#	Cited nodes	Nodes / Authors	GCS	LCS
5601	4	4406 1981 JOURNAL OF NUTRITION 111(2):252-259 TYZBIR RS; KUNIN AS; SIMS NM; DANFORTH E INFLUENCE OF DIET COMPOSITION ON SERUM TRIIODOTHYRONINE (T3) CONCENTRATION, HEPATIC MITOCHONDRIAL METABOLISM AND SHUTTLE SYSTEM ACTIVITY IN RATS	51	3
5602	10	4420 1981 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 103(12):3601-3603 LEDON HJ; DURBUT P; VARESCON F SELECTIVE EPOXIDATION OF OLEFINS BY MOLYBDENUM PORPHYRIN CATALYZED PEROXY-BOND HETEROLYSIS	63	3
5603	15	4434 1981 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 15(1):32-42 CHANG KM; WILKINSON CF; HETNARSKI K SPECTRAL AND INHIBITORY INTERACTIONS OF METHYLENEDIOXYPHENYL COMPOUNDS WITH SOUTHERN ARMYWORM (SPODOPTERA-ERIDANIA) MIDGUT MICROSOMES	10	3
5604	7	4436 1981 PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 16(3):187-198 BRATTSTEN LB; GUNDERSON CA ISOLATION OF INSECT MICROSOMAL OXIDASES BY RAPID CENTRIFUGATION	22	3
5605	38	4468 1981 USPEKHI KHIMII 50(11):2019-2048 METELITSA DI CYTOCHROME-P-450 AS AN EFFECTIVE CATALYST IN OXIDATION OF ORGANIC-COMPOUNDS, USING PEROXIDES	9	3
5606	3	4497 1982 ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 393(SEP):1-22 PRYOR WA FREE-RADICAL BIOLOGY - XENOBIOTICS, CANCER, AND AGING	118	3
5607	9	4502 1982 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 215(2):462-477 GUENGERICH FP; DAVIDSON NK INTERACTION OF EPOXIDE HYDROLASE WITH ITSELF AND OTHER MICROSOMAL PROTEINS	17	3
5608	7	4507 1982 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 217(1):205-215 DAS M; SETH PK; DIXIT R; MUKHTAR H ARYL-HYDROCARBON HYDROXYLASE OF RAT-BRAIN MITOCHONDRIA - PROPERTIES OF, AND EFFECT OF INHIBITORS AND INDUCERS ON, ENZYME-ACTIVITY	21	3
5609	2	4511 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 105(2):546-552 DIXIT R; MUKHTAR H; BICKERS DR EVIDENCE THAT LIPID-PEROXIDATION IN MICROSOMAL-MEMBRANES OF EPIDERMIS IS ASSOCIATED WITH GENERATION OF HYDROGEN-PEROXIDE AND SINGLET OXYGEN	17	3
5610	16	4512 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 106(3):927-932 NOSHIRO M; HAYASHI S; MURAKAMI K; OKUDA K THE INVOLVEMENT OF CYTOCHROME-B5 IN 5-BETA-CHOLESTANE-3-ALPHA, 7-ALPHA, 12-ALPHA-TRIOL 25-HYDROXYLATION AND TAURODEOXYCHOLATE 7-ALPHA-HYDROXYLATION OF RAT-LIVER	10	3
5611	2	4518 1982 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 108(3):1271-1277 CHADHA A; MADYASTHA KM OMEGA-HYDROXYLATION OF ACYCLIC MONOTERPENE ALCOHOLS BY RAT LUNG MICROSOMES	18	3
5612	3	4522 1982 BIOCHEMICAL JOURNAL 202(1):97-105 NARABAYASHI H; TAKESHIGE K; MINAKAMI S ALTERATION OF INNER-MEMBRANE COMPONENTS AND DAMAGE TO ELECTRON- TRANSFER ACTIVITIES OF BOVINE HEART SUB-MITOCHONDRIAL PARTICLES INDUCED BY NADPH-DEPENDENT LIPID-PEROXIDATION	75	3
5613	6	4529 1982 BIOCHEMICAL PHARMACOLOGY 31(2):249-251 MUAKKASSAH SF; BIDLACK WR; YANG WCT REVERSAL OF THE EFFECTS OF ISONIAZID ON HEPATIC CYTOCHROME-P- 450 BY POTASSIUM FERRICYANIDE	6	3
5614	6	4534 1982 BIOCHEMICAL PHARMACOLOGY 31(7):1273-1277 BOCK KW; LILIENBLUM W; PFEIL H FUNCTIONAL-HETEROGENEITY OF UDP-GLUCURONOSYLTRANSFERASE ACTIVITIES IN C57BL/6 AND DBA/2 MICE	37	3
5615	6	4540 1982 BIOCHEMICAL PHARMACOLOGY 31(11):1993-1998 POPOVA VI; LEONOVA IN; WEINER LM; SALGANIK RI INTERACTION OF THE SUBSTRATE-ANALOG OF CYTOCHROME-P-450 AND MIXED-FUNCTION OXIDASES	8	3
5616	5	4547 1982 BIOCHEMICAL PHARMACOLOGY 31(22):3667-3671 TOFILON PJ; PIPER WN INHIBITION OF RAT TESTICULAR HEME-SYNTHESIS AND DEPRESSION OF MICROSOMAL CYTOCHROME-P-450 BY ESTRADIOL BENZOATE	8	3
5617	11	4568 1982 BIOORGANICHESKAYA KHIMIYA 8(5):630-642 USANOV SA; KURCHENKO VP; METELITZA DI COMPARISON OF RECONSTITUTED ENZYME-SYSTEMS FOR RABBIT LIVER- MICROSOMES CONTAINING CYTOCHROME-P-450-LM2 AND CYTOCHROME-P- 450-LM4	13	3
5618	11	4582 1982 CANCER RESEARCH 42(11):4473-4478 MILLER AG; WHITLOCK JP EFFICIENT METABOLISM OF BENZO(A)PYRENE AT NANOMOLAR CONCENTRATIONS BY INTACT MURINE HEPATOMA-CELLS	13	3
5619	10	4592 1982 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 73(2):277-283 FABACHER DL HEPATIC MICROSOMES FROM FRESH-WATER FISH .1. INVITRO CYTOCHROME-P-450 CHEMICAL INTERACTIONS	12	3
5620	15	4598 1982 DRUG METABOLISM REVIEWS 13(1):71-121 LINDEKE B THE NON-ENZYMATIC AND POSTENZYMATIC CHEMISTRY OF N-OXYGENATED MOLECULES	23	3
5621	3	4612 1982 FARMACO-EDIZIONE SCIENTIFICA 37(3):184-191 FACINO RM; CARINI M LOSS OF SUBSTRATE BINDING-CAPACITY OF THE HEPATIC-MICROSOMAL CYTOCHROME-P-450 IN FASCIOLA-HEPATICA INFECTED-RATS - TOXICOLOGICAL IMPLICATIONS	1	3
5622	1	4616 1982 FEBS LETTERS 140(2):245-247 GEERTS A; ROELS F INVIVO COOPERATION BETWEEN HEPATIC CATALASE AND SUPEROXIDE- DISMUTASE DEMONSTRATED BY DIETHYLDITHIOCARBAMATE	23	3
5623	11	4633 1982 JOURNAL OF BIOCHEMISTRY 92(6):1693-1701 NONAKA Y; SUGIYAMA T; YAMANO T ARGINYL RESIDUES OF ADRENODOXIN REDUCTASE AS THE ANION RECOGNITION SITE FOR 2'-PHOSPHATE GROUP OF NADP+	9	3
5624	9	4635 1982 JOURNAL OF BIOCHEMISTRY 92(6):1941-1950 SAKAMOTO H; OHTA M; MIURA R; SUGIYAMA T; YAMANO T; MIYAKE Y STUDIES ON THE REACTION-MECHANISM OF NADPH-ADRENODOXIN REDUCTASE WITH NADPH	4	3
5625	3	4680 1982 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 10(4-5):601-611 DANNERRABOVSKY J; GROSECLOSE RD STABILITY OF RAT LUNG AND LIVER MICROSOMAL CYTOCHROME-P-450 ENZYME-ACTIVITIES TO STORAGE - PURIFIED MICROSOMAL FRACTION, POSTMITOCHONDRIAL FRACTION, AND WHOLE TISSUE	23	3
5626	10	4683 1982 MEDICAL BIOLOGY 60(5):237-254 SUOLINNA EM ISOLATION AND CULTURE OF LIVER-CELLS AND THEIR USE IN THE BIOCHEMICAL-RESEARCH OF XENOBIOTICS	37	3
5627	7	4688 1982 MOLECULAR PHARMACOLOGY 21(2):464-467 SAWAHATA T; NEAL RA INHIBITION OF RAT-LIVER CYTOCHROME-P-450 BY BENZYL HYDRODISULFIDE	9	3
5628	43	4697 1982 PHARMACOLOGY & THERAPEUTICS 16(3):377-429 KLINGER W BIOTRANSFORMATION OF DRUGS AND OTHER XENOBIOTICS DURING POSTNATAL-DEVELOPMENT	58	3
5629	11	4702 1982 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES 79(19):5773-5777 SHEETS JJ; VICKERY LE PROXIMITY OF THE SUBSTRATE BINDING-SITE AND THE HEME-IRON CATALYTIC SITE IN CYTOCHROME P-450SCC	34	3
5630	26	4720 1982 VITAMINS AND HORMONES-ADVANCES IN RESEARCH AND APPLICATIONS 39():175-229 NUNEZ J; POMMIER J FORMATION OF THYROID-HORMONES	89	3
5631	10	4723 1982 XENOBIOTICA 12(5):303-313 SONAWANE BR; YAFFE SJ; WITMER CM EFFECTS OF ENDOTOXIN UPON RAT HEPATIC-MICROSOMAL DRUG- METABOLISM INVIVO AND INVITRO	28	3
5632	7	4772 1983 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 115(3):995-1001 BOSTERLING B; TRUDELL JR EVIDENCE FOR LEUKOTRIENE-A4 AS AN INTERMEDIATE IN THE CONVERSION OF 5-HPETE TO LEUKOTRIENE-B4 CATALYZED BY CYTOCHROME-P-450	12	3
5633	11	4795 1983 BIOCHEMICAL PHARMACOLOGY 32(24):3823-3829 ROSENBERG DW; DRUMMOND GS DIRECT INVITRO EFFECTS OF BIS(TRI-N-BUTYLTIN)OXIDE ON HEPATIC CYTOCHROME-P-450	22	3
5634	5	4812 1983 BIOCHIMICA ET BIOPHYSICA ACTA 752(1):73-78 AUPETIT B; ACCARIE C; EMERIC N; VONARX V; LEGRAND JC THE FINAL STEP OF ALDOSTERONE BIOSYNTHESIS REQUIRES REDUCING POWER IT IS NOT A DEHYDROGENATION	19	3
5635	2	4813 1983 BIOCHIMICA ET BIOPHYSICA ACTA 756(2):191-195 GOVINDWAR SP; KACHOLE MS; PAWAR SS PARTIAL INHIBITION OF HEPATIC-MICROSOMAL AMINOPYRINE N- DEMETHYLASE BY CAFFEINE IN PARTIALLY PURIFIED CYTOCHROME-P-450	10	3
5636	16	4828 1983 CANADIAN JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY 61(7):722-730 SENCIALL IR; BULLOCK G; RAHAL S PROGESTERONE C21 HYDROXYLATION AND STEROID CARBOXYLIC-ACID BIOSYNTHESIS IN THE RABBIT - INVITRO STUDIES WITH ENDOCRINE, METABOLIC, AND POTENTIAL TARGET TISSUES	17	3
5637	6	4833 1983 CARCINOGENESIS 4(11):1429-1435 BOUX LJ; DUKE CC; HOLDER GM; IRELAND CM; RYAN AJ METABOLISM OF 7-METHYLBENZ[C]ACRIDINE - COMPARISON OF RAT-LIVER AND LUNG MICROSOMAL PREPARATIONS AND IDENTIFICATION OF SOME MINOR METABOLITES	24	3
5638	1	4842 1983 CHEMICO-BIOLOGICAL INTERACTIONS 47(1):111-122 ROGAN EG; HAKAM A; CAVALIERI EL STRUCTURE ELUCIDATION OF A 6-METHYLBENZO[A]PYRENE-DNA ADDUCT FORMED BY HORSERADISH-PEROXIDASE INVITRO AND MOUSE SKIN INVIVO	15	3
5639	2	4852 1983 DRUG METABOLISM AND DISPOSITION 11(6):550-555 COOMES MW; PROUGH RA THE MITOCHONDRIAL METABOLISM OF 1,2-DISUBSTITUTED HYDRAZINES, PROCARBAZINE AND 1,2-DIMETHYLHYDRAZINE	21	3
5640	25	4854 1983 DRUG METABOLISM REVIEWS 14(4):741-799 MCLANE KE; FISHER J; RAMAKRISHNAN K REDUCTIVE DRUG-METABOLISM	40	3
5641	15	4862 1983 EUROPEAN JOURNAL OF BIOCHEMISTRY 134(1):89-95 ARCHAKOV AI; BORODIN EA; DOBRETSOV GE; KARASEVICH EI; KARYAKIN AV THE INFLUENCE OF CHOLESTEROL INCORPORATION AND REMOVAL ON LIPID-BILAYER VISCOSITY AND ELECTRON-TRANSFER IN RAT-LIVER MICROSOMES	13	3
5642	3	4865 1983 EUROPEAN JOURNAL OF BIOCHEMISTRY 135(1):89-94 KUHN W; GOTTSCHALK G CHARACTERIZATION OF THE CYTOCHROMES OCCURRING IN METHANOSARCINA SPECIES	42	3
5643	2	4872 1983 FEMS MICROBIOLOGY LETTERS 20(3):407-410 KUHN W; FIEBIG K; HIPPE H; MAH RA; HUSER BA; GOTTSCHALK G DISTRIBUTION OF CYTOCHROMES IN METHANOGENIC BACTERIA	56	3
5644	5	4897 1983 JOURNAL OF BIOCHEMISTRY 94(4):1301-1306 KANG DC; NARABAYASHI H; SATA T; TAKESHIGE K KINETICS OF SUPEROXIDE FORMATION BY RESPIRATORY-CHAIN NADH- DEHYDROGENASE OF BOVINE HEART-MITOCHONDRIA	20	3
5645	14	4898 1983 JOURNAL OF BIOCHEMISTRY 94(5):1505-1515 NABI N; ISHIKAWA T; OHASHI M; OMURA T CONTRIBUTIONS OF CYTOPLASMIC FREE AND MEMBRANE-BOUND RIBOSOMES TO THE SYNTHESIS OF NADPH-ADRENODOXIN REDUCTASE AND ADRENODOXIN OF BOVINE ADRENAL-CORTEX MITOCHONDRIA	14	3
5646	1	4926 1983 JOURNAL OF INVESTIGATIVE DERMATOLOGY 81(6):566-571 BEDORD CJ; YOUNG JM; WAGNER BM ANTHRALIN INHIBITION OF MOUSE EPIDERMAL ARACHIDONIC-ACID LIPOXYGENASE INVITRO	44	3
5647	17	4928 1983 JOURNAL OF MEDICINAL CHEMISTRY 26(10):1343-1348 DUQUETTE PH; ERICKSON RR; HOLTZMAN JL ROLE OF SUBSTRATE LIPOPHILICITY ON THE N-DEMETHYLATION AND TYPE-I BINDING OF 3-O-ALKYLMORPHINE ANALOGS	6	3
5648	4	4931 1983 JOURNAL OF NEUROCHEMISTRY 41(5):1370-1383 FITZPATRICK SM; COOPER AJL; DUFFY TE USE OF BETA-METHYLENE-D,L-ASPARTATE TO ASSESS THE ROLE OF ASPARTATE-AMINOTRANSFERASE IN CEREBRAL OXIDATIVE-METABOLISM	83	3
5649	9	4970 1983 MOLECULAR PHARMACOLOGY 23(3):748-757 JEFFERY EH; MANNERING GJ INTERACTION OF CONSTITUTIVE AND PHENOBARBITAL-INDUCED CYTOCHROME-P-450 ISOZYMES DURING THE SEQUENTIAL OXIDATION OF BENZPHETAMINE - EXPLANATION FOR THE DIFFERENCE IN BENZPHETAMINE-INDUCED HYDROGEN-PEROXIDE PRODUCTION AND 455-NM COMPLEX-FORMATION IN MICROSOMES FROM UNTREATED AND PHENOBARBITAL-TREATED RATS	11	3
5650	5	5023 1984 ANALYTICAL CHEMISTRY 56(11):1849-1852 KEOUGH T; MIHELICH ED; EICKHOFF DJ DIFFERENTIATION OF MONOEPOXIDE ISOMERS OF POLY-UNSATURATED FATTY-ACIDS AND FATTY-ACID ESTERS BY LOW-ENERGY CHARGE-EXCHANGE MASS-SPECTROMETRY	12	3
5651	3	5025 1984 ANNUAL REVIEW OF BIOCHEMISTRY 53():493-535 WALSH CT SUICIDE SUBSTRATES, MECHANISM BASED ENZYME INACTIVATORS - RECENT DEVELOPMENTS	213	3
5652	5	5037 1984 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 235(2):538-543 CUELLAR A; ESCAMILLA E; RAMIREZ J; CHAVEZ E ADRIAMYCIN AS AN INHIBITOR OF 11-BETA-HYDROXYLASE ACTIVITY IN ADRENAL-CORTEX MITOCHONDRIA	5	3
5653	8	5075 1984 BIOCHIMICA ET BIOPHYSICA ACTA 787(2):174-182 VANZYL JM; VANDERWALT BJ SOLUBILIZATION OF PEROXIDASE FROM PORCINE THYROIDS AND CHARACTERIZATION BY PHOTOAFFINITY-LABELING	9	3
5654	8	5095 1984 CHEMICA SCRIPTA 24(4-5):230-235 THORNSTROM PE; SOUSSI B; ARVIDSSON L; MALMSTROM BG EFFECT OF PH, IONIC-STRENGTH AND D2O ON THE STEADY-STATE KINETICS OF CYTOCHROME-C OXIDASE IN PHOSPHOLIPID-VESICLES	39	3
5655	13	5102 1984 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 77(4):761-767 NOSHIRO M; OMURA T MICROSOMAL MONOOXYGENASE SYSTEM IN FROG LIVERS	7	3
5656	12	5107 1984 CRC CRITICAL REVIEWS IN TOXICOLOGY 12(4):315-342 DIGUISEPPI J; FRIDOVICH I THE TOXICOLOGY OF MOLECULAR-OXYGEN	124	3
5657	20	5108 1984 CRC CRITICAL REVIEWS IN TOXICOLOGY 13(2):99-160 RUSH GF; SMITH JH; NEWTON JF; HOOK JB CHEMICALLY-INDUCED NEPHROTOXICITY - ROLE OF METABOLIC- ACTIVATION	77	3
5658	25	5115 1984 DRUG METABOLISM REVIEWS 15(5-6):897-917 WILKINSON CF; MURRAY M CONSIDERATIONS OF TOXICOLOGIC INTERACTIONS IN DEVELOPING NEW CHEMICALS	19	3
5659	4	5143 1984 HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE 365(7):773-779 KUHNVELTEN N; BUNSE T; SCHURER N; STAIB W DIRECT EFFECT OF ANDROGENS ON PROGESTERONE BINDING AND METABOLISM IN RAT TESTIS MICROSOMES	7	3
5660	10	5233 1984 TETRAHEDRON 40(3):553-568 TRAYLOR TG; LEE WA; STYNES DV MODEL-COMPOUND STUDIES RELATED TO PEROXIDASES .2. THE CHEMICAL- REACTIVITY OF A HIGH VALENT PROTOHEMIN COMPOUND	45	3
5661	4	5241 1984 TOXICOLOGY LETTERS 23(1):25-32 WHITE RD; NORTON R; BUS JS THE EFFECT OF BUTHIONINE SULFOXIMINE, AN INHIBITOR OF GLUTATHIONE SYNTHESIS, ON HEPATIC DRUG-METABOLISM IN THE MALE- MOUSE	27	3
5662	8	5244 1984 TRENDS IN BIOCHEMICAL SCIENCES 9(10):446-449 COULSON CJ; KING DJ; WISEMAN A CHEMOTHERAPEUTIC AND AGROCHEMICAL APPLICATIONS OF CYTOCHROME-P- 450 LIGANDS	22	3
5663	1	5264 1985 ANNALS OF EMERGENCY MEDICINE 14(12):1163-1167 MYERS RAM; SNYDER SK; EMHOFF TA SUBACUTE SEQUELAE OF CARBON-MONOXIDE POISONING	74	3
5664	5	5271 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 236(2):585-592 DARDAS A; GAL D; BARRELLE M; SAURETIGNAZI G; STERJIADES R; PELMONT J THE DEMETHYLATION OF GUAIACOL BY A NEW BACTERIAL CYTOCHROME-P- 450	18	3
5665	2	5276 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 238(2):588-595 BORRELLO S; MINOTTI G; PALOMBINI G; GRATTAGLIANO A; GALEOTTI T SUPEROXIDE-DEPENDENT LIPID-PEROXIDATION AND VITAMIN-E CONTENT OF MICROSOMES FROM HEPATOMAS WITH DIFFERENT GROWTH-RATES	27	3
5666	3	5280 1985 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 241(1):149-162 NASHED NT; MICHAUD DP; LEVIN W; JERINA DM PROPERTIES OF LIVER MICROSOMAL CHOLESTEROL 5,6-OXIDE HYDROLASE	20	3
5667	8	5287 1985 ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY 2(4):385-396 WEIRICH GF; SVOBODA JA; THOMPSON MJ ECDYSONE 20-MONOOXYGENASE IN MITOCHONDRIA AND MICROSOMES OF MANDUCA-SEXTA (L) MIDGUT - IS THE DUAL LOCALIZATION REAL	26	3
5668	7	5295 1985 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 133(3):1057-1063 CRESNAR B; BRESKVAR K; HUDNIKPLEVNIK T RESOLUTION AND RECONSTITUTION OF THE NADPH-CYTOCHROME-C (P-450) REDUCTASE INDUCED BY PROGESTERONE IN RHIZOPUS NIGRICANS	13	3
5669	2	5331 1985 BIOCHIMICA ET BIOPHYSICA ACTA 835(2):378-384 HAEGGSTROM J; RADMARK O; FITZPATRICK FA LEUKOTRIENE A4-HYDROLASE ACTIVITY IN GUINEA-PIG AND HUMAN-LIVER	40	3
5670	13	5333 1985 BIOLOGICAL CHEMISTRY HOPPE-SEYLER 366(1):23-31 JUNG B; GRAF H; ULLRICH V A NEW MONOOXYGENASE PRODUCT FROM 7-ETHOXYCOUMARIN AND ITS RELATION TO THE O-DEALKYLATION REACTION	6	3
5671	4	5337 1985 BLOOD 66(3):673-678 TAUBER AI; WRIGHT J; HIGSON FK; EDELMAN SA; WAXMAN DJ PURIFICATION AND CHARACTERIZATION OF THE HUMAN NEUTROPHIL NADH- CYTOCHROME-B5 REDUCTASE	13	3
5672	9	5370 1985 DRUG METABOLISM AND DISPOSITION 13(2):169-174 GORSKY LD; COON MJ EVALUATION OF THE ROLE OF FREE HYDROXYL RADICALS IN THE CYTOCHROME-P-450-CATALYZED OXIDATION OF BENZENE AND CYCLOHEXANOL	15	3
5673	19	5376 1985 ENDOCRINE RESEARCH 10(3-4):283-309 LAMBETH JD; STEVENS VL CYTOCHROME-P-450SCC - ENZYMOLOGY, AND THE REGULATION OF INTRAMITOCHONDRIAL CHOLESTEROL DELIVERY TO THE ENZYME	22	3
5674	7	5395 1985 FEDERATION PROCEEDINGS 44(1):130-133 ANDERSON KE; PANTUCK EJ; CONNEY AH; KAPPAS A NUTRIENT REGULATION OF CHEMICAL METABOLISM IN HUMANS	17	3
5675	3	5414 1985 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 33(3):471-479 TYNES RE; HODGSON E MAGNITUDE OF INVOLVEMENT OF THE MAMMALIAN FLAVIN-CONTAINING MONOOXYGENASE IN THE MICROSOMAL OXIDATION OF PESTICIDES	23	3
5676	6	5434 1985 JOURNAL OF BIOLOGICAL CHEMISTRY 260(9):5511-5517 WATABE S; KIMURA T ATP-DEPENDENT PROTEASE IN BOVINE ADRENAL-CORTEX - TISSUE- SPECIFICITY, SUBCELLULAR-LOCALIZATION, AND PARTIAL CHARACTERIZATION	60	3
5677	4	5450 1985 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 233(3):560-569 IGNARRO LJ; HARBISON RG; WOOD KS; WOLIN MS; MCNAMARA DB; HYMAN AL; KADOWITZ PJ DIFFERENCES IN RESPONSIVENESS OF INTRAPULMONARY ARTERY AND VEIN TO ARACHIDONIC-ACID - MECHANISM OF ARTERIAL RELAXATION INVOLVES CYCLIC GUANOSINE 3'-5'-MONOPHOSPHATE AND CYCLIC ADENOSINE 3'- 5'-MONOPHOSPHATE	64	3
5678	2	5474 1985 ORGANIC GEOCHEMISTRY 8(1):77-80 COOKSEY RC; GAITAN E; LINDSAY RH; HILL JB; KELLY K HUMIC SUBSTANCES, A POSSIBLE SOURCE OF ENVIRONMENTAL GOITROGENS	33	3
5679	13	5507 1985 XENOBIOTICA 15(4):333-342 DELAFORGE M; IOANNIDES C; PARKE DV LIGAND-COMPLEX FORMATION BETWEEN CYTOCHROME-P-450 AND CYTOCHROME-P448 AND METHYLENEDIOXYPHENYL COMPOUNDS	12	3
5680	3	5511 1985 XENOBIOTICA 15(7):591-597 DELMONTE M; CITTI L; GERVASI PG ISOPRENE METABOLISM BY LIVER MICROSOMAL MONOOXYGENASES	29	3
5681	4	5525 1986 AMERICAN JOURNAL OF PHYSIOLOGY 250(6):G800-G805 MATSUMURA T; KAUFFMAN FC; MEREN H; THURMAN RG O-2 UPTAKE IN PERIPORTAL AND PERICENTRAL REGIONS OF LIVER LOBULE IN PERFUSED LIVER	36	3
5682	8	5535 1986 AQUATIC TOXICOLOGY 8(4):231-241 KLEINOW KM; HAASCH ML; LECH JJ THE EFFECT OF TRICAINE ANESTHESIA UPON INDUCTION OF SELECT P- 450 DEPENDENT MONOOXYGENASE ACTIVITIES IN RAINBOW-TROUT (SALMO- GAIRDNERI)	20	3
5683	12	5543 1986 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 248(2):467-478 VELTMAN JC; MAINES MD ALTERATIONS OF HEME, CYTOCHROME-P-450, AND STEROID-METABOLISM BY MERCURY IN RAT ADRENAL	16	3
5684	19	5552 1986 BIOCHEMICAL ACTIONS OF HORMONES 13():129-166 PEDERSEN RC; BROWNIE AC THE MECHANISM OF ACTION OF ADRENOCORTICOTROPIC HORMONE ON CHOLESTEROL-METABOLISM IN THE ADRENAL-CORTEX	22	3
5685	7	5572 1986 BIOCHEMICAL PHARMACOLOGY 35(16):2663-2669 BELOQUI O; CEDERBAUM AI PREVENTION OF MICROSOMAL PRODUCTION OF HYDROXYL RADICALS, BUT NOT LIPID-PEROXIDATION, BY THE GLUTATHIONE-GLUTATHIONE PEROXIDASE SYSTEM	32	3
5686	7	5573 1986 BIOCHEMICAL PHARMACOLOGY 35(16):2775-2780 KUPFER D; BULGER WH; NANNI FJ CHARACTERISTICS OF THE ACTIVE OXYGEN IN COVALENT BINDING OF THE PESTICIDE METHOXYCHLOR TO HEPATIC-MICROSOMAL PROTEINS	5	3
5687	14	5580 1986 BIOCHEMICAL PHARMACOLOGY 35(24):4443-4448 BACKES WL; TURNER JL; HEIMANN TG; CANADY WJ ASSOCIATION OF HYDROPHOBIC SUBSTANCES WITH HEMIN - CHARACTERIZATION OF THE REVERSE TYPE-I BINDING SPECTRUM AND ITS RELATIONSHIP TO CYTOCHROME-P-450	5	3
5688	4	5609 1986 CHEMICA SCRIPTA 26(4):525-534 ERNSTER L OXYGEN AS AN ENVIRONMENTAL POISON	33	3
5689	7	5636 1986 DRUG METABOLISM AND DISPOSITION 14(6):643-648 WASKELL L; CANOVADAVIS E; PHILPOT R; PARANDOUSH Z; CHIANG JYL IDENTIFICATION OF THE ENZYMES CATALYZING METABOLISM OF METHOXYFLURANE	7	3
5690	15	5640 1986 ENDOCRINE RESEARCH 12(4):469-494 HORNSBY PJ CYTOCHROME-P-450 PSEUDOSUBSTRATE INTERACTIONS AND THE ROLE OF ANTIOXIDANTS IN THE ADRENAL-CORTEX	18	3
5691	5	5660 1986 GASTROENTEROLOGY 90(4):812-818 BURK RF; REITER R; LANE JM HYPERBARIC-OXYGEN PROTECTION AGAINST CARBON-TETRACHLORIDE HEPATOTOXICITY IN THE RAT - ASSOCIATION WITH ALTERED METABOLISM	17	3
5692	8	5700 1986 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 238(1):68-75 SHAPIRO BH; LECH GM; BARDALES RM PERSISTENT DEFECTS IN THE HEPATIC MONOOXYGENASE SYSTEM OF ADULT-RATS EXPOSED, PERINATALLY, TO MATERNALLY ADMINISTERED PHENYTOIN	14	3
5693	1	5738 1986 TOXICOLOGY AND APPLIED PHARMACOLOGY 83(2):287-293 VILLARRUEL MC; FERNANDEZ G; DEFERREYRA EC; DEFENOS OM; CASTRO JA LATE PREVENTIVE EFFECTS OF TRIFLUOPERAZINE ON CARBON TETRACHLORIDE-INDUCED HEPATIC-NECROSIS	19	3
5694	8	5743 1986 XENOBIOTICA 16(2):167-175 RUMYANTSEVA GV; SUSHKOV DG; WEINER LM MICROSOMAL OXIDATION OF 2-DIMETHYLAMINO-3-CHLORO-1,4- NAPHTHOQUINONE - THE POSSIBILITY OF SUBSTRATE ACTIVATION BY CYTOCHROME-P-450	6	3
5695	12	5744 1986 XENOBIOTICA 16(3):281-288 WELI AM; LINDEKE B PEROXIDATIVE N-OXIDATION AND N-DEALKYLATION REACTIONS OF PARGYLINE	12	3
5696	19	5745 1986 ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES 41(5-6):604-612 MULLERENOCH D; GRULER H THE ACTIVATION OF THE CYTOCHROME-P-450 DEPENDENT MONOOXYGENASE SYSTEM BY LIGHT	7	3
5697	8	5759 1987 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 252(1):218-228 DAVIS HW; SUZUKI T; SCHENKMAN JB OXIDATION OF ESTERIFIED ARACHIDONATE BY RAT-LIVER MICROSOMES	12	3
5698	5	5781 1987 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 148(2):857-863 JAISWAL AK; NEUHOLD LA; NEBERT DW HUMAN P450IA1 UPSTREAM REGULATORY SEQUENCES EXPRESSING THE CHLORAMPHENICOL ACETYLTRANSFERASE GENE - EFFECT OF HA-MSV ENHANCER AND COMPARISON OF TRANSIENT WITH STABLE TRANSFORMATION ASSAYS	4	3
5699	2	5791 1987 BIOCHEMICAL PHARMACOLOGY 36(8):1386-1388 WILLIAMS JB; NAPOLI JL INHIBITION OF RETINOIC ACID METABOLISM BY IMIDAZOLE ANTIMYCOTICS IN F9 EMBRYONAL CARCINOMA-CELLS	38	3
5700	5	5792 1987 BIOCHEMICAL PHARMACOLOGY 36(10):1637-1643 BOEYNAEMS JM; DEMOLLE D; VANCOEVORDEN A STIMULATION OF VASCULAR PROSTACYCLIN BY SKF525-A (PROADIFEN) AND RELATED-COMPOUNDS	12	3

#	Cited nodes	Nodes / Authors	GCS	LCS
5701	6	5794 1987 BIOCHEMICAL PHARMACOLOGY 36(12):1973-1978 TAN YH; KEEFER LK; YANG CS INHIBITION OF MICROSOMAL N-NITROSODIMETHYLAMINE DEMETHYLASE BY DIETHYL-ETHER AND OTHER ANESTHETICS	12	3
5702	2	5812 1987 BIOCHEMISTRY 26(17):5465-5471 BRASH AR; INGRAM CD; HARRIS TM ANALYSIS OF A SPECIFIC OXYGENATION REACTION OF SOYBEAN LIPOXYGENASE-1 WITH FATTY-ACIDS ESTERIFIED IN PHOSPHOLIPIDS	85	3
5703	13	5829 1987 BIOCHIMICA ET BIOPHYSICA ACTA 926(3):231-238 TAMURA S; KAWATA S; SUGIYAMA T; TARUI S MODULATION OF THE REDUCTIVE METABOLISM OF HALOTHANE BY MICROSOMAL CYTOCHROME-B5 IN RAT-LIVER	5	3
5704	12	5860 1987 CHEMISTRY AND PHYSICS OF LIPIDS 45(2-4):143-169 COMPORTI M GLUTATHIONE DEPLETING AGENTS AND LIPID-PEROXIDATION	99	3
5705	5	5861 1987 CHEMISTRY AND PHYSICS OF LIPIDS 45(2-4):171-205 UNGEMACH FR PATHOBIOCHEMICAL MECHANISMS OF HEPATOCELLULAR DAMAGE FOLLOWING LIPID-PEROXIDATION	49	3
5706	32	5867 1987 CRC CRITICAL REVIEWS IN TOXICOLOGY 18(1):27-79 HORTON AA; FAIRHURST S LIPID-PEROXIDATION AND MECHANISMS OF TOXICITY	188	3
5707	5	5881 1987 DRUG METABOLISM AND DISPOSITION 15(5):731-733 GALINSKY RE; ALEXANDER DP; FRANKLIN MR EFFECT OF CYCLOSPORINE ON HEPATIC OXIDATIVE AND CONJUGATIVE METABOLISM IN RATS	9	3
5708	2	5894 1987 EXPERIMENTAL AND MOLECULAR PATHOLOGY 46(2):180-189 SHERTZER HG; NIEMI MP; REITMAN FA; BERGER ML; MYERS BL; TABOR MW PROTECTION AGAINST CARBON-TETRACHLORIDE HEPATOTOXICITY BY PRETREATMENT WITH INDOLE-3-CARBINOL	21	3
5709	9	5933 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 28(3):327-332 SAMANTA TB; GHOSH DK CHARACTERIZATION OF PROGESTERONE 11-ALPHA-HYDROXYLASE OF ASPERGILLUS-OCHRACEUS TS - A CYTOCHROME-P-450 LINKED MONOOXYGENASE	21	3
5710	10	5935 1987 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 28(5):533-541 THERON CN; RUSSELL VA; TALJAARD JJF ESTROGEN-2-4-HYDROXYLASE ACTIVITIES IN RAT-BRAIN AND LIVER- MICROSOMES EXHIBIT DIFFERENT SUBSTRATE PREFERENCES AND SENSITIVITIES TO INHIBITION	8	3
5711	4	5940 1987 LIFE SCIENCES 41(9):1141-1148 WILLIAMS MT; LEONARD D; SIMONET L EFFECTS OF PREGNENOLONE-16-ALPHA-CARBONITRILE ON DRUG- METABOLIZING-ENZYMES IN HYPOPHYSECTOMIZED FEMALE RATS	6	3
5712	6	5943 1987 MOLECULAR AND CELLULAR ENDOCRINOLOGY 52(3):169-176 MENDELSON CR; SIMPSON ER REGULATION OF ESTROGEN BIOSYNTHESIS BY HUMAN ADIPOSE-CELLS INVITRO	17	3
5713	6	5963 1987 PHARMACOLOGY 34(5):241-249 GALBRAITH RA; DRUMMOND GS; KREY L; KAPPAS A RELATIONSHIP OF SUPPRESSION OF THE ANDROGENIC AXIS BY COBALT- PROTOPORPHYRIN TO ITS EFFECTS ON WEIGHT-LOSS AND HEPATIC HEME OXYGENASE INDUCTION	17	3
5714	7	5979 1987 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 57(3):375-387 RABOVSKY J; JUDY DJ CYTOCHROME-P450-DEPENDENT ALKOXYPHENOXAZONE DEALKYLASE ACTIVITIES IN LUNG MICROSOMES FROM UNTREATED AND BETA- NAPHTHOFLAVONE-TREATED RATS - EFFECT OF INVITRO INHIBITORS	12	3
5715	10	5998 1987 XENOBIOTICA 17(4):513-522 LOCK EA; STONARD MD; ELCOMBE CR THE INDUCTION OF OMEGA-OXIDATION AND BETA-OXIDATION OF FATTY- ACIDS AND EFFECT ON ALPHA-2U-GLOBULIN CONTENT IN THE LIVER AND KIDNEY OF RATS ADMINISTERED 2,2,4-TRIMETHYLPENTANE	14	3
5716	12	6001 1987 XENOBIOTICA 17(7):793-805 KAO LR; WILKINSON CF INHIBITION OF CYTOCHROME-P-450C-MEDIATED BENZO[A]PYRENE HYDROXYLASE AND ETHOXYRESORUFIN O-DEETHYLASE BY DIHYDROSAFROLE	5	3
5717	9	6062 1988 BIOCHEMICAL JOURNAL 254(1):101-108 HEIRWEGH KPM; MEUWISSEN JATP; VERMEIR M; DESMEDT H LIPOSOMES AS CARRIERS OF POORLY WATER-SOLUBLE SUBSTRATES - LINEAR MODELING OF MEMBRANE SYSTEMS WITH CATALYTIC OR BINDING- SITES OF DIFFERENT FACEDNESS - SIGNIFICANCE OF EXPERIMENTAL MEMBRANE PARTITION-COEFFICIENTS AND OF KINETIC AND EQUILIBRIUM PARAMETERS	18	3
5718	4	6070 1988 BIOCHEMICAL PHARMACOLOGY 37(2):333-338 SHERTZER HG; BERGER ML; TABOR MW INTERVENTION IN FREE-RADICAL MEDIATED HEPATOTOXICITY AND LIPID- PEROXIDATION BY INDOLE-3-CARBINOL	53	3
5719	7	6189 1988 DRUG METABOLISM AND DISPOSITION 16(6):823-828 KYEREMATEN GA; OWENS GF; CHATTOPADHYAY B; DEBETHIZY JD; VESELL ES SEXUAL DIMORPHISM OF NICOTINE METABOLISM AND DISTRIBUTION IN THE RAT - STUDIES INVIVO AND INVITRO	33	3
5720	11	6193 1988 ENDOCRINOLOGY 122(1):291-295 SASANO H; WHITE PC; NEW MI; SASANO N IMMUNOHISTOCHEMISTRY OF CYTOCHROME-P-450 21-HYDROXYLASE - MICROSCOPIC EXAMINATION OF THE ENZYME IN THE BOVINE ADRENAL- CORTEX AND KIDNEY	18	3
5721	2	6203 1988 GASTROENTEROLOGY 95(4):1130-1143 TRABER PG; CHIANALE J; GUMUCIO JJ PHYSIOLOGIC SIGNIFICANCE AND REGULATION OF HEPATOCELLULAR HETEROGENEITY	55	3
5722	8	6232 1988 JOURNAL OF BIOLOGICAL CHEMISTRY 263(18):8925-8928 KAGIMOTO M; KAGIMOTO K; SIMPSON ER; WATERMAN MR TRANSCRIPTION OF THE BOVINE ADRENODOXIN GENE PRODUCES 2 SPECIES OF MESSENGER-RNA OF WHICH ONLY ONE IS TRANSLATED INTO ADRENODOXIN	11	3
5723	2	6255 1988 JOURNAL OF PATHOLOGY 156(2):101-110 WILLIAMS KI; HIGGS GA EICOSANOIDS AND INFLAMMATION	57	3
5724	7	6285 1988 MOLECULAR PHARMACOLOGY 34(4):597-603 PETERSON FJ; HOLTZMAN JL; CRANKSHAW D; MASON RP 2 SITES OF AZO REDUCTION IN THE MONOOXYGENASE SYSTEM	13	3
5725	14	6288 1988 MUTATION RESEARCH 197(2):273-288 HIGASHI K METABOLIC-ACTIVATION OF ENVIRONMENTAL CHEMICALS BY MICROSOMAL- ENZYMES OF HIGHER-PLANTS	41	3
5726	2	6289 1988 MUTATION RESEARCH 202(1):269-276 ZIELENSKA M; GUTTENPLAN JB MUTAGENIC ACTIVITY AND SPECIFICITY OF N-NITROSOMETHYLANILINE AND N-NITROSODIPHENYLAMINE IN SALMONELLA	16	3
5727	9	6312 1988 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 59(3):403-406 RODRIGUES AD; WADDELL PR; IOANNIDES C INHIBITION OF THE RAT HEPATIC MIXED-FUNCTION OXIDASES BY INVIVO ADMINISTRATION OF CLOTRIMAZOLE	4	3
5728	5	6341 1988 XENOBIOTICA 18(10):1109-1118 HODEK P; JANSCAK P; ANZENBACHER P; BURKHARD J; JANKU J; VODICKA L METABOLISM OF DIAMANTANE BY RAT-LIVER MICROSOMAL CYTOCHROMES-P- 450	21	3
5729	6	6351 1989 AMERICAN JOURNAL OF PHYSIOLOGY 257(6):L411-L420 ISCHIROPOULOS H; NADZIEJKO CE; KUMAE T; KIKKAWA Y OXYGEN TOLERANCE IN NEONATAL RATS - ROLE OF SUBCELLULAR SUPEROXIDE GENERATION	19	3
5730	10	6390 1989 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 273(1):137-143 MINOTTI G TERT-BUTYL HYDROPEROXIDE-DEPENDENT MICROSOMAL RELEASE OF IRON AND LIPID-PEROXIDATION .1. EVIDENCE FOR THE REDUCTIVE RELEASE OF NONHEME, NONFERRITIN IRON	25	3
5731	7	6412 1989 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 161(3):1042-1048 ISCHIROPOULOS H; KUMAE T; KIKKAWA Y EFFECT OF INTERFERON INDUCERS ON SUPEROXIDE ANION GENERATION FROM RAT-LIVER MICROSOMES DETECTED BY LUCIGENIN CHEMI- LUMINESCENCE	19	3
5732	4	6420 1989 BIOCHEMICAL JOURNAL 259(2):561-568 GRAY RW; GHAZARIAN JG SOLUBILIZATION AND RECONSTITUTION OF KIDNEY 25-HYDROXYVITAMIN- D3 1-ALPHA-HYDROXYLASE AND 24-HYDROXYLASE FROM VITAMIN-D- REPLETE PIGS	30	3
5733	6	6423 1989 BIOCHEMICAL JOURNAL 262(1):91-95 ELDREDGE ER; JACKSON B; SUCKLING KE; WOLF CR INHIBITION OF CHOLESTEROL 7-ALPHA-HYDROXYLASE BY AN ANTIBODY TO A MALE-SPECIFIC FORM OF CYTOCHROME-P-450 FROM SUBFAMILY P450IIC	6	3
5734	1	6441 1989 BIOCHEMICAL PHARMACOLOGY 38(16):2719-2725 ALBANO E; CARINI R; PAROLA M; BELLOMO G; GORIAGATTI L; POLI G; DIANZANI MU EFFECTS OF CARBON-TETRACHLORIDE ON CALCIUM HOMEOSTASIS - A CRITICAL RECONSIDERATION	23	3
5735	3	6443 1989 BIOCHEMICAL PHARMACOLOGY 38(20):3565-3572 BIGELOW SW; COLLINS AC; NEBERT DW SELECTIVE MOUSE BREEDING FOR SHORT ETHANOL SLEEP TIME HAS LED TO HIGH-LEVELS OF HEPATIC AROMATIC HYDROCARBON (AH) RECEPTOR	7	3
5736	3	6451 1989 BIOCHEMICAL SOCIETY TRANSACTIONS 17(1):192-193 GRIFFITH CJ; PALMER CNA; SANTISTEBAN I; HUTTER A; SHEPHARD EA; PHILLIPS IR STRUCTURE AND EXPRESSION OF HUMAN CYTOCHROME-P-450 GENES	3	3
5737	0	6454 1989 BIOCHEMICAL SOCIETY TRANSACTIONS 17(6):1025-1026 SWART P; ESTABROOK RW; MASON JI; WATERMAN MR CATALYTIC ACTIVITY OF HUMAN AND BOVINE ADRENAL CYTOCHROMES-P- 45017-ALPHA,LYASE EXPRESSED IN COS-1 CELLS	3	3
5738	3	6487 1989 BIOCHIMICA ET BIOPHYSICA ACTA 996(3):214-225 MODI S; BEHERE DV; MITRA S BINDING OF AROMATIC DONOR MOLECULES TO LACTOPEROXIDASE - PROTON NMR AND OPTICAL-DIFFERENCE SPECTROSCOPIC STUDIES	45	3
5739	4	6493 1989 BIOTECHNOLOGY AND BIOENGINEERING 34(5):660-670 SIANO SA; MUTHARASAN R NADH AND FLAVIN FLUORESCENCE RESPONSES OF STARVED YEAST CULTURES TO SUBSTRATE ADDITIONS	16	3
5740	1	6504 1989 CANCER RESEARCH 49(7):1676-1681 ANDERSON LM; JONES AB; RIGGS CW; KOVATCH RM MODIFICATION OF TRANS-PLACENTAL TUMORIGENESIS BY 3- METHYLCHOLANTHRENE IN MICE BY GENOTYPE AT THE AH LOCUS AND PRETREATMENT WITH BETA-NAPHTHOFLAVONE	14	3
5741	4	6534 1989 CHEMISTRY AND PHYSICS OF LIPIDS 51(1):15-22 FAHLSTADIUS P; HAMBERG M A GAS-LIQUID-CHROMATOGRAPHIC METHOD FOR STERIC ANALYSIS OF EPOXY ACIDS	15	3
5742	1	6544 1989 DEVELOPMENTAL PHARMACOLOGY AND THERAPEUTICS 13(2-4):63-69 LEROUX JP; CRESTEIL T; MARIE S ONTOGENY AND REGULATION OF DRUG-METABOLISM IN HUMANS .1. MONOOXYGENASES	7	3
5743	4	6555 1989 DRUG METABOLISM AND DISPOSITION 17(1):64-68 NIWA T; TOKUMA Y; NAKAGAWA K; NOGUCHI H STEREOSELECTIVE OXIDATION OF NILVADIPINE, A NEW DIHYDROPYRIDINE CALCIUM-ANTAGONIST, IN RAT AND DOG LIVER	11	3
5744	13	6559 1989 DRUG METABOLISM AND DISPOSITION 17(4):449-454 MURRAY M; REIDY GF INVITRO FORMATION OF AN INHIBITORY COMPLEX BETWEEN AN ISOSAFROLE METABOLITE AND RAT HEPATIC CYTOCHROME-P-450 PB-B	11	3
5745	8	6571 1989 DRUG METABOLISM REVIEWS 20(2-4):733-748 GUENTHNER TM; QATO M; WHALEN R; GLOMB S SIMILARITIES BETWEEN CATALASE AND CYTOSOLIC EPOXIDE HYDROLASE	3	3
5746	7	6615 1989 INTERNATIONAL JOURNAL OF DERMATOLOGY 28(8):493-496 JANSSEN PAJ; VANDENBOSSCHE HFA; VANWAUWE JP; CAUWENBERGH GFMJ; DEGREEF HJ THE ROLE OF CYTOCHROME-P-450 IN DERMATOLOGY	9	3
5747	7	6619 1989 JOURNAL OF APPLIED PHYSIOLOGY 67(6):2586-2592 HAZINSKI TA; FRANCE M; KENNEDY KA; HANSEN TN CIMETIDINE REDUCES HYPEROXIC LUNG INJURY IN LAMBS	13	3
5748	8	6638 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(16):9250-9257 ATOR MA; DAVID SK; DEMONTELLANO PRO STABILIZED ISOPORPHYRIN INTERMEDIATES IN THE INACTIVATION OF HORSERADISH-PEROXIDASE BY ALKYLHYDRAZINES	31	3
5749	1	6642 1989 JOURNAL OF BIOLOGICAL CHEMISTRY 264(21):12299-12302 POU S; COHEN MS; BRITIGAN BE; ROSEN GM SPIN-TRAPPING AND HUMAN-NEUTROPHILS - LIMITS OF DETECTION OF HYDROXYL RADICAL	60	3
5750	2	6660 1989 JOURNAL OF CLINICAL INVESTIGATION 83(4):1326-1335 KENNEDY TP; RAO NV; HOPKINS C; PENNINGTON L; TOLLEY E; HOIDAL JR ROLE OF REACTIVE OXYGEN SPECIES IN REPERFUSION INJURY OF THE RABBIT LUNG	158	3
5751	10	6669 1989 JOURNAL OF INORGANIC BIOCHEMISTRY 37(2):111-118 RISTAU O; WAGNEROVA DM; REIN H; RUCKPAUL K DEMETHYLATION OF TERTIARY-AMINES BY A RECONSTITUTED CYTOCHROME- P-450 ENZYME-SYSTEM - KINETICS OF OXYGEN-CONSUMPTION AND HYDROGEN-PEROXIDE FORMATION	4	3
5752	4	6687 1989 LIFE SCIENCES 44(19):1387-1393 CASHMAN JR 5,6-EPOXYEICOSATRIENOIC ACID STIMULATES GROWTH-HORMONE RELEASE IN RAT ANTERIOR-PITUITARY CELLS	10	3
5753	10	6699 1989 MOLECULAR BIOLOGY & MEDICINE 6(2):169-178 WHITLOCK JP; DENISON MS; FISHER JM; SHEN ES INDUCTION OF HEPATIC CYTOCHROME-P450 GENE-EXPRESSION BY 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN	28	3
5754	4	6722 1989 MUTAGENESIS 4(4):292-296 ROSCHER E; WIEBEL FJ H4IIEC3 RAT HEPATOMA-CELLS ACTIVATE N-NITROSODIMETHYLAMINE BUT ARE RESISTANT TO THE GENOTOXIC PRODUCTS	5	3
5755	5	6723 1989 MUTATION RESEARCH 212(2):275-284 LUBET RA; MCKINNEY CE; CAMERON JW; GUENGERICH FP; NIMS RW PREFERENTIAL ACTIVATION OF 6-AMINOCHRYSENE AND 2- AMINOANTHRACENE TO MUTAGENIC MOIETIES BY DIFFERENT FORMS OF CYTOCHROME P450 IN HEPATIC 9000XG SUPERNATANTS FROM THE RAT	13	3
5756	9	6738 1989 PHARMACOLOGICAL RESEARCH 21(5):513-520 MIYATA M; NAGATA K; YAMAZOE Y; KATO R ISOLATION AND CHARACTERIZATION OF HUMAN-LIVER CYTOCHROME-B5 CDNA	9	3
5757	4	6766 1989 TOXICOLOGY 59(2):179-194 KAHL R; WEINKE S; KAPPUS H PRODUCTION OF REACTIVE OXYGEN SPECIES DUE TO METABOLIC- ACTIVATION OF BUTYLATED HYDROXYANISOLE	37	3
5758	2	6787 1989 XENOBIOTICA 19(10):1037-1039 LIVINGSTONE DR; STEGEMAN JJ CYTOCHROME-P-450 FORMS AND FUNCTIONS IN ANIMALS	6	3
5759	4	6847 1990 ARCHIVES OF TOXICOLOGY 64(2):157-160 BRADY JF; XIAO F; NING SM; YANG CS METABOLISM OF METHYL TERTIARY-BUTYL ETHER BY RAT HEPATIC MICROSOMES	49	3
5760	7	6849 1990 ARCHIVES OF TOXICOLOGY 64(5):365-369 ELOVAARA E; VAINIO H; AITIO A PULMONARY TOXICITY OF INHALED STYRENE IN ACETONE-TREATED, PHENOBARBITAL-TREATED AND 3-METHYLCHOLANTHRENE-TREATED RATS	9	3
5761	3	6852 1990 ATLA-ALTERNATIVES TO LABORATORY ANIMALS 18():251-258 BLAAUBOER BJ; WORTELBOER HM; MENNES WC THE USE OF LIVER-CELL CULTURES DERIVED FROM DIFFERENT MAMMALIAN-SPECIES IN INVITRO TOXICOLOGICAL STUDIES - IMPLEMENTATION IN EXTRAPOLATION MODELS	16	3
5762	9	6860 1990 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 172(3):1331-1337 PERNECKY SJ; PORTER TD; COON MJ EXPRESSION OF RABBIT CYTOCHROME-P-450IIE2 IN YEAST AND STABILIZATION OF THE ENZYME BY 4-METHYLPYRAZOLE	6	3
5763	4	6887 1990 BIOCHEMICAL PHARMACOLOGY 40(3):545-550 LARREY D; TINEL M; LETTERON P; MAUREL P; LOEPER J; BELGHITI J; PESSAYRE D METABOLIC-ACTIVATION OF THE NEW TRICYCLIC ANTIDEPRESSANT TIANEPTINE BY HUMAN LIVER CYTOCHROME-P450	18	3
5764	8	6900 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(1):26-28 WATERMAN MR; LUND J; AHLGREN R; WU D; SIMPSON ER REGULATION OF STEROID HYDROXYLASE GENE-EXPRESSION AND STEROID- HORMONE BIOSYNTHESIS	12	3
5765	4	6904 1990 BIOCHEMICAL SOCIETY TRANSACTIONS 18(4):615-616 PALMER CNA; SHEPHARD EA; PHILLIPS IR QUANTIFICATION OF CYTOCHROME-P-450 GENE-EXPRESSION IN HUMAN TISSUES	6	3
5766	1	6930 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1018(2-3):142-146 WESTERHOFF HV; AON MA; VANDAM K; CORTASSA S; KAHN D; VANWORKUM M DYNAMIC AND HIERARCHICAL COUPLING	15	3
5767	3	6938 1990 BIOCHIMICA ET BIOPHYSICA ACTA 1041(1):83-93 SAXENA A; MODI S; BEHERE DV; MITRA S INTERACTION OF AROMATIC DONOR MOLECULES WITH MANGANESE(III) RECONSTITUTED HORSERADISH-PEROXIDASE - PROTON NUCLEAR-MAGNETIC- RESONANCE AND OPTICAL-DIFFERENCE SPECTROSCOPIC STUDIES	15	3
5768	13	6961 1990 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 68(12):1533-1541 RIDDICK DS; MCGILVRAY I; MARKS GS INACTIVATION OF RAT-LIVER MICROSOMAL STEROID HYDROXYLATIONS BY 4-ALKYL ANALOGS OF 3,5-DIETHOXYCARBONYL-1,4-DIHYDRO-2,4,6- TRIMETHYLPYRIDINE - EVIDENCE FOR SELECTIVITY AMONG STEROID- INDUCIBLE CYTOCHROME-P450IIIA FORMS	8	3
5769	7	6963 1990 CANCER LETTERS 52(3):235-241 BENGTSSON M; HALLBERG E; GEORGELLIS A; RYDSTROM J ON THE IDENTITY OF THE XENOBIOTIC-METABOLIZING FORM(S) OF CYTOCHROME-P-450 IN ENDOCRINE ORGANS	6	3
5770	20	7009 1990 CRITICAL REVIEWS IN TOXICOLOGY 21(1):1-20 MAINES MD EFFECT OF CISPLATINUM ON HEME, DRUG, AND STEROID-METABOLISM PATHWAYS - POSSIBLE INVOLVEMENT IN NEPHROTOXICITY AND INFERTILITY	11	3
5771	2	7072 1990 FEBS LETTERS 270(1-2):177-180 MYASOEDOVA KN; BERNDT P IMMOBILIZED CYTOCHROME-P-450LM2 - DISSOCIATION AND REASSOCIATION OF OLIGOMERS	9	3
5772	2	7075 1990 FEBS LETTERS 275(1-2):33-35 USANOV SA; CHERNOGOLOV AA; CHASHCHIN VL IS CYTOCHROME P-450SCC A TRANSMEMBRANE PROTEIN	17	3
5773	7	7078 1990 FUNDAMENTAL & CLINICAL PHARMACOLOGY 4(6):595-615 MEYER UA GENETIC POLYMORPHISMS OF DRUG-METABOLISM	23	3
5774	2	7122 1990 JOURNAL OF BIOLOGICAL CHEMISTRY 265(2):652-659 YAMAZAKI I; PIETTE LH; GROVER TA KINETIC-STUDIES ON SPIN TRAPPING OF SUPEROXIDE AND HYDROXYL RADICALS GENERATED IN NADPH-CYTOCHROME-P-450 REDUCTASE-PARAQUAT SYSTEMS - EFFECT OF IRON CHELATES	51	3
5775	9	7154 1990 JOURNAL OF CELLULAR BIOCHEMISTRY 43(2):149-159 KUHNVELTEN WN A MICROCOMPARTMENTATION ANALYSIS OF INTERMEDIATE LEAKAGE RESPONSE TO SUBSTRATE EXCESS IN A MEMBRANE-BOUND BIFUNCTIONAL ENZYME - LOCAL-CONTROL OF HYDROXYPROGESTERONE CHANNELING EFFICIENCY DURING CYTOCHROME P450XVII-CATALYZED ANDROGEN BIOSYNTHESIS	4	3
5776	9	7156 1990 JOURNAL OF CHROMATOGRAPHY 498(2):293-302 AZERAD R; BOUCHER JL; DANSETTE P; DELAFORGE M HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF 11- HYDROXYLAURIC ACID ENANTIOMERS - APPLICATION TO THE DETERMINATION OF THE STEREOCHEMISTRY OF MICROSOMAL LAURIC ACID (OMEGA-1) HYDROXYLATION	11	3
5777	7	7184 1990 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 255(2):577-583 GALINSKY RE; JOHNSON DH; KANE RE; FRANKLIN MR EFFECT OF AGING ON HEPATIC BIOTRANSFORMATION IN FEMALE FISCHER 344 RATS - CHANGES IN SULFOTRANSFERASE ACTIVITIES ARE CONSISTENT WITH KNOWN GENDER-RELATED CHANGES IN PITUITARY GROWTH-HORMONE SECRETION IN AGING ANIMALS	10	3
5778	2	7209 1990 LIPIDS 25(12):849-853 GERMAN JB; BERGER R FORMATION OF 8,15-DIHYDROXY EICOSATETRAENOIC ACID VIA 15- LIPOXYGENASE AND 12-LIPOXYGENASE IN FISH GILL	17	3
5779	2	7224 1990 MOLECULAR AND CELLULAR ENDOCRINOLOGY 69(1):51-57 DENISON MS; DEAL RM THE BINDING OF TRANSFORMED AROMATIC HYDROCARBON (AH) RECEPTOR TO ITS DNA RECOGNITION SITE IS NOT AFFECTED BY METAL DEPLETION	42	3
5780	3	7230 1990 MOLECULAR ENDOCRINOLOGY 4(8):1144-1152 SZYF M; MILSTONE DS; SCHIMMER BP; PARKER KL; SEIDMAN JG CIS MODIFICATION OF THE STEROID 21-HYDROXYLASE GENE PREVENTS ITS EXPRESSION IN THE Y1 MOUSE ADRENOCORTICAL TUMOR-CELL LINE	51	3
5781	14	7366 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 288(1):64-70 SCHWEIZER M; PETER MA; FILIPOVIC D; TINNER R; BOSSHARD HR; OERTLE M MECHANISM OF MONOCLONAL-ANTIBODY INHIBITION/STIMULATION OF REACTIONS CATALYZED BY CYTOCHROME-P450IIB1	7	3
5782	9	7372 1991 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 291(1):24-30 OERTLE M; FILIPOVIC D; RICHTER C; WINTERHALTER KH; DIIORIO EE ISOELECTRIC-FOCUSING OF CYTOCHROME-P450 - ISOLATION OF 6 PHENOBARBITAL-INDUCIBLE RAT-LIVER MICROSOMAL ISOENZYMES	5	3
5783	6	7405 1991 BIOCHEMICAL PHARMACOLOGY 41(4):635-638 KETTERER B; MEYER DJ; LALOR E; JOHNSON P; GUENGERICH FP; DISTLERATH LM; REILLY PEB; KADLUBAR FF; FLAMMANG TJ; YAMAZOE Y; BEAUNE PH A COMPARISON OF LEVELS OF GLUTATHIONE TRANSFERASES, CYTOCHROMES-P450 AND ACETYLTRANSFERASES IN HUMAN LIVERS	13	3
5784	15	7440 1991 BIOCHEMISTRY 30(34):8323-8330 ADDYA S; ZHENG YM; SHAYIQ RM; FAN JY; AVADHANI NG CHARACTERIZATION OF A FEMALE-SPECIFIC HEPATIC MITOCHONDRIAL CYTOCHROME-P-450 WHOSE STEADY-STATE LEVEL IS MODULATED BY TESTOSTERONE	14	3
5785	14	7444 1991 BIOCHEMISTRY 30(50):11646-11653 SAMOKYSZYN VM; DEMONTELLANO PRO TOPOLOGY OF THE CHLOROPEROXIDASE ACTIVE-SITE - REGIOSPECIFICITY OF HEME MODIFICATION BY PHENYLHYDRAZINE AND SODIUM-AZIDE	21	3
5786	5	7457 1991 BIOCHIMICA ET BIOPHYSICA ACTA 1092(3):284-290 KALAPOS MP; GARZO T; ANTONI F; MANDL J EFFECT OF METHYLGLYOXAL ON GLUCOSE FORMATION, DRUG OXIDATION AND GLUTATHIONE CONTENT IN ISOLATED MURINE HEPATOCYTES	17	3
5787	3	7487 1991 CARCINOGENESIS 12(2):305-310 BALL RW; COULOMBE RA COMPARATIVE BIOTRANSFORMATION OF AFLATOXIN-B1 IN MAMMALIAN AIRWAY EPITHELIUM	20	3
5788	3	7488 1991 CARCINOGENESIS 12(3):401-404 ROBERTS AE; KEDDERIS GL; TURNER MJ; RICKERT DE; SWENBERG JA SPECIES COMPARISON OF ACRYLONITRILE EPOXIDATION BY MICROSOMES FROM MICE, RATS AND HUMANS - RELATIONSHIP TO EPOXIDE CONCENTRATIONS IN MOUSE AND RAT-BLOOD	36	3
5789	5	7489 1991 CARCINOGENESIS 12(4):697-702 HAJOS AKD; WINSTON GW DINITROPYRENE NITROREDUCTASE ACTIVITY OF PURIFIED NAD(P)H- QUINONE OXIDOREDUCTASE - ROLE IN RAT-LIVER CYTOSOL AND INDUCTION BY AROCLOR-1254 PRETREATMENT	35	3
5790	8	7504 1991 CHEMISTRY LETTERS (6):973-976 HIROYA K; SHIMIZU T; HATANO M; FUJIIKURIYAMA Y REMARKABLE CHANGES IN CATALYTIC ACTIVITY TOWARD TESTOSTERONE OF ENGINEERED CYTOCHROME P-450D BY MUTATIONS AT PUTATIVE DISTAL SITE	5	3
5791	6	7512 1991 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 100(1-2):151-155 LIVINGSTONE DR TOWARDS A SPECIFIC INDEX OF IMPACT BY ORGANIC POLLUTION FOR MARINE-INVERTEBRATES	43	3
5792	6	7513 1991 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY 100(3):327-338 BORLAKOGLU JT COMPARATIVE ASPECTS ON THE BIOACCUMULATION, METABOLISM AND TOXICITY WITH PCBS	30	3
5793	5	7515 1991 CRITICAL REVIEWS IN TOXICOLOGY 21(4):265-294 TJALVE H THE TISSUE DISTRIBUTION AND THE TISSUE-SPECIFICITY OF BIOACTIVATION OF SOME TOBACCO-SPECIFIC AND SOME OTHER N- NITROSAMINES	20	3
5794	6	7534 1991 DRUG METABOLISM AND DISPOSITION 19(2):498-502 MANNING BW; FRANKLIN MR; GALINSKY RE DRUG-METABOLIZING ENZYME CHANGES AFTER CHRONIC BUTHIONINE SULFOXIMINE EXPOSURE MODIFY ACETAMINOPHEN DISPOSITION IN RATS	5	3
5795	5	7539 1991 DRUG METABOLISM AND DISPOSITION 19(6):1016-1021 SHEN TL; ZHUANG ZP; MCCAULEY R; PUTT D; HOLLENBERG PF DIFFERENTIAL-EFFECTS OF PROTEINASE K ON THE COMPONENTS OF THE LIVER MICROSOMAL CYTOCHROME-P-450 MIXED-FUNCTION OXIDASE SYSTEM	5	3
5796	24	7558 1991 EUROPEAN JOURNAL OF BIOCHEMISTRY 197(2):381-390 KUHNVELTEN WN THERMODYNAMICS AND MODULATION OF PROGESTERONE MICROCOMPARTMENTATION AND HYDROPHOBIC INTERACTION WITH CYTOCHROME-P450XVII BASED ON QUANTIFICATION OF LOCAL LIGAND CONCENTRATIONS IN A COMPLEX MULTICOMPONENT SYSTEM	11	3
5797	11	7614 1991 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 23(6):823-854 HANSFORD RG DEHYDROGENASE ACTIVATION BY CA2+ IN CELLS AND TISSUES	93	3
5798	14	7635 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(28):18600-18605 ETTER HU; RICHTER C; OHTA Y; WINTERHALTER KH; SASABE H; KAWATO S ROTATION AND INTERACTION WITH EPOXIDE HYDRASE OF CYTOCHROME-P- 450 IN PROTEOLIPOSOMES	20	3
5799	3	7639 1991 JOURNAL OF BIOLOGICAL CHEMISTRY 266(31):20899-20906 WAINWRIGHT SL; POWELL WS MECHANISM FOR THE FORMATION OF DIHYDRO METABOLITES OF 12- HYDROXYEICOSANOIDS - CONVERSION OF LEUKOTRIENE-B4 AND 12- HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID TO 12-OXO INTERMEDIATES	36	3
5800	2	7646 1991 JOURNAL OF CELL SCIENCE 99():325-334 AON MA; CORTASSA S; WESTERHOFF HV; BERDEN JA; VANSPRONSEN E; VANDAM K DYNAMIC REGULATION OF YEAST GLYCOLYTIC OSCILLATIONS BY MITOCHONDRIAL FUNCTIONS	27	3

#	Cited nodes	Nodes / Authors	GCS	LCS
5801	9	7656 1991 JOURNAL OF CLINICAL INVESTIGATION 88(6):1865-1872 KUNDU RK; TONSGARD JH; GETZ GS INDUCTION OF OMEGA-OXIDATION OF MONOCARBOXYLIC ACIDS IN RATS BY ACETYLSALICYLIC-ACID	16	3
5802	3	7672 1991 JOURNAL OF NUTRITION 121(12):2037-2043 MCINTOSH MK; BERDANIER CD ANTIOBESITY EFFECTS OF DEHYDROEPIANDROSTERONE ARE MEDIATED BY FUTILE SUBSTRATE CYCLING IN HEPATOCYTES OF BHE CDB RATS	36	3
5803	4	7676 1991 JOURNAL OF PHARMACOBIO-DYNAMICS 14(3):132-138 ISHIKAWA M; SASAKI K; OZAKI M; WATANABE K; TAKAYANAGI Y; SASAKI K HEPATIC DRUG-METABOLIZING ACTIVITY IN RATS WITH CARRAGEENAN- INDUCED INFLAMMATION	11	3
5804	3	7681 1991 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 259(2):789-798 TURGEON J; FISET C; GIGUERE R; GILBERT M; MOERIKE K; ROULEAU JR; KROEMER HK; EICHELBAUM M; GRECHBELANGER O; BELANGER PM INFLUENCE OF DEBRISOQUINE PHENOTYPE AND OF QUINIDINE ON MEXILETINE DISPOSITION IN MAN	29	3
5805	2	7684 1991 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 38(5):599-609 MARRERO M; PROUGH RA; PUTNAM RS; BENNETT M; MILEWICH L INHIBITION OF CARBAMOYL PHOSPHATE SYNTHETASE-I BY DIETARY DEHYDROEPIANDROSTERONE	6	3
5806	2	7717 1991 MOLECULAR & GENERAL GENETICS 227(2):238-244 HARDER PA; OKEEFE DP; ROMESSER JA; LETO KJ; OMER CA ISOLATION AND CHARACTERIZATION OF STREPTOMYCES-GRISEOLUS DELETION MUTANTS AFFECTED IN CYTOCHROME-P-450-MEDIATED HERBICIDE METABOLISM	9	3
5807	3	7719 1991 MOLECULAR AND CELLULAR ENDOCRINOLOGY 80(1-3):21-31 LORENCE MC; NAVILLE D; GRAHAMLORENCE SE; MACK SO; MURRY BA; TRANT JM; MASON JI 3-BETA-HYDROXYSTEROID DEHYDROGENASE DELTA-5-]4-ISOMERASE EXPRESSION IN RAT AND CHARACTERIZATION OF THE TESTIS ISOFORM	33	3
5808	8	7726 1991 MOLECULAR MICROBIOLOGY 5(9):2099-2105 OKEEFE DP; HARDER PA OCCURRENCE AND BIOLOGICAL FUNCTION OF CYTOCHROME-P450 MONOOXYGENASES IN THE ACTINOMYCETES	32	3
5809	1	7745 1991 NEW ENGLAND JOURNAL OF MEDICINE 324(6):364-369 HALLER RG; LEWIS SF GLUCOSE-INDUCED EXERTIONAL FATIGUE IN MUSCLE PHOSPHOFRUCTOKINASE DEFICIENCY	33	3
5810	12	7771 1991 PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS 42(3):171-175 HASUNUMA K; TERANO T; TAMURA Y; YOSHIDA S FORMATION OF EPOXYEICOSATRIENOIC ACIDS FROM ARACHIDONIC-ACID BY CULTURED RAT AORTIC SMOOTH-MUSCLE CELL MICROSOMES	11	3
5811	10	7775 1991 REPRODUCTIVE TOXICOLOGY 5(6):473-480 LEE QP; YANG HYL; NAMKUNG MJ; JUCHAU MR CAMP-DEPENDENT REGULATION OF P450-CATALYZED DEALKYLATION IN RAT CONCEPTAL TISSUES	8	3
5812	19	7781 1991 SEMINARS IN NEPHROLOGY 11(2):148-155 HIRT DL; JACOBSON HR FUNCTIONAL-EFFECTS OF CYTOCHROME-P450 ARACHIDONATE METABOLITES IN THE KIDNEY	10	3
5813	2	7793 1991 TOXICOLOGY AND APPLIED PHARMACOLOGY 111(1):132-144 CHEN ZY; EATON DL DIFFERENTIAL REGULATION OF CYTOCHROME(S) P450 2B1/2 BY PHENOBARBITAL IN HEPATIC HYPERPLASTIC NODULES INDUCED BY AFLATOXIN-B1 OR DIETHYLNITROSAMINE PLUS 2-ACETYLAMINOFLUORENE IN MALE F344 RATS	13	3
5814	6	7797 1991 TRENDS IN PHARMACOLOGICAL SCIENCES 12(8):281-283 GUENGERICH FP MOLECULAR ADVANCES FOR THE CYTOCHROME-P-450 SUPERFAMILY	7	3
5815	9	7803 1991 XENOBIOTICA 21(4):461-471 PESONEN M; ANDERSSON T CHARACTERIZATION AND INDUCTION OF XENOBIOTIC METABOLIZING ENZYME-ACTIVITIES IN A PRIMARY CULTURE OF RAINBOW-TROUT HEPATOCYTES	48	3
5816	10	7811 1991 XENOBIOTICA 21(9):1091-1106 JAUREGUI HO; NG SF; GANN KL; WAXMAN DJ XENOBIOTIC INDUCTION OF P-450 PB-4 (IIB1) AND P-450C (IA1) AND ASSOCIATED MONOOXYGENASE ACTIVITIES IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	34	3
5817	2	7815 1991 YEAST 7(6):627-630 TURI TG; KALB VF; LOPER JC CYTOCHROME-P450 LANOSTEROL 14-ALPHA-DEMETHYLASE (ERG11) AND MANGANESE SUPEROXIDE-DISMUTASE (SOD1) ARE ADJACENT GENES IN SACCHAROMYCES-CEREVISIAE	5	3
5818	12	7816 1992 ACS SYMPOSIUM SERIES 505():16-30 SCOTT JG; WHEELOCK GD CHARACTERIZATION OF A CYTOCHROME-P450 RESPONSIBLE FOR PYRETHROID RESISTANCE IN THE HOUSEFLY	5	3
5819	15	7866 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 295(1):126-131 PALIN MF; BERTHIAUME L; LEHOUX JG; WATERMAN MR; SYGUSCH J DIRECT EXPRESSION OF MATURE BOVINE ADRENODOXIN IN ESCHERICHIA- COLI	11	3
5820	13	7876 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(1):96-104 HAMILTON JW; BEMENT WJ; SINCLAIR PR; SINCLAIR JF; ALCEDO JA; WETTERHAHN KE INHIBITION OF PROTEIN-SYNTHESIS INCREASES THE TRANSCRIPTION OF THE PHENOBARBITAL-INDUCIBLE CYP2H1-GENE AND CYP2H2-GENE IN CHICK-EMBRYO HEPATOCYTES	17	3
5821	6	7877 1992 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 298(1):105-113 CLEJAN LA; CEDERBAUM AI STRUCTURAL DETERMINANTS FOR ALCOHOL SUBSTRATES TO BE OXIDIZED TO FORMALDEHYDE BY RAT-LIVER MICROSOMES	8	3
5822	3	7914 1992 BIOCHEMICAL PHARMACOLOGY 43(9):1907-1910 NAKURA H; ITOH S; KUSANO H; ISHIZONE H; IMAOKA S; FUNAE Y; YOKOI T; KAMATAKI T DECREASE IN THE CONTENT OF CYTOCHROME P450IIE BY FASTING IN LIVER-MICROSOMES OF HOUSE MUSK SHREW (SUNCUS-MURINUS)	11	3
5823	11	7920 1992 BIOCHEMICAL PHARMACOLOGY 44(1):51-58 NEMOTO N; SAKURAI J ALTERED REGULATION OF CYP1A-1 GENE-EXPRESSION DURING CULTIVATION OF MOUSE HEPATOCYTES IN PRIMARY CULTURE	11	3
5824	12	7922 1992 BIOCHEMICAL PHARMACOLOGY 44(2):251-259 WALTON MI; WOLF CR; WORKMAN P THE ROLE OF CYTOCHROME-P450 AND CYTOCHROME-P450 REDUCTASE IN THE REDUCTIVE BIOACTIVATION OF THE NOVEL BENZOTRIAZINE DI-N- OXIDE HYPOXIC CYTOTOXIN 3-AMINO-1,2,4-BENZOTRIAZINE-1,4-DIOXIDE (SR-4233, WIN-59075) BY MOUSE-LIVER	53	3
5825	10	7982 1992 BRITISH JOURNAL OF CLINICAL PHARMACOLOGY 34(5):415-420 HAKKOLA J; MAENPAA J; MAYER RT; PARK SS; GELBOIN HV; PELKONEN O 7-ALKOXYQUINOLINE O-DEALKYLATION BY MICROSOMES FROM HUMAN LIVER AND PLACENTA	5	3
5826	3	7983 1992 BRITISH JOURNAL OF INDUSTRIAL MEDICINE 49(2):104-112 WANG RS; NAKAJIMA T EFFECTS OF ETHANOL AND PHENOBARBITAL TREATMENTS ON THE PHARMACOKINETICS OF TOLUENE IN RATS	13	3
5827	3	7997 1992 CARCINOGENESIS 13(1):95-100 KENSLER TW; GROOPMAN JD; EATON DL; CURPHEY TJ; ROEBUCK BD POTENT INHIBITION OF AFLATOXIN-INDUCED HEPATIC TUMORIGENESIS BY THE MONOFUNCTIONAL ENZYME INDUCER 1,2-DITHIOLE-3-THIONE	60	3
5828	13	8003 1992 CARCINOGENESIS 13(7):1199-1207 SCHARPING CE; MCMANUS ME; HOLDER GM NADPH-SUPPORTED AND ARACHIDONIC ACID-SUPPORTED METABOLISM OF THE ENANTIOMERS OF TRANS-7,8-DIHYDROBENZO[A]PYRENE-7,8-DIOL BY HUMAN LIVER MICROSOMAL SAMPLES	11	3
5829	11	8061 1992 DRUG METABOLISM AND DISPOSITION 20(6):792-796 DING XX; PENG HM; PERNECKY SJ; DAVIS CJ; COON MJ INDUCTION OF P-450 CYTOCHROME-2E2, CYTOCHROME-1A1, AND CYTOCHROME-1A2 BY IMIDAZOLE IN NEONATAL RABBITS	7	3
5830	6	8141 1992 INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS 30(12):555-570 ALBENGRES E; TILLEMENT JP CYCLOSPORINE AND KETOCONAZOLE, DRUG-INTERACTION OR THERAPEUTIC ASSOCIATION	19	3
5831	10	8153 1992 JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 24(2):235-241 RAUCHOVA H; BATTINO M; FATO R; LENAZ G; DRAHOTA Z COENZYME-Q-POOL FUNCTION IN GLYCEROL-3-PHOSPHATE OXIDATION IN HAMSTER BROWN ADIPOSE-TISSUE MITOCHONDRIA	11	3
5832	6	8169 1992 JOURNAL OF BIOLOGICAL CHEMISTRY 267(16):11120-11125 TA DT; VICKERY LE CLONING, SEQUENCING, AND OVEREXPRESSION OF A [2FE-2S] FERREDOXIN GENE FROM ESCHERICHIA-COLI	66	3
5833	4	8193 1992 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 582(1-2):232-235 OESCH F; WAGNER H; PLATT KL; ARAND M IMPROVED SAMPLE PREPARATION FOR THE TESTOSTERONE HYDROXYLATION ASSAY USING DISPOSABLE EXTRACTION COLUMNS	18	3
5834	12	8194 1992 JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS 583(2):231-235 OLIW EH ENANTIOSELECTIVE SEPARATION OF SOME POLYUNSATURATED EPOXY FATTY-ACIDS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY ON A CELLULOSE PHENYLCARBAMATE (CHIRALCEL OC) STATIONARY PHASE	5	3
5835	7	8205 1992 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 40(1):73-82 FUKUI Y; YAMAMOTO A; MASAKI R; MIYAUCHI K; TASHIRO Y QUANTITATIVE IMMUNOCYTOCHEMICAL ANALYSIS OF THE INDUCTION OF CYTOCHROME-P450IIB IN RAT HEPATOCYTES	14	3
5836	10	8214 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 261(1):373-380 MURRAY M; CANTRILL E; MEHTA I; FARRELL GC IMPAIRED EXPRESSION OF MICROSOMAL CYTOCHROME-P450-2C11 IN CHOLINE-DEFICIENT RAT-LIVER DURING THE DEVELOPMENT OF CIRRHOSIS	15	3
5837	7	8224 1992 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 263(2):780-786 FUNCKBRENTANO C; THOMAS G; JACQZAIGRAIN E; POIRIER JM; SIMON T; BEREZIAT G; JAILLON P POLYMORPHISM OF DEXTROMETHORPHAN METABOLISM - RELATIONSHIPS BETWEEN PHENOTYPE, GENOTYPE AND RESPONSE TO THE ADMINISTRATION OF ENCAINIDE IN HUMANS	31	3
5838	10	8236 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 43(8):931-935 WATERMAN MR; KAGAWA N; ZANGER UM; MOMOI K; LUND J; SIMPSON ER COMPARISON OF CAMP-RESPONSIVE DNA-SEQUENCES AND THEIR BINDING- PROTEINS ASSOCIATED WITH EXPRESSION OF THE BOVINE CYP17-GENES AND CYP11A-GENES AND HUMAN CYP21B-GENES	13	3
5839	11	8240 1992 JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY 43(8):1037-1043 HANIOKA N; GONZALEZ FJ; LINDBERG NA; LIU G; KORZEKWA KR CHIMERIC CDNA EXPRESSION AND SITE DIRECTED MUTAGENESIS STUDIES OF CYTOCHROME-P450S CYP2A1 AND CYP2A2	5	3
5840	2	8254 1992 MAMMALIAN GENOME 3(1):17-22 RAMESH V; CHENG SV; KOZAK CA; HERRON BJ; SHIH VE; TAYLOR BA; GUSELLA JF MAPPING OF ORNITHINE AMINOTRANSFERASE GENE-SEQUENCES TO MOUSE CHROMOSOME-7, CHROMOSOME-X, AND CHROMOSOME-3	10	3
5841	13	8279 1992 MOLECULAR PHARMACOLOGY 42(4):695-702 KUMAGAI Y; LIN LY; PHILPOT RM; YAMADA H; OGURI K; YOSHIMURA H; CHO AK REGIOCHEMICAL DIFFERENCES IN CYTOCHROME-P450 ISOZYMES RESPONSIBLE FOR THE OXIDATION OF METHYLENEDIOXYPHENYL GROUPS BY RABBIT LIVER	9	3
5842	4	8321 1992 RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY 76(1):43-51 ANTIGNAC E; FUKUHARA M IDENTIFICATION OF A CONSTITUTIVE FORM OF CYTOCHROME-P-450 WITH HIGH-ACTIVITY TOWARDS MACROLIDE ANTIBIOTICS IN SYRIAN GOLDEN- HAMSTER LIVER	5	3
5843	2	8322 1992 RESPIRATION 59(4):201-210 AIDA S; TAKAHASHI Y; SUZUKI E; KIMULA Y; ITO Y; MIURA T ELECTRON-MICROSCOPIC EVIDENCE FOR CYTOCHROME-P-450 IN CLARA CELLS AND TYPE-I PNEUMOCYTES OF THE RAT LUNG	6	3
5844	6	8340 1992 TOXICOLOGY LETTERS 62(2-3):191-199 ISCAN M; COBAN T; ISCAN M COMBINED EFFECT OF CADMIUM AND NICKEL ON RAT HEPATIC MONOOXYGENASES - POSSIBLE STIMULATION OF CERTAIN CYTOCHROME-P- 450 ISOZYMES	7	3
5845	2	8362 1993 ADVERSE DRUG REACTIONS AND TOXICOLOGICAL REVIEWS 12(1):5-34 MONRO A HOW USEFUL ARE CHRONIC (LIFE-SPAN) TOXICOLOGY STUDIES IN RODENTS IN IDENTIFYING PHARMACEUTICALS THAT POSE A CARCINOGENIC RISK TO HUMANS	18	3
5846	8	8371 1993 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 8(6):597-604 MILES PR; BOWMAN L; MILLER MR ALTERATIONS IN THE PULMONARY MICROSOMAL CYTOCHROME-P-450 SYSTEM AFTER EXPOSURE OF RATS TO SILICA	10	3
5847	11	8419 1993 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 307(2):369-378 WEBER GF; WAXMAN DJ DENITROSATION OF THE ANTICANCER DRUG 1,3-BIS(2-CHLOROETHYL)-1- NITROSOUREA CATALYZED BY MICROSOMAL GLUTATHIONE-S-TRANSFERASE AND CYTOCHROME-P450 MONOOXYGENASES	15	3
5848	11	8430 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 191(1):282-288 HOMMA T; ZHANG JY; SHIMIZU T; PRAKASH C; BLAIR IA; HARRIS RC CYCLOOXYGENASE-DERIVED METABOLITES OF 8,9-EPOXYEICOSATRIENOIC ACID ARE POTENT MITOGENS FOR CULTURED RAT GLOMERULAR MESANGIAL CELLS	6	3
5849	4	8437 1993 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 196(3):1255-1260 OBIKA K; TOMURA D; FUKAMIZU A; SHOUN H EXPRESSION OF THE FUNGAL CYTOCHROME-P-450NOR CDNA IN ESCHERICHIA-COLI	10	3
5850	10	8447 1993 BIOCHEMICAL JOURNAL 292():309-310 MURRAY BP; EDWARDS RJ; DAVIES DS; BOOBIS AR CONSERVATION OF A FUNCTIONALLY IMPORTANT SURFACE REGION BETWEEN 2 FAMILIES OF THE CYTOCHROME-P-450 SUPERFAMILY	4	3
5851	10	8461 1993 BIOCHEMICAL PHARMACOLOGY 45(6):1323-1331 BORNHEIM LM; EVERHART ET; LI JM; CORREIA MA CHARACTERIZATION OF CANNABIDIOL-MEDIATED CYTOCHROME-P450 INACTIVATION	12	3
5852	2	8465 1993 BIOCHEMICAL PHARMACOLOGY 45(8):1721-1724 YOKOYAMA H; HORIE T; AWAZU S LIPID-PEROXIDATION IN RAT-LIVER MICROSOMES DURING NAPROXEN METABOLISM	8	3
5853	6	8490 1993 BIOCHEMISTRY 32(15):4014-4021 MAHY JP; GASPARD S; MANSUY D PHENYLHYDRAZONES AS NEW GOOD SUBSTRATES FOR THE DIOXYGENASE AND PEROXIDASE REACTIONS OF PROSTAGLANDIN SYNTHASE - FORMATION OF IRON(III)-SIGMA-PHENYL COMPLEXES	9	3
5854	4	8494 1993 BIOCHEMISTRY 32(34):8856-8862 PFEIL W; NOLTING BO; JUNG C APOCYTOCHROME-P450CAM IS A NATIVE PROTEIN WITH SOME INTERMEDIATE-LIKE PROPERTIES	22	3
5855	9	8500 1993 BIOCHEMISTRY 32(47):12841-12849 SWANSON HI; TULLIS K; DENISON MS BINDING OF TRANSFORMED AH RECEPTOR COMPLEX TO A DIOXIN- RESPONSIVE TRANSCRIPTIONAL ENHANCER - EVIDENCE FOR 2 DISTINCT HETEROMERIC DNA-BINDING FORMS	24	3
5856	6	8503 1993 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 31(6):1071-1080 ARCHAKOV AI; DEGTYARENKO KN STRUCTURAL CLASSIFICATION OF THE P450 SUPERFAMILY BASED ON CONSENSUS SEQUENCE COMPARISON	3	3
5857	2	8517 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1173(2):165-171 ITOH K; KIMURA T; YOKOI T; ITOH S; KAMATAKI T RAT-LIVER FLAVIN-CONTAINING MONOOXYGENASE (FMO) - CDNA CLONING AND EXPRESSION IN YEAST	36	3
5858	6	8519 1993 BIOCHIMICA ET BIOPHYSICA ACTA 1203(2):199-204 BRIAND J; JULISTIONO H; BEAUNE P; FLINOIS JP; DEWAZIERS I; LEROUX JP PRESENCE OF PROTEINS RECOGNIZED BY MAMMALIAN CYTOCHROME-P-450 ANTIBODIES IN EUGLENA-GRACILIS	12	3
5859	3	8542 1993 CANCER RESEARCH 53(19):4608-4612 TOUSSAINT C; ALBIN N; MASSAAD L; GRUNENWALD D; PARISE O; MORIZET J; GOUYETTE A; CHABOT GG MAIN DRUG-METABOLIZING AND CARCINOGEN-METABOLIZING ENZYME- SYSTEMS IN HUMAN NONSMALL CELL LUNG-CANCER AND PERITUMORAL TISSUES	21	3
5860	7	8553 1993 CARCINOGENESIS 14(8):1683-1688 KOMORI M; KITAMURA R; FUKUTA H; INOUE H; BABA H; YOSHIKAWA K; KAMATAKI T TRANSGENIC DROSOPHILA CARRYING MAMMALIAN CYTOCHROME-P-4501A1 - AN APPLICATION TO TOXICOLOGY TESTING	8	3
5861	6	8555 1993 CARCINOGENESIS 14(10):2115-2118 JENSEN KG; ONFELT A; POULSEN HE; DOEHMER J; LOFT S EFFECTS OF BENZO[A]PYRENE AND (PLUS-OR-MINUS)-TRANS-7,8- DIHYDROXY-7,8-DIHYDROBENZO[A]PYRENE ON MITOSIS IN CHINESE- HAMSTER V79 CELLS WITH STABLE EXPRESSION OF RAT CYTOCHROME P4501A1 OR 1A2	19	3
5862	9	8581 1993 CYTOTECHNOLOGY 12(1-3):357-366 DOEHMER J; GOEPTAR AR; VERMEULEN NPE CYTOCHROMES P450 AND DRUG-RESISTANCE	5	3
5863	8	8613 1993 EUROPEAN JOURNAL OF BIOCHEMISTRY 213(1):211-216 ELTIS LD; KARLSON U; TIMMIS KN PURIFICATION AND CHARACTERIZATION OF CYTOCHROME-P450(RR1) FROM RHODOCOCCUS-RHODOCHROUS	17	3
5864	8	8714 1993 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 41(6):877-885 VOIGT JM; GUENGERICH FP; BARON J LOCALIZATION AND INDUCTION OF CYTOCHROME-P450 1A1 AND ARYL- HYDROCARBON HYDROXYLASE-ACTIVITY IN RAT NASAL-MUCOSA	24	3
5865	1	8717 1993 JOURNAL OF LABORATORY AND CLINICAL MEDICINE 121(3):372-374 SERHAN CN CELL-CELL INTERACTIONS IN THE GENERATION OF EICOSANOIDS - CHARTING THE ROUTES AND PRODUCTS OF TRANSCELLULAR BIOSYNTHESIS	12	3
5866	9	8722 1993 JOURNAL OF NEUROCHEMISTRY 60(4):1467-1474 KURZ GM; WIESINGER H; HAMPRECHT B PURIFICATION OF CYTOSOLIC MALIC ENZYME FROM BOVINE BRAIN, GENERATION OF MONOCLONAL-ANTIBODIES, AND IMMUNOCYTOCHEMICAL LOCALIZATION OF THE ENZYME IN GLIAL-CELLS OF NEURAL PRIMARY CULTURES	54	3
5867	6	8724 1993 JOURNAL OF NUTRITION 123(2):216-224 MCINTOSH MK; GOLDFARB AH; CURTIS LN; COTE PS VITAMIN-E ALTERS HEPATIC ANTIOXIDANT ENZYMES IN RATS TREATED WITH DEHYDROEPIANDROSTERONE (DHEA)	24	3
5868	5	8733 1993 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 265(3):1261-1266 OWENS SM; GUNNELL M; LAURENZANA EM; VALENTINE JL DOSE-DEPENDENT AND TIME-DEPENDENT CHANGES IN PHENCYCLIDINE METABOLITE COVALENT BINDING IN RATS AND THE POSSIBLE ROLE OF CYP2D1	16	3
5869	9	8749 1993 JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 3(8):1496-1500 TAKAHASHI K; HARRIS RC; CAPDEVILA JH; KARARA A; MAKITA K; JACOBSON HR; MUNGER KA; BADR KF INDUCTION OF RENAL ARACHIDONATE CYTOCHROME-P-450 EPOXYGENASE AFTER UNINEPHRECTOMY - COUNTERREGULATION OF HYPERFILTRATION	10	3
5870	11	8754 1993 JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH 40(2-3):177-194 SIDHU JS; KAVANAGH TJ; REILLY MT; OMIECINSKI CJ DIRECT DETERMINATION OF FUNCTIONAL-ACTIVITY OF CYTOCHROME-P- 4501A1 AND NADPH DT-DIAPHORASE IN HEPATOMA-CELL LINES USING NONINVASIVE SCANNING LASER CYTOMETRY	14	3
5871	5	8760 1993 LIFE SCIENCES 52(21):1709-1716 RAO MS; IDE H; ALVARES K; SUBBARAO V; REDDY JK; HECHTER O; YELDANDI AV COMPARATIVE EFFECTS OF DEHYDROEPIANDROSTERONE AND RELATED STEROIDS ON PEROXISOME PROLIFERATION IN RAT-LIVER	12	3
5872	9	8768 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 91(1-2):201-209 OERTLE M; MULLER J 2 TYPES OF CYTOCHROME-P-45011-BETA IN RAT ADRENALS - SEPARATE REGULATION OF GENE-EXPRESSION	27	3
5873	4	8770 1993 MOLECULAR AND CELLULAR ENDOCRINOLOGY 94(2):R9-R13 HOLLAND OB; MATHIS JM; BIRD IM; RAINEY WE ANGIOTENSIN INCREASES ALDOSTERONE SYNTHASE MESSENGER-RNA LEVELS IN HUMAN NCI-H295 CELLS	23	3
5874	5	8806 1993 PHARMACOLOGICAL RESEARCH 28(3):243-248 HORSMANS Y; DESAGER JP; VANDENBERGE V; ABRASSART M; HARVENGT C EFFECTS OF SIMVASTATIN AND PRAVASTATIN ON 6-BETA- HYDROXYCORTISOL EXCRETION, A POTENTIAL MARKER OF CYTOCHROME-P- 450-3A	18	3
5875	3	8811 1993 PHARMACOLOGY & THERAPEUTICS 58(1):67-91 QUIROGA J; PRIETO J LIVER CYTOPROTECTION BY PROSTAGLANDINS	67	3
5876	7	8828 1993 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 90(9):4047-4051 KERSTING U; KERSTING D; SPRING KR KETOCONAZOLE ACTIVATES CL- CONDUCTANCE AND BLOCKS CL- AND FLUID ABSORPTION BY CULTURED CYSTIC-FIBROSIS (CFPAC-1) CELLS	24	3
5877	9	8835 1993 PROGRESS IN LIPID RESEARCH 32(4):357-416 MERCER EI INHIBITORS OF STEROL BIOSYNTHESIS AND THEIR APPLICATIONS	45	3
5878	13	8848 1993 THERAPIE 48(6):521-526 BEAUNE P HUMAN CYTOCHROMES P450 - APPLICATIONS IN PHARMACOLOGY	13	3
5879	10	8865 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 120(2):298-307 KOCAREK TA; SCHUETZ EG; GUZELIAN PS REGULATION OF PHENOBARBITAL-INDUCIBLE CYTOCHROME-P450 2B1/2 MESSENGER-RNA BY LOVASTATIN AND OXYSTEROLS IN PRIMARY CULTURES OF ADULT-RAT HEPATOCYTES	25	3
5880	10	8866 1993 TOXICOLOGY AND APPLIED PHARMACOLOGY 123(1):34-42 TAI HL; MCREYNOLDS JH; GOLDSTEIN JA; EUGSTER HP; SENGSTAG C; ALWORTH WL; OLSON JR CYTOCHROME-P4501A1 MEDIATES THE METABOLISM OF 2,3,7,8- TETRACHLORODIBENZOFURAN IN THE RAT AND HUMAN	20	3
5881	33	8885 1994 ADVANCES IN ENZYMOLOGY AND RELATED AREAS OF MOLECULAR BIOLOGY, VOL 68 68():37-66 WATERMAN MR HETEROLOGOUS EXPRESSION OF MAMMALIAN P450 ENZYMES	8	3
5882	19	8890 1994 AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 11(4):386-396 PAIRON JC; TRABELSI N; BUARD A; FLEURYFEITH J; BACHELET CM; PORON F; BEAUNE P; BROCHARD P; LAURENT P CELL LOCALIZATION AND REGULATION OF EXPRESSION OF CYTOCHROME- P450 1A1 AND 2B1 IN RAT LUNG AFTER INDUCTION WITH 3- METHYLCHOLANTHRENE USING MESSENGER-RNA HYBRIDIZATION AND IMMUNOHISTOCHEMISTRY	11	3
5883	2	8892 1994 ANAESTHESIA 49(3):188-191 PARK GR; PICHARD L; TINEL M; LARROQUE C; ELSTON A; DOMERQUE J; DEXIONNE B; MAUREL P WHAT CHANGES DRUG-METABOLISM IN CRITICALLY ILL PATIENTS - 2 PRELIMINARY STUDIES IN ISOLATED HUMAN HEPATOCYTES	17	3
5884	4	8894 1994 ANALYTICAL BIOCHEMISTRY 216(1):176-187 DIETZE EC; KUWANO E; HAMMOCK BD SPECTROPHOTOMETRIC SUBSTRATES FOR CYTOSOLIC EPOXIDE HYDROLASE	15	3
5885	12	8895 1994 ANALYTICAL BIOCHEMISTRY 218(1):80-86 BONFILS C; DAUJAT M; CHEVRON MP; DALETBELUCHE I ELECTROTRANSFER OF MICROSOMAL CYTOCHROME-P450 AFTER ISOELECTRIC-FOCUSING (IEF BLOTS) - RESOLUTION OF HUMAN 2A- ISOENZYMES AND 3A-ISOZYMES	7	3
5886	10	8908 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 308(2):380-386 WU FF; VERGERES G; WASKELL L KINETICS OF THE REDUCTION OF CYTOCHROME B(5) WITH MUTATIONS IN ITS MEMBRANE-BINDING DOMAIN	7	3
5887	4	8917 1994 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 311(2):369-377 RETTIE AE; LAWTON MP; SADEQUE AJM; MEIER GP; PHILPOT RM PROCHIRAL SULFOXIDATION AS A PROBE FOR MULTIPLE FORMS OF THE MICROSOMAL FLAVIN-CONTAINING MONOOXYGENASE - STUDIES WITH RABBIT FMO1, FMO2, FMO3, AND FMO5 EXPRESSED IN ESCHERICHIA-COLI	19	3
5888	3	8942 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 201(1):373-378 LEFEVER MR; WACKETT LP OXIDATION OF LOW-MOLECULAR-WEIGHT CHLOROALKANES BY CYTOCHROME P450(CAM)	8	3
5889	4	8952 1994 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 203(3):1745-1749 GONVINDARAJ S; LI HY; POULOS TL FLAVIN SUPPORTED FATTY-ACID OXIDATION BY THE HEME DOMAIN OF BACILLUS-MEGATERIUM CYTOCHROME-P450(BM-3)	3	3
5890	14	8996 1994 BIOCHEMISTRY 33(43):12920-12929 HILDEBRANDT P; HEIBEL G; ANZENBACHER P; LANGE R; KRUGER V; STIER A CONFORMATIONAL-ANALYSIS OF MITOCHONDRIAL AND MICROSOMAL CYTOCHROME-P-450 BY RESONANCE RAMAN-SPECTROSCOPY	17	3
5891	6	9006 1994 BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1217(2):229-231 SAKUMA T; TAKAI M; YOKOI T; KAMATAKI T MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF HAMSTER CYP2E1	7	3
5892	11	9018 1994 BIOLOGICAL & PHARMACEUTICAL BULLETIN 17(6):803-807 NARIMATSU S; MASUBUCHI Y; HOSOKAWA S; OHMORI S; KITADA M; SUZUKI T INVOLVEMENT OF A CYTOCHROME-P4502D SUBFAMILY IN HUMAN LIVER MICROSOMAL BUNITROLOL 4-HYDROXYLATION	14	3
5893	8	9026 1994 CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES 51(2):315-320 GOKSOYR A; BJORNEVIK M; MAAGE A EFFECTS OF DIETARY IRON CONCENTRATIONS ON THE CYTOCHROME-P450 SYSTEM OF ATLANTIC SALMON (SALMO-SALAR)	9	3
5894	15	9044 1994 CARCINOGENESIS 15(12):2835-2840 CHALOUPKA K; SANTOSTEFANO M; GOLDFARB IS; LIU G; MYERS MJ; TSYROLV IB; GELBOIN HV; KRISHNAN V; SAFE S ARYL-HYDROCARBON (AH) RECEPTOR-INDEPENDENT INDUCTION OF CYP1A2 GENE-EXPRESSION BY ACENAPHTHYLENE AND RELATED-COMPOUNDS IN B6C3F1 MICE	25	3
5895	10	9060 1994 CLINICAL PHARMACOLOGY & THERAPEUTICS 56(3):253-260 TURGEON DK; LEICHTMAN AB; LOWN KS; NORMOLLE DP; DEEB GM; MERION RM; WATKINS PB P450 3A ACTIVITY AND CYCLOSPORINE DOSING IN KIDNEY AND HEART- TRANSPLANT RECIPIENTS	37	3
5896	8	9079 1994 DNA AND CELL BIOLOGY 13(11):1087-1098 GIVENS CR; ZHANG PL; BAIR SR; MELLON SH TRANSCRIPTIONAL REGULATION OF RAT CYTOCHROME P450C17 EXPRESSION IN MOUSE LEYDIG MA-10 AND ADRENAL Y-1 CELLS - IDENTIFICATION OF A SINGLE PROTEIN THAT MEDIATES BOTH BASAL AND CAMP-INDUCED ACTIVITIES	30	3
5897	17	9084 1994 DRUG METABOLISM AND DISPOSITION 22(2):248-253 FORKERT PG; REDZA ZM; MANGOS S; PARK SS; TAM SP INDUCTION AND REGULATION OF CYP2E1 IN MURINE LIVER AFTER ACUTE AND CHRONIC ACETONE ADMINISTRATION	29	3
5898	15	9085 1994 DRUG METABOLISM AND DISPOSITION 22(2):331-337 NAMKUNG MJ; YANG HYL; JUCHAU MR CYTOCHROME P-450-DEPENDENT BIOTRANSFORMATION OF 2- ACETYLAMINOFLUORENE IN CELL-FREE PREPARATIONS OF HUMAN EMBRYONIC HEPATIC, ADRENAL, RENAL, PULMONARY, AND CARDIAC TISSUES	11	3
5899	13	9088 1994 DRUG METABOLISM AND DISPOSITION 22(4):607-615 KITAREEWAN S; WALZ FG GENETIC AND DEVELOPMENTAL DIVERSITY OF HEPATIC CYTOCHROMES-P450 - WARFARIN AND PROGESTERONE METABOLISM BY HEPATIC MICROSOMES FROM 4 INBRED STRAINS OF RAT	5	3
5900	3	9109 1994 EUROPEAN JOURNAL OF BIOCHEMISTRY 220(3):729-737 VIEIRA LM; KAPLAN JC; KAHN A; LEROUX A HETEROGENEITY OF THE RAT NADH-CYTOCHROME-B(5)-REDUCTASE TRANSCRIPTS RESULTING FROM MULTIPLE ALTERNATIVE FIRST EXONS	7	3

#	Cited nodes	Nodes / Authors	GCS	LCS
5901	25	9113 1994 EUROPEAN JOURNAL OF BIOCHEMISTRY 223(3):947-956 PEYRONNEAU MA; DELAFORGE M; RIVIERE R; RENAUD JP; MANSUY D HIGH-AFFINITY OF ERGOPEPTIDES FOR CYTOCHROMES P450 3A - IMPORTANCE OF THEIR PEPTIDE MOIETY FOR P450 RECOGNITION AND HYDROXYLATION OF BROMOCRIPTINE	26	3
5902	2	9126 1994 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS 19(2):119-124 GUITTON J; SOUILLET G; RIVIERE JL; GERARD F; GUILLUY R; BRAZIER JL ACTION OF METHOTREXATE ON CYTOCHROME-P-450 MONOOXYGENASES IN RATS - STUDY PERFORMED WITH [C-13]-AMINOPYRINE MICRO BREATH TEST	6	3
5903	3	9142 1994 FOOD AND CHEMICAL TOXICOLOGY 32(9):819-& BEAMAND JA; PRICE RJ; BLOWERS SD; WIELD PT; CUNNINGHAME ME; LAKE BG USE OF PRECISION-CUT LIVER SLICES FOR STUDIES OF UNSCHEDULED DNA-SYNTHESIS	15	3
5904	6	9147 1994 FREE RADICAL RESEARCH 20(1):51-60 REINKE LA; BAILEY SM; RAU JM; MCCAY PB OXYGEN RADICAL FORMATION IN WELL-WASHED RAT-LIVER MICROSOMES - SPIN-TRAPPING STUDIES	14	3
5905	12	9149 1994 FUNDAMENTAL AND APPLIED TOXICOLOGY 22(4):549-560 MOORTHY B; SRIRAM P; RANDERATH K CHEMICAL STRUCTURE-DEPENDENT AND TIME-DEPENDENT EFFECTS OF POLYCYCLIC AROMATIC HYDROCARBON-TYPE INDUCERS ON RAT-LIVER CYTOCHROME-P450, DNA-ADDUCTS, AND I-COMPOUNDS	17	3
5906	8	9169 1994 JAPANESE JOURNAL OF HUMAN GENETICS 39(3):337-343 INOUE K; INAZAWA J; SUZUKI Y; SHIMADA T; YAMAZAKI H; GUENGERICH FP; ABE T FLUORESCENCE IN-SITU HYBRIDIZATION ANALYSIS OF CHROMOSOMAL LOCALIZATION OF 3 HUMAN CYTOCHROME-P450-2C GENES (CYP2C8, 2C9, AND 2C10) AT 10Q24.1	5	3
5907	10	9187 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(11):8001-8006 MIURA S; ICHIKAWA Y INTERACTION OF NADPH-ADRENOFERREDOXIN REDUCTASE WITH NADP(+) AND ADRENOFERREDOXIN - EQUILIBRIUM AND DYNAMIC PROPERTIES INVESTIGATED BY PROTON NUCLEAR-MAGNETIC-RESONANCE	3	3
5908	4	9204 1994 JOURNAL OF BIOLOGICAL CHEMISTRY 269(42):26083-26091 FREY C; NARAYANAN K; MCMILLAN K; SPACK L; GROSS SS; MASTERS BS; GRIFFITH OW L-THIOCITRULLINE - A STEREOSPECIFIC, HEME-BINDING INHIBITOR OF NITRIC-OXIDE SYNTHASES	70	3
5909	18	9252 1994 JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS 270(1):407-413 WU DF; CEDERBAUM AI CHARACTERIZATION OF PYRAZOLE AND 4-METHYLPYRAZOLE INDUCTION OF CYTOCHROME P4502E1 IN RAT-KIDNEY	12	3
5910	17	9273 1994 JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY 32(6):631-681 LIEBER CS MECHANISMS OF ETHANOL-DRUG-NUTRITION INTERACTIONS	44	3
5911	3	9304 1994 MOLECULAR PHARMACOLOGY 46(1):79-87 SHAW PM; WEISS MC; ADESNIK M HEPATOCYTE NUCLEAR FACTOR-3 IS A MAJOR DETERMINANT OF CYP2C6 PROMOTER ACTIVITY IN HEPATOMA-CELLS	15	3
5912	6	9326 1994 PHARMACOGENETICS 4(4):199-207 FLEMING CM; PERSAD R; KAISARY A; SMITH P; ADEDOYIN A; PORTER J; WILKINSON GR; BRANCH RA LOW ACTIVITY OF DAPSONE N-HYDROXYLATION AS A SUSCEPTIBILITY RISK FACTOR IN AGGRESSIVE BLADDER-CANCER	17	3
5913	1	9383 1994 TRANSPLANTATION PROCEEDINGS 26(5):2902-2907 WOLF A; CLEMANN N; FRIEAUFF W; RYFFEL B; CORDIER A ROLE OF REACTIVE OXYGEN FORMATION IN THE CYCLOSPORINE-A- MEDIATED IMPAIRMENT OF RENAL FUNCTIONS	25	3
5914	1	9384 1994 TRANSPLANTATION PROCEEDINGS 26(5):2912-2914 WOLF A; TRENDELENBURG CF; DIEZFERNANDEZ C; PRIETO P; CORDIER A ROLE OF GLUTATHIONE IN CYCLOSPORINE-A IN-VITRO HEPATOTOXICITY	17	3
5915	10	9391 1994 XENOBIOTICA 24(8):795-803 VANIERSEL MLPS; HENDERSON CJ; WALTERS DG; PRICE RJ; WOLF CR; LAKE BG METABOLISM OF [3-C-14] COUMARIN BY HUMAN LIVER-MICROSOMES	16	3
5916	8	9393 1994 XENOBIOTICA 24(10):989-1001 DENBESTEN PJ; LEMAIRE P; LIVINGSTONE DR NADPH-DEPENDNENT, NADH-DEPENDENT AND CUMENE HYDROPEROXIDE- DEPENDENT METABOLISM OF BENZO[A]PYRENE BY PYLORIC CECA MICROSOMES OF THE SEA-STAR, ASTERIAS-RUBENS L (ECHINODERMATA, ASTEROIDEA)	7	3
5917	3	9419 1995 APPLIED AND ENVIRONMENTAL MICROBIOLOGY 61(10):3628-3632 KELLER NP; SEGNER S; BHATNAGAR D; ADAMS TH STCS, A PUTATIVE P-450 MONOOXYGENASE, IS REQUIRED FOR THE CONVERSION OF VERSICOLORIN-A TO STERIGMATOCYSTIN IN ASPERGILLUS-NIDULANS	18	3
5918	8	9468 1995 ARCHIVES OF TOXICOLOGY 69(7):491-497 WILSON MW; LAY LT; CHOW CK; TAI HH; ROBERTSON LW; GLAUERT HP ALTERED HEPATIC EICOSANOID CONCENTRATIONS IN RATS TREATED WITH THE PEROXISOME PROLIFERATORS CIPROFIBRATE AND PERFLUORODECANOIC ACID	16	3
5919	12	9472 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 211(2):497-503 GOASDUFF T; MENEZ JF; DREANO Y; BERTHOU F CYP1A2 AND 2E1 EXPRESSION IN RAT-LIVER TREATED WITH COMBINED INDUCERS (3-METHYLCHOLANTHRENE AND ETHANOL)	12	3
5920	9	9473 1995 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 212(2):433-441 ZAPHIROPOULOS PG; SKANTZ A; ELIASSON M; AHLBERG MB CYTOCHROME-P450 GENES EXPRESSED IN PORCINE OVARIES - IDENTIFICATION OF NOVEL FORMS, EVIDENCE FOR GENE CONVERSION, AND EVOLUTIONARY RELATIONSHIPS	7	3
5921	2	9486 1995 BIOCHEMICAL PHARMACOLOGY 49(4):421-440 MASER E XENOBIOTIC CARBONYL REDUCTION AND PHYSIOLOGICAL STEROID OXIDOREDUCTION - THE PLURIPOTENCY OF SEVERAL HYDROXYSTEROID DEHYDROGENASES	74	3
5922	12	9494 1995 BIOCHEMICAL PHARMACOLOGY 49(10):1443-1452 MCNAMEE JP; KIMMETT SM; MARKS GS INACTIVATION OF CHICK-EMBRYO HEPATIC CYTOCHROME-P450 1A, 2H AND 3A FOLLOWING IN OVO ADMINISTRATION OF 3,5-DIETHOXYCARBONYL-1,4- DIHYDRO-2,6-DIMETHYL-4-ETHYLPYRIDINE AND 3-[2-(2,4,6- TRIMETHYLPHENYL)THIOETHYL]-4-METHYLSYDNONE	4	3
5923	15	9501 1995 BIOCHEMICAL PHARMACOLOGY 50(9):1509-1515 GROGAN J; SHOU MG; ANDRUSIAK EA; TAMURA S; BUTERS JTM; GONZALEZ FJ; KORZEKWA KR CYTOCHROME-P450 2A1, 2E1, AND 2C9 CDNA-EXPRESSION BY INSECT CELLS AND PARTIAL-PURIFICATION USING HYDROPHOBIC CHROMATOGRAPHY	13	3
5924	12	9502 1995 BIOCHEMICAL PHARMACOLOGY 50(10):1567-1575 SMITH PB; TIANO HF; NESNOW S; BOYD MR; PHILPOT RM; LANGENBACH R 4-IPOMEANOL AND 2-AMINOANTHRACENE CYTOTOXICITY IN C3H/10T1/2 CELLS EXPRESSING RABBIT CYTOCHROME-P450 4B1	12	3
5925	13	9505 1995 BIOCHEMICAL PHARMACOLOGY 50(12):2021-2032 Simpson AECM; Brammar WJ; Pratten MK; Elcombe CR Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate	6	3
5926	10	9516 1995 BIOCHEMISTRY 34(40):12932-12936 KOBAYASHI K; MIURA S; MIKI M; ICHIKAWA Y; TAGAWA S INTERACTION OF NADPH-ADRENODOXIN REDUCTASE WITH NADP(+) AS STUDIED BY PULSE-RADIOLYSIS	6	3
5927	16	9525 1995 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1245(1):107-115 LEHNERER M; SCHULZE J; PETZOLD A; BERNHARDT R; HLAVICA P RABBIT LIVER CYTOCHROME-P-450 2B5 - HIGH-LEVEL EXPRESSION OF THE FULL-LENGTH PROTEIN IN ESCHERICHIA-COLI, PURIFICATION, AND CATALYTIC ACTIVITY	8	3
5928	6	9527 1995 BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 1258(3):234-240 ZOSMER A; RENDELL NB; TAYLOR GW; ELDER MG; SULLIVAN MHF FORMATION AND METABOLISM OF 14,15-EPOXYEICOSATRIENOIC ACID BY HUMAN REPRODUCTIVE TISSUES	6	3
5929	1	9544 1995 BRAIN 118():339-357 JACKSON MJ; SCHAEFER JA; JOHNSON MA; MORRIS AAM; TURNBULL DM; BINDOFF LA PRESENTATION AND CLINICAL INVESTIGATION OF MITOCHONDRIAL RESPIRATORY-CHAIN DISEASE - A STUDY OF 51 PATIENTS	67	3
5930	5	9551 1995 CANADIAN JOURNAL OF MICROBIOLOGY 41(6):477-488 LAUNEN L; PINTO L; WIEBE C; KIEHLMANN E; MOORE M THE OXIDATION OF PYRENE AND BENZO[A]PYRENE BY NONBASIDIOMYCETE SOIL FUNGI	25	3
5931	11	9552 1995 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 73(1):146-152 SINAL CJ; ZHU LF; ZHONG R; CHERIAN MG; BEND JR LIVER-TRANSPLANTATION INDUCES CYTOCHROME-P450 1A1 DEPENDENT MONOOXYGENASE ACTIVITY IN RAT LUNG AND KIDNEY	6	3
5932	9	9553 1995 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 73(1):153-158 ALBORES A; SINAL CJ; CHERIAN MG; BEND JR SELECTIVE INCREASE OF RAT LUNG CYTOCHROME-P450 1A1 DEPENDENT MONOOXYGENASE ACTIVITY AFTER ACUTE SODIUM ARSENITE ADMINISTRATION	8	3
5933	17	9573 1995 CHEMICAL RESEARCH IN TOXICOLOGY 8(8):997-1004 ANARI MR; KHAN S; LIU ZC; OBRIEN PJ CYTOCHROME-P450 PEROXIDASE PEROXYGENASE MEDIATED XENOBIOTIC METABOLIC-ACTIVATION AND CYTOTOXICITY IN ISOLATED HEPATOCYTES	13	3
5934	5	9589 1995 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 110(4):683-688 DANIELSON PB; LETMAN JA; FOGLEMAN JC ALKALOID METABOLISM BY CYTOCHROME-P-450 ENZYMES IN DROSOPHILA- MELANOGASTER	5	3
5935	9	9603 1995 DNA AND CELL BIOLOGY 14(5):451-463 HUM DW; AZABLANC P; MILLER WL CHARACTERIZATION OF PLACENTAL TRANSCRIPTIONAL ACTIVATION OF THE HUMAN GENE FOR P450SCC	19	3
5936	8	9620 1995 DRUG METABOLISM AND DISPOSITION 23(8):818-824 KIM H; REDDY S; NOVAK RF 3-METHYLCHOLANTHRENE AND PYRIDINE EFFECTS ON CYP1A1 AND CYP1A2 EXPRESSION IN RAT RENAL TISSUE	14	3
5937	12	9628 1995 DRUG METABOLISM AND DISPOSITION 23(12):1379-1382 Franklin MR Enhanced rates of cytochrome P450 metabolic-intermediate complex formation from nonmacrolide amines in rifampicin- treated rabbit liver microsomes	5	3
5938	11	9651 1995 ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY 14(7):1159-1169 ANDERSON JW; ROSSI SS; TUKEY RH; VU T; QUATTROCHI LC A BIOMARKER, P450 RGS, FOR ASSESSING THE INDUCTION POTENTIAL OF ENVIRONMENTAL-SAMPLES	27	3
5939	16	9658 1995 EUROPEAN JOURNAL OF BIOCHEMISTRY 232(1):247-256 DELORME C; PIFFETEAU A; VIGER A; MARQUET A INHIBITION OF BOVINE CYTOCHROME P-450(11-BETA) BY 18- UNSATURATED PROGESTERONE DERIVATIVES	7	3
5940	10	9668 1995 FEBS LETTERS 365(2-3):101-107 JORGENSEN ECB; AUTRUP H EFFECT OF A NEGATIVE REGULATORY ELEMENT (NRE) ON THE HUMAN CYP1A1 GENE-EXPRESSION IN BREAST-CARCINOMA MCF-7 AND HEPATOMA HEPG2 CELLS	10	3
5941	15	9676 1995 FOOD AND CHEMICAL TOXICOLOGY 33(2):111-120 TAKAHASHI N; DASHWOOD RH; BJELDANES LF; BAILEY GS; WILLIAMS DE REGULATION OF HEPATIC CYTOCHROME P4501A BY INDOLE-3-CARBINOL - TRANSIENT INDUCTION WITH CONTINUOUS FEEDING IN RAINBOW-TROUT	19	3
5942	10	9683 1995 GASTROENTEROLOGY 109(5):1589-1599 TINEL M; ROBIN MA; DOOSTZADEH J; MARATRAT M; BALLET F; FARDEL N; ELKAHWAJI J; BEAUNE P; DAUJAT M; LABBE G; PESSAYRE D THE INTERLEUKIN-2 RECEPTOR DOWN-REGULATES THE EXPRESSION OF CYTOCHROME-P450 IN CULTURED RAT HEPATOCYTES	24	3
5943	11	9694 1995 HUMAN MOLECULAR GENETICS 4(11):2109-2116 TEE MK; BABALOLA GO; AZABLANC P; SPEEK M; GITELMAN SE; MILLER WL A PROMOTER WITHIN INTRON-35 OF THE HUMAN C4A GENE INITIATES ABUNDANT ADRENAL-SPECIFIC TRANSCRIPTION OF A 1 KB RNA - LOCATION OF A CRYPTIC CYP21 PROMOTER ELEMENT	25	3
5944	4	9698 1995 IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 17(2):283-300 HADASOVA E; SIEGMUND W; WALTER R; SCHEUCH E; FRANKE G EFFECTS OF STREPTOLYSIN-O, PICIBANIL (OK-432) AND INTERFERON ALPHA-2A ON CYTOCHROME P-450-DEPENDENT MONOOXYGENASES AND ARYLAMINE N-ACETYLTRANSFERASE IN RAT-LIVER	8	3
5945	4	9708 1995 INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 76(4):271-276 MURRAY GI; TAYLOR VE; MCKAY JA; WEAVER RJ; EWEN SWB; MELVIN WT; BURKE MD EXPRESSION OF XENOBIOTIC-METABOLIZING ENZYMES IN TUMORS OF THE URINARY-BLADDER	11	3
5946	8	9738 1995 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 80(8):2526-2529 OSHIRO C; TAKASU N; WAKUGAMI T; KOMIYA I; YAMADA T; EGUCHI Y; TAKEI H 17-ALPHA-HYDROXYLASE DEFICIENCY WITH ONE BASE-PAIR DELETION OF THE CYTOCHROME P450C17 (CYP17) GENE	14	3
5947	2	9750 1995 JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 43(6):571-577 ALMADHIDI J; SERALINI GE; FRESNEL J; SILBERZAHN P; GAILLARD JL IMMUNOHISTOCHEMICAL LOCALIZATION OF CYTOCHROME-P450 AROMATASE IN EQUINE GONADS	50	3
5948	29	9755 1995 JOURNAL OF LIPID MEDIATORS AND CELL SIGNALLING 12(2-3):229-242 SCHWARTZMAN ML; MCGIFF JC RENAL CYTOCHROME-P450	12	3
5949	10	9756 1995 JOURNAL OF LIPID MEDIATORS AND CELL SIGNALLING 12(2-3):243-255 TANABE T; ULLRICH V PROSTACYCLIN AND THROMBOXANE SYNTHASES	27	3
5950	12	9797 1995 LIPIDS 30(10):955-958 VALDES E; VEGA P; AVALOS N; ORELLANA M DIETARY FISH-OIL AND CYTOCHROME-P-450 MONOOXYGENASE ACTIVITY IN RAT-LIVER AND KIDNEY	9	3
5951	11	9815 1995 MOLECULAR ENDOCRINOLOGY 9(12):1771-1781 TOLLET P; LAHUNA O; AHLGREN R; MODE A; GUSTAFSSON JA CCAAT/ENHANCER-BINDING PROTEIN-ALPHA-DEPENDENT TRANSACTIVATION OF CYP2C12 IN RAT HEPATOCYTES	18	3
5952	3	9825 1995 NEURON 15(6):1383-1392 Freitag J; Krieger J; Strotmann J; Breer H Two grasses of olfactory receptors in Xenopus laevis	72	3
5953	11	9826 1995 NEUROSCIENCE LETTERS 200(3):203-206 Yamane M; Abe A Properties of the omega-hydroxylation system of docosahexaenoic or arachidonic acid in brain or liver homogenate of rat	3	3
5954	10	9832 1995 PESTICIDE SCIENCE 43(3):233-239 FEYEREISEN R; ANDERSEN JF; CARINO FA; COHEN MB; KOENER JF CYTOCHROME-P450 IN THE HOUSE-FLY - STRUCTURE, CATALYTIC ACTIVITY AND REGULATION OF EXPRESSION OF CYP6A1 IN AN INSECTICIDE-RESISTANT STRAIN	19	3
5955	10	9844 1995 PHARMACOLOGY 51(5):331-340 SHARMA MC; JEONG SJ; SHARMA MR; SHAPIRO BH SIMULTANEOUS ISOLATION OF NADPH-CYTOCHROME P-450 REDUCTASE AND CYTOCHROME-P-450 USING TENTACLE ION-EXCHANGE CHROMATOGRAPHY AND INTERSPECIES COMPARISON OF THE REDUCTASE-ACTIVITY	4	3
5956	6	9858 1995 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92(9):3764-3768 BESTERVELT LL; VAZ ADN; COON MJ INACTIVATION OF ETHANOL-INDUCIBLE CYTOCHROME-P450 AND OTHER MICROSOMAL P450 ISOZYMES BY TRANS-4-HYDROXY-2-NONENAL, A MAJOR PRODUCT OF MEMBRANE LIPID-PEROXIDATION	24	3
5957	13	9863 1995 PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 208(3):213-227 MASSEY TE; STEWART RK; DANIELS JM; LIU L BIOCHEMICAL AND MOLECULAR ASPECTS OF MAMMALIAN SUSCEPTIBILITY TO AFLATOXIN B-1 CARCINOGENICITY	55	3
5958	10	9889 1995 TOXICOLOGY AND APPLIED PHARMACOLOGY 135(2):246-253 Gebremichael A; Chang AM; Buckpitt AR; Plopper CG; Pinkerton KE Postnatal development of cytochrome P4501A1 and 2B1 in rat lung and liver: Effect of aged and diluted sidestream cigarette smoke	19	3
5959	10	9904 1995 XENOBIOTICA 25(7):711-724 KARKI SB; DINNOCENZO JP ON THE MECHANISM OF AMINE OXIDATIONS BY P450	19	3
5960	11	9909 1995 YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 115(5):370-377 KAMATAKI T MOLECULAR TOXICOLOGY OF CYTOCHROME-P450 - FOCUSING ON INTERSPECIES HOMOLOGY	4	3
5961	16	9927 1996 AMERICAN NATURALIST 148():S139-S155 Berenbaum MR; Favret C; Schuler MA On defining ''key innovations'' in an adaptive radiation: Cytochrome P450s and papilionidae	21	3
5962	12	9929 1996 ANALYTICAL BIOCHEMISTRY 233(1):100-107 Stresser DM; Dehal SS; Kupfer D Ring hydroxylation of [o-H-3]Methoxychlor as a probe for liver microsomal CYP2B activity: Potential for in vivo CYP2B assay	9	3
5963	8	9939 1996 APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 46(4):360-364 vandenBrink JM; vandenHondel CAMJJ; vanGorcom RFM Optimization ef the benzoate inducible benzoate p-hydroxylase cytochrome P450 enzyme system in Aspergillus niger	9	3
5964	6	9944 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 326(1):79-84 MacDonald MJ; Brown LJ Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied	23	3
5965	5	9967 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 330(2):271-280 OLeary KA; McQuiddy P; Kasper CB Transcriptional regulation of the TATA-less NADPH cytochrome P- 450 oxidoreductase gene	8	3
5966	23	9974 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 332(2):261-268 Hornsten L; Bylund J; Oliw EH Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes	9	3
5967	5	9981 1996 ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 334(2):349-356 Tazawa R; Green ED; Ohashi K; Wu KK; Wang LH Characterization of the complete genomic structure of human thromboxane synthase gene and functional analysis of its promoter	7	3
5968	7	10000 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 219(2):445-449 Bambal RB; Hanzlik RP Active site structure and substrate specificity of cytochrome P450 4A1: Steric control of ligand approach perpendicular to heme plane	10	3
5969	7	10009 1996 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 226(1):152-157 Jover R; Hoffmann K; Meyer UA Induction of 5-aminolevulinate synthase by drugs is independent of increased apocytochrome P450 synthesis	13	3
5970	11	10014 1996 BIOCHEMICAL PHARMACOLOGY 51(1):61-69 Hakkak R; Korourian S; Ronis MJJ; IngelmanSundberg M; Badger TM Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats	14	3
5971	6	10029 1996 BIOCHEMICAL PHARMACOLOGY 52(6):963-965 Trottier E; Dubois S; Jean A; Anderson A Identification of CYP2B14P and CYP2B16P, two apparent pseudogenes in the rat cytochrome P450 2B (CYP2B) subfamily	3	3
5972	15	10037 1996 BIOCHEMISTRY 35(20):6289-6296 Yu XC; Liang C; Strobel HW Kinetics of substrate reaction in the course of hydroperoxide- mediated inactivation of cytochrome P450 1A1	5	3
5973	1	10043 1996 BIOCHEMISTRY 35(38):12221-12227 Duester G Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis	129	3
5974	5	10050 1996 BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL 39(3):503-510 Shumyantseva VV; Bulko TV; Zimin AG; Uvarov VY; Archakov AI Design of an artificial hemoprotein based on human serum albumin	6	3
5975	14	10057 1996 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1289(2):238-246 Puntarulo S; Cederbaum AI Role of cytochrome P-450 in the stimulation of microsomal production of reactive oxygen species by ferritin	19	3
5976	21	10058 1996 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1290(3):327-339 Moghaddam MF; Motoba K; Borhan B; Pinot F; Hammock BD Novel metabolic pathways for linoleic and arachidonic acid metabolism	23	3
5977	3	10074 1996 BLOOD 87(2):725-733 Kizaki M; Ueno H; Yamazoe Y; Shimada M; Takayama N; Muto A; Matsushita H; Nakajima H; Morikawa M; Koeffler HP; Ikeda Y Mechanisms of retinoid resistance in leukemic cells: Possible role of cytochrome P450 and P-glycoprotein	55	3
5978	16	10084 1996 CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 74(2):150-156 Afsar A; Lee C; Riddick DS Modulation of the expression of constitutive rat hepatic cytochrome P450 isozymes by 5-fluorouracil	10	3
5979	19	10107 1996 CHEMICO-BIOLOGICAL INTERACTIONS 101(3):175-192 Wormhoudt LW; Ploemen JHTM; deWaziers I; Commandeur JNM; Beaune PH; vanBladeren PJ; Vermeulen NPE Inter-individual variability in the oxidation of 1,2- dibromoethane: Use of heterologously expressed human cytochrome P450 and human liver microsomes	9	3
5980	8	10108 1996 CHEMICO-BIOLOGICAL INTERACTIONS 102(3):155-167 Eke BC; Vural N; Iscan M Combined effects of ethanol and cigarette smoke on hepatic and pulmonary xenobiotic metabolizing enzymes in rats	5	3
5981	22	10117 1996 CLINICAL PHARMACOKINETICS 31(3):215-230 Pirmohamed M; Madden S; Park BK Idiosyncratic drug reactions - Metabolic bioactivation as a pathogenic mechanism	33	3
5982	9	10119 1996 COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY 113(1):175-183 Zhang ML; Scott JG Purification and characterization of cytochrome b(5) reductase from the house fly, Musca domestica	3	3
5983	2	10120 1996 COMPUTER APPLICATIONS IN THE BIOSCIENCES 12(3):237-240 Degtyarenko KN; Fabian P The directory of P450-containing systems on WorldWide Web	4	3
5984	3	10123 1996 CRITICAL REVIEWS IN TOXICOLOGY 26(2):213-249 Warshawsky D; Talaska G; Xue WL; Schneider J Comparative carcinogenicity, metabolism, mutagenicity, and DNA binding of 7H-dibenzo[c,g]carbazole and dibenz[a,j]acridine	26	3
5985	5	10135 1996 CYTOCHROME P450, PT B 272():275-283 Holton TA; Lester DR Cloning of novel cytochrome P450 gene sequences via polymerase chain reaction amplification	10	3
5986	25	10145 1996 DRUG METABOLISM AND DISPOSITION 24(2):164-171 Irshaid Y; Branch RA; Adedoyin A Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes	7	3
5987	20	10147 1996 DRUG METABOLISM AND DISPOSITION 24(4):401-407 Sewer MB; Koop DR; Morgan ET Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450	44	3
5988	8	10152 1996 DRUG METABOLISM AND DISPOSITION 24(6):619-627 Panesar SK; Bandiera SM; Abbott FS Comparative effects of carbamazepine and carbamazepine-10,11- epoxide on hepatic cytochromes P450 in the rat	11	3
5989	16	10154 1996 DRUG METABOLISM AND DISPOSITION 24(6):664-668 Laethem RM; Balazy M; Koop DR Expoxidation of C-18 unsaturated fatty acids by cytochromes P4502C2 and and P4502CAA	9	3
5990	6	10161 1996 DRUG METABOLISM AND DISPOSITION 24(11):1282-1285 Fang XJ; Halpert JR Dithionite-supported hydroxylation of palmitic acid by cytochrome P450BM-3	4	3
5991	5	10205 1996 GENE 169(1):105-109 Skaggs BA; Alexander JF; Pierson CA; Schweitzer KS; Chun KT; Koegel C; Barbuch R; Bard M Cloning and characterization of the Saccharomyces cerevisiae C- 22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis	27	3
5992	5	10206 1996 GENE 172(2):309-312 Brown LJ; Stoffel M; Moran SM; Fernald AA; Lehn DA; LeBeau MM; MacDonald MJ Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene	8	3
5993	19	10208 1996 GENERAL AND COMPARATIVE ENDOCRINOLOGY 102(2):173-182 Trant JM Heterologous expression of the spiny dogfish shark (Squalus acanthias) cytochrome P450c17 (17 alpha-hydroxylase) in Escherichia coli	5	3
5994	5	10233 1996 JOURNAL OF BIOCHEMISTRY 120(6):1082-1087 Nakahara K; Shoun H N-terminal processing and amino acid sequence of two isoforms of nitric oxide reductase cytochrome P450nor from Fusarium oxysporum	14	3
5995	6	10267 1996 JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS 678(1):105-111 Jones DR; Gorski JC; Hamman MA; Hall SD Quantification of dextromethorphan and metabolites: A dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity	24	3
5996	13	10273 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(1):321-326 Fardella CE; Hum DW; Rodriguez H; Zhang GR; Barry FL; Ilicki A; Bloch CA; Miller WL Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency	26	3
5997	5	10274 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(3):881-886 Moghetti P; Castello R; Negri C; Tosi F; Spiazzi GG; Brun E; Balducci R; Toscano V; Muggeo M Insulin infusion amplifies 17 alpha-hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: Apparent relative impairment of 17,20- lyase activity	67	3
5998	7	10276 1996 JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM 81(6):2389-2393 Skinner CA; Rumsby G; Honour JW Single strand conformation polymorphism (SSCP) analysis for the detection of mutations in the CYP11B1 gene	12	3
5999	9	10282 1996 JOURNAL OF CLINICAL PSYCHIATRY 57():17-25 Ereshefsky L; Riesenman C; Lam YWF Serotonin selective reuptake inhibitor drug interactions and the cytochrome P450 system	28	3
6000	9	10289 1996 JOURNAL OF COMPARATIVE NEUROLOGY 366(2):244-258 Norris PJ; Hardwick JP; Emson PC Regional distribution of cytochrome P450 2D1 in the rat central nervous system	21	3

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