASE, A NON-HEME IRON-CONTAINING DIOXYGENASE, AS REACTION INTERMEDIATE	34	8
3114	7	1627 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(19):5960-& OHNISHI T; ASAKURA T; YONETANI T; CHANCE B ELECTRON PARAMAGNETIC RESONANCE STUDIES AT TEMPERATURES BELOW 77 DEGREES K ON IRON-SULFUR PROTEINS OF YEAST AND BOVINE HEART SUBMITOCHONDRIAL PARTICLES	46	8
3115	12	1663 1971 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 10(3):129-& ALVARES AP; SCHILLIN.G; KUNTZMAN R ALTERATION IN MICROSOMAL HEMOPROTEIN AND KINETICS OF 3,4- BENZPYRENE HYDROXYLASE INDUCED BY 3-METHYLCHOLANTHRENE - TIME COURSE STUDY AND EFFECTS OF PUROMYCIN	11	8
3116	3	1685 1971 PHARMACOLOGY 5(1):43-& GREENE FE; STRIPP B; GILLETTE JR EFFECT OF METHYLCHOLANTHRENE OR PHENOBARBITAL PRETREATMENT OF RABBITS AND RATS ON EXTINCTION COEFFICIENT FOR CYTOCHROME P-450	14	8
3117	9	1686 1971 PHARMACOLOGY 6(1):56-& STRIPP B; GREENE FE; GILLETTE JR EXTINCTION COEFFICIENTS FOR CYTOCHROME P-450 IN HEPATIC MICROSOMES FROM MALE AND FEMALE RATS	13	8
3118	4	1794 1972 BIOCHEMICAL PHARMACOLOGY 21(15):2053-& JUCHAU MR; SYMMS KG ANILINE HYDROXYLATION IN HUMAN PLACENTA - MECHANISTIC ASPECTS	52	8
3119	11	1807 1972 BIOCHEMISTRY 11(4):556-& GUTMAN M; BEINERT H; SINGER TP STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE- ADENINE DINUCLEOTIDE DEHYDROGENASE .20. RELATION OF RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE DEHYDROGENASE TO ENERGY-COUPLING SITE-1	45	8
3120	7	1820 1972 BIOCHIMICA ET BIOPHYSICA ACTA 261(1):94-& WILSON BJ; ORRENIUS S STUDY OF MODIFIED TYPE II SPECTRAL CHANGE PRODUCED BY INTERACTION OF AGROCLAVINE WITH CYTOCHROME-P-450	13	8
3121	15	1833 1972 BIOCHIMICA ET BIOPHYSICA ACTA 270(2):266-& PERON FG; TSANG CPW; HAKSAR A FURTHER STUDIES ON CORTICOSTEROIDOGENESIS .9. ENERGY-LINKED TRANSHYDROGENASE IN RAT ADRENAL-GLAND MITOCHONDRIA	12	8
3122	13	1835 1972 BIOCHIMICA ET BIOPHYSICA ACTA 273(2):318-& HLAVICA P INTERACTION OF OXYGEN AND AROMATIC-AMINES WITH HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE	13	8
3123	8	1842 1972 BIOKHIMIYA 37(3):548-& RAIKHMAN LM; ROZANTSE.EG; SHAPIRO AB; ANNAEV B MECHANISM OF FORMATION OF ENZYME - SUBSTRATE COMPLEXES IN MICROSOMAL HYDROXYLATING SYSTEM	10	8
3124	4	1878 1972 ENDOCRINOLOGY 91(6):1506-1512 MENARD RH; PURVIS JL STIMULATION OF LEVELS OF CYTOCHROME-P-450 AND 17-ALPHA- HYDROXYLASE IN CHICK TESTIS MICROSOMES BY PITUITARY HORMONES	13	8
3125	2	1959 1972 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 183(1):218-& GANG H; RUBIN E; LIEBER CS ANILINE HYDROXYLASE MICROASSAY SUITABLE FOR NEEDLE BIOPSY SPECIMENS - EFFECTS OF PHOSPHATE AND PYROPHOSPHATE ON ANILINE HYDROXYLATION	19	8
3126	8	1977 1972 MOLECULAR PHARMACOLOGY 8(3):339-& CINTI DL; SCHENKMAN JB; RITCHIE A HEPATIC ORGANELLE INTERACTION .2. EFFECT OF TRICARBOXYLIC ACID CYCLE INTERMEDIATES ON N-DEMETHYLATION AND HYDROXYLATION REACTIONS IN RAT-LIVER	23	8
3127	21	1978 1972 MOLECULAR PHARMACOLOGY 8(5):481-& HOLTZMAN JL; CARR ML INHIBITION BY DEUTERATED WATER OF MIXED-FUNCTION OXIDASES OF HEPATIC MICROSOMES OF MALE RAT	20	8
3128	11	1982 1972 MOLECULAR PHARMACOLOGY 8(6):711-& FRANKLIN MR INCOMPLETE CONVERSION OF HEPATIC CYTOCHROME-P-450 TO P-420 BY MERCURIALS	19	8
3129	19	1993 1972 PHARMACOLOGICAL REVIEWS 24(1):67-& HAWKINS RD; KALANT H METABOLISM OF ETHANOL AND ITS METABOLIC EFFECTS	284	8
3130	3	2001 1972 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 3(2):249-& WEINER M; BLAKE DA; BUTERBAU.GG INHIBITION OF HEPATIC DRUG-METABOLISM BY CYCLIC 3',5'-ADENOSINE MONOPHOSPHATE	41	8
3131	9	2041 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):94-106 KIMURA T; NAKAMURA S; HUANG JJ; CHU JW; WANG HP; TSERNOGL.D ELECTRON-TRANSPORT SYSTEM FOR ADRENOCORTICAL MITOCHONDRIAL STEROID HYDROXYLATION REACTIONS - MECHANISM OF HYDROXYLATION REACTIONS AND PROPERTIES OF FLAVOPROTEIN-IRON-SULFUR PROTEIN COMPLEX	15	8
3132	14	2051 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):392-405 MCINTOSH EN; MITANI F; UZGIRIS VI; ALONSO C; SALHANIC.HA COMPARATIVE STUDIES ON MITOCHONDRIAL AND PARTIALLY PURIFIED BOVINE CORPUS-LUTEUM CYTOCHROME-P-450	20	8
3133	5	2077 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 50(2):289-293 SHIKITA M; HALL PF; ISAKA S PURIFICATION OF CYTOCHROME P.450 FROM BOVINE ADRENOCORTICAL MITOCHONDRIA	16	8
3134	10	2107 1973 BIOCHEMICAL PHARMACOLOGY 22(13):1633-1645 BERGHEIM P; RATHGEN GH; NETTER KJ INTERACTION OF DRUGS AND STEROIDS WITH HUMAN PLACENTAL MICROSOMES	16	8
3135	5	2117 1973 BIOCHEMISTRY 12(1):76-79 TRULZSCH D; GREIM H; CZYGAN P; HUTTERER F; SCHAFFNE.F; POPPER H; COOPER DY; ROSENTHA.O CYTOCHROME-P-450 IN 7ALPHA-HYDROXYLATION OF TAURODEOXYCHOLIC ACID	31	8
3136	12	2122 1973 BIOCHEMISTRY 12(4):643-649 SAUER LA; PARK R STIMULATION BY PHOSPHATE OF MALATE TRANSPORT AND OXIDATION IN RAT ADRENAL MITOCHONDRIA	16	8
3137	6	2130 1973 BIOCHIMICA ET BIOPHYSICA ACTA 296(3):624-638 GALLO M; BERTRAND JC; ROCHE B; AZOULAY E ALKANE OXIDATION IN CANDIDA-TROPICALIS	68	8
3138	8	2176 1973 CLINICAL PHARMACOLOGY & THERAPEUTICS 14(4):727-741 CONNEY AH; LEVIN W; JACOBSON M; KUNTZMAN R EFFECTS OF DRUGS AND ENVIRONMENTAL CHEMICALS ON STEROID METABOLISM	61	8
3139	4	2183 1973 DOKLADY AKADEMII NAUK SSSR 209(4):973-976 ARCHAKOV AI; DEVICHEN.VM; KARUZINA II INTERACTION BETWEEN NADP-N-SPECIFIC AND NAD-N-SPECIFIC CHAINS OF ELECTRON-TRANSFER IN MICROSOMES	10	8
3140	15	2186 1973 DRUG METABOLISM AND DISPOSITION 1(1):6-13 SATO R; SATAKE H; IMAI Y PARTIAL-PURIFICATION AND SOME SPECTRAL PROPERTIES OF HEPATIC MICROSOMAL CYTOCHROME-P-450	25	8
3141	4	2224 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 33(3):407-417 BERRY MN; KUN E; WERNER HV REGULATORY ROLE OF REDUCING-EQUIVALENT TRANSFER FROM SUBSTRATE TO OXYGEN IN HEPATIC METABOLISM OF GLYCEROL AND SORBITOL	94	8
3142	15	2276 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(1):9-14 WILSON LD; HARDING BW OXIDATION OF 20 ALPHA-HYDROXYCHOLESTEROL BY ADRENAL-CORTEX MITOCHONDRIA	17	8
3143	12	2394 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 160(2):623-630 YANG CS ALTERATIONS OF ARYL-HYDROCARBON HYDROXYLASE SYSTEM DURING RIBOFLAVIN DEPLETION AND REPLETION	28	8
3144	13	2432 1974 BIOCHEMICAL PHARMACOLOGY 23(10):1467-1477 PATEL JM; PAWAR SS RIBOFLAVIN AND DRUG-METABOLISM IN ADULT MALE AND FEMALE RATS	38	8
3145	6	2515 1974 EUROPEAN JOURNAL OF BIOCHEMISTRY 42(2):315-324 WERNER HV; BERRY MN STIMULATORY EFFECTS OF THYROXINE ADMINISTRATION ON REDUCING - EQUIVALENT TRANSFER FROM SUBSTRATE TO OXYGEN DURING HEPATIC- METABOLISM OF SORBITOL AND GLYCEROL	45	8
3146	11	2522 1974 EUROPEAN JOURNAL OF BIOCHEMISTRY 49(1):117-127 ARTHUR JR; BOYD GS EFFECT OF INHIBITORS OF PROTEIN-SYNTHESIS ON CHOLESTEROL SIDE- CHAIN CLEAVAGE IN MITOCHONDRIA OF LUTEINIZED RAT OVARIES	43	8
3147	9	2584 1974 LIFE SCIENCES 14(10):2003-2010 BIDLACK WR; HOCHSTEI.P HYDROPEROXIDE PEROXIDASE-ACTIVITY IN LIVER-MICROSOMES	16	8
3148	12	2639 1975 ACTA BIOLOGICA ET MEDICA GERMANICA 34(8):1333-1337 MULLER D; LUBBE H; KLINGER W NADPH-DEPENDENT CYTOCHROME-P-450 REDUCTION IN LIVER-MICROSOMES OF RATS OF DIFFERENT AGES WITH AND WITHOUT PHENOBARBITAL PRETREATMENT	10	8
3149	4	2684 1975 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 63(2):496-501 CANICK JA; RYAN KJ INHIBITION OF 16A-HYDROXYTESTOSTERONE AROMATIZATION BY CARBON- MONOXIDE	18	8
3150	12	2699 1975 BIOCHEMICAL PHARMACOLOGY 24(3):369-378 LIU SJ; RAMSEY RK; FALLON HJ EFFECTS OF ETHANOL ON HEPATIC MICROSOMAL DRUG-METABOLIZING- ENZYMES IN RAT	56	8
3151	5	2703 1975 BIOCHEMICAL PHARMACOLOGY 24(8):867-870 ALGAILANY KAS; BRIDGES JW; NETTER KJ DEALKYLATION OF SOME PARA-NITROPHENYLALKYLETHERS AND THEIR ALPHA-DEUTERATED ANALOGS BY RAT-LIVER MICROSOMES	22	8
3152	16	2711 1975 BIOCHEMICAL PHARMACOLOGY 24(21):1959-1963 STONARD MD MIXED TYPE HEPATIC MICROSOMAL-ENZYME INDUCTION BY HEXACHLOROBENZENE	57	8
3153	11	2802 1975 EUROPEAN JOURNAL OF BIOCHEMISTRY 57(2):513-520 SIES H; GROSSKOPF M OXIDATION OF CYTOCHROME B5 BY HYDROPEROXIDES IN RAT-LIVER	29	8
3154	9	2861 1975 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 41(1):7-12 NELSON EB; BRYAN GT STEROID HYDROXYLATIONS BY HUMAN ADRENAL-CORTEX MICROSOMES	23	8
3155	3	2995 1976 BIOCHEMICAL PHARMACOLOGY 25(7):779-784 IVANETICH KM; BRADSHAW JJ; MARSH JA; KAMINSKY LS INTERACTION OF HEPATIC MICROSOMAL CYTOCHROME-P-450 WITH FLUROXENE (2,2,2-TRIFLUOROETHYL VINYL ETHER) INVITRO	28	8
3156	13	3008 1976 BIOCHEMISTRY 15(6):1235-1242 RAPP JP; DAHL LK MUTANT FORMS OF CYTOCHROME-P-450 CONTROLLING BOTH 18-BETA- STEROID AND 11-BETA-STEROID HYDROXYLATION IN RAT	94	8
3157	7	3064 1976 DRUG METABOLISM AND DISPOSITION 4(3):208-214 CHHABRA RS; FOUTS JR BIOCHEMICAL PROPERTIES OF SOME MICROSOMAL XENOBIOTIC- METABOLIZING ENZYMES IN RABBIT SMALL-INTESTINE	26	8
3158	15	3069 1976 DRUG METABOLISM AND DISPOSITION 4(6):556-561 BUENING MK; FRANKLIN MR FORMATION OF CYTOCHROME P-450 METABOLIC INTERMEDIATE COMPLEXES IN MICROSOMAL FRACTIONS FROM EXTRAHEPATIC TISSUES OF RABBIT	12	8
3159	7	3085 1976 EUROPEAN JOURNAL OF BIOCHEMISTRY 70(2):435-440 DEME D; POMMIER J; NUNEZ J KINETICS OF THYROGLOBULIN IODINATION AND OF HORMONE SYNTHESIS CATALYZED BY THYROID PEROXIDASE - ROLE OF IODIDE IN COUPLING REACTION	38	8
3160	2	3104 1976 GANN 67(6):899-902 OKITA K; NODA K; FUKUMOTO Y; TAKEMOTO T CYTOCHROME-P-450 IN HYPERPLASTIC LIVER NODULES DURING HEPATOCARCINOGENESIS WITH N-2-FLUORENYLACETAMIDE IN RATS	78	8
3161	11	3126 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(9):2831-2838 BERG A; GUSTAFSSON JA; INGELMANSUNDBERG M; CARLSTROM K CHARACTERIZATION OF A CYTOCHROME P-450-DEPENDENT STEROID HYDROXYLASE SYSTEM PRESENT IN BACILLUS-MEGATERIUM	44	8
3162	15	3133 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(17):5397-5407 KAHL GF; KAHL R; KUMAKI K; NEBERT DW ASSOCIATION OF AH LOCUS WITH SPECIFIC CHANGES IN METYRAPONE AND ETHYLISOCYANIDE BINDING TO MOUSE-LIVER MICROSOMES	20	8
3163	9	3155 1976 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 7(9):635-639 THOMPSON EA; SIITERI PK PARTIAL RESOLUTION OF PLACENTAL MICROSOMAL AROMATASE COMPLEX	35	8
3164	23	3248 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 183(1):317-327 EBEL RE; OKEEFFE DH; PETERSON JA STUDIES OF UNIQUE NATURE OF CYTOCHROME-P-450 ACTIVE-SITE - ELECTRON-SPIN RESONANCE SPECTROSCOPY AS A PROBE OF HEMIN IRON OF CYTOCHROME-P-450 - INFLUENCE OF BUFFER COMPOSITION, ALCOHOLS, AND NITROGENOUS LIGANDS	23	8
3165	17	3273 1977 BIOCHEMICAL PHARMACOLOGY 26(6):489-495 SUGIURA M; IWASAKI K; KATO R REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-DEPENDENT REDUCTION OF TERTIARY AMINE N-OXIDE BY LIVER MICROSOMAL CYTOCHROME-P-450	27	8
3166	12	3292 1977 BIOCHEMISTRY 16(4):593-600 UZGIRIS VI; GRAVES PE; SALHANICK HA LIGAND MODIFICATION OF CORPUS-LUTEUM MITOCHONDRIAL CYTOCHROME- P-450 SPECTRA AND CHOLESTEROL MONO-OXYGENATION - ASSAY OF ENZYME-SPECIFIC INHIBITORS	41	8
3167	6	3301 1977 BIOCHIMICA ET BIOPHYSICA ACTA 487(2):378-387 NARASIMHULU S THERMOTROPIC TRANSITIONS IN FLUIDITY OF BOVINE ADRENOCORTICAL MICROSOMAL MEMBRANE AND SUBSTRATE-CYTOCHROME P-450 BINDING REACTION	21	8
3168	4	3303 1977 BIOCHIMICA ET BIOPHYSICA ACTA 497(2):622-626 BARTOLI GM; GALEOTTI T; AZZI A PRODUCTION OF SUPEROXIDE ANIONS AND HYDROGEN-PEROXIDE IN EHRLICH ASCITES TUMOR-CELL NUCLEI	52	8
3169	3	3323 1977 CLINICA CHIMICA ACTA 77(3):301-306 KOIZUMI S; KYOYA S; MIYAWAKI T; KIDANI H; FUNABASHI T; NAKASHIMA H; NAKANUMA Y; OHTA G; ITAGAKI E; KATAGIRI M CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME-ACTIVITY AND CYTOCHROME- P-450 CONTENT IN ADRENAL MITOCHONDRIA OF A PATIENT WITH CONGENITAL LIPOID ADRENAL-HYPERPLASIA (PRADER DISEASE)	42	8
3170	7	3392 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(4):1264-1271 NEARY JT; KOEPSELL D; DAVIDSON B; ARMSTRONG A; STROUT HV; SOODAK M; MALOOF F INTERACTION OF THYROID PEROXIDASE WITH CONCANAVALIN-A COVALENTLY COUPLED TO AGAROSE	15	8
3171	12	3421 1977 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 8(3):221-228 ZACHARIAH PK; JUCHAU MR INHIBITION OF HUMAN PLACENTAL MIXED-FUNCTION OXIDATIONS WITH CARBON-MONOXIDE - REVERSAL WITH MONOCHROMATIC LIGHT	34	8
3172	2	3520 1978 BIOCHEMICAL PHARMACOLOGY 27(7):1098-1101 ANDERS MW INHIBITION AND ENHANCEMENT OF MICROSOMAL DRUG-METABOLISM BY DIETHYL MALEATE	96	8
3173	8	3543 1978 BIOCHIMICA ET BIOPHYSICA ACTA 515(3):209-237 SANDERMANN H REGULATION OF MEMBRANE ENZYMES BY LIPIDS	850	8
3174	10	3557 1978 BIOORGANICHESKAYA KHIMIYA 4(5):688-693 AKHREM AA; SHKUMATOV VM; CHASHCHIN VL STRUCTURAL ORGANIZATION OF MITOCHONDRIAL STEROID-HYDROXYLATING COMPLEXES	25	8
3175	16	3726 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):449-458 COON MJ; BLAKE RC; OPRIAN DD; BALLOU DP MECHANISTIC STUDIES WITH PURIFIED COMPONENTS OF THE LIVER MICROSOMAL HYDROXYLATION SYSTEM - SPECTRAL INTERMEDIATES IN REACTION OF CYTOCHROME-P-450 WITH PEROXY COMPOUNDS	10	8
3176	12	3730 1979 ACTA ENDOCRINOLOGICA 90(2):317-327 MITANI F; ISHIMURA Y; IZUMI S; WATANABE K IMMUNOHISTOCHEMICAL LOCALIZATION OF ADRENODOXIN AND ADRENODOXIN REDUCTASE IN BOVINE ADRENAL-CORTEX	24	8
3177	2	3771 1979 BIOCHEMICAL PHARMACOLOGY 28(6):929-935 JONES DP; SUNDBY GB; ORMSTAD K; ORRENIUS S USE OF ISOLATED KIDNEY-CELLS FOR STUDY OF DRUG-METABOLISM	140	8
3178	6	3867 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(1):15-17 CORREIA MA; FARRELL GC; SCHMID R; ORTIZDEMONTELLANO PR; YOST GS; MICO BA INCORPORATION OF EXOGENOUS HEME INTO HEPATIC CYTOCHROME-P-450 INVIVO	60	8
3179	9	3893 1979 JOURNAL OF CELL BIOLOGY 80(1):37-52 JARASCH ED; KARTENBECK J; BRUDER G; FINK A; MORRE DJ; FRANKE WW B-TYPE CYTOCHROMES IN PLASMA-MEMBRANES ISOLATED FROM RAT-LIVER, IN COMPARISON WITH THOSE OF ENDOMEMBRANES	90	8
3180	26	3944 1979 PHYSIOLOGICAL REVIEWS 59(2):353-406 FINKELSTEIN M; SHAEFER JM INBORN-ERRORS OF STEROID-BIOSYNTHESIS	72	8
3181	16	3949 1979 PROSTAGLANDINS 17(4):587-597 GREINER JW; KRAMER RE; COLBY HD INTERACTION OF PROSTAGLANDINS WITH ADRENAL MICROSOMAL CYTOCHROME-P-450 IN THE GUINEA-PIG	13	8
3182	5	3999 1980 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 204(1):207-213 BELINSKY SA; REINKE LA; KAUFFMAN FC; THURMAN RG INHIBITION OF MIXED-FUNCTION OXIDATION OF PARA-NITROANISOLE IN PERFUSED-RAT-LIVER BY 2,4-DINITROPHENOL	16	8
3183	4	4015 1980 BIOCHEMICAL JOURNAL 188(3):937-939 PAINE AJ; VILLA P; HOCKIN LJ EVIDENCE THAT LIGAND FORMATION IS A MECHANISM UNDERLYING THE MAINTENANCE OF CYTOCHROME-P-450 IN RAT-LIVER CELL-CULTURE - POTENT MAINTENANCE BY METYRAPONE	52	8
3184	4	4053 1980 BIOCHIMICA ET BIOPHYSICA ACTA 616(1):10-21 SWIERCZYNSKI J PURIFICATION AND SOME PROPERTIES OF EXTRA-MITOCHONDRIAL MALIC ENZYME FROM RAT SKELETAL-MUSCLE	29	8
3185	13	4158 1980 JOURNAL OF MOLECULAR CATALYSIS 7(2):159-167 ULLRICH V DIOXYGEN ACTIVATION BY HEME-SULFUR PROTEINS	23	8
3186	14	4187 1980 MOLECULAR PHARMACOLOGY 17(3):415-420 FRANKLIN MR; WOLF CR; SERABJITSINGH C; PHILPOT RM QUANTITATION OF 2 FORMS OF PULMONARY CYTOCHROME-P-450 IN MICROSOMES, USING SUBSTRATE SPECIFICITIES	18	8
3187	8	4188 1980 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 314(2):201-210 HEINEMEYER G; NIGAM S; HILDEBRANDT AG HEXOBARBITAL-BINDING, HYDROXYLATION AND HEXOBARBITAL-DEPENDENT HYDROGEN-PEROXIDE PRODUCTION IN HEPATIC MICROSOMES OF GUINEA- PIG, RAT AND RABBIT	22	8
3188	7	4473 1982 ACTA BIOLOGICA ET MEDICA GERMANICA 41(5):425-430 SCHWARZ D; PIRRWITZ J; COON MJ; RUCKPAUL K MOBILITY AND CLUSTERLIKE ORGANIZATION OF LIPOSOMAL CYTOCHROME- P-450 LM2 - SATURATION TRANSFER ELECTRON-PARAMAGNETIC-RES STUDIES	15	8
3189	4	4537 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1393-1400 JORDAN RA; SCHENKMAN JB RELATIONSHIP BETWEEN MALONDIALDEHYDE PRODUCTION AND ARACHIDONATE CONSUMPTION DURING NADPH-SUPPORTED MICROSOMAL LIPID-PEROXIDATION	55	8
3190	12	4628 1982 JAPANESE JOURNAL OF PHARMACOLOGY 32(1):9-21 MATSUBARA T; YOSHIHARA E; IWATA T; TOCHINO Y; HACHINO Y BIOTRANSFORMATION OF COUMARIN DERIVATIVES .1. 7-ALKOXYCOUMARIN ORTHO-DEALKYLASE IN LIVER-MICROSOMES	28	8
3191	12	4690 1982 MOLECULAR PHARMACOLOGY 22(1):221-228 UENG TH; ALVARES AP PULMONARY CYTOCHROMES P-450 FROM RABBITS TREATED WITH 3- METHYLCHOLANTHRENE	20	8
3192	5	4714 1982 TOXICOLOGY 23(2-3):197-212 TOFTGARD R; NILSEN OG EFFECTS OF XYLENE AND XYLENE ISOMERS ON CYTOCHROME-P-450 AND INVITRO ENZYMATIC-ACTIVITIES IN RAT-LIVER, KIDNEY AND LUNG	58	8
3193	12	4837 1983 CHEMICO-BIOLOGICAL INTERACTIONS 43(3):341-351 MURRAY M; RYAN AJ THE BINDING TO OXIDIZED CYTOCHROMES P-450 AND INHIBITION OF MIXED-FUNCTION OXIDASES BY ARYL-SUBSTITUTED BENZIMIDAZOLES AND RELATED-COMPOUNDS	20	8
3194	3	4838 1983 CHEMICO-BIOLOGICAL INTERACTIONS 45(1):125-135 RAHIMTULA A INVITRO METABOLISM OF 3-TERT-BUTYL-4-HYDROXYANISOLE AND ITS IRREVERSIBLE BINDING TO PROTEINS	55	8
3195	5	4855 1983 DRUG METABOLISM REVIEWS 14(5):1023-1053 ELING T; BOYD J; REED G; MASON R; SIVARAJAH K XENOBIOTIC METABOLISM BY PROSTAGLANDIN ENDOPEROXIDE SYNTHETASE	78	8
3196	5	4913 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(6):3825-3831 CONWAY JG; KAUFFMAN FC; THURMAN RG GENETIC-REGULATION OF NADPH SUPPLY IN PERFUSED MOUSE-LIVER - ROLE OF THE AH LOCUS DURING INDUCTION BY 3-METHYLCHOLANTHRENE	28	8
3197	11	4940 1983 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 18(6):715-723 KRAMER RE; MCCARTHY JL; SIMPSON ER; WATERMAN MR EFFECTS OF ACTH ON STEROIDOGENESIS IN BOVINE ADRENOCORTICAL- CELLS IN PRIMARY CULTURE - INCREASED SECRETION OF 17ALPHA- HYDROXYLATED STEROIDS ASSOCIATED WITH A REFRACTORINESS IN TOTAL STEROID OUTPUT	29	8
3198	19	5026 1984 ANNUAL REVIEW OF NUTRITION 4():207-231 GUENGERICH FP EFFECTS OF NUTRITIVE FACTORS ON METABOLIC PROCESSES INVOLVING BIOACTIVATION AND DETOXICATION OF CHEMICALS	54	8
3199	3	5208 1984 METHODS IN ENZYMOLOGY 105():283-293 SLATER TF OVERVIEW OF METHODS USED FOR DETECTING LIPID-PEROXIDATION	294	8
3200	5	5225 1984 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 81(23):7269-7273 ROSEN GM; FREEMAN BA DETECTION OF SUPEROXIDE GENERATED BY ENDOTHELIAL-CELLS	310	8

#	Cited nodes	Nodes / Authors	GCS	LCS
3201	12	5311 1985 BIOCHEMICAL PHARMACOLOGY 34(21):3881-3884 FUJII H; OHMACHI T; SAGAMI I; WATANABE M LIVER MICROSOMAL DRUG-METABOLISM IN ETHANOL-TREATED HAMSTERS	17	8
3202	14	5330 1985 BIOCHIMICA ET BIOPHYSICA ACTA 835(1):1-17 TURK J; WOLF BA; COMENS PG; COLCA J; JAKSCHIK B; MCDANIEL ML ARACHIDONIC-ACID METABOLISM IN ISOLATED PANCREATIC-ISLETS .4. NEGATIVE-ION MASS-SPECTROMETRIC QUANTITATION OF MONOOXYGENASE PRODUCT SYNTHESIS BY LIVER AND ISLETS	35	8
3203	2	5497 1985 TOXICOLOGY AND APPLIED PHARMACOLOGY 78(3):351-362 MOODY DE; LOURY DN; HAMMOCK BD EPOXIDE METABOLISM IN THE LIVER OF MICE TREATED WITH CLOFIBRATE (ETHYL-ALPHA-(PARA-CHLOROPHENOXYISOBUTYRATE)), A PEROXISOME PROLIFERATOR	35	8
3204	8	5563 1986 BIOCHEMICAL PHARMACOLOGY 35(9):1583-1588 WONG AKL; CAVALIERI E; ROGAN E DEPENDENCE OF BENZO[A]PYRENE METABOLIC PROFILE ON THE CONCENTRATION OF CUMENE HYDROPEROXIDE WITH UNINDUCED AND INDUCED RAT-LIVER MICROSOMES	24	8
3205	6	5584 1986 BIOCHEMISTRY 25(17):4797-4803 FREY AB; KREIBICH G; WADHERA A; CLARKE L; WAXMAN DJ 3-(TRIFLUOROMETHYL)-3-(M-[I-125]IODOPHENYL)DIAZIRINE PHOTOLABELS A SUBSTRATE-BINDING SITE OF RAT HEPATIC CYTOCHROME- P-450 FORM PB-4	24	8
3206	28	5638 1986 ENDOCRINE RESEARCH 12(4):315-350 JEFCOATE CR; MCNAMARA BC; DIBARTOLOMEIS MJ CONTROL OF STEROID-SYNTHESIS IN ADRENAL FASCICULATA CELLS	39	8
3207	11	5683 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(9):4122-4125 DRISCOLL WJ; OMDAHL JL KIDNEY AND ADRENAL MITOCHONDRIA CONTAIN 2 FORMS OF NADPH- ADRENODOXIN REDUCTASE-DEPENDENT IRON-SULFUR PROTEINS - ISOLATION OF THE 2 PORCINE RENAL FERREDOXINS	27	8
3208	18	5694 1986 JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY 6(3-4):161-189 WADE AE EFFECTS OF DIETARY-FAT ON DRUG-METABOLISM	27	8
3209	11	5733 1986 TETRAHEDRON LETTERS 27(50):6031-6034 ENNIS MD; BAZE ME ASYMMETRIC TOTAL SYNTHESIS OF 14(R),15(S)-EPOXYEICOSATRIENOIC, 14(S),15(R)-EPOXYEICOSATRIENOIC, 14(R),15(R)- EPOXYEICOSATRIENOIC, AND 14(S),15(S)-EPOXYEICOSATRIENOIC ACIDS	13	8
3210	13	5761 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 252(2):635-645 SCHWARTZMAN ML; PAGANO PJ; MCGIFF JC; ABRAHAM NG IMMUNOCHEMICAL STUDIES ON THE CONTRIBUTION OF NADPH CYTOCHROME- P-450 REDUCTASE TO THE CYTOCHROME-P-450-DEPENDENT METABOLISM OF ARACHIDONIC-ACID	12	8
3211	21	5763 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 256(1):179-193 KARP F; HARRIS JL; CROTEAU R METABOLISM OF MONOTERPENES - DEMONSTRATION OF THE HYDROXYLATION OF (+)-SABINENE TO (+)-CIS-SABINOL BY AN ENZYME PREPARATION FROM SAGE (SALVIA-OFFICINALIS) LEAVES	34	8
3212	8	5771 1987 ARCHIVES OF TOXICOLOGY 60(1-3):52-58 WATANABE M; FUJII H; SAGAMI I; TANNO M CHARACTERIZATION OF HEPATIC AND PULMONARY CYTOCHROMES P-450 IN 3-METHYLCHOLANTHRENE-TREATED HAMSTERS	12	8
3213	8	5787 1987 BIOCHEMICAL PHARMACOLOGY 36(5):613-619 VANDESTRAAT R; DEVRIES J; VERMEULEN NPE ROLE OF HEPATIC-MICROSOMAL AND PURIFIED CYTOCHROME-P-450 IN ONE-ELECTRON REDUCTION OF 2 QUINONE IMINES AND CONCOMITANT REDUCTION OF MOLECULAR-OXYGEN	26	8
3214	19	5811 1987 BIOCHEMISTRY 26(8):2343-2348 WAGNER SL; DEAN WL; GRAY RD ZWITTERIONIC DETERGENT MEDIATED INTERACTION OF PURIFIED CYTOCHROME-P-450LM4 FROM 5,6-BENZOFLAVONE-TREATED RABBITS WITH NADPH CYTOCHROME-P-450 REDUCTASE	12	8
3215	9	5831 1987 BIOCHIMIE 69(6-7):743-752 RIVIERE JL; CABANNE F ANIMAL AND PLANT CYTOCHROME-P-450 SYSTEMS	32	8
3216	22	5930 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 27(4-6):759-766 MILLER WL STRUCTURE OF GENES ENCODING STEROIDOGENIC ENZYMES	12	8
3217	2	5982 1987 TOXICOLOGY 45(3):319-330 BERGER ML; SOZERI T RAPID HALOGENATED HYDROCARBON TOXICITY IN ISOLATED HEPATOCYTES IS MEDIATED BY DIRECT SOLVENT EFFECTS	19	8
3218	8	6013 1988 AMERICAN JOURNAL OF PHYSIOLOGY 255(2):C214-C225 REVTYAK GE; HUGHES MJ; JOHNSON AR; CAMPBELL WB HISTAMINE STIMULATION OF PROSTAGLANDIN AND HETE SYNTHESIS IN HUMAN-ENDOTHELIAL CELLS	55	8
3219	10	6018 1988 AMERICAN REVIEW OF RESPIRATORY DISEASE 137(3):688-694 MANSOUR H; BRUNPASCAUD M; MARQUETTY C; GOUGEROTPOCIDALO MA; HAKIM J; POCIDALO JJ PROTECTION OF RAT FROM OXYGEN-TOXICITY BY INDUCERS OF CYTOCHROME-P-450 SYSTEM	25	8
3220	7	6071 1988 BIOCHEMICAL PHARMACOLOGY 37(3):415-420 MURRAY M; ZALUZNY L COMPARATIVE EFFECTS OF ANTITHROMBITIC AND ANTIMYCOTIC N- SUBSTITUTED IMIDAZOLES ON RAT HEPATIC-MICROSOMAL STEROID AND XENOBIOTIC HYDROXYLASES INVITRO	18	8
3221	9	6076 1988 BIOCHEMICAL PHARMACOLOGY 37(7):1383-1389 TERELIUS Y; INGELMANSUNDBERG M CYTOCHROME-P-450-DEPENDENT OXIDASE ACTIVITY AND HYDROXYL RADICAL PRODUCTION IN MICELLAR AND MEMBRANOUS TYPES OF RECONSTITUTED SYSTEMS	31	8
3222	7	6128 1988 BIOCHIMICA ET BIOPHYSICA ACTA 964(1):28-35 DAVIES MJ DETECTION OF PEROXYL AND ALKOXYL RADICALS PRODUCED BY REACTION OF HYDROPEROXIDES WITH HEME-PROTEINS BY ELECTRON-SPIN RESONANCE SPECTROSCOPY	105	8
3223	5	6218 1988 JOURNAL OF BACTERIOLOGY 170(4):1548-1553 SHAFIEE A; HUTCHINSON CR PURIFICATION AND RECONSTITUTION OF THE ELECTRON-TRANSPORT COMPONENTS FOR 6-DEOXYERYTHRONOLIDE B-HYDROXYLASE, A CYTOCHROME-P-450 ENZYME OF MACROLIDE ANTIBIOTIC (ERYTHROMYCIN) BIOSYNTHESIS	37	8
3224	10	6262 1988 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 29(3):307-312 MCCARTHY JL; WATERMAN MR CO-INDUCTION OF 17-ALPHA-HYDROXYLASE AND C-17,20-LYASE ACTIVITIES IN PRIMARY CULTURES OF BOVINE ADRENOCORTICAL-CELLS IN RESPONSE TO ACTH TREATMENT	20	8
3225	3	6267 1988 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 110(18):6234-6240 WALKER FA; EMRICK D; RIVERA JE; HANQUET BJ; BUTTLAIRE DH EFFECT OF HEME ORIENTATION ON THE REDUCTION POTENTIAL OF CYTOCHROME-BETA-5	67	8
3226	7	6399 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 275(2):540-550 KUKIELKA E; CEDERBAUM AI NADH-DEPENDENT MICROSOMAL INTERACTION WITH FERRIC COMPLEXES AND PRODUCTION OF REACTIVE OXYGEN INTERMEDIATES	30	8
3227	5	6421 1989 BIOCHEMICAL JOURNAL 260(3):635-640 BARNES TS; BURKE MD; MELVIN WT DIFFERENCES IN ADULT AND FETAL HUMAN CYTOCHROME-P-450 FORMS RECOGNIZED BY MONOCLONAL-ANTIBODIES WITH SPECIFICITY FOR THE P450III FAMILY	17	8
3228	1	6485 1989 BIOCHIMICA ET BIOPHYSICA ACTA 995(2):116-121 SHIMIZU T; SADEQUE AJM; HATANO M; FUJIIKURIYAMA Y BINDINGS OF AXIAL LIGANDS TO CYTOCHROME-P-450D MUTANTS - A DIFFERENCE ABSORPTION SPECTRAL STUDY	14	8
3229	26	6494 1989 BLOOD VESSELS 26(1):53-64 PROCTOR KG; CAPDEVILA JH; FALCK JR; FITZPATRICK FA; MULLANE KM; MCGIFF JC CARDIOVASCULAR AND RENAL ACTIONS OF CYTOCHROME-P-450 METABOLITES OF ARACHIDONIC-ACID	19	8
3230	4	6518 1989 CARCINOGENESIS 10(6):1119-1122 DEGAWA M; TANIMURA S; AGATSUMA T; HASHIMOTO Y HEPATOCARCINOGENIC HETEROCYCLIC AROMATIC-AMINES THAT INDUCE CYTOCHROME-P-448 ISOZYMES, MAINLY CYTOCHROME-P-448H (P-450IA2), RESPONSIBLE FOR MUTAGENIC ACTIVATION OF THE CARCINOGENS IN RAT- LIVER	56	8
3231	6	6528 1989 CHEMICAL RESEARCH IN TOXICOLOGY 2(6):400-410 SUGIYAMA K; YAO KQ; RETTIE AE; CORREIA MA INACTIVATION OF RAT HEPATIC CYTOCHROME-P-450 ISOZYMES BY 3,5- DICARBETHOXY-2,6-DIMETHYL-4-ETHYL-1,4-DIHYDROPYRIDINE	21	8
3232	10	6529 1989 CHEMICO-BIOLOGICAL INTERACTIONS 70(3-4):263-280 LEWIS DFV; IOANNIDES C; PARKE DV MOLECULAR-ORBITAL STUDIES OF OXYGEN ACTIVATION AND MECHANISMS OF CYTOCHROMES-P-450-MEDIATED OXIDATIVE-METABOLISM OF XENOBIOTICS	25	8
3233	4	6557 1989 DRUG METABOLISM AND DISPOSITION 17(3):334-340 TYNDALE RF; INABA T; KALOW W EVIDENCE IN HUMANS FOR VARIANT ALLOZYMES OF THE NONDEFICIENT SPARTEINE DEBRISOQUINE MONOOXYGENASE (P450IID1) INVITRO	34	8
3234	3	6596 1989 FEBS LETTERS 246(1-2):120-126 SALAUN JP; WEISSBART D; DURST F; PFLIEGER P; MIOSKOWSKI C EPOXIDATION OF CIS-DELTA-9 AND TRANS-DELTA-9-UNSATURATED LAURIC ACIDS BY A CYTOCHROME P-450-DEPENDENT SYSTEM FROM HIGHER-PLANT MICROSOMES	30	8
3235	9	6835 1990 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 280(2):313-319 TAMURA M; YOSHIDA S; TAMURA T; SAITOH T; TAKESHITA M EFFECT OF DIVALENT-CATIONS ON NADH-DEPENDENT AND NADPH- DEPENDENT CYTOCHROME-B5 REDUCTION BY HEPATIC MICROSOMES	16	8
3236	5	6920 1990 BIOCHEMISTRY INTERNATIONAL 20(2):381-387 SUMIMOTO H; KIKUTA Y; KUSUNOSE E; KUSUNOSE M; MINAKAMI S ANTIBODIES AGAINST RABBIT OMEGA-HYDROXYLASES OF PROSTAGLANDINS AND FATTY-ACIDS CROSS-REACT WITH LEUKOTRIENE-B4 OMEGA- HYDROXYLASE IN HUMAN NEUTROPHILS (CYTOCHROME-P-450LTB-OMEGA)	9	8
3237	48	6932 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1020(3):213-231 ORMEJOHNSON NR DISTINCTIVE PROPERTIES OF ADRENAL-CORTEX MITOCHONDRIA	65	8
3238	8	6952 1990 BRITISH JOURNAL OF CANCER 61(2):195-206 LAW MR GENETIC PREDISPOSITION TO LUNG-CANCER	64	8
3239	9	6999 1990 CLINICAL PHARMACOKINETICS 19(5):400-415 YEE GC; MCGUIRE TR PHARMACOKINETIC DRUG-INTERACTIONS WITH CYCLOSPORINE .2.	79	8
3240	6	7021 1990 DRUG METABOLISM AND DISPOSITION 18(3):356-361 VERONESE ME; MCMANUS ME; LAUPATTARAKASEM P; MINERS JO; BIRKETT DJ TOLBUTAMIDE HYDROXYLATION BY HUMAN, RABBIT AND RAT-LIVER MICROSOMES AND BY PURIFIED FORMS OF CYTOCHROME-P-450	32	8
3241	11	7041 1990 ENDOCRINOLOGY 126(2):712-720 WAXMAN DJ; MORRISSEY JJ; MACLEOD JN; SHAPIRO BH DEPLETION OF SERUM GROWTH-HORMONE IN ADULT FEMALE RATS BY NEONATAL MONOSODIUM GLUTAMATE TREATMENT WITHOUT LOSS OF FEMALE- SPECIFIC HEPATIC ENZYMES-P450 2D (IIC12) AND STEROID 5-ALPHA- REDUCTASE	32	8
3242	5	7084 1990 GENOMICS 7(3):445-448 MILES JS; MOSS JE; MEEHAN RR; WOLF CR CLOSE LINKAGE OF THE CYTOCHROME-P450IIA GENE SUBFAMILY (CYP2A) TO CYP2B AND COH ON MOUSE CHROMOSOME-7	15	8
3243	5	7114 1990 JOURNAL OF BIOCHEMISTRY 107(6):810-816 ZENNO S; HATTORI M; MISUMI Y; YUBISUI T; SAKAKI Y MOLECULAR-CLONING OF A CDNA-ENCODING RAT NADH CYTOCHROME-B5 REDUCTASE AND THE CORRESPONDING GENE	20	8
3244	9	7148 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(33):20228-20233 MATHEW PA; MASON JI; TRANT JM; SANDERS D; WATERMAN MR AMINO-ACID SUBSTITUTIONS PHE-66-]LEU AND SER-126-]PRO ABOLISH CORTISOL AND ALDOSTERONE SYNTHESIS BY BOVINE CYTOCHROME-P45011- BETA	21	8
3245	16	7149 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(33):20602-20608 HANUKOGLU I; FEUCHTWANGER R; HANUKOGLU A MECHANISM OF CORTICOTROPIN AND CAMP INDUCTION OF MITOCHONDRIAL CYTOCHROME-P450 SYSTEM ENZYMES IN ADRENAL-CORTEX CELLS	46	8
3246	5	7150 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(35):21709-21713 STRITTMATTER P; HACKETT CS; KORZA G; OZOLS J CHARACTERIZATION OF THE COVALENT CROSS-LINKS OF THE ACTIVE- SITES OF AMIDINATED CYTOCHROME-B5 AND NADH - CYTOCHROME-B5 REDUCTASE	22	8
3247	1	7166 1990 JOURNAL OF CLINICAL INVESTIGATION 86(6):2054-2061 KRAHENBUHL S; RAY DB; STABLER SP; ALLEN RH; BRASS EP INCREASED HEPATIC MITOCHONDRIAL CAPACITY IN RATS WITH HYDROXY- COBALAMIN[C-LACTAM]-INDUCED METHYLMALONIC ACIDURIA	16	8
3248	8	7172 1990 JOURNAL OF INVESTIGATIVE DERMATOLOGY 94(1):86-93 GUO JF; BROWN R; ROTHWELL CE; BERNSTEIN IA LEVELS OF CYTOCHROME P-450-MEDIATED ARYL-HYDROCARBON HYDROXYLASE (AHH) ARE HIGHER IN DIFFERENTIATED THAN IN GERMINATIVE CUTANEOUS KERATINOCYTES	28	8
3249	13	7225 1990 MOLECULAR AND CELLULAR ENDOCRINOLOGY 73(1):73-80 MATHEW PA; MASON JI; TRANT JM; WATERMAN MR INCORPORATION OF STEROIDOGENIC PATHWAYS WHICH PRODUCE CORTISOL AND ALDOSTERONE FROM CHOLESTEROL INTO NONSTEROIDOGENIC CELLS	11	8
3250	11	7229 1990 MOLECULAR ENDOCRINOLOGY 4(6):893-898 HU MC; CHUNG BC EXPRESSION OF HUMAN 21-HYDROXYLASE (P450C21) IN BACTERIAL AND MAMMALIAN-CELLS - A SYSTEM TO CHARACTERIZE NORMAL AND MUTANT ENZYMES	19	8
3251	1	7335 1991 ADVANCES IN PROSTAGLANDIN THROMBOXANE AND LEUKOTRIENE RESEARCH 21():205-208 ROMERO MF; MADHUN ZT; HOPFER U; DOUGLAS JG AN EPOXYGENASE METABOLITE OF ARACHIDONIC-ACID 5,6 EPOXY- EICOSATRIENOIC ACID MEDIATES ANGIOTENSIN-INDUCED NATRIURESIS IN PROXIMAL TUBULAR EPITHELIUM	14	8
3252	15	7379 1991 ARCHIVES OF TOXICOLOGY 65(1):45-51 UENG TH; TSAI JN; JU JM; UENG YF; IWASAKI M; GUENGERICH FP EFFECTS OF ACETONE ADMINISTRATION ON CYTOCHROME-P-450-DEPENDENT MONOOXYGENASES IN HAMSTER LIVER, KIDNEY, AND LUNG	23	8
3253	7	7400 1991 BIOCHEMICAL PHARMACOLOGY 41(2):177-184 GERVASI PG; LONGO V; NALDI F; PANATTONI G; URSINO F XENOBIOTIC-METABOLIZING ENZYMES IN HUMAN RESPIRATORY NASAL- MUCOSA	37	8
3254	3	7472 1991 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 31(6):649-654 PAGE MA; BOUTAGY JS; SHENFIELD GM A SCREENING-TEST FOR SLOW METABOLIZERS OF TOLBUTAMIDE	23	8
3255	7	7522 1991 DNA AND CELL BIOLOGY 10(1):33-39 TROTTIER Y; WAITHE WI; ANDERSON A RAT-LIVER CYTOCHROME-P450IA2 SYNTHESIZED BY TRANSFECTED COS-1 CELLS EFFICIENTLY ACTIVATES FOOD-DERIVED PROMUTAGENS	12	8
3256	2	7551 1991 ENVIRONMENTAL HEALTH PERSPECTIVES 93():205-209 RAO MS; REDDY JK AN OVERVIEW OF PEROXISOME PROLIFERATOR-INDUCED HEPATOCARCINOGENESIS	75	8
3257	5	7612 1991 JOURNAL OF BIOCHEMISTRY 110(4):641-647 SAGAMI I; OHMACHI T; FUJII H; KIKUCHI H; WATANABE M HAMSTER CYTOCHROME-P-450 IA GENE FAMILY, P-450IA1 AND P-450IA2 IN LUNG AND LIVER - CDNA CLONING AND SEQUENCE-ANALYSIS	15	8
3258	3	7640 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(31):20998-21003 KRAHENBUHL S; CHANG M; BRASS EP; HOPPEL CL DECREASED ACTIVITIES OF UBIQUINOL-FERRICYTOCHROME-C OXIDOREDUCTASE (COMPLEX-III) AND FERROCYTOCHROME-C-OXYGEN OXIDOREDUCTASE (COMPLEX-IV) IN LIVER-MITOCHONDRIA FROM RATS WITH HYDROXYCOBALAMIN[C-LACTAM]-INDUCED METHYLMALONIC ACIDURIA	32	8
3259	14	7708 1991 METHODS IN ENZYMOLOGY 206():353-364 GIBSON GG; LAKE BG INDUCTION PROTOCOLS FOR THE CYTOCHROME P450IVA SUBFAMILY IN ANIMALS AND PRIMARY HEPATOCYTE CULTURES	16	8
3260	8	7714 1991 METHODS IN ENZYMOLOGY 206():523-529 WASKELL LA; VIGNE JL; VERGERES G SITE OF ACTION OF SUBSTRATES REQUIRING CYTOCHROME-B5 FOR OXIDATION BY CYTOCHROME P450	16	8
3261	9	7725 1991 MOLECULAR ENDOCRINOLOGY 5(12):2037-2045 BIASON A; MANTERO F; SCARONI C; SIMPSON ER; WATERMAN MR DELETION WITHIN THE CYP17-GENE TOGETHER WITH INSERTION OF FOREIGN DNA IS THE CAUSE OF COMBINED COMPLETE 17 ALPHA- HYDROXYLASE/17,20-LYASE DEFICIENCY IN AN ITALIAN PATIENT	22	8
3262	14	7732 1991 MOLECULAR PHARMACOLOGY 40(2):203-210 KOCAREK TA; SCHUETZ EG; GUZELIAN PS SELECTIVE INDUCTION OF CYTOCHROME-P450E BY KEPONE (CHLORDECONE) IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	22	8
3263	2	7827 1992 AMERICAN JOURNAL OF HUMAN GENETICS 51(3):666-672 HARADA N; OGAWA H; SHOZU M; YAMADA K GENETIC-STUDIES TO CHARACTERIZE THE ORIGIN OF THE MUTATION IN PLACENTAL AROMATASE DEFICIENCY	26	8
3264	8	7858 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(1):215-222 OBACH RS; SPINK DC; CHEN N; KAMINSKY LS AZIDOWARFARIN PHOTOAFFINITY PROBES OF PURIFIED RAT-LIVER CYTOCHROME-P4501A1	14	8
3265	7	7859 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(2):454-460 VINCENT SH; KARANAM BV; PAINTER SK; CHIU SHL INVITRO METABOLISM OF FK-506 IN RAT, RABBIT, AND HUMAN LIVER- MICROSOMES - IDENTIFICATION OF A MAJOR METABOLITE AND OF CYTOCHROME P450-3A AS THE MAJOR ENZYMES RESPONSIBLE FOR ITS METABOLISM	76	8
3266	6	7875 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 297(2):228-238 CORREIA MA; DAVOLL SH; WRIGHTON SA; THOMAS PE DEGRADATION OF RAT-LIVER CYTOCHROMES-P450 3A AFTER THEIR INACTIVATION BY 3,5-DICARBETHOXY-2,6-DIMETHYL-4-ETHYL-1,4- DIHYDROPYRIDINE - CHARACTERIZATION OF THE PROTEOLYTIC SYSTEM	34	8
3267	10	7891 1992 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 184(3):1490-1495 CULLIN C 2 DISTINCT SEQUENCES CONTROL THE TARGETING AND ANCHORING OF THE MOUSE P450 1A1 INTO THE YEAST ENDOPLASMIC-RETICULUM MEMBRANE	13	8
3268	12	7917 1992 BIOCHEMICAL PHARMACOLOGY 43(10):2169-2180 PARKINSON A; CLEMENT RP; CASCIANO CN; CAYEN MN EVALUATION OF LORATADINE AS AN INDUCER OF LIVER MICROSOMAL CYTOCHROME-P450 IN RATS AND MICE	30	8
3269	19	7930 1992 BIOCHEMICAL PHARMACOLOGY 44(12):2307-2314 PIRMOHAMED M; KITTERINGHAM NR; BRECKENRIDGE AM; PARK BK THE EFFECT OF ENZYME-INDUCTION ON THE CYTOCHROME-P450-MEDIATED BIOACTIVATION OF CARBAMAZEPINE BY MOUSE-LIVER MICROSOMES	36	8
3270	10	7937 1992 BIOCHEMISTRY 31(21):5060-5067 YAO EF; DENISON MS DNA-SEQUENCE DETERMINANTS FOR BINDING OF TRANSFORMED AH- RECEPTOR TO A DIOXIN-RESPONSIVE ENHANCER	70	8
3271	13	8084 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 208(3):739-746 TSUNEOKA Y; MATSUO Y; HIGUCHI R; ICHIKAWA Y CHARACTERIZATION OF THE CYTOCHROME P-450IID SUBFAMILY IN BOVINE LIVER - NUCLEOTIDE-SEQUENCES AND MICROHETEROGENEITY	13	8
3272	5	8128 1992 GENOMICS 14(1):153-161 COHEN JC; CALI JJ; JELINEK DF; MEHRABIAN M; SPARKES RS; LUSIS AJ; RUSSELL DW; HOBBS HH CLONING OF THE HUMAN CHOLESTEROL-7 ALPHA-HYDROXYLASE GENE (CYP7) AND LOCALIZATION TO CHROMOSOME 8Q11-Q12	53	8
3273	4	8133 1992 HEPATOLOGY 15(6):1167-1172 KRAHENBUHL S; KRAHENBUHLGLAUSER S; STUCKI J; GEHR P; REICHEN J STEREOLOGICAL AND FUNCTIONAL-ANALYSIS OF LIVER-MITOCHONDRIA FROM RATS WITH SECONDARY BILIARY-CIRRHOSIS - IMPAIRED MITOCHONDRIAL METABOLISM AND INCREASED MITOCHONDRIAL CONTENT PER HEPATOCYTE	32	8
3274	6	8158 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(4):2519-2523 STRITTMATTER P; KITTLER JM; COGHILL JE; OZOLS J CHARACTERIZATION OF LYSYL RESIDUES OF NADH-CYTOCHROME-B5 REDUCTASE IMPLICATED IN CHARGE-PAIRING WITH ACTIVE-SITE CARBOXYL RESIDUES OF CYTOCHROME-B5 BY SITE-DIRECTED MUTAGENESIS OF AN EXPRESSION VECTOR FOR THE FLAVOPROTEIN	21	8
3275	3	8218 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 261(3):1195-1199 MINISCALCO A; LUNDAHL J; REGARDH CG; EDGAR B; ERIKSSON UG INHIBITION OF DIHYDROPYRIDINE METABOLISM IN RAT AND HUMAN LIVER-MICROSOMES BY FLAVONOIDS FOUND IN GRAPEFRUIT JUICE	92	8
3276	15	8222 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 263(1):360-367 LEEDER JS; RILEY RJ; COOK VA; SPIELBERG SP HUMAN ANTI-CYTOCHROME-P450 ANTIBODIES IN AROMATIC ANTICONVULSANT-INDUCED HYPERSENSITIVITY REACTIONS	55	8
3277	12	8231 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 42(5):499-508 KADDOURI M; BRASSET N; ALVINERIE M; EECKHOUTTE C; BONFILS C; DERANCOURT J; GALTIER P ONTOGENIC DEVELOPMENT OF LIVER PROGESTERONE METABOLISM IN FEMALE SHEEP - CONTRIBUTION OF CYTOCHROME-P4502B AND P4503A- SUBFAMILIES	19	8
3278	4	8257 1992 MARINE ENVIRONMENTAL RESEARCH 34(1-4):97-101 ELSKUS AA; PRUELL R; STEGEMAN JJ ENDOGENOUSLY-MEDIATED, PRETRANSLATIONAL SUPPRESSION OF CYTOCHROME-P4501A IN PCB-CONTAMINATED FLOUNDER	29	8
3279	5	8259 1992 MARINE ENVIRONMENTAL RESEARCH 34(1-4):139-145 HAASCH ML; QUARDOKUS EM; SUTHERLAND LA; GOODRICH MS; PRINCE R; COOPER KR; LECH JJ CYP1A1 PROTEIN AND MESSENGER-RNA IN TELEOSTS AS AN ENVIRONMENTAL BIOINDICATOR - LABORATORY AND ENVIRONMENTAL- STUDIES	22	8
3280	7	8263 1992 MOLECULAR AND CELLULAR BIOLOGY 12(5):2124-2134 GITELMAN SE; BRISTOW J; MILLER WL MECHANISM AND CONSEQUENCES OF THE DUPLICATION OF THE HUMAN C4/P450C21/GENE X-LOCUS	63	8
3281	12	8379 1993 ANNUAL REVIEW OF NUTRITION 13():383-403 FORSTER RE; ESTABROOK RW IS OXYGEN AN ESSENTIAL NUTRIENT	8	8
3282	9	8406 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 304(2):454-463 RYAN R; GRIMM SW; KEDZIE KM; HALPERT JR; PHILPOT RM CLONING, SEQUENCING, AND FUNCTIONAL-STUDIES OF PHENOBARBITAL- INDUCIBLE FORMS OF CYTOCHROME-P450-2B AND CYTOCHROME-P450-4B EXPRESSED IN RABBIT KIDNEY	16	8
3283	12	8480 1993 BIOCHEMICAL PHARMACOLOGY 46(11):1945-1951 LONGO V; INGELMANSUNDBERG M ACETONE-DEPENDENT REGULATION OF CYTOCHROMES P4502E1 AND P4502B1 IN RAT NASAL-MUCOSA	23	8
3284	16	8488 1993 BIOCHEMISTRY 32(8):1951-1957 KRAINEV AG; SHIMIZU T; ISHIGOOKA M; HIROYA K; HATANO M CHIRAL RECOGNITION AT CYTOCHROME-P450 1A2 ACTIVE-SITE - EFFECTS OF MUTATIONS AT THE PUTATIVE DISTAL SITE ON THE BINDINGS OF ASYMMETRICAL AXIAL LIGANDS	13	8
3285	7	8510 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1161(2-3):124-130 TSUJITA M; ICHIKAWA Y SUBSTRATE-BINDING REGION OF CYTOCHROME P-450SCC (P-450 XIA1) - IDENTIFICATION AND PRIMARY STRUCTURE OF THE CHOLESTEROL BINDING REGION IN CYTOCHROME P-450SCC	13	8
3286	22	8511 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1164(2):124-132 KEDZIE KM; GRIMM SW; CHEN F; HALPERT JR HYBRID ENZYMES FOR STRUCTURE-FUNCTION ANALYSIS OF CYTOCHROME-P- 450-2B11	13	8
3287	8	8512 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1166(2-3):258-263 OLIW EH BIS-ALLYLIC HYDROXYLATION OF LINOLEIC-ACID AND ARACHIDONIC-ACID BY HUMAN HEPATIC MONOOXYGENASES	17	8
3288	4	8532 1993 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 35(3):331-334 SKJELBO E; GRAM LF; BROSEN K THE N-DEMETHYLATION OF IMIPRAMINE CORRELATES WITH THE OXIDATION OF S-MEPHENYTOIN (S/R-RATIO) - A POPULATION STUDY	31	8
3289	8	8534 1993 BRITISH JOURNAL OF PHARMACOLOGY 110(1):482-490 HERMANS JJR; THIJSSEN HHW HUMAN LIVER MICROSOMAL METABOLISM OF THE ENANTIOMERS OF WARFARIN AND ACENOCOUMAROL - P450 ISOZYME DIVERSITY DETERMINES THE DIFFERENCES IN THEIR PHARMACOKINETICS	38	8
3290	5	8541 1993 CANCER RESEARCH 53(15):3541-3546 ALBIN N; MASSAAD L; TOUSSAINT C; MATHIEU MC; MORIZET J; PARISE O; GOUYETTE A; CHABOT GG MAIN DRUG-METABOLIZING ENZYME-SYSTEMS IN HUMAN BREAST-TUMORS AND PERITUMORAL TISSUES	36	8
3291	5	8559 1993 CHEMICAL RESEARCH IN TOXICOLOGY 6(1):38-45 CHAN WK; SUI Z; DEMONTELLANO PRO DETERMINANTS OF PROTEIN MODIFICATION VERSUS HEME ALKYLATION - INACTIVATION OF CYTOCHROME-P450 1A1 BY 1-ETHYNYLPYRENE AND PHENYLACETYLENE	18	8
3292	19	8616 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 214(3):735-745 MAPOLES J; BERTHOU F; ALEXANDER A; SIMON F; MENEZ JF MAMMALIAN PC-12 CELL GENETICALLY-ENGINEERED FOR HUMAN CYTOCHROME-P450 2E1 EXPRESSION	26	8
3293	9	8646 1993 HEPATOLOGY 17(2):230-235 CRAIG PI; TAPNER M; FARRELL GC INTERFERON SUPPRESSES ERYTHROMYCIN METABOLISM IN RATS AND HUMAN-SUBJECTS	31	8
3294	11	8689 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(17):12919-12924 BRISTOW J; GITELMAN SE; TEE MK; STAELS B; MILLER WL ABUNDANT ADRENAL-SPECIFIC TRANSCRIPTION OF THE HUMAN P450C21A PSEUDOGENE	46	8
3295	11	8694 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17628-17633 GRANT DF; STORMS DH; HAMMOCK BD MOLECULAR-CLONING AND EXPRESSION OF MURINE LIVER SOLUBLE EPOXIDE HYDROLASE	43	8
3296	7	8711 1993 JOURNAL OF CLINICAL INVESTIGATION 91(6):2488-2496 LEITERSDORF E; RESHEF A; MEINER V; LEVITZKI R; SCHWARTZ SP; DANN EJ; BERKMAN N; CALI JJ; KLAPHOLZ L; BERGINER VM FRAMESHIFT AND SPLICE-JUNCTION MUTATIONS IN THE STEROL 27- HYDROXYLASE GENE CAUSE CEREBROTENDINOUS XANTHOMATOSIS IN JEWS OF MOROCCAN ORIGIN	84	8
3297	38	8735 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 267(2):758-764 KNICKLE LC; WEBB CD; HOUSE AA; BEND JR MECHANISM-BASED INACTIVATION OF CYTOCHROME P450-1A1 BY N- ARALKYL-1-AMINOBENZOTRIAZOLES IN GUINEA-PIG KIDNEY IN-VIVO AND IN-VITRO - MINIMAL EFFECTS ON METABOLISM OF ARACHIDONIC-ACID BY RENAL P450-DEPENDENT MONOOXYGENASES	13	8
3298	7	8778 1993 MOLECULAR ENDOCRINOLOGY 7(12):1617-1624 AMARNEH B; CORBIN CJ; PETERSON JA; SIMPSON ER; GRAHAMLORENCE S FUNCTIONAL DOMAINS OF HUMAN AROMATASE CYTOCHROME-P450 CHARACTERIZED BY LINEAR ALIGNMENT AND SITE-DIRECTED MUTAGENESIS	31	8
3299	3	8798 1993 PHARMACOGENETICS 3(1):40-44 LAWTON MP; PHILPOT RM MOLECULAR-GENETICS OF THE FLAVIN-DEPENDENT MONOOXYGENASES	17	8
3300	8	8876 1993 XENOBIOTICA 23(2):169-179 JAPENGA AC; DAVIES S; PRICE RJ; LAKE BG EFFECT OF TREATMENT WITH PYRAZINE AND SOME DERIVATIVES ON CYTOCHROME-P450 AND SOME ENZYME-ACTIVITIES IN RAT-LIVER	17	8

#	Cited nodes	Nodes / Authors	GCS	LCS
3301	11	8916 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 310(2):452-459 OLEARY KA; BECK TW; KASPER CB NADPH CYTOCHROME-P-450 OXIDOREDUCTASE GENE - IDENTIFICATION AND CHARACTERIZATION OF THE PROMOTER REGION	16	8
3302	19	8933 1994 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 27(3):205-216 ZHANG ML; SCOTT JG CYTOCHROME B(5) INVOLVEMENT IN CYTOCHROME-P450 MONOOXYGENASE ACTIVITIES IN-HOUSE FLY MICROSOMES	15	8
3303	6	8953 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 205(1):631-637 SALONPAA P; PELKONEN O; KOJO A; PASANEN M; NEGISHI M; RAUNIO H CYTOCHROME P4502A5 EXPRESSION AND INDUCIBILITY BY PHENOBARBITAL IS MODULATED BY CAMP IN MOUSE PRIMARY HEPATOCYTES	25	8
3304	13	8995 1994 BIOCHEMISTRY 33(40):12056-12062 BLACK SD; MARTIN ST EVIDENCE FOR CONFORMATIONAL DYNAMICS AND MOLECULAR AGGREGATION IN CYTOCHROME-P450-102 (BM-3)	10	8
3305	7	9058 1994 CLINICAL PHARMACOLOGY & THERAPEUTICS 55(5):518-527 NIELSEN KK; BROSEN K; HANSEN MGJ; GRAM LF SINGLE-DOSE KINETICS OF CLOMIPRAMINE - RELATIONSHIP TO THE SPARTEINE AND S-MEPHENYTOIN OXIDATION POLYMORPHISMS	59	8
3306	10	9066 1994 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 107(3):405-414 ARINC E; SEN A EFFECTS OF IN-VIVO BENZO(A)PYRENE TREATMENT ON LIVER MICROSOMAL MIXED-FUNCTION OXIDASE ACTIVITIES OF GILTHEAD SEABREAM (SPARUS- AURATA)	11	8
3307	7	9086 1994 DRUG METABOLISM AND DISPOSITION 22(3):352-357 RING BJ; PARLI CJ; GEORGE MC; WRIGHTON SA IN-VITRO METABOLISM OF ZATOSETRON - INTERSPECIES COMPARISON AND ROLE OF CYP 3A	13	8
3308	8	9140 1994 FOOD AND CHEMICAL TOXICOLOGY 32(4):387-390 VANIERSEL M; WALTERS DG; PRICE PJ; LOVELL DP; LAKE BG SEX AND STRAIN DIFFERENCES IN MOUSE HEPATIC-MICROSOMAL COUMARIN 7-HYDROXYLASE ACTIVITY	16	8
3309	3	9174 1994 JOURNAL OF BIOCHEMICAL TOXICOLOGY 9(6):297-304 POON R; CHU I; LECAVALIER P; BERGMAN A; VILLENEUVE DC URINARY ASCORBIC-ACID - HPLC DETERMINATION AND APPLICATION AS A NONINVASIVE BIOMARKER OF HEPATIC RESPONSE	20	8
3310	9	9214 1994 JOURNAL OF CHEMICAL ECOLOGY 20(8):1893-1906 DANIELSON PB; FRANK MR; FOGLEMAN JC COMPARISON OF LARVAL AND ADULT P-450 ACTIVITY LEVELS FOR ALKALOID METABOLISM IN DESERT DROSOPHILA	10	8
3311	14	9215 1994 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 652(2):123-136 YAMANE M; ABE A; YAMANE S HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY THERMOSPRAY MASS- SPECTROMETRY OF EPOXY POLYUNSATURATED FATTY-ACIDS AND EPOXYHYDROXY POLYUNSATURATED FATTY-ACIDS FROM AN INCUBATION MIXTURE OF RAT-TISSUE HOMOGENATE	11	8
3312	19	9221 1994 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 79(1):160-164 FARDELLA CE; HUM DW; HOMOKI J; MILLER WL POINT MUTATION OF ARG440 TO HIS IN CYTOCHROME P450C17 CAUSES SEVERE 17-ALPHA-HYDROXYLASE DEFICIENCY	36	8
3313	16	9250 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 269(3):1130-1135 DAIKH BE; LAETHEM RM; KOOP DR STEREOSELECTIVE EPOXIDATION OF ARACHIDONIC-ACID BY CYTOCHROME P-450S 2CAA AND 2C2	10	8
3314	10	9303 1994 MOLECULAR PHARMACOLOGY 45(6):1287-1295 BOURDI M; TINEL M; BEAUNE PH; PESSAYRE D INTERACTIONS OF DIHYDRALAZINE WITH CYTOCHROMES-P4501A - A POSSIBLE EXPLANATION FOR THE APPEARANCE OF ANTI-CYTOCHROME- P4501A2 AUTOANTIBODIES	32	8
3315	12	9343 1994 PLANT SCIENCE 96(1-2):129-136 MANGOLD U; EICHEL J; BATSCHAUER A; LANZ T; KAISER T; SPANGENBERG G; WERCKREICHHART D; SCHRODER J GENE AND CDNA FOR PLANT CYTOCHROME-P450 PROTEINS (CYP72 FAMILY) FROM CATHARANTHUS-ROSEUS, AND TRANSGENIC EXPRESSION OF THE GENE AND A CDNA IN TOBACCO AND ARABIDOPSIS-THALIANA	13	8
3316	7	9438 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 318(2):333-339 PENG HM; RANER GM; VAZ ADN; COON MJ OXIDATIVE CLEAVAGE OF ESTERS AND AMIDES TO CARBONYL PRODUCTS BY CYTOCHROME-P450	17	8
3317	12	9489 1995 BIOCHEMICAL PHARMACOLOGY 49(7):873-881 GEORGE J; LIDDLE C; MURRAY M; BYTH K; FARRELL GC PRETRANSLATIONAL REGULATION OF CYTOCHROME-P450 GENES IS RESPONSIBLE FOR DISEASE-SPECIFIC CHANGES OF INDIVIDUAL P450 ENZYMES AMONG PATIENTS WITH CIRRHOSIS	31	8
3318	32	9560 1995 CANCER SURVEYS 25():27-65 Smith G; Stanley LA; Sim E; Strange RC; Wolf CR Metabolic polymorphisms and cancer susceptibility	124	8
3319	15	9623 1995 DRUG METABOLISM AND DISPOSITION 23(10):1163-1174 MACHINIST JM; MAYER MD; SHET MS; FERRERO JL; RODRIGUES AD IDENTIFICATION OF THE HUMAN LIVER CYTOCHROME-P450 ENZYMES INVOLVED IN THE METABOLISM OF ZILEUTON (ABT-077) AND ITS N- DEHYDROXYLATED METABOLITE, ABBOTT-66193	17	8
3320	11	9663 1995 EUROPEAN JOURNAL OF PHARMACOLOGY-ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY SECTION 293(2):123-131 SCHMALIX WA; BARRENSCHEEN M; LANDSIEDEL R; JANZOWSKI C; EISENBRAND G; GONZALEZ F; ELIASSON E; INGELMANSUNDBERG M; PERCHERMEIER M; GREIM H; DOEHMER J STABLE EXPRESSION OF HUMAN CYTOCHROME-P450 2E1 IN V79 CHINESE- HAMSTER CELLS	20	8
3321	4	9703 1995 INSECT MOLECULAR BIOLOGY 4(3):135-140 TOMITA T; LIU N; SMITH FF; SRIDHAR P; SCOTT JG MOLECULAR MECHANISMS INVOLVED IN INCREASED EXPRESSION OF A CYTOCHROME-P450 RESPONSIBLE FOR PYRETHROID RESISTANCE IN THE HOUSEFLY, MUSCA-DOMESTICA	31	8
3322	4	9724 1995 JOURNAL OF BIOLOGICAL CHEMISTRY 270(27):16114-16121 PALMER CNA; HSU MH; GRIFFIN KJ; JOHNSON EF NOVEL SEQUENCE DETERMINANTS IN PEROXISOME PROLIFERATOR SIGNALING	115	8
3323	7	9746 1995 JOURNAL OF EXPERIMENTAL ZOOLOGY 272(1):25-33 TRANT JM ISOLATION AND CHARACTERIZATION OF THE CDNA-ENCODING THE SPINY DOGFISH SHARK (SQUALUS-ACANTHIAS) FORM OF CYTOCHROME P450C17	12	8
3324	12	9817 1995 MOLECULAR PHARMACOLOGY 47(4):677-685 CHUNG I; BRESNICK E REGULATION OF THE CONSTITUTIVE EXPRESSION OF THE HUMAN CYP1A2 GENE - CIS-ELEMENTS AND THEIR INTERACTIONS WITH PROTEINS	16	8
3325	14	9824 1995 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 353(1):116-121 Busse D; Cosme J; Beaune P; Kroemer HK; Eichelbaum M Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans	38	8
3326	6	9856 1995 PLANT PHYSIOLOGY AND BIOCHEMISTRY 33(6):751-757 LESOT A; HASENFRATZ MP; BATARD Y; DURST F; BENVENISTE I 2 MESSENGER-RNAS ARE ENCODING FOR NADPH-CYTOCHROME P450 REDUCTASES IN HELIANTHUS-TUBEROSUS TUBER TISSUES	11	8
3327	51	9915 1996 ADVANCED DRUG DELIVERY REVIEWS 22(1-2):105-132 Maurel P The use of adult human hepatocytes in primary culture and other in vitro systems to investigate drug metabolism in man	46	8
3328	20	9949 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 327(1):167-173 Liu JP; He YA; Halpert JR Role of residue 480 in substrate specificity of cytochrome P450 2B5 and 2B11	15	8
3329	15	9964 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 330(1):97-109 Menzel R; Kargel E; Vogel F; Bottcher C; Schunck WH Topogenesis of a microsomal cytochrome P450 and induction of endoplasmic reticulum membrane proliferation in Saccharomyces cerevisiae	16	8
3330	4	9969 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 331(1):79-86 Nirodi CS; Sultana S; Ram N; Prabhu L; Padmanaban G Involvement of synthesis and phosphorylation of nuclear protein factors that bind to the positive cis-acting element in the transcriptional activation of the CYP2B1/B2 gene by phenobarbitone in vivo	20	8
3331	8	10049 1996 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 38(4):829-838 Shumantseva VV; Uvarov VY; Byakova OE; Archakov AI Reductase and oxygenase activities of semisynthetic flavocytochromes based on cytochrome P450 2B4.	11	8
3332	3	10176 1996 EUROPEAN JOURNAL OF BIOCHEMISTRY 235(3):660-669 Jung C; Ristau O; Schulze H; Sligar SG The CO stretching mode infrared spectrum of substrate-free cytochrome P-450(cam)-CO - The effect of solvent conditions, temperature, and pressure	20	8
3333	23	10223 1996 INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY 11():31-61 Lane RM Pharmacokinetic drug interaction potential of selective serotonin reuptake inhibitors	53	8
3334	18	10237 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(14):8028-8033 Bottner B; Schrauber H; Bernhardt R Engineering a mineralocorticoid- to a glucocorticoid- synthesizing cytochrome P450	14	8
3335	17	10251 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(42):26209-26213 Sakaki T; Kominami S; Hayashi K; AkiyoshiShibata M; Yabusaki Y Molecular engineering study on electron transfer from NADPH- P450 reductase to rat mitochondrial P450c27 in yeast microsomes	14	8
3336	3	10256 1996 JOURNAL OF BIOLOGICAL CHEMISTRY 271(47):29922-29927 White JA; Guo YD; Baetz K; BeckettJones B; Bonasoro J; Hsu KE; Dilworth FJ; Jones G; Petkovich M Identification of the retinoic acid-inducible all-trans- retinoic acid 4-hydroxylase	118	8
3337	11	10278 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(11):3843-3849 Agarwal VR; Bulun SE; Leitch M; Rohrich R; Simpson ER Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients	61	8
3338	29	10292 1996 JOURNAL OF ENDOCRINOLOGY 150():S129-S147 Waxman DJ Role of metabolism in the activation of dehydroepiandrosterone as a peroxisome proliferator	29	8
3339	4	10316 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(3):1195-1199 Fulton D; Balazy M; McGiff JC; Quilley J Possible contribution of platelet cyclooxygenase to the renal vascular action of 5,6-epoxyeicosatrienoic acid	14	8
3340	18	10497 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 340(2):231-238 Sevrioukova I; Truan G; Peterson JA Reconstitution of the fatty acid hydroxylase activity of cytochrome P450BM-3 utilizing its functional domains	10	8
3341	17	10542 1997 BIOCHEMICAL JOURNAL 321():857-863 LeeRobichaud P; Kaderbhai MA; Kaderbhai N; Wright JN; Akhtar M Interaction of human CYP17 (P-450(17 alpha), 17 alpha- hydroxylase-17,20-lyase) with cytochrome b(5): Importance of the orientation of the hydrophobic domain of cytochrome b(5)	14	8
3342	26	10585 1997 BIOLOGY OF REPRODUCTION 56(4):789-799 Conley AJ; Bird IM The role of cytochrome P450 17 alpha-hydroxylase and 3 beta- hydroxysteroid dehydrogenase in the integration of gonadal and adrenal steroidogenesis via the Delta 5 and Delta 4 pathways of steroidogenesis in mammals	52	8
3343	1	10589 1997 BRITISH JOURNAL OF CANCER 76(9):1181-1183 vanAsperen J; vanTellingen O; Sparreboom A; Schinkel AH; Borst P; Nooijen WJ; Beijnen JH Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833	70	8
3344	35	10670 1997 DRUG METABOLISM REVIEWS 29(3):747-799 DeGroot MJ; Vermeulen NPE Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes	19	8
3345	11	10791 1997 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS 37(2):67-73 Purdon MP; LehmanMcKeeman LD Improved high-performance liquid chromatographic procedure for the separation and quantification of hydroxytestosterone metabolites	11	8
3346	11	10825 1997 MOLECULAR AND CELLULAR ENDOCRINOLOGY 131(1):39-49 Bassett MH; McCarthy JL; Waterman MR; Sliter TJ Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila	17	8
3347	19	10832 1997 MOLECULAR PHARMACOLOGY 51(5):741-754 SchmiedlinRen P; Thummel KE; Fisher JM; Paine MF; Lown KS; Watkins PB Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1 alpha,25-dihydroxyvitamin D-3	81	8
3348	7	10878 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(6):2133-2138 Oprea TI; Hummer G; Garcia AE Identification of a functional water channel in cytochrome P450 enzymes	33	8
3349	28	10888 1997 PROTEIN EXPRESSION AND PURIFICATION 9(3):346-354 Parikh A; Guengerich FP Expression, purification, and characterization of a catalytically active human cytochrome P450 1A2:Rat NADPH- cytochrome P450 reductase fusion protein	10	8
3350	29	10893 1997 RECENT PROGRESS IN HORMONE RESEARCH, PROCEEDINGS OF THE 1996 CONFERENCE, VOL 52 52():185-214 Simpson ER; Zhao Y; Agarwal VR; Michael MD; Bulun SE; Hinshelwood MM; Graham-Lorence S; Sun TJ; Fisher CR; Qin KN; Mendelson CR Aromatase expression in health and disease	99	8
3351	12	10911 1997 TOXICOLOGY AND APPLIED PHARMACOLOGY 146(1):134-143 Gu J; Walker VE; Lipinskas TW; Walker DM; Ding XX Intraperitoneal administration of coumarin causes tissue- selective depletion of cytochromes P450 and cytotoxicity in the olfactory mucosa	18	8
3352	9	10962 1998 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 64(10):3784-3790 Schneider S; Wubbolts MG; Sanglard D; Witholt B Biocatalyst engineering by assembly of fatty acid transport and oxidation activities for in vivo application of cytochrome P- 450(BM-3) monooxygenase	9	8
3353	22	10971 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 350(2):333-339 He YQ; Harlow GR; Szklarz GD; Halpert JR Structural determinants of progesterone hydroxylation by cytochrome P450 2B5: The role of nonsubstrate recognition site residues	14	8
3354	15	10990 1998 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 359(2):231-240 Guzov VM; Unnithan GC; Chernogolov AA; Feyereisen R CYP12A1, a mitochondrial cytochrome P450 from the house fly	17	8
3355	11	11048 1998 BIOCHEMISTRY 37(37):12847-12851 Zheng YM; Fisher MB; Yokotani N; Fujii-Kuriyama Y; Rettie AE Identification of a meander region proline residue critical for heme binding to cytochrome P450: Implications for the catalytic function of human CYP4B1	14	8
3356	6	11082 1998 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 45(4):361-368 Kobayashi K; Nakajima M; Chiba K; Yamamoto T; Tani M; Ishizaki T; Kuroiwa Y Inhibitory effects of antiarrhythmic drugs on phenacetin O- deethylation catalysed by human CYP1A2	18	8
3357	24	11271 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(47):31581-31589 Kroetz DL; Yook P; Costet P; Bianchi P; Pineau T Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes	65	8
3358	31	11292 1998 JOURNAL OF LIPID RESEARCH 39(6):1210-1219 Adas F; Berthou F; Picart D; Lozac'h P; Beauge F; Amet Y Involvement of cytochrome P450 2E1 in the (omega-1)- hydroxylation of oleic acid in human and rat liver microsomes	14	8
3359	16	11303 1998 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 285(3):1287-1295 Gu J; Zhang QY; Genter MB; Lipinskas TW; Negishi M; Nebert DW; Ding XX Purification and characterization of heterologously expressed mouse CYP2A5 and CYP2G1: Role in metabolic activation of acetaminophen and 2,6-dichlorobenzonitrile in mouse olfactory mucosal microsomes	17	8
3360	15	11307 1998 JOURNAL OF PROTEIN CHEMISTRY 17(2):121-129 Dai RK; Pincus MR; Friedman FK Molecular modeling of cytochrome P450 2B1: Mode of membrane insertion and substrate specificity	15	8
3361	6	11387 1998 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 95(12):6965-6970 Fisher CR; Graves KH; Parlow AF; Simpson ER Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene	188	8
3362	17	11409 1998 TOXICOLOGY AND APPLIED PHARMACOLOGY 148(2):195-204 Villard PH; Seree EM; Re JL; De Meo M; Barra Y; Attolini L; Dumenil G; Catalin J; Durand A; Lacarelle B Effects of tobacco smoke on the gene expression of the Cyp1a, Cyp2b, Cyp2e, and Cyp3a subfamilies in mouse liver and lung: Relation to single strand breaks of DNA	25	8
3363	27	11426 1998 XENOBIOTICA 28(3):235-268 Lewis DFV; Dickins M; Weaver RJ; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site- directed mutagenesis experiments in the CYP2C subfamily	29	8
3364	18	11450 1999 AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 277(5):H2098-H2108 Weintraub NL; Fang X; Kaduce TL; VanRollins M; Chatterjee P; Spector AA Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids	19	8
3365	13	11473 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 362(1):32-37 Ogino M; Nagata K; Miyata M; Yamazoe Y Hepatocyte nuclear factor 4-mediated activation of rat CYP3A1 gene and its modes of modulation by apolipoprotein AI regulatory protein I and v-ErbA-related protein 3	17	8
3366	12	11479 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 367(1):129-136 Kusano K; Waterman MR; Sakaguchi M; Omura T; Kagawa N Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli	20	8
3367	14	11486 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 369(2):193-196 Kikuta Y; Kusunose E; Ito M; Kusunose M Purification and characterization of recombinant rat hepatic CYP4F1	19	8
3368	53	11593 1999 CRITICAL REVIEWS IN TOXICOLOGY 29(1):59-124 Wormhoudt LW; Commandeur JNM; Vermeulen NPE Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-Transferase, and epoxide hydrolase enzymes: Relevance to xenobiotic metabolism and toxicity	91	8
3369	37	11626 1999 DRUG METABOLISM REVIEWS 31(2):351-364 Schenkman JB; Jansson I Interactions between cytochrome P450 and cytochrome b(5)	17	8
3370	75	11629 1999 DRUG METABOLISM REVIEWS 31(3):719-754 Ekins S; Wrighton SA The role of CYP2B6 in human xenobiotic metabolism	36	8
3371	8	11726 1999 JOURNAL OF CHROMATOGRAPHY A 848(1-2):149-159 Schwaneberg U; Sprauer A; Schmidt-Dannert C; Schmid RD P450 monooxygenase in biotechnology - I. Single-step, large- scale purification method for cytochrome P450BM-3 by anion- exchange chromatography	10	8
3372	16	11790 1999 MOLECULAR ENDOCRINOLOGY 13(1):167-175 Geller DH; Auchus RJ; Miller WL P450c17 mutations R347H and R358Q selectively disrupt 17,20- lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b(5)	33	8
3373	22	11845 1999 PROTEINS-STRUCTURE FUNCTION AND GENETICS 34(3):403-415 Chang YT; Loew GH Homology modeling and substrate binding study of human CYP4A11 enzyme	19	8
3374	13	11855 1999 TOXICOLOGICAL SCIENCES 48(2):151-156 Omiecinski CJ; Remmel RP; Hosagrahara VP Concise review of the cytochrome P450s and their roles in toxicology	27	8
3375	9	12002 2000 CHEMISTRY-A EUROPEAN JOURNAL 6(9):1531-1536 Li QS; Schwaneberg U; Fischer P; Schmid RD Directed evolution of the fatty-acid hydyoxylase P450BM-3 into an indole-hydroxylating catalyst	19	8
3376	9	12088 2000 GENE 260(1-2):13-23 Finta C; Zaphiropoulos PG The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons	25	8
3377	16	12614 2001 PHARMACOGENETICS 11(2):111-121 Gellner K; Eiselt R; Hustert E; Arnold H; Koch I; Haberl M; Deglmann CJ; Burk O; Buntefuss D; Escher S; Bishop C; Koebe HG; Brinkmann U; Klenk HP; Kleine K; Meyer UA; Wojnowski L Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene	29	8
3378	3	61 1959 JOURNAL OF BIOLOGICAL CHEMISTRY 234(3):662-665 GIUDITTA A; SINGER TP STUDIES ON SUCCINIC DEHYDROGENASE .10. REACTIVITY WITH ELECTRON CARRIERS IN RESPIRATORY CHAIN PREPARATIONS FROM HEART	32	7
3379	4	123 1961 BIOCHEMICAL JOURNAL 79(3):537-& KREBS HA; DALESSANDRI A; EGGLESTON LV EFFECT OF SUCCINATE AND AMYTAL ON REDUCTION OF ACETOACETATE IN ANIMAL TISSUES	67	7
3380	1	142 1961 NATURE 191(478):718-& HESS R; PEARSE AGE HISTOCHEMICAL AND HOMOGENIZATION STUDIES OF MITOCHONDRIAL ALPHA-GLYCEROPHOSPHATE DEHYDROGENASE IN NERVOUS SYSTEM	39	7
3381	5	157 1962 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 8(4):314-& HEDMAN R; SURANYI EM; LUFT R; ERNSTER L OXIDATION OF EXTERNAL DPNH BY MITOCHONDRIA FROM HUMAN AND RAT SKELETAL MUSCLE	22	7
3382	2	158 1962 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 8(5):361-& CAIN DF; DAVIES RE BREAKDOWN OF ADENOSINE TRIPHOSPHATE DURING A SINGLE CONTRACTION OF WORKING MUSCLE	206	7
3383	0	166 1962 BIOCHIMICA ET BIOPHYSICA ACTA 56(1):181-& ESTABROOK RW PYRIDINE NUCLEOTIDE REDUCTION ASSOICATED WITH GLUCOSE METABOLISM BY ESCHERICHIA COLI	0	7
3384	3	192 1962 NATURE 196(4851):214-& CAIN DF; INFANTE AA; DAVIES RE CHEMISTRY OF MUSCLE CONTRACTION ADENOSINE TRIPHOSPHATE AND PHOSPHORYLCREATINE AS ENERGY SUPPLIES FORR SINGLE CONTRACTIONS OF WORKING MUSCLE	144	7
3385	4	211 1963 BIOCHIMICA ET BIOPHYSICA ACTA 67(2):254-& CONOVER TE; DANIELSON L; ERNSTER L DT DIAPHORASE .3. SEPARATION OF MITOCHONDRIAL DT DIAPHORASE AND RESPIRATORY CHAIN	24	7
3386	3	213 1963 BIOCHIMICA ET BIOPHYSICA ACTA 71(3):595-& HOMMES FA A SOLUBLE FACTOR FROM MITOCHONDRIA STIMULATING RATE OF ENERGY- REQUIRING PYRIDINE NUCLEOTIDE REDUCTION	15	7
3387	5	217 1963 BIOCHIMICA ET BIOPHYSICA ACTA 77(2):173-& HOMMES FA SUCCINATE-LINKED NICOTINAMIDE-ADENINE DINUCLEOTIDE REDUCTION IN SUBMITOCHONDRIAL PARTICLES .1. KINETIC STUDIES OF REACTION	21	7
3388	2	221 1963 BIOCHIMICA ET BIOPHYSICA ACTA 77(4):592-& YAMANAKA T; OKUNUKI K; TOKUYAMA S CYTOCHROMES PURIFIED FROM LARVA, PUPA AND ADULT HOUSEFLY, MUSCA DOMESTICA L	28	7
3389	2	235 1963 JOURNAL OF BIOLOGICAL CHEMISTRY 238(1):445-& CHANCE B; HOLLUNGER G INHIBITION OF ELECTRON AND ENERGY TRANSFER IN MITOCHONDRIA .4. INHIBITION OF ENERGY-LINKED DIPHOSPHOPYRIDINE NUCLEOTIDE REDUCTION BY UNCOUPLING AGENTS	35	7
3390	4	242 1963 JOURNAL OF GENERAL PHYSIOLOGY 46(5):905-& JOBSIS FF SPECTROPHOTOMETRIC STUDIES ON INTACT MUSCLE .1. COMPONENTS OF RESPIRATORY CHAIN	49	7
3391	1	285 1964 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 17(6):648-& KAWASAKI T; KAPLAN NO; SATOH K INVOLVEMENT OF PYRIDINE NUCLEOTIDE TRANSHYDROGENASE IN ATP- LINKED TPN REDUCTION BY DPNH	49	7
3392	4	346 1964 SCIENCE 145(363):606-& SACKTOR B; DICK AR OXIDATION OF EXTRAMITOCHONDRIAL DIPHOSPHOPYRIDINE NUCLEOTIDE BY VARIOUS TISSUES OF MOUSE	22	7
3393	20	352 1965 ANNUAL REVIEW OF BIOCHEMISTRY 34():21-& SANADI DR ENERGY-LINKED REACTIONS IN MITOCHONDRIA	37	7
3394	14	408 1965 EXPERIMENTAL CELL RESEARCH 38(2):217-& MOHRI H; MOHRI T; ERNSTER L ISOLATION AND ENZYMIC PROPERTIES OF MIDPIECE OF BULL SPERMATOZOA	97	7
3395	2	525 1966 JOURNAL OF BIOCHEMISTRY 59(5):501-& OZAWA K; SETA K; TAKEDA H; ANDO K; HANDA H; ARAKI C ON ISOLATION OF MITOCHONDRIA WITH HIGH RESPIRATORY CONTROL FROM RAT BRAIN	176	7
3396	4	582 1967 ANNUAL REVIEW OF MEDICINE 18():35-& LIEBER CS METABOLIC DERANGEMENT INDUCED BY ALCOHOL	106	7
3397	6	589 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 121(2):271-& STOREY BT EFFECT OF CYANIDE AND ANTIMYCIN A ON REDUCTION OF CYTOCHROME B AND UBIQUINONE IN ELECTRON TRANSPORT PARTICLES	11	7
3398	2	614 1967 BIOCHEMICAL JOURNAL 103(1):183-& NEAL RA STUDIES ON METABOLISM OF DIETHYL 4-NITROPHENYL PHOSPHOROTHIONATE (PARATHION) IN VITRO	157	7
3399	2	716 1967 NATURE 215(5109):1487-& COCKRELL RS; HARRIS EJ; PRESSMAN BC SYNTHESIS OF ATP DRIVEN BY A POTASSIUM GRADIENT IN MITOCHONDRIA	120	7
3400	11	749 1968 ANNUAL REVIEW OF PHYSIOLOGY 30():171-& BRANSOME ED ADRENAL CORTEX	53	7

#	Cited nodes	Nodes / Authors	GCS	LCS
3401	3	752 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 123(2):368-& PRUSINER S; WILLIAMS.JR; CHANCE B; PADDLE BM PYRIDINE NUCLEOTIDE CHANGES DURING THERMOGENESIS IN BROWN FAT TISSUE IN VIVO	32	7
3402	7	758 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 125(1):157-& FRENKEL R CONTROL OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE OSCILLATIONS IN BEEF HEART EXTRACTS .2. OSCILLATIONS OF GLYCOLYTIC INTERMEDIATES AND ADENINE NUCLEOTIDES	42	7
3403	5	774 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 30(5):516-& SUZUKI M; MITROPOU.KA; MYANT NB ELECTRON TRANSPORT MECHANISM ASSOCIATED WITH 12ALPHA- HYDROXYLATION OF C27 STEROIDS	28	7
3404	3	792 1968 BIOCHEMICAL PHARMACOLOGY 17(9):1901-& DEWAIDE JH; HENDERSO.PT HEPATIC N-DEMETHYLATION OF AMINOPYRINE IN RAT AND TROUT	52	7
3405	6	793 1968 BIOCHEMISTRY 7(1):305-& NICHOLLS P; MALVIYA AN INHIBITION OF NONPHOSPHORYLATING ELECTRON TRANSFER BY ZINC . PROBLEM OF DELINEATING INTERACTION SITES	29	7
3406	3	840 1968 EUROPEAN JOURNAL OF BIOCHEMISTRY 6(1):15-& PRUSINER SB; CANNON B; LINDBERG O OXIDATIVE METABOLISM IN CELLS ISOLATED FROM BROWN ADIPOSE TISSUE .I. CATECHOLAMINE AND FATTY ACID STIMULATION OF RESPIRATION	104	7
3407	5	849 1968 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 349(4):465-& DEGKWITZ E; LUFT D; PFEIFFER U; STAUDING.H MICROSOMAL ENZYME ACTIVITY (COUMARIN HYDROXYLATION NADPH OXIDATION GLUCOSE-6-PHOSPHATASE AND ESTERASE) AND CYTOCHROME CONTENT (P-450 AND B5) IN NORMAL SCORBUTIC AND FASTING GUINEA PIGS	27	7
3408	3	867 1968 JOURNAL OF BIOCHEMISTRY 63(2):219-& IMAI K; ASANO A; SATO R OXIDATIVE PHOSPHORYLATION IN MICROCOCCUS DENITRIFICANS .V. EFFECTS OF IRON DEFICIENCY ON RESPIRATORY COMPONENTS AND OXIDATIVE PHOSPHORYLATION	19	7
3409	4	1065 1969 EUROPEAN JOURNAL OF BIOCHEMISTRY 8(2):153-& LEE CP; ERNSTER L; CHANCE B STUDIES OF ENERGY-TRANSFER SYSTEM OF SUBMITOCHONDRIAL PARTICLES - KINETIC STUDIES OF EFFECT OF OLIGOMYCIN ON RESPIRATORY CHAIN OF EDTA PARTICLES	61	7
3410	7	1101 1969 JOURNAL OF BIOCHEMISTRY 65(3):385-& ISHIDATE K; KAWAGUCH.K; TAGAWA K CHANGE IN P-450 CONTENT ACCOMPANYING AEROBIC FORMATION OF MITOCHONDRIA IN YEAST	33	7
3411	10	1161 1969 PLANT PHYSIOLOGY 44(3):413-& STOREY BT RESPIRATORY CHAIN OF PLANT MITOCHONDRIA .3. OXIDATION RATES OF CYTOCHROMES C AND B IN MUNG BEAN MITOCHONDRIA REDUCED WITH SUCCINATE	35	7
3412	3	1214 1970 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 41(5):1273-& WILSON DF; ERECINSK.M; DUTTON PL; TSUDZUKI T OXIDATION-REDUCTION POTENTIALS OF IRON-SULFUR PROTEINS IN MITOCHONDRIA	42	7
3413	4	1229 1970 BIOCHEMICAL PHARMACOLOGY 19(3):895-& BECKING GC; MORRISON AB HEPATIC DRUG METABOLISM IN ZINC-DEFICIENT RATS	52	7
3414	3	1230 1970 BIOCHEMICAL PHARMACOLOGY 19():973-& CUMMING JF; MANNERIN.GJ EFFECT OF PHENOBARBITAL ADMINISTRATION ON OXYGEN REQUIREMENT FOR HEXOBARBITAL METABOLISM IN ISOLATED, PERFUSED RAT LIVER AND IN INTACT RAT	46	7
3415	6	1241 1970 BIOCHEMICAL PHARMACOLOGY 19(7):2317-& LOMBROZO L; MITOMA C EFFECT OF CAFFEINE ON HEPATIC MICROSOMAL CYTOCHROME-P-450	28	7
3416	3	1244 1970 BIOCHEMICAL PHARMACOLOGY 19(9):2639-& BECKING GC; MORRISON AB ROLE OF DIETARY MAGNESIUM IN METABOLISM OF DRUGS BY NADPH- DEPENDENT RAT LIVER MICROSOMAL ENZYMES	22	7
3417	9	1259 1970 BIOCHIMICA ET BIOPHYSICA ACTA 208(1):116-& KATO R; TAKAHASH.A; OMORI Y EFFECTS OF THYROXINE AND THYROIDECTOMY ON HYDROXYLATION OF TESTOSTERONE BY LIVER MICROSOMES FROM MALE AND FEMALE RATS	36	7
3418	9	1288 1970 ENDOCRINOLOGIA JAPONICA 17(3):207-& KATO R; TAKAHASH.A; ONODA KI; OMORI Y EFFECT OF ADRENALECTOMY ON SUBSTRATE INTERACTION WITH CYTOCHROME P-450 IN HYDROXYLATION OF STEROID HORMONES BY LIVER MICROSOMES	13	7
3419	8	1300 1970 EUROPEAN JOURNAL OF BIOCHEMISTRY 16(3):430-& CLAISSE ML; PEREAUBE.GA; CLAVILIE.LP; SLONIMSK.PP METHOD FOR ESTIMATION OF CYTOCHROME CONCENTRATION IN WHOLE YEAST CELLS	88	7
3420	11	1410 1970 STEROIDS 15(2):251-& TSANG CPW; PERON FG FURTHER STUDIES ON CORTICOSTEROIDOGENESIS .7. FACTORS INFLUENCING UTILAZATION OF PYRUVATE FOR STEROID 11BETA- HYDROXYLATION BY RAT ADRENAL MITOCHONDRIA	18	7
3421	1	1414 1970 TOXICOLOGY AND APPLIED PHARMACOLOGY 16(3):728-& STOCK BH; HANSEN AR; FOUTS JR STIMULATION OF HEPATIC MICROSOMAL ANILINE PARA-HYDROXYLASE ACTIVITY BY DIMETHYL SULFOXIDE ADMINISTRATION TO RATS	22	7
3422	5	1421 1971 ACTA PHARMACOLOGICA ET TOXICOLOGICA 29(2-3):284-& PELKONEN O; VORNE M; JOUPPILA P; KARKI NT METABOLISM OF CHLORPROMAZINE AND PARA NITROBENZOIC ACID IN LIVER, INTESTINE AND KIDNEY OF HUMAN FOETUS	60	7
3423	4	1447 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(1):445-& CASWELL AH ESTIMATION OF REDOX POTENTIALS OF CYTOCHROMES IN MITOCHONDRIA	26	7
3424	5	1454 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 145(1):319-& GHOSH AK; CHANCE B; PYE EK METABOLIC COUPLING AND SYNCHRONIZATION OF NADH OSCILLATIONS IN YEAST CELL POPULATIONS	38	7
3425	5	1471 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 44(5):1065-& HUANG JJ; KIMURA T SPECIFIC ROLE OF REDUCED ADRENODOXIN IN ADRENAL MITOCHONDRIAL STEROID HYDROXYLASES	10	7
3426	0	1483 1971 BIOCHEMICAL JOURNAL 125(2):P3-& ESTABROOK RW; BARON J; PETERSON J; ISHIMURA Y OXYGENATED CYTOCHROME P-450 AS AN INTERMEDIATE IN HYDROXYLATION REACTIONS	7	7
3427	4	1534 1971 BIOCHIMICA ET BIOPHYSICA ACTA 245(1):175-& FEE JA; PALMER G PROPERTIES OF PARSLEY FERREDOXIN AND ITS SELENIUM-CONTAINING HOMOLOG	71	7
3428	3	1602 1971 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 19(1):58-& SELL JL; DAVISON KL; PUYEAR RL ANILINE HYDROXYLASE, N-DEMETHYLASE, AND CYTOCHROME-P450 IN LIVER MICROSOMES OF HENS FED DDT AND DIELDRIN	16	7
3429	8	1607 1971 JOURNAL OF BIOCHEMISTRY 70(4):557-& ANDO N; HORIE S STUDIES ON P-450 .8. EFFECTS OF STEROIDS ON REACTION WITH OXYGEN AND RATE OF REDUCTION OF PARTIALLY PURIFIED P-450 FROM ADRENOCORTICAL MITOCHONDRIA	14	7
3430	4	1608 1971 JOURNAL OF BIOCHEMISTRY 70(5):755-& OZAWA K; TAKASAN H; KITAMURA O; MIZUKAMI T; KAMANO T; TAKEDA H; OHSAWA T; MURATA T; HONJO I EFFECT OF LIGATION OF PORTAL VEIN ON LIVER MITOCHONDRIAL METABOLISM	102	7
3431	1	1611 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(2):402-& PANDE SV; BLANCHAE.MC REVERSIBLE INHIBITION OF MITOCHONDRIAL ADENOSINE DIPHOSPHATE PHOSPHORYLATION BY LONG CHAIN ACYL COENZYME-A ESTERS	319	7
3432	3	1612 1971 JOURNAL OF BIOLOGICAL CHEMISTRY 246(2):475-& MAITRA PK; LOBO Z KINETIC STUDY OF GLYCOLYTIC ENZYME SYNTHESIS IN YEAST	193	7
3433	5	1712 1972 ACTA ENDOCRINOLOGICA 70(2):315-& KAHNT FW; NEHER R ADRENOCORTICAL STEROID BIOSYNTHESIS IN-VITRO - PART .5. ACTIVATORS AND INHIBITORS - EVIDENCE FOR PRESENCE OF SUBSTRATE- SPECIFIC 21-HYDROXYLASES	26	7
3434	9	1737 1972 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 149(2):388-& WINFREE AT OSCILLATORY GLYCOLYSIS IN YEAST - PATTERN OF PHASE RESETTING BY OXYGEN	47	7
3435	1	1768 1972 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 47(2):315-& CASTRO JA; CASTRO CRD; DACOSTA N; FERREYRA EC; FENOS OMD; DIAZGOME.MI CARBON-TETRACHLORIDE EFFECT ON RAT-LIVER AND ADRENALS RELATED TO THEIR MIXED-FUNCTION OXYGENASE CONTENT	36	7
3436	8	1791 1972 BIOCHEMICAL PHARMACOLOGY 21(11):1585-& BECKING GC INFLUENCE OF DIETARY IRON LEVELS ON HEPATIC DRUG-METABOLISM IN- VIVO AND IN-VITRO IN RAT	45	7
3437	3	1858 1972 CHEMICO-BIOLOGICAL INTERACTIONS 5(3):201-& KUPFER D; JANSSON I; ORRENIUS S SPECTRAL INTERACTIONS OF MARIHUANA CONSTITUENTS (CANNABINOIDS) WITH RAT-LIVER MICROSOMAL MONOOXYGENASE SYSTEM	24	7
3438	8	1862 1972 CLINICA CHIMICA ACTA 38(2):385-& OZAWA K; TAKASAN H; TAKEDD H; YAMAOKA Y; KAMANO T; KITAMURA O; HONJO I; MIZUKAMI T HUMAN LIVER-MITOCHONDRIA	119	7
3439	3	1887 1972 FEBS LETTERS 22(2):165-& PFEIFFER DR; TCHEN TT; KIMURA T ROLE OF ADRENOCORTICAL MITOCHONDRIAL MALIC ENZYME IN NADPH GENERATION	10	7
3440	12	1989 1972 PATHOLOGIA EUROPAEA 7(1):43-& DENK H CHEMICAL STRUCTURE OF ENDOPLASMIC-RETICULUM AND FUNCTION OF MICROSOMAL BIOTRANSFORMATION SYSTEM OF LIVER-CELL OF RATS IN EXPERIMENTAL CHOLESTASE	15	7
3441	4	2081 1973 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 51(2):480-486 HANSFORD RG; LEHNINGE.AL ACTIVE OXIDATIVE DECARBOXYLATION OF MALATE BY MITOCHONDRIA ISOLATED FROM L-1210 ASCITES TUMOR-CELLS	25	7
3442	11	2105 1973 BIOCHEMICAL PHARMACOLOGY 22(12):1517-1520 HAYES JR; MGBODILE MU; CAMPBELL TC DEPENDENCE OF KM AN VMAX ON SUBSTRATE CONCENTRATION FOR RAT HEPATIC MICROSOMAL ETHYLMORPHINE N-DEMETHYLASE	24	7
3443	2	2172 1973 CHEMICO-BIOLOGICAL INTERACTIONS 6(4):249-257 BUNYAN PJ; PAGE JMJ PESTICIDE-INDUCED CHANGES IN HEPATIC MICROSOMAL ENZYME-SYSTEMS - SOME EFFECTS OF 1,1-DI(PARA-CHLOROPHENYL)-2,2- DICHLOROETHYLENE (DDE) AND 1,1-DI(PARA-CHLOROPHENYL)-2- CHLOROETHYLENE (DDMU) IN RAT AND JAPANESE-QUAIL	28	7
3444	12	2175 1973 CLINICAL PHARMACOLOGY & THERAPEUTICS 14(4):666-672 RANE A; SJOQVIST F; ORRENIUS S DRUGS AND FETAL METABOLISM	53	7
3445	0	2242 1973 FEDERATION PROCEEDINGS 32(MAR):761-& WERRINGLOER J; ESTABROOK RW SPECTRAL CHARACTERIZATION OF PRODUCT-CYTOCHROME P-450 COMPLEX- FORMATION	7	7
3446	6	2286 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(8):2868-2875 KAN KW; UNGAR F CHARACTERIZATION OF AN ADRENAL ACTIVATOR FOR CHOLESTEROL SIDE- CHAIN CLEAVAGE	55	7
3447	7	2325 1973 LIFE SCIENCES 13(12):1677-1691 STEVENS JT; GREENE FE RESPONSE OF MIXED-FUNCTION OXIDASE SYSTEM OF RAT HEPATIC MICROSOMES TO PARATHION AND MALATHION AND THEIR OXYGENATED ANALOGS	13	7
3448	1	2348 1973 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 70(9):2633-2636 DEBEY P; BALNY C; DOUZOU P ENZYME ASSAY IN MICROSOMES BELOW ZERO DEGREES	20	7
3449	12	2466 1974 BIOCHIMICA ET BIOPHYSICA ACTA 348(2):285-298 BELL JJ; HARDING BW ACUTE ACTION OF ADRENOCORTICOTROPIC HORMONE ON ADRENAL STEROIDOGENESIS	34	7
3450	3	2484 1974 CHEMICO-BIOLOGICAL INTERACTIONS 9(5):327-340 FOSTER AB; JARMAN M; STEVENS JD; THOMAS P; WESTWOOD JH ISOTOPE-EFFECTS IN O-DEMETHYLATIONS MEDIATED BY RAT-LIVER MICROSOMES - APPLICATION OF DIRECT INSERTION ELECTRON-IMPACT MASS-SPECTROMETRY	74	7
3451	4	2501 1974 DRUG METABOLISM AND DISPOSITION 2(4):375-379 CHHABRA RS; FOUTS JR SEX-DIFFERENCES IN METABOLISM OF XENOBIOTICS BY EXTRAHEPATIC TISSUE IN RATS	44	7
3452	6	2545 1974 JOURNAL OF BIOCHEMISTRY 75(6):1211-1219 YOSHIDA Y; KUMAOKA H; SATO R STUDIES ON MICROSOMAL ELECTRON-TRANSPORT SYSTEM OF ANAEROBICALLY GROWN YEAST .2. PURIFICATION AND CHARACTERIZATION OF CYTOCHROME B5	39	7
3453	5	2600 1974 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 285(4):355-366 SCHULTEHERMANN R; LEBERL C; LANDGRAF H; KORANSKY W LIVER GROWTH AND MIXED-FUNCTION OXIDASE ACTIVITY - DOSE- DEPENDENT STIMULATORY AND INHIBITORY EFFECTS OF ALPHA- HEXACHLOROCYCLOHEXANE	26	7
3454	6	2640 1975 ACTA BIOLOGICA ET MEDICA GERMANICA 34(11-1):1745-1754 BAESS D; JANIG GR; RUCKPAUL K INTERACTION OF COMPONENTS OF CYTOCHROME-P-450 MONOOXYGENASE SYSTEM FROM LIVER-MICROSOMES .1. IMMOBILIZATION OF SOLUBILIZED AND PARTIALLY PURIFIED PROTEIN-COMPONENTS	22	7
3455	11	2643 1975 ACTA PHARMACOLOGICA ET TOXICOLOGICA 37(3):185-200 GRUNDIN R METABOLIC INTERACTION OF ETHANOL AND ALPRENOLOL IN ISOLATED LIVER-CELLS	24	7
3456	6	2670 1975 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 166(1):313-317 ARCHAKOV AI; DEVICHENSKII VM ELECTRON-TRANSFER IN MEMBRANES OF ENDOPLASMIC-RETICULUM - QUANTITATIVE ESTIMATION OF CYTOCHROME-B5 CONTENT IN NADPH- OXIDATION AND NADH-OXIDATION CHAINS	8	7
3457	6	2686 1975 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 64(3):814-822 JERNSTROM B; CAPDEVILA J; JAKOBSSON S; ORRENIUS S SOLUBILIZATION AND PARTIAL-PURIFICATION OF CYTOCHROME-P-450 FROM RAT LUNG MICROSOMES	16	7
3458	8	2697 1975 BIOCHEMICAL PHARMACOLOGY 24(12):227-233 JUCHAU MR; ZACHARIAH PK COMPARATIVE STUDIES ON OXIDATION AND REDUCTION OF DRUG SUBSTRATES IN HUMAN PLACENTAL VERSUS RAT HEPATIC MICROSOMES	29	7
3459	7	2911 1975 TOXICOLOGY AND APPLIED PHARMACOLOGY 34(1):102-114 DIAZGOMEZ MI; CASTRO CRD; DACOSTA N; FENOS OMD; FERREYRA ECD; CASTRO JA SPECIES-DIFFERENCES IN CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY - ROLE OF CCL4 ACTIVATION AND OF LIPID PEROXIDATION	41	7
3460	6	2947 1976 ANNALS OF CLINICAL RESEARCH 8():182-192 OZOLS J ROLE OF MICROSOMAL CYTOCHROME-B5 IN METABOLISM OF ETHANOL, DRUGS AND DESATURATION OF FATTY-ACIDS	17	7
3461	10	2989 1976 BIOCHEMICAL PHARMACOLOGY 25(1):100-103 CINTI DL; LEMELIN MA; CHRISTIAN J INDUCTION OF LIVER MICROSOMAL MIXED-FUNCTION OXIDASES BY VOLATILE HYDROCARBONS	30	7
3462	7	2991 1976 BIOCHEMICAL PHARMACOLOGY 25(3):329-335 KHANNA JM; KALANT H; YEE Y; CHUNG S; SIEMENS AJ EFFECT OF CHRONIC ETHANOL TREATMENT ON METABOLISM OF DRUGS INVITRO AND INVIVO	64	7
3463	5	3067 1976 DRUG METABOLISM AND DISPOSITION 4(5):442-450 POHL RJ; PHILPOT RM; FOUTS JR CYTOCHROME-P-450 CONTENT AND MIXED-FUNCTION OXIDASE ACTIVITY IN MICROSOMES ISOLATED FROM MOUSE SKIN	70	7
3464	9	3068 1976 DRUG METABOLISM AND DISPOSITION 4(5):451-459 TREDGER JM; CHHABRA RS PRESERVATION OF VARIOUS MICROSOMAL DRUG-METABOLIZING COMPONENTS IN TISSUE PREPARATIONS FROM LIVERS, LUNGS, AND SMALL-INTESTINES OF RODENTS	27	7
3465	6	3169 1976 MOLECULAR PHARMACOLOGY 12(1):156-166 THURMAN RG; MCKENNA WR; MCCAFFREY TB PATHWAYS RESPONSIBLE FOR ADAPTIVE INCREASE IN ETHANOL UTILIZATION FOLLOWING CHRONIC TREATMENT WITH ETHANOL - INHIBITOR STUDIES WITH HEMOGLOBIN-FREE PERFUSED RAT-LIVER	88	7
3466	9	3223 1977 ACTA BIOLOGICA ET MEDICA GERMANICA 36(9):1243-1251 PFEIL D; JANIG GR; BEHLKE J; RUCKPAUL K INTERACTIONS OF COMPONENTS OF CYTOCHROME-P-450 MONO-OXYGENASE SYSTEM FROM LIVER-MICROSOMES .3. N-DEMETHYLATION ACTIVITY OF CYTOCHROME-P-450 IN DEPENDENCE ON DEGREE OF ITS INTEGRATION	7	7
3467	12	3271 1977 BIOCHEMICAL PHARMACOLOGY 26(2):109-114 POHL LR; PORTER WR; TRAGER WF; FASCO MJ; FENTON JW STEREOCHEMICAL BIOTRANSFORMATION OF WARFARIN AS A PROBE OF HOMOGENEITY AND MECHANISM OF MICROSOMAL HYDROXYLASES	42	7
3468	5	3284 1977 BIOCHEMICAL PHARMACOLOGY 26(21):1979-1984 CHUNG LWK CHARACTERISTICS OF NEONATAL ANDROGEN-INDUCED IMPRINTING OF RAT HEPATIC MICROSOMAL MONOOXYGENASES	48	7
3469	14	3321 1977 CHEMICO-BIOLOGICAL INTERACTIONS 18(2):195-204 AKHREM AA; BOKUT SB; METELITZA DI NATURE OF RATE-LIMITING STEP IN ANILINE HYDROXYLATION INVOLVING CYTOCHROME-P-450 RAT-LIVER MICROSOMES	13	7
3470	26	3329 1977 CROATICA CHEMICA ACTA 49(2):163-177 COON MJ; WHITE RE; NORDBLOM GD; BALLOU DP; GUENGERICH FP HIGHLY PURIFIED LIVER MICROSOMAL CYTOCHROME-P450 - PROPERTIES AND CATALYTIC MECHANISM	20	7
3471	9	3352 1977 EUROPEAN JOURNAL OF BIOCHEMISTRY 76(2):617-623 MANSUY D; CHOTTARD JC; CHOTTARD G NITROSOALKANES AS FE(II) LIGANDS IN HEMOGLOBIN AND MYOGLOBIN COMPLEXES FORMED FROM NITROALKANES IN REDUCING CONDITIONS	40	7
3472	6	3395 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(10):3281-3285 GAVARET JM; DEME D; NUNEZ J; SALVATORE G SEQUENTIAL REACTIVITY OF TYROSYL RESIDUES OF THYROGLOBULIN UPON IODINATION CATALYZED BY THYROID PEROXIDASE	46	7
3473	7	3419 1977 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 203(3):712-721 FOWLER BA; HOOK GER; LUCIER GW TETRACHLORODIBENZO-PARA-DIOXIN INDUCTION OF RENAL MICROSOMAL- ENZYME SYSTEMS - ULTRASTRUCTURAL EFFECTS ON PARS RECTA (S3) PROXIMAL TUBULE CELLS OF RAT-KIDNEY	38	7
3474	12	3430 1977 LIFE SCIENCES 20(7):1139-1147 REDICK JA; KAPKE GF; VANORDEN LS; BARON J IMMUNOHISTOCHEMICAL LOCALIZATION OF ADRENAL FERREDOXIN IN BOVINE ADRENAL-CORTEX	14	7
3475	18	3441 1977 MOLECULAR PHARMACOLOGY 13(6):1092-1104 IBA MM; SOYKA LF; SCHULMAN MP CHARACTERISTICS OF LIVER MICROSOMAL DRUG-METABOLIZING ENZYME- SYSTEM OF NEWBORN RATS	37	7
3476	8	3442 1977 MUTATION RESEARCH 45(3):309-324 CALLEN DF; PHILPOT RM CYTOCHROME-P-450 AND ACTIVATION OF PRO-MUTAGENS IN SACCHAROMYCES-CEREVISIAE	74	7
3477	6	3446 1977 PHARMACOLOGICAL RESEARCH COMMUNICATIONS 9(9):833-846 RAFFAELI E; FACINO RM; SALMONA M; PITRE D INVITRO BINDING AND METABOLISM OF IOPRONIC ACID BY RAT-LIVER MICROSOMES	14	7
3478	10	3531 1978 BIOCHEMICAL PHARMACOLOGY 27(19):2301-2304 ULLRICH V; HERMANN G; WEBER P NITRITE FORMATION FROM 2-NITROPROPANE BY MICROSOMAL MONO- OXYGENASES	41	7
3479	9	3532 1978 BIOCHEMICAL PHARMACOLOGY 27(19):2321-2326 YANG CS; STRICKHART FS; KICHA LP ANALYSIS OF ARYL-HYDROCARBON HYDROXYLASE ASSAY	50	7
3480	9	3533 1978 BIOCHEMICAL PHARMACOLOGY 27(19):2376-2378 YANG CS; STRICKHART FS DIFFERENCES BETWEEN HYDROPEROXIDE-DEPENDENT AND NADPH-DEPENDENT MICROSOMAL ARYL-HYDROCARBON HYDROXYLASE-ACTIVITIES	8	7
3481	5	3566 1978 CANCER RESEARCH 38(6):1751-1756 SAUER LA; DAUCHY RT MITOCHONDRICAL MALICENZYMES .2. IDENTIFICATION AND PROPERTIES OF NICOTINAMIDE ADENINE-DINUCLEOTIDE (PHOSPHATE)+-DEPENDENT MALIC ENZYME IN MOUSE ASCITES TUMOR MITOCHONDRIA	33	7
3482	13	3633 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(14):5042-5047 INGELMANSUNDBERG M; MONTELIUS J; RYDSTROM J; GUSTAFSSON JA ACTIVE FORM OF CYTOCHROME-P-45011-BETA FROM ADRENAL-CORTEX MITOCHONDRIA	16	7
3483	6	3652 1978 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 9(3):273-286 FRASER R; LANTOS CP 18-HYDROXYCORTICOSTERONE - REVIEW	115	7
3484	4	3682 1978 PLANT PHYSIOLOGY 62(4):571-576 COOLBAUGH RC; HIRANO SS; WEST CA STUDIES ON SPECIFICITY AND SITE OF ACTION OF ALPHA-CYCLOPROPYL- ALPHA-[P-METHOXYPHENYL]-5-PYRIMIDINE METHYL-ALCOHOL (ANCYMIDOL), A PLANT-GROWTH REGULATOR	114	7
3485	9	3716 1979 ACTA BIOLOGICA ET MEDICA GERMANICA 38(2-3):153-162 PETERSON JA; MOCK DM CYTOCHROME-P-450CAM AND PUTIDAREDOXIN INTERACTION DURING ELECTRON-TRANSFER	10	7
3486	13	3780 1979 BIOCHEMICAL PHARMACOLOGY 28(13):1993-2000 KAMATAKI T; SUGIURA M; YAMAZOE Y; KATO R PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 AND NADPH- CYTOCHROME-C (P-450) REDUCTASE FROM HUMAN-LIVER MICROSOMES	41	7
3487	7	3787 1979 BIOCHEMICAL PHARMACOLOGY 28(23):3385-3390 OKITA RT; JAKOBSSON SW; PROUGH RA; MASTERS BSS LAURIC ACID HYDROXYLATION IN HUMAN-LIVER AND KIDNEY CORTEX MICROSOMES	23	7
3488	6	3797 1979 BIOCHIMICA ET BIOPHYSICA ACTA 546(2):307-315 RICH PR; TIEDE DM; BONNER WD STUDIES ON THE MOLECULAR-ORGANIZATION OF CYTOCHROMES P-450 AND B5 IN THE MICROSOMAL MEMBRANE	25	7
3489	1	3809 1979 CANCER RESEARCH 39(8):3194-3198 LORENTZEN RJ; LESKO SA; MCDONALD K; TSO POP TOXICITY OF METABOLIC BENZO(A)PYRENEDIONES TO CULTURED-CELLS AND THE DEPENDENCE UPON MOLECULAR-OXYGEN	57	7
3490	15	3825 1979 DRUG METABOLISM AND DISPOSITION 7(3):166-170 DEGRAEVE J; GIELEN JE; KAHL GF; TUTTENBERG KH; KAHL R; MAUME B FORMATION OF 2 METYRAPONE N-OXIDES BY RAT-LIVER MICROSOMES	20	7
3491	3	3837 1979 EUROPEAN JOURNAL OF BIOCHEMISTRY 94(1):99-107 WOJTCZAK L; NALECZ MJ SURFACE-CHARGE OF BIOLOGICAL-MEMBRANES AS A POSSIBLE REGULATOR OF MEMBRANE-BOUND ENZYMES	167	7
3492	14	3862 1979 JAPANESE JOURNAL OF PHARMACOLOGY 29(2):191-201 KAMATAKI T; KITADA M; SHIGEMATSU H; KITAGAWA H INVOLVEMENT OF CYTOCHROME P-448 AND P-450 IN NADH-DEPENDENT O- DEMETHYLATION OF P-NITROANISOLE IN RAT-LIVER MICROSOMES	29	7
3493	10	3912 1979 LIFE SCIENCES 25(12):1085-1089 ANDERS MW; GANDER JE ACETONE ENHANCEMENT OF CUMENE HYDROPEROXIDE SUPPORTED MICROSOMAL ANILINE HYDROXYLATION	10	7
3494	54	3942 1979 PHARMACOLOGY & THERAPEUTICS 7(2):297-311 POWIS G; JANSSON I STOICHIOMETRY OF THE MIXED-FUNCTION OXIDASE	17	7
3495	4	3967 1979 TRENDS IN BIOCHEMICAL SCIENCES 4(8):171-176 DAWSON AG OXIDATION OF CYTOSOLIC NADH FORMED DURING AEROBIC METABOLISM IN MAMMALIAN-CELLS	74	7
3496	5	3971 1979 XENOBIOTICA 9(4):209-218 GORROD JW; DAMANI LA SOME FACTORS INVOLVED IN THE N-OXIDATION OF 3-SUBSTITUTED PYRIDINES BY MICROSOMAL PREPARATIONS INVITRO	23	7
3497	3	3989 1980 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH 19(11):909-910 MANSUY D; BARTOLI JF; CHOTTARD JC; LANGE M METALLOPORPHYRIN-CATALYZED HYDROXYLATION OF CYCLOHEXANE BY ALKYL HYDROPEROXIDES - PRONOUNCED EFFICIENCY OF IRON-PORPHYRINS	87	7
3498	5	3997 1980 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 201(1):104-109 TOFILON PJ; PIPER WN MEASUREMENT AND REGULATION OF RAT TESTICULAR DELTA- AMINOLEVULINIC-ACID SYNTHETASE-ACTIVITY	18	7
3499	5	4013 1980 BIOCHEMICAL JOURNAL 186(1):119-126 YUKI T; THURMAN RG SWIFT INCREASE IN ALCOHOL METABOLISM - TIME COURSE FOR THE INCREASE IN HEPATIC OXYGEN-UPTAKE AND THE INVOLVEMENT OF GLYCOLYSIS	95	7
3500	26	4029 1980 BIOCHEMICAL PHARMACOLOGY 29(8):1141-1147 KAMATAKI T; KITADA M; CHIBA K; KITAGAWA H; IMAI Y; SATO R ENHANCEMENT BY CYANIDE OF ANILINE PARA-HYDROXYLATION ACTIVITY IN RAT-LIVER MICROSOMES	17	7

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