#	Cited nodes	Nodes / Authors	GCS	LCS
601	20	2392 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 160(1):230-245 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .2. REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-P-450 AS ELECTRON CARRIERS IN MICROSOMAL NADH-PEROXIDASE ACTIVITY	93	37
602	9	2414 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 58(2):516-522 WEST SB; LEVIN W; RYAN D; VORE M; LU AYH LIVER MICROSOMAL ELECTRON-TRANSPORT SYSTEMS .2. INVOLVEMENT OF CYTOCHROME B5 IN NADH-DEPENDENT HYDROXYLATION OF 3,4-BENZPYRENE BY A RECONSTITUTED CYTOCHROME P-448-CONTAINING SYSTEM	49	37
603	10	2689 1975 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 66(1):209-216 HRYCAY EG; GUSTAFSSON JA; INGELMANSUNDBERG M; ERNSTER L SODIUM PERIODATE, SODIUM-CHLORITE, ORGANIC HYDROPEROXIDES, AND H2O2 AS HYDROXYLATING AGENTS IN STEROID HYDROXYLATION REACTIONS CATALYZED BY PARTIALLY PURIFIED CYTOCHROME-P-450	120	37
604	11	2707 1975 BIOCHEMICAL PHARMACOLOGY 24(16):1511-1515 WIEBEL FJ; GELBOIN HV ARYL-HYDROCARBON (BENZO[A]PYRENE) HYDROXYLASES IN LIVER FROM RATS OF DIFFERENT AGE, SEX AND NUTRITIONAL-STATUS - DISTINCTION OF 2 TYPES BY 7,8-BENZOFLAVONE	150	37
605	12	2732 1975 BIOCHEMISTRY 14(7):1477-1484 FOSTER RP; WILSON LD PURIFICATION AND CHARACTERIZATION OF ADRENODOXIN REDUCTASE FROM BOVINE ADRENAL-CORTEX	50	37
606	13	3138 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(23):7545-7550 LAMBETH JD; MCCASLIN DR; KAMIN H ADRENODOXIN REDUCTASE ADRENODOXIN COMPLEX - CATALYTIC AND THERMODYNAMIC PROPERTIES	65	37
607	15	4385 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(2):984-988 SAITO T; STROBEL HW PURIFICATION TO HOMOGENEITY AND CHARACTERIZATION OF A FORM OF CYTOCHROME-P-450 WITH HIGH SPECIFICITY FOR BENZO[ALPHA]PYRENE FROM BETA-NAPHTHOFLAVONE-PRETREATED RAT-LIVER MICROSOMES	100	37
608	26	5250 1984 XENOBIOTICA 14(1-2):87-104 ESTABROOK RW; MARTINWIXTROM C; SAEKI Y; RENNEBERG R; HILDEBRANDT A; WERRINGLOER J THE PEROXIDATIC FUNCTION OF LIVER MICROSOMAL CYTOCHROME-P-450 - COMPARISON OF HYDROGEN-PEROXIDE AND NADPH-CATALYZED N- DEMETHYLATION REACTIONS	37	37
609	3	6301 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(3):738-742 SZCZESNASKORUPA E; BROWNE N; MEAD D; KEMPER B POSITIVE CHARGES AT THE NH2 TERMINUS CONVERT THE MEMBRANE- ANCHOR SIGNAL PEPTIDE OF CYTOCHROME-P-450 TO A SECRETORY SIGNAL PEPTIDE	124	37
610	8	6306 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(19):7221-7225 KALB VF; LOPER JC PROTEINS FROM EIGHT EUKARYOTIC CYTOCHROME-P-450 FAMILIES SHARE A SEGMENTED REGION OF SEQUENCE SIMILARITY	65	37
611	13	6663 1989 JOURNAL OF CLINICAL INVESTIGATION 84(6):1805-1812 HIRT DL; CAPDEVILA J; FALCK JR; BREYER MD; JACOBSON HR CYTOCHROME P450 METABOLITES OF ARACHIDONIC-ACID ARE POTENT INHIBITORS OF VASOPRESSIN ACTION ON RABBIT CORTICAL COLLECTING DUCT	70	37
612	12	6867 1990 BIOCHEMICAL JOURNAL 271(1):113-119 WAXMAN DJ; MORRISSEY JJ; NAIK S; JAUREGUI HO PHENOBARBITAL INDUCTION OF CYTOCHROMES-P-450 - HIGH-LEVEL LONG- TERM RESPONSIVENESS OF PRIMARY RAT HEPATOCYTE CULTURES TO DRUG INDUCTION, AND GLUCOCORTICOID DEPENDENCE OF THE PHENOBARBITAL RESPONSE	151	37
613	7	6876 1990 BIOCHEMICAL PHARMACOLOGY 39(3):499-506 SESARDIC D; COLE KJ; EDWARDS RJ; DAVIES DS; THOMAS PE; LEVIN W; BOOBIS AR THE INDUCIBILITY AND CATALYTIC ACTIVITY OF CYTOCHROME-P450C (P450IA1) AND CYTOCHROME-P450D (P450IA2) IN RAT-TISSUES	77	37
614	12	6996 1990 CIRCULATION RESEARCH 66(3):608-621 ROSOLOWSKY M; FALCK JR; WILLERSON JT; CAMPBELL WB SYNTHESIS OF LIPOXYGENASE AND EPOXYGENASE PRODUCTS OF ARACHIDONIC-ACID BY NORMAL AND STENOSED CANINE CORONARY- ARTERIES	103	37
615	7	7028 1990 DRUG METABOLISM AND DISPOSITION 18(5):711-719 PICHARD L; GILLET G; FABRE I; DALETBELUCHE I; BONFILS C; THENOT JP; MAUREL P IDENTIFICATION OF THE RABBIT AND HUMAN CYTOCHROMES-P-450IIIA AS THE MAJOR ENZYMES INVOLVED IN THE N-DEMETHYLATION OF DILTIAZEM	113	37
616	6	7234 1990 MOLECULAR PHARMACOLOGY 37(4):489-496 DING XX; COON MJ IMMUNOCHEMICAL CHARACTERIZATION OF MULTIPLE FORMS OF CYTOCHROME-P-450 IN RABBIT NASAL MICROSOMES AND EVIDENCE FOR TISSUE-SPECIFIC EXPRESSION OF P-450S NMA AND NMB	73	37
617	6	7280 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(21):8306-8310 FORRESTER LM; NEAL GE; JUDAH DJ; GLANCEY MJ; WOLF CR EVIDENCE FOR INVOLVEMENT OF MULTIPLE FORMS OF CYTOCHROME-P-450 IN AFLATOXIN-B1 METABOLISM IN HUMAN LIVER	116	37
618	15	7617 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(6):3372-3375 SHIMIZU T; TATEISHI T; HATANO M; FUJIIKURIYAMA Y PROBING THE ROLE OF LYSINES AND ARGININES IN THE CATALYTIC FUNCTION OF CYTOCHROME-P450D BY SITE-DIRECTED MUTAGENESIS - INTERACTION WITH NADPH-CYTOCHROME-P450 REDUCTASE	69	37
619	6	7628 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(17):11276-11281 MAHENDROO MS; MEANS GD; MENDELSON CR; SIMPSON ER TISSUE-SPECIFIC EXPRESSION OF HUMAN P-450AROM - THE PROMOTER RESPONSIBLE FOR EXPRESSION IN ADIPOSE-TISSUE IS DIFFERENT FROM THAT UTILIZED IN PLACENTA	121	37
620	15	7847 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 292(1):20-28 BODDUPALLI SS; PRAMANIK BC; SLAUGHTER CA; ESTABROOK RW; PETERSON JA FATTY-ACID MONOOXYGENATION BY P450BM-3 - PRODUCT IDENTIFICATION AND PROPOSED MECHANISMS FOR THE SEQUENTIAL HYDROXYLATION REACTIONS	37	37
621	24	8037 1992 CRITICAL REVIEWS IN TOXICOLOGY 21(6):407-422 KAMINSKY LS; FASCO MJ SMALL INTESTINAL CYTOCHROMES-P450	111	37
622	8	8311 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(6):2145-2149 BURGER HJ; SCHUETZ JD; SCHUETZ EG; GUZELIAN PS PARADOXICAL TRANSCRIPTIONAL ACTIVATION OF RAT-LIVER CYTOCHROME- P-450 3A1 BY DEXAMETHASONE AND THE ANTIGLUCOCORTICOID PREGNENOLONE 16-ALPHA-CARBONITRILE - ANALYSIS BY TRANSIENT TRANSFECTION INTO PRIMARY MONOLAYER-CULTURES OF ADULT-RAT HEPATOCYTES	80	37
623	66	8349 1992 XENOBIOTICA 22(1):83-103 SOUCEK P; GUT I CYTOCHROMES P-450 IN RATS - STRUCTURES, FUNCTIONS, PROPERTIES AND RELEVANT HUMAN FORMS	154	37
624	23	9099 1994 ENDOCRINE REVIEWS 15(3):342-355 SIMPSON ER; MAHENDROO MS; MEANS GD; KILGORE MW; HINSHELWOOD MM; GRAHAMLORENCE S; AMARNEH B; ITO YJ; FISHER CR; MICHAEL MD; MENDELSON CR; BULUN SE AROMATASE CYTOCHROME-P450, THE ENZYME RESPONSIBLE FOR ESTROGEN BIOSYNTHESIS	343	37
625	36	9339 1994 PHYTOCHEMISTRY 37(6):1491-1506 BOLWELL GP; BOZAK K; ZIMMERLIN A PLANT CYTOCHROME-P450	116	37
626	70	10629 1997 CLINICAL PHARMACOKINETICS 32(3):210-258 Bertz RJ; Granneman GR Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions	274	37
627	12	10745 1997 JOURNAL OF BIOLOGICAL CHEMISTRY 272(2):1127-1135 GrahamLorence S; Truan G; Peterson JA; Falck JR; Wei SZ; Helvig C; Capdevila JH An active site substitution, F87V, converts cytochrome p450 BM- 3 into a regio- and stereoselective (14S,15R)-arachidonic acid epoxygenase	54	37
628	29	11255 1998 JOURNAL OF BIOLOGICAL CHEMISTRY 273(6):3158-3165 Auchus RJ; Lee TC; Miller WL Cytochrome b(5) augments the 17,20-lyase activity of human P450c17 without direct electron transfer	89	37
629	3	25 1958 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 76(2):532-545 ESTABROOK RW; SACKTOR B THE RESPIRATORY METABOLISM OF INSECT FLIGHT MUSCLE .3. LOW- TEMPERATURE SPECTRA OF THE CYTOCHROMES OF FLIGHT MUSCLE SARCOSOMES	36	36
630	1	42 1958 NATURE 182(4644):1190-1193 CHANCE B; HOLMES W; HIGGINS J; CONNELLY CM LOCALIZATION OF INTERACTION SITES IN MULTI-COMPONENT TRANSFER SYSTEMS - THEOREMS DERIVED FROM ANALOGUES	165	36
631	1	605 1967 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 28(3):426-& CASTRO JA; GILLETTE JR SPECIES AND SEX DIFFERENCES IN KINETIC CONSTANTS FOR N- DEMETHYLATION OF ETHYL-MORPHINE BY LIVER MICROSOMES	78	36
632	2	719 1967 NAUNYN-SCHMIEDEBERGS ARCHIV FUR PHARMAKOLOGIE 259(1):1-& NETTER KJ; JENNER S; KAJUSCHK.K EFFECT OF METYRAPONE ON MICROSOMAL DRUG METABOLISM	62	36
633	7	904 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(23):6250-& NEBERT DW; GELBOIN HV SUBSTRATE-INDUCIBLE MICROSOMAL ARYL HYDROXYLASE IN MAMMALIAN CELL CULTURE .2. CELLULAR RESPONSES DURING ENZYME INDUCTION	229	36
634	13	2038 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):27-49 ESTABROOK RW; MASON JI; BARON J; LAMBETH D; WATERMAN M DRUGS, ALCOHOL AND SEX-HORMONES - MOLECULAR PERSPECTIVE OF RECEPTIVITY OF CYTOCHROME-P-450	36	36
635	15	4395 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(13):6829-6836 HUANG MT; CHANG RL; FORTNER JG; CONNEY AH STUDIES ON THE MECHANISM OF ACTIVATION OF MICROSOMAL BENZO[A]PYRENE HYDROXYLATION BY FLAVONOIDS	88	36
636	15	5180 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(13):8174-8182 MULLERENOCH D; CHURCHILL P; FLEISCHER S; GUENGERICH FP INTERACTION OF LIVER MICROSOMAL CYTOCHROME-P-450 AND NADPH- CYTOCHROME-P-450 REDUCTASE IN THE PRESENCE AND ABSENCE OF LIPID	74	36
637	6	5753 1987 AMERICAN JOURNAL OF PHYSIOLOGY 253(3):F464-F470 SCHLONDORFF D; PETTY E; OATES JA; JACOBY M; LEVINE SD EPOXYGENASE METABOLITES OF ARACHIDONIC-ACID INHIBIT VASOPRESSIN RESPONSE IN TOAD BLADDER	61	36
638	12	6576 1989 ENDOCRINOLOGY 124(6):2954-2966 WAXMAN DJ; MORRISSEY JJ; LEBLANC GA FEMALE-PREDOMINANT RAT HEPATIC P-450 FORMS J-(IIE1) AND 3- (IIA1) ARE UNDER HORMONAL REGULATORY CONTROLS DISTINCT FROM THOSE OF THE SEX-SPECIFIC P-450 FORMS	87	36
639	8	6714 1989 MOLECULAR PHARMACOLOGY 36(1):66-71 QUATTROCHI LC; TUKEY RH THE HUMAN CYTOCHROME CYP1A2 GENE CONTAINS REGULATORY ELEMENTS RESPONSIVE TO 3-METHYLCHOLANTHRENE	76	36
640	16	6915 1990 BIOCHEMISTRY 29(32):7381-7386 STAYTON PS; SLIGAR SG THE CYTOCHROME-P-450CAM BINDING SURFACE AS DEFINED BY SITE- DIRECTED MUTAGENESIS AND ELECTROSTATIC MODELING	102	36
641	19	7707 1991 METHODS IN ENZYMOLOGY 206():249-267 WAXMAN DJ RAT HEPATIC P450IIA AND P450IIC SUBFAMILY EXPRESSION USING CATALYTIC, IMMUNOCHEMICAL, AND MOLECULAR PROBES	80	36
642	9	7772 1991 PROTEIN ENGINEERING 4(3):271-282 ZVELEBIL MJJM; WOLF CR; STERNBERG MJE A PREDICTED 3-DIMENSIONAL STRUCTURE OF HUMAN CYTOCHROME-P450 - IMPLICATIONS FOR SUBSTRATE-SPECIFICITY	68	36
643	11	7905 1992 BIOCHEMICAL JOURNAL 288():503-509 MILES JS; MUNRO AW; ROSPENDOWSKI BN; SMITH WE; MCKNIGHT J; THOMSON AJ DOMAINS OF THE CATALYTICALLY SELF-SUFFICIENT CYTOCHROME-P-450 BM-3 - GENETIC CONSTRUCTION, OVEREXPRESSION, PURIFICATION AND SPECTROSCOPIC CHARACTERIZATION	62	36
644	29	8081 1992 EUROPEAN JOURNAL OF BIOCHEMISTRY 207(1):109-116 PEYRONNEAU MA; RENAUD JP; TRUAN G; URBAN P; POMPON D; MANSUY D OPTIMIZATION OF YEAST-EXPRESSED HUMAN LIVER CYTOCHROME-P450 3A4 CATALYTIC ACTIVITIES BY COEXPRESSING NADPH-CYTOCHROME-P450 REDUCTASE AND CYTOCHROME-B5	66	36
645	14	8415 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 307(1):57-65 ROMAN LJ; PALMER CNA; CLARK JE; MUERHOFF AS; GRIFFIN KJ; JOHNSON EF; MASTERS BSS EXPRESSION OF RABBIT CYTOCHROMES-P4504A WHICH CATALYZE THE OMEGA-HYDROXYLATION OF ARACHIDONIC-ACID, FATTY-ACIDS, AND PROSTAGLANDINS	58	36
646	19	8648 1993 HEPATOLOGY 18(5):1254-1262 SCHUETZ EG; SCHUETZ JD; STROM SC; THOMPSON MT; FISHER RA; MOLOWA DT; LI D; GUZELIAN PS REGULATION OF HUMAN LIVER CYTOCHROMES P-450 IN FAMILY 3A IN PRIMARY AND CONTINUOUS-CULTURE OF HUMAN HEPATOCYTES	111	36
647	10	8829 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(9):4102-4106 TEUTSCH HG; HASENFRATZ MP; LESOT A; STOLTZ C; GARNIER JM; JELTSCH JM; DURST F; WERCKREICHHART D ISOLATION AND SEQUENCE OF A CDNA-ENCODING THE JERUSALEM- ARTICHOKE CINNAMATE 4-HYDROXYLASE, A MAJOR PLANT CYTOCHROME- P450 INVOLVED IN THE GENERAL PHENYLPROPANOID PATHWAY	91	36
648	7	9860 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(17):7705-7709 FAULKNER KM; SHET MS; FISHER CW; ESTABROOK RW ELECTROCATALYTICALLY DRIVEN OMEGA-HYDROXYLATION OF FATTY-ACIDS USING CYTOCHROME-P450 4A1	36	36
649	33	10560 1997 BIOCHEMISTRY 36(2):370-381 Ueng YF; Kuwabara T; Chun YJ; Guengerich FP Cooperativity in oxidations catalyzed by cytochrome P450 3A4	105	36
650	7	534 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(8):1672-& TYLER DD; ESTABROOK RW INFLUENCE OF DEUTERIUM OXIDE AND ORGANIC SOLVENTS ON INTERACTION OF RESPIRATORY CHAIN COMPONENTS	34	35
651	14	2063 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 156(2):404-413 STERN JO; PEISACH J; BLUMBERG WE; LU AYH; LEVIN W LOW-TEMPERATURE EPR STUDY OF PARTIALLY PURIFIED, SOLUBLE FERRIC CYTOCHROMES P-450 AND P-448 FROM RAT-LIVER MICROSOMES	52	35
652	12	3129 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(13):3933-3941 PEDERSEN JI; GHAZARIAN JG; ORMEJOHNSON NR; DELUCA HF ISOLATION OF CHICK RENAL MITOCHONDRIAL FERREDOXIN ACTIVE IN 25- HYDROXYVITAMIN D3-1ALPHA-HYDROXYLASE SYSTEM	116	35
653	12	3489 1978 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 190(1):307-314 SATO H; ASHIDA N; SUHARA K; ITAGAKI E; TAKEMORI S; KATAGIRI M PROPERTIES OF AN ADRENAL CYTOCHROME-P-450 (P-45011-BETA) FOR HYDROXYLATIONS OF CORTICOSTEROIDS .3.	130	35
654	4	3503 1978 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 83(4):1291-1298 CAPDEVILA J; ESTABROOK RW; PROUGH RA EXISTENCE OF A BENZO(A)PYRENE-3,6-QUINONE REDUCTASE IN RAT- LIVER MICROSOMAL FRACTIONS	35	35
655	14	4448 1981 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 78(2):1028-1032 DUBOIS RN; SIMPSON ER; TUCKEY J; LAMBETH JD; WATERMAN MR EVIDENCE FOR A HIGHER MOLECULAR-WEIGHT PRECURSOR OF CHOLESTEROL SIDE-CHAIN-CLEAVAGE CYTOCHROME-P-450 AND INDUCTION OF MITOCHONDRIAL AND CYTOSOLIC PROTEINS BY CORTICOTROPIN IN ADULT BOVINE ADRENAL-CELLS	83	35
656	13	5878 1987 DRUG METABOLISM AND DISPOSITION 15(3):335-343 RITTER JK; FRANKLIN MR INDUCTION AND INHIBITION OF RAT HEPATIC DRUG-METABOLISM BY N- SUBSTITUTED IMIDAZOLE DRUGS	79	35
657	5	6367 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 268(2):525-535 KLOEPPERSAMS PJ; STEGEMAN JJ THE TEMPORAL RELATIONSHIPS BETWEEN P450E-PROTEIN CONTENT, CATALYTIC ACTIVITY, AND MESSENGER-RNA LEVELS IN THE TELEOST FUNDULUS-HETEROCLITUS FOLLOWING TREATMENT WITH BETA- NAPHTHOFLAVONE	77	35
658	5	6708 1989 MOLECULAR PHARMACOLOGY 35(4):443-449 YASUMORI T; MURAYAMA N; YAMAZOE Y; ABE A; NOGI Y; FUKASAWA T; KATO R EXPRESSION OF A HUMAN P-450IIC GENE IN YEAST-CELLS USING GALACTOSE-INDUCIBLE EXPRESSION SYSTEM	58	35
659	7	6811 1990 AMERICAN JOURNAL OF PHYSIOLOGY 259(4):H1171-H1177 ELLIS EF; POLICE RJ; YANCEY L; MCKINNEY JS; AMRUTHESH SC DILATION OF CEREBRAL ARTERIOLES BY CYTOCHROME-P-450 METABOLITES OF ARACHIDONIC-ACID	92	35
660	9	7127 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(6):3313-3319 AHLGREN R; SIMPSON ER; WATERMAN MR; LUND J CHARACTERIZATION OF THE PROMOTER REGULATORY REGION OF THE BOVINE CYP11A (P-450SCC) GENE - BASAL AND CAMP-DEPENDENT EXPRESSION	108	35
661	6	7274 1990 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 87(8):3225-3229 ELIASSON E; JOHANSSON I; INGELMANSUNDBERG M SUBSTRATE-REGULATED, HORMONE-REGULATED, AND CAMP-REGULATED CYTOCHROME P450 DEGRADATION	105	35
662	37	7292 1990 SEMINARS IN LIVER DISEASE 10(4):235-250 WATKINS PB ROLE OF CYTOCHROMES P450 IN DRUG-METABOLISM AND HEPATOTOXICITY	129	35
663	12	7644 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(33):22718-22725 OSTER T; BODDUPALLI SS; PETERSON JA EXPRESSION, PURIFICATION, AND PROPERTIES OF THE FLAVOPROTEIN DOMAIN OF CYTOCHROME-P-450BM-3 - EVIDENCE FOR THE IMPORTANCE OF THE AMINO-TERMINAL REGION FOR FMN BINDING	40	35
664	9	7980 1992 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 34(3):256-261 SKJELBO E; BROSEN K INHIBITORS OF IMIPRAMINE METABOLISM BY HUMAN LIVER-MICROSOMES	160	35
665	4	8180 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(27):19051-19053 MUERHOFF AS; GRIFFIN KJ; JOHNSON EF THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR MEDIATES THE INDUCTION OF CYP4A6, A CYTOCHROME-P450 FATTY-ACID OMEGA- HYDROXYLASE, BY CLOFIBRIC ACID	231	35
666	26	8249 1992 LIFE SCIENCES 50(20):1471-1478 GUENGERICH FP HUMAN CYTOCHROME-P-450 ENZYMES	93	35
667	6	8668 1993 JOURNAL OF BIOCHEMISTRY 113(1):7-12 FUKUDA T; IMAI Y; KOMORI M; NAKAMURA M; KUSUNOSE E; SATOUCHI K; KUSUNOSE M REPLACEMENT OF THR-303 OF P450 2E1 WITH SERINE MODIFIES THE REGIOSELECTIVITY OF ITS FATTY-ACID HYDROXYLASE-ACTIVITY	50	35
668	28	8796 1993 PHARMACOGENETICS 3(1):1-18 KORZEKWA KR; JONES JP PREDICTING THE CYTOCHROME-P450 MEDIATED METABOLISM OF XENOBIOTICS	79	35
669	20	8967 1994 BIOCHEMICAL PHARMACOLOGY 47(9):1643-1653 GORSKI JC; HALL SD; VANDENBRANDEN M; WRIGHTON SA; JONES DR REGIOSELECTIVE BIOTRANSFORMATION OF MIDAZOLAM BY MEMBERS OF THE HUMAN CYTOCHROME-P450-3A (CYP3A) SUBFAMILY	148	35
670	35	9739 1995 JOURNAL OF CLINICAL INVESTIGATION 95(5):2150-2160 ZELDIN DC; PLITMAN JD; KOBAYASHI J; MILLER RF; SNAPPER JR; FALCK JR; SZAREK JL; PHILPOT RM; CAPDEVILA JH THE RABBIT PULMONARY CYTOCHROME-P450 ARACHIDONIC-ACID METABOLIC PATHWAY - CHARACTERIZATION AND SIGNIFICANCE	54	35
671	47	10122 1996 CRITICAL REVIEWS IN PLANT SCIENCES 15(3):235-284 Schuler MA Plant cytochrome P450 monooxygenases	114	35
672	21	10198 1996 FASEB JOURNAL 10(13):1456-1463 Makita K; Falck JR; Capdevila JH Cytochrome P450, the arachidonic acid cascade, and hypertension: New vistas for an old enzyme system	80	35
673	84	10618 1997 CHEMICO-BIOLOGICAL INTERACTIONS 106(3):161-182 Guengerich FP Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species	85	35
674	10	145 1961 SCIENCE 134(348):1495-& BOXER GE; DEVLIN TM PATHWAYS OF INTRACELLULAR HYDROGEN TRANSPORT - ABSENCE OF ENZYMATIC HYDROGEN-CARRYING SYSTEMS IS A FACTOR IN AEROBIC GLYCOLYSIS OF MALIGNANT TISSUE	304	34
675	9	354 1965 ANNUAL REVIEW OF BIOCHEMISTRY 34():595-& MASON HS OXIDASES	192	34
676	4	540 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(20):4567-& CHANCE B; SCHOENER B HIGH AND LOW ENERGY STATES OF CYTOCHROMES .I. IN MITOCHONDRIA	90	34
677	6	892 1968 JOURNAL OF BIOLOGICAL CHEMISTRY 243(10):2799-& BRYSON MJ; SWEAT ML CLEAVAGE OF CHOLESTEROL SIDE CHAIN ASSOCIATED WITH CYTOCHROME P-450 FLAVOPROTEIN AND NONHEME IRON-PROTEIN DERIVED FROM BOVINE ADRENAL CORTEX	42	34
678	5	1097 1969 JOURNAL OF BIOCHEMISTRY 65(2):215-& YAGO N; ICHII S SUBMITOCHONDRIAL DISTRIBUTION OF COMPONENTS OF STEROID 11BETA- HYDROXYLASE AND CHOLESTEROL SIDECHAIN-CLEAVING ENZYME SYSTEMS IN HOG ADRENAL CORTEX	142	34
679	6	1379 1970 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 9(7):361-& ARIYOSHI T; TAKABATA.E; REMMER H DRUG METABOLISM IN ETHANOL INDUCED FATTY LIVER	106	34
680	9	1383 1970 LIFE SCIENCES PT-2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY 9(20):1189-& YAFFE SJ PRESENCE OF A MONOOXYGENASE SYSTEM IN HUMAN FETAL LIVER MICROSOMES	160	34
681	34	1724 1972 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 11(8):701-& ULLRICH V ENZYMATIC HYDROXYLATIONS WITH MOLECULAR-OXYGEN	144	34
682	4	1806 1972 BIOCHEMICAL PHARMACOLOGY 21(24):3287-& FRANKLIN MR INHIBITION OF HEPATIC OXIDATIVE XENOBIOTIC METABOLISM BY PIPERONYL BUTOXIDE	77	34
683	18	2405 1974 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 165(1):331-339 HRYCAY EG; PROUGH RA REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE-CYTOCHROME-B5 REDUCTASE AND CYTOCHROME-B5 AS ELECTRON CARRIERS IN NADH- SUPPORTED CYTOCHROME P-450-DEPENDENT ENZYME-ACTIVITIES IN LIVER-MICROSOMES	53	34
684	8	3118 1976 JOURNAL OF BIOCHEMISTRY 80(2):267-276 IMAI Y USE OF 8-AMINOOCTYL SEPHAROSE FOR SEPARATION OF SOME COMPONENTS OF HEPATIC MICROSOMAL ELECTRON-TRANSFER SYSTEM	106	34
685	29	3166 1976 LIFE SCIENCES 19(5):611-623 SCHENKMAN JB; JANSSON I; ROBIESUH KM MANY ROLES OF CYTOCHROME-B5 IN HEPATIC MICROSOMES	73	34
686	11	3400 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(14):5061-5066 RICHTER C; AZZI A; WESER U; WENDEL A HEPATIC MICROSOMAL DEALKYLATIONS - INHIBITION BY A TYROSINE.COPPER(II) COMPLEX PROVIDED WITH SUPEROXIDE-DISMUTASE ACTIVITY	73	34
687	4	3476 1978 ANALYTICAL BIOCHEMISTRY 86(2):725-732 JOHANNESEN KAM; DEPIERRE JW MEASUREMENT OF CYTOCHROME-P-450 IN PRESENCE OF LARGE AMOUNTS OF CONTAMINATING HEMOGLOBIN AND METHEMOGLOBIN	181	34
688	18	4008 1980 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 96(4):1562-1568 KUWAHARA SI; OMURA T DIFFERENT REQUIREMENT FOR CYTOCHROME-B5 IN NADPH-SUPPORTED O- DEETHYLATION OF PARA-NITROPHENETOLE CATALYZED BY 2 TYPES OF MICROSOMAL CYTOCHROME-P-450	51	34
689	26	4686 1982 MOLECULAR AND CELLULAR BIOCHEMISTRY 45(1):13-31 LAMBETH JD; SEYBERT DW; LANCASTER JR; SALERNO JC; KAMIN H STEROIDOGENIC ELECTRON-TRANSPORT IN ADRENAL-CORTEX MITOCHONDRIA	140	34
690	8	5828 1987 BIOCHIMICA ET BIOPHYSICA ACTA 919(2):132-139 TOTO R; SIDDHANTA A; MANNA S; PRAMANIK B; FALCK JR; CAPDEVILA J ARACHIDONIC-ACID EPOXYGENASE - DETECTION OF EPOXYEICOSATRIENOIC ACIDS IN HUMAN-URINE	56	34
691	10	6433 1989 BIOCHEMICAL PHARMACOLOGY 38(8):1313-1319 EKSTROM G; INGELMANSUNDBERG M RAT-LIVER MICROSOMAL NADPH-SUPPORTED OXIDASE ACTIVITY AND LIPID-PEROXIDATION DEPENDENT ON ETHANOL-INDUCIBLE CYTOCHROME-P- 450 (P-450IIE1)	246	34
692	7	6707 1989 MOLECULAR PHARMACOLOGY 35(3):279-285 HOSTETLER KA; WRIGHTON SA; MOLOWA DT; THOMAS PE; LEVIN W; GUZELIAN PS COINDUCTION OF MULTIPLE HEPATIC CYTOCHROME-P-450 PROTEINS AND THEIR MESSENGER-RNAS IN RATS TREATED WITH IMIDAZOLE ANTIMYCOTIC AGENTS	77	34
693	7	7126 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(6):3304-3312 LUND J; AHLGREN R; WU DH; KAGIMOTO M; SIMPSON ER; WATERMAN MR TRANSCRIPTIONAL REGULATION OF THE BOVINE CYP17 (P-45017-ALPHA) GENE - IDENTIFICATION OF 2 CAMP REGULATORY REGIONS LACKING THE CONSENSUS CAMP-RESPONSIVE ELEMENT (CRE)	128	34
694	23	7542 1991 ENDOCRINE REVIEWS 12(1):91-108 YANASE T; SIMPSON ER; WATERMAN MR 17-ALPHA-HYDROXYLASE 17,20-LYASE DEFICIENCY - FROM CLINICAL INVESTIGATION TO MOLECULAR DEFINITION	128	34
695	7	7724 1991 MOLECULAR ENDOCRINOLOGY 5(12):2005-2013 MEANS GD; KILGORE MW; MAHENDROO MS; MENDELSON CR; SIMPSON ER TISSUE-SPECIFIC PROMOTERS REGULATE AROMATASE CYTOCHROME-P450 GENE-EXPRESSION IN HUMAN OVARY AND FETAL TISSUES	147	34
696	20	8281 1992 MOLECULAR PHARMACOLOGY 42(6):958-963 LAETHEM RM; KOOP DR IDENTIFICATION OF RABBIT CYTOCHROMES P450 2C1 AND 2C2 AS ARACHIDONIC-ACID EPOXYGENASES	47	34
697	9	8400 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 301(2):345-354 COOPER KO; REIK LM; JAYYOSI Z; BANDIERA S; KELLEY M; RYAN DE; DANIEL R; MCCLUSKEY SA; LEVIN W; THOMAS PE REGULATION OF 2 MEMBERS OF THE STEROID-INDUCIBLE CYTOCHROME P450 SUBFAMILY (3A) IN RATS	89	34
698	26	8680 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(9):6402-6407 ZELDIN DC; KOBAYASHI J; FALCK JR; WINDER BS; HAMMOCK BD; SNAPPER JR; CAPDEVILA JH REGIOFACIAL AND ENANTIOFACIAL SELECTIVITY OF EPOXYEICOSATRIENOIC ACID HYDRATION BY CYTOSOLIC EPOXIDE HYDROLASE	55	34
699	4	8682 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(11):8350-8355 NAKAHARA K; TANIMOTO T; HATANO K; USUDA K; SHOUN H CYTOCHROME-P-450-55A1 (P-450DNIR) ACTS AS NITRIC-OXIDE REDUCTASE EMPLOYING NADH AS THE DIRECT ELECTRON-DONOR	107	34
700	3	8826 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2890-2894 SHET MS; SATHASIVAN K; ARLOTTO MA; MEHDY MC; ESTABROOK RW PURIFICATION, CHARACTERIZATION, AND CDNA CLONING OF AN NADPH- CYTOCHROME-P450 REDUCTASE FROM MUNG BEAN	34	34

#	Cited nodes	Nodes / Authors	GCS	LCS
701	19	8988 1994 BIOCHEMISTRY 33(14):4419-4424 HE YA; LUO ZS; KLEKOTKA PA; BURNETT VL; HALPERT JR STRUCTURAL DETERMINANTS OF CYTOCHROME-P450-2B1 SPECIFICITY - EVIDENCE FOR 5 SUBSTRATE RECOGNITION SITES	58	34
702	14	9431 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 317(2):343-347 KATAGIRI M; KAGAWA N; WATERMAN MR THE ROLE OF CYTOCHROME B(5) IN THE BIOSYNTHESIS OF ANDROGENS BY HUMAN P450C17	66	34
703	4	133 1961 JOURNAL OF BIOLOGICAL CHEMISTRY 236(6):1680-& YONETANI T STUDIES ON CYTOCHROME OXIDASE .3. IMPROVED PREPARATION AND SOME PROPERTIES	517	33
704	0	596 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 122(1):204-& POE M; GUTFREUN.H; ESTABROOK RW KINETIC STUDIES OF TEMPERATURE CHANGES AND OXYGEN UPTAKE IN A DIFFERENTIAL CALORIMETER - HEAT OF OXIDATION OF NADH AND SUCCINATE	33	33
705	8	727 1967 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 57(5):1498-& CHANCE B; ERNSTER L; GARLAND PB; LEE CP; LIGHT PA; OHNISHI T; RAGAN CI; WONG D FLAVOPROTEINS OF MITOCHONDRIAL RESPIRATORY CHAIN	85	33
706	5	776 1968 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 31(1):113-& SIMPSON ER; CAMMER W; ESTABROOK RW ROLE OF MALIC ENZYME IN BOVINE ADRENAL CORTEX MITOCHONDRIA	33	33
707	6	789 1968 BIOCHEMICAL PHARMACOLOGY 17(9):1759-& SASAME HA; CASTRO JA; GILLETTE JR STUDIES ON DESTRUCTION OF LIVER MICROSOMAL CYTOCHROME P-450 BY CARBON TETRACHLORIDE ADMINISTRATION	154	33
708	5	1478 1971 BIOCHEMICAL JOURNAL 123(4):539-& ELING TE; DIAUGUST.RP ROLE FOR PHOSPHOLIPIDS IN BINDING AND METABOLISM OF DRUGS BY HEPATIC MICROSOMES - USE OF FLUORESCENT HYDROPHOBIC PROBE 1- ANILINONAPHTHALENE-8-SULPHONATE	84	33
709	7	1578 1971 EUROPEAN JOURNAL OF BIOCHEMISTRY 20(4):509-& ULLRICH V; DIEHL H UNCOUPLING OF MONOOXYGENATION AND ELECTRON TRANSPORT BY FLUOROCARBONS IN LIVER MICROSOMES	96	33
710	19	2046 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):243-261 JEFCOATE CR; SIMPSON ER; BOYD GS; BROWNIE AC; ORMEJOHN.WH DETECTION OF DIFFERENT STATES OF P-450 CYTOCHROMES IN ADRENAL MITOCHONDRIA - CHANGES INDUCED BY ACTH	74	33
711	13	2050 1973 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 212(JUN22):344-360 BROWNIE AC; ALFANO J; JEFCOATE CR; ORMEJOHN.W; BEINERT H; SIMPSON ER EFFECT OF ACTH ON ADRENAL MITOCHONDRIAL CYTOCHROME-P-450 IN RAT	98	33
712	15	2249 1973 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 354(5):514-520 ULLRICH V; FROMMER U; WEBER P CHARACTERIZATION OF CYTOCHROME-P-450 SPECIES IN RAT-LIVER MICROSOMES .1. DIFFERENCES IN O-DEALKYLATION OF 7- ETHOXYCOUMARIN AFTER PRETREATMENT WITH PHENOBARBITAL AND 3- METHYLCHOLANTHRENE	119	33
713	15	2333 1973 MOLECULAR PHARMACOLOGY 9(6):840-845 JANSSON I; SCHENKMAN JB EVIDENCE AGAINST PARTICIPATION OF CYTOCHROME B5 IN HEPATIC MICROSOMAL MIXED-FUNCTION OXIDASE REACTION	34	33
714	14	2499 1974 DRUG METABOLISM AND DISPOSITION 2(3):321-326 FRANKLIN MR INFLUENCE OF CYTOCHROME-P-450 INDUCTION ON METABOLIC FORMATION OF 455-NM COMPLEXES FROM AMPHETAMINES	53	33
715	11	2630 1974 XENOBIOTICA 4(3):133-142 FRANKLIN MR COMPLEXES OF METABOLITES OF AMPHETAMINES WITH HEPATIC CYTOCHROME-P-450	54	33
716	21	3135 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(19):6068-6074 WANG HP; KIMURA T PURIFICATION AND CHARACTERIZATION OF ADRENAL-CORTEX MITOCHONDRIAL CYTOCHROME-P-450 SPECIFIC FOR CHOLESTEROL SIDE- CHAIN CLEAVAGE ACTIVITY	73	33
717	19	3964 1979 TOXICOLOGY AND APPLIED PHARMACOLOGY 49(3):437-450 ELCOMBE CR; LECH JJ INDUCTION AND CHARACTERIZATION OF HEMOPROTEIN(S) P-450 AND MONOOXYGENATION IN RAINBOW-TROUT (SALMO-GAIRDNERI)	150	33
718	17	5438 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(14):8397-8403 HALPERT JR; MILLER NE; GORSKY LD ON THE MECHANISM OF THE INACTIVATION OF THE MAJOR PHENOBARBITAL-INDUCIBLE ISOZYME OF RAT-LIVER CYTOCHROME-P-450 BY CHLORAMPHENICOL	67	33
719	26	5548 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 251(1):348-360 WEISS RH; ESTABROOK RW THE MECHANISM OF CUMENE HYDROPEROXIDE-DEPENDENT LIPID- PEROXIDATION - THE FUNCTION OF CYTOCHROME-P-450	33	33
720	7	5555 1986 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 141(3):1007-1011 CAPDEVILA J; YADAGIRI P; MANNA S; FALCK JR ABSOLUTE-CONFIGURATION OF THE HYDROXYEICOSATETRAENOIC ACIDS (HETES) FORMED DURING CATALYTIC OXYGENATION OF ARACHIDONIC-ACID BY MICROSOMAL CYTOCHROME-P-450	106	33
721	4	6233 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(19):9449-9455 TRABER PG; CHIANALE J; FLORENCE R; KIM K; WOJCIK E; GUMUCIO JJ EXPRESSION OF CYTOCHROME-P450B AND CYTOCHROME-P450E GENES IN SMALL INTESTINAL-MUCOSA OF RATS FOLLOWING TREATMENT WITH PHENOBARBITAL, POLYHALOGENATED BIPHENYLS, AND ORGANOCHLORINE PESTICIDES	77	33
722	2	6258 1988 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 245(3):845-849 KNODELL RG; DUBEY RK; WILKINSON GR; GUENGERICH FP OXIDATIVE-METABOLISM OF HEXOBARBITAL IN HUMAN-LIVER - RELATIONSHIP TO POLYMORPHIC S-MEPHENYTOIN 4-HYDROXYLATION	71	33
723	11	6379 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 270(2):458-471 ARLOTTO MP; PARKINSON A IDENTIFICATION OF CYTOCHROME-P450A (P450IIA1) AS THE PRINCIPAL TESTOSTERONE 7-ALPHA-HYDROXYLASE IN RAT-LIVER MICROSOMES AND ITS REGULATION BY THYROID-HORMONES	52	33
724	15	6626 1989 JOURNAL OF BIOCHEMISTRY 105(6):939-945 IMAOKA S; TERANO Y; FUNAE Y EXPRESSION OF 4 PHENOBARBITAL-INDUCIBLE CYTOCHROME-P-450S IN LIVER, KIDNEY, AND LUNG OF RATS	73	33
725	23	8970 1994 BIOCHEMICAL PHARMACOLOGY 48(1):59-64 HAKKOLA J; PASANEN M; PURKUNEN R; SAARIKOSKI S; PELKONEN O; MAENPAA J; RANE A; RAUNIO H EXPRESSION OF XENOBIOTIC-METABOLIZING CYTOCHROME-P450 FORMS IN HUMAN ADULT AND FETAL LIVER	95	33
726	16	9090 1994 DRUG METABOLISM AND DISPOSITION 22(5):688-692 BUTERS JTM; KORZEKWA KR; KUNZE KL; OMATA Y; HARDWICK JP; GONZALEZ FJ CDNA-DIRECTED EXPRESSION OF HUMAN CYTOCHROME-P450 CYP3A4 USING BACULOVIRUS	55	33
727	24	10313 1996 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 277(1):321-332 Bourrie M; Meunier V; Berger Y; Fabre G Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes	153	33
728	6	10879 1997 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 94(16):8411-8416 Wang M; Roberts DL; Paschke R; Shea TM; Masters BSS; Kim JJP Three-dimensional structure of NADPH-cytochrome P450 reductase: Prototype for FMN- and FAD-containing enzymes	152	33
729	54	11466 1999 ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY 39():1-17 Guengrich FP Cytochrome P-450 3A4: Regulation and role in drug metabolism	124	33
730	23	11482 1999 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 369(1):1-10 Nelson DR Cytochrome P450 and the individuality of species	99	33
731	1	28 1958 BIOCHEMICAL JOURNAL 68():283-295 CHANCE B; BALTSCHEFFSKY M SPECTROSCOPIC EFFECTS OF ADENOSINE DIPHOSPHATE UPON THE RESPIRATORY PIGMENTS OF RAT-HEART-MUSCLE SARCOSOMES	148	32
732	2	47 1959 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 80(1):68-71 SACKTOR B; PACKER L; ESTABROOK RW RESPIRATORY ACTIVITY OF BRAIN MITOCHONDRIA	32	32
733	2	107 1960 JOURNAL OF BIOLOGICAL CHEMISTRY 235(3):845-852 YONETANI T STUDIES ON CYTOCHROME OXIDASE .1. ABSOLUTE AND DIFFERENCE ABSORPTION SPECTRA	323	32
734	2	622 1967 BIOCHEMICAL PHARMACOLOGY 16(1):99-& RAY JW EPOXIDATION OF ALDRIN BY HOUSEFLY MICROSOMES AND ITS INHIBITION BY CARBON MONOXIDE	83	32
735	1	767 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 126(3):977-& SIMPSON ER; ESTABROOK RW A POSSIBLE MECHANISM FOR TRANSFER OF CYTOSOL-GENERATED NADPH TO MITOCHONDRIAL MIXED-FUNCTION OXIDASES IN BOVINE ADRENAL CORTEX - A MALATE SHUTTLE	32	32
736	9	921 1968 MOLECULAR PHARMACOLOGY 4(2):109-& KATO R; TAKAHASH.A THYROID HORMONE AND ACTIVITIES OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEMS OF RAT LIVER MICROSOMES	108	32
737	4	1174 1969 STEROIDS 13(3):327-& JACOBSON M; KUNTZMAN R STUDIES ON TESTOSTERONE HYDROXYLATION AND PENTOBARBITAL OXIDATION BY RAT LIVER MICROSOMES - SELECTIVE EFFECTS OF AGE SEX CASTRATION AND TESTOSTERONE PROPIONATE TREATMENT	74	32
738	7	1242 1970 BIOCHEMICAL PHARMACOLOGY 19(7):2396-& SCHENKMAN JB; CINTI DL RATE-LIMITING STEP IN AMINOPYRINE DEMETHYLASE OF RAT LIVER MICROSOMES	46	32
739	3	1840 1972 BIOCHIMIE 54(4):483-& POMMIER J; PRAILAUN.SD; NUNEZ J PARTICULAR THYROID PEROXYDASE	69	32
740	20	1896 1972 FEDERATION PROCEEDINGS 31(4):1315-& NEBERT DW; GIELEN JE GENETIC REGULATION OF ARYL HYDROCARBON HYDROXYLASE INDUCTION IN MOUSE	222	32
741	32	2295 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(22):7637-7647 NEBERT DW; ROBINSON JR; KON H FURTHER STUDIES ON GENETICALLY MEDIATED DIFFERENCES IN MONOOXYGENASE ACTIVITIES AND SPIN STATE OF CYTOCHROME P450 IRON FROM RABBIT, RAT, AND MOUSE LIVER	62	32
742	5	2807 1975 FEBS LETTERS 50(3):378-381 ELLIN A; ORRENIUS S HYDROPEROXIDE-SUPPORTED CYTOCHROME P-450-LINKED FATTY-ACID HYDROXYLATION IN LIVER-MICROSOMES	56	32
743	10	2957 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 173(1):178-186 SHIGEMATSU H; YAMANO S; YOSHIMURA H NADH-DEPENDENT O-DEETHYLATION OF P-NITROPHENETOLE WITH RABBIT LIVER-MICROSOMES	62	32
744	64	3464 1977 XENOBIOTICA 7(1-2):25-92 KATO R DRUG-METABOLISM UNDER PATHOLOGICAL AND ABNORMAL PHYSIOLOGICAL STATES IN ANIMALS AND MAN	236	32
745	15	3639 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(23):8355-8358 SEYBERT DW; LAMBETH JD; KAMIN H PARTICIPATION OF A 2ND MOLECULE OF ADRENODOXIN IN CYTOCHROME P- 450-CATALYZED 11-BETA HYDROXYLATION	53	32
746	11	3880 1979 JOURNAL OF BIOLOGICAL CHEMISTRY 254(8):2766-2774 LAMBETH JD; KAMIN H ADRENODOXIN REDUCTASE - ADRENODOXIN COMPLEX - FLAVIN TO IRON- SULFUR ELECTRON-TRANSFER AS THE RATE-LIMITING STEP IN THE NADPH-CYTOCHROME-C REDUCTASE REACTION	90	32
747	14	4282 1981 BIOCHEMICAL PHARMACOLOGY 30(6):553-558 PESSAYRE D; DESCATOIRE V; KONSTANTINOVAMITCHEVA M; WANDSCHEER JC; COBERT B; LEVEL R; BENHAMOU JP; JAOUEN M; MANSUY D SELF-INDUCTION BY TRIACETYLOLEANDOMYCIN OF ITS OWN TRANSFORMATION INTO A METABOLITE FORMING A STABLE 456-NM- ABSORBING COMPLEX WITH CYTOCHROME-P-450	123	32
748	5	4516 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 108(2):454-460 ONODA M; HALL PF CYTOCHROME-B5 STIMULATES PURIFIED TESTICULAR MICROSOMAL CYTOCHROME-P-450 (C21 SIDE-CHAIN CLEAVAGE)	69	32
749	9	5766 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 258(2):630-635 LEVIN W; THOMAS PE; RYAN DE; WOOD AW ISOZYME SPECIFICITY OF TESTOSTERONE 7-ALPHA-HYDROXYLATION IN RAT HEPATIC MICROSOMES - IS CYTOCHROME P-450A THE SOLE CATALYST	43	32
750	7	5887 1987 EMBO JOURNAL 6(7):1929-1933 KIMURA S; SMITH HH; HANKINSON O; NEBERT DW ANALYSIS OF 2 BENZO[A]PYRENE-RESISTANT MUTANTS OF THE MOUSE HEPATOMA HEPA-1 P1450 GENE VIA CDNA EXPRESSION IN YEAST	70	32
751	2	6277 1988 MOLECULAR ENDOCRINOLOGY 2(6):564-570 KAGIMOTO M; WINTER JSD; KAGIMOTO K; SIMPSON ER; WATERMAN MR STRUCTURAL CHARACTERIZATION OF NORMAL AND MUTANT HUMAN STEROID 17-ALPHA-HYDROXYLASE GENES - MOLECULAR-BASIS OF ONE EXAMPLE OF COMBINED 17-ALPHA-HYDROXYLASE/17,20 LYASE DEFICIENCY	75	32
752	16	7060 1990 EUROPEAN JOURNAL OF BIOCHEMISTRY 194(3):889-896 RENAUD JP; CULLIN C; POMPON D; BEAUNE P; MANSUY D EXPRESSION OF HUMAN LIVER CYTOCHROME-P450 IIIA4 IN YEAST - A FUNCTIONAL-MODEL FOR THE HEPATIC ENZYME	79	32
753	7	7123 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(2):1188-1192 SCHUETZ EG; SCHUETZ JD; MAY B; GUZELIAN PS REGULATION OF CYTOCHROME-P-450B/E AND P-450P GENE-EXPRESSION BY GROWTH-HORMONE IN ADULT-RAT HEPATOCYTES CULTURED ON A RECONSTITUTED BASEMENT-MEMBRANE	105	32
754	9	7164 1990 JOURNAL OF CLINICAL INVESTIGATION 85(6):1967-1973 BOURDI M; LARREY D; NATAF J; BERNUAU J; PESSAYRE D; IWASAKI M; GUENGERICH FP; BEAUNE PH ANTI-LIVER ENDOPLASMIC-RETICULUM AUTOANTIBODIES ARE DIRECTED AGAINST HUMAN CYTOCHROME-P-4501A2 - A SPECIFIC MARKER OF DIHYDRALAZINE-INDUCED HEPATITIS	116	32
755	3	7190 1990 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 35(2):333-342 FRENKEL RA; SLAUGHTER CA; ORTH K; MOOMAW CR; HICKS SH; SNYDER JM; BENNETT M; PROUGH RA; PUTNAM RS; MILEWICH L PEROXISOME PROLIFERATION AND INDUCTION OF PEROXISOMAL ENZYMES IN MOUSE AND RAT-LIVER BY DEHYDROEPIANDROSTERONE FEEDING	77	32
756	16	7563 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 200(2):511-517 MAURICE M; EMILIANI S; DALETBELUCHE I; DERANCOURT J; LANGE R ISOLATION AND CHARACTERIZATION OF A CYTOCHROME-P450 OF THE IIA SUBFAMILY FROM HUMAN LIVER-MICROSOMES	53	32
757	9	7723 1991 MOLECULAR ENDOCRINOLOGY 5(12):1853-1861 DOMALIK LJ; CHAPLIN DD; KIRKMAN MS; WU RC; LIU WW; HOWARD TA; SELDIN MF; PARKER KL DIFFERENT ISOZYMES OF MOUSE 11-BETA-HYDROXYLASE PRODUCE MINERALOCORTICOIDS AND GLUCOCORTICOIDS	111	32
758	6	8306 1992 PLANT PHYSIOLOGY 100(2):998-1007 VETTER HP; MANGOLD U; SCHRODER G; MARNER FJ; WERCKREICHHART D; SCHRODER J MOLECULAR ANALYSIS AND HETEROLOGOUS EXPRESSION OF AN INDUCIBLE CYTOCHROME-P-450 PROTEIN FROM PERIWINKLE (CATHARANTHUS-ROSEUS L)	72	32
759	6	8317 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(22):10920-10924 COHEN MB; SCHULER MA; BERENBAUM MR A HOST-INDUCIBLE CYTOCHROME-P-450 FROM A HOST-SPECIFIC CATERPILLAR - MOLECULAR-CLONING AND EVOLUTION	69	32
760	7	8416 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 307(2):253-258 KIRITA S; MATSUBARA T CDNA CLONING AND CHARACTERIZATION OF A NOVEL MEMBER OF STEROID- INDUCED CYTOCHROME-P450 3A IN RATS	46	32
761	14	8684 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(13):9376-9380 KIKUTA Y; KUSUNOSE E; ENDO K; YAMAMOTO S; SOGAWA K; FUJIIKURIYAMA Y; KUSUNOSE M A NOVEL FORM OF CYTOCHROME-P-450 FAMILY-4 IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES - CDNA CLONING AND EXPRESSION OF LEUKOTRIENE-B4 OMEGA-HYDROXYLASE	68	32
762	20	8802 1993 PHARMACOGENETICS 3(5):213-230 SWANSON HI; BRADFIELD CA THE AH-RECEPTOR - GENETICS, STRUCTURE AND FUNCTION	274	32
763	11	9870 1995 PROTEIN SCIENCE 4(6):1065-1080 GRAHAMLORENCE S; AMARNEH B; WHITE RE; PETERSON JA; SIMPSON ER A 3-DIMENSIONAL MODEL OF AROMATASE CYTOCHROME-P450	93	32
764	12	185 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(10):3259-& SACKTOR B; DICK A PATHWAYS OF HYDROGEN TRANSPORT IN OXIDATION OF EXTRAMITOCHONDRIAL REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE IN FLIGHT MUSCLE	95	31
765	6	240 1963 JOURNAL OF BIOLOGICAL CHEMISTRY 238(4):1529-& MINAKAMI S; SINGER TP; RINGLER RL; CREMONA T STUDIES ON RESPIRATORY CHAIN-LINKED REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE .3. CATALYTIC PROPERTIES OF ENZYME FROM BEEF HEART	71	31
766	12	421 1965 JOURNAL OF BIOLOGICAL CHEMISTRY 240(6):2729-& CHANCE B ENERGY-LINKED REACTION OF CALCIUM WITH MITOCHONDRIA	505	31
767	9	423 1965 JOURNAL OF BIOLOGICAL CHEMISTRY 240(7):3170-& CHANCE B; SCHOENER B; ELSAESSE.S METABOLIC CONTROL PHENOMENA INVOLVED IN DAMPED SINUSOIDAL OSCILLATIONS OF REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE IN A CELL- FREE EXTRACT OF SACCHAROMYCES CARLSBERGENSIS	89	31
768	4	876 1968 JOURNAL OF BIOCHEMISTRY 64(1):109-& WADA F; SHIMAKAW.H; TAKASUGI M; KOTAKE T; SAKAMOTO Y EFFECTS OF STEROID HORMONES ON DRUG-METABOLIZING ENZYME SYSTEMS IN LIVER MICROSOMES	63	31
769	4	936 1968 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 61(2):748-& TENHUNEN R; MARVER HS; SCHMID R ENZYMATIC CONVERSION OF HEME TO BILIRUBIN BY MICROSOMAL HEME OXYGENASE	488	31
770	6	996 1969 BIOCHEMICAL JOURNAL 113(4):681-& GRAM TE; GUARINO AM; SCHROEDE.DH; GILLETTE JR CHANGES IN CERTAIN KINETIC PROPERTIES OF HEPATIC MICROSOMAL ANILINE HYDROXYLASE AND ETHYLMORPHINE DEMETHYLASE ASSOCIATED WITH POSTNATAL DEVELOPMENT AND MATURATION IN MALE RATS	93	31
771	14	1386 1970 MOLECULAR PHARMACOLOGY 6(3):221-& KUPFER D; ORRENIUS S CHARACTERISTICS OF GUINEA-PIG LIVER AND ADRENAL MONOOXYGENASE SYSTEMS	62	31
772	0	1398 1970 PHARMACOLOGIST 12(2):261-& RAJ P; ESTABROOK RW DETERMINATION OF CYTOCHROME P-450 CONTENT OF SMALL SAMPLES OF LIVER	31	31
773	9	1579 1971 EUROPEAN JOURNAL OF BIOCHEMISTRY 21(3):308-& MASON JI; BOYD GS CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME SYSTEM IN MITOCHONDRIA OF HUMAN TERM PLACENTA	85	31
774	11	1669 1971 METABOLISM-CLINICAL AND EXPERIMENTAL 20(2):215-& GILLETTE JR EFFECT OF VARIOUS INDUCERS ON ELECTRON TRANSPORT SYSTEM ASSOCIATED WITH DRUG METABOLISM BY LIVER MICROSOMES	64	31
775	13	1883 1972 EUROPEAN JOURNAL OF BIOCHEMISTRY 28(3):442-& SIMPSON ER; BOYD GS; BROWNIE AC; JEFCOATE CR EFFECT OF ETHER ANESTHESIA STRESS ON CHOLESTEROL-SIDE-CHAIN CLEAVAGE AND CYTOCHROME P450 IN RAT-ADRENAL MITOCHONDRIA	133	31
776	6	2070 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 158(2):597-604 ELLIN A; ORRENIUS S CYTOCHROME P-450K OF RAT-KIDNEY CORTEX MICROSOMES - FURTHER STUDIES ON ITS INTERACTION WITH FATTY-ACIDS	69	31
777	7	2705 1975 BIOCHEMICAL PHARMACOLOGY 24(15):1427-1433 ELCOMBE CR; BRIDGES JW; GRAY TJB; NIMMOSMITH RH; NETTER KJ STUDIES ON INTERACTION OF SAFROLE WITH RAT HEPATIC MICROSOMES	71	31
778	1	3128 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(11):3442-3446 MIEYAL JJ; BLUMER JL ACCELERATION OF AUTOOXIDATION OF HUMAN OXYHEMOGLOBIN BY ANILINE AND ITS RELATION TO HEMOGLOBIN-CATALYZED ANILINE HYDROXYLATION	101	31
779	14	3399 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(13):4431-4434 PETERSON JA; WHITE RE; YASUKOCHI Y; COOMES ML; OKEEFFE DH; EBEL RE; MASTERS BSS; BALLOU DP; COON MJ EVIDENCE THAT PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450 IS A ONE-ELECTRON ACCEPTOR	54	31
780	11	3755 1979 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 91(1):207-213 NOSHIRO M; HARADA N; OMURA T IMMUNOCHEMICAL STUDY ON THE PARTICIPATION OF CYTOCHROME-B5 IN DRUG OXIDATION REACTIONS OF MOUSE-LIVER MICROSOMES	35	31
781	26	4548 1982 BIOCHEMISTRY 21(6):1324-1330 BACKES WL; SLIGAR SG; SCHENKMAN JB KINETICS OF HEPATIC CYTOCHROME-P-450 REDUCTION - CORRELATION WITH SPIN STATE OF THE FERRIC HEME	50	31
782	4	5273 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 237(2):465-476 HINES RN; LEVY JB; CONRAD RD; IVERSEN PL; SHEN ML; RENLI AM; BRESNICK E GENE STRUCTURE AND NUCLEOTIDE-SEQUENCE FOR RAT CYTOCHROME-P- 450C	66	31
783	17	5801 1987 BIOCHEMICAL PHARMACOLOGY 36(24):4277-4281 RODRIGUES AD; GIBSON GG; IOANNIDES C; PARKE DV INTERACTIONS OF IMIDAZOLE ANTIFUNGAL AGENTS WITH PURIFIED CYTOCHROME-P-450 PROTEINS	96	31
784	8	5918 1987 JOURNAL OF BIOLOGICAL CHEMISTRY 262(29):14319-14326 FAVREAU LV; MALCHOFF DM; MOLE JE; SCHENKMAN JB RESPONSES TO INSULIN BY 2 FORMS OF RAT HEPATIC-MICROSOMAL CYTOCHROME-P-450 THAT UNDERGO MAJOR (RLM6) AND MINOR (RLM5B) ELEVATIONS IN DIABETES	76	31
785	3	6179 1988 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7(10):701-711 YABUSAKI Y; MURAKAMI H; SAKAKI T; SHIBATA M; OHKAWA H GENETICALLY ENGINEERED MODIFICATION OF P450 MONOOXYGENASES - FUNCTIONAL-ANALYSIS OF THE AMINO-TERMINAL HYDROPHOBIC REGION AND HINGE REGION OF THE P450/REDUCTASE FUSED ENZYME	58	31
786	5	6199 1988 EUROPEAN JOURNAL OF BIOCHEMISTRY 177(2):285-293 POMPON D CDNA CLONING AND FUNCTIONAL EXPRESSION IN YEAST SACCHAROMYCES- CEREVISIAE OF BETA-NAPHTHOFLAVONE-INDUCED RABBIT LIVER P-450- LM4 AND P-450-LM6	63	31
787	6	6300 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(3):699-703 ZUBER MX; MASON JI; SIMPSON ER; WATERMAN MR SIMULTANEOUS TRANSFECTION OF COS-1 CELLS WITH MITOCHONDRIAL AND MICROSOMAL STEROID HYDROXYLASES - INCORPORATION OF A STEROIDOGENIC PATHWAY INTO NONSTEROIDOGENIC CELLS	63	31
788	4	6302 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(5):1600-1604 AMOR M; PARKER KL; GLOBERMAN H; NEW MI; WHITE PC MUTATION IN THE CYP21B GENE (ILE-172-]ASN) CAUSES STEROID 21- HYDROXYLASE DEFICIENCY	145	31
789	20	6388 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(1):42-57 HONKAKOSKI P; LANG MA MOUSE-LIVER PHENOBARBITAL-INDUCIBLE P450 SYSTEM - PURIFICATION, CHARACTERIZATION, AND DIFFERENTIAL INDUCIBILITY OF 4 CYTOCHROME-P450 ISOZYMES FROM THE D2 MOUSE	65	31
790	12	6444 1989 BIOCHEMICAL PHARMACOLOGY 38(20):3621-3629 SHARMA RK; DOIG MV; LEWIS DFV; GIBSON GG ROLE OF HEPATIC AND RENAL CYTOCHROME-P-450 IVA1 IN THE METABOLISM OF LIPID SUBSTRATES	51	31
791	9	6605 1989 GENE 76(1):121-136 SANGLARD D; LOPER JC CHARACTERIZATION OF THE ALKANE-INDUCIBLE CYTOCHROME-P450 (P450ALK) GENE FROM THE YEAST CANDIDA-TROPICALIS - IDENTIFICATION OF A NEW P450-GENE FAMILY	51	31
792	3	6696 1989 MOLECULAR AND CELLULAR BIOLOGY 9(6):2378-2386 NEUHOLD LA; SHIRAYOSHI Y; OZATO K; JONES JE; NEBERT DW REGULATION OF MOUSE CYP1A1 GENE-EXPRESSION BY DIOXIN - REQUIREMENT OF 2 CIS-ACTING ELEMENTS DURING INDUCTION	122	31
793	12	6710 1989 MOLECULAR PHARMACOLOGY 35(4):519-525 WAXMAN DJ; MORRISSEY JJ; LEBLANC GA HYPOPHYSECTOMY DIFFERENTIALLY ALTERS P-450 PROTEIN-LEVELS AND ENZYME-ACTIVITIES IN RAT-LIVER - PITUITARY CONTROL OF HEPATIC NADPH CYTOCHROME-P-450 REDUCTASE	69	31
794	6	6781 1989 TRENDS IN PHARMACOLOGICAL SCIENCES 10(4):149-153 ZAPHIROPOULOS PG; MODE A; NORSTEDT G; GUSTAFSSON JA REGULATION OF SEXUAL-DIFFERENTIATION IN DRUG AND STEROID- METABOLISM	105	31
795	18	6809 1990 AMERICAN JOURNAL OF PHYSIOLOGY 258(4):F781-F789 TAKAHASHI K; CAPDEVILA J; KARARA A; FALCK JR; JACOBSON HR; BADR KF CYTOCHROME-P-450 ARACHIDONATE METABOLITES IN RAT-KIDNEY - CHARACTERIZATION AND HEMODYNAMIC-RESPONSES	114	31
796	13	6917 1990 BIOCHEMISTRY 29(35):8119-8126 RAAG R; SWANSON BA; POULOS TL; DEMONTELLANO PRO FORMATION, CRYSTAL-STRUCTURE, AND REARRANGEMENT OF A CYTOCHROME-P-450CAM IRON PHENYL COMPLEX	61	31
797	11	6979 1990 CARCINOGENESIS 11(7):1183-1188 SESARDIC D; PASANEN M; PELKONEN O; BOOBIS AR DIFFERENTIAL EXPRESSION AND REGULATION OF MEMBERS OF THE CYTOCHROME-P450IA GENE SUBFAMILY IN HUMAN TISSUES	84	31
798	5	7469 1991 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 31(2):125-130 DOECKE CJ; VERONESE ME; POND SM; MINERS JO; BIRKETT DJ; SANSOM LN; MCMANUS ME RELATIONSHIP BETWEEN PHENYTOIN AND TOLBUTAMIDE HYDROXYLATIONS IN HUMAN LIVER-MICROSOMES	98	31
799	5	7527 1991 DNA AND CELL BIOLOGY 10(7):487-494 BURCHELL B; NEBERT DW; NELSON DR; BOCK KW; IYANAGI T; JANSEN PLM; LANCET D; MULDER GJ; CHOWDHURY JR; SIEST G; TEPHLY TR; MACKENZIE PI THE UDP GLUCURONOSYLTRANSFERASE GENE SUPERFAMILY - SUGGESTED NOMENCLATURE BASED ON EVOLUTIONARY DIVERGENCE	247	31
800	11	8099 1992 FASEB JOURNAL 6(2):680-685 BLACK SD MEMBRANE TOPOLOGY OF THE MAMMALIAN P450-CYTOCHROMES	61	31

#	Cited nodes	Nodes / Authors	GCS	LCS
801	24	9095 1994 DRUG METABOLISM AND DISPOSITION 22(6):947-955 LOWN KS; KOLARS JC; THUMMEL KE; BARNETT JL; KUNZE KL; WRIGHTON SA; WATKINS PB INTERPATIENT HETEROGENEITY IN EXPRESSION OF CYP3A4 AND CYP3A5 IN SMALL-BOWEL - LACK OF PREDICTION BY THE ERYTHROMYCIN BREATH TEST	175	31
802	45	11126 1998 CLINICAL PHARMACOKINETICS 35(5):361-390 Lin JH; Lu AYH Inhibition and induction of cytochrome P450 and the clinical implications	122	31
803	3	105 1960 JOURNAL OF BIOLOGICAL CHEMISTRY 235(2):531-534 JACOBS EE; SANADI DR REVERSIBLE REMOVAL OF CYTOCHROME-C FROM MITOCHONDRIA	291	30
804	2	830 1968 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY 25(1):223-& BUHLER DR; RASMUSSO.ME OXIDATION OF DRUGS BY FISHES	145	30
805	7	976 1969 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 134(2):486-& SAUER LA; MULROW PJ STEROID HYDROXYLATIONS IN RAT ADRENAL MITOCHONDRIA .I. SOME PROPERTIES OF C-18 AND 11-BETA HYDROXYLATIONS IN TIGHTLY COUPLED MITOCHONDRIA	63	30
806	14	1025 1969 BIOCHIMICA ET BIOPHYSICA ACTA 171(1):32-& ICHIKAWA Y; YAMANO T; FUJISHIM.H RELATIONSHIP BETWEEN INTERCONVERSION OF CYTOCHROME P-450 AND P- 420 AND ITS ACTIVITIES IN HYDROXYLATIONS AND DEMETHYLATIONS BY P-450 OXIDASE SYSTEMS	63	30
807	6	1776 1972 BIOCHEMICAL GENETICS 6(2-3):157-& THOMAS PE; KOURI RE; HUTTON JJ GENETICS OF ARYL HYDROCARBON HYDROXYLASE INDUCTION IN MICE - SINGLE GENE DIFFERENCE BETWEEN C57BL/6J AND DBA/2J	205	30
808	34	2277 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(1):169-178 NEBERT DW; KON H GENETIC REGULATION OF ARYL HYDROCARBON HYDROXYLASE INDUCTION .5. SPECIFIC CHANGES IN SPIN STATE OF CYTOCHROME-P450 FROM GENETICALLY RESPONSIVE ANIMALS	63	30
809	13	2431 1974 BIOCHEMICAL PHARMACOLOGY 23(8):1319-1329 JONEN HG; HUTHWOHL B; KAHL R; KAHL GF INFLUENCE OF PYRIDINE AND SOME PYRIDINE-DERIVATIVES ON SPECTRAL PROPERTIES OF REDUCED MICROSOMES AND ON MICROSOMAL DRUG- METABOLIZING ACTIVITY	55	30
810	29	2657 1975 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 244(APR15):107-131 GRIFFIN BW; PETERSON JA; WERRINGLOER J; ESTABROOK RW CHEMISTRY OF SOLUBLE AND MEMBRANE-BOUND CYTOCHROME-P-450	30	30
811	24	2887 1975 MOLECULAR PHARMACOLOGY 11(4):450-461 JANSSON I; SCHENKMAN JB STUDIES ON 3 MICROSOMAL ELECTRON-TRANSFER ENZYME-SYSTEMS - EFFECTS OF ALTERATION OF COMPONENT ENZYME LEVELS INVIVO AND INVITRO	80	30
812	5	3244 1977 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 180(2):363-373 PROUGH RA; ZIEGLER DM RELATIVE PARTICIPATION OF LIVER MICROSOMAL AMINE OXIDASE AND CYTOCHROME-P-450 IN N-DEMETHYLATION REACTIONS	153	30
813	7	3277 1977 BIOCHEMICAL PHARMACOLOGY 26(11):1039-1042 ROGERSON TD; WILKINSON CF; HETARSKI K STERIC FACTORS IN INHIBITORY INTERACTION OF IMIDAZOLES WITH MICROSOMAL-ENZYMES	103	30
814	28	3634 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(17):5957-5963 GIBSON GG; SCHENKMAN JB PURIFICATION AND PROPERTIES OF CYTOCHROME-P-450 OBTAINED FROM LIVER-MICROSOMES OF UNTREATED RATS BY LAURIC ACID AFFINITY CHROMATOGRAPHY	83	30
815	20	5373 1985 DRUG METABOLISM AND DISPOSITION 13(4):453-458 JANSSON I; TAMBURINI PP; FAVREAU LV; SCHENKMAN JB THE INTERACTION OF CYTOCHROME-B5 WITH 4 CYTOCHROME-P-450 ENZYMES FROM THE UNTREATED RAT	58	30
816	10	5760 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 252(1):334-338 WEISS RH; ARNOLD JL; ESTABROOK RW TRANSFORMATION OF AN ARACHIDONIC-ACID HYDROPEROXIDE INTO EPOXYHYDROXY AND TRIHYDROXY FATTY-ACIDS BY LIVER MICROSOMAL CYTOCHROME-P-450	30	30
817	2	6057 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 156(2):725-732 HARADA N CLONING OF A COMPLETE CDNA-ENCODING HUMAN AROMATASE - IMMUNOCHEMICAL IDENTIFICATION AND SEQUENCE-ANALYSIS	132	30
818	4	6064 1988 BIOCHEMICAL JOURNAL 254(3):789-797 MEEHAN RR; FORRESTER LM; STEVENSON K; HASTIE ND; BUCHMANN A; KUNZ HW; WOLF CR REGULATION OF PHENOBARBITAL-INDUCIBLE CYTOCHROME-P-450S IN RAT AND MOUSE-LIVER FOLLOWING DEXAMETHASONE ADMINISTRATION AND HYPOPHYSECTOMY	67	30
819	12	6241 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(32):17197-17202 MURPHY RC; FALCK JR; LUMIN S; YADAGIRI P; ZIRROLLI JA; BALAZY M; MASFERRER JL; ABRAHAM NG; SCHWARTZMAN ML 12(R)-HYDROXYEICOSATRIENOIC ACID - A VASODILATOR CYTOCHROME-P- 450-DEPENDENT ARACHIDONATE METABOLITE FROM THE BOVINE CORNEAL EPITHELIUM	93	30
820	9	6383 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 271(2):284-299 CIACCIO PJ; HALPERT JR CHARACTERIZATION OF A PHENOBARBITAL-INDUCIBLE DOG LIVER CYTOCHROME-P450 STRUCTURALLY RELATED TO RAT AND HUMAN ENZYMES OF THE P450IIIA (STEROID-INDUCIBLE) GENE SUBFAMILY	64	30
821	6	6643 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(27):16222-16228 POTENZA CL; PENDURTHI UR; STROM DK; TUKEY RH; GRIFFIN KJ; SCHWAB GE; JOHNSON EF REGULATION OF THE RABBIT CYTOCHROME-P-450 3C GENE - AGE- DEPENDENT EXPRESSION AND TRANSCRIPTIONAL ACTIVATION BY RIFAMPICIN	50	30
822	7	6701 1989 MOLECULAR CARCINOGENESIS 2(4):192-198 AOYAMA T; GONZALEZ FJ; GELBOIN HV HUMAN CDNA-EXPRESSED CYTOCHROME-P450 IA2 - MUTAGEN ACTIVATION AND SUBSTRATE-SPECIFICITY	72	30
823	10	7528 1991 DNA AND CELL BIOLOGY 10(8):545-558 BROLY F; GAEDIGK A; HEIM M; EICHELBAUM M; MORIKE K; MEYER UA DEBRISOQUINE SPARTEINE HYDROXYLATION GENOTYPE AND PHENOTYPE - ANALYSIS OF COMMON MUTATIONS AND ALLELES OF CYP2D6 IN A EUROPEAN POPULATION	201	30
824	11	7623 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(12):7774-7778 CALI JJ; RUSSELL DW CHARACTERIZATION OF HUMAN STEROL 27-HYDROXYLASE - A MITOCHONDRIAL CYTOCHROME-P-450 THAT CATALYZES MULTIPLE OXIDATION REACTIONS IN BILE-ACID BIOSYNTHESIS	134	30
825	8	7630 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(18):11939-11946 GRAHAMLORENCE S; KHALIL MW; LORENCE MC; MENDELSON CR; SIMPSON ER STRUCTURE-FUNCTION-RELATIONSHIPS OF HUMAN AROMATASE CYTOCHROME- P-450 USING MOLECULAR MODELING AND SITE-DIRECTED MUTAGENESIS	81	30
826	11	7763 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(15):6868-6872 WAXMAN DJ; PAMPORI NA; RAM PA; AGRAWAL AK; SHAPIRO BH INTERPULSE INTERVAL IN CIRCULATING GROWTH-HORMONE PATTERNS REGULATES SEXUALLY DIMORPHIC EXPRESSION OF HEPATIC CYTOCHROME- P450	141	30
827	13	7857 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 294(1):206-214 SCHUETZ EG; SCHUETZ JD; GROGAN WM; NARAYFEJESTOTH A; FEJESTOTH G; RAUCY J; GUZELIAN P; GIONELA K; WATLINGTON CO EXPRESSION OF CYTOCHROME-P450 3A IN AMPHIBIAN, RAT, AND HUMAN KIDNEY	62	30
828	13	8346 1992 TRENDS IN PHARMACOLOGICAL SCIENCES 13(3):122-126 JOHNSON EF MAPPING DETERMINANTS OF THE SUBSTRATE SELECTIVITIES OF P450 ENZYMES BY SITE-DIRECTED MUTAGENESIS	50	30
829	15	8513 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1168(1):30-36 SAWAMURA A; KUSUNOSE E; SATOUCHI K; KUSUNOSE M CATALYTIC PROPERTIES OF RABBIT KIDNEY FATTY-ACID OMEGA- HYDROXYLASE CYTOCHROME-P-450KA2 (CYP4A7)	41	30
830	13	8605 1993 ENDOCRINOLOGY 132(6):2498-2506 LIN D; BLACK SM; NAGAHAMA Y; MILLER WL STEROID 17-ALPHA-HYDROXYLASE AND 17,20-LYASE ACTIVITIES OF P450C17 - CONTRIBUTIONS OF SERINE(106) AND P450 REDUCTASE	76	30
831	8	8758 1993 LIFE SCIENCES 52(1):29-34 LEEMANN T; TRANSON C; DAYER P CYTOCHROME-P450TB (CYP2C) - A MAJOR MONOOXYGENASE CATALYZING DICLOFENAC 4'-HYDROXYLATION IN HUMAN LIVER	131	30
832	14	8825 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(7):2651-2655 PERNECKY SJ; LARSON JR; PHILPOT RM; COON MJ EXPRESSION OF TRUNCATED FORMS OF LIVER MICROSOMAL P450 CYTOCHROMES 2B4 AND 2E1 IN ESCHERICHIA-COLI - INFLUENCE OF NH2- TERMINAL REGION ON LOCALIZATION IN CYTOSOL AND MEMBRANES	59	30
833	16	8986 1994 BIOCHEMISTRY 33(8):2171-2177 ANDERSEN JF; UTERMOHLEN JG; FEYEREISEN R EXPRESSION OF HOUSE-FLY CYP6A1 AND NADPH-CYTOCHROME P450 REDUCTASE IN ESCHERICHIA-COLI AND RECONSTITUTION OF AN INSECTICIDE-METABOLIZING P450 SYSTEM	46	30
834	20	8989 1994 BIOCHEMISTRY 33(16):4933-4939 SAKAKI T; KOMINAMI S; TAKEMORI S; OHKAWA H; AKIYOSHISHIBATA M; YABUSAKI Y KINETIC-STUDIES ON A GENETICALLY-ENGINEERED FUSED ENZYME BETWEEN RAT CYTOCHROME P4501A1 AND YEAST NADPH-P450 REDUCTASE	51	30
835	12	9031 1994 CANCER RESEARCH 54(2):386-392 CRESTEIL T; MONSARRAT B; ALVINERIE P; TRELUYER JM; VIEIRA I; WRIGHT M TAXOL METABOLISM BY HUMAN LIVER-MICROSOMES - IDENTIFICATION OF CYTOCHROME-P450 ISOZYMES INVOLVED IN ITS BIOTRANSFORMATION	131	30
836	28	9255 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 271(3):1427-1433 DAIKH BE; LASKER JM; RAUCY JL; KOOP DR REGIOSELECTIVE AND STEREOSELECTIVE EPOXIDATION OF ARACHIDONIC- ACID BY HUMAN CYTOCHROMES P450 2C8 AND 2C9	43	30
837	1	18 1957 JOURNAL OF BIOLOGICAL CHEMISTRY 229(2):1091-1103 ESTABROOK RW; MACKLER B ENZYMATIC AND SPECTROPHOTOMETRIC STUDIES OF A REDUCED DIPHOSPHOPYRIDINE NUCLEOTIDE OXIDASE PREPARATION FROM HEART MUSCLE	29	29
838	3	360 1965 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 109(3):579-& BETZ A; CHANCE B INFLUENCE OF INHIBITORS AND TEMPERATURE ON OSCILLATION OF REDUCED PYRIDINE NUCLEOTIDES IN YEAST CELLS	59	29
839	8	1491 1971 BIOCHEMICAL PHARMACOLOGY 20(1):229-& RUBIN E; LIEBER CS; ALVARES AP; LEVIN W; KUNTZMAN R ETHANOL BINDING TO HEPATIC MICROSOMES - ITS INCREASE BY ETHANOL CONSUMPTION	74	29
840	4	2279 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(4):1141-1157 TANAKA M; HANIU M; YASUNOBU KT; KIMURA T AMINO-ACID SEQUENCE OF BOVINE ADRENODOXIN	121	29
841	7	2314 1973 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 184(1):269-277 POLAND AP; NEBERT DW SENSITIVE RADIOMETRIC ASSAY OF AMINOPYRINE N-DEMETHYLATION	98	29
842	30	3238 1977 ANNUAL REVIEW OF BIOCHEMISTRY 46():201-262 DEPIERRE JW; ERNSTER L ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES	339	29
843	11	3438 1977 MOLECULAR PHARMACOLOGY 13(4):698-705 WOLF CR; MANSUY D; NASTAINCZYK W; DEUTSCHMANN G; ULLRICH V REDUCTION OF POLYHALOGENATED METHANES BY LIVER MICROSOMAL CYTOCHROME-P-450	151	29
844	25	4133 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(5):1867-1873 GIBSON GG; CINTI DL; SLIGAR SG; SCHENKMAN JB EFFECT OF MICROSOMAL FATTY-ACIDS AND OTHER LIPIDS ON THE SPIN STATE OF PARTIALLY PURIFIED CYTOCHROME-P-450	43	29
845	44	4204 1980 PHARMACOLOGY & THERAPEUTICS 10(3):515-535 NETTER KJ INHIBITION OF OXIDATIVE DRUG-METABOLISM IN MICROSOMES	122	29
846	12	4307 1981 BIOCHIMICA ET BIOPHYSICA ACTA 664(1):33-48 HIWATASHI A; ICHIKAWA Y PURIFICATION AND RECONSTITUTION OF THE STEROID 21-HYDROXYLASE SYSTEM (CYTOCHROME-P-450-LINKED MIXED-FUNCTION OXIDASE SYSTEM) OF BOVINE ADRENOCORTICAL MICROSOMES	56	29
847	18	4785 1983 BIOCHEMICAL PHARMACOLOGY 32(11):1683-1688 BLANCK J; REIN H; SOMMER M; RISTAU O; SMETTAN G; RUCKPAUL K CORRELATIONS BETWEEN SPIN EQUILIBRIUM SHIFT, REDUCTION RATE, AND N-DEMETHYLATION ACTIVITY IN LIVER MICROSOMAL CYTOCHROME-P- 450 AND A SERIES OF BENZPHETAMINE ANALOGS AS SUBSTRATES	42	29
848	5	4997 1983 TETRAHEDRON LETTERS 24(1):33-36 MANNA S; FALCK JR; CHACOS N; CAPDEVILA J SYNTHESIS OF ARACHIDONIC-ACID METABOLITES PRODUCED BY PURIFIED KIDNEY CORTEX MICROSOMAL CYTOCHROME-P-450	58	29
849	7	6053 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 152(3):1269-1274 ESCALANTE B; FALCK JR; YADAGIRI P; SUN L; LANIADOSCHWARTZMAN M 19(S)-HYDROXYEICOSATETRAENOIC ACID IS A POTENT STIMULATOR OF RENAL NA+-K+-ATPASE	69	29
850	7	6098 1988 BIOCHEMICAL PHARMACOLOGY 37(21):4141-4147 RAUNIO H; KOJO A; JUVONEN R; HONKAKOSKI P; JARVINEN P; LANG MA; VAHAKANGAS K; GELBOIN HV; PARK SS; PELKONEN O MOUSE HEPATIC CYTOCHROME-P-450 ISOZYME INDUCTION BY 1,4-BIS[2- (3,5-DICHLOROPYRIDYLOXY)]BENZENE, PYRAZOLE, AND PHENOBARBITAL	45	29
851	6	6134 1988 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 26(1):23-29 BACK DJ; TJIA JF; KARBWANG J; COLBERT J INVITRO INHIBITION STUDIES OF TOLBUTAMIDE HYDROXYLASE-ACTIVITY OF HUMAN-LIVER MICROSOMES BY AZOLES, SULFONAMIDES AND QUINOLINES	87	29
852	7	6231 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(15):7170-7175 KHANI SC; PORTER TD; FUJITA VS; COON MJ ORGANIZATION AND DIFFERENTIAL EXPRESSION OF 2 HIGHLY SIMILAR GENES IN THE RABBIT ALCOHOL-INDUCIBLE CYTOCHROME-P-450 SUBFAMILY	59	29
853	3	6309 1988 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 85(24):9783-9787 GUZELIAN PS; LI D; SCHUETZ EG; THOMAS P; LEVIN W; MODE A; GUSTAFSSON JA SEX CHANGE IN CYTOCHROME-P-450 PHENOTYPE BY GROWTH-HORMONE TREATMENT OF ADULT-RAT HEPATOCYTES MAINTAINED IN A CULTURE SYSTEM ON MATRIGEL	93	29
854	12	6586 1989 EUROPEAN JOURNAL OF BIOCHEMISTRY 184(1):69-78 SHARMA RK; LAKE BG; MAKOWSKI R; BRADSHAW T; EARNSHAW D; DALE JW; GIBSON GG DIFFERENTIAL INDUCTION OF PEROXISOMAL AND MICROSOMAL FATTY- ACID-OXIDIZING ENZYMES BY PEROXISOME PROLIFERATORS IN RAT-LIVER AND KIDNEY - CHARACTERIZATION OF A RENAL CYTOCHROME-P-450 AND IMPLICATIONS FOR PEROXISOME PROLIFERATION	77	29
855	12	7702 1991 METHODS IN ENZYMOLOGY 206():3-11 NEBERT DW; NELSON DR P450 GENE NOMENCLATURE BASED ON EVOLUTION	45	29
856	10	7711 1991 METHODS IN ENZYMOLOGY 206():441-453 CAPDEVILA JH; DISHMAN E; KARARA A; FALCK JR CYTOCHROME-P450 ARACHIDONIC-ACID EPOXYGENASE - STEREOCHEMICAL CHARACTERIZATION OF EPOXYEICOSATRIENOIC ACIDS	45	29
857	12	7733 1991 MOLECULAR PHARMACOLOGY 40(3):375-382 FURUYA H; MEYER UA; GELBOIN HV; GONZALEZ FJ POLYMERASE CHAIN REACTION-DIRECTED IDENTIFICATION, CLONING, AND QUANTIFICATION OF HUMAN CYP2C18 MESSENGER-RNA	54	29
858	12	7942 1992 BIOCHEMISTRY 31(38):9220-9226 HE YA; BALFOUR CA; KEDZIE KM; HALPERT JR ROLE OF RESIDUE-478 AS A DETERMINANT OF THE SUBSTRATE- SPECIFICITY OF CYTOCHROME-P450-2B1	55	29
859	5	8025 1992 CLINICAL PHARMACOLOGY & THERAPEUTICS 51(3):278-287 SINDRUP SH; BROSEN K; GRAM LF; HALLAS J; SKJELBO E; ALLEN A; ALLEN GD; COOPER SM; MELLOWS G; TASKER TCG; ZUSSMAN BD THE RELATIONSHIP BETWEEN PAROXETINE AND THE SPARTEINE OXIDATION POLYMORPHISM	108	29
860	29	8163 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(8):5552-5559 LAETHEM RM; LAETHEM CL; KOOP DR PURIFICATION AND PROPERTIES OF A CYTOCHROME-P450 ARACHIDONIC- ACID EPOXYGENASE FROM RABBIT RENAL-CORTEX	50	29
861	5	8313 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(10):4653-4657 GOTTLICHER M; WIDMARK E; LI Q; GUSTAFSSON JA FATTY-ACIDS ACTIVATE A CHIMERA OF THE CLOFIBRIC ACID-ACTIVATED RECEPTOR AND THE GLUCOCORTICOID RECEPTOR	515	29
862	16	8632 1993 FEBS LETTERS 332(1-2):1-8 DEGTYARENKO KN; ARCHAKOV AI MOLECULAR EVOLUTION OF P450 SUPERFAMILY AND P450-CONTAINING MONOOXYGENASE SYSTEMS	42	29
863	14	9178 1994 JOURNAL OF BIOCHEMISTRY 116(1):114-120 KOMORI M; ODA Y A MAJOR GLUCOCORTICOID-INDUCIBLE P450 IN RAT-LIVER IS NOT P450 3A1	57	29
864	24	9184 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(5):3387-3396 RIFKIND AB; KANETOSHI A; ORLINICK J; CAPDEVILA JH; LEE C PURIFICATION AND BIOCHEMICAL-CHARACTERIZATION OF 2 MAJOR CYTOCHROME-P-450 ISOFORMS INDUCED BY 2,3,7,8- TETRACHLORODIBENZO-P-DIOXIN IN CHICK-EMBRYO LIVER	56	29
865	25	10450 1996 XENOBIOTICA 26(10):1067-1086 Lewis DFV; Eddershaw PJ; Goldfarb PS; Tarbit MH Molecular modelling of CYP3A4 from an alignment with CYP102: Identification of key interactions between putative active site residues and CYP3A-specific chemicals	49	29
866	6	181 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(5):1686-& KING TE; HOWARD RL PREPARATION AND SOME PROPERTIES OF A REDUCED DIPHOSPPHOPYRIDINE NUCLEOTIDE DEHYDROGENASE FROM SNAKE VENOM DIGEST OF A HEART MUSCLE PREPARATION	86	28
867	5	274 1964 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 108(1):36-& HOMMES FA OSCILLATORY REDUCTIONS OF PYRIDINE NUCLEOTIDES DURING ANAEROBIC GLYCOLYSIS IN BREWERS YEAST	61	28
868	3	563 1966 PHYSIOLOGICAL REVIEWS 46(2):323-& DEDUVE C; BAUDHUIN P PEROXISOMES (MICROBODIES AND RELATED PARTICLES)	1096	28
869	2	623 1967 BIOCHEMICAL PHARMACOLOGY 16(5):871-& KATO R EFFECTS OF STARVATION AND REFEEDING ON OXIDATION OF DRUGS BY LIVER MICROSOMES	86	28
870	5	1030 1969 BIOCHIMICA ET BIOPHYSICA ACTA 176(4):704-& ICHIHARA K; KUSUNOSE E; KUSUNOSE M SOME PROPERTIES AND DISTRIBUTION OF OMEGA-HYDROXYLATION SYSTEM OF MEDIUM-CHAIN FATTY ACIDS	80	28
871	7	1070 1969 EUROPEAN JOURNAL OF BIOCHEMISTRY 10(3):459-& THURMAN RG; SCHOLZ R MIXED FUNCTION OXIDATION IN PERFUSED RAT LIVER - EFFECT OF AMINOPYRINE ON OXYGEN UPTAKE	98	28
872	12	1170 1969 SCIENCE 163(3873):1297-& SIH CJ ENZYMATIC MECHANISM OF STEROID HYDROXYLATION	46	28
873	6	1474 1971 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 45(5):1300-& TSAI RL; GUNSALUS IC; DUS K COMPOSITION AND STRUCTURE OF CAMPHOR HYDROXYLASE COMPONENTS AND HOMOLOGY BETWEEN PUTIDAREDOXIN AND ADRENODOXIN	58	28
874	9	1569 1971 CHEMICO-BIOLOGICAL INTERACTIONS 4(1):75-& GUNSALUS IC; TYSON CA; TSAI R; LIPSCOMB JD P-450CAM HYDROXYLASE - SUBSTRATE-EFFECTOR AND ELECTRON- TRANSPORT REACTIONS	42	28
875	7	1671 1971 MOLECULAR PHARMACOLOGY 7(1):26-& LEIBMAN KC EFFECTS OF EXTRACTION WITH ISOOCTANE UPON PROPERTIES OF LIVER MICROSOMES	43	28
876	15	1885 1972 EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 5(2):116-136 REMMER H INDUCTION OF DRUG-METABOLIZING ENZYME-SYSTEM IN LIVER	226	28
877	12	1937 1972 JOURNAL OF BIOLOGICAL CHEMISTRY 247(19):6103-& SCHLEYER H; ROSENTHA.O; COOPER DY PREPARATION OF HEME PROTEIN P-450 FROM ADRENAL-CORTEX AND SOME OF ITS PROPERTIES	43	28
878	11	2073 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 159(1):39-49 PURVIS JL; CANICK JA; LATIF SA; ROSENBAU.JH; HOLOGGIT.J; MENARD RH LIFETIME OF MICROSOMAL CYTOCHROME-P-450 AND STEROIDOGENIC ENZYMES IN RAT TESTIS AS INFLUENCED BY HUMAN CHORIONIC GONADOTROPIN	105	28
879	10	2502 1974 DRUG METABOLISM AND DISPOSITION 2(4):386-390 BUENING MK; FRANKLIN MR FORMATION OF COMPLEXES ABSORBING AT 455-NM FROM CYTOCHROME-P- 450 AND METABOLITES OF COMPOUNDS RELATED TO SKF 525-A	36	28
880	9	3131 1976 JOURNAL OF BIOLOGICAL CHEMISTRY 251(14):4299-4306 LAMBETH JD; KAMIN H ADRENODOXIN REDUCTASE - PROPERTIES OF COMPLEXES OF REDUCED ENZYME WITH NADP+ AND NADPH	74	28
881	29	3624 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(4):1048-1058 KUMAKI K; SATO M; KON H; NEBERT DW CORRELATION OF TYPE-I, TYPE-II, AND REVERSE TYPE-I DIFFERENCE SPECTRA WITH ABSOLUTE CHANGES IN SPIN STATE OF HEPATIC MICROSOMAL CYTOCHROME-P-450 IRON FROM 5 MAMMALIAN-SPECIES	46	28
882	14	4136 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(7):3057-3061 HANUKOGLU I; JEFCOATE CR MITOCHONDRIAL CYTOCHROME-P-450SCC - MECHANISM OF ELECTRON- TRANSPORT BY ADRENODOXIN	91	28
883	4	4327 1981 CANCER RESEARCH 41(1):120-124 GARRO AJ; SEITZ HK; LIEBER CS ENHANCEMENT OF DIMETHYLNITROSAMINE METABOLISM AND ACTIVATION TO A MUTAGEN FOLLOWING CHRONIC ETHANOL-CONSUMPTION	167	28
884	10	4387 1981 JOURNAL OF BIOLOGICAL CHEMISTRY 256(23):2127-2133 BLAKE RC; COON MJ ON THE MECHANISM OF ACTION OF CYTOCHROME-P-450 - EVALUATION OF HOMOLYTIC AND HETEROLYTIC MECHANISMS OF OXYGEN-OXYGEN BOND- CLEAVAGE DURING SUBSTRATE HYDROXYLATION BY PEROXIDES	76	28
885	15	4649 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(8):4375-4380 BOSTERLING B; TRUDELL JR; TREVOR AJ; BENDIX M LIPID-PROTEIN INTERACTIONS AS DETERMINANTS OF ACTIVATION OR INHIBITION BY CYTOCHROME-B5 OF CYTOCHROME P-450-MEDIATED OXIDATIONS	42	28
886	11	5164 1984 JOURNAL OF BIOLOGICAL CHEMISTRY 259(3):1655-1660 YOSHIDA Y; AOYAMA Y YEAST CYTOCHROME-P-450 CATALYZING LANOSTEROL 14-ALPHA- DEMETHYLATION .1. PURIFICATION AND SPECTRAL PROPERTIES	130	28
887	9	5405 1985 HYPERTENSION 7(6):899-904 ABRAHAM NG; PINTO A; MULLANE KM; LEVERE RD; SPOKAS E PRESENCE OF CYTOCHROME-P-450-DEPENDENT MONOOXYGENASE IN INTIMAL CELLS OF THE HOG AORTA	86	28
888	9	5691 1986 JOURNAL OF BIOLOGICAL CHEMISTRY 261(18):8429-8433 YANAGIBASHI K; HALL PF ROLE OF ELECTRON-TRANSPORT IN THE REGULATION OF THE LYASE ACTIVITY OF C-21 SIDE-CHAIN CLEAVAGE P-450 FROM PORCINE ADRENAL AND TESTICULAR MICROSOMES	74	28
889	6	6106 1988 BIOCHEMISTRY 27(1):80-88 IMAI Y; KOMORI M; SATO R COMPARISON OF PRIMARY STRUCTURES DEDUCED FROM CDNA NUCLEOTIDE- SEQUENCES FOR VARIOUS FORMS OF LIVER MICROSOMAL CYTOCHROME-P- 450 FROM PHENOBARBITAL-TREATED RABBITS	38	28
890	5	6109 1988 BIOCHEMISTRY 27(5):1597-1603 WOLF CR; MILES JS; SEILMAN S; BURKE MD; ROSPENDOWSKI BN; KELLY K; SMITH WE EVIDENCE THAT THE CATALYTIC DIFFERENCES OF 2 STRUCTURALLY HOMOLOGOUS FORMS OF CYTOCHROME-P-450 RELATE TO THEIR HEME ENVIRONMENT	52	28
891	6	6175 1988 DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY 7(4):253-260 LABBE D; JEAN A; ANDERSON A A CONSTITUTIVE MEMBER OF THE RAT CYTOCHROME-P450IIB SUBFAMILY - FULL-LENGTH CODING SEQUENCE OF THE P450IIB3 CDNA	38	28
892	8	6563 1989 DRUG METABOLISM REVIEWS 20(2-4):395-439 LEBLANC GA; WAXMAN DJ INTERACTION OF ANTICANCER DRUGS WITH HEPATIC MONOOXYGENASE ENZYMES	55	28
893	18	6635 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(11):6252-6259 BACKES WL; EYER CS CYTOCHROME-P-450 LM2 REDUCTION - SUBSTRATE EFFECTS ON THE RATE OF REDUCTASE-LM2 ASSOCIATION	42	28
894	5	6700 1989 MOLECULAR CARCINOGENESIS 1(4):253-259 AOYAMA T; GONZALEZ FJ; GELBOIN HV MUTAGEN ACTIVATION BY CDNA-EXPRESSED P1450, P3450, AND P450A	76	28
895	8	6890 1990 BIOCHEMICAL PHARMACOLOGY 40(6):1255-1261 NAKAJIMA T; ELOVAARA E; PARK SS; GELBOIN HV; HIETANEN E; VAINIO H MONOCLONAL ANTIBODY-DIRECTED CHARACTERIZATION OF BENZENE, ETHOXYRESORUFIN AND PENTOXYRESORUFIN METABOLISM IN RAT-LIVER MICROSOMES	70	28
896	16	7155 1990 JOURNAL OF CELLULAR PHYSIOLOGY 144(3):429-437 HARRIS RC; HOMMA T; JACOBSON HR; CAPDEVILA J EPOXYEICOSATRIENOIC ACIDS ACTIVATE NA+/H+ EXCHANGE AND ARE MITOGENIC IN CULTURED RAT GLOMERULAR MESANGIAL CELLS	67	28
897	13	7203 1990 KIDNEY INTERNATIONAL 37(1):94-99 SCHWARTZMAN ML; MARTASEK P; RIOS AR; LEVERE RD; SOLANGI K; GOODMAN AI; ABRAHAM NG CYTOCHROME-P450-DEPENDENT ARACHIDONIC-ACID METABOLISM IN HUMAN- KIDNEY	53	28
898	7	7264 1990 PHARMACOLOGY & THERAPEUTICS 46(2):297-308 MEYER UA; SKODA RC; ZANGER UM THE GENETIC-POLYMORPHISM OF DEBRISOQUINE SPARTEINE METABOLISM MOLECULAR MECHANISMS	81	28
899	9	7370 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 290(2):355-361 WANG RW; KARI PH; LU AYH; THOMAS PE; GUENGERICH FP; VYAS KP BIOTRANSFORMATION OF LOVASTATIN .4. IDENTIFICATION OF CYTOCHROME-P450 3A-PROTEINS AS THE MAJOR ENZYMES RESPONSIBLE FOR THE OXIDATIVE-METABOLISM OF LOVASTATIN IN RAT AND HUMAN LIVER-MICROSOMES	115	28
900	15	7568 1991 EUROPEAN JOURNAL OF CELL BIOLOGY 55(2):336-345 SCHUNCK WH; VOGEL F; GROSS B; KARGEL E; MAUERSBERGER S; KOPKE K; GENGNAGEL C; MULLER HG COMPARISON OF 2 CYTOCHROMES-P-450 FROM CANDIDA-MALTOSA - PRIMARY STRUCTURES, SUBSTRATE SPECIFICITIES AND EFFECTS OF THEIR EXPRESSION IN SACCHAROMYCES-CEREVISIAE ON THE PROLIFERATION OF THE ENDOPLASMIC-RETICULUM	60	28

#	Cited nodes	Nodes / Authors	GCS	LCS
901	11	7579 1991 FISH PHYSIOLOGY AND BIOCHEMISTRY 9(1):1-13 GOKSOYR A; ANDERSSON T; BUHLER DR; STEGEMAN JJ; WILLIAMS DE; FORLIN L IMMUNOCHEMICAL CROSS-REACTIVITY OF BETA-NAPHTHOFLAVONE- INDUCIBLE CYTOCHROME P450 (P450IA) IN LIVER-MICROSOMES FROM DIFFERENT FISH SPECIES AND RAT	80	28
902	11	7632 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(24):15992-15998 LIN D; HARIKRISHNA JA; MOORE CCD; JONES KL; MILLER WL MISSENSE MUTATION SERINE-106 -] PROLINE CAUSES 17-ALPHA- HYDROXYLASE DEFICIENCY	81	28
903	16	7637 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(29):19258-19264 SWANSON BA; DUTTON DR; LUNETTA JM; YANG CS; DEMONTELLANO PRO THE ACTIVE-SITES OF CYTOCHROME-P450 IA1, IIB1, IIB2, AND IIE1 - TOPOLOGICAL ANALYSIS BY INSITU REARRANGEMENT OF PHENYL-IRON COMPLEXES	55	28
904	17	8404 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 304(1):272-278 SAGARA Y; BARNES HJ; WATERMAN MR EXPRESSION IN ESCHERICHIA-COLI OF FUNCTIONAL CYTOCHROME-P450C17 LACKING ITS HYDROPHOBIC AMINO-TERMINAL SIGNAL ANCHOR	44	28
905	10	8498 1993 BIOCHEMISTRY 32(43):11530-11538 LOIDA PJ; SLIGAR SG MOLECULAR RECOGNITION IN CYTOCHROME-P-450 - MECHANISM FOR THE CONTROL OF UNCOUPLING REACTIONS	74	28
906	24	9050 1994 CHEMICAL RESEARCH IN TOXICOLOGY 7(6):836-842 CLARKE SE; BALDWIN SJ; BLOOMER JC; AYRTON AD; SOZIO RS; CHENERY RJ LAURIC ACID AS A MODEL SUBSTRATE FOR THE SIMULTANEOUS DETERMINATION OF CYTOCHROME-P450 2E1 AND 4A IN HEPATIC MICROSOMES	45	28
907	11	9055 1994 CLINICAL PHARMACOKINETICS 26(1):59-70 GONZALEZ FJ; IDLE JR PHARMACOGENETIC PHENOTYPING AND GENOTYPING - PRESENT STATUS AND FUTURE POTENTIAL	143	28
908	13	9186 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(9):6949-6954 QUATTROCHI LC; VU T; TUKEY RH THE HUMAN CYP1A2 GENE AND INDUCTION BY 3-METHYLCHOLANTHRENE - A REGION OF DNA THAT SUPPORTS AH-RECEPTOR BINDING AND PROMOTER- SPECIFIC INDUCTION	97	28
909	25	9248 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 269(1):384-392 CURIPEDROSA R; DAUJAT M; PICHARD L; OURLIN JC; CLAIR P; GERVOT L; LESCA P; DOMERGUE J; JOYEUX H; FOURTANIER G; MAUREL P OMEPRAZOLE AND LANSOPRAZOLE ARE MIXED INDUCERS OF CYP1A AND CYP3A IN HUMAN HEPATOCYTES IN PRIMARY CULTURE	91	28
910	22	9452 1995 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 322(1):76-86 ZELDIN DC; DUBOIS RN; FALCK JR; CAPDEVILA JH MOLECULAR-CLONING, EXPRESSION AND CHARACTERIZATION OF AN ENDOGENOUS HUMAN CYTOCHROME-P450 ARACHIDONIC-ACID EPOXYGENASE ISOFORM	47	28
911	36	9842 1995 PHARMACOGENETICS 5(5):259-274 EATON DL; GALLAGHER EP; BAMMLER TK; KUNZE KL ROLE OF CYTOCHROME P4501A2 IN CHEMICAL CARCINOGENESIS - IMPLICATIONS FOR HUMAN VARIABILITY IN EXPRESSION AND ENZYME- ACTIVITY	91	28
912	23	10193 1996 FASEB JOURNAL 10(2):206-214 GrahamLorence S; Peterson JA P450s: Structural similarities and functional differences	56	28
913	1	106 1960 JOURNAL OF BIOLOGICAL CHEMISTRY 235(2):535-537 PACKER L; ESTABROOK RW; SINGER TP; KIMURA T STUDIES ON CHOLINE DEHYDROGENASE .2. COMPONENTS OF THE CHOLINE OXIDASE SYSTEM AND THE SITE OF ACTION OF AMYTAL	27	27
914	4	182 1962 JOURNAL OF BIOLOGICAL CHEMISTRY 237(7):2384-& PUMPHREY AM STUDIES ON ELECTRON TRANSFER SYSTEM .45. SOME EFFECTS OF ANTIMYCIN ON CYTOCHROME B	75	27
915	2	593 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 121(3):742-& ICHIKAWA Y; YAMANO T ELECTRON SPIN RESONANCE OF MICROSOMAL CYTOCHROMES - CORRELATION OF AMOUNT OF CO-BINDING SPECIES WITH SO-CALLED MICROSOMAL FEX IN MICROSOMES OF NORMAL TISSUES AND LIVER MICROSOMES OF SUDAN 3-TREATED ANIMALS	54	27
916	10	754 1968 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 123(3):484-& OLDHAM SB; WILSON LD; LANDGRAF WL; HARDING BW STUDIES ON ADRENAL CORTICAL CYTOCHROME P-450 .I. EFFECTS OF SUBSTRATES AND ELECTRON DONORS ON ITS CATALYTIC SPECTRAL AND ELECTRON PARAMAGNETIC RESONANCE PROPERTIES	30	27
917	2	1080 1969 FEBS LETTERS 4(2):99-& DIEHL H; CAPALNA S; ULLRICH V PHOTOCHEMICAL ACTION SPECTRUM OF CARBON MONOXIDE INHIBITED HYDROXYLATION OF CYCLOHEXANE BY RAT LIVER MICROSOMES	30	27
918	11	1248 1970 BIOCHEMISTRY 9(7):1615-& WILSON LD STUDIES ON ADRENAL CORTICAL CYTOCHROME P-450 .3. EFFECTS OF CARBON-MONOXIDE AND LIGHT ON STEROID 11BETA HYDROXYLATION	38	27
919	21	1344 1970 JOURNAL OF BIOLOGICAL CHEMISTRY 245(3):519-& NEBERT DW MICROSOMAL CYTOCHROMES B5 AND P450 DURING INDUCTION OF ARYL HYDROCARBON HYDROXYLASE ACTIVITY IN MAMMALIAN CELL CULTURE	54	27
920	3	1430 1971 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 191(DEC31):61-& BURSTEIN S; KUPFER D HYDROXYLATION OF TRANS-DELTA-1-TETRAHYDROCANNABINOL BY HEPATIC MICROSOMAL OXYGENASE	85	27
921	21	1446 1971 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 144(1):143-& IMAI Y; SIEKEVIT.P COMPARISON OF SOME PROPERTIES OF MICROSOMAL CYTOCHROME P-450 FROM NORMAL, METHYLCHOLANTHRENE-TREATED, AND PHENOBARBITAL- TREATED RATS	49	27
922	25	2064 1973 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 157(1):7-22 HRYCAY EG; OBRIEN PJ MICROSOMAL ELECTRON-TRANSPORT .1. REDUCED NICOTINAMIDE ADENINE- DINUCLEOTIDE PHOSPHATE-CYTOCHROME-C REDUCTASE AND CYTOCHROME-P- 450 AS ELECTRON CARRIERS IN MICROSOMAL NADPH-PEROXIDASE ACTIVITY	68	27
923	4	2230 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 37(3):406-414 POMMIER J; DEME D; NUNEZ J EFFECT OF IODIDE CONCENTRATION ON THYROXINE SYNTHESIS CATALYZED BY THYROID PEROXIDASE	94	27
924	22	2281 1973 JOURNAL OF BIOLOGICAL CHEMISTRY 248(6):2192-2201 FUJITA T; SHOEMAN DW; MANNERIN.GJ DIFFERENCES IN P-450 CYTOCHROMES FROM LIVERS OF RATS TREATED WITH PHENOBARBITAL AND WITH 3-METHYLCHOLANTHRENE	60	27
925	45	2603 1974 PHARMACOLOGICAL REVIEWS 26(3):171-197 CAMPBELL TC; HAYES JR ROLE OF NUTRITION IN DRUG-METABOLIZING ENZYME-SYSTEM	300	27
926	9	2609 1974 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 71(4):1441-1445 SHIKITA M; HALL PF STOICHIOMETRY OF CONVERSION OF CHOLESTEROL AND HYDROXYCHOLESTEROLS TO PREGNENOLONE (3BETA-HYDROXYPREGN-5EN-20- ONE) CATALYZED BY ADRENAL CYTOCHROME-P-450	87	27
927	8	2967 1976 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 176(1):91-102 BISSELL DM; HAMMAKER LE CYTOCHROME-P-450 HEME AND REGULATION OF HEPATIC HEME OXYGENASE ACTIVITY	182	27
928	17	3171 1976 MOLECULAR PHARMACOLOGY 12(3):483-493 PHILPOT RM; ARINC E SEPARATION AND PURIFICATION OF 2 FORMS OF HEPATIC CYTOCHROME-P- 450 FROM UNTREATED RABBITS	69	27
929	14	3394 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(9):2908-2917 LAMBETH JD; KAMIN H ADRENODOXIN REDUCTASE AND ADRENODOXIN - MECHANISMS OF REDUCTION OF FERRICYANIDE AND CYTOCHROME-C	61	27
930	12	4001 1980 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 205(2):543-553 GRIFFIN BW; MARTH C; YASUKOCHI Y; MASTERS BSS RADICAL MECHANISM OF AMINOPYRINE OXIDATION BY CUMENE HYDROPEROXIDE CATALYZED BY PURIFIED LIVER MICROSOMAL CYTOCHROME-P-450	70	27
931	20	5068 1984 BIOCHEMISTRY 23(20):4526-4533 TAMBURINI PP; GIBSON GG; BACKES WL; SLIGAR SG; SCHENKMAN JB REDUCTION KINETICS OF PURIFIED RAT-LIVER CYTOCHROME-P-450 - EVIDENCE FOR A SEQUENTIAL REACTION-MECHANISM DEPENDENT ON THE HEMOPROTEIN SPIN STATE	40	27
932	25	5252 1984 XENOBIOTICA 14(1-2):119-137 IOANNIDES C; LUM PY; PARKE DV CYTOCHROME-P-448 AND THE ACTIVATION OF TOXIC-CHEMICALS AND CARCINOGENS	106	27
933	11	5369 1985 DRUG METABOLISM AND DISPOSITION 13(2):156-162 MEREDITH CG; MALDONADO AL; SPEEG KV THE EFFECT OF KETOCONAZOLE ON HEPATIC OXIDATIVE DRUG-METABOLISM IN THE RAT INVIVO AND INVITRO	104	27
934	47	5590 1986 BIOCHIMICA ET BIOPHYSICA ACTA 853(1):1-27 ASTROM A; DEPIERRE JW RAT-LIVER MICROSOMAL CYTOCHROME-P-450 - PURIFICATION, CHARACTERIZATION, MULTIPLICITY AND INDUCTION	60	27
935	5	5724 1986 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 83(24):9443-9447 VONBODMAN SB; SCHULER MA; JOLLIE DR; SLIGAR SG SYNTHESIS, BACTERIAL EXPRESSION, AND MUTAGENESIS OF THE GENE CODING FOR MAMMALIAN CYTOCHROME-B5	135	27
936	12	6031 1988 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 261(2):418-429 NADLER SG; STROBEL HW ROLE OF ELECTROSTATIC INTERACTIONS IN THE REACTION OF NADPH- CYTOCHROME P-450 REDUCTASE WITH CYTOCHROMES P-450	59	27
937	9	6353 1989 ANALYTICAL BIOCHEMISTRY 182(2):300-303 HAMMONDS TD; BLAIR IA; FALCK JR; CAPDEVILA JH RESOLUTION OF EPOXYEICOSATRIENOATE ENANTIOMERS BY CHIRAL PHASE CHROMATOGRAPHY	43	27
938	16	6633 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(8):4442-4449 BROWN CA; BLACK SD MEMBRANE TOPOLOGY OF MAMMALIAN CYTOCHROMES-P-450 FROM LIVER ENDOPLASMIC-RETICULUM - DETERMINATION BY TRYPSINOLYSIS OF PHENOBARBITAL-TREATED MICROSOMES	62	27
939	8	6731 1989 NUCLEIC ACIDS RESEARCH 17(8):2907-2917 MILES JS; BICKMORE W; BROOK JD; MCLAREN AW; MEEHAN R; WOLF CR CLOSE LINKAGE OF THE HUMAN CYTOCHROME-P450IIA AND CYTOCHROME- P450IIB GENE SUBFAMILIES - IMPLICATIONS FOR THE ASSIGNMENT OF SUBSTRATE-SPECIFICITY	46	27
940	12	7228 1990 MOLECULAR ENDOCRINOLOGY 4(3):447-454 WAXMAN DJ; RAM PA; NOTANI G; LEBLANC GA; ALBERTA JA; MORRISSEY JJ; SUNDSETH SS PITUITARY REGULATION OF THE MALE-SPECIFIC STEROID 6-BETA- HYDROXYLASE P-450 2A (GENE-PRODUCT IIIA2) IN ADULT-RAT LIVER - SUPPRESSIVE INFLUENCE OF GROWTH-HORMONE AND THYROXINE ACTING AT A PRETRANSLATIONAL LEVEL	74	27
941	7	7245 1990 MOLECULAR PHARMACOLOGY 38(4):462-470 OMIECINSKI CJ; HASSETT C; COSTA P DEVELOPMENTAL EXPRESSION AND INSITU LOCALIZATION OF THE PHENOBARBITAL-INDUCIBLE RAT HEPATIC MESSENGER-RNAS FOR CYTOCHROME-CYP2B1, CYTOCHROME-CYP2B2, CYTOCHROME-CYP2C6, AND CYTOCHROME-CYP3A1	64	27
942	9	7417 1991 BIOCHEMICAL PHARMACOLOGY 42(2):381-390 WORTELBOER HM; DEKRUIF CA; VANIERSEL AAJ; FALKE HE; NOORDHOEK J; BLAAUBOER BJ COMPARISON OF CYTOCHROME P450 ISOENZYME PROFILES IN RAT-LIVER AND HEPATOCYTE CULTURES - THE EFFECTS OF MODEL INDUCERS ON APOPROTEINS AND BIOTRANSFORMATION ACTIVITIES	103	27
943	13	7626 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(16):10632-10637 KIZAWA H; TOMURA D; ODA M; FUKAMIZU A; HOSHINO T; GOTOH O; YASUI T; SHOUN H NUCLEOTIDE-SEQUENCE OF THE UNIQUE NITRATE NITRITE-INDUCIBLE CYTOCHROME-P-450 CDNA FROM FUSARIUM-OXYSPORUM	66	27
944	12	7766 1991 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 88(20):9141-9145 LARSON JR; COON MJ; PORTER TD PURIFICATION AND PROPERTIES OF A SHORTENED FORM OF CYTOCHROME- P-450 2E1 - DELETION OF THE NH2-TERMINAL MEMBRANE-INSERTION SIGNAL PEPTIDE DOES NOT ALTER THE CATALYTIC ACTIVITIES	45	27
945	26	7928 1992 BIOCHEMICAL PHARMACOLOGY 44(9):1745-1756 KERLAN V; DREANO Y; BERCOVICI JP; BEAUNE PH; FLOCH HH; BERTHOU F NATURE OF CYTOCHROMES P450 INVOLVED IN THE 2-/4-HYDROXYLATIONS OF ESTRADIOL IN HUMAN LIVER-MICROSOMES	87	27
946	5	7961 1992 BIOCHIMICA ET BIOPHYSICA ACTA 1130(2):133-138 ITOH S; YANAGIMOTO T; TAGAWA S; HASHIMOTO H; KITAMURA R; NAKAJIMA Y; OKOCHI T; FUJIMOTO S; UCHINO J; KAMATAKI T GENOMIC ORGANIZATION OF HUMAN FETAL SPECIFIC P-450IIIA7 (CYTOCHROME P-450HFLA)-RELATED GENE(S) AND INTERACTION OF TRANSCRIPTIONAL REGULATORY FACTOR WITH ITS DNA ELEMENT IN THE 5' FLANKING REGION	37	27
947	9	8178 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(25):17913-17919 MOROHASHI K; HONDA S; INOMATA Y; HANDA H; OMURA T A COMMON TRANS-ACTING FACTOR, AD4-BINDING PROTEIN, TO THE PROMOTERS OF STEROIDOGENIC P-450S	246	27
948	15	8805 1993 PHARMACOGENETICS 3(6):291-301 YASUMORI T; NAGATA K; YANG SK; CHEN LS; MURAYAMA N; YAMAZOE Y; KATO R CYTOCHROME-P450 MEDIATED METABOLISM OF DIAZEPAM IN HUMAN AND RAT - INVOLVEMENT OF HUMAN CYP2C IN N-DEMETHYLATION IN THE SUBSTRATE CONCENTRATION-DEPENDENT MANNER	69	27
949	64	9594 1995 CRITICAL REVIEWS IN TOXICOLOGY 25(1):25-65 GOEPTAR AR; SCHEERENS H; VERMEULEN NPE OXYGEN AND XENOBIOTIC REDUCTASE ACTIVITIES OF CYTOCHROME-P450	93	27
950	7	9701 1995 INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 25(2):275-283 TOMITA T; SCOTT JG CDNA AND DEDUCTED PROTEIN-SEQUENCE OF CYP6D1 - THE PUTATIVE GENE FOR A CYTOCHROME-P450 RESPONSIBLE FOR PYRETHROID RESISTANCE IN-HOUSE FLY	51	27
951	17	10199 1996 FEBS LETTERS 397(2-3):210-214 Blake JAR; Pritchard M; Ding SH; Smith GCM; Burchell B; Wolf CR; Friedberg T Coexpression of a human P450 (CYP3A4) and P450 reductase generates a highly functional monooxygenase system in Escherichia coli	45	27
952	29	10502 1997 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 342(2):329-337 Yamazaki H; Gillam EMJ; Dong MS; Johnson WW; Guengerich FP; Shimada T Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: Effects of cytochrome P450-P450 and cytochrome P450-b(5) interactions	44	27
953	10	11795 1999 MOLECULAR PHARMACOLOGY 56(6):1329-1339 Goodwin B; Hodgson E; Liddle C The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module	97	27
954	6	11850 1999 SCIENCE 285(5431):1276-1279 Node K; Huo YQ; Ruan XL; Yang BC; Spiecker M; Ley K; Zeldin DC; Liao JK Anti-inflammatory properties of cytochrome P450 epoxygenase- derived eicosanoids	85	27
955	1	13 1957 JOURNAL OF BIOLOGICAL CHEMISTRY 224(2):637-648 ESTABROOK RW; MACKLER B THE LOW TEMPERATURE SPECTRA OF HEMOPROTEINS .2. CYTOCHROMES OF HEART MUSCLE PREPARATIONS	26	26
956	5	130 1961 JOURNAL OF BIOLOGICAL CHEMISTRY 236(5):1544-& CHANCE B INTERACTION OF ENERGY AND ELECTRON TRANSFER REACTIONS IN MITOCHONDRIA .2. GENERAL PROPERTIES OF ADENOSINE TRIPHOSPHATE- LINKED OXIDATION OF CYTOCHROME AND REDUCTION OF PYRIDINE NUCLEOTIDE	115	26
957	0	255 1963 SCIENCE 140(356):379-& CHANCE B; LEE C; ESTABROOK RW ELECTRON TRANSPORT IN OXYSOME	26	26
958	3	533 1966 JOURNAL OF BIOLOGICAL CHEMISTRY 241(6):1429-& SCHATZ G; RACKER E PARTIAL RESOLUTION OF ENZYMES CATALYZING OXIDATIVE PHOSPHORYLATION .7. OXIDATIVE PHOSPHORYLATION IN DIPHOSPHOPYRIDINE NUCLEOTIDE-CYTOCHROME B SEGMENT OF RESPIRATORY CHAIN - ASSAY AND PROPERTIES IN SUBMITOCHONDRIAL PARTICLES	124	26
959	2	587 1967 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 121(1):129-& MAITRA PK; ESTABROOK RW STUDIES OF BAKERS YEAST METABOLISM .2. ROLE OF ADENINE NUCLEOTIDES AND INORGANIC PHOSPHATE IN CONTROL OF RESPIRATION DURING ALCOHOL OXIDATION	26	26
960	20	956 1969 ANNUAL REVIEW OF BIOCHEMISTRY 38():21-& HAYAISHI O ENZYMIC HYDROXYLATION	128	26
961	22	2228 1973 EUROPEAN JOURNAL OF BIOCHEMISTRY 36(2):583-592 DUPPEL W; LEBEAULT JM; COON MJ PROPERTIES OF A YEAST CYTOCHROME P-450-CONTAINING ENZYME-SYSTEM WHICH CATALYZES HYDROXYLATION OF FATTY-ACIDS, ALKANES, AND DRUGS	116	26
962	14	2419 1974 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 60(2):771-778 HRYCAY EG; ESTABROOK RW EFFECT OF EXTRA BOUND CYTOCHROME-B5 ON CYTOCHROME P-450- DEPENDENT ENZYME-ACTIVITIES IN LIVER-MICROSOMES	26	26
963	6	2599 1974 NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 285(4):315-324 MANSUY D; NASTAINCZYK W; ULLRICH V MECHANISM OF HALOTHANE BINDING TO MICROSOMAL CYTOCHROME P450	91	26
964	15	2709 1975 BIOCHEMICAL PHARMACOLOGY 24(19):1771-1776 POWIS G; BOOBIS AR EFFECT OF WASHING HEPATIC MICROSOMAL FRACTION IN SUCROSE SOLUTIONS AND IN SUCROSE SOLUTION CONTAINING EDTA UPON METABOLISM OF FOREIGN COMPOUNDS	30	26
965	13	3058 1976 COORDINATION CHEMISTRY REVIEWS 19(3):187-251 DUNFORD HB; STILLMAN JS FUNCTION AND MECHANISM OF ACTION OF PEROXIDASES	817	26
966	4	3097 1976 FEBS LETTERS 67(2):123-129 PARRY G; PALMER DN; WILLIAMS DJ LIGAND PARTITIONING INTO MEMBRANES - ITS SIGNIFICANCE IN DETERMINING KM AND KS VALUES FOR CYTOCHROME-P-450 AND OTHER MEMBRANE-BOUND RECEPTORS AND ENZYMES	95	26
967	20	3351 1977 EUROPEAN JOURNAL OF BIOCHEMISTRY 76(2):607-615 MANSUY D; GANS P; CHOTTARD JC; BARTOLI JF NITROSOALKANES AS FE(II) LIGANDS IN 455-NM-ABSORBING CYTOCHROME-P-450 COMPLEXES FORMED FROM NITROALKANES IN REDUCING CONDITIONS	81	26
968	19	3396 1977 JOURNAL OF BIOLOGICAL CHEMISTRY 252(11):3637-3645 CHEVION M; PEISACH J; BLUMBERG WE IMIDAZOLE, LIGAND TRANS TO MERCAPTIDE IN FERRIC CYTOCHROME-P- 450 - EPR STUDY OF PROTEINS AND MODEL COMPOUNDS	118	26
969	28	3431 1977 LIFE SCIENCES 21(8):1047-1057 YANG CS ORGANIZATION AND INTERACTION OF MONOXYGENASE ENZYMES IN MICROSOMAL MEMBRANE	55	26
970	9	3451 1977 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 74(12):5477-5481 SATO R; ATSUTA Y; IMAI Y; TANIGUCHI S; OKUDA K HEPATIC MITOCHONDRIAL CYTOCHROME-P-450 - ISOLATION AND FUNCTIONAL CHARACTERIZATION	78	26
971	15	3632 1978 JOURNAL OF BIOLOGICAL CHEMISTRY 253(14):4924-4929 CHURCHILL PF; DEALVARE LR; KIMURA T TOPOLOGICAL STUDIES OF STEROID HYDROXYLASE COMPLEXES IN BOVINE ADRENOCORTICAL MITOCHONDRIA	69	26
972	6	4039 1980 BIOCHEMICAL PHARMACOLOGY 29(22):3075-3080 PELKONEN O; PUURUNEN J THE EFFECT OF CIMETIDINE ON INVITRO AND INVIVO MICROSOMAL DRUG- METABOLISM IN THE RAT	181	26
973	9	4139 1980 JOURNAL OF BIOLOGICAL CHEMISTRY 255(9):4020-4027 HORNSBY PJ REGULATION OF CYTOCHROME P-450-SUPPORTED 11 BETA-HYDROXYLATION OF DEOXYCORTISOL BY STEROIDS, OXYGEN, AND ANTIOXIDANTS IN ADRENOCORTICAL CELL-CULTURES	129	26
974	16	4659 1982 JOURNAL OF BIOLOGICAL CHEMISTRY 257(12):7030-7036 GUT J; RICHTER C; CHERRY RJ; WINTERHALTER KH; KAWATO S ROTATION OF CYTOCHROME-P-450 .2. SPECIFIC INTERACTIONS OF CYTOCHROME-P-450 WITH NADPH-CYTOCHROME P-450 REDUCTASE IN PHOSPHOLIPID-VESICLES	61	26
975	23	4921 1983 JOURNAL OF BIOLOGICAL CHEMISTRY 258(15):9398-9405 FUNKENSTEIN B; MCCARTHY JL; DUS KM; SIMPSON ER; WATERMAN MR EFFECT OF ADRENOCORTICOTROPIN ON STEROID 21-HYDROXYLASE SYNTHESIS AND ACTIVITY IN CULTURED BOVINE ADRENOCORTICAL-CELLS - INCREASED SYNTHESIS IN THE ABSENCE OF INCREASED ACTIVITY	63	26
976	10	5318 1985 BIOCHEMISTRY 24(23):6591-6597 SHEETS JJ; ESTABROOK RW MULTIPLE SITES OF STEROID HYDROXYLATION BY THE LIVER MICROSOMAL CYTOCHROME-P-450 SYSTEM - PRIMARY AND SECONDARY METABOLISM OF ANDROSTENEDIONE	26	26
977	3	5553 1986 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 136(1):169-176 WOOLLARD PM STEREOCHEMICAL DIFFERENCE BETWEEN 12-HYDROXY-5,8,10,14- EICOSATETRAENOIC ACID IN PLATELETS AND PSORIATIC LESIONS	145	26
978	29	5857 1987 CHEMICAL REVIEWS 87(5):1255-1276 DAWSON JH; SONO M CYTOCHROME.P-450 AND CHLOROPEROXIDASE - THIOLATE-LIGATED HEME ENZYMES - SPECTROSCOPIC DETERMINATION OF THEIR ACTIVE-SITE STRUCTURES AND MECHANISTIC IMPLICATIONS OF THIOLATE LIGATION	268	26
979	9	5925 1987 JOURNAL OF PEDIATRICS 111(1):1-17 MILLER WL; LEVINE LS MOLECULAR AND CLINICAL ADVANCES IN CONGENITAL ADRENAL- HYPERPLASIA	125	26
980	3	6050 1988 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 150(1):304-310 KUBOTA S; LASKER JM; LIEBER CS MOLECULAR REGULATION OF ETHANOL-INDUCIBLE CYTOCHROME-P450-IIEI IN HAMSTERS	68	26
981	1	6093 1988 BIOCHEMICAL PHARMACOLOGY 37(19):3735-3741 EDWARDS RJ; SINGLETON AM; SESARDIC D; BOOBIS AR; DAVIES DS ANTIBODIES TO A SYNTHETIC PEPTIDE THAT REACT SPECIFICALLY WITH A COMMON SURFACE REGION ON 2 HYDROCARBON-INDUCIBLE ISOENZYMES OF CYTOCHROME-P-450 IN THE RAT	47	26
982	2	6260 1988 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 247(1):242-247 OTTON SV; CREWE HK; LENNARD MS; TUCKER GT; WOODS HF USE OF QUINIDINE INHIBITION TO DEFINE THE ROLE OF THE SPARTEINE DEBRISOQUINE CYTOCHROME-P450 IN METOPROLOL OXIDATION BY HUMAN- LIVER MICROSOMES	132	26
983	8	6705 1989 MOLECULAR ENDOCRINOLOGY 3(9):1399-1408 IKEYA K; JAISWAL AK; OWENS RA; JONES JE; NEBERT DW; KIMURA S HUMAN CYP1A2 - SEQUENCE, GENE STRUCTURE, COMPARISON WITH THE MOUSE AND RAT ORTHOLOGOUS GENE, AND DIFFERENCES IN LIVER 1A2 MESSENGER-RNA EXPRESSION	79	26
984	39	6759 1989 RECENT PROGRESS IN HORMONE RESEARCH 45():533-566 WATERMAN MR; SIMPSON ER REGULATION OF STEROID HYDROXYLASE GENE-EXPRESSION IS MULTIFACTORIAL IN NATURE	88	26
985	18	6943 1990 BIOCHIMIE 72(6-7):463-472 URBAN P; CULLIN C; POMPON D MAXIMIZING THE EXPRESSION OF MAMMALIAN CYTOCHROME-P-450 MONOOXYGENASE ACTIVITIES IN YEAST-CELLS	85	26
986	2	7456 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1092(2):233-243 YAMADA J; SAKUMA M; IKEDA T; FUKUDA K; SUGA T CHARACTERISTICS OF DEHYDROEPIANDROSTERONE AS A PEROXISOME PROLIFERATOR	76	26
987	7	7494 1991 CARCINOGENESIS 12(12):2211-2219 ISLAM SA; WOLF CR; LENNARD MS; STERNBERG MJE A 3-DIMENSIONAL MOLECULAR TEMPLATE FOR SUBSTRATES OF HUMAN CYTOCHROME-P450 INVOLVED IN DEBRISOQUINE 4-HYDROXYLATION	73	26
988	3	7651 1991 JOURNAL OF CLINICAL INVESTIGATION 87(5):1664-1667 WHITE PC; DUPONT J; NEW MI; LEIBERMAN E; HOCHBERG Z; ROSLER A A MUTATION IN CYP11B1 (ARG-448-]HIS) ASSOCIATED WITH STEROID 11-BETA-HYDROXYLASE DEFICIENCY IN JEWS OF MOROCCAN ORIGIN	93	26
989	11	7829 1992 AMERICAN JOURNAL OF PHYSIOLOGY 262(1):F8-F16 OMATA K; ABRAHAM NG; ESCALANTE B; SCHWARTZMAN ML AGE-RELATED-CHANGES IN RENAL CYTOCHROME-P-450 ARACHIDONIC-ACID METABOLISM IN SPONTANEOUSLY HYPERTENSIVE RATS	84	26
990	23	7846 1992 AQUATIC TOXICOLOGY 24(1-2):1-19 ANDERSSON T; FORLIN L REGULATION OF THE CYTOCHROME-P450 ENZYME-SYSTEM IN FISH	104	26
991	7	7899 1992 BIOCHEMICAL JOURNAL 285():979-983 HONKAKOSKI P; KOJO A; LANG MA REGULATION OF THE MOUSE-LIVER CYTOCHROME-P450 2B SUBFAMILY BY SEX-HORMONES AND PHENOBARBITAL	52	26
992	14	8161 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(6):3907-3914 SUNDSETH SS; ALBERTA JA; WAXMAN DJ SEX-SPECIFIC, GROWTH HORMONE-REGULATED TRANSCRIPTION OF THE CYTOCHROME-P450 2C11 AND 2C12 GENES	86	26
993	8	8166 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(12):8050-8055 BARKER CW; FAGAN JB; PASCO DS INTERLEUKIN-1-BETA SUPPRESSES THE INDUCTION OF P4501A1 AND P4501A2 MESSENGER-RNAS IN ISOLATED HEPATOCYTES	99	26
994	2	8314 1992 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 89(11):4855-4859 WATERS LC; ZELHOF AC; SHAW BJ; CHANG LY POSSIBLE INVOLVEMENT OF THE LONG TERMINAL REPEAT OF TRANSPOSABLE ELEMENT-17.6 IN REGULATING EXPRESSION OF AN INSECTICIDE RESISTANCE-ASSOCIATED P450-GENE IN DROSOPHILA	65	26
995	22	8562 1993 CHEMICAL RESEARCH IN TOXICOLOGY 6(4):470-479 ROBERTS ES; HOPKINS NE; ALWORTH WL; HOLLENBERG PF MECHANISM-BASED INACTIVATION OF CYTOCHROME-P450 2B1 BY 2- ETHYNYLNAPHTHALENE - IDENTIFICATION OF AN ACTIVE-SITE PEPTIDE	48	26
996	18	8693 1993 JOURNAL OF BIOLOGICAL CHEMISTRY 268(23):17384-17391 BOUCHER PD; RUCH RJ; HINES RN SPECIFIC NUCLEAR-PROTEIN BINDING TO A NEGATIVE REGULATORY ELEMENT ON THE HUMAN CYP1A1 GENE	59	26
997	8	9073 1994 DNA AND CELL BIOLOGY 13(6):663-668 FROLOV MV; ALATORTSEV VE CLUSTER OF CYTOCHROME-P450 GENES ON THE X-CHROMOSOME OF DROSOPHILA-MELANOGASTER	34	26
998	10	9294 1994 MOLECULAR ENDOCRINOLOGY 8(2):210-217 TODA K; SIMPSON ER; MENDELSON CR; SHIZUTA Y; KILGORE MW EXPRESSION OF THE GENE ENCODING AROMATASE CYTOCHROME-P450 (CYP19) IN FETAL TISSUES	75	26
999	40	9394 1994 XENOBIOTICA 24(12):1151-1175 NEDELCHEVA V; GUT I P450 IN THE RAT AND MAN - METHODS OF INVESTIGATION, SUBSTRATE SPECIFICITIES AND RELEVANCE TO CANCER	71	26
1000	31	9571 1995 CHEMICAL RESEARCH IN TOXICOLOGY 8(2):218-225 UENG YF; SHIMADA T; YAMAZAKI H; GUENGERICH FP OXIDATION OF AFLATOXIN B-1 BY BACTERIAL RECOMBINANT HUMAN CYTOCHROME-P450 ENZYMES	104	26

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